official_symbol entrez_gene_id description go_terms go_types pubmed_id CARD11 84433 caspase recruitment domain family, member 11 positive regulation of cytokine production Biological process 12154360 PAX8 7849 paired box 8 branching involved in ureteric bud morphogenesis Biological process 1337742 CSNK2A1 1457 casein kinase 2, alpha 1 polypeptide PcG protein complex Cellular component 21282530 PPARG 5468 peroxisome proliferator-activated receptor gamma response to starvation Biological process - TAF1D 79101 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa regulation of gene expression, epigenetic Biological process - PURA 5813 purine-rich element binding protein A dendrite Cellular component - DGKG 1608 diacylglycerol kinase, gamma 90kDa plasma membrane Cellular component - VWA7 80737 von Willebrand factor A domain containing 7 extracellular region Cellular component - DTD1 92675 D-tyrosyl-tRNA deacylase 1 DNA binding Molecular function - TGFA 7039 transforming growth factor, alpha angiogenesis Biological process - P2RX3 5024 purinergic receptor P2X, ligand gated ion channel, 3 integral component of nuclear inner membrane Cellular component - RYR3 6263 ryanodine receptor 3 transmembrane transport Biological process - CTNS 1497 cystinosin, lysosomal cystine transporter long-term memory Biological process - LY6K 54742 lymphocyte antigen 6 complex, locus K anchored component of membrane Cellular component - TRIM38 10475 tripartite motif containing 38 positive regulation of NF-kappaB transcription factor activity Biological process 23077300 RHOBTB3 22836 Rho-related BTB domain containing 3 GTP binding Molecular function - ABCF2 10061 ATP-binding cassette, sub-family F (GCN20), member 2 transporter activity Molecular function 9878413 ALOX12B 242 arachidonate 12-lipoxygenase, 12R type oxidation-reduction process Biological process 15629692 RELA 5970 v-rel avian reticuloendotheliosis viral oncogene homolog A RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 17350185 TSPO 706 translocator protein (18kDa) protein binding Molecular function 25416956 FUT10 84750 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) fucosylation Biological process 11698403 APC 324 adenomatous polyposis coli negative regulation of microtubule depolymerization Biological process 17192415 ZNF395 55893 zinc finger protein 395 DNA binding Molecular function 14625278 FXN 2395 frataxin response to iron ion Biological process 18424449 TREH 11181 trehalase (brush-border membrane glycoprotein) anchored component of plasma membrane Cellular component 8773341 DRD1 1812 dopamine receptor D1 positive regulation of potassium ion transport Biological process - KCNT2 343450 potassium channel, sodium activated subfamily T, member 2 ATP binding Molecular function - TP53BP2 7159 tumor protein p53 binding protein 2 response to ionizing radiation Biological process - ZNF623 9831 zinc finger protein 623 DNA binding Molecular function - CCL23 6368 chemokine (C-C motif) ligand 23 inflammatory response Biological process - PPP1R1C 151242 protein phosphatase 1, regulatory (inhibitor) subunit 1C negative regulation of protein kinase activity Biological process - MYH15 22989 myosin, heavy chain 15 actin binding Molecular function - PSMC2 5701 proteasome (prosome, macropain) 26S subunit, ATPase, 2 membrane Cellular component 16210410 VDAC1 7416 voltage-dependent anion channel 1 pore complex Cellular component 9843949 MAPK9 5601 mitogen-activated protein kinase 9 JNK cascade Biological process - OR52N5 390075 olfactory receptor, family 52, subfamily N, member 5 G-protein coupled receptor signaling pathway Biological process - RFC1 5981 replication factor C (activator 1) 1, 145kDa ATP binding Molecular function - PLA2G2A 5320 phospholipase A2, group IIA (platelets, synovial fluid) mitochondrion Cellular component - ZNF766 90321 zinc finger protein 766 transcription, DNA-templated Biological process - NDUFA9 4704 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa mitochondrial electron transport, NADH to ubiquinone Biological process 9878551 RCAN1 1827 regulator of calcineurin 1 central nervous system development Biological process 8595418 FGD2 221472 FYVE, RhoGEF and PH domain containing 2 early endosome membrane Cellular component - HSD3B7 80270 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 integral component of membrane Cellular component - OASL 8638 2'-5'-oligoadenylate synthetase-like interferon-gamma-mediated signaling pathway Biological process - HERC2 8924 HECT and RLD domain containing E3 ubiquitin protein ligase 2 cellular protein metabolic process Biological process - PSMC2 5701 proteasome (prosome, macropain) 26S subunit, ATPase, 2 innate immune response Biological process - OR1J1 347168 olfactory receptor, family 1, subfamily J, member 1 detection of chemical stimulus involved in sensory perception of smell Biological process - OAZ3 51686 ornithine decarboxylase antizyme 3 small molecule metabolic process Biological process - LILRB5 10990 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 defense response Biological process 9548455 TNFRSF25 8718 tumor necrosis factor receptor superfamily, member 25 tumor necrosis factor-mediated signaling pathway Biological process 9052839 KRTAP4-8 728224 keratin associated protein 4-8 keratin filament Cellular component - HOXA4 3201 homeobox A4 anterior/posterior pattern specification Biological process - AMOT 154796 angiomotin establishment of cell polarity involved in ameboidal cell migration Biological process - STXBP5 134957 syntaxin binding protein 5 (tomosyn) regulation of gene expression Biological process 21810271 IL26 55801 interleukin 26 cytosol Cellular component 18483078 TMEM53 79639 transmembrane protein 53 integral component of membrane Cellular component - SFRP1 6422 secreted frizzled-related protein 1 extracellular space Cellular component 10980594 LTBR 4055 lymphotoxin beta receptor (TNFR superfamily, member 3) protein binding Molecular function 12393901 ICMT 23463 isoprenylcysteine carboxyl methyltransferase in utero embryonic development Biological process - TRIM26 7726 tripartite motif containing 26 negative regulation of viral entry into host cell Biological process 18248090 OR52I2 143502 olfactory receptor, family 52, subfamily I, member 2 olfactory receptor activity Molecular function - PDE4B 5142 phosphodiesterase 4B, cAMP-specific cellular response to drug Biological process - FGF19 9965 fibroblast growth factor 19 positive regulation of ERK1 and ERK2 cascade Biological process 17623664 TLN2 83660 talin 2 actin cytoskeleton Cellular component 10320934 NSD1 64324 nuclear receptor binding SET domain protein 1 chromosome Cellular component - CXCR4 7852 chemokine (C-X-C motif) receptor 4 germ cell development Biological process - CAT 847 catalase hydrogen peroxide catabolic process Biological process 18379038 PKD2 5311 polycystic kidney disease 2 (autosomal dominant) metanephric part of ureteric bud development Biological process 11891195 GTF2I 2969 general transcription factor IIi neuronal cell body Cellular component - LHX9 56956 LIM homeobox 9 protein binding Molecular function 25416956 IPO11 51194 importin 11 ribosomal protein import into nucleus Biological process - MYH4 4622 myosin, heavy chain 4, skeletal muscle sarcomere Cellular component 3904738 ODC1 4953 ornithine decarboxylase 1 cytoplasm Cellular component - NDUFB11 54539 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa respiratory electron transport chain Biological process - MARVELD2 153562 MARVEL domain containing 2 bicellular tight junction Cellular component 20164257 ASAP2 8853 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 enzyme activator activity Molecular function 9819391 HDAC6 10013 histone deacetylase 6 misfolded protein binding Molecular function - HMGN5 79366 high mobility group nucleosome binding domain 5 nucleus Cellular component 11161810 CRYAA 1409 crystallin, alpha A structural constituent of eye lens Molecular function - HENMT1 113802 HEN1 methyltransferase homolog 1 (Arabidopsis) gene silencing by RNA Biological process - QARS 5859 glutaminyl-tRNA synthetase ATP binding Molecular function - SPTBN1 6711 spectrin, beta, non-erythrocytic 1 nucleolus Cellular component 9537418 NPHP3 27031 nephronophthisis 3 (adolescent) convergent extension involved in gastrulation Biological process 18371931 SERPINE2 5270 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 protein binding Molecular function 19911255 ATP7A 538 ATPase, Cu++ transporting, alpha polypeptide release of cytochrome c from mitochondria Biological process - GRHL3 57822 grainyhead-like 3 (Drosophila) chromatin DNA binding Molecular function 21081122 HTR2A 3356 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled detection of temperature stimulus involved in sensory perception of pain Biological process - NOD1 10392 nucleotide-binding oligomerization domain containing 1 positive regulation of dendritic cell antigen processing and presentation Biological process - LLGL1 3996 lethal giant larvae homolog 1 (Drosophila) axon Cellular component - DRP2 1821 dystrophin related protein 2 cytoskeleton Cellular component - TDRP 157695 testis development related protein molecular_function Molecular function - FOXP3 50943 forkhead box P3 response to virus Biological process 20583921 P4HA1 5033 prolyl 4-hydroxylase, alpha polypeptide I mitochondrion Cellular component - MAPK11 5600 mitogen-activated protein kinase 11 stress-activated MAPK cascade Biological process - CHST5 23563 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 keratan sulfate biosynthetic process Biological process - STX6 10228 syntaxin 6 protein binding Molecular function 11384996 SMAD3 4088 SMAD family member 3 cytoplasm Cellular component - APOE 348 apolipoprotein E high-density lipoprotein particle assembly Biological process 17305370 LIG1 3978 ligase I, DNA, ATP-dependent response to hydrogen peroxide Biological process - TBC1D9B 23061 TBC1 domain family, member 9B (with GRAM domain) GTPase activator activity Molecular function - RAB35 11021 RAB35, member RAS oncogene family plasma membrane to endosome transport Biological process 17562788 FAP 2191 fibroblast activation protein, alpha apical part of cell Cellular component - OR8H2 390151 olfactory receptor, family 8, subfamily H, member 2 sensory perception of smell Biological process - ITSN1 6453 intersectin 1 (SH3 domain protein) calcium ion binding Molecular function 9799604 UBB 7314 ubiquitin B I-kappaB kinase/NF-kappaB signaling Biological process - GAL3ST2 64090 galactose-3-O-sulfotransferase 2 Golgi cisterna membrane Cellular component - CUL9 23113 cullin 9 zinc ion binding Molecular function - ITGA5 3678 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) blood coagulation Biological process - TUBB2B 347733 tubulin, beta 2B class IIb 'de novo' posttranslational protein folding Biological process - SOAT2 8435 sterol O-acyltransferase 2 intestinal cholesterol absorption Biological process 14615411 FKBP4 2288 FK506 binding protein 4, 59kDa heat shock protein binding Molecular function 9660753 GNRH1 2796 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) extracellular region Cellular component - TATDN2 9797 TatD DNase domain containing 2 metal ion binding Molecular function - PLCB4 5332 phospholipase C, beta 4 phosphatidylinositol phospholipase C activity Molecular function - KRT28 162605 keratin 28, type I intermediate filament Cellular component - PCDHB8 56128 protocadherin beta 8 integral component of membrane Cellular component - REL 5966 v-rel avian reticuloendotheliosis viral oncogene homolog I-kappaB kinase/NF-kappaB signaling Biological process - CALCOCO2 10241 calcium binding and coiled-coil domain 2 cytoskeleton Cellular component - USP21 27005 ubiquitin specific peptidase 21 cytoplasm Cellular component - ZNF569 148266 zinc finger protein 569 protein binding Molecular function 25416956 GRK7 131890 G protein-coupled receptor kinase 7 termination of G-protein coupled receptor signaling pathway Biological process - NDUFV1 4723 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa NADH dehydrogenase (ubiquinone) activity Molecular function 8288251 SOX3 6658 SRY (sex determining region Y)-box 3 sequence-specific DNA binding transcription factor activity Molecular function - SHROOM2 357 shroom family member 2 melanosome organization Biological process - SYT10 341359 synaptotagmin X integral component of membrane Cellular component - SIRT6 51548 sirtuin 6 NAD+ binding Molecular function - NLGN3 54413 neuroligin 3 protein binding Molecular function 17292328 VEGFA 7422 vascular endothelial growth factor A positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway Biological process 18440775 MRPS25 64432 mitochondrial ribosomal protein S25 mitochondrion Cellular component - CHSY1 22856 chondroitin sulfate synthase 1 extracellular region Cellular component 21129727 CPSF1 29894 cleavage and polyadenylation specific factor 1, 160kDa mRNA 3'-UTR binding Molecular function 7590244 TRPM3 80036 transient receptor potential cation channel, subfamily M, member 3 calcium channel activity Molecular function - LAMA5 3911 laminin, alpha 5 muscle organ development Biological process - SEC23A 10484 Sec23 homolog A (S. cerevisiae) COPII vesicle coat Cellular component - MAP3K11 4296 mitogen-activated protein kinase kinase kinase 11 JUN kinase kinase kinase activity Molecular function - CDCA3 83461 cell division cycle associated 3 cellular_component Cellular component - CCL3L3 414062 chemokine (C-C motif) ligand 3-like 3 chemokine activity Molecular function - KCNG2 26251 potassium channel, voltage gated modifier subfamily G, member 2 voltage-gated potassium channel complex Cellular component - HSPA8 3312 heat shock 70kDa protein 8 ATP metabolic process Biological process 23921388 P2RX7 5027 purinergic receptor P2X, ligand gated ion channel, 7 multicellular organismal protein catabolic process Biological process - ZCCHC17 51538 zinc finger, CCHC domain containing 17 nucleus Cellular component - TMEM219 124446 transmembrane protein 219 integral component of membrane Cellular component - KHDRBS1 10657 KH domain containing, RNA binding, signal transduction associated 1 SH3 domain binding Molecular function - MYLK 4638 myosin light chain kinase aorta smooth muscle tissue morphogenesis Biological process 21055718 RYR1 6261 ryanodine receptor 1 (skeletal) outflow tract morphogenesis Biological process - TAF7 6879 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa transcription from RNA polymerase II promoter Biological process 7824954 ZNF740 283337 zinc finger protein 740 nucleus Cellular component - PTK2 5747 protein tyrosine kinase 2 extrinsic component of cytoplasmic side of plasma membrane Cellular component - GNB2L1 10399 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 protein phosphatase binding Molecular function 11278757 HGF 3082 hepatocyte growth factor (hepapoietin A; scatter factor) mitotic nuclear division Biological process 2531289 HHIP 64399 hedgehog interacting protein dorsal/ventral pattern formation Biological process - MARK2 2011 MAP/microtubule affinity-regulating kinase 2 plasma membrane Cellular component 23902687 TACR1 6869 tachykinin receptor 1 response to ethanol Biological process - IFITM1 8519 interferon induced transmembrane protein 1 intracellular Cellular component 7559564 UBE2L6 9246 ubiquitin-conjugating enzyme E2L 6 protein ubiquitination Biological process - ITGB2 3689 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) protein kinase binding Molecular function 12885943 TAF1D 79101 TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa RNA polymerase transcription factor SL1 complex Cellular component - SPOCK1 6695 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 negative regulation of endopeptidase activity Biological process 14511383 MYL1 4632 myosin, light chain 1, alkali; skeletal, fast muscle filament sliding Biological process - DYNC1I1 1780 dynein, cytoplasmic 1, intermediate chain 1 microtubule binding Molecular function - NSUN6 221078 NOP2/Sun domain family, member 6 methylation Biological process - PRKCQ 5588 protein kinase C, theta membrane protein ectodomain proteolysis Biological process - RHCG 51458 Rh family, C glycoprotein amine transport Biological process 10852913 CRLF1 9244 cytokine receptor-like factor 1 negative regulation of motor neuron apoptotic process Biological process - TNIP1 10318 TNFAIP3 interacting protein 1 defense response Biological process 9923610 CYP4F11 57834 cytochrome P450, family 4, subfamily F, polypeptide 11 heme binding Molecular function 10964514 GTF2E1 2960 general transcription factor IIE, polypeptide 1, alpha 56kDa intermediate filament cytoskeleton Cellular component - DNAJC16 23341 DnaJ (Hsp40) homolog, subfamily C, member 16 cell Cellular component - RUNX2 860 runt-related transcription factor 2 regulation of fibroblast growth factor receptor signaling pathway Biological process - C12orf66 144577 chromosome 12 open reading frame 66 microtubule cytoskeleton Cellular component - F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 defense response to virus Biological process 18453611 PAPD7 11044 PAP associated domain containing 7 cell division Biological process - STX4 6810 syntaxin 4 perinuclear region of cytoplasm Cellular component - NGLY1 55768 N-glycanase 1 metal ion binding Molecular function - DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) Wnt signaling pathway Biological process - BLVRB 645 biliverdin reductase B oxidation-reduction process Biological process - WNT10A 80326 wingless-type MMTV integration site family, member 10A cell fate commitment Biological process - USP24 23358 ubiquitin specific peptidase 24 ubiquitin-specific protease activity Molecular function - FGF4 2249 fibroblast growth factor 4 mesenchymal cell proliferation Biological process 11023873 SSTR2 6752 somatostatin receptor 2 plasma membrane Cellular component - VCPKMT 79609 valosin containing protein lysine (K) methyltransferase peptidyl-lysine trimethylation Biological process 22948820 VIMP 55829 VCP-interacting membrane selenoprotein negative regulation of glucose import Biological process 12663463 IL33 90865 interleukin 33 positive regulation of type 2 immune response Biological process - ETV1 2115 ets variant 1 nucleus Cellular component - IQGAP1 8826 IQ motif containing GTPase activating protein 1 neuron projection extension Biological process 15695813 PKD1 5310 polycystic kidney disease 1 (autosomal dominant) basolateral plasma membrane Cellular component 10770959 FAS 355 Fas cell surface death receptor regulation of necrotic cell death Biological process - AKR1B1 231 aldo-keto reductase family 1, member B1 (aldose reductase) response to stress Biological process 8435445 F9 2158 coagulation factor IX proteolysis Biological process - RPS23 6228 ribosomal protein S23 SRP-dependent cotranslational protein targeting to membrane Biological process - SEPHS1 22929 selenophosphate synthetase 1 nuclear membrane Cellular component - TMEM106C 79022 transmembrane protein 106C protein binding Molecular function 25416956 HSF1 3297 heat shock transcription factor 1 pronucleus Cellular component - HYAL1 3373 hyaluronoglucosaminidase 1 response to antibiotic Biological process 11944887 YTHDC2 64848 YTH domain containing 2 endoplasmic reticulum Cellular component 21559518 GABRA5 2558 gamma-aminobutyric acid (GABA) A receptor, alpha 5 inner ear receptor cell development Biological process - FOXM1 2305 forkhead box M1 DNA repair Biological process - STXBP4 252983 syntaxin binding protein 4 protein stabilization Biological process 19451233 GPR180 160897 G protein-coupled receptor 180 integral component of membrane Cellular component - USP13 8975 ubiquitin specific peptidase 13 (isopeptidase T-3) ubiquitin binding Molecular function 21659512 SOX9 6662 SRY (sex determining region Y)-box 9 positive regulation of cartilage development Biological process 21401405 ARNT 405 aryl hydrocarbon receptor nuclear translocator enhancer binding Molecular function 23275542 UBE2W 55284 ubiquitin-conjugating enzyme E2W (putative) protein monoubiquitination Biological process 21229326 COL14A1 7373 collagen, type XIV, alpha 1 proteinaceous extracellular matrix Cellular component 2187872 SEMA3A 10371 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A regulation of axon extension involved in axon guidance Biological process 18053124 BGLAP 632 bone gamma-carboxyglutamate (gla) protein response to gravity Biological process - UGT3A2 167127 UDP glycosyltransferase 3 family, polypeptide A2 integral component of membrane Cellular component - IL5RA 3568 interleukin 5 receptor, alpha plasma membrane Cellular component - HDAC4 9759 histone deacetylase 4 nucleoplasm Cellular component - TENM4 26011 teneurin transmembrane protein 4 cytoplasm Cellular component - KRT19 3880 keratin 19, type I sarcomere organization Biological process 16000376 TMC5 79838 transmembrane channel-like 5 extracellular exosome Cellular component 23533145 ABI1 10006 abl-interactor 1 cytoskeleton Cellular component - HIPK3 10114 homeodomain interacting protein kinase 3 apoptotic process Biological process - IGKV3D-20 28874 immunoglobulin kappa variable 3D-20 antigen binding Molecular function 5027703 BCL11B 64919 B-cell CLL/lymphoma 11B (zinc finger protein) transcription, DNA-templated Biological process - RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 ripoptosome assembly involved in necroptotic process Biological process - SUFU 51684 suppressor of fused homolog (Drosophila) protein binding Molecular function 10564661 SFPQ 6421 splicing factor proline/glutamine-rich regulation of circadian rhythm Biological process - C19orf44 84167 chromosome 19 open reading frame 44 protein binding Molecular function 25416956 SLC32A1 140679 solute carrier family 32 (GABA vesicular transporter), member 1 clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane Cellular component - NAPA 8775 N-ethylmaleimide-sensitive factor attachment protein, alpha protein binding Molecular function 15029241 PRB3 5544 proline-rich protein BstNI subfamily 3 defense response to Gram-negative bacterium Biological process 1894623 HOXA11 3207 homeobox A11 cartilage development involved in endochondral bone morphogenesis Biological process - ABLIM3 22885 actin binding LIM protein family, member 3 cilium assembly Biological process 22684256 LYN 4067 LYN proto-oncogene, Src family tyrosine kinase positive regulation of cell proliferation Biological process - TMPRSS5 80975 transmembrane protease, serine 5 scavenger receptor activity Molecular function - IL6ST 3572 interleukin 6 signal transducer interleukin-6 receptor complex Cellular component 12643274 BPIFA1 51297 BPI fold containing family A, member 1 extracellular space Cellular component 24124190 RORA 6095 RAR-related orphan receptor A beta-catenin binding Molecular function - NCOA3 8202 nuclear receptor coactivator 3 signal transducer activity Molecular function - GHRHR 2692 growth hormone releasing hormone receptor secretory granule Cellular component 10461027 ATP13A5 344905 ATPase type 13A5 plasma membrane Cellular component - RABL2A 11159 RAB, member of RAS oncogene family-like 2A protein binding Molecular function 25416956 NR1H4 9971 nuclear receptor subfamily 1, group H, member 4 intracellular receptor signaling pathway Biological process - COMMD2 51122 COMM domain containing 2 regulation of transcription, DNA-templated Biological process - CPNE6 9362 copine VI (neuronal) dendrite Cellular component - SSTR5 6755 somatostatin receptor 5 plasma membrane Cellular component - ATP6V0C 527 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c insulin receptor signaling pathway Biological process - MICA 100507436 MHC class I polypeptide-related sequence A negative regulation of natural killer cell mediated cytotoxicity Biological process 20068167 MMP17 4326 matrix metallopeptidase 17 (membrane-inserted) proteinaceous extracellular matrix Cellular component - CDK5R2 8941 cyclin-dependent kinase 5, regulatory subunit 2 (p39) cyclin-dependent protein kinase 5 holoenzyme complex Cellular component - IL1B 3553 interleukin 1, beta protein domain specific binding Molecular function 16575408 PDCL3 79031 phosducin-like 3 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Biological process 23792958 PRKD2 25865 protein kinase D2 cell death Biological process 17077180 ZNF701 55762 zinc finger protein 701 regulation of transcription, DNA-templated Biological process - WIPF2 147179 WAS/WASL interacting protein family, member 2 actin binding Molecular function - MYOCD 93649 myocardin transcription factor binding Molecular function 16054032 SOX9 6662 SRY (sex determining region Y)-box 9 negative regulation of myoblast differentiation Biological process - SERPINF2 5345 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 cell surface Cellular component 17958745 CFL1 1072 cofilin 1 (non-muscle) mitotic cytokinesis Biological process - AKR1C3 8644 aldo-keto reductase family 1, member C3 farnesol catabolic process Biological process 21187079 PHYKPL 85007 5-phosphohydroxy-L-lysine phospho-lyase mitochondrion Cellular component - SLC2A9 56606 solute carrier family 2 (facilitated glucose transporter), member 9 glucose transmembrane transporter activity Molecular function - SEMA5A 9037 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A positive regulation of axon extension involved in axon guidance Biological process - PGR 5241 progesterone receptor progesterone receptor signaling pathway Biological process - KCNH1 3756 potassium channel, voltage gated eag related subfamily H, member 1 integral component of plasma membrane Cellular component 22732247 LCK 3932 LCK proto-oncogene, Src family tyrosine kinase peptidyl-tyrosine autophosphorylation Biological process - SCN8A 6334 sodium channel, voltage gated, type VIII alpha subunit neuronal cell body Cellular component - CENPU 79682 centromere protein U cytosol Cellular component - FOXD4L5 653427 forkhead box D4-like 5 cell differentiation Biological process - FCMR 9214 Fc fragment of IgM receptor cellular defense response Biological process 9586636 POLRMT 5442 polymerase (RNA) mitochondrial (DNA directed) transcription from mitochondrial promoter Biological process 17337445 CPT1A 1374 carnitine palmitoyltransferase 1A (liver) integral component of mitochondrial outer membrane Cellular component - DNM2 1785 dynamin 2 negative regulation of membrane tubulation Biological process 18388313 NISCH 11188 nischarin early endosome Cellular component - MAG 4099 myelin associated glycoprotein substantia nigra development Biological process 22926577 RAB14 51552 RAB14, member RAS oncogene family intracellular transport Biological process 15004230 JUN 3725 jun proto-oncogene learning Biological process - AASDH 132949 aminoadipate-semialdehyde dehydrogenase acid-thiol ligase activity Molecular function - H3F3A 3020 H3 histone, family 3A protein binding Molecular function 19494831 IGF2 3481 insulin-like growth factor 2 protein serine/threonine kinase activator activity Molecular function - TMEM115 11070 transmembrane protein 115 Golgi apparatus Cellular component 17973242 KRT13 3860 keratin 13, type I keratin filament Cellular component 9714826 CALM3 808 calmodulin 3 (phosphorylase kinase, delta) regulation of cell communication by electrical coupling involved in cardiac conduction Biological process - PABPC4 8761 poly(A) binding protein, cytoplasmic 4 (inducible form) poly(C) RNA binding Molecular function 8524242 AMY1A 276 amylase, alpha 1A (salivary) extracellular exosome Cellular component 19199708 VARS2 57176 valyl-tRNA synthetase 2, mitochondrial cytosol Cellular component - RARA 5914 retinoic acid receptor, alpha nuclear chromatin Cellular component 17363140 MSLN 10232 mesothelin extracellular space Cellular component - GNAS 2778 GNAS complex locus renal water homeostasis Biological process - TAF1B 9014 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa TBP-class protein binding Molecular function 21921199 SFTPB 6439 surfactant protein B organ morphogenesis Biological process 10378403 LRRC52 440699 leucine rich repeat containing 52 ion transport Biological process - JUP 3728 junction plakoglobin protein homodimerization activity Molecular function - CFAP43 80217 cilia and flagella associated protein 43 cell projection Cellular component - MAP1S 55201 microtubule-associated protein 1S microtubule bundle formation Biological process 15528209 GFI1 2672 growth factor independent 1 transcription repressor auditory receptor cell differentiation Biological process - RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 protein autophosphorylation Biological process 8612133 PAOX 196743 polyamine oxidase (exo-N4-amino) putrescine biosynthetic process Biological process 16354669 SCN1B 6324 sodium channel, voltage gated, type I beta subunit regulation of heart rate by cardiac conduction Biological process 19808477 CRYAB 1410 crystallin, alpha B protein folding Biological process - RBMX 27316 RNA binding motif protein, X-linked nucleotide binding Molecular function - HIST1H3I 8354 histone cluster 1, H3i DNA binding Molecular function - SOCS3 9021 suppressor of cytokine signaling 3 spongiotrophoblast differentiation Biological process - RASA4 10156 RAS p21 protein activator 4 positive regulation of GTPase activity Biological process - VHL 7428 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase positive regulation of cell differentiation Biological process 12169691 HOXA10 3206 homeobox A10 transcription, DNA-templated Biological process - GATA4 2626 GATA binding protein 4 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function - MAP2 4133 microtubule-associated protein 2 microtubule Cellular component - PLCB1 23236 phospholipase C, beta 1 (phosphoinositide-specific) interleukin-15-mediated signaling pathway Biological process 11743656 UBC 7316 ubiquitin C carbohydrate metabolic process Biological process - CCL25 6370 chemokine (C-C motif) ligand 25 chemotaxis Biological process 10640743 NR1H3 10062 nuclear receptor subfamily 1, group H, member 3 positive regulation of fatty acid biosynthetic process Biological process 17186944 TLR10 81793 toll-like receptor 10 toll-like receptor 5 signaling pathway Biological process - NOVA1 4857 neuro-oncological ventral antigen 1 synaptic transmission Biological process 8558240 RET 5979 ret proto-oncogene signal transduction Biological process 7824936 ID4 3400 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein circadian rhythm Biological process - SRRT 51593 serrate, RNA effector molecule primary miRNA processing Biological process 19632182 NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 FK506 binding Molecular function 8702849 PPM1E 22843 protein phosphatase, Mg2+/Mn2+ dependent, 1E nucleolus Cellular component - HSPB2 3316 heat shock 27kDa protein 2 cytosol Cellular component 9490724 MTRF1L 54516 mitochondrial translational release factor 1-like mitochondrial matrix Cellular component - PTPN22 26191 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) negative regulation of T cell activation Biological process 18299186 CHUK 1147 conserved helix-loop-helix ubiquitous kinase inflammatory response Biological process 18626576 S1PR1 1901 sphingosine-1-phosphate receptor 1 sphingolipid binding Molecular function - DDX60 55601 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 protein binding Molecular function 21791617 F8 2157 coagulation factor VIII, procoagulant component proteolysis Biological process - STK36 27148 serine/threonine kinase 36 epithelial cilium movement Biological process - NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - ADAMTS16 170690 ADAM metallopeptidase with thrombospondin type 1 motif, 16 metalloendopeptidase activity Molecular function - RAB9A 9367 RAB9A, member RAS oncogene family plasma membrane Cellular component - ACTG1 71 actin gamma 1 plasma membrane Cellular component - CENPW 387103 centromere protein W protein heterodimerization activity Molecular function - EIF3I 8668 eukaryotic translation initiation factor 3, subunit I formation of translation preinitiation complex Biological process - TOX3 27324 TOX high mobility group box family member 3 transcription, DNA-templated Biological process - KL 9365 klotho energy reserve metabolic process Biological process - MOV10 4343 Mov10 RISC complex RNA helicase poly(A) RNA binding Molecular function 22658674 CNGA1 1259 cyclic nucleotide gated channel alpha 1 potassium ion transmembrane transport Biological process - CACNA1D 776 calcium channel, voltage-dependent, L type, alpha 1D subunit regulation of heart rate by cardiac conduction Biological process 21131953 AOC3 8639 amine oxidase, copper containing 3 calcium ion binding Molecular function 19764817 CYP2D6 1565 cytochrome P450, family 2, subfamily D, polypeptide 6 xenobiotic metabolic process Biological process 19438707 RRAGC 64121 Ras-related GTP binding C intracellular membrane-bounded organelle Cellular component - MTA1 9112 metastasis associated 1 core promoter binding Molecular function 21965678 DNMT3A 1788 DNA (cytosine-5-)-methyltransferase 3 alpha cytoplasm Cellular component 12138111 HIST2H3D 653604 histone cluster 2, H3d blood coagulation Biological process - NPM1 4869 nucleophosmin (nucleolar phosphoprotein B23, numatrin) intracellular protein transport Biological process 12080348 GREM1 26585 gremlin 1, DAN family BMP antagonist cell surface Cellular component - KDM5A 5927 lysine (K)-specific demethylase 5A transcription from RNA polymerase II promoter Biological process 8414517 TGFBR1 7046 transforming growth factor, beta receptor 1 ATP binding Molecular function 12065756 RBX1 9978 ring-box 1, E3 ubiquitin protein ligase Cul4A-RING E3 ubiquitin ligase complex Cellular component 12732143 HAS3 3038 hyaluronan synthase 3 glycosaminoglycan metabolic process Biological process - HIST1H2AI 8329 histone cluster 1, H2ai enzyme binding Molecular function 17980597 SLC39A14 23516 solute carrier family 39 (zinc transporter), member 14 zinc ion transmembrane transporter activity Molecular function 15642354 MSH3 4437 mutS homolog 3 somatic recombination of immunoglobulin gene segments Biological process - TAF4 6874 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa transcription initiation from RNA polymerase II promoter Biological process - SERPINE2 5270 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 detection of mechanical stimulus involved in sensory perception Biological process - CSTF1 1477 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa poly(A) RNA binding Molecular function 22658674 ZNF678 339500 zinc finger protein 678 regulation of transcription, DNA-templated Biological process - CHRM1 1128 cholinergic receptor, muscarinic 1 nervous system development Biological process 2739737 XPO1 7514 exportin 1 transporter activity Molecular function - GSK3B 2932 glycogen synthase kinase 3 beta nucleoplasm Cellular component - TBC1D3 729873 TBC1 domain family, member 3 regulation of cilium assembly Biological process 17646400 PCNT 5116 pericentrin centriole Cellular component 24421332 ZSCAN23 222696 zinc finger and SCAN domain containing 23 transcription, DNA-templated Biological process - ATM 472 ATM serine/threonine kinase V(D)J recombination Biological process - USP17L8 392188 ubiquitin specific peptidase 17-like family member 8 ubiquitinyl hydrolase activity Molecular function - SEC24B 10427 SEC24 family member B COPII vesicle coating Biological process - RETN 56729 resistin positive regulation of collagen metabolic process Biological process - FAM74A4 401508 family with sequence similarity 74, member A4 protein binding Molecular function 25416956 FOXF1 2294 forkhead box F1 smooth muscle cell differentiation Biological process - POR 5447 P450 (cytochrome) oxidoreductase nitric oxide dioxygenase activity Molecular function - NR2C1 7181 nuclear receptor subfamily 2, group C, member 1 zinc ion binding Molecular function - DLG4 1742 discs, large homolog 4 (Drosophila) PDZ domain binding Molecular function - RAD51C 5889 RAD51 paralog C positive regulation of G2/M transition of mitotic cell cycle Biological process 23108668 TNF 7124 tumor necrosis factor negative regulation of gene expression Biological process 15345745 NAA10 8260 N(alpha)-acetyltransferase 10, NatA catalytic subunit N-terminal peptidyl-glutamic acid acetylation Biological process - CLDN19 149461 claudin 19 cytoplasm Cellular component - ACPP 55 acid phosphatase, prostate purine nucleobase metabolic process Biological process - GORAB 92344 golgin, RAB6-interacting nucleolus Cellular component - IL18 3606 interleukin 18 immune response Biological process 8999896 NPFFR2 10886 neuropeptide FF receptor 2 neuropeptide receptor activity Molecular function - SNX33 257364 sorting nexin 33 cleavage furrow formation Biological process 22718350 ARHGEF2 9181 Rho/Rac guanine nucleotide exchange factor (GEF) 2 positive regulation of NF-kappaB transcription factor activity Biological process 19043560 RORB 6096 RAR-related orphan receptor B retinal rod cell development Biological process - BRK1 55845 BRICK1, SCAR/WAVE actin-nucleating complex subunit cytosol Cellular component - PTGIS 5740 prostaglandin I2 (prostacyclin) synthase apoptotic signaling pathway Biological process 11551955 CPLX4 339302 complexin 4 cell Cellular component - IGHV3-23 28442 immunoglobulin heavy variable 3-23 Fc-gamma receptor signaling pathway involved in phagocytosis Biological process - VRK3 51231 vaccinia related kinase 3 protein phosphatase binding Molecular function 22572157 MORF4L2 9643 mortality factor 4 like 2 positive regulation of striated muscle cell differentiation Biological process - SDPR 8436 serum deprivation response cytosol Cellular component 2390065 FURIN 5045 furin (paired basic amino acid cleaving enzyme) peptide hormone processing Biological process 9242664 NELL2 4753 NEL-like 2 (chicken) calcium ion binding Molecular function - SLIT2 9353 slit homolog 2 (Drosophila) mammary duct terminal end bud growth Biological process - PFDN6 10471 prefoldin subunit 6 'de novo' posttranslational protein folding Biological process - OR52A5 390054 olfactory receptor, family 52, subfamily A, member 5 detection of chemical stimulus involved in sensory perception of smell Biological process 11121057 SORBS1 10580 sorbin and SH3 domain containing 1 stress fiber assembly Biological process - TGFB1 7040 transforming growth factor, beta 1 growth factor activity Molecular function - SLC18A2 6571 solute carrier family 18 (vesicular monoamine transporter), member 2 synaptic transmission Biological process 15217342 UBA3 9039 ubiquitin-like modifier activating enzyme 3 cellular protein modification process Biological process 9694792 REPIN1 29803 replication initiator 1 cytosolic ribosome Cellular component - ASPSCR1 79058 alveolar soft part sarcoma chromosome region, candidate 1 perinuclear region of cytoplasm Cellular component - IGFL3 388555 IGF-like family member 3 extracellular region Cellular component - CITED1 4435 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 negative regulation of osteoblast differentiation Biological process - RCL1 10171 RNA terminal phosphate cyclase-like 1 nucleolus Cellular component - GNL2 29889 guanine nucleotide binding protein-like 2 (nucleolar) nucleus Cellular component 8822211 SPATA20 64847 spermatogenesis associated 20 cell differentiation Biological process - SMAD3 4088 SMAD family member 3 embryonic cranial skeleton morphogenesis Biological process - THOC1 9984 THO complex 1 nucleoplasm Cellular component - KCNN3 3782 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 plasma membrane Cellular component - TMEM192 201931 transmembrane protein 192 perinuclear region of cytoplasm Cellular component 22736246 ZNF175 7728 zinc finger protein 175 intermediate filament cytoskeleton Cellular component - CACYBP 27101 calcyclin binding protein cellular response to calcium ion Biological process - GGTLC2 91227 gamma-glutamyltransferase light chain 2 glutathione metabolic process Biological process 18357469 PRKCE 5581 protein kinase C, epsilon actin monomer binding Molecular function - SELPLG 6404 selectin P ligand leukocyte migration Biological process - KRT12 3859 keratin 12, type I epithelium development Biological process - PRAMEF2 65122 PRAME family member 2 negative regulation of cell differentiation Biological process - OXNAD1 92106 oxidoreductase NAD-binding domain containing 1 biological_process Biological process - SPEF1 25876 sperm flagellar 1 biological_process Biological process - HIC2 23119 hypermethylated in cancer 2 plasma membrane Cellular component - TMEM63A 9725 transmembrane protein 63A extracellular exosome Cellular component 19056867 NME1 4830 NME/NM23 nucleoside diphosphate kinase 1 nucleoside triphosphate biosynthetic process Biological process - HERC5 51191 HECT and RLD domain containing E3 ubiquitin protein ligase 5 defense response to virus Biological process - DDX23 9416 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 poly(A) RNA binding Molecular function 22681889 HIST1H3J 8356 histone cluster 1, H3j nucleosome assembly Biological process 25615412 PGRMC1 10857 progesterone receptor membrane component 1 integral component of membrane Cellular component - SIRT7 51547 sirtuin 7 NAD-dependent histone deacetylase activity (H3-K18 specific) Molecular function 22722849 CXXC1 30827 CXXC finger protein 1 nucleus Cellular component - DOCK2 1794 dedicator of cytokinesis 2 negative thymic T cell selection Biological process - DST 667 dystonin cytoskeleton organization Biological process 19403692 PIK3R2 5296 phosphoinositide-3-kinase, regulatory subunit 2 (beta) epidermal growth factor receptor signaling pathway Biological process - BACE1 23621 beta-site APP-cleaving enzyme 1 Golgi apparatus Cellular component 10531052 RGS5 8490 regulator of G-protein signaling 5 cytoplasm Cellular component - MGST1 4257 microsomal glutathione S-transferase 1 cellular response to lipid hydroperoxide Biological process 20727966 TKFC 26007 triokinase/FMN cyclase triokinase activity Molecular function 4688871 GFI1 2672 growth factor independent 1 transcription repressor negative regulation of transcription, DNA-templated Biological process 12874834 Mar-01 55016 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase trans-Golgi network membrane Cellular component - AKR1C8P 340811 aldo-keto reductase family 1, member C8, pseudogene oxidation-reduction process Biological process - NOX1 27035 NADPH oxidase 1 plasma membrane Cellular component - HBEGF 1839 heparin-binding EGF-like growth factor integral component of plasma membrane Cellular component 15389565 C12orf4 57102 chromosome 12 open reading frame 4 regulation of mast cell degranulation Biological process - INVS 27130 inversin post-embryonic development Biological process - SALL1 6299 spalt-like transcription factor 1 histone deacetylation Biological process - SLC2A7 155184 solute carrier family 2 (facilitated glucose transporter), member 7 hexose transmembrane transport Biological process - GGACT 87769 gamma-glutamylamine cyclotransferase protein binding Molecular function 25416956 FXN 2395 frataxin positive regulation of cell growth Biological process 15509595 MFF 56947 mitochondrial fission factor cell junction Cellular component - ABLIM3 22885 actin binding LIM protein family, member 3 lamellipodium assembly Biological process 22684256 WDR5 11091 WD repeat domain 5 Set1C/COMPASS complex Cellular component 17998332 HPRT1 3251 hypoxanthine phosphoribosyltransferase 1 cytosol Cellular component - RAD51B 5890 RAD51 paralog B nucleus Cellular component 9512535 SNX9 51429 sorting nexin 9 endocytosis Biological process 22718350 SLC3A1 6519 solute carrier family 3 (amino acid transporter heavy chain), member 1 plasma membrane Cellular component - NDC1 55706 NDC1 transmembrane nucleoporin membrane Cellular component 19946888 CCNB2 9133 cyclin B2 in utero embryonic development Biological process - RAD51B 5890 RAD51 paralog B reciprocal meiotic recombination Biological process 9441753 IGHMBP2 3508 immunoglobulin mu binding protein 2 ATP binding Molecular function 19158098 OAS1 4938 2'-5'-oligoadenylate synthetase 1, 40/46kDa negative regulation of viral genome replication Biological process 18931074 USB1 79650 U6 snRNA biogenesis 1 3'-5'-exoribonuclease activity Molecular function 23190533 BBS4 585 Bardet-Biedl syndrome 4 beta-tubulin binding Molecular function 17574030 GNL3L 54552 guanine nucleotide binding protein-like 3 (nucleolar)-like ribosome biogenesis Biological process - RREB1 6239 ras responsive element binding protein 1 cytoplasm Cellular component 9305772 USP17L2 377630 ubiquitin specific peptidase 17-like family member 2 regulation of cell proliferation Biological process 19188362 MGAT2 4247 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase post-translational protein modification Biological process - ARHGDIB 397 Rho GDP dissociation inhibitor (GDI) beta multicellular organismal development Biological process 8434008 CSGALNACT1 55790 chondroitin sulfate N-acetylgalactosaminyltransferase 1 metal ion binding Molecular function 12163485 GCG 2641 glucagon small molecule metabolic process Biological process - SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) microtubule binding Molecular function - SCN4B 6330 sodium channel, voltage gated, type IV beta subunit regulation of sodium ion transmembrane transporter activity Biological process 17592081 YEATS2 55689 YEATS domain containing 2 chromatin organization Biological process - RAC1 5879 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) positive regulation of substrate adhesion-dependent cell spreading Biological process 23129259 YWHAG 7532 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma protein kinase C binding Molecular function 10433554 SLC43A1 8501 solute carrier family 43 (amino acid system L transporter), member 1 integral component of plasma membrane Cellular component 12930836 ERGIC1 57222 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 endoplasmic reticulum-Golgi intermediate compartment membrane Cellular component - AIMP1 9255 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 chemotaxis Biological process 7545917 DDC 1644 dopa decarboxylase (aromatic L-amino acid decarboxylase) cellular response to alkaloid Biological process - TIMM23 100287932 translocase of inner mitochondrial membrane 23 homolog (yeast) mitochondrial inner membrane Cellular component 14726512 TGFBR1 7046 transforming growth factor, beta receptor 1 activin receptor signaling pathway Biological process - CASK 8573 calcium/calmodulin-dependent serine protein kinase (MAGUK family) extracellular matrix organization Biological process - FMNL1 752 formin-like 1 plasma membrane Cellular component - SRGN 5552 serglycin platelet activation Biological process - CLEC4A 50856 C-type lectin domain family 4, member A transmembrane signaling receptor activity Molecular function 10438934 CAMK2G 818 calcium/calmodulin-dependent protein kinase II gamma regulation of calcium ion transport Biological process 15294044 HLA-DQB2 3120 major histocompatibility complex, class II, DQ beta 2 antigen processing and presentation of exogenous peptide antigen via MHC class II Biological process - SETDB2 83852 SET domain, bifurcated 2 protein binding Molecular function 25416956 TRIM38 10475 tripartite motif containing 38 signal transducer activity Molecular function 12761501 CLDN16 10686 claudin 16 integral component of membrane Cellular component - SRMS 6725 src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites non-membrane spanning protein tyrosine kinase activity Molecular function - RNMT 8731 RNA (guanine-7-) methyltransferase nucleoplasm Cellular component - MDH2 4191 malate dehydrogenase 2, NAD (mitochondrial) oxaloacetate metabolic process Biological process - PSMD13 5719 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - MICB 4277 MHC class I polypeptide-related sequence B natural killer cell mediated cytotoxicity Biological process - WNT11 7481 wingless-type MMTV integration site family, member 11 non-canonical Wnt signaling pathway Biological process - METTL2A 339175 methyltransferase like 2A tRNA methylation Biological process - GAPDH 2597 glyceraldehyde-3-phosphate dehydrogenase ribonucleoprotein complex Cellular component 15479637 SMPD4 55627 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) trans-Golgi network Cellular component 16517606 UCK1 83549 uridine-cytidine kinase 1 nucleobase-containing small molecule metabolic process Biological process - LIPG 9388 lipase, endothelial cholesterol homeostasis Biological process 19136670 SAFB 6294 scaffold attachment factor B hormone metabolic process Biological process - CSF3R 1441 colony stimulating factor 3 receptor (granulocyte) integral component of plasma membrane Cellular component 7542747 IL2RB 3560 interleukin 2 receptor, beta interleukin-2 binding Molecular function - OR51B4 79339 olfactory receptor, family 51, subfamily B, member 4 G-protein coupled receptor activity Molecular function - OR56B2P 390073 olfactory receptor, family 56, subfamily B, member 2 pseudogene G-protein coupled receptor activity Molecular function - ELOVL4 6785 ELOVL fatty acid elongase 4 fatty acid elongation, saturated fatty acid Biological process 20937905 FABP4 2167 fatty acid binding protein 4, adipocyte cytoplasm Cellular component 16130169 ZAR1 326340 zygote arrest 1 cytoplasm Cellular component - ASPSCR1 79058 alveolar soft part sarcoma chromosome region, candidate 1 extrinsic component of membrane Cellular component - RORC 6097 RAR-related orphan receptor C sequence-specific DNA binding Molecular function - STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) nervous system development Biological process 10205054 EXOSC3 51010 exosome component 3 positive regulation of isotype switching Biological process - DDIT4 54541 DNA-damage-inducible transcript 4 neurotrophin TRK receptor signaling pathway Biological process - HNRNPA1 3178 heterogeneous nuclear ribonucleoprotein A1 RNA binding Molecular function 8521471 LRP1 4035 low density lipoprotein receptor-related protein 1 positive regulation of protein transport Biological process - KDM7A 80853 lysine (K)-specific demethylase 7A histone H4-K20 demethylation Biological process 20622853 PCM1 5108 pericentriolar material 1 intraciliary transport involved in cilium morphogenesis Biological process 24550735 TRMT112 51504 tRNA methyltransferase 11-2 homolog (S. cerevisiae) protein binding Molecular function 18539146 MAPKAPK2 9261 mitogen-activated protein kinase-activated protein kinase 2 toll-like receptor 9 signaling pathway Biological process - OR1D2 4991 olfactory receptor, family 1, subfamily D, member 2 olfactory receptor activity Molecular function 12663925 LHPP 64077 phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein homodimerization activity Molecular function 12801912 PRSS58 136541 protease, serine, 58 proteolysis Biological process - CSTL1 128817 cystatin-like 1 cysteine-type endopeptidase inhibitor activity Molecular function - CDKN1B 1027 cyclin-dependent kinase inhibitor 1B (p27, Kip1) negative regulation of kinase activity Biological process 19170105 INSR 3643 insulin receptor male sex determination Biological process - AP1S3 130340 adaptor-related protein complex 1, sigma 3 subunit regulation of defense response to virus by virus Biological process - MANF 7873 mesencephalic astrocyte-derived neurotrophic factor endoplasmic reticulum Cellular component - DPYSL3 1809 dihydropyrimidinase-like 3 response to axon injury Biological process - RUNX1T1 862 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) cytoplasm Cellular component - IMPDH1 3614 IMP (inosine 5'-monophosphate) dehydrogenase 1 GMP biosynthetic process Biological process - MLYCD 23417 malonyl-CoA decarboxylase mitochondrial matrix Cellular component - GDF2 2658 growth differentiation factor 2 positive regulation of transcription, DNA-templated Biological process 17068149 TRIM56 81844 tripartite motif containing 56 negative regulation of viral release from host cell Biological process - ZNRD1 30834 zinc ribbon domain containing 1 nucleoplasm Cellular component - EEPD1 80820 endonuclease/exonuclease/phosphatase family domain containing 1 DNA repair Biological process - COQ3 51805 coenzyme Q3 methyltransferase extrinsic component of mitochondrial inner membrane Cellular component - SRA1 10011 steroid receptor RNA activator 1 intercellular bridge Cellular component - DEFB123 245936 defensin, beta 123 extracellular region Cellular component - BRCA2 675 breast cancer 2, early onset secretory granule Cellular component 8589722 WASL 8976 Wiskott-Aldrich syndrome-like protein complex assembly Biological process 9422512 CCT5 22948 chaperonin containing TCP1, subunit 5 (epsilon) binding of sperm to zona pellucida Biological process - RBM15B 29890 RNA binding motif protein 15B nucleolus Cellular component 16129689 KLRD1 3824 killer cell lectin-like receptor subfamily D, member 1 MHC class I protein complex binding Molecular function 18448674 NYX 60506 nyctalopin molecular_function Molecular function - MAN2C1 4123 mannosidase, alpha, class 2C, member 1 alpha-mannosidase activity Molecular function - KCNC3 3748 potassium channel, voltage gated Shaw related subfamily C, member 3 regulation of ion transmembrane transport Biological process - STEAP1 26872 six transmembrane epithelial antigen of the prostate 1 metal ion binding Molecular function - TNFRSF11B 4982 tumor necrosis factor receptor superfamily, member 11b extracellular space Cellular component 15516325 POLE 5426 polymerase (DNA directed), epsilon, catalytic subunit telomere maintenance via recombination Biological process - GFPT1 2673 glutamine--fructose-6-phosphate transaminase 1 cellular response to insulin stimulus Biological process - HAUS4 54930 HAUS augmin-like complex, subunit 4 centrosome organization Biological process 19427217 HIPK2 28996 homeodomain interacting protein kinase 2 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Biological process 18974774 ULK4 54986 unc-51 like kinase 4 protein serine/threonine kinase activity Molecular function - PARP8 79668 poly (ADP-ribose) polymerase family, member 8 intracellular Cellular component - CD3E 916 CD3e molecule, epsilon (CD3-TCR complex) SH3 domain binding Molecular function 12110186 C4A 720 complement component 4A (Rodgers blood group) positive regulation of apoptotic cell clearance Biological process 19302245 KL 9365 klotho positive regulation of bone mineralization Biological process 12110410 TGM3 7053 transglutaminase 3 keratinization Biological process - SLC12A3 6559 solute carrier family 12 (sodium/chloride transporter), member 3 transport Biological process 8528245 NDUFS1 4719 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) respiratory electron transport chain Biological process - TAF1A 9015 TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa transcription from RNA polymerase I promoter Biological process - HIST1H4H 8365 histone cluster 1, H4h chromatin organization Biological process - GDPD5 81544 glycerophosphodiester phosphodiesterase domain containing 5 positive regulation of neuron differentiation Biological process - PCSK5 5125 proprotein convertase subtilisin/kexin type 5 embryonic skeletal system development Biological process 8940009 CYP2D6 1565 cytochrome P450, family 2, subfamily D, polypeptide 6 oxygen binding Molecular function - C1RL 51279 complement component 1, r subcomponent-like innate immune response Biological process - IFNGR1 3459 interferon gamma receptor 1 cytokine binding Molecular function - SKA2 348235 spindle and kinetochore associated complex subunit 2 cytosol Cellular component - SCN9A 6335 sodium channel, voltage gated, type IX alpha subunit post-embryonic development Biological process - BTG1 694 B-cell translocation gene 1, anti-proliferative protein binding Molecular function 10617598 RBL2 5934 retinoblastoma-like 2 regulation of lipid kinase activity Biological process 16286473 SMC1A 8243 structural maintenance of chromosomes 1A sister chromatid cohesion Biological process 15917200 HECW2 57520 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 cytoplasm Cellular component - CHAC2 494143 ChaC, cation transport regulator homolog 2 (E. coli) metabolic process Biological process - HNRNPA0 10949 heterogeneous nuclear ribonucleoprotein A0 inflammatory response Biological process - ZNF230 7773 zinc finger protein 230 metal ion binding Molecular function - GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A ion transmembrane transport Biological process - WISP2 8839 WNT1 inducible signaling pathway protein 2 cell adhesion Biological process - CHUK 1147 conserved helix-loop-helix ubiquitous kinase MyD88-dependent toll-like receptor signaling pathway Biological process - OR11L1 391189 olfactory receptor, family 11, subfamily L, member 1 molecular_function Molecular function - TUBB6 84617 tubulin, beta 6 class V 'de novo' posttranslational protein folding Biological process - DLK2 65989 delta-like 2 homolog (Drosophila) calcium ion binding Molecular function - NR1H4 9971 nuclear receptor subfamily 1, group H, member 4 digestive tract development Biological process - MYRFL 196446 myelin regulatory factor-like regulation of transcription, DNA-templated Biological process - TERF1 7013 telomeric repeat binding factor (NIMA-interacting) 1 positive regulation of mitotic cell cycle Biological process 9391075 CPPED1 55313 calcineurin-like phosphoesterase domain containing 1 metal ion binding Molecular function - NPHP3 27031 nephronophthisis 3 (adolescent) determination of left/right symmetry Biological process 18371931 COL9A1 1297 collagen, type IX, alpha 1 axon guidance Biological process - PPARA 5465 peroxisome proliferator-activated receptor alpha wound healing Biological process - PARK7 11315 parkinson protein 7 negative regulation of death-inducing signaling complex assembly Biological process 21785459 ARF6 382 ADP-ribosylation factor 6 regulation of Rac protein signal transduction Biological process 10036235 SH3BGRL3 83442 SH3 domain binding glutamate-rich protein like 3 regulation of actin cytoskeleton organization Biological process 24841563 MSH6 2956 mutS homolog 6 ATP binding Molecular function 15105434 SDCCAG8 10806 serologically defined colon cancer antigen 8 establishment of cell polarity Biological process - SHH 6469 sonic hedgehog intein-mediated protein splicing Biological process - ADORA1 134 adenosine A1 receptor negative regulation of leukocyte migration Biological process - ITK 3702 IL2-inducible T-cell kinase regulation of cell proliferation Biological process - CHRNB2 1141 cholinergic receptor, nicotinic, beta 2 (neuronal) acetylcholine receptor activity Molecular function 8906617 AJUBA 84962 ajuba LIM protein lamellipodium assembly Biological process - DEDD 9191 death effector domain containing nucleolus Cellular component - CST3 1471 cystatin C response to nutrient levels Biological process - PRKAG2 51422 protein kinase, AMP-activated, gamma 2 non-catalytic subunit sterol biosynthetic process Biological process 9208914 EGF 1950 epidermal growth factor neurotrophin TRK receptor signaling pathway Biological process - SRF 6722 serum response factor (c-fos serum response element-binding transcription factor) stress fiber assembly Biological process - OR4P4 81300 olfactory receptor, family 4, subfamily P, member 4 detection of chemical stimulus involved in sensory perception Biological process - PRKDC 5591 protein kinase, DNA-activated, catalytic polypeptide somitogenesis Biological process - PPP5C 5536 protein phosphatase 5, catalytic subunit phosphoprotein phosphatase activity Molecular function 9383998 GDNF 2668 glial cell derived neurotrophic factor metanephros development Biological process - MVP 9961 major vault protein ERBB signaling pathway Biological process 15133037 ABL1 25 ABL proto-oncogene 1, non-receptor tyrosine kinase negative regulation of I-kappaB kinase/NF-kappaB signaling Biological process - BAZ1A 11177 bromodomain adjacent to zinc finger domain, 1A regulation of transcription, DNA-templated Biological process 10662543 GNA12 2768 guanine nucleotide binding protein (G protein) alpha 12 response to drug Biological process - PCM1 5108 pericentriolar material 1 nuclear membrane Cellular component - RXFP3 51289 relaxin/insulin-like family peptide receptor 3 integral component of plasma membrane Cellular component 10806363 OR52A1 23538 olfactory receptor, family 52, subfamily A, member 1 G-protein coupled receptor activity Molecular function - DSN1 79980 DSN1, MIS12 kinetochore complex component protein binding Molecular function 15502821 SNX16 64089 sorting nexin 16 early endosome membrane Cellular component - CNTNAP1 8506 contactin associated protein 1 neuron projection morphogenesis Biological process - UBE2H 7328 ubiquitin-conjugating enzyme E2H ligase activity Molecular function - BCL2 596 B-cell CLL/lymphoma 2 regulation of protein homodimerization activity Biological process 9111042 GRID2IP 392862 glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein long term synaptic depression Biological process - ADCY8 114 adenylate cyclase 8 (brain) activation of protein kinase A activity Biological process - HIST2H4A 8370 histone cluster 2, H4a negative regulation of gene expression, epigenetic Biological process - TAC1 6863 tachykinin, precursor 1 positive regulation of corticosterone secretion Biological process - ATP2A1 487 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 maintenance of mitochondrion location Biological process 19061639 ZNF668 79759 zinc finger protein 668 nucleus Cellular component - CXCR2 3579 chemokine (C-X-C motif) receptor 2 integral component of plasma membrane Cellular component 10438939 DNAJC13 23317 DnaJ (Hsp40) homolog, subfamily C, member 13 WASH complex Cellular component 24643499 MZF1 7593 myeloid zinc finger 1 nucleus Cellular component - GNA12 2768 guanine nucleotide binding protein (G protein) alpha 12 adenylate cyclase-modulating G-protein coupled receptor signaling pathway Biological process - EZH2 2146 enhancer of zeste 2 polycomb repressive complex 2 subunit cytoplasm Cellular component - PLA2G5 5322 phospholipase A2, group V platelet activating factor biosynthetic process Biological process - SUOX 6821 sulfite oxidase small molecule metabolic process Biological process - EIF5A 1984 eukaryotic translation initiation factor 5A nucleus Cellular component 12210765 RAD51D 5892 RAD51 paralog D DNA binding Molecular function 9570954 CLDN11 5010 claudin 11 basal part of cell Cellular component - CYP2U1 113612 cytochrome P450, family 2, subfamily U, polypeptide 1 omega-hydroxylase P450 pathway Biological process - COL5A3 50509 collagen, type V, alpha 3 skin development Biological process 10722718 TPM2 7169 tropomyosin 2 (beta) actin binding Molecular function 17194691 CLDN5 7122 claudin 5 structural molecule activity Molecular function - EXOC4 60412 exocyst complex component 4 protein binding Molecular function 18329369 SOX8 30812 SRY (sex determining region Y)-box 8 enteric nervous system development Biological process - TCEAL3 85012 transcription elongation factor A (SII)-like 3 transcription, DNA-templated Biological process - PTPN11 5781 protein tyrosine phosphatase, non-receptor type 11 platelet-derived growth factor receptor signaling pathway Biological process - CCNT1 904 cyclin T1 viral process Biological process - ARF4 378 ADP-ribosylation factor 4 response to axon injury Biological process - ANGPT2 285 angiopoietin 2 negative regulation of angiogenesis Biological process - TMOD4 29765 tropomodulin 4 (muscle) muscle contraction Biological process 10662549 CYTH2 9266 cytohesin 2 lipid binding Molecular function - HDGF 3068 hepatoma-derived growth factor heparin binding Molecular function - FGF22 27006 fibroblast growth factor 22 cell surface Cellular component - MC1R 4157 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) positive regulation of protein kinase B signaling Biological process 18292087 COPS2 9318 COP9 signalosome subunit 2 signal transducer activity Molecular function 9535219 TGFB1 7040 transforming growth factor, beta 1 positive regulation of bone mineralization Biological process 17401695 GALNT6 11226 polypeptide N-acetylgalactosaminyltransferase 6 integral component of membrane Cellular component - PCBP2 5094 poly(rC) binding protein 2 cytosol Cellular component - GAD1 2571 glutamate decarboxylase 1 (brain, 67kDa) protein heterodimerization activity Molecular function - SPCS3 60559 signal peptidase complex subunit 3 homolog (S. cerevisiae) regulation of insulin secretion Biological process - PPM1A 5494 protein phosphatase, Mg2+/Mn2+ dependent, 1A protein dephosphorylation Biological process 18930133 TAC1 6863 tachykinin, precursor 1 cell-cell signaling Biological process 1708336 MYOD1 4654 myogenic differentiation 1 myofibril Cellular component - HES5 388585 hes family bHLH transcription factor 5 negative regulation of inner ear receptor cell differentiation Biological process - EZH2 2146 enhancer of zeste 2 polycomb repressive complex 2 subunit regulation of cell proliferation Biological process - MACF1 23499 microtubule-actin crosslinking factor 1 actin binding Molecular function 10559237 TTK 7272 TTK protein kinase spindle organization Biological process 10366450 DMP1 1758 dentin matrix acidic phosphoprotein 1 proteinaceous extracellular matrix Cellular component - SNTG1 54212 syntrophin, gamma 1 nucleus Cellular component - WDR5 11091 WD repeat domain 5 nucleus Cellular component 17500065 CCR3 1232 chemokine (C-C motif) receptor 3 chemokine-mediated signaling pathway Biological process 10415069 DPRX 503834 divergent-paired related homeobox sequence-specific DNA binding Molecular function - CYP4F2 8529 cytochrome P450, family 4, subfamily F, polypeptide 2 very long-chain fatty acid metabolic process Biological process 18433732 TNFRSF11A 8792 tumor necrosis factor receptor superfamily, member 11a, NFKB activator response to lipopolysaccharide Biological process 19940926 MYZAP 100820829 myocardial zonula adherens protein cortical actin cytoskeleton Cellular component - EPHB2 2048 EPH receptor B2 central nervous system projection neuron axonogenesis Biological process - CDH26 60437 cadherin 26 plasma membrane Cellular component - FUBP3 8939 far upstream element (FUSE) binding protein 3 protein binding Molecular function 16713569 GPBP1L1 60313 GC-rich promoter binding protein 1-like 1 transcription, DNA-templated Biological process - DCSTAMP 81501 dendrocyte expressed seven transmembrane protein endoplasmic reticulum-Golgi intermediate compartment membrane Cellular component - USP4 7375 ubiquitin specific peptidase 4 (proto-oncogene) nucleus Cellular component 16339847 ESR1 2099 estrogen receptor 1 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 12047722 MYF6 4618 myogenic factor 6 (herculin) positive regulation of myoblast fusion Biological process - CYP27B1 1594 cytochrome P450, family 27, subfamily B, polypeptide 1 calcitriol biosynthetic process from calciol Biological process 15795327 CABYR 26256 calcium binding tyrosine-(Y)-phosphorylation regulated nucleus Cellular component - TERT 7015 telomerase reverse transcriptase mitochondrial nucleoid Cellular component 21937513 DMTN 2039 dematin actin binding protein cortical cytoskeleton Cellular component - SSTR3 6753 somatostatin receptor 3 negative regulation of cell proliferation Biological process 8961277 CBLB 868 Cbl proto-oncogene B, E3 ubiquitin protein ligase calcium ion binding Molecular function - TDG 6996 thymine-DNA glycosylase transcription from RNA polymerase II promoter Biological process - LIPF 8513 lipase, gastric cellular_component Cellular component - RASAL2 9462 RAS protein activator like 2 signal transduction Biological process - RAI14 26064 retinoic acid induced 14 actin cytoskeleton Cellular component - LIMS2 55679 LIM and senescent cell antigen-like domains 2 single organismal cell-cell adhesion Biological process - EMX2 2018 empty spiracles homeobox 2 anterior/posterior pattern specification Biological process - FUT8 2530 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) cellular protein metabolic process Biological process - ACTR5 79913 ARP5 actin-related protein 5 homolog (yeast) double-strand break repair Biological process 19014934 SLC16A1 6566 solute carrier family 16 (monocarboxylate transporter), member 1 mevalonate transport Biological process 1429658 DSCR4 10281 Down syndrome critical region 4 cellular_component Cellular component - GLRA4 441509 glycine receptor, alpha 4 extracellular ligand-gated ion channel activity Molecular function - GSPT1 2935 G1 to S phase transition 1 translational termination Biological process 15326224 FGD3 89846 FYVE, RhoGEF and PH domain containing 3 small GTPase mediated signal transduction Biological process - PNKD 25953 paroxysmal nonkinesigenic dyskinesia regulation of dopamine metabolic process Biological process - KCNH2 3757 potassium channel, voltage gated eag related subfamily H, member 2 positive regulation of potassium ion transmembrane transport Biological process 7736582 OMP 4975 olfactory marker protein signal transducer activity Molecular function - OR6B2 389090 olfactory receptor, family 6, subfamily B, member 2 odorant binding Molecular function - SCYL3 57147 SCY1-like 3 (S. cerevisiae) cell migration Biological process 12651155 CRYAB 1410 crystallin, alpha B muscle organ development Biological process - OR10G3 26533 olfactory receptor, family 10, subfamily G, member 3 integral component of membrane Cellular component - HBG1 3047 hemoglobin, gamma A iron ion binding Molecular function - OR7A5 26659 olfactory receptor, family 7, subfamily A, member 5 G-protein coupled receptor activity Molecular function - SLX1A 548593 SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) protein binding Molecular function 19595721 NCKAP1 10787 NCK-associated protein 1 focal adhesion Cellular component 21423176 SLC22A16 85413 solute carrier family 22 (organic cation/carnitine transporter), member 16 organic cation transmembrane transporter activity Molecular function 15963465 TOP1 7150 topoisomerase (DNA) I circadian regulation of gene expression Biological process 22904072 CAMK1D 57118 calcium/calmodulin-dependent protein kinase ID ATP binding Molecular function - UBC 7316 ubiquitin C mitotic cell cycle Biological process - MRAS 22808 muscle RAS oncogene homolog actin cytoskeleton organization Biological process 9395237 OSBPL8 114882 oxysterol binding protein-like 8 protein localization to nuclear pore Biological process - MYO1C 4641 myosin IC stereocilium membrane Cellular component - TAOK3 51347 TAO kinase 3 cellular response to DNA damage stimulus Biological process 17396146 EEA1 8411 early endosome antigen 1 1-phosphatidylinositol binding Molecular function 11256955 TRIM8 81603 tripartite motif containing 8 cytokine-mediated signaling pathway Biological process - KLK9 284366 kallikrein-related peptidase 9 extracellular region Cellular component - DLG4 1742 discs, large homolog 4 (Drosophila) negative regulation of receptor internalization Biological process - TSHB 7252 thyroid stimulating hormone, beta peptide hormone processing Biological process - COL4A3BP 10087 collagen, type IV, alpha 3 (Goodpasture antigen) binding protein sphingolipid biosynthetic process Biological process - RYR2 6262 ryanodine receptor 2 (cardiac) cytosol Cellular component - TCF3 6929 transcription factor 3 positive regulation of muscle cell differentiation Biological process - ARCN1 372 archain 1 poly(A) RNA binding Molecular function 22658674 KCNJ4 3761 potassium channel, inwardly rectifying subfamily J, member 4 plasma membrane Cellular component - PARP1 142 poly (ADP-ribose) polymerase 1 poly(A) RNA binding Molecular function 22658674 VN1R2 317701 vomeronasal 1 receptor 2 response to pheromone Biological process - ERBB4 2066 erb-b2 receptor tyrosine kinase 4 protein autophosphorylation Biological process 18334220 P4HB 5034 prolyl 4-hydroxylase, beta polypeptide cell redox homeostasis Biological process - SORT1 6272 sortilin 1 response to insulin Biological process 15992544 MDFI 4188 MyoD family inhibitor embryonic skeletal system morphogenesis Biological process - STX18 53407 syntaxin 18 Golgi membrane Cellular component - COX7A2L 9167 cytochrome c oxidase subunit VIIa polypeptide 2 like gene expression Biological process - SLC12A1 6557 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 apical plasma membrane Cellular component - SMARCD1 6602 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 nervous system development Biological process - BPGM 669 2,3-bisphosphoglycerate mutase dephosphorylation Biological process - RBM14 10432 RNA binding motif protein 14 RNA polymerase II transcription cofactor activity Molecular function 11443112 GNB2 2783 guanine nucleotide binding protein (G protein), beta polypeptide 2 plasma membrane Cellular component - SPO11 23626 SPO11 meiotic protein covalently bound to DSB ovarian follicle development Biological process - GALNT1 2589 polypeptide N-acetylgalactosaminyltransferase 1 protein O-linked glycosylation via serine Biological process 9295285 SLC16A5 9121 solute carrier family 16 (monocarboxylate transporter), member 5 integral component of plasma membrane Cellular component 9425115 CCL21 6366 chemokine (C-C motif) ligand 21 chemokine receptor binding Molecular function 23341447 GPR42 2866 G protein-coupled receptor 42 (gene/pseudogene) G-protein coupled receptor activity Molecular function 19630535 PPCDC 60490 phosphopantothenoylcysteine decarboxylase phosphopantothenoylcysteine decarboxylase activity Molecular function - MYOC 4653 myocilin, trabecular meshwork inducible glucocorticoid response node of Ranvier Cellular component - ARV1 64801 ARV1 homolog (S. cerevisiae) sphingolipid metabolic process Biological process - MX2 4600 MX dynamin-like GTPase 2 nuclear pore Cellular component 15184662 ADAM18 8749 ADAM metallopeptidase domain 18 integral component of membrane Cellular component - CX3CL1 6376 chemokine (C-X3-C motif) ligand 1 positive regulation of transforming growth factor beta1 production Biological process - MS4A2 2206 membrane-spanning 4-domains, subfamily A, member 2 activation of phospholipase C activity Biological process - CSF1R 1436 colony stimulating factor 1 receptor positive regulation of chemokine secretion Biological process 20829061 ENO4 387712 enolase family member 4 glycolytic process Biological process - MDN1 23195 MDN1, midasin homolog (yeast) cytoplasm Cellular component - HSD17B4 3295 hydroxysteroid (17-beta) dehydrogenase 4 Sertoli cell development Biological process - POLR3A 11128 polymerase (RNA) III (DNA directed) polypeptide A, 155kDa gene expression Biological process - PPARD 5467 peroxisome proliferator-activated receptor delta negative regulation of smooth muscle cell proliferation Biological process - DHX58 79132 DEXH (Asp-Glu-X-His) box polypeptide 58 viral process Biological process - ZNF662 389114 zinc finger protein 662 transcription, DNA-templated Biological process - GHSR 2693 growth hormone secretagogue receptor cellular response to insulin stimulus Biological process - RPL12 6136 ribosomal protein L12 translational termination Biological process - EIF4A1 1973 eukaryotic translation initiation factor 4A1 double-stranded RNA binding Molecular function 21266579 VIPAS39 63894 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog protein binding Molecular function 16189514 NDUFB7 4713 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa respiratory electron transport chain Biological process - MARCO 8685 macrophage receptor with collagenous structure cell surface receptor signaling pathway Biological process 9468508 SGK1 6446 serum/glucocorticoid regulated kinase 1 protein serine/threonine/tyrosine kinase activity Molecular function 22797923 TCEANC2 127428 transcription elongation factor A (SII) N-terminal and central domain containing 2 nucleus Cellular component - IRF7 3665 interferon regulatory factor 7 protein binding Molecular function 11943871 UTY 7404 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked histone demethylase activity (H3-K27 specific) Molecular function - ABHD14A 25864 abhydrolase domain containing 14A cytoplasm Cellular component - FTCD 10841 formimidoyltransferase cyclodeaminase cytoplasm Cellular component 10029623 GCG 2641 glucagon response to starvation Biological process - MDH1 4190 malate dehydrogenase 1, NAD (soluble) NAD binding Molecular function - SMARCE1 6605 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 ATP-dependent chromatin remodeling Biological process 16217013 RAD50 10111 RAD50 homolog (S. cerevisiae) ATP binding Molecular function - RBBP4 5928 retinoblastoma binding protein 4 CENP-A containing nucleosome assembly Biological process - SLC39A5 283375 solute carrier family 39 (zinc transporter), member 5 neural precursor cell proliferation Biological process - NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 positive regulation of transcription from RNA polymerase II promoter Biological process - HYAL2 8692 hyaluronoglucosaminidase 2 plasma membrane Cellular component - UGT8 7368 UDP glycosyltransferase 8 cytoskeleton organization Biological process - HTRA4 203100 HtrA serine peptidase 4 negative regulation of transforming growth factor beta receptor signaling pathway Biological process - MAP3K15 389840 mitogen-activated protein kinase kinase kinase 15 ATP binding Molecular function - KATNB1 10300 katanin p80 (WD repeat containing) subunit B 1 cell division Biological process - FOXA2 3170 forkhead box A2 lung epithelial cell differentiation Biological process - GPI 2821 glucose-6-phosphate isomerase learning or memory Biological process - NCOA3 8202 nuclear receptor coactivator 3 cellular response to hormone stimulus Biological process - HOXA1 3198 homeobox A1 central nervous system neuron differentiation Biological process - AXL 558 AXL receptor tyrosine kinase negative regulation of lymphocyte activation Biological process - SLC12A9 56996 solute carrier family 12, member 9 integral component of membrane Cellular component - TIMM44 10469 translocase of inner mitochondrial membrane 44 homolog (yeast) cellular protein metabolic process Biological process - CNKSR2 22866 connector enhancer of kinase suppressor of Ras 2 extracellular exosome Cellular component 19056867 GSTO1 9446 glutathione S-transferase omega 1 cellular response to arsenic-containing substance Biological process 11511179 RIT1 6016 Ras-like without CAAX 1 signal transduction Biological process 8918462 FOXC1 2296 forkhead box C1 cytoplasm Cellular component - NPHP4 261734 nephronophthisis 4 ribbon synapse Cellular component - CSTB 1476 cystatin B (stefin B) extracellular exosome Cellular component 19056867 RUVBL2 10856 RuvB-like AAA ATPase 2 DNA repair Biological process - RABIF 5877 RAB interacting factor protein transport Biological process - FNTA 2339 farnesyltransferase, CAAX box, alpha protein farnesylation Biological process 16893176 ITGAD 3681 integrin, alpha D extracellular matrix organization Biological process - VSIG4 11326 V-set and immunoglobulin domain containing 4 protein binding Molecular function 16530040 STS 412 steroid sulfatase (microsomal), isozyme S integral component of membrane Cellular component - DNM1L 10059 dynamin 1-like intracellular membrane-bounded organelle Cellular component - PIK3CA 5290 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha phospholipid metabolic process Biological process - FGD2 221472 FYVE, RhoGEF and PH domain containing 2 cytoplasm Cellular component - SPR 6697 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) aldo-keto reductase (NADP) activity Molecular function 1883349 FZD8 8325 frizzled class receptor 8 integral component of membrane Cellular component 11295046 COL5A2 1290 collagen, type V, alpha 2 skin development Biological process - GAS2L1 10634 growth arrest-specific 2 like 1 microtubule Cellular component 12584248 OR10D4P 390266 olfactory receptor, family 10, subfamily D, member 4 pseudogene G-protein coupled receptor signaling pathway Biological process - ZNF594 84622 zinc finger protein 594 nucleus Cellular component - GLRB 2743 glycine receptor, beta extracellular-glycine-gated ion channel activity Molecular function 11929858 HILPDA 29923 hypoxia inducible lipid droplet-associated lipid particle Cellular component 20624928 CCR10 2826 chemokine (C-C motif) receptor 10 G-protein coupled receptor activity Molecular function 7851889 ARNT 405 aryl hydrocarbon receptor nuclear translocator RNA polymerase II transcription factor complex Cellular component 7539918 TIMP2 7077 TIMP metallopeptidase inhibitor 2 extracellular matrix organization Biological process - STX4 6810 syntaxin 4 vacuole Cellular component 16339081 CDKN2A 1029 cyclin-dependent kinase inhibitor 2A activation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 12082630 NRG3 10718 neuregulin 3 receptor binding Molecular function - NAA15 80155 N(alpha)-acetyltransferase 15, NatA auxiliary subunit protein binding Molecular function 12145306 RIPK4 54101 receptor-interacting serine-threonine kinase 4 morphogenesis of an epithelium Biological process 22197488 ITGAM 3684 integrin, alpha M (complement component 3 receptor 3 subunit) extracellular exosome Cellular component 23376485 CD36 948 CD36 molecule (thrombospondin receptor) negative regulation of transcription factor import into nucleus Biological process - IL5 3567 interleukin 5 extracellular region Cellular component - PDIA3 2923 protein disulfide isomerase family A, member 3 cell surface Cellular component 19995400 GBA 2629 glucosidase, beta, acid glycosphingolipid metabolic process Biological process - OR2L8 391190 olfactory receptor, family 2, subfamily L, member 8 (gene/pseudogene) G-protein coupled receptor signaling pathway Biological process - MRPL37 51253 mitochondrial ribosomal protein L37 structural constituent of ribosome Molecular function 11543634 DPP4 1803 dipeptidyl-peptidase 4 integral component of membrane Cellular component - GNG11 2791 guanine nucleotide binding protein (G protein), gamma 11 G-protein coupled receptor signaling pathway Biological process - COASY 80347 CoA synthase protein binding Molecular function 22982864 PRLHR 2834 prolactin releasing hormone receptor G-protein coupled receptor signaling pathway Biological process 8666380 IFNG 3458 interferon, gamma defense response to bacterium Biological process - IQCB1 9657 IQ motif containing B1 maintenance of organ identity Biological process 15723066 CD37 951 CD37 molecule membrane Cellular component 19946888 OR6C70 390327 olfactory receptor, family 6, subfamily C, member 70 plasma membrane Cellular component - OLIG2 10215 oligodendrocyte lineage transcription factor 2 positive regulation of oligodendrocyte differentiation Biological process - CELF3 11189 CUGBP, Elav-like family member 3 sperm motility Biological process - RAB3B 5865 RAB3B, member RAS oncogene family GDP binding Molecular function 22321395 CCR7 1236 chemokine (C-C motif) receptor 7 immune response Biological process - CYC1 1537 cytochrome c-1 heme binding Molecular function - COG2 22796 component of oligomeric golgi complex 2 intra-Golgi vesicle-mediated transport Biological process 7962052 KAT5 10524 K(lysine) acetyltransferase 5 cytosol Cellular component - CD55 1604 CD55 molecule, decay accelerating factor for complement (Cromer blood group) plasma membrane Cellular component - MEFV 4210 Mediterranean fever nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway Biological process - TK2 7084 thymidine kinase 2, mitochondrial deoxycytidine kinase activity Molecular function - AMN 81693 amnion associated transmembrane protein apical plasma membrane Cellular component 14576052 CYC1 1537 cytochrome c-1 metal ion binding Molecular function - HMGB2 3148 high mobility group box 2 chemoattractant activity Molecular function 19811285 RP1L1 94137 retinitis pigmentosa 1-like 1 extracellular exosome Cellular component 23376485 GABARAPL1 23710 GABA(A) receptor-associated protein like 1 autophagosome membrane Cellular component - NUDC 10726 nudC nuclear distribution protein cell division Biological process - SYTL2 54843 synaptotagmin-like 2 extrinsic component of plasma membrane Cellular component - GZF1 64412 GDNF-inducible zinc finger protein 1 cytoplasm Cellular component - DDX47 51202 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 ATP-dependent RNA helicase activity Molecular function - NUDT16 131870 nudix (nucleoside diphosphate linked moiety X)-type motif 16 inosine-diphosphatase activity Molecular function - ATM 472 ATM serine/threonine kinase peptidyl-serine phosphorylation Biological process 9733515 VPS36 51028 vacuolar protein sorting 36 homolog (S. cerevisiae) late endosome membrane Cellular component 17010938 NUP160 23279 nucleoporin 160kDa cytokine-mediated signaling pathway Biological process - RIC8B 55188 RIC8 guanine nucleotide exchange factor B cell cortex Cellular component - PSMF1 9491 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) negative regulation of proteasomal protein catabolic process Biological process 10764772 PLK4 10733 polo-like kinase 4 centrosome Cellular component 21399614 HLA-DRA 3122 major histocompatibility complex, class II, DR alpha T cell costimulation Biological process - HYAL2 8692 hyaluronoglucosaminidase 2 cellular response to UV-B Biological process 21699545 PTPN11 5781 protein tyrosine phosphatase, non-receptor type 11 megakaryocyte development Biological process - COL5A3 50509 collagen, type V, alpha 3 collagen fibril organization Biological process 10722718 DTL 51514 denticleless E3 ubiquitin protein ligase homolog (Drosophila) protein polyubiquitination Biological process 17085480 DPYS 1807 dihydropyrimidinase small molecule metabolic process Biological process - NOS2 4843 nitric oxide synthase 2, inducible defense response to Gram-negative bacterium Biological process 18390757 PDLIM3 27295 PDZ and LIM domain 3 actin cytoskeleton Cellular component - ATG5 9474 autophagy related 5 vasodilation Biological process - STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) acute-phase response Biological process - RNPC3 55599 RNA-binding region (RNP1, RRM) containing 3 nucleotide binding Molecular function - SOD1 6647 superoxide dismutase 1, soluble superoxide dismutase activity Molecular function - PRMT7 54496 protein arginine methyltransferase 7 regulation of gene expression by genetic imprinting Biological process - ST6GAL2 84620 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 Golgi membrane Cellular component - MAP1S 55201 microtubule-associated protein 1S nucleolus Cellular component - TBC1D17 79735 TBC1 domain family, member 17 cytosol Cellular component 17562788 ITCH 83737 itchy E3 ubiquitin protein ligase protein K29-linked ubiquitination Biological process 17028573 RC3H1 149041 ring finger and CCCH-type domains 1 lymph node development Biological process - CCDC53 51019 coiled-coil domain containing 53 intracellular membrane-bounded organelle Cellular component - STAT5A 6776 signal transducer and activator of transcription 5A valine metabolic process Biological process - TMEM8C 389827 transmembrane protein 8C plasma membrane Cellular component - SPHK1 8877 sphingosine kinase 1 sphingosine metabolic process Biological process 20577214 GABRA3 2556 gamma-aminobutyric acid (GABA) A receptor, alpha 3 chloride channel complex Cellular component - ARAP3 64411 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 negative regulation of cell migration Biological process - AURKB 9212 aurora kinase B condensed nuclear chromosome, centromeric region Cellular component 18195732 NDOR1 27158 NADPH dependent diflavin oxidoreductase 1 small molecule metabolic process Biological process - SLC6A4 6532 solute carrier family 6 (neurotransmitter transporter), member 4 response to hypoxia Biological process - SAG 6295 S-antigen; retina and pineal gland (arrestin) photoreceptor inner segment Cellular component - RNF4 6047 ring finger protein 4 transcription, DNA-templated Biological process - DESI2 51029 desumoylating isopeptidase 2 proteolysis Biological process - AXIN2 8313 axin 2 regulation of transcription, DNA-templated Biological process - CXCL1 2919 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) cell chemotaxis Biological process 10820279 DENND1A 57706 DENN/MADD domain containing 1A presynaptic membrane Cellular component - AMACR 23600 alpha-methylacyl-CoA racemase alpha-methylacyl-CoA racemase activity Molecular function 10655068 CYP21A2 1589 cytochrome P450, family 21, subfamily A, polypeptide 2 oxidation-reduction process Biological process - ZNF148 7707 zinc finger protein 148 transcription from RNA polymerase II promoter Biological process 9685330 TUBB3 10381 tubulin, beta 3 class III peptide binding Molecular function - NR5A1 2516 nuclear receptor subfamily 5, group A, member 1 intracellular receptor signaling pathway Biological process 8205615 CDK5RAP3 80279 CDK5 regulatory subunit associated protein 3 negative regulation of cellular protein catabolic process Biological process 16173922 PSMD13 5719 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 proteasome regulatory particle Cellular component - SPO11 23626 SPO11 meiotic protein covalently bound to DSB spermatid development Biological process - TMEM39A 55254 transmembrane protein 39A positive regulation of defense response to virus by host Biological process 22020285 CNOT2 4848 CCR4-NOT transcription complex, subunit 2 positive regulation of cytoplasmic mRNA processing body assembly Biological process 21299754 OR4K15 81127 olfactory receptor, family 4, subfamily K, member 15 olfactory receptor activity Molecular function - RASIP1 54922 Ras interacting protein 1 signal transduction Biological process - TMEM64 169200 transmembrane protein 64 cytosolic calcium ion homeostasis Biological process - NMNAT1 64802 nicotinamide nucleotide adenylyltransferase 1 nicotinamide-nucleotide adenylyltransferase activity Molecular function - HLA-DMA 3108 major histocompatibility complex, class II, DM alpha inner ear development Biological process - PIK3R1 5295 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) phosphatidylinositol 3-kinase complex, class IA Cellular component - RET 5979 ret proto-oncogene protein binding Molecular function 11536047 RYR1 6261 ryanodine receptor 1 (skeletal) I band Cellular component 11206130 TCEAL6 158931 transcription elongation factor A (SII)-like 6 nucleus Cellular component - CACNA2D1 781 calcium channel, voltage-dependent, alpha 2/delta subunit 1 regulation of calcium ion transport Biological process 1309651 TBX10 347853 T-box 10 nucleus Cellular component - NOD2 64127 nucleotide-binding oligomerization domain containing 2 positive regulation of interleukin-1 beta production Biological process 21040358 CRY2 1408 cryptochrome circadian clock 2 negative regulation of transcription from RNA polymerase II promoter Biological process 12397359 NOD2 64127 nucleotide-binding oligomerization domain containing 2 toll-like receptor TLR1:TLR2 signaling pathway Biological process - GNA13 10672 guanine nucleotide binding protein (G protein), alpha 13 Rho protein signal transduction Biological process - DNAJC7 7266 DnaJ (Hsp40) homolog, subfamily C, member 7 cellular response to heat Biological process - INA 9118 internexin neuronal intermediate filament protein, alpha structural constituent of cytoskeleton Molecular function 7769995 UBE2B 7320 ubiquitin-conjugating enzyme E2B ubiquitin protein ligase activity Molecular function - HES3 390992 hes family bHLH transcription factor 3 midbrain-hindbrain boundary morphogenesis Biological process - MIA2 117153 melanoma inhibitory activity 2 cholesterol homeostasis Biological process - SIN3B 23309 SIN3 transcription regulator family member B negative regulation of transcription from RNA polymerase II promoter Biological process - DCTN1 1639 dynactin 1 microtubule Cellular component 21525035 KLF17 128209 Kruppel-like factor 17 transcription regulatory region DNA binding Molecular function - AQP1 358 aquaporin 1 (Colton blood group) cellular response to retinoic acid Biological process 12051745 SOHLH2 54937 spermatogenesis and oogenesis specific basic helix-loop-helix 2 oogenesis Biological process - YWHAH 7533 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway Biological process - SLC17A9 63910 solute carrier family 17 (vesicular nucleotide transporter), member 9 transmembrane transporter activity Molecular function - DBH 1621 dopamine beta-hydroxylase (dopamine beta-monooxygenase) secretory granule lumen Cellular component - FKBP4 2288 FK506 binding protein 4, 59kDa poly(A) RNA binding Molecular function 22658674 RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand Biological process - MDM4 4194 MDM4, p53 regulator cellular response to hypoxia Biological process 20810912 RNF38 152006 ring finger protein 38 protein ubiquitination Biological process - PARK2 5071 parkin RBR E3 ubiquitin protein ligase cellular protein catabolic process Biological process 21376232 TREH 11181 trehalase (brush-border membrane glycoprotein) plasma membrane Cellular component 9427547 KCNC2 3747 potassium channel, voltage gated Shaw related subfamily C, member 2 synaptic transmission Biological process - PLSCR1 5359 phospholipid scramblase 1 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 16091359 UBE2M 9040 ubiquitin-conjugating enzyme E2M ubiquitin-protein transferase activity Molecular function 9694792 RPS5 6193 ribosomal protein S5 cytosol Cellular component - LMLN 89782 leishmanolysin-like (metallopeptidase M8 family) focal adhesion Cellular component - ABHD8 79575 abhydrolase domain containing 8 extracellular exosome Cellular component 18570454 STK3 6788 serine/threonine kinase 3 positive regulation of protein binding Biological process 22292086 NUP43 348995 nucleoporin 43kDa carbohydrate metabolic process Biological process - KLF4 9314 Kruppel-like factor 4 (gut) mesodermal cell fate determination Biological process 8940147 ITGA2 3673 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) cellular response to hormone stimulus Biological process - ENSA 2029 endosulfine alpha protein phosphatase inhibitor activity Molecular function - ATP9A 10079 ATPase, class II, type 9A early endosome Cellular component 21914794 PRG3 10394 proteoglycan 3 immune response Biological process - KDM5B 10765 lysine (K)-specific demethylase 5B transcription corepressor activity Molecular function 12657635 OR1S2 219958 olfactory receptor, family 1, subfamily S, member 2 olfactory receptor activity Molecular function - BEX2 84707 brain expressed X-linked 2 nucleus Cellular component - CDK1 983 cyclin-dependent kinase 1 innate immune response Biological process - SPTBN1 6711 spectrin, beta, non-erythrocytic 1 GTPase binding Molecular function 24337748 CRBN 51185 cereblon negative regulation of protein homooligomerization Biological process - VIPAS39 63894 VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog HOPS complex Cellular component 19109425 TAPBP 6892 TAP binding protein (tapasin) antigen processing and presentation of endogenous peptide antigen via MHC class I Biological process - ADAMTS13 11093 ADAM metallopeptidase with thrombospondin type 1 motif, 13 metalloendopeptidase activity Molecular function - SERPING1 710 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 aging Biological process - CASP3 836 caspase 3, apoptosis-related cysteine peptidase cellular response to DNA damage stimulus Biological process - ABCA1 19 ATP-binding cassette, sub-family A (ABC1), member 1 transmembrane transport Biological process - PLEKHA4 57664 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 1-phosphatidylinositol binding Molecular function 11001876 GHRHR 2692 growth hormone releasing hormone receptor growth factor binding Molecular function 7680413 SOST 50964 sclerostin negative regulation of ossification Biological process 11181578 FUT10 84750 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) fertilization Biological process 11698403 UBE2L6 9246 ubiquitin-conjugating enzyme E2L 6 negative regulation of type I interferon production Biological process - FBXL5 26234 F-box and leucine-rich repeat protein 5 ubiquitin ligase complex Cellular component 10531035 OVOL2 58495 ovo-like zinc finger 2 neural fold formation Biological process - DDIT3 1649 DNA-damage-inducible transcript 3 protein homodimerization activity Molecular function - OR10G4 390264 olfactory receptor, family 10, subfamily G, member 4 integral component of membrane Cellular component - ZNF473 25888 zinc finger protein 473 mRNA 3'-end processing Biological process - MMS22L 253714 MMS22-like, DNA repair protein double-strand break repair via homologous recombination Biological process 21055983 WNT5A 7474 wingless-type MMTV integration site family, member 5A positive regulation of protein catabolic process Biological process 12952940 NKX2-5 1482 NK2 homeobox 5 negative regulation of myotube differentiation Biological process 15653675 SFN 2810 stratifin extracellular exosome Cellular component 19056867 TTC1 7265 tetratricopeptide repeat domain 1 protein folding Biological process 8836031 GABRR2 2570 gamma-aminobutyric acid (GABA) A receptor, rho 2 signal transduction Biological process 1315307 ZXDC 79364 ZXD family zinc finger C sequence-specific DNA binding transcription factor activity Molecular function 17493635 NCOA3 8202 nuclear receptor coactivator 3 positive regulation of transcription, DNA-templated Biological process 15572661 ASCL1 429 achaete-scute family bHLH transcription factor 1 chromatin binding Molecular function - SHH 6469 sonic hedgehog positive regulation of kidney smooth muscle cell differentiation Biological process - CENPV 201161 centromere protein V pericentric heterochromatin assembly Biological process 18772885 KLF2 10365 Kruppel-like factor 2 Type I pneumocyte differentiation Biological process - TRIM28 10155 tripartite motif containing 28 negative regulation of viral release from host cell Biological process 18248090 FGD2 221472 FYVE, RhoGEF and PH domain containing 2 guanyl-nucleotide exchange factor activity Molecular function - RSPH4A 345895 radial spoke head 4 homolog A (Chlamydomonas) nucleoplasm Cellular component - BACE1 23621 beta-site APP-cleaving enzyme 1 peptidase activity Molecular function 8562317 SALL1 6299 spalt-like transcription factor 1 sequence-specific DNA binding transcription factor activity Molecular function 9425907 PPP4R2 151987 protein phosphatase 4, regulatory subunit 2 nucleoplasm Cellular component - AHR 196 aryl hydrocarbon receptor ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function 10395741 ERCC2 2068 excision repair cross-complementation group 2 extracellular matrix organization Biological process - PURB 5814 purine-rich element binding protein B transcription, DNA-templated Biological process - IRF2 3660 interferon regulatory factor 2 interferon-gamma-mediated signaling pathway Biological process - RARA 5914 retinoic acid receptor, alpha signal transduction Biological process 2825025 FGD5 152273 FYVE, RhoGEF and PH domain containing 5 early endosome Cellular component - ARID5B 84159 AT rich interactive domain 5B (MRF1-like) palate development Biological process - PSEN1 5663 presenilin 1 regulation of protein binding Biological process - PAPOLA 10914 poly(A) polymerase alpha ATP binding Molecular function - MAP4K1 11184 mitogen-activated protein kinase kinase kinase kinase 1 peptidyl-serine phosphorylation Biological process 11053428 SLC6A8 6535 solute carrier family 6 (neurotransmitter transporter), member 8 creatine transport Biological process 8661037 POP1 10940 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) tRNA catabolic process Biological process 8918471 TRIO 7204 trio Rho guanine nucleotide exchange factor cytosol Cellular component - INHA 3623 inhibin, alpha skeletal system development Biological process 10865214 PIEZO1 9780 piezo-type mechanosensitive ion channel component 1 mechanically-gated ion channel activity Molecular function - PYCARD 29108 PYD and CARD domain containing tumor necrosis factor-mediated signaling pathway Biological process 12656673 SHB 6461 Src homology 2 domain containing adaptor protein B SH3/SH2 adaptor activity Molecular function 8302579 HSP90AA1 3320 heat shock protein 90kDa alpha (cytosolic), class A member 1 dATP binding Molecular function - AGRN 375790 agrin heparan sulfate proteoglycan binding Molecular function - ZFP69B 65243 ZFP69 zinc finger protein B sequence-specific DNA binding transcription factor activity Molecular function - TENM1 10178 teneurin transmembrane protein 1 neuropeptide signaling pathway Biological process - PABPN1 8106 poly(A) binding protein, nuclear 1 poly(A)+ mRNA export from nucleus Biological process 19364924 CREBRF 153222 CREB3 regulatory factor positive regulation of intracellular transport Biological process 18391022 PURA 5813 purine-rich element binding protein A positive regulation of cell proliferation Biological process - ADAM10 102 ADAM metallopeptidase domain 10 protein homodimerization activity Molecular function - PICK1 9463 protein interacting with PRKCA 1 cytoskeleton Cellular component - IGBP1 3476 immunoglobulin (CD79A) binding protein 1 protein phosphatase type 2A regulator activity Molecular function 9647778 PPARD 5467 peroxisome proliferator-activated receptor delta response to activity Biological process - PDK3 5165 pyruvate dehydrogenase kinase, isozyme 3 glucose metabolic process Biological process - HSF4 3299 heat shock transcription factor 4 protein phosphatase binding Molecular function 16581800 GATA4 2626 GATA binding protein 4 ventricular cardiac muscle tissue development Biological process - MTPN 136319 myotrophin nucleus Cellular component - NOTCH1 4851 notch 1 protein binding Molecular function 10713164 GATA6 2627 GATA binding protein 6 positive regulation of cardiac muscle cell proliferation Biological process - HAX1 10456 HCLS1 associated protein X-1 nuclear membrane Cellular component - PAWR 5074 PRKC, apoptosis, WT1, regulator apoptotic signaling pathway Biological process - WNT10A 80326 wingless-type MMTV integration site family, member 10A regulation of odontogenesis of dentin-containing tooth Biological process - PCDHGB4 8641 protocadherin gamma subfamily B, 4 cell adhesion Biological process 9199196 CDC16 8881 cell division cycle 16 spindle Cellular component 7736578 AQP2 359 aquaporin 2 (collecting duct) cellular response to mercury ion Biological process 8584435 ACVR2B 93 activin A receptor, type IIB positive regulation of bone mineralization Biological process 18436533 PKD2 5311 polycystic kidney disease 2 (autosomal dominant) calcium ion transport Biological process - TAB3 257397 TGF-beta activated kinase 1/MAP3K7 binding protein 3 toll-like receptor 2 signaling pathway Biological process - BCL2L14 79370 BCL2-like 14 (apoptosis facilitator) cytoplasm Cellular component - MAP3K14 9020 mitogen-activated protein kinase kinase kinase 14 stress-activated protein kinase signaling cascade Biological process - EIF4H 7458 eukaryotic translation initiation factor 4H RNA binding Molecular function 8812460 CAMKK1 84254 calcium/calmodulin-dependent protein kinase kinase 1, alpha protein binding Molecular function 18242179 NME4 4833 NME/NM23 nucleoside diphosphate kinase 4 cytosol Cellular component - LDHB 3945 lactate dehydrogenase B cytosol Cellular component - HHIP 64399 hedgehog interacting protein negative regulation of smoothened signaling pathway Biological process 11435703 SLC11A2 4891 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 paraferritin complex Cellular component 11842004 ADAMTS4 9507 ADAM metallopeptidase with thrombospondin type 1 motif, 4 protein binding Molecular function 18718938 TCAF1 9747 TRPM8 channel-associated factor 1 ion channel binding Molecular function 25559186 LPPR2 64748 lipid phosphate phosphatase-related protein type 2 dephosphorylation Biological process - FLNA 2316 filamin A, alpha extracellular exosome Cellular component 19056867 ADCY5 111 adenylate cyclase 5 activation of phospholipase C activity Biological process - FXYD1 5348 FXYD domain containing ion transport regulator 1 plasma membrane Cellular component - RAG1 5896 recombination activating gene 1 protein homodimerization activity Molecular function - COL19A1 1310 collagen, type XIX, alpha 1 skeletal system development Biological process 9143499 USP1 7398 ubiquitin specific peptidase 1 regulation of DNA repair Biological process 18082604 ENTPD8 377841 ectonucleoside triphosphate diphosphohydrolase 8 nucleoside diphosphate biosynthetic process Biological process - PKHD1 5314 polycystic kidney and hepatic disease 1 (autosomal recessive) single organismal cell-cell adhesion Biological process - LUC7L 55692 LUC7-like (S. cerevisiae) mRNA splice site selection Biological process - UBE2D1 7321 ubiquitin-conjugating enzyme E2D 1 regulation of transcription from RNA polymerase II promoter in response to hypoxia Biological process - CDH5 1003 cadherin 5, type 2 (vascular endothelium) cell-cell junction organization Biological process - ACTN4 81 actinin, alpha 4 protein localization to bicellular tight junction Biological process - MST1R 4486 macrophage stimulating 1 receptor defense response Biological process 9045873 DOT1L 84444 DOT1-like histone H3K79 methyltransferase histone methyltransferase activity (H3-K79 specific) Molecular function - GSTK1 373156 glutathione S-transferase kappa 1 mitochondrial inner membrane Cellular component - UGT1A10 54575 UDP glucuronosyltransferase 1 family, polypeptide A10 protein heterodimerization activity Molecular function 20610558 F9 2158 coagulation factor IX blood coagulation, intrinsic pathway Biological process - SERPINB3 6317 serpin peptidase inhibitor, clade B (ovalbumin), member 3 viral entry into host cell Biological process 12975381 KIAA0101 9768 KIAA0101 centrosome organization Biological process 21673012 BMP8A 353500 bone morphogenetic protein 8a positive regulation of pathway-restricted SMAD protein phosphorylation Biological process - CST11 140880 cystatin 11 negative regulation of endopeptidase activity Biological process - ZMYM4 9202 zinc finger, MYM-type 4 nucleus Cellular component - ZFP36 7538 ZFP36 ring finger protein 3'-UTR-mediated mRNA stabilization Biological process 15014438 DDX20 11218 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 cytoplasm Cellular component - COL1A1 1277 collagen, type I, alpha 1 extracellular matrix Cellular component 22261194 TNFRSF12A 51330 tumor necrosis factor receptor superfamily, member 12A substrate-dependent cell migration, cell attachment to substrate Biological process - SOAT1 6646 sterol O-acyltransferase 1 cholesterol efflux Biological process 15308631 HNRNPCL3 649330 heterogeneous nuclear ribonucleoprotein C-like 3 nucleus Cellular component - CTCF 10664 CCCTC-binding factor (zinc finger protein) RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 8649389 SERPINE1 5054 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 positive regulation of interleukin-8 production Biological process 19916862 XPA 7507 xeroderma pigmentosum, complementation group A Golgi apparatus Cellular component - GRIK2 2898 glutamate receptor, ionotropic, kainate 2 presynaptic membrane Cellular component - TAS2R7 50837 taste receptor, type 2, member 7 integral component of membrane Cellular component 20022913 HTR2B 3357 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled serotonin binding Molecular function 15625277 TFF3 7033 trefoil factor 3 (intestinal) molecular_function Molecular function - OR5M8 219484 olfactory receptor, family 5, subfamily M, member 8 plasma membrane Cellular component - FXYD3 5349 FXYD domain containing ion transport regulator 3 extracellular exosome Cellular component 19199708 TNFRSF10A 8797 tumor necrosis factor receptor superfamily, member 10a protease binding Molecular function 21785459 PCSK9 255738 proprotein convertase subtilisin/kexin type 9 very-low-density lipoprotein particle receptor binding Molecular function 18039658 ANXA13 312 annexin A13 calcium-dependent phospholipid binding Molecular function - HTT 3064 huntingtin negative regulation of extrinsic apoptotic signaling pathway Biological process 19240112 TBCE 6905 tubulin folding cofactor E protein folding Biological process 8706133 ACTR3 10096 ARP3 actin-related protein 3 homolog (yeast) focal adhesion Cellular component 21423176 NID1 4811 nidogen 1 positive regulation of cell-substrate adhesion Biological process - DAP 1611 death-associated protein apoptotic process Biological process 7828849 ZP1 22917 zona pellucida glycoprotein 1 (sperm receptor) secretory granule Cellular component - ZNF843 283933 zinc finger protein 843 protein binding Molecular function 22939624 OXT 5020 oxytocin/neurophysin I prepropeptide positive regulation of synaptic transmission Biological process - MSX2 4488 msh homeobox 2 signal transduction involved in regulation of gene expression Biological process - FAT1 2195 FAT atypical cadherin 1 cell-cell signaling Biological process 8586420 GALP 85569 galanin-like peptide regulation of appetite Biological process - JUN 3725 jun proto-oncogene poly(A) RNA binding Molecular function 22681889 PARK2 5071 parkin RBR E3 ubiquitin protein ligase aggresome Cellular component 14645198 PEX5 5830 peroxisomal biogenesis factor 5 peroxisome targeting sequence binding Molecular function 18346465 HLTF 6596 helicase-like transcription factor ubiquitin protein ligase activity Molecular function - LMBR1L 55716 limb development membrane protein 1-like integral component of membrane Cellular component - CDC42BPB 9578 CDC42 binding protein kinase beta (DMPK-like) cell-cell junction Cellular component - AXIN1 8312 axin 1 negative regulation of fat cell differentiation Biological process - RBP4 5950 retinol binding protein 4, plasma cytosol Cellular component - TLR9 54106 toll-like receptor 9 cytoplasm Cellular component 19740627 TCN1 6947 transcobalamin I (vitamin B12 binding protein, R binder family) extracellular region Cellular component - DMXL2 23312 Dmx-like 2 cell junction Cellular component - CEP89 84902 centrosomal protein 89kDa nonmotile primary cilium assembly Biological process 23789104 PLIN2 123 perilipin 2 endoplasmic reticulum Cellular component 9003395 DCXR 51181 dicarbonyl/L-xylulose reductase oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor Molecular function 19442656 AEBP1 165 AE binding protein 1 zinc ion binding Molecular function - STK38L 23012 serine/threonine kinase 38 like magnesium ion binding Molecular function 15067004 PTGR1 22949 prostaglandin reductase 1 small molecule metabolic process Biological process - NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 positive regulation of gene expression Biological process - SNUPN 10073 snurportin 1 extracellular exosome Cellular component 23376485 SLC23A1 9963 solute carrier family 23 (ascorbic acid transporter), member 1 sodium-dependent L-ascorbate transmembrane transporter activity Molecular function 10631088 ADORA2A 135 adenosine A2a receptor postsynaptic density Cellular component - SCLT1 132320 sodium channel and clathrin linker 1 clustering of voltage-gated sodium channels Biological process - BDH1 622 3-hydroxybutyrate dehydrogenase, type 1 liver development Biological process - IL5RA 3568 interleukin 5 receptor, alpha integral component of membrane Cellular component - OR10G8 219869 olfactory receptor, family 10, subfamily G, member 8 detection of chemical stimulus involved in sensory perception of smell Biological process - FNTA 2339 farnesyltransferase, CAAX box, alpha microtubule associated complex Cellular component 19228685 IL6 3569 interleukin 6 response to calcium ion Biological process - ZNF589 51385 zinc finger protein 589 metal ion binding Molecular function - POLR2E 5434 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa nucleus Cellular component 9852112 PPP6C 5537 protein phosphatase 6, catalytic subunit protein serine/threonine phosphatase activity Molecular function 16716191 ZBTB8B 728116 zinc finger and BTB domain containing 8B DNA binding Molecular function - NEU1 4758 sialidase 1 (lysosomal sialidase) cellular protein metabolic process Biological process - SIX1 6495 SIX homeobox 1 kidney development Biological process - CTSH 1512 cathepsin H cysteine-type endopeptidase activity Molecular function 2849458 PKMYT1 9088 protein kinase, membrane associated tyrosine/threonine 1 protein phosphorylation Biological process - CARNS1 57571 carnosine synthase 1 metal ion binding Molecular function - MYBPC3 4607 myosin binding protein C, cardiac striated muscle myosin thick filament Cellular component - ZNF587 84914 zinc finger protein 587 DNA binding Molecular function - PLA2G5 5322 phospholipase A2, group V response to cAMP Biological process - POP1 10940 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) ribonuclease MRP complex Cellular component 8918471 WNT5A 7474 wingless-type MMTV integration site family, member 5A negative regulation of epithelial cell proliferation Biological process - RAP1BL 643752 RAP1B, member of RAS oncogene family pseudogene GTP binding Molecular function - PPP1R9B 84687 protein phosphatase 1, regulatory subunit 9B regulation of exit from mitosis Biological process 11278317 CLIC1 1192 chloride intracellular channel 1 blood microparticle Cellular component 22516433 CCL4 6351 chemokine (C-C motif) ligand 4 cell-cell signaling Biological process 2521882 HDAC10 83933 histone deacetylase 10 NAD-dependent histone deacetylase activity (H4-K16 specific) Molecular function - MAPK4 5596 mitogen-activated protein kinase 4 MAPK cascade Biological process 7969157 COG3 83548 component of oligomeric golgi complex 3 Golgi apparatus Cellular component - HSPA5 3309 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) midbody Cellular component 15166316 FZD3 7976 frizzled class receptor 3 hair follicle development Biological process - PIDD1 55367 p53-induced death domain protein 1 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Biological process 21726810 AGT 183 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) response to salt stress Biological process - FZD9 8326 frizzled class receptor 9 neuroblast proliferation Biological process - FKBP8 23770 FK506 binding protein 8, 38kDa negative regulation of apoptotic process Biological process - IL6R 3570 interleukin 6 receptor plasma membrane Cellular component - AQP1 358 aquaporin 1 (Colton blood group) metanephric descending thin limb development Biological process - FPGS 2356 folylpolyglutamate synthase liver development Biological process - SYVN1 84447 synovial apoptosis inhibitor 1, synoviolin endoplasmic reticulum Cellular component 23710284 ATP6V0C 527 ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c proton-transporting ATP synthase activity, rotational mechanism Molecular function 1709739 BCL11A 53335 B-cell CLL/lymphoma 11A (zinc finger protein) protein sumoylation Biological process - UGT2B17 7367 UDP glucuronosyltransferase 2 family, polypeptide B17 integral component of membrane Cellular component - OGG1 4968 8-oxoguanine DNA glycosylase damaged DNA binding Molecular function - ENO1 2023 enolase 1, (alpha) phosphopyruvate hydratase activity Molecular function - ARF4 378 ADP-ribosylation factor 4 protein transport Biological process - MAP4K1 11184 mitogen-activated protein kinase kinase kinase kinase 1 activation of JUN kinase activity Biological process 8824585 SCART1 619207 scavenger receptor protein family member receptor-mediated endocytosis Biological process - AANAT 15 aralkylamine N-acetyltransferase response to zinc ion Biological process - LTF 4057 lactotransferrin ossification Biological process - TBXA2R 6915 thromboxane A2 receptor blood coagulation Biological process - EDAR 10913 ectodysplasin A receptor salivary gland cavitation Biological process - NDST1 3340 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 deacetylase activity Molecular function - COL3A1 1281 collagen, type III, alpha 1 transforming growth factor beta receptor signaling pathway Biological process 16360482 PREP 5550 prolyl endopeptidase serine-type peptidase activity Molecular function 7959018 ARVCF 421 armadillo repeat gene deleted in velocardiofacial syndrome cell junction Cellular component - LSM11 134353 LSM11, U7 small nuclear RNA associated nucleus Cellular component - TIMM50 92609 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) nuclear speck Cellular component 16008839 CA9 768 carbonic anhydrase IX integral component of membrane Cellular component - ANXA9 8416 annexin A9 extracellular exosome Cellular component 23376485 RPS4X 6191 ribosomal protein S4, X-linked polysome Cellular component 8139551 OR2D3 120775 olfactory receptor, family 2, subfamily D, member 3 G-protein coupled receptor signaling pathway Biological process - PAPOLG 64895 poly(A) polymerase gamma mRNA polyadenylation Biological process - STAT5A 6776 signal transducer and activator of transcription 5A Peyer's patch development Biological process - ALDH6A1 4329 aldehyde dehydrogenase 6 family, member A1 mitochondrion Cellular component 1527093 ASNS 440 asparagine synthetase (glutamine-hydrolyzing) response to follicle-stimulating hormone Biological process - BRK1 55845 BRICK1, SCAR/WAVE actin-nucleating complex subunit positive regulation of cell proliferation Biological process - CALCOCO1 57658 calcium binding and coiled-coil domain 1 nucleus Cellular component - NUDT4 11163 nudix (nucleoside diphosphate linked moiety X)-type motif 4 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity Molecular function - ZNF662 389114 zinc finger protein 662 protein binding Molecular function 25416956 IFT20 90410 intraflagellar transport 20 ciliary tip Cellular component - S100B 6285 S100 calcium binding protein B regulation of neuronal synaptic plasticity Biological process - NDFIP1 80762 Nedd4 family interacting protein 1 negative regulation of gene expression Biological process 18776082 RELN 5649 reelin axon guidance Biological process - LMO4 8543 LIM domain only 4 transcription from RNA polymerase II promoter Biological process - PXK 54899 PX domain containing serine/threonine kinase ATP binding Molecular function 16142408 TIMM10 26519 translocase of inner mitochondrial membrane 10 homolog (yeast) mitochondrion Cellular component - ATP6V1C2 245973 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 protein dimerization activity Molecular function 21356312 HSD17B4 3295 hydroxysteroid (17-beta) dehydrogenase 4 3-hydroxyacyl-CoA dehydrogenase activity Molecular function - SLC22A5 6584 solute carrier family 22 (organic cation/carnitine transporter), member 5 PDZ domain binding Molecular function 15523054 PTH 5741 parathyroid hormone parathyroid hormone receptor binding Molecular function - MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase cellular response to alkaloid Biological process - ZG16 653808 zymogen granule protein 16 Golgi lumen Cellular component 17307141 HIST1H2AL 8332 histone cluster 1, H2al DNA binding Molecular function - IFI30 10437 interferon, gamma-inducible protein 30 cytoplasm Cellular component - PRAMEF2 65122 PRAME family member 2 negative regulation of retinoic acid receptor signaling pathway Biological process - ACADM 34 acyl-CoA dehydrogenase, C-4 to C-12 straight chain medium-chain fatty acid catabolic process Biological process 1970566 CXCL12 6387 chemokine (C-X-C motif) ligand 12 positive regulation of monocyte chemotaxis Biological process 18802065 ARSB 411 arylsulfatase B regulation of epithelial cell migration Biological process 19306108 CHST11 50515 carbohydrate (chondroitin 4) sulfotransferase 11 polysaccharide localization Biological process - PNPLA7 375775 patatin-like phospholipase domain containing 7 lysophospholipase activity Molecular function - ASCC3 10973 activating signal cointegrator 1 complex subunit 3 Golgi apparatus Cellular component - NCOA3 8202 nuclear receptor coactivator 3 nucleoplasm Cellular component - CCNH 902 cyclin H regulation of gene expression, epigenetic Biological process - CYP11A1 1583 cytochrome P450, family 11, subfamily A, polypeptide 1 hippocampus development Biological process - TPM3 7170 tropomyosin 3 extracellular exosome Cellular component 20458337 T 6862 T, brachyury homolog (mouse) negative regulation of transcription from RNA polymerase II promoter Biological process - LEF1 51176 lymphoid enhancer-binding factor 1 trachea gland development Biological process - MEF2C 4208 myocyte enhancer factor 2C B cell homeostasis Biological process - BZRAP1 9256 benzodiazepine receptor (peripheral) associated protein 1 mitochondrion Cellular component 9915832 SOX11 6664 SRY (sex determining region Y)-box 11 positive regulation of transcription from RNA polymerase II promoter Biological process 21124928 PTAFR 5724 platelet-activating factor receptor G-protein coupled purinergic nucleotide receptor signaling pathway Biological process - OR5P3 120066 olfactory receptor, family 5, subfamily P, member 3 G-protein coupled receptor signaling pathway Biological process - PPP2CA 5515 protein phosphatase 2, catalytic subunit, alpha isozyme mitochondrion Cellular component 11007961 LTA 4049 lymphotoxin alpha humoral immune response Biological process - PAFAH1B3 5050 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) membrane Cellular component 19946888 GRM3 2913 glutamate receptor, metabotropic 3 postsynaptic membrane Cellular component - BTNL9 153579 butyrophilin-like 9 integral component of membrane Cellular component - EID2 163126 EP300 interacting inhibitor of differentiation 2 transforming growth factor beta receptor complex assembly Biological process 14612439 HAUS2 55142 HAUS augmin-like complex, subunit 2 centrosome organization Biological process 19427217 CCL2 6347 chemokine (C-C motif) ligand 2 maternal process involved in female pregnancy Biological process - SS18L1 26039 synovial sarcoma translocation gene on chromosome 18-like 1 positive regulation of transcription, DNA-templated Biological process - OXLD1 339229 oxidoreductase-like domain containing 1 mitochondrion Cellular component - HNRNPH1 3187 heterogeneous nuclear ribonucleoprotein H1 (H) mRNA splicing, via spliceosome Biological process - KPNA3 3839 karyopherin alpha 3 (importin alpha 4) protein C-terminus binding Molecular function - SLC39A5 283375 solute carrier family 39 (zinc transporter), member 5 cellular response to zinc ion starvation Biological process - GPN2 54707 GPN-loop GTPase 2 hydrolase activity Molecular function - PCGF2 7703 polycomb group ring finger 2 protein ubiquitination Biological process - ERCC4 2072 excision repair cross-complementation group 4 resolution of meiotic recombination intermediates Biological process - FLVCR1 28982 feline leukemia virus subgroup C cellular receptor 1 cellular iron ion homeostasis Biological process - CACNA1A 773 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit cell projection Cellular component 16595610 APOB 338 apolipoprotein B neuronal cell body Cellular component 22897442 CCNG1 900 cyclin G1 mitotic G2 DNA damage checkpoint Biological process - NR2F2 7026 nuclear receptor subfamily 2, group F, member 2 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function 18798693 INPP5A 3632 inositol polyphosphate-5-phosphatase, 40kDa membrane Cellular component 8006039 NFASC 23114 neurofascin focal adhesion Cellular component 21423176 MDH2 4191 malate dehydrogenase 2, NAD (mitochondrial) mitochondrion Cellular component - PARK2 5071 parkin RBR E3 ubiquitin protein ligase negative regulation of reactive oxygen species metabolic process Biological process 18541373 PLCB3 5331 phospholipase C, beta 3 (phosphatidylinositol-specific) membrane Cellular component - BRD7 29117 bromodomain containing 7 transcription regulatory region DNA binding Molecular function 20228809 KIF4B 285643 kinesin family member 4B nucleoplasm Cellular component - FTH1 2495 ferritin, heavy polypeptide 1 protein binding Molecular function 15607035 SEC61G 23480 Sec61 gamma subunit cytosol Cellular component - SP4 6671 Sp4 transcription factor transcription from RNA polymerase II promoter Biological process - SERPINB5 5268 serpin peptidase inhibitor, clade B (ovalbumin), member 5 prostate gland morphogenesis Biological process - ZNF705G 100131980 zinc finger protein 705G DNA binding Molecular function - HESX1 8820 HESX homeobox 1 chromatin binding Molecular function - MR1 3140 major histocompatibility complex, class I-related antigen processing and presentation Biological process - CHUK 1147 conserved helix-loop-helix ubiquitous kinase nucleotide-binding oligomerization domain containing signaling pathway Biological process - ITGA2 3673 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) positive regulation of cell adhesion Biological process - FRMD5 84978 FERM domain containing 5 cytoplasm Cellular component - OCM 654231 oncomodulin calcium ion binding Molecular function 8354278 RPS6KA6 27330 ribosomal protein S6 kinase, 90kDa, polypeptide 6 negative regulation of ERK1 and ERK2 cascade Biological process - MYH10 4628 myosin, heavy chain 10, non-muscle spindle Cellular component - ATL3 25923 atlastin GTPase 3 Golgi organization Biological process 18270207 OR4C16 219428 olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene) transmembrane signaling receptor activity Molecular function - FZD7 8324 frizzled class receptor 7 regulation of transcription, DNA-templated Biological process 18681827 DDX60 55601 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 response to virus Biological process 21791617 TEAD3 7005 TEA domain family member 3 positive regulation of transcription from RNA polymerase II promoter Biological process - PKD1 5310 polycystic kidney disease 1 (autosomal dominant) cytoplasm Cellular component - LHX6 26468 LIM homeobox 6 sequence-specific DNA binding transcription factor activity Molecular function 10393337 PTH2 113091 parathyroid hormone 2 neuropeptide signaling pathway Biological process - RCVRN 5957 recoverin calcium ion binding Molecular function - SIRT1 23411 sirtuin 1 single strand break repair Biological process 20097625 APOA4 337 apolipoprotein A-IV cholesterol transporter activity Molecular function 1935934 INTU 27152 inturned planar cell polarity protein negative regulation of keratinocyte proliferation Biological process - PVRL1 5818 poliovirus receptor-related 1 (herpesvirus entry mediator C) growth cone membrane Cellular component - KIFAP3 22920 kinesin-associated protein 3 negative regulation of cell proliferation Biological process - DEFB124 245937 defensin, beta 124 cell surface Cellular component - NRG4 145957 neuregulin 4 epidermal growth factor receptor signaling pathway Biological process - LRRK1 79705 leucine-rich repeat kinase 1 identical protein binding Molecular function 19712061 OBSCN 84033 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF ankyrin binding Molecular function 18782775 NCK1 4690 NCK adaptor protein 1 positive regulation of T cell proliferation Biological process 12110186 PHKG1 5260 phosphorylase kinase, gamma 1 (muscle) carbohydrate metabolic process Biological process - TLL1 7092 tolloid-like 1 cell differentiation Biological process - TTN 7273 titin actinin binding Molecular function 11846417 PTCHD1 139411 patched domain containing 1 cognition Biological process 20844286 BLK 640 BLK proto-oncogene, Src family tyrosine kinase protein tyrosine kinase activity Molecular function 7845672 POLR2K 5440 polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa transcription initiation from RNA polymerase I promoter Biological process - THAP11 57215 THAP domain containing 11 transcription, DNA-templated Biological process - SLC25A27 9481 solute carrier family 25, member 27 generation of precursor metabolites and energy Biological process 10025957 PTPMT1 114971 protein tyrosine phosphatase, mitochondrial 1 glycerophospholipid biosynthetic process Biological process - DYRK1A 1859 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A protein serine/threonine/tyrosine kinase activity Molecular function - LRP1 4035 low density lipoprotein receptor-related protein 1 protein kinase C-activating G-protein coupled receptor signaling pathway Biological process - SERINC1 57515 serine incorporator 1 extracellular exosome Cellular component 23376485 CSF1 1435 colony stimulating factor 1 (macrophage) ossification Biological process - RFFL 117584 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase ligase activity Molecular function - OAS1 4938 2'-5'-oligoadenylate synthetase 1, 40/46kDa nucleus Cellular component - NGFR 4804 nerve growth factor receptor nerve development Biological process - ZNF333 84449 zinc finger protein 333 nucleus Cellular component - DAPK1 1612 death-associated protein kinase 1 intracellular signal transduction Biological process 10629061 CAD 790 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase lactation Biological process - CSDE1 7812 cold shock domain containing E1, RNA-binding DNA binding Molecular function - CYP2C9 1559 cytochrome P450, family 2, subfamily C, polypeptide 9 oxidation-reduction process Biological process 16401082 USF1 7391 upstream transcription factor 1 protein homodimerization activity Molecular function 2249772 KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog metal ion binding Molecular function - STK36 27148 serine/threonine kinase 36 positive regulation of smoothened signaling pathway Biological process - MB21D1 115004 Mab-21 domain containing 1 cyclic nucleotide biosynthetic process Biological process 23258413 VEZF1 7716 vascular endothelial zinc finger 1 cellular defense response Biological process 8035792 VPS35 55737 vacuolar protein sorting 35 homolog (S. cerevisiae) protein binding Molecular function 11102511 MORF4L2 9643 mortality factor 4 like 2 chromatin organization Biological process - BLVRA 644 biliverdin reductase A protein binding Molecular function 25416956 MEF2A 4205 myocyte enhancer factor 2A toll-like receptor 3 signaling pathway Biological process - RPRD1B 58490 regulation of nuclear pre-mRNA domain containing 1B positive regulation of cell proliferation Biological process 22264791 GRN 2896 granulin signal transduction Biological process 1542665 AGXT 189 alanine-glyoxylate aminotransferase peroxisomal matrix Cellular component - EPS8 2059 epidermal growth factor receptor pathway substrate 8 actin cytoskeleton reorganization Biological process - NPPB 4879 natriuretic peptide B regulation of blood vessel size Biological process - IRF2 3660 interferon regulatory factor 2 RNA polymerase II regulatory region sequence-specific DNA binding Molecular function 9540062 SFRP1 6422 secreted frizzled-related protein 1 regulation of angiogenesis Biological process - AFF4 27125 AF4/FMR2 family, member 4 regulation of transcription, DNA-templated Biological process - PGS1 9489 phosphatidylglycerophosphate synthase 1 phosphatidylglycerol biosynthetic process Biological process - SIRT2 22933 sirtuin 2 positive regulation of attachment of spindle microtubules to kinetochore Biological process - GTF2H4 2968 general transcription factor IIH, polypeptide 4, 52kDa core TFIIH complex Cellular component - TAZ 6901 tafazzin 1-acylglycerophosphocholine O-acyltransferase activity Molecular function 12930833 IKBKB 3551 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta cellular response to tumor necrosis factor Biological process 23091055 CCBL2 56267 cysteine conjugate-beta lyase 2 poly(A) RNA binding Molecular function 22681889 PARK7 11315 parkinson protein 7 negative regulation of protein export from nucleus Biological process 15983381 NUPL1 9818 nucleoporin like 1 mitotic cell cycle Biological process - ATP6V1H 51606 ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H interaction with host Biological process - ETNK1 55500 ethanolamine kinase 1 phosphatidylethanolamine biosynthetic process Biological process - OTOA 146183 otoancorin apical plasma membrane Cellular component - SULT1A1 6817 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 catecholamine metabolic process Biological process - SELT 51714 selenoprotein T selenocysteine incorporation Biological process 10567350 RPP25L 138716 ribonuclease P/MRP 25kDa subunit-like protein binding Molecular function 25416956 NR2E1 7101 nuclear receptor subfamily 2, group E, member 1 zinc ion binding Molecular function - TRIM4 89122 tripartite motif containing 4 ligase activity Molecular function - TRNT1 51095 tRNA nucleotidyl transferase, CCA-adding, 1 tRNA 3'-terminal CCA addition Biological process 25193871 NQO1 1728 NAD(P)H dehydrogenase, quinone 1 response to toxic substance Biological process 10393963 PLA2G4A 5321 phospholipase A2, group IVA (cytosolic, calcium-dependent) phospholipase A2 activity Molecular function - CASP3 836 caspase 3, apoptosis-related cysteine peptidase cysteine-type endopeptidase activity Molecular function - SLC22A4 6583 solute carrier family 22 (organic cation/zwitterion transporter), member 4 secondary active organic cation transmembrane transporter activity Molecular function 9426230 S1PR3 1903 sphingosine-1-phosphate receptor 3 negative regulation of establishment of endothelial barrier Biological process 24851274 DMXL2 23312 Dmx-like 2 synaptic vesicle Cellular component 11809763 PGM3 5238 phosphoglucomutase 3 magnesium ion binding Molecular function - VAMP4 8674 vesicle-associated membrane protein 4 exocytosis Biological process - RRAS2 22800 related RAS viral (r-ras) oncogene homolog 2 focal adhesion Cellular component 21423176 CNGB1 1258 cyclic nucleotide gated channel beta 1 visual perception Biological process 7682292 PCGF3 10336 polycomb group ring finger 3 nucleoplasm Cellular component - SLC4A7 9497 solute carrier family 4, sodium bicarbonate cotransporter, member 7 retinal cell programmed cell death Biological process - MYCBPAP 84073 MYCBP associated protein cell differentiation Biological process - U2AF2 11338 U2 small nuclear RNA auxiliary factor 2 gene expression Biological process - CDKN2D 1032 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) G1/S transition of mitotic cell cycle Biological process 10208428 CDK7 1022 cyclin-dependent kinase 7 transcription-coupled nucleotide-excision repair Biological process - TP53TG3B 729355 TP53 target 3B nucleus Cellular component - MAPK7 5598 mitogen-activated protein kinase 7 toll-like receptor 3 signaling pathway Biological process - ALOX15 246 arachidonate 15-lipoxygenase lipid particle Cellular component 19528634 SLC36A1 206358 solute carrier family 36 (proton/amino acid symporter), member 1 ion transport Biological process - TEFM 79736 transcription elongation factor, mitochondrial regulation of transcription, DNA-templated Biological process - PIK3R6 146850 phosphoinositide-3-kinase, regulatory subunit 6 phosphatidylinositol phosphorylation Biological process - ATL3 25923 atlastin GTPase 3 GTPase activity Molecular function 18270207 PHEX 5251 phosphate regulating endopeptidase homolog, X-linked organophosphate metabolic process Biological process - RPS17 6218 ribosomal protein S17 ribosomal small subunit biogenesis Biological process 18697920 JUN 3725 jun proto-oncogene liver development Biological process - FGD2 221472 FYVE, RhoGEF and PH domain containing 2 regulation of cell shape Biological process - TMED5 50999 transmembrane emp24 protein transport domain containing 5 cis-Golgi network Cellular component 19948005 RBM14 10432 RNA binding motif protein 14 histone deacetylation Biological process 11443112 VASP 7408 vasodilator-stimulated phosphoprotein protein binding Molecular function 16631741 RBM39 9584 RNA binding motif protein 39 RNA splicing Biological process - UNC5D 137970 unc-5 homolog D (C. elegans) cell surface Cellular component - TNNI3K 51086 TNNI3 interacting kinase protein serine/threonine kinase activity Molecular function - VIM 7431 vimentin cytoskeleton Cellular component 16130169 SLC23A1 9963 solute carrier family 23 (ascorbic acid transporter), member 1 vitamin metabolic process Biological process - TGFA 7039 transforming growth factor, alpha positive regulation of epidermal growth factor-activated receptor activity Biological process 11278323 BCL2L2 599 BCL2-like 2 extrinsic apoptotic signaling pathway in absence of ligand Biological process - RBM19 9904 RNA binding motif protein 19 multicellular organismal development Biological process - TNKS 8658 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase chromosome, telomeric region Cellular component 9822378 TNKS1BP1 85456 tankyrase 1 binding protein 1, 182kDa CCR4-NOT complex Cellular component 19558367 SHMT1 6470 serine hydroxymethyltransferase 1 (soluble) protein homotetramerization Biological process - CRYZ 1429 crystallin, zeta (quinone reductase) xenobiotic catabolic process Biological process 17497241 ADAMTSL3 57188 ADAMTS-like 3 proteinaceous extracellular matrix Cellular component - GPR139 124274 G protein-coupled receptor 139 protein dimerization activity Molecular function - CD28 940 CD28 molecule neurotrophin TRK receptor signaling pathway Biological process - PPAP2B 8613 phosphatidic acid phosphatase type 2B negative regulation of protein phosphorylation Biological process 20123964 MMP24 10893 matrix metallopeptidase 24 (membrane-inserted) neuronal stem cell maintenance Biological process - CRY1 1407 cryptochrome circadian clock 1 DNA damage induced protein phosphorylation Biological process - SEC61A2 55176 Sec61 alpha 2 subunit (S. cerevisiae) endoplasmic reticulum unfolded protein response Biological process - CLN8 2055 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) ceramide metabolic process Biological process 16086686 TRIOBP 11078 TRIO and F-actin binding protein midbody Cellular component - FGF23 8074 fibroblast growth factor 23 positive regulation of ERK1 and ERK2 cascade Biological process - MAPK11 5600 mitogen-activated protein kinase 11 gene expression Biological process - DEF8 54849 differentially expressed in FDCP 8 homolog (mouse) intracellular signal transduction Biological process - ALDH6A1 4329 aldehyde dehydrogenase 6 family, member A1 poly(A) RNA binding Molecular function 22658674 AGXT2 64902 alanine--glyoxylate aminotransferase 2 pyridoxal phosphate binding Molecular function - ADGRL1 22859 adhesion G protein-coupled receptor L1 latrotoxin receptor activity Molecular function - L2HGDH 79944 L-2-hydroxyglutarate dehydrogenase small molecule metabolic process Biological process - TFCP2 7024 transcription factor CP2 DNA binding Molecular function 8035790 CYP27A1 1593 cytochrome P450, family 27, subfamily A, polypeptide 1 cholesterol metabolic process Biological process - CHN1 1123 chimerin 1 positive regulation of GTPase activity Biological process - VANGL2 57216 VANGL planar cell polarity protein 2 stress fiber Cellular component - FOXO3 2309 forkhead box O3 positive regulation of erythrocyte differentiation Biological process 14734530 ARSB 411 arylsulfatase B rough endoplasmic reticulum Cellular component - KRT2 3849 keratin 2, type II cytoplasm Cellular component - ABR 29 active BCR-related regulation of small GTPase mediated signal transduction Biological process - FGF12 2257 fibroblast growth factor 12 protein binding Molecular function 25416956 CXCL11 6373 chemokine (C-X-C motif) ligand 11 inflammatory response Biological process - MAP2K1 5604 mitogen-activated protein kinase kinase 1 microtubule Cellular component - NDUFAF5 79133 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 extrinsic component of mitochondrial inner membrane Cellular component 18940309 IGFBP1 3484 insulin-like growth factor binding protein 1 signal transduction Biological process 2454104 PDHA2 5161 pyruvate dehydrogenase (lipoamide) alpha 2 glycolytic process Biological process - HCN1 348980 hyperpolarization activated cyclic nucleotide gated potassium channel 1 synaptic transmission Biological process - TNF 7124 tumor necrosis factor negative regulation of cell proliferation Biological process - SHH 6469 sonic hedgehog negative regulation of ureter smooth muscle cell differentiation Biological process - DCSTAMP 81501 dendrocyte expressed seven transmembrane protein integral component of plasma membrane Cellular component 20586129 POLG 5428 polymerase (DNA directed), gamma DNA binding Molecular function - KRT75 9119 keratin 75, type II keratin filament Cellular component - MRPL45 84311 mitochondrial ribosomal protein L45 protein binding Molecular function 25416956 ANKRD1 27063 ankyrin repeat domain 1 (cardiac muscle) cellular response to tumor necrosis factor Biological process 7730328 TRIM21 6737 tripartite motif containing 21 regulation of type I interferon production Biological process - VPS13D 55187 vacuolar protein sorting 13 homolog D (S. cerevisiae) intracellular Cellular component - CNGA2 1260 cyclic nucleotide gated channel alpha 2 Golgi membrane Cellular component - CALD1 800 caldesmon 1 tropomyosin binding Molecular function 1555769 TNFSF10 8743 tumor necrosis factor (ligand) superfamily, member 10 extrinsic apoptotic signaling pathway Biological process - RAB11FIP3 9727 RAB11 family interacting protein 3 (class II) protein homodimerization activity Molecular function 17030804 GRIK1 2897 glutamate receptor, ionotropic, kainate 1 adult behavior Biological process - CYP3A4 1576 cytochrome P450, family 3, subfamily A, polypeptide 4 testosterone 6-beta-hydroxylase activity Molecular function 3259858 CDS1 1040 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 small molecule metabolic process Biological process - COL8A2 1296 collagen, type VIII, alpha 2 protein binding, bridging Molecular function 2019595 IGSF1 3547 immunoglobulin superfamily, member 1 signal transduction Biological process 11266516 SLC25A19 60386 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 positive regulation of defense response to virus by host Biological process 22020285 CSNK2A1 1457 casein kinase 2, alpha 1 polypeptide NuRD complex Cellular component 17827154 PRDM14 63978 PR domain containing 14 transcription, DNA-templated Biological process - KLF4 9314 Kruppel-like factor 4 (gut) cellular response to hydrogen peroxide Biological process - ERN1 2081 endoplasmic reticulum to nucleus signaling 1 peptidyl-serine trans-autophosphorylation Biological process 21317875 OGT 8473 O-linked N-acetylglucosamine (GlcNAc) transferase signal transduction Biological process 9083067 UGT1A1 54658 UDP glucuronosyltransferase 1 family, polypeptide A1 acute-phase response Biological process - HTR2A 3356 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled positive regulation of ERK1 and ERK2 cascade Biological process 19057895 VCL 7414 vinculin blood coagulation Biological process - BNIP1 662 BCL2/adenovirus E1B 19kDa interacting protein 1 endoplasmic reticulum membrane fusion Biological process 15272311 MYF6 4618 myogenic factor 6 (herculin) nucleoplasm Cellular component - RPTOR 57521 regulatory associated protein of MTOR, complex 1 transcription initiation from RNA polymerase II promoter Biological process - GNG12 55970 guanine nucleotide binding protein (G protein), gamma 12 signal transducer activity Molecular function - CPLX1 10815 complexin 1 neuronal cell body Cellular component - ZNF460 10794 zinc finger protein 460 metal ion binding Molecular function - SNW1 22938 SNW domain containing 1 viral process Biological process - RANBP2 5903 RAN binding protein 2 membrane Cellular component 19946888 MECP2 4204 methyl CpG binding protein 2 glucocorticoid metabolic process Biological process - ARHGEF7 8874 Rho guanine nucleotide exchange factor (GEF) 7 hematopoietic progenitor cell differentiation Biological process - SPPL3 121665 signal peptide peptidase like 3 aspartic endopeptidase activity, intramembrane cleaving Molecular function 16873890 CCND3 896 cyclin D3 T cell proliferation Biological process - RNPS1 10921 RNA binding protein S1, serine-rich domain nucleotide binding Molecular function - PTEN 5728 phosphatase and tensin homolog phosphatidylinositol-3-phosphatase activity Molecular function 9811831 BCL10 8915 B-cell CLL/lymphoma 10 positive regulation of mast cell cytokine production Biological process 16647297 EDN3 1908 endothelin 3 regulation of vasoconstriction Biological process - SULT2A1 6822 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 small molecule metabolic process Biological process - GALNT4 8693 polypeptide N-acetylgalactosaminyltransferase 4 polypeptide N-acetylgalactosaminyltransferase activity Molecular function - SIK2 23235 salt-inducible kinase 2 cytoplasm Cellular component - HLA-DRB5 3127 major histocompatibility complex, class II, DR beta 5 extracellular space Cellular component 16502470 RAB42 115273 RAB42, member RAS oncogene family Golgi apparatus Cellular component - MAP3K10 4294 mitogen-activated protein kinase kinase kinase 10 activation of JNKK activity Biological process - COPS5 10987 COP9 signalosome subunit 5 ubiquitin-specific protease activity Molecular function 19246649 BIRC2 329 baculoviral IAP repeat containing 2 XY body Cellular component - ABCF3 55324 ATP-binding cassette, sub-family F (GCN20), member 3 protein binding Molecular function 21516116 CD93 22918 CD93 molecule macrophage activation Biological process 9047234 NDUFA13 51079 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 nucleoplasm Cellular component 10924506 ATP6V1G3 127124 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 vacuolar proton-transporting V-type ATPase complex Cellular component - RORB 6096 RAR-related orphan receptor B transcription factor binding Molecular function - SNX3 8724 sorting nexin 3 extrinsic component of membrane Cellular component - RASL12 51285 RAS-like, family 12 GTP binding Molecular function - PILRA 29992 paired immunoglobin-like type 2 receptor alpha protein binding Molecular function 10660620 STMN1 3925 stathmin 1 extracellular exosome Cellular component 20458337 SMG7 9887 SMG7 nonsense mediated mRNA decay factor nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Biological process 16488880 POLR1D 51082 polymerase (RNA) I polypeptide D, 16kDa protein binding Molecular function 16189514 SH3BP2 6452 SH3-domain binding protein 2 positive regulation of signal transduction Biological process 9299232 COMMD8 54951 COMM domain containing 8 transcription, DNA-templated Biological process - CDK13 8621 cyclin-dependent kinase 13 cytoplasm Cellular component - ETS1 2113 v-ets avian erythroblastosis virus E26 oncogene homolog 1 positive regulation of erythrocyte differentiation Biological process 8620536 LYPLA2 11313 lysophospholipase II hydrolase activity Molecular function - RPGRIP1L 23322 RPGRIP1-like in utero embryonic development Biological process - NUP210L 91181 nucleoporin 210kDa-like integral component of membrane Cellular component - PRDM5 11107 PR domain containing 5 sequence-specific DNA binding Molecular function 17636019 KRTAP10-2 386679 keratin associated protein 10-2 keratin filament Cellular component - TPR 7175 translocated promoter region, nuclear basket protein negative regulation of RNA export from nucleus Biological process 21613532 CTAGE5 4253 CTAGE family, member 5 protein binding Molecular function 25416956 APEX1 328 APEX nuclease (multifunctional DNA repair enzyme) 1 transcription factor complex Cellular component - SMAD4 4089 SMAD family member 4 DNA binding Molecular function 9389648 ERI2 112479 ERI1 exoribonuclease family member 2 DNA catabolic process, exonucleolytic Biological process - BMP10 27302 bone morphogenetic protein 10 SMAD protein signal transduction Biological process - PTCHD4 442213 patched domain containing 4 hedgehog receptor activity Molecular function - ARHGEF11 9826 Rho guanine nucleotide exchange factor (GEF) 11 cytokinesis Biological process 10026210 UPP1 7378 uridine phosphorylase 1 nucleobase-containing small molecule metabolic process Biological process - TCAP 8557 titin-cap sarcomere organization Biological process 17921333 HYAL1 3373 hyaluronoglucosaminidase 1 cellular response to pH Biological process 19478093 QPCT 25797 glutaminyl-peptide cyclotransferase cellular protein modification process Biological process 7999256 LIG4 3981 ligase IV, DNA, ATP-dependent DNA binding Molecular function 8798671 KLRK1 22914 killer cell lectin-like receptor subfamily K, member 1 plasma membrane Cellular component - ANGPT2 285 angiopoietin 2 glomerulus vasculature development Biological process - UAP1 6675 UDP-N-acetylglucosamine pyrophosphorylase 1 protein N-linked glycosylation via asparagine Biological process - NUDT2 318 nudix (nucleoside diphosphate linked moiety X)-type motif 2 nucleobase-containing compound metabolic process Biological process 7487923 GSTM4 2948 glutathione S-transferase mu 4 protein binding Molecular function 25416956 KCNA1 3736 potassium channel, voltage gated shaker related subfamily A, member 1 juxtaparanode region of axon Cellular component - IFNA2 3440 interferon, alpha 2 defense response to virus Biological process 22783022 SCP2 6342 sterol carrier protein 2 receptor binding Molecular function 20178365 CAMK2B 816 calcium/calmodulin-dependent protein kinase II beta positive regulation of synapse maturation Biological process - T 6862 T, brachyury homolog (mouse) somitogenesis Biological process - TNF 7124 tumor necrosis factor positive regulation of interleukin-8 biosynthetic process Biological process 20551324 CYP2A6 1548 cytochrome P450, family 2, subfamily A, polypeptide 6 coumarin 7-hydroxylase activity Molecular function 16086027 TNNI2 7136 troponin I type 2 (skeletal, fast) muscle filament sliding Biological process - CFAP46 54777 cilia and flagella associated protein 46 axoneme Cellular component - GPER1 2852 G protein-coupled estrogen receptor 1 positive regulation of ERK1 and ERK2 cascade Biological process - MRGPRE 116534 MAS-related GPR, member E G-protein coupled receptor signaling pathway Biological process - CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 cellular lipid metabolic process Biological process - SQSTM1 8878 sequestosome 1 PML body Cellular component 20168092 NLRC3 197358 NLR family, CARD domain containing 3 molecular_function Molecular function - SOX11 6664 SRY (sex determining region Y)-box 11 positive regulation of transcription, DNA-templated Biological process - HAL 3034 histidine ammonia-lyase small molecule metabolic process Biological process - OR14I1 401994 olfactory receptor, family 14, subfamily I, member 1 detection of chemical stimulus involved in sensory perception of smell Biological process - DUSP4 1846 dual specificity phosphatase 4 protein tyrosine/serine/threonine phosphatase activity Molecular function - LDLRAD4 753 low density lipoprotein receptor class A domain containing 4 early endosome membrane Cellular component - PRKCE 5581 protein kinase C, epsilon cytosol Cellular component - HSPG2 3339 heparan sulfate proteoglycan 2 carbohydrate metabolic process Biological process - RPS8 6202 ribosomal protein S8 cytoplasm Cellular component - FMNL1 752 formin-like 1 extracellular exosome Cellular component 20458337 SOX4 6659 SRY (sex determining region Y)-box 4 T cell differentiation Biological process - NLRP3 114548 NLR family, pyrin domain containing 3 cellular response to lipopolysaccharide Biological process 12483741 GIPC1 10755 GIPC PDZ domain containing family, member 1 protein homodimerization activity Molecular function - EID3 493861 EP300 interacting inhibitor of differentiation 3 Smc5-Smc6 complex Cellular component 18086888 GSTT2B 653689 glutathione S-transferase theta 2B (gene/pseudogene) extracellular exosome Cellular component 23533145 GNB1 2782 guanine nucleotide binding protein (G protein), beta polypeptide 1 cell body Cellular component - POM121C 100101267 POM121 transmembrane nucleoporin C protein transport Biological process - CYB561D1 284613 cytochrome b561 family, member D1 integral component of membrane Cellular component - AXIN2 8313 axin 2 negative regulation of cell proliferation Biological process 16247484 ATP2C1 27032 ATPase, Ca++ transporting, type 2C, member 1 ATP binding Molecular function - RPL4 6124 ribosomal protein L4 SRP-dependent cotranslational protein targeting to membrane Biological process - CYP2J2 1573 cytochrome P450, family 2, subfamily J, polypeptide 2 icosanoid metabolic process Biological process 8631948 CDC25A 993 cell division cycle 25A protein binding Molecular function 11298456 SMURF1 57154 SMAD specific E3 ubiquitin protein ligase 1 protein targeting to vacuole involved in autophagy Biological process 22020285 GABRB2 2561 gamma-aminobutyric acid (GABA) A receptor, beta 2 synaptic transmission Biological process - SGK3 23678 serum/glucocorticoid regulated kinase family, member 3 response to stress Biological process 10548550 ACOX1 51 acyl-CoA oxidase 1, palmitoyl nucleus Cellular component - ADD2 119 adducin 2 (beta) actin binding Molecular function 1840603 MED14 9282 mediator complex subunit 14 ligand-dependent nuclear receptor transcription coactivator activity Molecular function 10235266 CREB5 9586 cAMP responsive element binding protein 5 sequence-specific DNA binding Molecular function - CEP350 9857 centrosomal protein 350kDa nucleoplasm Cellular component - CCR6 1235 chemokine (C-C motif) receptor 6 receptor activity Molecular function 9186513 MLF1 4291 myeloid leukemia factor 1 protein binding Molecular function 12176995 ISL1 3670 ISL LIM homeobox 1 neuron fate specification Biological process - KRT1 3848 keratin 1, type II plasma membrane Cellular component - CYP26B1 56603 cytochrome P450, family 26, subfamily B, polypeptide 1 xenobiotic metabolic process Biological process - KNDC1 85442 kinase non-catalytic C-lobe domain (KIND) containing 1 positive regulation of GTPase activity Biological process - ALDH3A2 224 aldehyde dehydrogenase 3 family, member A2 endoplasmic reticulum membrane Cellular component - IL2RG 3561 interleukin 2 receptor, gamma integral component of plasma membrane Cellular component 8514792 TCFL5 10732 transcription factor-like 5 (basic helix-loop-helix) cell differentiation Biological process - PEX1 5189 peroxisomal biogenesis factor 1 protein binding Molecular function 16257970 CLK4 57396 CDC-like kinase 4 nucleus Cellular component - SKP2 6502 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase regulation of apoptotic process Biological process 23277542 NEUROG1 4762 neurogenin 1 inner ear morphogenesis Biological process - ZNF513 130557 zinc finger protein 513 regulation of transcription, DNA-templated Biological process - CSTA 1475 cystatin A (stefin A) negative regulation of endopeptidase activity Biological process - CXCL1 2919 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) inflammatory response Biological process - SIRPG 55423 signal-regulatory protein gamma plasma membrane Cellular component - MCM7 4176 minichromosome maintenance complex component 7 DNA strand elongation involved in DNA replication Biological process - HAGH 3029 hydroxyacylglutathione hydrolase glutathione biosynthetic process Biological process 8550579 CYP7B1 9420 cytochrome P450, family 7, subfamily B, polypeptide 1 bile acid biosynthetic process Biological process - TNFSF14 8740 tumor necrosis factor (ligand) superfamily, member 14 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 12393901 PRDX1 5052 peroxiredoxin 1 removal of superoxide radicals Biological process - NPC2 10577 Niemann-Pick disease, type C2 cholesterol efflux Biological process 16141411 D2HGDH 728294 D-2-hydroxyglutarate dehydrogenase oxidation-reduction process Biological process - TBC1D20 128637 TBC1 domain family, member 20 virion assembly Biological process 21680502 TMUB2 79089 transmembrane and ubiquitin-like domain containing 2 integral component of membrane Cellular component - DIEXF 27042 digestive organ expansion factor homolog (zebrafish) U3 snoRNA binding Molecular function - UBA52 7311 ubiquitin A-52 residue ribosomal protein fusion product 1 Fc-epsilon receptor signaling pathway Biological process - PLAU 5328 plasminogen activator, urokinase regulation of smooth muscle cell migration Biological process 8837777 SMG7 9887 SMG7 nonsense mediated mRNA decay factor cytoplasm Cellular component - CRELD2 79174 cysteine-rich with EGF-like domains 2 endoplasmic reticulum Cellular component - EPHB3 2049 EPH receptor B3 corpus callosum development Biological process - NTS 4922 neurotensin transport vesicle Cellular component - METTL23 124512 methyltransferase like 23 integral component of membrane Cellular component - NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 response to oxidative stress Biological process - TMTC2 160335 transmembrane and tetratricopeptide repeat containing 2 endoplasmic reticulum membrane Cellular component 24764305 RIPK4 54101 receptor-interacting serine-threonine kinase 4 membrane Cellular component - OR56A4 120793 olfactory receptor, family 56, subfamily A, member 4 olfactory receptor activity Molecular function - UROS 7390 uroporphyrinogen III synthase porphyrin-containing compound metabolic process Biological process - SCNM1 79005 sodium channel modifier 1 enzyme binding Molecular function 23382074 BCAT1 586 branched chain amino-acid transaminase 1, cytosolic L-isoleucine transaminase activity Molecular function - VRTN 55237 vertebrae development associated transposase activity Molecular function - RASGEF1A 221002 RasGEF domain family, member 1A small GTPase mediated signal transduction Biological process - IGF1 3479 insulin-like growth factor 1 (somatomedin C) negative regulation of release of cytochrome c from mitochondria Biological process - KCNJ11 3767 potassium channel, inwardly rectifying subfamily J, member 11 intercalated disc Cellular component - FGB 2244 fibrinogen beta chain blood microparticle Cellular component 22516433 WDFY1 57590 WD repeat and FYVE domain containing 1 nucleus Cellular component 11739631 CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa innate immune response Biological process - CYP3A5 1577 cytochrome P450, family 3, subfamily A, polypeptide 5 drug catabolic process Biological process 15039299 PMPCA 23203 peptidase (mitochondrial processing) alpha protein targeting to mitochondrion Biological process - KCNS3 3790 potassium voltage-gated channel, modifier subfamily S, member 3 synaptic transmission Biological process - SP2 6668 Sp2 transcription factor regulation of transcription from RNA polymerase II promoter Biological process 1341900 ZNF451 26036 zinc finger protein 451 regulation of transcription, DNA-templated Biological process - SPARC 6678 secreted protein, acidic, cysteine-rich (osteonectin) ossification Biological process - COCH 1690 cochlin protein binding Molecular function 21886777 PSMG1 8624 proteasome (prosome, macropain) assembly chaperone 1 cerebellar granule cell precursor proliferation Biological process - CIPC 85457 CLOCK-interacting pacemaker transcription, DNA-templated Biological process - METTL17 64745 methyltransferase like 17 nucleoplasm Cellular component - UBB 7314 ubiquitin B stress-activated MAPK cascade Biological process - UBE2E3 10477 ubiquitin-conjugating enzyme E2E 3 ubiquitin-protein transferase activity Molecular function 20061386 OTOP3 347741 otopetrin 3 integral component of membrane Cellular component - NR5A1 2516 nuclear receptor subfamily 5, group A, member 1 sequence-specific DNA binding Molecular function - BMP2 650 bone morphogenetic protein 2 activation of MAPK activity Biological process 17202865 CLECL1 160365 C-type lectin-like 1 integral component of membrane Cellular component - SLC9A3R2 9351 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 protein binding Molecular function 11285285 ICK 22858 intestinal cell (MAK-like) kinase nucleus Cellular component - DDX3Y 8653 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked RNA secondary structure unwinding Biological process - CDC42 998 cell division cycle 42 cytosol Cellular component - MARK1 4139 MAP/microtubule affinity-regulating kinase 1 cytoplasm Cellular component - PRKAA1 5562 protein kinase, AMP-activated, alpha 1 catalytic subunit rhythmic process Biological process - EYA3 2140 EYA transcriptional coactivator and phosphatase 3 anatomical structure morphogenesis Biological process 9020840 TGM2 7052 transglutaminase 2 protein binding Molecular function 16301118 RHOT1 55288 ras homolog family member T1 integral component of mitochondrial outer membrane Cellular component 12482879 MYC 4609 v-myc avian myelocytomatosis viral oncogene homolog positive regulation of mesenchymal cell proliferation Biological process - STUB1 10273 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase misfolded protein binding Molecular function 16831871 PSMD4 5710 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 programmed cell death Biological process - PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 positive regulation of peptidyl-serine phosphorylation Biological process 19667065 UBA7 7318 ubiquitin-like modifier activating enzyme 7 protein binding Molecular function 16189514 ARF3 377 ADP-ribosylation factor 3 phosphatidylinositol biosynthetic process Biological process - CXCR1 3577 chemokine (C-X-C motif) receptor 1 interleukin-8 binding Molecular function 11564821 NDUFS1 4719 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) cellular respiration Biological process 15186778 CLEC2B 9976 C-type lectin domain family 2, member B carbohydrate binding Molecular function - SBDS 51119 Shwachman-Bodian-Diamond syndrome leukocyte chemotaxis Biological process 14743349 TRPV4 59341 transient receptor potential cation channel, subfamily V, member 4 positive regulation of cytosolic calcium ion concentration Biological process 18458941 ATIC 471 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase extracellular exosome Cellular component 19056867 PARK2 5071 parkin RBR E3 ubiquitin protein ligase ubiquitin conjugating enzyme binding Molecular function 11439185 HIST1H3I 8354 histone cluster 1, H3i nucleosome assembly Biological process 25615412 SIX5 147912 SIX homeobox 5 cytoplasm Cellular component - BLOC1S6 26258 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin membrane fusion Biological process - AGAP1 116987 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 phospholipid binding Molecular function 18954304 EIF2AK2 5610 eukaryotic translation initiation factor 2-alpha kinase 2 protein autophosphorylation Biological process 16216244 NTRK1 4914 neurotrophic tyrosine kinase, receptor, type 1 positive regulation of Ras protein signal transduction Biological process 15488758 SRF 6722 serum response factor (c-fos serum response element-binding transcription factor) muscle cell cellular homeostasis Biological process - SLC2A4 6517 solute carrier family 2 (facilitated glucose transporter), member 4 hexose transmembrane transport Biological process - KLHL10 317719 kelch-like family member 10 Cul3-RING ubiquitin ligase complex Cellular component - JAK2 3717 Janus kinase 2 heme binding Molecular function 21036157 FOXO4 4303 forkhead box O4 cytosol Cellular component 22972301 CASP3 836 caspase 3, apoptosis-related cysteine peptidase heart development Biological process - ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like regulation of type B pancreatic cell development Biological process - PLCB3 5331 phospholipase C, beta 3 (phosphatidylinositol-specific) calmodulin binding Molecular function 12821674 CD44 960 CD44 molecule (Indian blood group) cell surface Cellular component 16809613 TNNC1 7134 troponin C type 1 (slow) actin cytoskeleton Cellular component - CYTH1 9267 cytohesin 1 regulation of cell adhesion Biological process 12606567 POU6F2 11281 POU class 6 homeobox 2 transcription from RNA polymerase II promoter Biological process 8601806 PLA2G4A 5321 phospholipase A2, group IVA (cytosolic, calcium-dependent) arachidonic acid metabolic process Biological process - TRAF2 7186 TNF receptor-associated factor 2 cell cortex Cellular component - ZBTB49 166793 zinc finger and BTB domain containing 49 cytoplasm Cellular component 25245946 INPP5K 51763 inositol polyphosphate-5-phosphatase K negative regulation of transcription, DNA-templated Biological process - KRTAP10-12 386685 keratin associated protein 10-12 keratin filament Cellular component - SLC36A2 153201 solute carrier family 36 (proton/amino acid symporter), member 2 hydrogen:amino acid symporter activity Molecular function - OIT3 170392 oncoprotein induced transcript 3 calcium ion binding Molecular function - UBA52 7311 ubiquitin A-52 residue ribosomal protein fusion product 1 transmembrane transport Biological process - IQGAP3 128239 IQ motif containing GTPase activating protein 3 small GTPase mediated signal transduction Biological process - TUBA3E 112714 tubulin, alpha 3e biological_process Biological process - DMBX1 127343 diencephalon/mesencephalon homeobox 1 negative regulation of transcription, DNA-templated Biological process - SLC26A4 5172 solute carrier family 26 (anion exchanger), member 4 integral component of membrane Cellular component - NKRF 55922 NFKB repressing factor endoplasmic reticulum Cellular component - S100B 6285 S100 calcium binding protein B regulation of cell shape Biological process - CRH 1392 corticotropin releasing hormone positive regulation of cell proliferation Biological process - BMPR1A 657 bone morphogenetic protein receptor, type IA pituitary gland development Biological process - SLC24A2 25769 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 calcium channel activity Molecular function - BIRC6 57448 baculoviral IAP repeat containing 6 positive regulation of cell proliferation Biological process - MAPK10 5602 mitogen-activated protein kinase 10 innate immune response Biological process - ZNF318 24149 zinc finger protein 318 nucleoplasm Cellular component - DMRT1 1761 doublesex and mab-3 related transcription factor 1 sequence-specific DNA binding transcription factor activity Molecular function - MRPL54 116541 mitochondrial ribosomal protein L54 mitochondrial inner membrane Cellular component - SLC51B 123264 solute carrier family 51, beta subunit protein complex Cellular component - BRF1 2972 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit gene expression Biological process - ORC2 4999 origin recognition complex, subunit 2 membrane Cellular component 19946888 HRH2 3274 histamine receptor H2 synaptic transmission, dopaminergic Biological process - ACER2 340485 alkaline ceramidase 2 dihydroceramidase activity Molecular function 20628055 VPS54 51542 vacuolar protein sorting 54 homolog (S. cerevisiae) protein binding Molecular function 15878329 OR2G6 391211 olfactory receptor, family 2, subfamily G, member 6 detection of chemical stimulus involved in sensory perception of smell Biological process - MAPT 4137 microtubule-associated protein tau nuclear periphery Cellular component 19157893 USP7 7874 ubiquitin specific peptidase 7 (herpes virus-associated) transcription factor binding Molecular function 16964248 SYNE1 23345 spectrin repeat containing, nuclear envelope 1 cytoskeleton Cellular component - PDE6A 5145 phosphodiesterase 6A, cGMP-specific, rod, alpha visual perception Biological process - CALCA 796 calcitonin-related polypeptide alpha hormone activity Molecular function - CD36 948 CD36 molecule (thrombospondin receptor) transforming growth factor beta binding Molecular function - FAR2P1 440905 fatty acyl CoA reductase 2 pseudogene 1 fatty-acyl-CoA reductase (alcohol-forming) activity Molecular function - PARK7 11315 parkinson protein 7 membrane depolarization Biological process - COL7A1 1294 collagen, type VII, alpha 1 endodermal cell differentiation Biological process 23154389 BCL2 596 B-cell CLL/lymphoma 2 humoral immune response Biological process 1908951 SPSB1 80176 splA/ryanodine receptor domain and SOCS box containing 1 protein ubiquitination Biological process - Sep-07 989 septin 7 identical protein binding Molecular function 22064074 SMPD2 6610 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) caveola Cellular component - CHEK1 1111 checkpoint kinase 1 condensed nuclear chromosome Cellular component 9382850 MRPL12 6182 mitochondrial ribosomal protein L12 mitochondrial inner membrane Cellular component - DUSP15 128853 dual specificity phosphatase 15 plasma membrane Cellular component - AMMECR1 9949 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 molecular_function Molecular function - SNX33 257364 sorting nexin 33 identical protein binding Molecular function 19487689 HMGA1 3159 high mobility group AT-hook 1 retinoid X receptor binding Molecular function 10428834 PSMB10 5699 proteasome (prosome, macropain) subunit, beta type, 10 regulation of apoptotic process Biological process - PRTN3 5657 proteinase 3 extracellular space Cellular component 16502470 DAP3 7818 death associated protein 3 mitochondrial translational elongation Biological process - RDH8 50700 retinol dehydrogenase 8 (all-trans) retinoid metabolic process Biological process - DNAJC19 131118 DnaJ (Hsp40) homolog, subfamily C, member 19 protein targeting to mitochondrion Biological process - IFNA2 3440 interferon, alpha 2 negative regulation of gene expression Biological process 20554961 CXCL13 10563 chemokine (C-X-C motif) ligand 13 lymph node development Biological process - ZNF251 90987 zinc finger protein 251 regulation of transcription, DNA-templated Biological process - SAE1 10055 SUMO1 activating enzyme subunit 1 ubiquitin activating enzyme activity Molecular function 10187858 GRK5 2869 G protein-coupled receptor kinase 5 beta-adrenergic receptor kinase activity Molecular function 20038610 NOL3 8996 nucleolar protein 3 (apoptosis repressor with CARD domain) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway Biological process 15004034 DDX54 79039 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 regulation of transcription, DNA-templated Biological process - OR2T33 391195 olfactory receptor, family 2, subfamily T, member 33 sensory perception of smell Biological process - UBB 7314 ubiquitin B extracellular exosome Cellular component 23533145 NTSR2 23620 neurotensin receptor 2 integral component of plasma membrane Cellular component 9851594 PIFO 128344 primary cilia formation kinesin binding Molecular function 20643351 ARL13B 200894 ADP-ribosylation factor-like 13B cilium Cellular component - CDK19 23097 cyclin-dependent kinase 19 protein phosphorylation Biological process - ITGA3 3675 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) dendritic spine maintenance Biological process - ACTC1 70 actin, alpha, cardiac muscle 1 apoptotic process Biological process - UTS2R 2837 urotensin 2 receptor recycling endosome Cellular component - ORC1 4998 origin recognition complex, subunit 1 G1/S transition of mitotic cell cycle Biological process - KRTAP2-1 81872 keratin associated protein 2-1 keratin filament Cellular component - CNDP2 55748 CNDP dipeptidase 2 (metallopeptidase M20 family) cellular nitrogen compound metabolic process Biological process - MUC3A 4584 mucin 3A, cell surface associated O-glycan processing Biological process - UBXN6 80700 UBX domain protein 6 microtubule organizing center Cellular component - ATP2B4 493 ATPase, Ca++ transporting, plasma membrane 4 negative regulation of peptidyl-cysteine S-nitrosylation Biological process 18591664 ATP2A2 488 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 S100 protein binding Molecular function 12804600 FOXP3 50943 forkhead box P3 negative regulation of CREB transcription factor activity Biological process 16652169 AP1M2 10053 adaptor-related protein complex 1, mu 2 subunit cytoplasmic vesicle membrane Cellular component - TOP1 7150 topoisomerase (DNA) I core promoter sequence-specific DNA binding Molecular function 22904072 PTK2B 2185 protein tyrosine kinase 2 beta positive regulation of synaptic transmission, glutamatergic Biological process - RIMS2 9699 regulating synaptic membrane exocytosis 2 metal ion binding Molecular function - TGS1 96764 trimethylguanosine synthase 1 small nuclear ribonucleoprotein complex Cellular component 16687569 RPS6 6194 ribosomal protein S6 rRNA processing Biological process 18697920 HTR3B 9177 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic synaptic transmission Biological process 9950429 NFKBIA 4792 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha Fc-epsilon receptor signaling pathway Biological process - GIPR 2696 gastric inhibitory polypeptide receptor peptide hormone binding Molecular function - CIB2 10518 calcium and integrin binding family member 2 blood microparticle Cellular component 22516433 FOXO4 4303 forkhead box O4 innate immune response Biological process - CLPX 10845 caseinolytic mitochondrial matrix peptidase chaperone subunit mitochondrial nucleoid Cellular component 18063578 FREM1 158326 FRAS1 related extracellular matrix 1 craniofacial suture morphogenesis Biological process 21931569 ATP6V1B1 525 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 ossification Biological process 16433694 BMX 660 BMX non-receptor tyrosine kinase peptidyl-tyrosine autophosphorylation Biological process - CTSG 1511 cathepsin G neutrophil mediated killing of gram-positive bacterium Biological process - VCL 7414 vinculin negative regulation of cell migration Biological process 15494027 USP50 373509 ubiquitin specific peptidase 50 ubiquitin-specific protease activity Molecular function - LARS 51520 leucyl-tRNA synthetase regulation of translational fidelity Biological process - MTNR1B 4544 melatonin receptor 1B integral component of plasma membrane Cellular component 7568007 ACP5 54 acid phosphatase 5, tartrate resistant bone morphogenesis Biological process - SEL1L 6400 sel-1 suppressor of lin-12-like (C. elegans) Hrd1p ubiquitin ligase complex Cellular component 23710284 CRHR1 1394 corticotropin releasing hormone receptor 1 cellular response to corticotropin-releasing hormone stimulus Biological process 18292205 PTCD1 26024 pentatricopeptide repeat domain 1 mitochondrion Cellular component 19651879 CISH 1154 cytokine inducible SH2-containing protein cytokine-mediated signaling pathway Biological process - PIK3C2B 5287 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta inflammatory response Biological process - GLT1D1 144423 glycosyltransferase 1 domain containing 1 cytoplasm Cellular component - GDF11 10220 growth differentiation factor 11 transforming growth factor beta receptor binding Molecular function - FYN 2534 FYN proto-oncogene, Src family tyrosine kinase growth factor receptor binding Molecular function 16479011 CNTNAP2 26047 contactin associated protein-like 2 cell adhesion Biological process - C7orf73 647087 chromosome 7 open reading frame 73 mitochondrial membrane Cellular component - MEOX1 4222 mesenchyme homeobox 1 sequence-specific DNA binding transcription factor activity Molecular function - ZRANB3 84083 zinc finger, RAN-binding domain containing 3 negative regulation of DNA recombination Biological process 22704558 NME1 4830 NME/NM23 nucleoside diphosphate kinase 1 nucleoside diphosphate kinase activity Molecular function 12972261 ANAPC11 51529 anaphase promoting complex subunit 11 mitotic spindle assembly checkpoint Biological process - GLA 2717 galactosidase, alpha negative regulation of nitric-oxide synthase activity Biological process - ADCY7 113 adenylate cyclase 7 transmembrane transport Biological process - RNF168 165918 ring finger protein 168, E3 ubiquitin protein ligase cellular protein metabolic process Biological process - ANG 283 angiogenin, ribonuclease, RNase A family, 5 growth cone Cellular component - MEGF10 84466 multiple EGF-like-domains 10 phagocytic cup Cellular component - SLC38A2 54407 solute carrier family 38, member 2 amino acid transmembrane transporter activity Molecular function - MSMO1 6307 methylsterol monooxygenase 1 small molecule metabolic process Biological process - KIF23 9493 kinesin family member 23 mitotic cytokinesis Biological process 15843429 MGEA5 10724 meningioma expressed antigen 5 (hyaluronidase) positive regulation of proteolysis Biological process - TTLL5 23093 tubulin tyrosine ligase-like family member 5 cytoplasm Cellular component - WNT9B 7484 wingless-type MMTV integration site family, member 9B branching involved in ureteric bud morphogenesis Biological process - GCC2 9648 GRIP and coiled-coil domain containing 2 microtubule organizing center organization Biological process 17543864 TXLNG 55787 taxilin gamma cell cycle Biological process - S100A1 6271 S100 calcium binding protein A1 M band Cellular component - PSD2 84249 pleckstrin and Sec7 domain containing 2 vesicle-mediated transport Biological process - SLC5A6 8884 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 transmembrane transport Biological process - TAS2R1 50834 taste receptor, type 2, member 1 chemosensory behavior Biological process 10761934 NODAL 4838 nodal growth differentiation factor morphogen activity Molecular function 21159651 SH3BGRL3 83442 SH3 domain binding glutamate-rich protein like 3 protein disulfide oxidoreductase activity Molecular function - RAMP2 10266 receptor (G protein-coupled) activity modifying protein 2 sprouting angiogenesis Biological process - MBD2 8932 methyl-CpG binding domain protein 2 ATP-dependent chromatin remodeling Biological process 16217013 NODAL 4838 nodal growth differentiation factor placenta development Biological process 21356369 GTF2H1 2965 general transcription factor IIH, polypeptide 1, 62kDa gene expression Biological process - CDK5R1 8851 cyclin-dependent kinase 5, regulatory subunit 1 (p35) rhythmic process Biological process - FAM168B 130074 family with sequence similarity 168, member B plasma membrane Cellular component - AP2A2 161 adaptor-related protein complex 2, alpha 2 subunit clathrin-coated endocytic vesicle membrane Cellular component - TBCD 6904 tubulin folding cofactor D negative regulation of microtubule polymerization Biological process 10831612 RAB10 10890 RAB10, member RAS oncogene family GDP binding Molecular function 20937701 CD86 942 CD86 molecule epidermal growth factor receptor signaling pathway Biological process - PPP1R3F 89801 protein phosphatase 1, regulatory subunit 3F regulation of glycogen biosynthetic process Biological process 21668450 PKD2 5311 polycystic kidney disease 2 (autosomal dominant) regulation of calcium ion import Biological process 11854751 H3F3C 440093 H3 histone, family 3C protein heterodimerization activity Molecular function - ACVR1 90 activin A receptor, type I regulation of ossification Biological process 16642017 RAB14 51552 RAB14, member RAS oncogene family protein binding Molecular function 16034420 HSPB1 3315 heat shock 27kDa protein 1 protein kinase binding Molecular function 8774846 MID2 11043 midline 2 zinc ion binding Molecular function - GLRA4 441509 glycine receptor, alpha 4 cell junction Cellular component - TRAF2 7186 TNF receptor-associated factor 2 innate immune response Biological process - NKX3-1 4824 NK3 homeobox 1 positive regulation of response to DNA damage stimulus Biological process 20395202 IFIT1 3434 interferon-induced protein with tetratricopeptide repeats 1 cellular response to type I interferon Biological process 19008854 RAPSN 5913 receptor-associated protein of the synapse cytoplasm Cellular component - PSEN2 5664 presenilin 2 Golgi apparatus Cellular component 15274632 UGT3A1 133688 UDP glycosyltransferase 3 family, polypeptide A1 flavonoid biosynthetic process Biological process - RNF138 51444 ring finger protein 138, E3 ubiquitin protein ligase protein binding Molecular function 19549727 TYSND1 219743 trypsin domain containing 1 proteolysis Biological process 22002062 SRRM2 23524 serine/arginine repetitive matrix 2 Cajal body Cellular component 17577209 SRSF9 8683 serine/arginine-rich splicing factor 9 transcription from RNA polymerase II promoter Biological process - APP 351 amyloid beta (A4) precursor protein platelet alpha granule lumen Cellular component - POLQ 10721 polymerase (DNA directed), theta nucleoplasm Cellular component 10395804 PGR 5241 progesterone receptor RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 17785366 DPP8 54878 dipeptidyl-peptidase 8 membrane Cellular component - ZSCAN25 221785 zinc finger and SCAN domain containing 25 transcription, DNA-templated Biological process - SMAD4 4089 SMAD family member 4 SMAD protein signal transduction Biological process 9707553 TLR4 7099 toll-like receptor 4 positive regulation of JNK cascade Biological process - HOPX 84525 HOP homeobox negative regulation of transcription from RNA polymerase II promoter Biological process - ERCC5 2073 excision repair cross-complementation group 5 UV protection Biological process 7510366 SALL2 6297 spalt-like transcription factor 2 protein binding Molecular function 16189514 HECW2 57520 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 ubiquitin-protein transferase activity Molecular function - FOXA1 3169 forkhead box A1 nucleus Cellular component - SLC7A4 6545 solute carrier family 7, member 4 L-ornithine transmembrane transporter activity Molecular function - ZNF347 84671 zinc finger protein 347 DNA binding Molecular function - COL15A1 1306 collagen, type XV, alpha 1 collagen catabolic process Biological process - NFKBIL1 4795 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 negative regulation of NF-kappaB transcription factor activity Biological process 20829348 PVRIG 79037 poliovirus receptor related immunoglobulin domain containing integral component of membrane Cellular component - ING3 54556 inhibitor of growth family, member 3 chromatin organization Biological process - TXN 7295 thioredoxin cell redox homeostasis Biological process - PCCA 5095 propionyl CoA carboxylase, alpha polypeptide mitochondrial matrix Cellular component - DNAI1 27019 dynein, axonemal, intermediate chain 1 microtubule Cellular component - FOXC1 2296 forkhead box C1 sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function - EDNRB 1910 endothelin receptor type B cytosol Cellular component - APOBEC3G 60489 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G innate immune response Biological process 17121840 MPST 4357 mercaptopyruvate sulfurtransferase thiosulfate sulfurtransferase activity Molecular function - KRT25 147183 keratin 25, type I hair cycle Biological process 21916889 WDR5 11091 WD repeat domain 5 Ada2/Gcn5/Ada3 transcription activator complex Cellular component 18838386 Mar-01 55016 membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase endosome Cellular component 14722266 CDYL 9425 chromodomain protein, Y-like methylated histone binding Molecular function 18450745 CDK5RAP3 80279 CDK5 regulatory subunit associated protein 3 negative regulation of NF-kappaB transcription factor activity Biological process 17785205 CIRH1A 84916 cirrhosis, autosomal recessive 1A (cirhin) maturation of SSU-rRNA Biological process 22916032 RHOA 387 ras homolog family member A regulation of small GTPase mediated signal transduction Biological process - GBA2 57704 glucosidase, beta (bile acid) 2 glucosylceramidase activity Molecular function - GABRA6 2559 gamma-aminobutyric acid (GABA) A receptor, alpha 6 transport Biological process 8632757 ACOT2 10965 acyl-CoA thioesterase 2 acyl-CoA metabolic process Biological process 10944470 EIF2AK2 5610 eukaryotic translation initiation factor 2-alpha kinase 2 innate immune response Biological process - PSAP 5660 prosaposin extracellular exosome Cellular component 19056867 TUBB6 84617 tubulin, beta 6 class V extracellular exosome Cellular component 19056867 MGARP 84709 mitochondria-localized glutamic acid-rich protein mitochondrion Cellular component 16565373 CACNB1 782 calcium channel, voltage-dependent, beta 1 subunit axon guidance Biological process - ITPKC 80271 inositol-trisphosphate 3-kinase C calmodulin binding Molecular function - VTI1A 143187 vesicle transport through interaction with t-SNAREs 1A retrograde transport, endosome to Golgi Biological process 19224922 FOXP3 50943 forkhead box P3 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Molecular function - AOX1 316 aldehyde oxidase 1 vitamin metabolic process Biological process - ITCH 83737 itchy E3 ubiquitin protein ligase positive regulation of T cell anergy Biological process - FANCI 55215 Fanconi anemia, complementation group I cytoplasm Cellular component - PF4 5196 platelet factor 4 response to lipopolysaccharide Biological process - IKBKG 8517 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma mitotic spindle Cellular component 24561039 ATP2A3 489 ATPase, Ca++ transporting, ubiquitous sarcoplasmic reticulum Cellular component 8809064 CLN3 1201 ceroid-lipofuscinosis, neuronal 3 nucleus Cellular component 10191116 NOTCH4 4855 notch 4 receptor activity Molecular function 11823422 ABCA1 19 ATP-binding cassette, sub-family A (ABC1), member 1 receptor binding Molecular function 23931754 SORL1 6653 sortilin-related receptor, L(DLR class) A repeats containing negative regulation of protein binding Biological process 16407538 WNT5A 7474 wingless-type MMTV integration site family, member 5A urinary bladder development Biological process - NONO 4841 non-POU domain containing, octamer-binding mRNA processing Biological process - WDR62 284403 WD repeat domain 62 cytoplasm Cellular component - PIAS4 51588 protein inhibitor of activated STAT, 4 post-translational protein modification Biological process - KIAA1598 57698 KIAA1598 axon guidance Biological process - FERMT2 10979 fermitin family member 2 cell junction assembly Biological process - TNFRSF17 608 tumor necrosis factor receptor superfamily, member 17 integral component of membrane Cellular component - NUMA1 4926 nuclear mitotic apparatus protein 1 nucleoplasm Cellular component - KCTD4 386618 potassium channel tetramerization domain containing 4 protein homooligomerization Biological process - TP53 7157 tumor protein p53 T cell proliferation involved in immune response Biological process - RAB40C 57799 RAB40C, member RAS oncogene family intracellular protein transport Biological process - PES1 23481 pescadillo ribosomal biogenesis factor 1 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Biological process 16738141 RNF183 138065 ring finger protein 183 zinc ion binding Molecular function - SYT7 9066 synaptotagmin VII integral component of membrane Cellular component - APOB 338 apolipoprotein B positive regulation of lipid storage Biological process 18322245 KIF20A 10112 kinesin family member 20A ATPase activity Molecular function - HIPK1 204851 homeodomain interacting protein kinase 1 cytoplasm Cellular component 15701637 JCHAIN 3512 joining chain of multimeric IgA and IgM secretory IgA immunoglobulin complex Cellular component 23250751 SLFN12L 100506736 schlafen family member 12-like integral component of membrane Cellular component - BRCA2 675 breast cancer 2, early onset spermatogenesis Biological process - STX1A 6804 syntaxin 1A (brain) regulation of insulin secretion Biological process 15537656 MAPK1 5594 mitogen-activated protein kinase 1 regulation of early endosome to late endosome transport Biological process 19565474 SMAD3 4088 SMAD family member 3 lens fiber cell differentiation Biological process - SCAMP5 192683 secretory carrier membrane protein 5 protein transport Biological process - TYR 7299 tyrosinase oxidation-reduction process Biological process - OR4C5 79346 olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene) detection of chemical stimulus involved in sensory perception Biological process - ARSG 22901 arylsulfatase G arylsulfatase activity Molecular function 16174644 ATXN8 724066 ataxin 8 nucleus Cellular component - MAP2K5 5607 mitogen-activated protein kinase kinase 5 intracellular Cellular component - ALOX15B 247 arachidonate 15-lipoxygenase, type B negative regulation of cell proliferation Biological process 12704195 HMGA1 3159 high mobility group AT-hook 1 transcription, DNA-templated Biological process - ZP3 7784 zona pellucida glycoprotein 3 (sperm receptor) intracellular signal transduction Biological process 18667750 TINAGL1 64129 tubulointerstitial nephritis antigen-like 1 protein binding Molecular function 25416956 FMR1 2332 fragile X mental retardation 1 dendritic spine Cellular component - TAF3 83860 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa maintenance of protein location in nucleus Biological process 15870280 KIF11 3832 kinesin family member 11 ATP-dependent microtubule motor activity, plus-end-directed Molecular function - POLD4 57804 polymerase (DNA-directed), delta 4, accessory subunit DNA repair Biological process - ARHGAP8 23779 Rho GTPase activating protein 8 positive regulation of GTPase activity Biological process - KLF4 9314 Kruppel-like factor 4 (gut) post-embryonic camera-type eye development Biological process - HSPA1B 3304 heat shock 70kDa protein 1B positive regulation of IRE1-mediated unfolded protein response Biological process 20625543 CAV1 857 caveolin 1, caveolae protein, 22kDa patched binding Molecular function 11278759 ARAP1 116985 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 metal ion binding Molecular function - CELF3 11189 CUGBP, Elav-like family member 3 cytoplasm Cellular component 17725984 PLCB1 23236 phospholipase C, beta 1 (phosphoinositide-specific) positive regulation of myoblast differentiation Biological process - EDNRA 1909 endothelin receptor type A penile erection Biological process - UTP20 27340 UTP20, small subunit (SSU) processome component, homolog (yeast) nucleolus Cellular component 15590835 PTGES3 10728 prostaglandin E synthase 3 (cytosolic) prostaglandin-E synthase activity Molecular function 10922363 OR5M1 390168 olfactory receptor, family 5, subfamily M, member 1 integral component of plasma membrane Cellular component - TOP2A 7153 topoisomerase (DNA) II alpha 170kDa condensed chromosome Cellular component - OSGEPL1 64172 O-sialoglycoprotein endopeptidase-like 1 threonylcarbamoyladenosine biosynthetic process Biological process - RBM39 9584 RNA binding motif protein 39 poly(A) RNA binding Molecular function 22658674 NPC1 4864 Niemann-Pick disease, type C1 cholesterol homeostasis Biological process - SLC35F1 222553 solute carrier family 35, member F1 integral component of membrane Cellular component - CA3 761 carbonic anhydrase III response to oxidative stress Biological process - ASTL 431705 astacin-like metallo-endopeptidase (M12 family) metalloendopeptidase activity Molecular function 15087446 TROVE2 6738 TROVE domain family, member 2 ribonucleoprotein complex Cellular component 17289661 FADS3 3995 fatty acid desaturase 3 molecular_function Molecular function - SETD1A 9739 SET domain containing 1A nucleus Cellular component 22723415 ASS1 445 argininosuccinate synthase 1 midgut development Biological process - PSEN1 5663 presenilin 1 neuronal cell body Cellular component - CADM1 23705 cell adhesion molecule 1 synapse assembly Biological process - STX8 9482 syntaxin 8 protein binding Molecular function 25416956 SEC61B 10952 Sec61 beta subunit membrane Cellular component 22375059 OR52A5 390054 olfactory receptor, family 52, subfamily A, member 5 plasma membrane Cellular component - PCDH11Y 83259 protocadherin 11 Y-linked homophilic cell adhesion via plasma membrane adhesion molecules Biological process - TREML1 340205 triggering receptor expressed on myeloid cells-like 1 platelet alpha granule Cellular component - RPL22 6146 ribosomal protein L22 nucleus Cellular component 22720776 PNLIP 5406 pancreatic lipase positive regulation of triglyceride lipase activity Biological process 9631512 OSR1 130497 odd-skipped related transciption factor 1 transcription, DNA-templated Biological process - ARHGAP26 23092 Rho GTPase activating protein 26 regulation of small GTPase mediated signal transduction Biological process - IDS 3423 iduronate 2-sulfatase small molecule metabolic process Biological process - CHGA 1113 chromogranin A secretory granule Cellular component - DAG1 1605 dystroglycan 1 (dystrophin-associated glycoprotein 1) contractile ring Cellular component 18341635 CLU 1191 clusterin microglial cell proliferation Biological process 15857407 LPAL2 80350 lipoprotein, Lp(a)-like 2, pseudogene extracellular region Cellular component - SORL1 6653 sortilin-related receptor, L(DLR class) A repeats containing protein binding Molecular function 14764453 ERN1 2081 endoplasmic reticulum to nucleus signaling 1 regulation of transcription, DNA-templated Biological process - HACE1 57531 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 cell cycle Biological process - EDN1 1906 endothelin 1 cellular response to fatty acid Biological process - SPRTN 83932 SprT-like N-terminal domain translesion synthesis Biological process - CDC7 8317 cell division cycle 7 phagocytosis Biological process - BZW1 9689 basic leucine zipper and W2 domains 1 membrane Cellular component 19946888 FGD4 121512 FYVE, RhoGEF and PH domain containing 4 regulation of small GTPase mediated signal transduction Biological process - RRM2 6241 ribonucleotide reductase M2 mitotic cell cycle Biological process - ADRA2A 150 adrenoceptor alpha 2A fear response Biological process - ATP6V1C1 528 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 cytoplasmic vesicle Cellular component - CD81 975 CD81 molecule integral component of plasma membrane Cellular component 14676841 GJA1 2697 gap junction protein, alpha 1, 43kDa positive regulation of striated muscle tissue development Biological process - SPAG16 79582 sperm associated antigen 16 spermatogenesis Biological process - MBTPS2 51360 membrane-bound transcription factor peptidase, site 2 cytoplasm Cellular component 19361614 KDM5C 8242 lysine (K)-specific demethylase 5C rhythmic process Biological process - BTN2A2 10385 butyrophilin, subfamily 2, member A2 negative regulation of cytokine secretion Biological process - KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog Kit signaling pathway Biological process 17662946 COL1A2 1278 collagen, type I, alpha 2 identical protein binding Molecular function 17211858 TMPRSS11D 9407 transmembrane protease, serine 11D serine-type endopeptidase activity Molecular function - NCAPD2 9918 non-SMC condensin I complex, subunit D2 histone binding Molecular function 10958694 TAOK1 57551 TAO kinase 1 regulation of cytoskeleton organization Biological process - DRD2 1813 dopamine receptor D2 positive regulation of G-protein coupled receptor protein signaling pathway Biological process - AKAP10 11216 A kinase (PRKA) anchor protein 10 signal transduction Biological process 9326583 PRAMEF4 400735 PRAME family member 4 positive regulation of cell proliferation Biological process - TNFSF13 8741 tumor necrosis factor (ligand) superfamily, member 13 cytokine activity Molecular function - TUBB 203068 tubulin, beta class I microtubule-based process Biological process 12090300 IFT88 8100 intraflagellar transport 88 regulation of smoothened signaling pathway Biological process - IGKC 3514 immunoglobulin kappa constant immune response Biological process 6779204 PPP1R15A 23645 protein phosphatase 1, regulatory subunit 15A regulation of translational initiation by eIF2 alpha dephosphorylation Biological process 12556489 PDSS1 23590 prenyl (decaprenyl) diphosphate synthase, subunit 1 transferase complex Cellular component 16262699 MUTYH 4595 mutY homolog base-excision repair Biological process - BCL6 604 B-cell CLL/lymphoma 6 negative regulation of transcription, DNA-templated Biological process 9135990 CHD3 1107 chromodomain helicase DNA binding protein 3 nucleus Cellular component 9688266 ZNF830 91603 zinc finger protein 830 nuclear speck Cellular component - DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) positive regulation of proteasomal ubiquitin-dependent protein catabolic process Biological process 12805222 MED1 5469 mediator complex subunit 1 peroxisome proliferator activated receptor signaling pathway Biological process - GTF2H2 2966 general transcription factor IIH, polypeptide 2, 44kDa protein N-terminus binding Molecular function 8652557 MYO10 4651 myosin X actin-dependent ATPase activity Molecular function - NR4A2 4929 nuclear receptor subfamily 4, group A, member 2 regulation of dopamine metabolic process Biological process - YTHDC1 91746 YTH domain containing 1 mRNA splice site selection Biological process 20167602 PLSCR1 5359 phospholipid scramblase 1 enzyme binding Molecular function 12586838 SEC14L1 6397 SEC14-like 1 (S. cerevisiae) transport Biological process - PLA2G1B 5319 phospholipase A2, group IB (pancreas) extracellular space Cellular component 12860195 CASP6 839 caspase 6, apoptosis-related cysteine peptidase cysteine-type endopeptidase activity Molecular function - RASAL1 8437 RAS protein activator like 1 (GAP1 like) plasma membrane Cellular component 16009725 TICAM2 353376 toll-like receptor adaptor molecule 2 inflammatory response Biological process - CHPT1 56994 choline phosphotransferase 1 phosphatidylcholine biosynthetic process Biological process - ZNF639 51193 zinc finger protein 639 protein self-association Molecular function 20484494 ATP6V0A4 50617 ATPase, H+ transporting, lysosomal V0 subunit a4 transmembrane transport Biological process - TYR 7299 tyrosinase melanosome Cellular component - ARL8A 127829 ADP-ribosylation factor-like 8A chromosome segregation Biological process 14871887 AP2B1 163 adaptor-related protein complex 2, beta 1 subunit endocytic vesicle membrane Cellular component - PCID2 55795 PCI domain containing 2 spleen development Biological process - NPR3 4883 natriuretic peptide receptor 3 negative regulation of adenylate cyclase activity Biological process - RAMP2 10266 receptor (G protein-coupled) activity modifying protein 2 vascular smooth muscle cell development Biological process - HMGA2 8091 high mobility group AT-hook 2 protein binding Molecular function 16293633 TUBB3 10381 tubulin, beta 3 class III microtubule-based process Biological process - CCR7 1236 chemokine (C-C motif) receptor 7 plasma membrane Cellular component - ACSS3 79611 acyl-CoA synthetase short-chain family member 3 mitochondrion Cellular component - C1QB 713 complement component 1, q subcomponent, B chain protein binding Molecular function 12960167 TMEM192 201931 transmembrane protein 192 plasma membrane Cellular component 22736246 PSMA3 5684 proteasome (prosome, macropain) subunit, alpha type, 3 negative regulation of canonical Wnt signaling pathway Biological process - TARS2 80222 threonyl-tRNA synthetase 2, mitochondrial (putative) mitochondrial threonyl-tRNA aminoacylation Biological process 15779907 JAM3 83700 junctional adhesion molecule 3 protein heterodimerization activity Molecular function - LAMB1 3912 laminin, beta 1 negative regulation of cell adhesion Biological process - CYP11A1 1583 cytochrome P450, family 11, subfamily A, polypeptide 1 heme binding Molecular function 21636783 CLDN11 5010 claudin 11 identical protein binding Molecular function - AKT1 207 v-akt murine thymoma viral oncogene homolog 1 cellular response to organic cyclic compound Biological process - TNRC6C 57690 trinucleotide repeat containing 6C nucleotide binding Molecular function - MAPK15 225689 mitogen-activated protein kinase 15 positive regulation of protein phosphorylation Biological process - CLCA2 9635 chloride channel accessory 2 intracellular calcium activated chloride channel activity Molecular function - IMPG2 50939 interphotoreceptor matrix proteoglycan 2 extracellular matrix structural constituent Molecular function 10702256 CSGALNACT2 55454 chondroitin sulfate N-acetylgalactosaminyltransferase 2 carbohydrate metabolic process Biological process - USP14 9097 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) cytoplasm Cellular component - ZFPM1 161882 zinc finger protein, FOG family member 1 RNA polymerase II activating transcription factor binding Molecular function - ERGIC3 51614 ERGIC and golgi 3 integral component of membrane Cellular component - DRD2 1813 dopamine receptor D2 regulation of potassium ion transport Biological process - ALK 238 anaplastic lymphoma receptor tyrosine kinase transmembrane receptor protein tyrosine kinase activity Molecular function 19459784 POLR1C 9533 polymerase (RNA) I polypeptide C, 30kDa RNA polymerase III activity Molecular function - TGFB2 7042 transforming growth factor, beta 2 type III transforming growth factor beta receptor binding Molecular function 11157754 JAM3 83700 junctional adhesion molecule 3 Golgi apparatus Cellular component - KCNK16 83795 potassium channel, two pore domain subfamily K, member 16 potassium ion leak channel activity Molecular function - NUTF2 10204 nuclear transport factor 2 protein export from nucleus Biological process 16449645 PLVAP 83483 plasmalemma vesicle associated protein extracellular exosome Cellular component 18570454 CHIC1 53344 cysteine-rich hydrophobic domain 1 transport Biological process - ARPP19 10776 cAMP-regulated phosphoprotein, 19kDa dopamine receptor signaling pathway Biological process - NXF5 55998 nuclear RNA export factor 5 mRNA export from nucleus Biological process 11566096 SOX4 6659 SRY (sex determining region Y)-box 4 sequence-specific DNA binding transcription factor activity Molecular function 16631117 RUVBL2 10856 RuvB-like AAA ATPase 2 unfolded protein binding Molecular function 10524211 TP53 7157 tumor protein p53 enzyme binding Molecular function 10666337 SRF 6722 serum response factor (c-fos serum response element-binding transcription factor) cellular senescence Biological process 15282327 MSN 4478 moesin leukocyte cell-cell adhesion Biological process 12082081 SYT1 6857 synaptotagmin I identical protein binding Molecular function - POLR2E 5434 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa gene expression Biological process - USP44 84101 ubiquitin specific peptidase 44 nucleolus Cellular component - ABL1 25 ABL proto-oncogene 1, non-receptor tyrosine kinase positive regulation of mitotic cell cycle Biological process - NDUFAF3 25915 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 protein binding Molecular function 19463981 GRIP1 23426 glutamate receptor interacting protein 1 androgen receptor binding Molecular function 15572661 TMEM47 83604 transmembrane protein 47 integral component of membrane Cellular component - KDM6A 7403 lysine (K)-specific demethylase 6A notochord morphogenesis Biological process - RBX1 9978 ring-box 1, E3 ubiquitin protein ligase ubiquitin-ubiquitin ligase activity Molecular function 10230407 PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Biological process - FRAT2 23401 frequently rearranged in advanced T-cell lymphomas 2 cell proliferation Biological process 9635432 LDLRAD1 388633 low density lipoprotein receptor class A domain containing 1 integral component of membrane Cellular component - AGO2 27161 argonaute RISC catalytic component 2 siRNA binding Molecular function 15973356 CHMP6 79643 charged multivesicular body protein 6 endosomal transport Biological process - OFD1 8481 oral-facial-digital syndrome 1 G2/M transition of mitotic cell cycle Biological process - UIMC1 51720 ubiquitin interaction motif containing 1 negative regulation of transcription, DNA-templated Biological process 12080054 MARVELD2 153562 MARVEL domain containing 2 apical plasma membrane Cellular component 23073616 RHOB 388 ras homolog family member B late endosome membrane Cellular component - SYNE2 23224 spectrin repeat containing, nuclear envelope 2 actin filament binding Molecular function - LAP3 51056 leucine aminopeptidase 3 nucleoplasm Cellular component - PSCA 8000 prostate stem cell antigen plasma membrane Cellular component - MCM2 4171 minichromosome maintenance complex component 2 ATP binding Molecular function - APIP 51074 APAF1 interacting protein L-methionine biosynthetic process from S-adenosylmethionine Biological process - AGBL4 84871 ATP/GTP binding protein-like 4 ciliary basal body Cellular component 23085998 ABCB6 10058 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) transmembrane transport Biological process - CASP1 834 caspase 1, apoptosis-related cysteine peptidase cellular response to mechanical stimulus Biological process 19593445 MAPK3 5595 mitogen-activated protein kinase 3 toll-like receptor 3 signaling pathway Biological process - THEM4 117145 thioesterase superfamily member 4 fibroblast growth factor receptor signaling pathway Biological process - CCZ1 51622 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) lysosomal membrane Cellular component - MAPK14 1432 mitogen-activated protein kinase 14 ATP binding Molecular function - PSME2 5721 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) membrane Cellular component 19946888 UBE2L6 9246 ubiquitin-conjugating enzyme E2L 6 ligase activity Molecular function - GSK3B 2932 glycogen synthase kinase 3 beta positive regulation of peptidyl-serine phosphorylation Biological process - SPAST 6683 spastin microtubule Cellular component - ZNF644 84146 zinc finger protein 644 transcription, DNA-templated Biological process - SEC24D 9871 SEC24 family member D cellular protein metabolic process Biological process - SLC38A1 81539 solute carrier family 38, member 1 transmembrane transport Biological process - DNAAF2 55172 dynein, axonemal, assembly factor 2 bacterial-type flagellum-dependent cell motility Biological process 19052621 HIVEP2 3097 human immunodeficiency virus type I enhancer binding protein 2 transcription, DNA-templated Biological process - PINK1 65018 PTEN induced putative kinase 1 positive regulation of sequence-specific DNA binding transcription factor activity Biological process - FANCG 2189 Fanconi anemia, complementation group G protein binding Molecular function 10627486 STRA13 201254 stimulated by retinoic acid 13 resolution of meiotic recombination intermediates Biological process 20347428 TRPM4 54795 transient receptor potential cation channel, subfamily M, member 4 regulation of membrane potential Biological process - PIK3R1 5295 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Fc-gamma receptor signaling pathway involved in phagocytosis Biological process - ZBTB16 7704 zinc finger and BTB domain containing 16 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function 12802276 TM7SF3 51768 transmembrane 7 superfamily member 3 plasma membrane Cellular component - OXCT1 5019 3-oxoacid CoA transferase 1 cellular lipid metabolic process Biological process - NRXN2 9379 neurexin 2 cell Cellular component - BMP7 655 bone morphogenetic protein 7 negative regulation of striated muscle cell apoptotic process Biological process - PTK7 5754 protein tyrosine kinase 7 (inactive) positive regulation of neuron projection development Biological process 17910947 BMP10 27302 bone morphogenetic protein 10 ventricular cardiac muscle tissue morphogenesis Biological process 10072785 APC 324 adenomatous polyposis coli protein complex assembly Biological process 16188939 ACSL4 2182 acyl-CoA synthetase long-chain family member 4 neuronal cell body Cellular component - PTEN 5728 phosphatase and tensin homolog negative regulation of focal adhesion assembly Biological process 9616126 CTAGE4 100128553 CTAGE family, member 4 biological_process Biological process - KLHL22 84861 kelch-like family member 22 mitotic spindle Cellular component 23455478 S100A13 6284 S100 calcium binding protein A13 zinc ion binding Molecular function 12118070 KIF13B 23303 kinesin family member 13B microtubule Cellular component - TNKS2 80351 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 enzyme binding Molecular function 21251231 ABL1 25 ABL proto-oncogene 1, non-receptor tyrosine kinase B cell proliferation involved in immune response Biological process - E2F7 144455 E2F transcription factor 7 sequence-specific DNA binding transcription factor activity Molecular function 22903062 FMOD 2331 fibromodulin keratan sulfate biosynthetic process Biological process - CD99 4267 CD99 molecule integral component of plasma membrane Cellular component 2465491 GHRHR 2692 growth hormone releasing hormone receptor plasma membrane Cellular component - FOXP3 50943 forkhead box P3 cytoplasm Cellular component 16903909 CHAF1A 10036 chromatin assembly factor 1, subunit A (p150) unfolded protein binding Molecular function 7600578 SLC34A2 10568 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 ion transport Biological process - ACAD11 84129 acyl-CoA dehydrogenase family, member 11 peroxisome Cellular component - TRIM74 378108 tripartite motif containing 74 protein binding Molecular function 25416956 SMR3B 10879 submaxillary gland androgen regulated protein 3B protein binding Molecular function 25416956 APH1A 51107 APH1A gamma secretase subunit axon guidance Biological process - DRAXIN 374946 dorsal inhibitory axon guidance protein negative regulation of neuron apoptotic process Biological process - MYCN 4613 v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog positive regulation of transcription from RNA polymerase II promoter Biological process - TBX3 6926 T-box 3 negative regulation of transcription from RNA polymerase II promoter Biological process 11689487 HPS6 79803 Hermansky-Pudlak syndrome 6 protein localization to membrane Biological process 22511774 FABP6 2172 fatty acid binding protein 6, ileal lipid binding Molecular function - SLC9A8 23315 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 hydrogen ion transmembrane transport Biological process - CCR4 1233 chemokine (C-C motif) receptor 4 cytosol Cellular component 7642634 PPP1R1B 84152 protein phosphatase 1, regulatory (inhibitor) subunit 1B regulation of catalytic activity Biological process - TCF3 6929 transcription factor 3 nucleus Cellular component 2493990 IDE 3416 insulin-degrading enzyme mitochondrion Cellular component 15285718 BRCA1 672 breast cancer 1, early onset negative regulation of fatty acid biosynthetic process Biological process 16326698 ACTL7A 10881 actin-like 7A nucleus Cellular component 21630459 PAX6 5080 paired box 6 insulin metabolic process Biological process - TERT 7015 telomerase reverse transcriptase negative regulation of gene expression Biological process 11927518 SATB2 23314 SATB homeobox 2 protein binding Molecular function 20829881 SLC25A40 55972 solute carrier family 25, member 40 integral component of membrane Cellular component - CATSPER2 117155 cation channel, sperm associated 2 multicellular organism reproduction Biological process - THBS1 7057 thrombospondin 1 phosphatidylserine binding Molecular function 18940719 TXNIP 10628 thioredoxin interacting protein cytosol Cellular component - EDF1 8721 endothelial differentiation-related factor 1 nucleolus Cellular component - PYCRL 65263 pyrroline-5-carboxylate reductase-like protein binding Molecular function 25416956 TNFRSF8 943 tumor necrosis factor receptor superfamily, member 8 transmembrane signaling receptor activity Molecular function - ACTN1 87 actinin, alpha 1 calcium ion binding Molecular function - AMBP 259 alpha-1-microglobulin/bikunin precursor female pregnancy Biological process 10097787 EXOC1 55763 exocyst complex component 1 plasma membrane Cellular component - CD302 9936 CD302 molecule phagocytosis Biological process 17947679 HLA-G 3135 major histocompatibility complex, class I, G early endosome membrane Cellular component - FGF10 2255 fibroblast growth factor 10 embryonic digestive tract morphogenesis Biological process - VAMP1 6843 vesicle-associated membrane protein 1 (synaptobrevin 1) cell surface Cellular component - SOX15 6665 SRY (sex determining region Y)-box 15 positive regulation of G0 to G1 transition Biological process 17363903 TLR4 7099 toll-like receptor 4 positive regulation of transcription from RNA polymerase II promoter Biological process - RAD1 5810 RAD1 checkpoint DNA exonuclease nucleoplasm Cellular component - TRIM24 8805 tripartite motif containing 24 methylated histone binding Molecular function 21164480 PLA2G4B 100137049 phospholipase A2, group IVB (cytosolic) extracellular region Cellular component 10085124 SATB2 23314 SATB homeobox 2 cytoplasm Cellular component - FGD3 89846 FYVE, RhoGEF and PH domain containing 3 ruffle Cellular component - SNRPE 6635 small nuclear ribonucleoprotein polypeptide E SMN-Sm protein complex Cellular component 18984161 SLC16A14 151473 solute carrier family 16, member 14 plasma membrane Cellular component - RBSN 64145 rabenosyn, RAB effector endocytosis Biological process - BAIAP2L1 55971 BAI1-associated protein 2-like 1 actin crosslink formation Biological process - CA3 761 carbonic anhydrase III small molecule metabolic process Biological process - RBP2 5948 retinol binding protein 2, cellular retinal binding Molecular function - GFI1B 8328 growth factor independent 1B transcription repressor cell proliferation Biological process 9566867 CAMK2B 816 calcium/calmodulin-dependent protein kinase II beta inhibitory G-protein coupled receptor phosphorylation Biological process - FOXI3 344167 forkhead box I3 transcription, DNA-templated Biological process - MTOR 2475 mechanistic target of rapamycin (serine/threonine kinase) protein serine/threonine kinase activity Molecular function - PTX3 5806 pentraxin 3, long negative regulation of exo-alpha-sialidase activity Biological process 23544079 PDLIM1 9124 PDZ and LIM domain 1 focal adhesion Cellular component 21423176 IKBKB 3551 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta scaffold protein binding Molecular function 23776175 CEP170B 283638 centrosomal protein 170B microtubule Cellular component - HLF 3131 hepatic leukemia factor sequence-specific DNA binding transcription factor activity Molecular function - SLC22A1 6580 solute carrier family 22 (organic cation transporter), member 1 ammonium transmembrane transport Biological process - F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 positive regulation of chemotaxis Biological process - RTN4IP1 84816 reticulon 4 interacting protein 1 oxidation-reduction process Biological process - CCNE2 9134 cyclin E2 protein binding Molecular function 15232106 CTDSP1 58190 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 negative regulation of neuron differentiation Biological process - HAL 3034 histidine ammonia-lyase cytosol Cellular component - H2AFY 9555 H2A histone family, member Y nucleosomal DNA binding Molecular function - SERPINA3 12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 protein binding Molecular function 12709365 SUCNR1 56670 succinate receptor 1 integral component of membrane Cellular component - TAAR6 319100 trace amine associated receptor 6 sensory perception of chemical stimulus Biological process - ZNRF3 84133 zinc and ring finger 3 ubiquitin-protein transferase activity Molecular function 22575959 CDK5 1020 cyclin-dependent kinase 5 neuron differentiation Biological process 21473899 TSPY4 728395 testis specific protein, Y-linked 4 cell differentiation Biological process - PSMB8 5696 proteasome (prosome, macropain) subunit, beta type, 8 regulation of apoptotic process Biological process - FABP6 2172 fatty acid binding protein 6, ileal transporter activity Molecular function - RPS27A 6233 ribosomal protein S27a apoptotic process Biological process - DDX11 1663 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 helicase activity Molecular function 18499658 PPP2CA 5515 protein phosphatase 2, catalytic subunit, alpha isozyme regulation of growth Biological process 11360189 SMARCAD1 56916 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 protein homooligomerization Biological process 11031099 C10orf2 56652 chromosome 10 open reading frame 2 mitochondrial nucleoid Cellular component 18063578 DEFB108B 245911 defensin, beta 108B innate immune response Biological process - DDX5 1655 DEAD (Asp-Glu-Ala-Asp) box helicase 5 circadian rhythm Biological process - NRXN1 9378 neurexin 1 adult behavior Biological process 17034946 GMEB2 26205 glucocorticoid modulatory element binding protein 2 metal ion binding Molecular function - SIAH1 6477 siah E3 ubiquitin protein ligase 1 positive regulation of apoptotic process Biological process 21185211 GPC5 2262 glypican 5 integral component of plasma membrane Cellular component 7657705 RAET1E 135250 retinoic acid early transcript 1E T cell mediated cytotoxicity Biological process - FDXR 2232 ferredoxin reductase steroid metabolic process Biological process - PNLIPRP2 5408 pancreatic lipase-related protein 2 extracellular space Cellular component 18702514 CMKLR1 1240 chemerin chemokine-like receptor 1 positive regulation of fat cell differentiation Biological process - PIK3R1 5295 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) plasma membrane Cellular component - HIST3H3 8290 histone cluster 3, H3 nucleosome assembly Biological process 20498094 CCS 9973 copper chaperone for superoxide dismutase zinc ion binding Molecular function - RPL22 6146 ribosomal protein L22 translational elongation Biological process - TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) positive regulation of cell proliferation Biological process 17525748 USF1 7391 upstream transcription factor 1 sequence-specific DNA binding Molecular function 2249772 CYP4B1 1580 cytochrome P450, family 4, subfamily B, polypeptide 1 small molecule metabolic process Biological process - CLK3 1198 CDC-like kinase 3 intermediate filament cytoskeleton Cellular component - RAB38 23682 RAB38, member RAS oncogene family AP-3 adaptor complex binding Molecular function 22511774 SKOR2 652991 SKI family transcriptional corepressor 2 cytoplasm Cellular component 16200078 MRPL42 28977 mitochondrial ribosomal protein L42 mitochondrial translational termination Biological process - ENPP1 5167 ectonucleotide pyrophosphatase/phosphodiesterase 1 zinc ion binding Molecular function - STX4 6810 syntaxin 4 dendritic spine Cellular component 20434989 ARHGAP10 79658 Rho GTPase activating protein 10 positive regulation of GTPase activity Biological process - ALAS1 211 5'-aminolevulinate synthase 1 mitochondrial matrix Cellular component - GCGR 2642 glucagon receptor cellular response to glucagon stimulus Biological process - ZKSCAN3 80317 zinc finger with KRAB and SCAN domains 3 cytoplasm Cellular component 23434374 PRKAA1 5562 protein kinase, AMP-activated, alpha 1 catalytic subunit response to hypoxia Biological process 8557660 CARTPT 9607 CART prepropeptide negative regulation of glucagon secretion Biological process - TENM4 26011 teneurin transmembrane protein 4 positive regulation of gastrulation Biological process - UNC13B 10497 unc-13 homolog B (C. elegans) cytoplasm Cellular component 10233166 IHH 3549 indian hedgehog extracellular space Cellular component - CHRNA4 1137 cholinergic receptor, nicotinic, alpha 4 (neuronal) regulation of inhibitory postsynaptic membrane potential Biological process - ZAN 7455 zonadhesin (gene/pseudogene) integral component of membrane Cellular component - OSTC 58505 oligosaccharyltransferase complex subunit (non-catalytic) protein binding Molecular function 25416956 UBC 7316 ubiquitin C G2/M transition of mitotic cell cycle Biological process - PLXNA2 5362 plexin A2 regulation of cell migration Biological process - CEP164 22897 centrosomal protein 164kDa protein binding Molecular function 22863007 DDX3X 1654 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked CTPase activity Molecular function 10074132 SPACA3 124912 sperm acrosome associated 3 extracellular region Cellular component 16150577 IGHMBP2 3508 immunoglobulin mu binding protein 2 DNA replication Biological process 8493094 GATA4 2626 GATA binding protein 4 RNA polymerase II transcription factor complex Cellular component 9312027 ABCB9 23457 ATP-binding cassette, sub-family B (MDR/TAP), member 9 integral component of endoplasmic reticulum membrane Cellular component 11011155 POTEF 728378 POTE ankyrin domain family, member F retina homeostasis Biological process 23580065 PLA2G4E 123745 phospholipase A2, group IVE phosphatidylinositol acyl-chain remodeling Biological process - SIX2 10736 SIX homeobox 2 anatomical structure morphogenesis Biological process 10773454 DYX1C1 161582 dyslexia susceptibility 1 candidate 1 outer dynein arm assembly Biological process 23872636 WNT5B 81029 wingless-type MMTV integration site family, member 5B proteinaceous extracellular matrix Cellular component - SCPEP1 59342 serine carboxypeptidase 1 serine-type carboxypeptidase activity Molecular function - TH 7054 tyrosine hydroxylase phytoalexin metabolic process Biological process - PIGQ 9091 phosphatidylinositol glycan anchor biosynthesis, class Q integral component of membrane Cellular component - RBBP4 5928 retinoblastoma binding protein 4 chromatin organization Biological process - PSMB7 5695 proteasome (prosome, macropain) subunit, beta type, 7 regulation of apoptotic process Biological process - PTPMT1 114971 protein tyrosine phosphatase, mitochondrial 1 inositol phosphate dephosphorylation Biological process - TICAM2 353376 toll-like receptor adaptor molecule 2 innate immune response Biological process - ATP6V0E2 155066 ATPase, H+ transporting V0 subunit e2 transferrin transport Biological process - MAP1LC3A 84557 microtubule-associated protein 1 light chain 3 alpha autophagosome Cellular component 12740394 CDC20 991 cell division cycle 20 cell cycle Biological process 9682218 ACTC1 70 actin, alpha, cardiac muscle 1 muscle filament sliding Biological process - ACD 65057 adrenocortical dysplasia homolog (mouse) nucleoplasm Cellular component - FIGNL1 63979 fidgetin-like 1 extracellular exosome Cellular component 19056867 PPP2R2A 5520 protein phosphatase 2, regulatory subunit B, alpha gene expression Biological process - OR3A2 4995 olfactory receptor, family 3, subfamily A, member 2 olfactory receptor activity Molecular function - E4F1 1877 E4F transcription factor 1 metal ion binding Molecular function - CCND3 896 cyclin D3 signal transduction Biological process - SPTLC1 10558 serine palmitoyltransferase, long chain base subunit 1 pyridoxal phosphate binding Molecular function - CAPZA1 829 capping protein (actin filament) muscle Z-line, alpha 1 barbed-end actin filament capping Biological process - ADGRE5 976 adhesion G protein-coupled receptor E5 protein binding Molecular function 9064337 CFC1 55997 cripto, FRL-1, cryptic family 1 anchored component of membrane Cellular component - ARID1A 8289 AT rich interactive domain 1A (SWI-like) SWI/SNF complex Cellular component 11078522 XYLT1 64131 xylosyltransferase I glycosaminoglycan biosynthetic process Biological process 11099377 CTTN 2017 cortactin actin cytoskeleton reorganization Biological process - UGT1A8 54576 UDP glucuronosyltransferase 1 family, polypeptide A8 fatty acid metabolic process Biological process 20610558 FXR1 8087 fragile X mental retardation, autosomal homolog 1 membrane Cellular component 19946888 PPFIBP1 8496 PTPRF interacting protein, binding protein 1 (liprin beta 1) focal adhesion Cellular component 21423176 OGDH 4967 oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) chaperone binding Molecular function - CBS 875 cystathionine-beta-synthase nucleolus Cellular component - ABHD12 26090 abhydrolase domain containing 12 integral component of membrane Cellular component - BIRC2 329 baculoviral IAP repeat containing 2 regulation of nucleotide-binding oligomerization domain containing signaling pathway Biological process 20888210 STX3 6809 syntaxin 3 endomembrane system Cellular component - TCP1 6950 t-complex 1 'de novo' posttranslational protein folding Biological process - PLAG1 5324 pleiomorphic adenoma gene 1 negative regulation of gene expression Biological process - OBSCN 84033 obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF M band Cellular component 11717165 PROX1 5629 prospero homeobox 1 kidney development Biological process 8812486 ABCC10 89845 ATP-binding cassette, sub-family C (CFTR/MRP), member 10 lysosomal membrane Cellular component 17897319 SLC25A41 284427 solute carrier family 25, member 41 mitochondrial inner membrane Cellular component - ARHGDIB 397 Rho GDP dissociation inhibitor (GDI) beta Rho protein signal transduction Biological process 8356058 TSPAN33 340348 tetraspanin 33 integral component of membrane Cellular component - KCTD10 83892 potassium channel tetramerization domain containing 10 ubiquitin-protein transferase activity Molecular function - RXFP3 51289 relaxin/insulin-like family peptide receptor 3 plasma membrane Cellular component - CCNK 8812 cyclin K cyclin-dependent protein serine/threonine kinase activity Molecular function 9632813 NR1D1 9572 nuclear receptor subfamily 1, group D, member 1 dendrite Cellular component - SLC22A16 85413 solute carrier family 22 (organic cation/carnitine transporter), member 16 integral component of membrane Cellular component 12089149 SNRPD2 6633 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa spliceosomal complex assembly Biological process 7527560 ARHGEF3 50650 Rho guanine nucleotide exchange factor (GEF) 3 neurotrophin TRK receptor signaling pathway Biological process - ORMDL2 29095 ORMDL sphingolipid biosynthesis regulator 2 ceramide metabolic process Biological process 20182505 TAF5 6877 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa protein binding Molecular function 15899866 ADH5 128 alcohol dehydrogenase 5 (class III), chi polypeptide ethanol catabolic process Biological process - RAB15 376267 RAB15, member RAS oncogene family Rab protein signal transduction Biological process - S1PR1 1901 sphingosine-1-phosphate receptor 1 transmission of nerve impulse Biological process - PGR 5241 progesterone receptor regulation of epithelial cell proliferation Biological process - MYH8 4626 myosin, heavy chain 8, skeletal muscle, perinatal cytoplasm Cellular component 21370490 ODF4 146852 outer dense fiber of sperm tails 4 multicellular organismal development Biological process - UNC45A 55898 unc-45 homolog A (C. elegans) muscle organ development Biological process - KLF9 687 Kruppel-like factor 9 DNA binding Molecular function - LRRC4 64101 leucine rich repeat containing 4 postsynaptic membrane Cellular component - LIMK1 3984 LIM domain kinase 1 protein phosphorylation Biological process 23633677 SLC26A6 65010 solute carrier family 26 (anion exchanger), member 6 intracellular Cellular component 15990874 TSACC 128229 TSSK6 activating co-chaperone protein binding Molecular function 25416956 DMRTA2 63950 DMRT-like family A2 cerebral cortex regionalization Biological process - PPP2R1A 5518 protein phosphatase 2, regulatory subunit A, alpha extracellular exosome Cellular component 23533145 SAMHD1 25939 SAM domain and HD domain 1 defense response to virus Biological process 19525956 PPOX 5498 protoporphyrinogen oxidase oxygen-dependent protoporphyrinogen oxidase activity Molecular function - MADD 8567 MAP-kinase activating death domain negative regulation of apoptotic signaling pathway Biological process - PELI3 246330 pellino E3 ubiquitin protein ligase family member 3 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway Biological process - STARD10 10809 StAR-related lipid transfer (START) domain containing 10 bile acid secretion Biological process - EEF2 1938 eukaryotic translation elongation factor 2 plasma membrane Cellular component - SART1 9092 squamous cell carcinoma antigen recognized by T cells mRNA cis splicing, via spliceosome Biological process - NGFR 4804 nerve growth factor receptor cell surface Cellular component - CARNS1 57571 carnosine synthase 1 ATP binding Molecular function - PAFAH1B1 5048 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) kinesin complex Cellular component - PF4V1 5197 platelet factor 4 variant 1 immune response Biological process - SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) regulation of excitatory postsynaptic membrane potential Biological process - TCF3 6929 transcription factor 3 regulation of transcription, DNA-templated Biological process 2493990 CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta nucleoplasm Cellular component - MAP3K14 9020 mitogen-activated protein kinase kinase kinase 14 regulation of mitotic cell cycle Biological process - VAMP2 6844 vesicle-associated membrane protein 2 (synaptobrevin 2) intracellular membrane-bounded organelle Cellular component - RHOQ 23433 ras homolog family member Q GTP binding Molecular function - ICAM1 3383 intercellular adhesion molecule 1 extracellular exosome Cellular component 19056867 PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 apoptotic process Biological process - RHOA 387 ras homolog family member A endosome Cellular component 19887681 TNIP2 79155 TNFAIP3 interacting protein 2 cellular response to lipopolysaccharide Biological process - CFAP52 146845 cilia and flagella associated protein 52 cytoplasm Cellular component - GDF6 392255 growth differentiation factor 6 pathway-restricted SMAD protein phosphorylation Biological process 16049014 NT5C 30833 5', 3'-nucleotidase, cytosolic purine nucleotide catabolic process Biological process - CIITA 4261 class II, major histocompatibility complex, transactivator GTP binding Molecular function - ZNF91 7644 zinc finger protein 91 zinc ion binding Molecular function 8467795 IFNG 3458 interferon, gamma positive regulation of interleukin-23 production Biological process 20027291 EXOSC4 54512 exosome component 4 AU-rich element binding Molecular function 16912217 SIRT2 22933 sirtuin 2 cellular response to caloric restriction Biological process - C8B 732 complement component 8, beta polypeptide immune response Biological process 8098723 SLC38A7 55238 solute carrier family 38, member 7 L-amino acid transmembrane transporter activity Molecular function - CASP1 834 caspase 1, apoptosis-related cysteine peptidase positive regulation of interleukin-1 beta secretion Biological process - RC3H1 149041 ring finger and CCCH-type domains 1 negative regulation of activated T cell proliferation Biological process - TRPM4 54795 transient receptor potential cation channel, subfamily M, member 4 cardiac conduction Biological process - ATP6V1C1 528 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 lysosomal membrane Cellular component 17897319 USF1 7391 upstream transcription factor 1 response to UV Biological process - OR56A1 120796 olfactory receptor, family 56, subfamily A, member 1 adenylate cyclase-activating adrenergic receptor signaling pathway Biological process - CHST2 9435 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 multicellular organismal development Biological process 9722682 GSK3B 2932 glycogen synthase kinase 3 beta negative regulation of glycogen (starch) synthase activity Biological process 19366350 PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 proteasome complex Cellular component 17323924 CLCF1 23529 cardiotrophin-like cytokine factor 1 B cell differentiation Biological process - NFKB2 4791 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) positive regulation of transcription from RNA polymerase II promoter Biological process 12835724 S1PR2 9294 sphingosine-1-phosphate receptor 2 integral component of membrane Cellular component - EPB41L3 23136 erythrocyte membrane protein band 4.1-like 3 paranode region of axon Cellular component - E4F1 1877 E4F transcription factor 1 cAMP response element binding Molecular function 14645522 INPP1 3628 inositol polyphosphate-1-phosphatase small molecule metabolic process Biological process - HIST1H3B 8358 histone cluster 1, H3b DNA replication-dependent nucleosome assembly Biological process 14718166 COMMD7 149951 COMM domain containing 7 cytoplasmic membrane-bounded vesicle Cellular component - IGKV4-1 28908 immunoglobulin kappa variable 4-1 innate immune response Biological process - CERS1 10715 ceramide synthase 1 intracellular membrane-bounded organelle Cellular component - PFKM 5213 phosphofructokinase, muscle 6-phosphofructokinase complex Cellular component 6444532 TYMS 7298 thymidylate synthetase organ regeneration Biological process - DNAH12 201625 dynein, axonemal, heavy chain 12 microtubule motor activity Molecular function - WWOX 51741 WW domain containing oxidoreductase RNA polymerase II transcription factor complex Cellular component 19366691 ACVR2B 93 activin A receptor, type IIB receptor complex Cellular component 9872992 SERPINE1 5054 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 extracellular matrix organization Biological process - GRIN1 2902 glutamate receptor, ionotropic, N-methyl D-aspartate 1 regulation of respiratory gaseous exchange Biological process - HDAC2 3066 histone deacetylase 2 deacetylase activity Molecular function - PHOSPHO2 493911 phosphatase, orphan 2 dephosphorylation Biological process - ZNF669 79862 zinc finger protein 669 regulation of transcription, DNA-templated Biological process - RILPL2 196383 Rab interacting lysosomal protein-like 2 cytosol Cellular component - SYF2 25949 SYF2 pre-mRNA-splicing factor poly(A) RNA binding Molecular function 22658674 CABIN1 23523 calcineurin binding protein 1 DNA replication-independent nucleosome assembly Biological process 14718166 CFLAR 8837 CASP8 and FADD-like apoptosis regulator death receptor binding Molecular function - VARS 7407 valyl-tRNA synthetase valine-tRNA ligase activity Molecular function 8428657 PENK 5179 proenkephalin neuropeptide hormone activity Molecular function 7057924 RAB3D 9545 RAB3D, member RAS oncogene family synaptic vesicle Cellular component - DIXDC1 85458 DIX domain containing 1 axon terminus Cellular component - PROX1 5629 prospero homeobox 1 ventricular cardiac muscle tissue morphogenesis Biological process - GRK5 2869 G protein-coupled receptor kinase 5 nuclear membrane Cellular component - SLC11A2 4891 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 zinc ion binding Molecular function - HADHB 3032 hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit poly(A) RNA binding Molecular function 22658674 MYCL 4610 v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog regulation of transcription, DNA-templated Biological process - ZNF703 80139 zinc finger protein 703 adherens junction assembly Biological process - RBM15B 29890 RNA binding motif protein 15B nucleoplasm Cellular component - H6PD 9563 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) glucose-6-phosphate dehydrogenase activity Molecular function - HOPX 84525 HOP homeobox negative regulation of cell differentiation Biological process 17576768 SRP9 6726 signal recognition particle 9kDa translation Biological process - BEGAIN 57596 brain-enriched guanylate kinase-associated membrane Cellular component - RPL14 9045 ribosomal protein L14 extracellular exosome Cellular component 20458337 OVCH1 341350 ovochymase 1 metal ion binding Molecular function - CDC42BPG 55561 CDC42 binding protein kinase gamma (DMPK-like) cell leading edge Cellular component 15194684 DDX1 1653 DEAD (Asp-Glu-Ala-Asp) box helicase 1 protein binding Molecular function 11598190 NCS1 23413 neuronal calcium sensor 1 calcium ion transmembrane transport Biological process - BHLHB9 80823 basic helix-loop-helix domain containing, class B, 9 negative regulation of neuron apoptotic process Biological process - HRC 3270 histidine rich calcium binding protein ATPase binding Molecular function 17526652 FMO1 2326 flavin containing monooxygenase 1 toxin metabolic process Biological process 15144220 BLNK 29760 B-cell linker plasma membrane Cellular component - LEFTY1 10637 left-right determination factor 1 transforming growth factor beta receptor binding Molecular function - SH3GLB1 51100 SH3-domain GRB2-like endophilin B1 mitochondrial outer membrane Cellular component - SLC5A7 60482 solute carrier family 5 (sodium/choline cotransporter), member 7 neurotransmitter secretion Biological process - TMEM147 10430 transmembrane protein 147 integral component of membrane Cellular component - APP 351 amyloid beta (A4) precursor protein mRNA polyadenylation Biological process - JUN 3725 jun proto-oncogene membrane depolarization Biological process - PPP1R2P1 100507444 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1 negative regulation of catalytic activity Biological process - CCDC174 51244 coiled-coil domain containing 174 nucleoplasm Cellular component - DBI 1622 diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) long-chain fatty acyl-CoA binding Molecular function 21079819 STX7 8417 syntaxin 7 vesicle docking Biological process - VAT1 10493 vesicle amine transport 1 mitochondrial outer membrane Cellular component - CXCL13 10563 chemokine (C-X-C motif) ligand 13 activation of GTPase activity Biological process - MID2 11043 midline 2 protein homodimerization activity Molecular function 11806752 TCTE3 6991 t-complex-associated-testis-expressed 3 transport Biological process - SETDB1 9869 SET domain, bifurcated 1 negative regulation of transcription from RNA polymerase II promoter Biological process - TINAGL1 64129 tubulointerstitial nephritis antigen-like 1 scavenger receptor activity Molecular function - APH1A 51107 APH1A gamma secretase subunit protein binding Molecular function 12297508 CST8 10047 cystatin 8 (cystatin-related epididymal specific) cytoplasm Cellular component - HNRNPM 4670 heterogeneous nuclear ribonucleoprotein M nucleolus Cellular component - SPP1 6696 secreted phosphoprotein 1 extracellular matrix disassembly Biological process - PPP1R7 5510 protein phosphatase 1, regulatory subunit 7 protein binding Molecular function 25416956 TOPBP1 11073 topoisomerase (DNA) II binding protein 1 condensed nuclear chromosome Cellular component - UBR5 51366 ubiquitin protein ligase E3 component n-recognin 5 positive regulation of catenin import into nucleus Biological process 21118991 FGF20 26281 fibroblast growth factor 20 cell-cell signaling Biological process 10913340 GRHL2 79977 grainyhead-like 2 (Drosophila) cell junction assembly Biological process 25152456 MYB 4602 v-myb avian myeloblastosis viral oncogene homolog positive regulation of transcription from RNA polymerase II promoter Biological process 20531406 ETF1 2107 eukaryotic translation termination factor 1 translational termination Biological process - ARSH 347527 arylsulfatase family, member H endoplasmic reticulum lumen Cellular component - P2RX7 5027 purinergic receptor P2X, ligand gated ion channel, 7 positive regulation of interleukin-1 beta secretion Biological process 17036048 SEZ6L2 26470 seizure related 6 homolog (mouse)-like 2 integral component of membrane Cellular component - CWC27 10283 CWC27 spliceosome-associated protein homolog (S. cerevisiae) mRNA splicing, via spliceosome Biological process 11991638 PIWIL2 55124 piwi-like RNA-mediated gene silencing 2 RNA 5'-end processing Biological process - UNC50 25972 unc-50 homolog (C. elegans) protein transport Biological process - SCARB1 949 scavenger receptor class B, member 1 1-phosphatidylinositol binding Molecular function 9211901 NAA16 79612 N(alpha)-acetyltransferase 16, NatA auxiliary subunit cytoplasm Cellular component - IGFBP3 3486 insulin-like growth factor binding protein 3 positive regulation of MAPK cascade Biological process - PSMB11 122706 proteasome (prosome, macropain) subunit, beta type, 11 positive regulation of canonical Wnt signaling pathway Biological process - SNX3 8724 sorting nexin 3 retromer complex Cellular component 21725319 XBP1 7494 X-box binding protein 1 sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function - FOXA2 3170 forkhead box A2 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 12642491 SEPP1 6414 selenoprotein P, plasma, 1 extracellular region Cellular component 14718574 RPS6 6194 ribosomal protein S6 cell body Cellular component 15121898 OR10Q1 219960 olfactory receptor, family 10, subfamily Q, member 1 G-protein coupled receptor activity Molecular function - PCNA 5111 proliferating cell nuclear antigen nucleoplasm Cellular component - MAP3K1 4214 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase regulation of mitotic cell cycle Biological process - COG8 84342 component of oligomeric golgi complex 8 membrane Cellular component 19946888 RNASE4 6038 ribonuclease, RNase A family, 4 cellular response to starvation Biological process - TBX19 9095 T-box 19 regulation of cell proliferation Biological process - UBE2G1 7326 ubiquitin-conjugating enzyme E2G 1 protein K48-linked ubiquitination Biological process 20061386 FOLH1B 219595 folate hydrolase 1B metal ion binding Molecular function - ABCA3 21 ATP-binding cassette, sub-family A (ABC1), member 3 transporter activity Molecular function 9027511 ARF6 382 ADP-ribosylation factor 6 thioesterase binding Molecular function 15509780 ACTB 60 actin, beta kinesin binding Molecular function 18680169 OR10C1 442194 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) G-protein coupled receptor signaling pathway Biological process - BNC2 54796 basonuclin 2 regulation of transcription, DNA-templated Biological process - ITGA5 3678 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) integrin binding Molecular function - RTN1 6252 reticulon 1 endoplasmic reticulum membrane Cellular component 17684057 MICALL1 85377 MICAL-like 1 cellular response to nerve growth factor stimulus Biological process - CHD3 1107 chromodomain helicase DNA binding protein 3 cytoplasm Cellular component 17626165 DNMT3A 1788 DNA (cytosine-5-)-methyltransferase 3 alpha C-5 methylation of cytosine Biological process - TCF4 6925 transcription factor 4 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 8978694 PRKG2 5593 protein kinase, cGMP-dependent, type II cGMP-dependent protein kinase activity Molecular function - SCAI 286205 suppressor of cancer cell invasion integral component of membrane Cellular component - SULT1B1 27284 sulfotransferase family, cytosolic, 1B, member 1 small molecule metabolic process Biological process - WT1 7490 Wilms tumor 1 adrenal cortex formation Biological process - NDUFAF3 25915 NADH dehydrogenase (ubiquinone) complex I, assembly factor 3 mitochondrial respiratory chain complex I assembly Biological process 19463981 GRAMD3 65983 GRAM domain containing 3 protein binding Molecular function 25416956 DYNLL1 8655 dynein, light chain, LC8-type 1 COP9 signalosome Cellular component 18850735 OR5T1 390155 olfactory receptor, family 5, subfamily T, member 1 plasma membrane Cellular component - GPC3 2719 glypican 3 peptidyl-dipeptidase inhibitor activity Molecular function 17549790 CYB5A 1528 cytochrome b5 type A (microsomal) mitochondrial outer membrane Cellular component - CDKN1C 1028 cyclin-dependent kinase inhibitor 1C (p57, Kip2) cyclin-dependent protein serine/threonine kinase inhibitor activity Molecular function - ASS1 445 argininosuccinate synthase 1 extracellular exosome Cellular component 19056867 CHD4 1108 chromodomain helicase DNA binding protein 4 RNA polymerase II repressing transcription factor binding Molecular function 22926524 IL17RB 55540 interleukin 17 receptor B cytokine receptor activity Molecular function 10815801 OR52N2 390077 olfactory receptor, family 52, subfamily N, member 2 integral component of membrane Cellular component - CACNG2 10369 calcium channel, voltage-dependent, gamma subunit 2 voltage-gated calcium channel complex Cellular component - ADORA1 134 adenosine A1 receptor response to hypoxia Biological process - TAF7L 54457 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa transcription factor TFIID complex Cellular component - FFAR2 2867 free fatty acid receptor 2 lipid storage Biological process - DIS3L 115752 DIS3 like exosome 3'-5' exoribonuclease centrosome Cellular component - CPSF1 29894 cleavage and polyadenylation specific factor 1, 160kDa mRNA cleavage Biological process 7590244 IQGAP3 128239 IQ motif containing GTPase activating protein 3 activation of MAPK activity Biological process - RBM27 54439 RNA binding motif protein 27 mRNA processing Biological process - KIR2DL2 3803 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 plasma membrane Cellular component - PALM 5064 paralemmin cytoskeleton organization Biological process - BDKRB2 624 bradykinin receptor B2 smooth muscle contraction Biological process 17077303 IL4 3565 interleukin 4 regulation of isotype switching Biological process 11418631 UBE2B 7320 ubiquitin-conjugating enzyme E2B maintenance of chromatin silencing Biological process - VPS26B 112936 vacuolar protein sorting 26 homolog B (S. pombe) retrograde transport, endosome to Golgi Biological process - SUMO3 6612 small ubiquitin-like modifier 3 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Biological process - CLIP3 25999 CAP-GLY domain containing linker protein 3 membrane biogenesis Biological process 11854307 IRS1 3667 insulin receptor substrate 1 positive regulation of cell proliferation Biological process 17925406 SFRP2 6423 secreted frizzled-related protein 2 negative regulation of JUN kinase activity Biological process - NEIL2 252969 nei endonuclease VIII-like 2 (E. coli) nucleoplasm Cellular component - OR8A1 390275 olfactory receptor, family 8, subfamily A, member 1 plasma membrane Cellular component - EREG 2069 epiregulin growth factor activity Molecular function - AGK 55750 acylglycerol kinase intracellular membrane-bounded organelle Cellular component - FOXP1 27086 forkhead box P1 response to lipopolysaccharide Biological process 18799727 EPHX2 2053 epoxide hydrolase 2, cytoplasmic small molecule metabolic process Biological process - RASD2 23551 RASD family, member 2 positive regulation of protein sumoylation Biological process - BST1 683 bone marrow stromal cell antigen 1 extracellular exosome Cellular component 23376485 OR7D2 162998 olfactory receptor, family 7, subfamily D, member 2 plasma membrane Cellular component - FLT3LG 2323 fms-related tyrosine kinase 3 ligand protein homodimerization activity Molecular function - ETS1 2113 v-ets avian erythroblastosis virus E26 oncogene homolog 1 response to interleukin-1 Biological process - VEGFA 7422 vascular endothelial growth factor A dopaminergic neuron differentiation Biological process - NUDT5 11164 nudix (nucleoside diphosphate linked moiety X)-type motif 5 intracellular Cellular component 10567213 PCK2 5106 phosphoenolpyruvate carboxykinase 2 (mitochondrial) phosphoenolpyruvate carboxykinase activity Molecular function 8645161 FGFR1 2260 fibroblast growth factor receptor 1 chordate embryonic development Biological process 15863030 OTUD4 54726 OTU deubiquitinase 4 protein K48-linked deubiquitination Biological process 23827681 PMEL 6490 premelanosome protein endoplasmic reticulum membrane Cellular component 15695812 RILP 83547 Rab interacting lysosomal protein late endosome Cellular component 11179213 EPRS 2058 glutamyl-prolyl-tRNA synthetase GTPase binding Molecular function 24337748 FOXJ1 2302 forkhead box J1 spermatogenesis Biological process 9073514 MATK 4145 megakaryocyte-associated tyrosine kinase protein phosphorylation Biological process 7530249 ZDHHC22 283576 zinc finger, DHHC-type containing 22 protein palmitoylation Biological process - DTNB 1838 dystrobrevin, beta zinc ion binding Molecular function - PCBD1 5092 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha identical protein binding Molecular function 16189514 ACHE 43 acetylcholinesterase (Yt blood group) muscle organ development Biological process 11283752 DARS 1615 aspartyl-tRNA synthetase aminoacylase activity Molecular function 8449960 DUSP2 1844 dual specificity phosphatase 2 MAP kinase tyrosine/serine/threonine phosphatase activity Molecular function - RIC8A 60626 RIC8 guanine nucleotide exchange factor A adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Biological process - ZNF763 284390 zinc finger protein 763 extracellular exosome Cellular component 23376485 SMIM13 221710 small integral membrane protein 13 integral component of membrane Cellular component - ZNF366 167465 zinc finger protein 366 estrogen receptor binding Molecular function 17085477 FBLN5 10516 fibulin 5 extracellular matrix Cellular component 20551380 ADAR 103 adenosine deaminase, RNA-specific nucleolus Cellular component - PTPN22 26191 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) regulation of B cell receptor signaling pathway Biological process 19265110 STOX1 219736 storkhead box 1 regulation of transcription from RNA polymerase II promoter in response to hypoxia Biological process 24738702 MYH14 79784 myosin, heavy chain 14, non-muscle actin-dependent ATPase activity Molecular function 24072716 EXOSC5 56915 exosome component 5 polyadenylation-dependent snoRNA 3'-end processing Biological process - CCR7 1236 chemokine (C-C motif) receptor 7 lymphocyte migration into lymph node Biological process 18379575 CD300LG 146894 CD300 molecule-like family member g immunoglobulin transcytosis in epithelial cells Biological process - ELK3 2004 ELK3, ETS-domain protein (SRF accessory protein 2) signal transduction Biological process 7958835 IFNA16 3449 interferon, alpha 16 type I interferon receptor binding Molecular function 6548765 SI 6476 sucrase-isomaltase (alpha-glucosidase) carbohydrate binding Molecular function - PLET1 349633 placenta expressed transcript 1 cell differentiation Biological process - TPO 7173 thyroid peroxidase response to oxidative stress Biological process - ZNF200 7752 zinc finger protein 200 regulation of transcription, DNA-templated Biological process - DNAJC6 9829 DnaJ (Hsp40) homolog, subfamily C, member 6 regulation of clathrin-mediated endocytosis Biological process - NPC2 10577 Niemann-Pick disease, type C2 glycolipid transport Biological process 17018531 GPER1 2852 G protein-coupled estrogen receptor 1 positive regulation of cAMP biosynthetic process Biological process 15539556 DDX41 51428 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 apoptotic process Biological process 10607561 LATS2 26524 large tumor suppressor kinase 2 cytoplasm Cellular component - SIGLEC1 6614 sialic acid binding Ig-like lectin 1, sialoadhesin positive regulation of T cell apoptotic process Biological process - NOL4L 140688 nucleolar protein 4-like cytoplasm Cellular component - ZP3 7784 zona pellucida glycoprotein 3 (sperm receptor) acrosomal vesicle Cellular component - EPS8L1 54869 EPS8-like 1 Rho guanyl-nucleotide exchange factor activity Molecular function 14565974 SDHC 6391 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa small molecule metabolic process Biological process - LRRK2 120892 leucine-rich repeat kinase 2 response to oxidative stress Biological process 19692353 SSPN 8082 sarcospan muscle contraction Biological process 9395445 CSPG4 1464 chondroitin sulfate proteoglycan 4 protein kinase binding Molecular function 10587647 CYB5R4 51167 cytochrome b5 reductase 4 endoplasmic reticulum Cellular component 15131110 DYRK1A 1859 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A circadian rhythm Biological process - DAD1 1603 defender against cell death 1 negative regulation of apoptotic process Biological process - PRMT5 10419 protein arginine methyltransferase 5 cell proliferation Biological process 9843966 VPS4A 27183 vacuolar protein sorting 4 homolog A (S. cerevisiae) vesicle-mediated transport Biological process 11563910 ERAP1 51752 endoplasmic reticulum aminopeptidase 1 angiogenesis Biological process 15691326 TGFB1 7040 transforming growth factor, beta 1 positive regulation of smooth muscle cell differentiation Biological process - TEK 7010 TEK tyrosine kinase, endothelial positive regulation of angiogenesis Biological process 18425120 UGT1A4 54657 UDP glucuronosyltransferase 1 family, polypeptide A4 flavonoid glucuronidation Biological process - TRIM4 89122 tripartite motif containing 4 protein trimerization Biological process 17156811 RNF20 56254 ring finger protein 20, E3 ubiquitin protein ligase negative regulation of mRNA polyadenylation Biological process 19575011 MS4A3 932 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) regulation of cell cycle Biological process - SUSD6 9766 sushi domain containing 6 protein binding Molecular function 25416956 CATSPER2 117155 cation channel, sperm associated 2 membrane depolarization during action potential Biological process - BRSK2 9024 BR serine/threonine kinase 2 establishment of cell polarity Biological process - OR52N4 390072 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) G-protein coupled receptor activity Molecular function - CAND1 55832 cullin-associated and neddylation-dissociated 1 TBP-class protein binding Molecular function - PSMA8 143471 proteasome (prosome, macropain) subunit, alpha type, 8 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Biological process - NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 inflammatory response Biological process 7739550 MAPK14 1432 mitogen-activated protein kinase 14 stress-activated MAPK cascade Biological process - COL28A1 340267 collagen, type XXVIII, alpha 1 extracellular region Cellular component - OSBPL3 26031 oxysterol binding protein-like 3 membrane Cellular component 19946888 SPHK1 8877 sphingosine kinase 1 cellular response to hydrogen peroxide Biological process - AKR1B15 441282 aldo-keto reductase family 1, member B15 oxidation-reduction process Biological process - OR5J2 282775 olfactory receptor, family 5, subfamily J, member 2 sensory perception of smell Biological process - ZFYVE16 9765 zinc finger, FYVE domain containing 16 metal ion binding Molecular function - RARA 5914 retinoic acid receptor, alpha steroid hormone mediated signaling pathway Biological process - EIF3E 3646 eukaryotic translation initiation factor 3, subunit E nucleoplasm Cellular component 17468741 CENPK 64105 centromere protein K condensed chromosome kinetochore Cellular component - KIF9 64147 kinesin family member 9 regulation of podosome assembly Biological process 21119006 SELP 6403 selectin P (granule membrane protein 140kDa, antigen CD62) integral component of plasma membrane Cellular component 1701178 CDKN2AIP 55602 CDKN2A interacting protein regulation of protein stability Biological process 12154087 ILK 3611 integrin-linked kinase protein complex Cellular component - RSPH6A 81492 radial spoke head 6 homolog A (Chlamydomonas) intracellular Cellular component - TMPRSS2 7113 transmembrane protease, serine 2 proteolysis Biological process 21068237 ASIC2 40 acid sensing (proton gated) ion channel 2 integral component of plasma membrane Cellular component - MTFMT 123263 mitochondrial methionyl-tRNA formyltransferase conversion of methionyl-tRNA to N-formyl-methionyl-tRNA Biological process - ZFPM2 23414 zinc finger protein, FOG family member 2 negative regulation of transcription from RNA polymerase II promoter Biological process - TREM1 54210 triggering receptor expressed on myeloid cells 1 extracellular region Cellular component - GRM2 2912 glutamate receptor, metabotropic 2 G-protein coupled glutamate receptor signaling pathway Biological process - CSF1 1435 colony stimulating factor 1 (macrophage) plasma membrane Cellular component - VAV1 7409 vav 1 guanine nucleotide exchange factor fibroblast growth factor receptor signaling pathway Biological process - MICA 100507436 MHC class I polypeptide-related sequence A gamma-delta T cell activation Biological process 9497295 DPEP1 1800 dipeptidase 1 (renal) cellular response to drug Biological process 20435919 GDF5 8200 growth differentiation factor 5 intracellular Cellular component 21976273 ERN1 2081 endoplasmic reticulum to nucleus signaling 1 RNA phosphodiester bond hydrolysis, endonucleolytic Biological process - C9orf142 286257 chromosome 9 open reading frame 142 protein homodimerization activity Molecular function 25574025 PSMD10 5716 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 positive regulation of protein ubiquitination Biological process 16023600 MEOX2 4223 mesenchyme homeobox 2 multicellular organismal development Biological process 7713505 STX16 8675 syntaxin 16 retrograde transport, endosome to Golgi Biological process 17389686 PLGRKT 55848 plasminogen receptor, C-terminal lysine transmembrane protein positive regulation of plasminogen activation Biological process - TARDBP 23435 TAR DNA binding protein RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - SDC2 6383 syndecan 2 lysosomal lumen Cellular component - CHCHD3 54927 coiled-coil-helix-coiled-coil-helix domain containing 3 protein complex scaffold Molecular function - RXFP3 51289 relaxin/insulin-like family peptide receptor 3 positive regulation of cytokinesis Biological process 22888021 CATSPER3 347732 cation channel, sperm associated 3 sperm motility Biological process - PKN1 5585 protein kinase N1 nucleus Cellular component 12514133 OXA1L 5018 oxidase (cytochrome c) assembly 1-like mitochondrion Cellular component - TPR 7175 translocated promoter region, nuclear basket protein positive regulation of heterochromatin assembly Biological process 20407419 RAMP3 10268 receptor (G protein-coupled) activity modifying protein 3 intracellular protein transport Biological process - CCT2 10576 chaperonin containing TCP1, subunit 2 (beta) chaperonin-containing T-complex Cellular component 23011926 PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 neuromuscular junction development Biological process - ALS2 57679 amyotrophic lateral sclerosis 2 (juvenile) receptor recycling Biological process - PEG3 5178 paternally expressed 3 in utero embryonic development Biological process - ANAPC4 29945 anaphase promoting complex subunit 4 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Biological process - ACP5 54 acid phosphatase 5, tartrate resistant lysosome Cellular component - P2RX6 9127 purinergic receptor P2X, ligand gated ion channel, 6 purinergic nucleotide receptor activity Molecular function 12088286 SLC7A4 6545 solute carrier family 7, member 4 antiporter activity Molecular function - CCT6A 908 chaperonin containing TCP1, subunit 6A (zeta 1) poly(A) RNA binding Molecular function 22658674 CALM3 808 calmodulin 3 (phosphorylase kinase, delta) negative regulation of ryanodine-sensitive calcium-release channel activity Biological process - LAMP2 3920 lysosomal-associated membrane protein 2 platelet degranulation Biological process - GRIA3 2892 glutamate receptor, ionotropic, AMPA 3 plasma membrane Cellular component - AKAP7 9465 A kinase (PRKA) anchor protein 7 ion transport Biological process 9545239 ZNF45 7596 zinc finger protein 45 DNA binding Molecular function - ZNF227 7770 zinc finger protein 227 nucleus Cellular component - CASP8 841 caspase 8, apoptosis-related cysteine peptidase death-inducing signaling complex assembly Biological process - DROSHA 29102 drosha, ribonuclease type III miRNA metabolic process Biological process - WNT8A 7478 wingless-type MMTV integration site family, member 8A proteinaceous extracellular matrix Cellular component - CTGF 1490 connective tissue growth factor epidermis development Biological process 10809757 IFNG 3458 interferon, gamma interferon-gamma receptor binding Molecular function - PSMB7 5695 proteasome (prosome, macropain) subunit, beta type, 7 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Biological process - FLOT1 10211 flotillin 1 positive regulation of myoblast fusion Biological process 24046456 HMGCR 3156 3-hydroxy-3-methylglutaryl-CoA reductase coenzyme binding Molecular function 10698924 GLUL 2752 glutamate-ammonia ligase response to glucose Biological process - SYNCRIP 10492 synaptotagmin binding, cytoplasmic RNA interacting protein negative regulation of translation Biological process 15479637 MYD88 4615 myeloid differentiation primary response 88 neurotrophin TRK receptor signaling pathway Biological process - PPP1CA 5499 protein phosphatase 1, catalytic subunit, alpha isozyme nucleus Cellular component 11739654 CCNA2 890 cyclin A2 regulation of cyclin-dependent protein serine/threonine kinase activity Biological process - NTF3 4908 neurotrophin 3 growth factor activity Molecular function 23027130 MYLPF 29895 myosin light chain, phosphorylatable, fast skeletal muscle muscle contraction Biological process - CYP11A1 1583 cytochrome P450, family 11, subfamily A, polypeptide 1 cellular response to lipopolysaccharide Biological process - PTGES 9536 prostaglandin E synthase arachidonic acid metabolic process Biological process - ATP5L 10632 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) Cellular component - PRKAA1 5562 protein kinase, AMP-activated, alpha 1 catalytic subunit insulin receptor signaling pathway Biological process - TM7SF2 7108 transmembrane 7 superfamily member 2 endoplasmic reticulum membrane Cellular component - SUFU 51684 suppressor of fused homolog (Drosophila) protein kinase binding Molecular function 20643644 FGFR2 2263 fibroblast growth factor receptor 2 lung development Biological process - DCLK1 9201 doublecortin-like kinase 1 neuron migration Biological process - ABCC1 4363 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 arachidonic acid metabolic process Biological process - TP53 7157 tumor protein p53 circadian behavior Biological process - NBN 4683 nibrin positive regulation of protein autophosphorylation Biological process 15790808 TLL1 7092 tolloid-like 1 collagen binding Molecular function - CCT6A 908 chaperonin containing TCP1, subunit 6A (zeta 1) ATP binding Molecular function - FUT2 2524 fucosyltransferase 2 (secretor status included) galactoside 2-alpha-L-fucosyltransferase activity Molecular function 11698403 TANK 10010 TRAF family member-associated NFKB activator metal ion binding Molecular function - APC 324 adenomatous polyposis coli beta-catenin destruction complex Cellular component 16188939 GK5 256356 glycerol kinase 5 (putative) glycerol catabolic process Biological process - MMP9 4318 matrix metallopeptidase 9 protein binding Molecular function 16512877 CDC16 8881 cell division cycle 16 cell division Biological process - CDK5RAP2 55755 CDK5 regulatory subunit associated protein 2 microtubule Cellular component 19553473 PSMA4 5685 proteasome (prosome, macropain) subunit, alpha type, 4 proteasome-mediated ubiquitin-dependent protein catabolic process Biological process - TRAF3 7187 TNF receptor-associated factor 3 regulation of apoptotic process Biological process - MAB21L1 4081 mab-21-like 1 (C. elegans) camera-type eye development Biological process - ZNF814 730051 zinc finger protein 814 intracellular Cellular component - GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A response to drug Biological process - RPL18 6141 ribosomal protein L18 translational termination Biological process - PPP2R5D 5528 protein phosphatase 2, regulatory subunit B', delta cytosol Cellular component - TGM7 116179 transglutaminase 7 protein-glutamine gamma-glutamyltransferase activity Molecular function - VPS37A 137492 vacuolar protein sorting 37 homolog A (S. cerevisiae) viral life cycle Biological process - HABP2 3026 hyaluronan binding protein 2 proteolysis Biological process - AURKA 6790 aurora kinase A chromosome passenger complex Cellular component - HHEX 3087 hematopoietically expressed homeobox multicellular organism growth Biological process - RAB1B 81876 RAB1B, member RAS oncogene family pre-autophagosomal structure membrane Cellular component 20545908 BACE1 23621 beta-site APP-cleaving enzyme 1 protein binding Molecular function 16407538 MECOM 2122 MDS1 and EVI1 complex locus renal system development Biological process - METTL3 56339 methyltransferase like 3 mRNA destabilization Biological process - ADI1 55256 acireductone dioxygenase 1 cytoplasm Cellular component 11602742 SNX9 51429 sorting nexin 9 cytoplasmic membrane-bounded vesicle Cellular component 15703209 MARK3 4140 MAP/microtubule affinity-regulating kinase 3 protein phosphorylation Biological process - RHOA 387 ras homolog family member A GTP binding Molecular function - IDO1 3620 indoleamine 2,3-dioxygenase 1 positive regulation of type 2 immune response Biological process - NRG1 3084 neuregulin 1 cytokine activity Molecular function 10372964 SLC39A7 7922 solute carrier family 39 (zinc transporter), member 7 transmembrane transport Biological process - ZMYND8 23613 zinc finger, MYND-type containing 8 negative regulation of transcription from RNA polymerase II promoter Biological process - AGBL2 79841 ATP/GTP binding protein-like 2 metallocarboxypeptidase activity Molecular function - NEFH 4744 neurofilament, heavy polypeptide protein kinase binding Molecular function 9313898 GNPDA2 132789 glucosamine-6-phosphate deaminase 2 hydrolase activity Molecular function - NINJ1 4814 ninjurin 1 positive regulation of cell-matrix adhesion Biological process - ATP1A2 477 ATPase, Na+/K+ transporting, alpha 2 polypeptide neurotransmitter uptake Biological process - NME1 4830 NME/NM23 nucleoside diphosphate kinase 1 CTP biosynthetic process Biological process - RIMS3 9783 regulating synaptic membrane exocytosis 3 neurotransmitter transport Biological process - ACVR2A 92 activin A receptor, type IIA signal transduction by protein phosphorylation Biological process - CHD1 1105 chromodomain helicase DNA binding protein 1 nucleus Cellular component 22046413 DNAJC19 131118 DnaJ (Hsp40) homolog, subfamily C, member 19 integral component of membrane Cellular component 16055927 NCAPG2 54892 non-SMC condensin II complex, subunit G2 nucleoplasm Cellular component - BTRC 8945 beta-transducin repeat containing E3 ubiquitin protein ligase regulation of proteasomal protein catabolic process Biological process - FLT4 2324 fms-related tyrosine kinase 4 protein phosphatase binding Molecular function 20826270 ACBD5 91452 acyl-CoA binding domain containing 5 nucleus Cellular component - POLR2G 5436 polymerase (RNA) II (DNA directed) polypeptide G nuclear-transcribed mRNA catabolic process, exonucleolytic Biological process - DOC2B 8447 double C2-like domains, beta positive regulation of vesicle fusion Biological process - KL 9365 klotho extracellular space Cellular component 11792841 AGPAT3 56894 1-acylglycerol-3-phosphate O-acyltransferase 3 integral component of membrane Cellular component - KIFC1 3833 kinesin family member C1 spindle Cellular component - ANP32E 81611 acidic (leucine-rich) nuclear phosphoprotein 32 family, member E histone binding Molecular function 24463511 LPAL2 80350 lipoprotein, Lp(a)-like 2, pseudogene protein binding Molecular function 25416956 TGFB1 7040 transforming growth factor, beta 1 hematopoietic progenitor cell differentiation Biological process 15451575 AHI1 54806 Abelson helper integration site 1 centriole Cellular component - PAK2 5062 p21 protein (Cdc42/Rac)-activated kinase 2 Rac GTPase binding Molecular function - CHD8 57680 chromodomain helicase DNA binding protein 8 p53 binding Molecular function - BTG4 54766 B-cell translocation gene 4 negative regulation of cell proliferation Biological process 10995567 PPP1R9B 84687 protein phosphatase 1, regulatory subunit 9B cytoskeleton Cellular component - KDM1A 23028 lysine (K)-specific demethylase 1A regulation of primitive erythrocyte differentiation Biological process - AKT1 207 v-akt murine thymoma viral oncogene homolog 1 cellular response to epidermal growth factor stimulus Biological process - NTN1 9423 netrin 1 positive regulation of cell proliferation Biological process - DNAJA2 10294 DnaJ (Hsp40) homolog, subfamily A, member 2 membrane Cellular component - TOP1MT 116447 topoisomerase (DNA) I, mitochondrial chromatin remodeling Biological process - OPN4 94233 opsin 4 11-cis retinal binding Molecular function 15674244 FYN 2534 FYN proto-oncogene, Src family tyrosine kinase cellular response to platelet-derived growth factor stimulus Biological process - STC2 8614 stanniocalcin 2 endoplasmic reticulum unfolded protein response Biological process - MAPK8IP3 23162 mitogen-activated protein kinase 8 interacting protein 3 protein localization Biological process - RAB3IP 117177 RAB3A interacting protein positive regulation of GTPase activity Biological process - SOS1 6654 son of sevenless homolog 1 (Drosophila) positive regulation of small GTPase mediated signal transduction Biological process - SUN1 23353 Sad1 and UNC84 domain containing 1 intracellular membrane-bounded organelle Cellular component - MYSM1 114803 Myb-like, SWIRM and MPN domains 1 nucleoplasm Cellular component - WNT3A 89780 wingless-type MMTV integration site family, member 3A post-anal tail morphogenesis Biological process - ANKRD45 339416 ankyrin repeat domain 45 protein binding Molecular function 25416956 TLR4 7099 toll-like receptor 4 positive regulation of ERK1 and ERK2 cascade Biological process - HPN 3249 hepsin integral component of membrane Cellular component 19843851 IKBKB 3551 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta stimulatory C-type lectin receptor signaling pathway Biological process - LNX1 84708 ligand of numb-protein X 1, E3 ubiquitin protein ligase ubiquitin-protein transferase activity Molecular function - INO80C 125476 INO80 complex subunit C biological_process Biological process - EIF4EBP2 1979 eukaryotic translation initiation factor 4E binding protein 2 memory Biological process - UQCRFS1 7386 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 response to antibiotic Biological process - CDKN2AIP 55602 CDKN2A interacting protein nucleus Cellular component - NFKBIA 4792 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha cytoplasm Cellular component - CIRBP 1153 cold inducible RNA binding protein response to cold Biological process 9151692 FGFR2 2263 fibroblast growth factor receptor 2 regulation of branching involved in prostate gland morphogenesis Biological process - C3AR1 719 complement component 3a receptor 1 phosphatidylinositol phospholipase C activity Molecular function 8765043 PSMA3 5684 proteasome (prosome, macropain) subunit, alpha type, 3 cellular nitrogen compound metabolic process Biological process - ETS2 2114 v-ets avian erythroblastosis virus E26 oncogene homolog 2 negative regulation of transcription from RNA polymerase II promoter Biological process 12637547 RAP1A 5906 RAP1A, member of RAS oncogene family blood coagulation Biological process - KRTAP8-1 337879 keratin associated protein 8-1 intermediate filament Cellular component - PSENEN 55851 presenilin enhancer gamma secretase subunit Golgi apparatus Cellular component 15274632 IL1A 3552 interleukin 1, alpha negative regulation of cell proliferation Biological process 3493774 PAICS 10606 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase extracellular exosome Cellular component 20458337 GRINA 2907 glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) endoplasmic reticulum calcium ion homeostasis Biological process - TMC2 117532 transmembrane channel-like 2 vestibular reflex Biological process - BICD1 636 bicaudal D homolog 1 (Drosophila) protein localization to organelle Biological process 12447383 MED1 5469 mediator complex subunit 1 cellular response to hepatocyte growth factor stimulus Biological process - CASC5 57082 cancer susceptibility candidate 5 protein binding Molecular function 15231748 GGT5 2687 gamma-glutamyltransferase 5 glutathione biosynthetic process Biological process - TPGS1 91978 tubulin polyglutamylase complex subunit 1 multicellular organismal development Biological process - SRPR 6734 signal recognition particle receptor (docking protein) gene expression Biological process - ALB 213 albumin drug binding Molecular function 10940303 SLC6A8 6535 solute carrier family 6 (neurotransmitter transporter), member 8 integral component of plasma membrane Cellular component - H2AFZ 3015 H2A histone family, member Z nucleosomal DNA binding Molecular function 19633671 CAV3 859 caveolin 3 ion channel binding Molecular function 17060380 C2CD3 26005 C2 calcium-dependent domain containing 3 regulation of proteolysis Biological process - SIAH2 6478 siah E3 ubiquitin protein ligase 2 neuron projection Cellular component - STAT2 6773 signal transducer and activator of transcription 2, 113kDa DNA binding Molecular function - SNRNP200 23020 small nuclear ribonucleoprotein 200kDa (U5) gene expression Biological process - TMOD3 29766 tropomodulin 3 (ubiquitous) erythrocyte development Biological process - AKAP13 11214 A kinase (PRKA) anchor protein 13 nucleus Cellular component - SCN1A 6323 sodium channel, voltage gated, type I alpha subunit voltage-gated sodium channel activity Molecular function 10742094 MMP19 4327 matrix metallopeptidase 19 collagen catabolic process Biological process - USP16 10600 ubiquitin specific peptidase 16 cysteine-type endopeptidase activity Molecular function 17914355 CNNM4 26504 cyclin and CBS domain divalent metal cation transport mediator 4 ion transport Biological process - APEH 327 acylaminoacyl-peptide hydrolase omega peptidase activity Molecular function 17241160 STRAP 11171 serine/threonine kinase receptor associated protein negative regulation of epithelial cell proliferation Biological process 23687415 TEC 7006 tec protein tyrosine kinase extrinsic component of cytoplasmic side of plasma membrane Cellular component - GRIN3A 116443 glutamate receptor, ionotropic, N-methyl-D-aspartate 3A protein phosphatase 2A binding Molecular function - CASK 8573 calcium/calmodulin-dependent serine protein kinase (MAGUK family) basement membrane Cellular component 18664494 SFRP4 6424 secreted frizzled-related protein 4 G-protein coupled receptor activity Molecular function - SCD 6319 stearoyl-CoA desaturase (delta-9-desaturase) endoplasmic reticulum membrane Cellular component - NOMO1 23420 NODAL modulator 1 membrane Cellular component 19946888 SEH1L 81929 SEH1-like (S. cerevisiae) mitotic metaphase plate congression Biological process 17363900 ALOX15 246 arachidonate 15-lipoxygenase positive regulation of ERK1 and ERK2 cascade Biological process 21831839 UNC13B 10497 unc-13 homolog B (C. elegans) signal transduction Biological process 9607201 PDGFC 56034 platelet derived growth factor C growth factor activity Molecular function - HIF1A 3091 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) positive regulation of nitric-oxide synthase activity Biological process 18254728 SYT15 83849 synaptotagmin XV syntaxin binding Molecular function - SLC19A1 6573 solute carrier family 19 (folate transporter), member 1 water-soluble vitamin metabolic process Biological process - ATP5D 513 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit proton-transporting ATPase activity, rotational mechanism Molecular function - NUF2 83540 NUF2, NDC80 kinetochore complex component molecular_function Molecular function - PPP1R3F 89801 protein phosphatase 1, regulatory subunit 3F regulation of glycogen (starch) synthase activity Biological process 21668450 SLC8A1 6546 solute carrier family 8 (sodium/calcium exchanger), member 1 negative regulation of cytosolic calcium ion concentration Biological process - CALM1 801 calmodulin 1 (phosphorylase kinase, delta) small molecule metabolic process Biological process - IGF2 3481 insulin-like growth factor 2 exocrine pancreas development Biological process - ZP2 7783 zona pellucida glycoprotein 2 (sperm receptor) extracellular matrix Cellular component - ATP5G1 516 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) cellular metabolic process Biological process - STX1A 6804 syntaxin 1A (brain) secretory granule Cellular component - ZNF624 57547 zinc finger protein 624 protein binding Molecular function 25416956 SYTL4 94121 synaptotagmin-like 4 syntaxin binding Molecular function - PHF8 23133 PHD finger protein 8 chromatin binding Molecular function 20622854 EDC3 80153 enhancer of mRNA decapping 3 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay Biological process - TP53 7157 tumor protein p53 protein complex assembly Biological process 12915590 NLGN3 54413 neuroligin 3 learning Biological process 12669065 REEP2 51308 receptor accessory protein 2 integral component of plasma membrane Cellular component - ALDH1A3 220 aldehyde dehydrogenase 1 family, member A3 inner ear morphogenesis Biological process - DEFA5 1670 defensin, alpha 5, Paneth cell-specific extracellular region Cellular component - SLC20A2 6575 solute carrier family 20 (phosphate transporter), member 2 plasma membrane Cellular component - OR13A1 79290 olfactory receptor, family 13, subfamily A, member 1 olfactory receptor activity Molecular function - DGUOK 1716 deoxyguanosine kinase ATP binding Molecular function - BMP2KL 347359 BMP2 inducible kinase-like, pseudogene activation of mitophagy in response to mitochondrial depolarization Biological process 22020285 KAT5 10524 K(lysine) acetyltransferase 5 androgen receptor binding Molecular function 15572661 NDUFA11 126328 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa integral component of membrane Cellular component - UMOD 7369 uromodulin apical plasma membrane Cellular component 18025791 SOX8 30812 SRY (sex determining region Y)-box 8 transcription from RNA polymerase II promoter Biological process - RPE 6120 ribulose-5-phosphate-3-epimerase metal ion binding Molecular function 20923965 PINK1 65018 PTEN induced putative kinase 1 peptidyl-serine autophosphorylation Biological process 23626584 KALRN 8997 kalirin, RhoGEF kinase vesicle-mediated transport Biological process 9285789 MRPL24 79590 mitochondrial ribosomal protein L24 mitochondrial translation Biological process - PROC 5624 protein C (inactivator of coagulation factors Va and VIIIa) calcium ion binding Molecular function - CANX 821 calnexin apolipoprotein binding Molecular function - ATP5A1 498 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle protein binding Molecular function 10077593 WNT5A 7474 wingless-type MMTV integration site family, member 5A response to organic substance Biological process 17486081 CHUK 1147 conserved helix-loop-helix ubiquitous kinase striated muscle cell differentiation Biological process - GLB1L 79411 galactosidase, beta 1-like carbohydrate metabolic process Biological process - TNFAIP8L2 79626 tumor necrosis factor, alpha-induced protein 8-like 2 negative regulation of inflammatory response Biological process - ECE2 9718 endothelin converting enzyme 2 cardioblast differentiation Biological process - PRKAR2B 5577 protein kinase, cAMP-dependent, regulatory, type II, beta transmembrane transport Biological process - FNDC3A 22862 fibronectin type III domain containing 3A Sertoli cell development Biological process - TECTA 7007 tectorin alpha cell-matrix adhesion Biological process - RSG1 79363 REM2 and RAB-like small GTPase 1 regulation of vesicle fusion Biological process - NDUFC2 4718 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa respiratory electron transport chain Biological process - CDK16 5127 cyclin-dependent kinase 16 neuron projection development Biological process - ANGPT1 284 angiopoietin 1 sprouting angiogenesis Biological process 10218485 SPON1 10418 spondin 1, extracellular matrix protein cell adhesion Biological process - CNTN1 1272 contactin 1 axon guidance Biological process - SLC1A6 6511 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 L-aspartate transmembrane transport Biological process 7791878 GAK 2580 cyclin G associated kinase intracellular membrane-bounded organelle Cellular component - TGFBR2 7048 transforming growth factor, beta receptor II (70/80kDa) embryonic cranial skeleton morphogenesis Biological process - SLC25A37 51312 solute carrier family 25 (mitochondrial iron transporter), member 37 iron ion transmembrane transport Biological process - BSND 7809 barttin CLCNK-type chloride channel accessory beta subunit chloride channel activity Molecular function - SYTL4 94121 synaptotagmin-like 4 neurexin family protein binding Molecular function - PJA2 9867 praja ring finger 2, E3 ubiquitin protein ligase zinc ion binding Molecular function - GLO1 2739 glyoxalase I methylglyoxal metabolic process Biological process - HNF1B 6928 HNF1 homeobox B ureteric bud elongation Biological process - ECT2 1894 epithelial cell transforming 2 protein homodimerization activity Molecular function 15545273 MBD2 8932 methyl-CpG binding domain protein 2 protein binding Molecular function 12183469 NDRG1 10397 N-myc downstream regulated 1 recycling endosome membrane Cellular component 17786215 ZNF354A 6940 zinc finger protein 354A nucleus Cellular component 21630459 XRCC4 7518 X-ray repair complementing defective repair in Chinese hamster cells 4 isotype switching Biological process - DIXDC1 85458 DIX domain containing 1 canonical Wnt signaling pathway Biological process - SCNN1B 6338 sodium channel, non voltage gated 1 beta subunit integral component of plasma membrane Cellular component 24124190 SH3RF2 153769 SH3 domain containing ring finger 2 phosphatase binding Molecular function 19389623 RALGPS1 9649 Ral GEF with PH domain and SH3 binding motif 1 regulation of Ral protein signal transduction Biological process 10747847 NCBP1 4686 nuclear cap binding protein subunit 1, 80kDa positive regulation of mRNA 3'-end processing Biological process 9342333 WDR44 54521 WD repeat domain 44 cytosol Cellular component - MCM10 55388 minichromosome maintenance complex component 10 nucleus Cellular component - ADAM17 6868 ADAM metallopeptidase domain 17 T cell differentiation in thymus Biological process 10433800 BCL2 596 B-cell CLL/lymphoma 2 metanephros development Biological process - PSMA2 5683 proteasome (prosome, macropain) subunit, alpha type, 2 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest Biological process - UBE2B 7320 ubiquitin-conjugating enzyme E2B cellular response to insulin stimulus Biological process - MMP14 4323 matrix metallopeptidase 14 (membrane-inserted) branching morphogenesis of an epithelial tube Biological process - CHRNA5 1138 cholinergic receptor, nicotinic, alpha 5 (neuronal) ligand-gated ion channel activity Molecular function 20438829 OR51B5 282763 olfactory receptor, family 51, subfamily B, member 5 G-protein coupled receptor signaling pathway Biological process - ZNF318 24149 zinc finger protein 318 meiotic cell cycle Biological process - TRIM28 10155 tripartite motif containing 28 embryonic placenta morphogenesis Biological process - BBS2 583 Bardet-Biedl syndrome 2 membrane Cellular component - PHOSPHO2 493911 phosphatase, orphan 2 pyridoxal phosphatase activity Molecular function - CLRN1 7401 clarin 1 lamellipodium Cellular component 19423712 TLR2 7097 toll-like receptor 2 negative regulation of cell proliferation Biological process - IL6ST 3572 interleukin 6 signal transducer interleukin-6 receptor binding Molecular function 12829785 FZD2 2535 frizzled class receptor 2 Wnt-activated receptor activity Molecular function - WNT8B 7479 wingless-type MMTV integration site family, member 8B cell fate commitment Biological process - FBXL21 26223 F-box and leucine-rich repeat protein 21 (gene/pseudogene) SCF ubiquitin ligase complex Cellular component - RAD51AP1 10635 RAD51 associated protein 1 single-stranded DNA binding Molecular function 9396801 HRNR 388697 hornerin extracellular exosome Cellular component 21362503 NR2F2 7026 nuclear receptor subfamily 2, group F, member 2 negative regulation of cyclin-dependent protein serine/threonine kinase activity Biological process 19210544 FOXC2 2303 forkhead box C2 sequence-specific DNA binding transcription factor activity Molecular function 9169153 GABARAPL3 23766 GABA(A) receptors associated protein like 3, pseudogene autophagosome assembly Biological process - PICK1 9463 protein interacting with PRKCA 1 postsynaptic membrane Cellular component - RNF146 81847 ring finger protein 146 cytosol Cellular component - MCM2 4171 minichromosome maintenance complex component 2 metal ion binding Molecular function - ITGA3 3675 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) fibronectin binding Molecular function - INTS3 65123 integrator complex subunit 3 protein binding Molecular function 16239144 IL6R 3570 interleukin 6 receptor ciliary neurotrophic factor receptor activity Molecular function 12643274 MRC2 9902 mannose receptor, C type 2 protein binding Molecular function 7904248 TEF 7008 thyrotrophic embryonic factor transcription, DNA-templated Biological process - SMG7 9887 SMG7 nonsense mediated mRNA decay factor nucleus Cellular component 14636577 PCDHB12 56124 protocadherin beta 12 cell adhesion Biological process 10380929 CHCHD6 84303 coiled-coil-helix-coiled-coil-helix domain containing 6 mitochondrion Cellular component 22228767 PTPRT 11122 protein tyrosine phosphatase, receptor type, T protein tyrosine phosphatase activity Molecular function 16973135 PLK5 126520 polo-like kinase 5 positive regulation of neuron projection development Biological process 21245385 CHMP6 79643 charged multivesicular body protein 6 cytosol Cellular component - RAD51D 5892 RAD51 paralog D single-stranded DNA binding Molecular function 10871607 COL16A1 1307 collagen, type XVI, alpha 1 integrin activation Biological process 16754661 HBA2 3040 hemoglobin, alpha 2 blood microparticle Cellular component 22516433 EARS2 124454 glutamyl-tRNA synthetase 2, mitochondrial tRNA aminoacylation for protein translation Biological process - GATA4 2626 GATA binding protein 4 nuclear chromatin Cellular component - ANXA2P2 304 annexin A2 pseudogene 2 melanosome Cellular component - WTAP 9589 Wilms tumor 1 associated protein RNA splicing Biological process - FNIP1 96459 folliculin interacting protein 1 protein binding Molecular function 17028174 CDH13 1012 cadherin 13 cell junction assembly Biological process - Sep-02 4735 septin 2 nucleus Cellular component - FAM220A 84792 family with sequence similarity 220, member A nucleus Cellular component - BCL2L13 23786 BCL2-like 13 (apoptosis facilitator) activation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 11262395 NOTCH2 4853 notch 2 positive regulation of Ras protein signal transduction Biological process 11306509 TGFB1I1 7041 transforming growth factor beta 1 induced transcript 1 extracellular matrix Cellular component 20551380 LGI3 203190 leucine-rich repeat LGI family, member 3 cell junction Cellular component - HIF1A 3091 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) protein binding Molecular function 11292862 IRGM 345611 immunity-related GTPase family, M hydrolase activity Molecular function - ACADVL 37 acyl-CoA dehydrogenase, very long chain endoplasmic reticulum unfolded protein response Biological process - LYN 4067 LYN proto-oncogene, Src family tyrosine kinase negative regulation of B cell proliferation Biological process - RAB8A 4218 RAB8A, member RAS oncogene family protein kinase binding Molecular function - CSNK1G2 1455 casein kinase 1, gamma 2 endocytosis Biological process - NEK4 6787 NIMA-related kinase 4 manganese ion binding Molecular function - PPP1R3G 648791 protein phosphatase 1, regulatory subunit 3G cytoplasm Cellular component - BAX 581 BCL2-associated X protein regulation of protein heterodimerization activity Biological process 9111042 DUSP16 80824 dual specificity phosphatase 16 nucleoplasm Cellular component - SOD2 6648 superoxide dismutase 2, mitochondrial intrinsic apoptotic signaling pathway in response to oxidative stress Biological process - SLC1A6 6511 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 Golgi apparatus Cellular component - WBSCR17 64409 Williams-Beuren syndrome chromosome region 17 metal ion binding Molecular function - CYP17A1 1586 cytochrome P450, family 17, subfamily A, polypeptide 1 ovulation Biological process - RBM3 5935 RNA binding motif (RNP1, RRM) protein 3 regulation of translation Biological process - RUNX1 861 runt-related transcription factor 1 regulatory region DNA binding Molecular function 21873977 AGPAT4 56895 1-acylglycerol-3-phosphate O-acyltransferase 4 CDP-diacylglycerol biosynthetic process Biological process - HELZ 9931 helicase with zinc finger metal ion binding Molecular function - OR52A4P 390053 olfactory receptor, family 52, subfamily A, member 4, pseudogene integral component of membrane Cellular component - SGCZ 137868 sarcoglycan, zeta muscle cell cellular homeostasis Biological process 17438352 SLC20A1 6574 solute carrier family 20 (phosphate transporter), member 1 integral component of plasma membrane Cellular component 8041748 RASGRP1 10125 RAS guanyl releasing protein 1 (calcium and DAG-regulated) positive regulation of interferon-gamma secretion Biological process 19933860 DDT 1652 D-dopachrome tautomerase melanin biosynthetic process Biological process - SPICE1 152185 spindle and centriole associated protein 1 cell division Biological process - PEX3 8504 peroxisomal biogenesis factor 3 lipid binding Molecular function 19715730 BMP4 652 bone morphogenetic protein 4 endocardial cushion development Biological process 18076106 VASP 7408 vasodilator-stimulated phosphoprotein actin polymerization or depolymerization Biological process - CCDC62 84660 coiled-coil domain containing 62 ligand-dependent nuclear receptor transcription coactivator activity Molecular function 19126643 PRPF19 27339 pre-mRNA processing factor 19 cellular protein localization Biological process 18263876 RPL36 25873 ribosomal protein L36 membrane Cellular component 19946888 FOXP2 93986 forkhead box P2 putamen development Biological process 11872605 SHC4 399694 SHC (Src homology 2 domain containing) family, member 4 stem cell differentiation Biological process - MYOD1 4654 myogenic differentiation 1 transcription factor binding Molecular function - OR7C1 26664 olfactory receptor, family 7, subfamily C, member 1 G-protein coupled receptor signaling pathway Biological process - BTK 695 Bruton agammaglobulinemia tyrosine kinase B cell activation Biological process 19290921 CHRM2 1129 cholinergic receptor, muscarinic 2 sensory perception of chemical stimulus Biological process - CCDC30 728621 coiled-coil domain containing 30 extracellular exosome Cellular component 23376485 MSX1 4487 msh homeobox 1 pituitary gland development Biological process - SH2B1 25970 SH2B adaptor protein 1 membrane Cellular component - BIN2 51411 bridging integrator 2 podosome assembly Biological process 23285027 COL5A2 1290 collagen, type V, alpha 2 endoplasmic reticulum lumen Cellular component - PTPRU 10076 protein tyrosine phosphatase, receptor type, U organ regeneration Biological process - CPEB1 64506 cytoplasmic polyadenylation element binding protein 1 synaptonemal complex assembly Biological process - DLG1 1739 discs, large homolog 1 (Drosophila) hard palate development Biological process - PSME1 5720 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) small molecule metabolic process Biological process - RIPK3 11035 receptor-interacting serine-threonine kinase 3 innate immune response Biological process - PSMB10 5699 proteasome (prosome, macropain) subunit, beta type, 10 regulation of cellular amino acid metabolic process Biological process - PROM1 8842 prominin 1 photoreceptor outer segment Cellular component - OLFM4 10562 olfactomedin 4 extracellular space Cellular component 16566923 PTPRK 5796 protein tyrosine phosphatase, receptor type, K beta-catenin binding Molecular function 8663237 AURKAIP1 54998 aurora kinase A interacting protein 1 mitochondrial translation Biological process - PTCH1 5727 patched 1 protein processing Biological process - NFKB2 4791 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) nucleoplasm Cellular component - SEC61A2 55176 Sec61 alpha 2 subunit (S. cerevisiae) antigen processing and presentation of exogenous peptide antigen via MHC class I Biological process - NRROS 375387 negative regulator of reactive oxygen species inflammatory response Biological process - EFCAB10 100130771 EF-hand calcium binding domain 10 calcium ion binding Molecular function - ALOX12 239 arachidonate 12-lipoxygenase lipoxin A4 biosynthetic process Biological process 8250832 HNRNPDL 9987 heterogeneous nuclear ribonucleoprotein D-like poly(A) RNA binding Molecular function 22658674 GABRG1 2565 gamma-aminobutyric acid (GABA) A receptor, gamma 1 cell junction Cellular component - CNR1 1268 cannabinoid receptor 1 (brain) negative regulation of blood pressure Biological process - WNT11 7481 wingless-type MMTV integration site family, member 11 neuroendocrine cell differentiation Biological process 20219091 ANG 283 angiogenin, ribonuclease, RNase A family, 5 endonuclease activity Molecular function 10103013 MPP2 4355 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) signal transduction Biological process 7590743 TNFSF11 8600 tumor necrosis factor (ligand) superfamily, member 11 positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process - ERLIN2 11160 ER lipid raft associated 2 endoplasmic reticulum Cellular component - PRAMEF6 440561 PRAME family member 6 negative regulation of cell differentiation Biological process - IL1RL1 9173 interleukin 1 receptor-like 1 intracellular signal transduction Biological process 1482686 ISL1 3670 ISL LIM homeobox 1 pharyngeal system development Biological process - XBP1 7494 X-box binding protein 1 endothelial cell proliferation Biological process 23529610 EXOC4 60412 exocyst complex component 4 vesicle docking involved in exocytosis Biological process - Mar-09 92979 membrane-associated ring finger (C3HC4) 9 trans-Golgi network Cellular component 14722266 NRG1 3084 neuregulin 1 positive regulation of protein targeting to mitochondrion Biological process 24270810 SLC22A18 5002 solute carrier family 22, member 18 nuclear envelope Cellular component 16314844 FLNA 2316 filamin A, alpha actin crosslink formation Biological process 10051605 PDGFA 5154 platelet-derived growth factor alpha polypeptide response to hypoxia Biological process - ATXN3 4287 ataxin 3 actin cytoskeleton organization Biological process 20637808 MYO7A 4647 myosin VIIA sensory perception of light stimulus Biological process 11398101 INSR 3643 insulin receptor insulin-activated receptor activity Molecular function 6849137 CD2 914 CD2 molecule receptor activity Molecular function 7544493 LRRC8B 23507 leucine rich repeat containing 8 family, member B integral component of membrane Cellular component - SCIN 85477 scinderin extracellular exosome Cellular component 19056867 CTNND1 1500 catenin (cadherin-associated protein), delta 1 vascular endothelial growth factor receptor signaling pathway Biological process - TNR 7143 tenascin R axon guidance Biological process 8940128 HOXB8 3218 homeobox B8 dorsal spinal cord development Biological process - PTPMT1 114971 protein tyrosine phosphatase, mitochondrial 1 nucleus Cellular component 21630459 ENTPD2 954 ectonucleoside triphosphate diphosphohydrolase 2 nucleoside-diphosphatase activity Molecular function - TFDP1 7027 transcription factor Dp-1 positive regulation of transcription from RNA polymerase II promoter Biological process - ACE 1636 angiotensin I converting enzyme tripeptidyl-peptidase activity Molecular function 2983326 SLC13A4 26266 solute carrier family 13 (sodium/sulfate symporter), member 4 plasma membrane Cellular component - MYH10 4628 myosin, heavy chain 10, non-muscle growth cone Cellular component - NCOR2 9612 nuclear receptor corepressor 2 histone deacetylase binding Molecular function 11804585 CAPS 828 calcyphosine activation of mitophagy in response to mitochondrial depolarization Biological process 22020285 TNC 3371 tenascin C positive regulation of cell proliferation Biological process - SLTM 79811 SAFB-like, transcription modulator transcription, DNA-templated Biological process - ANXA9 8416 annexin A9 calcium ion binding Molecular function - HOXA1 3198 homeobox A1 optokinetic behavior Biological process 16155570 ANXA7 310 annexin A7 cell proliferation Biological process - FGD6 55785 FYVE, RhoGEF and PH domain containing 6 small GTPase binding Molecular function - APEX2 27301 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 DNA recombination Biological process - GPR63 81491 G protein-coupled receptor 63 biological_process Biological process - NKX3-1 4824 NK3 homeobox 1 estrogen receptor binding Molecular function 18794125 UBC 7316 ubiquitin C neurotrophin TRK receptor signaling pathway Biological process - NUDT1 4521 nudix (nucleoside diphosphate linked moiety X)-type motif 1 metal ion binding Molecular function - CD70 970 CD70 molecule extracellular exosome Cellular component 20458337 RAPH1 65059 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 lamellipodium Cellular component - MKL1 57591 megakaryoblastic leukemia (translocation) 1 cytosol Cellular component - ADSS 159 adenylosuccinate synthase cellular response to electrical stimulus Biological process - TRAM1 23471 translocation associated membrane protein 1 translation Biological process - KRT27 342574 keratin 27, type I hair follicle morphogenesis Biological process - SOX14 8403 SRY (sex determining region Y)-box 14 negative regulation of transcription from RNA polymerase II promoter Biological process - CST3 1471 cystatin C defense response Biological process 6203523 FGF1 2246 fibroblast growth factor 1 (acidic) positive regulation of cell proliferation Biological process 18187602 HIST1H3J 8356 histone cluster 1, H3j chromatin organization Biological process - PLEKHA1 59338 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 negative regulation of protein kinase B signaling Biological process 14516276 AGTR2 186 angiotensin II receptor, type 2 positive regulation of extrinsic apoptotic signaling pathway Biological process 10406457 WWOX 51741 WW domain containing oxidoreductase coenzyme binding Molecular function 10786676 MAP2K7 5609 mitogen-activated protein kinase kinase 7 toll-like receptor TLR1:TLR2 signaling pathway Biological process - GJA5 2702 gap junction protein, alpha 5, 40kDa atrial ventricular junction remodeling Biological process - RAD17 5884 RAD17 homolog (S. pombe) chromosome, telomeric region Cellular component 15149599 CYTH1 9267 cytohesin 1 lipid binding Molecular function - CALCB 797 calcitonin-related polypeptide beta neuropeptide hormone activity Molecular function 2985435 AGTR1 185 angiotensin II receptor, type 1 regulation of renal sodium excretion Biological process 17159080 KIAA0430 9665 KIAA0430 RNA binding Molecular function - IL10 3586 interleukin 10 leukocyte chemotaxis Biological process 9405662 LIN7A 8825 lin-7 homolog A (C. elegans) plasma membrane Cellular component - TNF 7124 tumor necrosis factor positive regulation of protein transport Biological process 15310755 BBS9 27241 Bardet-Biedl syndrome 9 fat cell differentiation Biological process - CPOX 1371 coproporphyrinogen oxidase mitochondrion Cellular component - FKBP1A 2280 FK506 binding protein 1A, 12kDa cytosol Cellular component - ZP3 7784 zona pellucida glycoprotein 3 (sperm receptor) positive regulation of antral ovarian follicle growth Biological process - AMOT 154796 angiomotin COP9 signalosome Cellular component 18850735 ZFAND5 7763 zinc finger, AN1-type domain 5 face development Biological process - TSC1 7248 tuberous sclerosis 1 response to insulin Biological process 16996505 NCOA1 8648 nuclear receptor coactivator 1 histone acetyltransferase activity Molecular function - TSPY2 64591 testis specific protein, Y-linked 2 cytoplasm Cellular component - XG 7499 Xg blood group molecular_function Molecular function - PIK3CA 5290 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha phosphatidylinositol 3-kinase complex, class IA Cellular component 22402981 CASK 8573 calcium/calmodulin-dependent serine protein kinase (MAGUK family) cytoplasm Cellular component 18664494 CCDC13 152206 coiled-coil domain containing 13 cell projection organization Biological process - SETD6 79918 SET domain containing 6 nucleoplasm Cellular component - RBFA 79863 ribosome binding factor A (putative) rRNA processing Biological process - NRIP1 8204 nuclear receptor interacting protein 1 transcription corepressor activity Molecular function 10364267 PNPLA3 80339 patatin-like phospholipase domain containing 3 phospholipid metabolic process Biological process - ARID3B 10620 AT rich interactive domain 3B (BRIGHT-like) RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - CRHR1 1394 corticotropin releasing hormone receptor 1 behavioral response to cocaine Biological process - MAK 4117 male germ cell-associated kinase regulation of cell cycle Biological process - AXL 558 AXL receptor tyrosine kinase viral entry into host cell Biological process 21047970 ZNF274 10782 zinc finger protein 274 sequence-specific DNA binding transcription factor activity Molecular function 10777669 TNF 7124 tumor necrosis factor necroptotic signaling pathway Biological process 11101870 CLASP1 23332 cytoplasmic linker associated protein 1 cytoplasmic microtubule Cellular component 11290329 OR4N5 390437 olfactory receptor, family 4, subfamily N, member 5 G-protein coupled receptor activity Molecular function - DDX19A 55308 DEAD (Asp-Glu-Ala-Asp) box polypeptide 19A biological_process Biological process - LATS1 9113 large tumor suppressor kinase 1 magnesium ion binding Molecular function 10518011 ADGRL1 22859 adhesion G protein-coupled receptor L1 cell adhesion molecule binding Molecular function - NDUFS7 374291 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) NADH dehydrogenase (ubiquinone) activity Molecular function 9878551 ACTN1 87 actinin, alpha 1 actin filament bundle assembly Biological process - ATP11C 286410 ATPase, class VI, type 11C protein binding Molecular function 21914794 CNDP2 55748 CNDP dipeptidase 2 (metallopeptidase M20 family) metallopeptidase activity Molecular function - ZNF681 148213 zinc finger protein 681 regulation of transcription, DNA-templated Biological process - PARP4 143 poly (ADP-ribose) polymerase family, member 4 DNA binding Molecular function 10100603 NTF3 4908 neurotrophin 3 smooth muscle cell differentiation Biological process - GNAZ 2781 guanine nucleotide binding protein (G protein), alpha z polypeptide GTP binding Molecular function - DOCK2 1794 dedicator of cytokinesis 2 alpha-beta T cell proliferation Biological process - RPGR 6103 retinitis pigmentosa GTPase regulator intraciliary transport Biological process - COPS4 51138 COP9 signalosome subunit 4 protein deneddylation Biological process 21102408 RAF1 5894 Raf-1 proto-oncogene, serine/threonine kinase protein binding Molecular function 10433554 MME 4311 membrane metallo-endopeptidase axon Cellular component - IGHA1 3493 immunoglobulin heavy constant alpha 1 extracellular region Cellular component - TEC 7006 tec protein tyrosine kinase protein binding Molecular function 10518561 SNX29 92017 sorting nexin 29 extracellular exosome Cellular component 23376485 REEP3 221035 receptor accessory protein 3 mitotic nuclear division Biological process - OR6B1 135946 olfactory receptor, family 6, subfamily B, member 1 sensory perception of smell Biological process - TH 7054 tyrosine hydroxylase enzyme binding Molecular function 19703902 HSPA12A 259217 heat shock 70kDa protein 12A biological_process Biological process - ORC5 5001 origin recognition complex, subunit 5 DNA replication initiation Biological process 9765232 GATAD2B 57459 GATA zinc finger domain containing 2B nuclear speck Cellular component - GSK3B 2932 glycogen synthase kinase 3 beta integrin binding Molecular function - CDC27 996 cell division cycle 27 metaphase/anaphase transition of mitotic cell cycle Biological process 7736578 TCF7 6932 transcription factor 7 (T-cell specific, HMG-box) embryonic genitalia morphogenesis Biological process - KIFAP3 22920 kinesin-associated protein 3 Golgi apparatus Cellular component - NOS1 4842 nitric oxide synthase 1 (neuronal) sarcolemma Cellular component 7545544 OR2T27 403239 olfactory receptor, family 2, subfamily T, member 27 G-protein coupled receptor activity Molecular function - OR52N2 390077 olfactory receptor, family 52, subfamily N, member 2 G-protein coupled receptor activity Molecular function - NME2 4831 NME/NM23 nucleoside diphosphate kinase 2 focal adhesion Cellular component 11919189 MRPL46 26589 mitochondrial ribosomal protein L46 biological_process Biological process - HEXIM2 124790 hexamethylene bis-acetamide inducible 2 snRNA binding Molecular function 15713662 ZP3 7784 zona pellucida glycoprotein 3 (sperm receptor) positive regulation of interleukin-4 production Biological process - GJB1 2705 gap junction protein, beta 1, 32kDa cell-cell signaling Biological process 8266101 HMGB4 127540 high mobility group box 4 DNA binding Molecular function - TDRD12 91646 tudor domain containing 12 regulation of gene expression Biological process - LMO3 55885 LIM domain only 3 (rhombotin-like 2) negative regulation of ERK1 and ERK2 cascade Biological process 23823477 SP100 6672 SP100 nuclear antigen response to interferon-gamma Biological process 8810287 FGR 2268 FGR proto-oncogene, Src family tyrosine kinase regulation of cell shape Biological process - RPL37 6167 ribosomal protein L37 RNA binding Molecular function 7545944 HLA-B 3106 major histocompatibility complex, class I, B peptide antigen binding Molecular function - CFLAR 8837 CASP8 and FADD-like apoptosis regulator skeletal muscle tissue regeneration Biological process - CDK5R1 8851 cyclin-dependent kinase 5, regulatory subunit 1 (p35) ephrin receptor binding Molecular function - CHTOP 26097 chromatin target of PRMT1 transcription export complex Cellular component 23299939 IGFBP7 3490 insulin-like growth factor binding protein 7 inner ear development Biological process - WWTR1 25937 WW domain containing transcription regulator 1 protein binding Molecular function 16099986 KCNQ1 3784 potassium channel, voltage gated KQT-like subfamily Q, member 1 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization Molecular function 8528244 GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A response to wounding Biological process - HRAS 3265 Harvey rat sarcoma viral oncogene homolog positive regulation of DNA replication Biological process 9765203 TXNRD3 114112 thioredoxin reductase 3 multicellular organismal development Biological process - IFNG 3458 interferon, gamma CD8-positive, alpha-beta T cell differentiation involved in immune response Biological process - PLAUR 5329 plasminogen activator, urokinase receptor endoplasmic reticulum lumen Cellular component - TAS2R42 353164 taste receptor, type 2, member 42 bitter taste receptor activity Molecular function 20022913 LITAF 9516 lipopolysaccharide-induced TNF factor negative regulation of NF-kappaB import into nucleus Biological process - MAP4K3 8491 mitogen-activated protein kinase kinase kinase kinase 3 response to UV Biological process 9275185 TGFB3 7043 transforming growth factor, beta 3 salivary gland morphogenesis Biological process 18080134 TRAF5 7188 TNF receptor-associated factor 5 positive regulation of cell proliferation Biological process - SSC5D 284297 scavenger receptor cysteine rich family, 5 domains negative regulation of interleukin-8 secretion Biological process - PSMA2 5683 proteasome (prosome, macropain) subunit, alpha type, 2 response to virus Biological process 16548883 ASF1B 55723 anti-silencing function 1B histone chaperone multicellular organismal development Biological process - TMEM63C 57156 transmembrane protein 63C cation transmembrane transport Biological process 24503647 ERVK-6 64006 endogenous retrovirus group K, member 6 integral component of membrane Cellular component - NEK4 6787 NIMA-related kinase 4 signal transduction by protein phosphorylation Biological process - SLC26A4 5172 solute carrier family 26 (anion exchanger), member 4 chloride transmembrane transport Biological process - PKNOX1 5316 PBX/knotted 1 homeobox 1 protein heterodimerization activity Molecular function - STAU1 6780 staufen double-stranded RNA binding protein 1 intracellular mRNA localization Biological process - DSEL 92126 dermatan sulfate epimerase-like Golgi membrane Cellular component - CCL4 6351 chemokine (C-C motif) ligand 4 extracellular region Cellular component - SLC19A1 6573 solute carrier family 19 (folate transporter), member 1 membrane Cellular component 8276792 CREB3L4 148327 cAMP responsive element binding protein 3-like 4 Golgi membrane Cellular component - THPO 7066 thrombopoietin myeloid cell differentiation Biological process - TMIE 259236 transmembrane inner ear inner ear morphogenesis Biological process - METAP1D 254042 methionyl aminopeptidase type 1D (mitochondrial) N-terminal protein amino acid modification Biological process 14532271 MTM1 4534 myotubularin 1 filopodium Cellular component 12118066 AGO2 27161 argonaute RISC catalytic component 2 core promoter binding Molecular function 25336585 AVPR1B 553 arginine vasopressin receptor 1B endosome Cellular component 10858434 ERI1 90459 exoribonuclease 1 DNA catabolic process, exonucleolytic Biological process - APOB 338 apolipoprotein B very-low-density lipoprotein particle Cellular component 15308631 SMAD3 4088 SMAD family member 3 regulation of transforming growth factor beta receptor signaling pathway Biological process 8774881 DYNC1LI1 51143 dynein, cytoplasmic 1, light intermediate chain 1 centrosome Cellular component - THRA 7067 thyroid hormone receptor, alpha protein binding Molecular function 10866662 GRN 2896 granulin intracellular membrane-bounded organelle Cellular component - CD300A 11314 CD300a molecule negative regulation of mast cell degranulation Biological process 16339535 IFT46 56912 intraflagellar transport 46 intraciliary transport Biological process - GAL3ST1 9514 galactose-3-O-sulfotransferase 1 Golgi membrane Cellular component - GSK3B 2932 glycogen synthase kinase 3 beta positive regulation of canonical Wnt signaling pathway Biological process - CTTN 2017 cortactin lamellipodium organization Biological process - RPS17 6218 ribosomal protein S17 viral life cycle Biological process - DAB2IP 153090 DAB2 interacting protein regulation of growth Biological process - NDUFA9 4704 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa mitochondrial inner membrane Cellular component - ANO8 57719 anoctamin 8 integral component of membrane Cellular component - IL12A 3592 interleukin 12A negative regulation of interleukin-17 production Biological process 16482511 MYH10 4628 myosin, heavy chain 10, non-muscle cardiac myofibril assembly Biological process - TMEM237 65062 transmembrane protein 237 regulation of Wnt signaling pathway Biological process 22152675 AP1S3 130340 adaptor-related protein complex 1, sigma 3 subunit protein transporter activity Molecular function - CD36 948 CD36 molecule (thrombospondin receptor) defense response to Gram-positive bacterium Biological process - PDGFB 5155 platelet-derived growth factor beta polypeptide fibroblast growth factor receptor signaling pathway Biological process - MAPK1 5594 mitogen-activated protein kinase 1 T cell receptor signaling pathway Biological process - ALG9 79796 ALG9, alpha-1,2-mannosyltransferase dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity Molecular function - NARFL 64428 nuclear prelamin A recognition factor-like small molecule metabolic process Biological process - NUP62 23636 nucleoporin 62kDa transcription, DNA-templated Biological process - HSP90B2P 7190 heat shock protein 90kDa beta (Grp94), member 2, pseudogene response to stress Biological process - CSNK2B 1460 casein kinase 2, beta polypeptide mitotic cell cycle Biological process - RAB11FIP1 80223 RAB11 family interacting protein 1 (class I) negative regulation of adiponectin secretion Biological process 24040321 OR4E2 26686 olfactory receptor, family 4, subfamily E, member 2 transmembrane signaling receptor activity Molecular function - DIP2C 22982 DIP2 disco-interacting protein 2 homolog C (Drosophila) transcription factor binding Molecular function - RPL9 6133 ribosomal protein L9 cytoplasm Cellular component - MAFF 23764 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F nucleoplasm Cellular component - MAFG 4097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G regulation of cell proliferation Biological process - TAF1L 138474 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like histone acetylation Biological process 12217962 ACTC1 70 actin, alpha, cardiac muscle 1 lamellipodium Cellular component - NOTCH1 4851 notch 1 endocardial cushion morphogenesis Biological process - RPL7A 6130 ribosomal protein L7a SRP-dependent cotranslational protein targeting to membrane Biological process - JUNB 3726 jun B proto-oncogene DNA binding Molecular function 10764760 HOXD13 3239 homeobox D13 regulation of branching involved in prostate gland morphogenesis Biological process - ARHGEF10L 55160 Rho guanine nucleotide exchange factor (GEF) 10-like Rho guanyl-nucleotide exchange factor activity Molecular function - PLK1 5347 polo-like kinase 1 microtubule bundle formation Biological process 12939256 IL1RN 3557 interleukin 1 receptor antagonist cytokine-mediated signaling pathway Biological process - ATRX 546 alpha thalassemia/mental retardation syndrome X-linked DNA binding Molecular function - GLB1L 79411 galactosidase, beta 1-like beta-galactosidase activity Molecular function - NCOA1 8648 nuclear receptor coactivator 1 nucleus Cellular component - PCDHB10 56126 protocadherin beta 10 plasma membrane Cellular component - APPL1 26060 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 cytosol Cellular component 17848569 PKP4 8502 plakophilin 4 cell-cell contact zone Cellular component 22965878 GSK3B 2932 glycogen synthase kinase 3 beta negative regulation of canonical Wnt signaling pathway Biological process 19366350 AVPR1A 552 arginine vasopressin receptor 1A positive regulation of cell growth Biological process - AHNAK 79026 AHNAK nucleoprotein extracellular exosome Cellular component 19056867 PM20D2 135293 peptidase M20 domain containing 2 hydrolase activity Molecular function - CHST11 50515 carbohydrate (chondroitin 4) sulfotransferase 11 post-embryonic development Biological process - BCKDHA 593 branched chain keto acid dehydrogenase E1, alpha polypeptide mitochondrial alpha-ketoglutarate dehydrogenase complex Cellular component 7883996 CARD16 114769 caspase recruitment domain family, member 16 regulation of apoptotic process Biological process - CNTN2 6900 contactin 2 (axonal) presynaptic membrane organization Biological process 23518707 KAT2A 2648 K(lysine) acetyltransferase 2A regulation of mitochondrion degradation Biological process 24912190 ERVK-6 64006 endogenous retrovirus group K, member 6 mRNA transport Biological process - IGFBP5 3488 insulin-like growth factor binding protein 5 extracellular space Cellular component - ADSL 158 adenylosuccinate lyase protein tetramerization Biological process 16973378 DDIT3 1649 DNA-damage-inducible transcript 3 transcription regulatory region sequence-specific DNA binding Molecular function 24939851 NSD1 64324 nuclear receptor binding SET domain protein 1 histone H3-K36 methylation Biological process - APOA2 336 apolipoprotein A-II acute inflammatory response Biological process - ATAT1 79969 alpha tubulin acetyltransferase 1 focal adhesion Cellular component - NME3 4832 NME/NM23 nucleoside diphosphate kinase 3 nucleoside triphosphate biosynthetic process Biological process - NEDD4 4734 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase ubiquitin ligase complex Cellular component - AKAP17A 8227 A kinase (PRKA) anchor protein 17A B cell activation Biological process 1438229 MLXIPL 51085 MLX interacting protein-like cellular response to carbohydrate stimulus Biological process - PPP1R15A 23645 protein phosphatase 1, regulatory subunit 15A cellular response to DNA damage stimulus Biological process 9153226 CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 hepatocyte differentiation Biological process - ZFYVE21 79038 zinc finger, FYVE domain containing 21 protein binding Molecular function 25416956 NIF3L1 60491 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) nucleus Cellular component - RCL1 10171 RNA terminal phosphate cyclase-like 1 RNA-3'-phosphate cyclase activity Molecular function - NDEL1 81565 nudE neurodevelopment protein 1-like 1 nucleolus Cellular component - UBE2O 63893 ubiquitin-conjugating enzyme E2O poly(A) RNA binding Molecular function 22681889 GALNT3 2591 polypeptide N-acetylgalactosaminyltransferase 3 Golgi cisterna membrane Cellular component - DOCK4 9732 dedicator of cytokinesis 4 cell chemotaxis Biological process 20679435 YWHAB 7529 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta cytosol Cellular component - PDXK 8566 pyridoxal (pyridoxine, vitamin B6) kinase ATP binding Molecular function 16600635 HOOK3 84376 hook microtubule-tethering protein 3 negative regulation of neurogenesis Biological process - HOXA2 3199 homeobox A2 cell fate determination Biological process - ISL2 64843 ISL LIM homeobox 2 regulation of transcription, DNA-templated Biological process - ZBTB24 9841 zinc finger and BTB domain containing 24 hematopoietic progenitor cell differentiation Biological process - PMAIP1 5366 phorbol-12-myristate-13-acetate-induced protein 1 cellular response to hypoxia Biological process 14699081 NF1 4763 neurofibromin 1 smooth muscle tissue development Biological process - P2RX6 9127 purinergic receptor P2X, ligand gated ion channel, 6 ion transmembrane transport Biological process - PMS2P1 5379 postmeiotic segregation increased 2 pseudogene 1 kinase activity Molecular function - USH1C 10083 Usher syndrome 1C (autosomal recessive, severe) cytoskeleton Cellular component - ASF1A 25842 anti-silencing function 1A histone chaperone protein binding Molecular function 19862764 CREB1 1385 cAMP responsive element binding protein 1 positive regulation of osteoclast differentiation Biological process - GFM2 84340 G elongation factor, mitochondrial 2 organelle organization Biological process - ACVR1B 91 activin A receptor, type IB development of primary female sexual characteristics Biological process - ADA 100 adenosine deaminase plasma membrane Cellular component - NEUROD2 4761 neuronal differentiation 2 nervous system development Biological process 8816493 IGHG1 3500 immunoglobulin heavy constant gamma 1 (G1m marker) extracellular exosome Cellular component 23376485 KLHL17 339451 kelch-like family member 17 actin cytoskeleton organization Biological process - NSMCE2 286053 non-SMC element 2, MMS21 homolog (S. cerevisiae) protein binding Molecular function 18086888 MYL6 4637 myosin, light chain 6, alkali, smooth muscle and non-muscle calcium ion binding Molecular function - C1QTNF2 114898 C1q and tumor necrosis factor related protein 2 receptor binding Molecular function - VTI1B 10490 vesicle transport through interaction with t-SNAREs 1B intracellular membrane-bounded organelle Cellular component - LLGL2 3993 lethal giant larvae homolog 2 (Drosophila) protein binding Molecular function 12725730 DNM1L 10059 dynamin 1-like lipid binding Molecular function - DTL 51514 denticleless E3 ubiquitin protein ligase homolog (Drosophila) cellular response to DNA damage stimulus Biological process 20129063 HIST2H4A 8370 histone cluster 2, H4a poly(A) RNA binding Molecular function 22658674 FITM1 161247 fat storage-inducing transmembrane protein 1 phospholipid biosynthetic process Biological process - SKAP1 8631 src kinase associated phosphoprotein 1 positive regulation of signal transduction Biological process 9195899 PICALM 8301 phosphatidylinositol binding clathrin assembly protein cell proliferation Biological process 22952941 CPEB4 80315 cytoplasmic polyadenylation element binding protein 4 ionotropic glutamate receptor signaling pathway Biological process - NUDT22 84304 nudix (nucleoside diphosphate linked moiety X)-type motif 22 hydrolase activity Molecular function - OR4C46 119749 olfactory receptor, family 4, subfamily C, member 46 G-protein coupled receptor signaling pathway Biological process - ITGB2 3689 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) integrin-mediated signaling pathway Biological process 12885943 RFC1 5981 replication factor C (activator 1) 1, 145kDa error-prone translesion synthesis Biological process - TGFB2 7042 transforming growth factor, beta 2 generation of neurons Biological process 15944186 DLAT 1737 dihydrolipoamide S-acetyltransferase small molecule metabolic process Biological process - LZTFL1 54585 leucine zipper transcription factor-like 1 negative regulation of protein localization to ciliary membrane Biological process 22072986 CLLU1 574028 chronic lymphocytic leukemia up-regulated 1 cytoplasm Cellular component - ALAS2 212 5'-aminolevulinate synthase 2 protoporphyrinogen IX biosynthetic process Biological process - CTSS 1520 cathepsin S extracellular region Cellular component - HNRNPM 4670 heterogeneous nuclear ribonucleoprotein M integral component of plasma membrane Cellular component 8088785 HIP1 3092 huntingtin interacting protein 1 clathrin binding Molecular function 11577110 HYAL2 8692 hyaluronoglucosaminidase 2 transforming growth factor beta binding Molecular function - HLA-DRB4 3126 major histocompatibility complex, class II, DR beta 4 T cell receptor signaling pathway Biological process - EGFR 1956 epidermal growth factor receptor positive regulation of DNA replication Biological process 17115032 CHUK 1147 conserved helix-loop-helix ubiquitous kinase lactation Biological process - HSF1 3297 heat shock transcription factor 1 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 8926278 PSMD12 5718 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 positive regulation of canonical Wnt signaling pathway Biological process - DMGDH 29958 dimethylglycine dehydrogenase poly(A) RNA binding Molecular function 22658674 IL2RA 3559 interleukin 2 receptor, alpha cell proliferation Biological process 2983318 ZMIZ1 57178 zinc finger, MIZ-type containing 1 nuclear speck Cellular component - POLR2E 5434 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa transcription from RNA polymerase II promoter Biological process - CYP1A2 1544 cytochrome P450, family 1, subfamily A, polypeptide 2 monoterpenoid metabolic process Biological process 16401082 MAPK8 5599 mitogen-activated protein kinase 8 stress-activated MAPK cascade Biological process - PATE3 100169851 prostate and testis expressed 3 extracellular region Cellular component - SYMPK 8189 symplekin protein binding Molecular function 18688255 RTCB 51493 RNA 2',3'-cyclic phosphate and 5'-OH ligase nucleus Cellular component 24608264 TBX2 6909 T-box 2 developmental growth involved in morphogenesis Biological process - FAM126A 84668 family with sequence similarity 126, member A biological_process Biological process - MBNL1 4154 muscleblind-like splicing regulator 1 in utero embryonic development Biological process - RERGL 79785 RERG/RAS-like membrane Cellular component - FFAR4 338557 free fatty acid receptor 4 peptide binding Molecular function - STRN 6801 striatin, calmodulin binding protein negative regulation of cell proliferation Biological process 18502210 PLRG1 5356 pleiotropic regulator 1 protein binding Molecular function 20176811 DUOX1 53905 dual oxidase 1 response to oxidative stress Biological process - TRAPPC2L 51693 trafficking protein particle complex 2-like ER to Golgi vesicle-mediated transport Biological process - Mar-02 54996 mitochondrial amidoxime reducing component 2 mitochondrial outer membrane Cellular component - ALPK2 115701 alpha-kinase 2 nucleoplasm Cellular component - SEC24D 9871 SEC24 family member D COPII vesicle coat Cellular component 10329445 SIRT7 51547 sirtuin 7 histone H4 deacetylation Biological process 22722849 YWHAH 7533 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta transcription initiation from RNA polymerase II promoter Biological process - PRMT7 54496 protein arginine methyltransferase 7 nucleus Cellular component - ATG7 10533 autophagy related 7 cytoplasm Cellular component 20543840 EXOSC9 5393 exosome component 9 cytoplasm Cellular component 17545563 KRT14 3861 keratin 14, type I aging Biological process 21916889 XRCC6 2547 X-ray repair complementing defective repair in Chinese hamster cells 6 double-strand break repair via nonhomologous end joining Biological process 15824061 UTP14A 10813 UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) nucleolus Cellular component - ARID4A 5926 AT rich interactive domain 4A (RBP1-like) chromatin organization Biological process - TXNL4A 10907 thioredoxin-like 4A protein binding Molecular function 15840814 TGFBR2 7048 transforming growth factor, beta receptor II (70/80kDa) lens fiber cell apoptotic process Biological process - ANGPT2 285 angiopoietin 2 leukocyte migration Biological process - UBC 7316 ubiquitin C positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Biological process - RNF2 6045 ring finger protein 2 mitotic cell cycle Biological process - EFTUD2 9343 elongation factor Tu GTP binding domain containing 2 GTP binding Molecular function - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa liver development Biological process - ARG1 383 arginase 1 arginase activity Molecular function - OMD 4958 osteomodulin keratan sulfate metabolic process Biological process - SRRM4 84530 serine/arginine repetitive matrix 4 nucleus Cellular component - TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) protein heterodimerization activity Molecular function 11505339 AQP4 361 aquaporin 4 water transmembrane transporter activity Molecular function 7559426 EHD3 30845 EH-domain containing 3 protein homooligomerization Biological process 17233914 MAPK1 5594 mitogen-activated protein kinase 1 regulation of cytoskeleton organization Biological process 19565474 PPA2 27068 pyrophosphatase (inorganic) 2 gene expression Biological process - SERPINF1 5176 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 cellular response to cobalt ion Biological process - OR6N1 128372 olfactory receptor, family 6, subfamily N, member 1 G-protein coupled receptor activity Molecular function - INTS7 25896 integrator complex subunit 7 integrator complex Cellular component 16239144 OXTR 5021 oxytocin receptor integral component of plasma membrane Cellular component 10858434 RHCG 51458 Rh family, C glycoprotein extracellular exosome Cellular component 19056867 EREG 2069 epiregulin female meiotic division Biological process - GAPT 202309 GRB2-binding adaptor protein, transmembrane immunoglobulin production involved in immunoglobulin mediated immune response Biological process - NUAK2 81788 NUAK family, SNF1-like kinase, 2 AMP-activated protein kinase complex Cellular component - KCNG1 3755 potassium channel, voltage gated modifier subfamily G, member 1 regulation of ion transmembrane transport Biological process - CCL8 6355 chemokine (C-C motif) ligand 8 cell Cellular component 10734056 CAMLG 819 calcium modulating ligand defense response Biological process 7522304 MARK1 4139 MAP/microtubule affinity-regulating kinase 1 cytoskeleton organization Biological process - PROX1 5629 prospero homeobox 1 lens development in camera-type eye Biological process 8812486 PPP3R1 5534 protein phosphatase 3, regulatory subunit B, alpha protein binding Molecular function 16648474 RAP1B 5908 RAP1B, member of RAS oncogene family extracellular exosome Cellular component 19199708 FBXO45 200933 F-box protein 45 corticospinal tract morphogenesis Biological process - RPS11 6205 ribosomal protein S11 nucleolus Cellular component 16791210 TRIM16 10626 tripartite motif containing 16 positive regulation of interleukin-1 beta secretion Biological process 16575408 PHF21A 51317 PHD finger protein 21A zinc ion binding Molecular function - CRHBP 1393 corticotropin releasing hormone binding protein learning or memory Biological process 7477348 KIAA0101 9768 KIAA0101 DNA replication Biological process 23000965 INPP5K 51763 inositol polyphosphate-5-phosphatase K perinuclear region of cytoplasm Cellular component 18774950 VHL 7428 von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase enzyme binding Molecular function 11641274 APELA 100506013 apelin receptor early endogenous ligand mesendoderm migration Biological process - ATP6V0B 533 ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b transferrin transport Biological process - DERL1 79139 derlin 1 protease binding Molecular function 25239945 PRKACA 5566 protein kinase, cAMP-dependent, catalytic, alpha peptidyl-serine phosphorylation Biological process 10805756 PITX2 5308 paired-like homeodomain 2 cardiac neural crest cell migration involved in outflow tract morphogenesis Biological process - SECISBP2 79048 SECIS binding protein 2 nucleoplasm Cellular component - C5orf30 90355 chromosome 5 open reading frame 30 protein binding Molecular function 22085962 BNC1 646 basonuclin 1 epidermis development Biological process 1332044 CYR61 3491 cysteine-rich, angiogenic inducer, 61 positive regulation of osteoblast differentiation Biological process 20675382 DAP3 7818 death associated protein 3 mitochondrial translational initiation Biological process - CAV3 859 caveolin 3 regulation of p38MAPK cascade Biological process - STAB1 23166 stabilin 1 hyaluronic acid binding Molecular function - TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4) RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - AWAT1 158833 acyl-CoA wax alcohol acyltransferase 1 lipid metabolic process Biological process - RAPGEF4 11069 Rap guanine nucleotide exchange factor (GEF) 4 Ras GTPase binding Molecular function - HOXA1 3198 homeobox A1 cochlea development Biological process 16155570 MAP2K3 5606 mitogen-activated protein kinase kinase 3 signal transduction by protein phosphorylation Biological process - RNASE6 6039 ribonuclease, RNase A family, k6 defense response Biological process 8836175 PIK3R6 146850 phosphoinositide-3-kinase, regulatory subunit 6 membrane Cellular component - MTF2 22823 metal response element binding transcription factor 2 chromatin modification Biological process - ABCC9 10060 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 voltage-gated potassium channel complex Cellular component 20610380 TTLL5 23093 tubulin tyrosine ligase-like family member 5 cilium Cellular component - HSPA1A 3303 heat shock 70kDa protein 1A virus receptor activity Molecular function - OR4F3 26683 olfactory receptor, family 4, subfamily F, member 3 olfactory receptor activity Molecular function - CARD9 64170 caspase recruitment domain family, member 9 response to drug Biological process - BCL3 602 B-cell CLL/lymphoma 3 regulation of NF-kappaB import into nucleus Biological process 8196632 PCSK9 255738 proprotein convertase subtilisin/kexin type 9 positive regulation of low-density lipoprotein particle receptor catabolic process Biological process 22848640 GOLGA4 2803 golgin A4 nucleoplasm Cellular component - HSPG2 3339 heparan sulfate proteoglycan 2 Golgi lumen Cellular component - MTSS1L 92154 metastasis suppressor 1-like actin binding Molecular function - DUSP8 1850 dual specificity phosphatase 8 nucleus Cellular component - CYP1B1 1545 cytochrome P450, family 1, subfamily B, polypeptide 1 endoplasmic reticulum membrane Cellular component - C4B 721 complement component 4B (Chido blood group) regulation of complement activation Biological process - ANGPT2 285 angiopoietin 2 extracellular space Cellular component 9660821 PLCG2 5336 phospholipase C, gamma 2 (phosphatidylinositol-specific) phospholipase C activity Molecular function - HCRTR1 3061 hypocretin (orexin) receptor 1 peptide binding Molecular function - RPA3 6119 replication protein A3, 14kDa DNA replication factor A complex Cellular component 11927569 BCL2 596 B-cell CLL/lymphoma 2 endoplasmic reticulum calcium ion homeostasis Biological process 18309324 SCG2 7857 secretogranin II secretory granule Cellular component - SHROOM3 57619 shroom family member 3 regulation of cell shape Biological process - SPTBN2 6712 spectrin, beta, non-erythrocytic 2 cytoplasm Cellular component - EXT2 2132 exostosin glycosyltransferase 2 membrane Cellular component 19946888 MINPP1 9562 multiple inositol-polyphosphate phosphatase 1 endoplasmic reticulum lumen Cellular component - TOR1A 1861 torsin family 1, member A (torsin A) intracellular membrane-bounded organelle Cellular component - DYNC2LI1 51626 dynein, cytoplasmic 2, light intermediate chain 1 antigen processing and presentation of exogenous peptide antigen via MHC class II Biological process - SCARB1 949 scavenger receptor class B, member 1 microvillus membrane Cellular component - CBX5 23468 chromobox homolog 5 protein binding, bridging Molecular function - UTY 7404 ubiquitously transcribed tetratricopeptide repeat containing, Y-linked nucleus Cellular component - TAOK3 51347 TAO kinase 3 negative regulation of protein kinase activity Biological process 10559204 ZNF812 729648 zinc finger protein 812 metal ion binding Molecular function - TLR2 7097 toll-like receptor 2 negative regulation of interleukin-12 production Biological process - MAN2A1 4124 mannosidase, alpha, class 2A, member 1 cellular protein metabolic process Biological process - GNAS 2778 GNAS complex locus water transport Biological process - TINAG 27283 tubulointerstitial nephritis antigen receptor-mediated endocytosis Biological process - TUFM 7284 Tu translation elongation factor, mitochondrial poly(A) RNA binding Molecular function 22658674 PCDHA10 56139 protocadherin alpha 10 integral component of plasma membrane Cellular component 10380929 USP17L10 100287144 ubiquitin specific peptidase 17-like family member 10 nucleus Cellular component - ABCC9 10060 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 ATP binding Molecular function - CD164 8763 CD164 molecule, sialomucin integral component of plasma membrane Cellular component 11027692 ENG 2022 endoglin extracellular matrix disassembly Biological process 18223685 EDN3 1908 endothelin 3 cell surface receptor signaling pathway Biological process 1713452 MARVELD1 83742 MARVEL domain containing 1 cytoskeleton Cellular component - TENM3 55714 teneurin transmembrane protein 3 protein homodimerization activity Molecular function - ABI2 10152 abl-interactor 2 cytoplasm Cellular component 8649853 HOXA2 3199 homeobox A2 middle ear morphogenesis Biological process - ACP1 52 acid phosphatase 1, soluble protein binding Molecular function 15846844 GALNT1 2589 polypeptide N-acetylgalactosaminyltransferase 1 polypeptide N-acetylgalactosaminyltransferase activity Molecular function 9295285 FOXS1 2307 forkhead box S1 positive regulation of multicellular organism growth Biological process - AKR1C1 1645 aldo-keto reductase family 1, member C1 xenobiotic metabolic process Biological process 8486699 ACAT1 38 acetyl-CoA acetyltransferase 1 branched-chain amino acid catabolic process Biological process - SNRPF 6636 small nuclear ribonucleoprotein polypeptide F nucleoplasm Cellular component - POU1F1 5449 POU class 1 homeobox 1 positive regulation of transcription, DNA-templated Biological process 9482665 ARHGAP24 83478 Rho GTPase activating protein 24 regulation of small GTPase mediated signal transduction Biological process - MMP3 4314 matrix metallopeptidase 3 collagen catabolic process Biological process - UGT1A4 54657 UDP glucuronosyltransferase 1 family, polypeptide A4 endoplasmic reticulum membrane Cellular component - HSPD1 3329 heat shock 60kDa protein 1 (chaperonin) positive regulation of macrophage activation Biological process 17164250 GSTO2 119391 glutathione S-transferase omega 2 glutathione transferase activity Molecular function - RBBP6 5930 retinoblastoma binding protein 6 somite development Biological process - SNAP29 9342 synaptosomal-associated protein, 29kDa protein transport Biological process - GEMIN6 79833 gem (nuclear organelle) associated protein 6 cytoplasm Cellular component 11748230 IGF2BP1 10642 insulin-like growth factor 2 mRNA binding protein 1 dendritic spine Cellular component - BAIAP2 10458 BAI1-associated protein 2 identical protein binding Molecular function 11696321 PDK3 5165 pyruvate dehydrogenase kinase, isozyme 3 mitochondrion Cellular component 7499431 PHF5A 84844 PHD finger protein 5A U12-type spliceosomal complex Cellular component 15146077 HDGFRP2 84717 hepatoma-derived growth factor-related protein 2 DNA binding Molecular function - RNF2 6045 ring finger protein 2 protein binding Molecular function 10369680 KIF16B 55614 kinesin family member 16B early endosome to late endosome transport Biological process 15882625 ERBB2 2064 erb-b2 receptor tyrosine kinase 2 positive regulation of protein phosphorylation Biological process - BCS1L 617 BC1 (ubiquinol-cytochrome c reductase) synthesis-like ATP binding Molecular function - PGR 5241 progesterone receptor receptor binding Molecular function 12771131 RXFP4 339403 relaxin/insulin-like family peptide receptor 4 integral component of membrane Cellular component - DDB1 1642 damage-specific DNA binding protein 1, 127kDa negative regulation of apoptotic process Biological process - SKA2 348235 spindle and kinetochore associated complex subunit 2 chromosome segregation Biological process 19289083 ZNF621 285268 zinc finger protein 621 metal ion binding Molecular function - PDPK1 5170 3-phosphoinositide dependent protein kinase 1 actin cytoskeleton organization Biological process 10792047 GTF2H3 2967 general transcription factor IIH, polypeptide 3, 34kDa transcription from RNA polymerase II promoter Biological process - TMPRSS9 360200 transmembrane protease, serine 9 integral component of plasma membrane Cellular component - RPS6KB1 6198 ribosomal protein S6 kinase, 70kDa, polypeptide 1 perinuclear region of cytoplasm Cellular component - ALDH1L1 10840 aldehyde dehydrogenase 1 family, member L1 hydroxymethyl-, formyl- and related transferase activity Molecular function - RNF170 81790 ring finger protein 170 ligase activity Molecular function - OGG1 4968 8-oxoguanine DNA glycosylase microtubule binding Molecular function - VIL1 7429 villin 1 cellular response to hepatocyte growth factor stimulus Biological process - OMD 4958 osteomodulin regulation of bone mineralization Biological process - AHCTF1 25909 AT hook containing transcription factor 1 mRNA transport Biological process - AK7 122481 adenylate kinase 7 ATP binding Molecular function - DNASE2B 58511 deoxyribonuclease II beta apoptotic DNA fragmentation Biological process - UHRF2 115426 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase ligase activity Molecular function - DYSF 8291 dysferlin vesicle fusion Biological process - DNAJC5 80331 DnaJ (Hsp40) homolog, subfamily C, member 5 membrane Cellular component 19946888 PMEPA1 56937 prostate transmembrane protein, androgen induced 1 R-SMAD binding Molecular function 20129061 SLC6A3 6531 solute carrier family 6 (neurotransmitter transporter), member 3 prepulse inhibition Biological process - SEH1L 81929 SEH1-like (S. cerevisiae) cytokine-mediated signaling pathway Biological process - EXT2 2132 exostosin glycosyltransferase 2 protein heterodimerization activity Molecular function 12907669 EIF3A 8661 eukaryotic translation initiation factor 3, subunit A cellular protein metabolic process Biological process - GNAI2 2771 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 regulation of calcium ion transport Biological process - GDNF 2668 glial cell derived neurotrophic factor regulation of stem cell differentiation Biological process 23626767 TNP2 7142 transition protein 2 (during histone to protamine replacement) spermatogenesis Biological process - FGD1 2245 FYVE, RhoGEF and PH domain containing 1 cytoskeleton Cellular component - RPL28 6158 ribosomal protein L28 SRP-dependent cotranslational protein targeting to membrane Biological process - JAGN1 84522 jagunal homolog 1 (Drosophila) protein transport Biological process - ZDHHC14 79683 zinc finger, DHHC-type containing 14 zinc ion binding Molecular function - ZNF25 219749 zinc finger protein 25 regulation of transcription, DNA-templated Biological process - SLC14A1 6563 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) water transport Biological process - CDK18 5129 cyclin-dependent kinase 18 cellular_component Cellular component - TTC23L 153657 tetratricopeptide repeat domain 23-like protein binding Molecular function 22458338 FAM129B 64855 family with sequence similarity 129, member B extracellular exosome Cellular component 19056867 ACSL4 2182 acyl-CoA synthetase long-chain family member 4 cellular lipid metabolic process Biological process - CARTPT 9607 CART prepropeptide positive regulation of blood pressure Biological process 11711504 PPIA 5478 peptidylprolyl isomerase A (cyclophilin A) uncoating of virus Biological process - YME1L1 10730 YME1-like 1 ATPase misfolded or incompletely synthesized protein catabolic process Biological process 22262461 ZBTB47 92999 zinc finger and BTB domain containing 47 transcription, DNA-templated Biological process - NAA15 80155 N(alpha)-acetyltransferase 15, NatA auxiliary subunit cell differentiation Biological process - HSPB9 94086 heat shock protein, alpha-crystallin-related, B9 protein binding Molecular function 15503857 NR1H2 7376 nuclear receptor subfamily 1, group H, member 2 positive regulation of cholesterol transport Biological process 16141411 CDYL 9425 chromodomain protein, Y-like spermatogenesis Biological process 10192397 RHOXF1 158800 Rhox homeobox family, member 1 gamete generation Biological process 11980563 BIRC5 332 baculoviral IAP repeat containing 5 establishment of chromosome localization Biological process 12805209 ROPN1B 152015 rhophilin associated tail protein 1B protein heterodimerization activity Molecular function 11278869 HLA-A 3105 major histocompatibility complex, class I, A endoplasmic reticulum exit site Cellular component 20946353 CYBA 1535 cytochrome b-245, alpha polypeptide cytochrome complex assembly Biological process 7938008 MAP3K7 6885 mitogen-activated protein kinase kinase kinase 7 JNK cascade Biological process - POLR2G 5436 polymerase (RNA) II (DNA directed) polypeptide G cytoplasmic mRNA processing body Cellular component - CENPF 1063 centromere protein F, 350/400kDa protein binding Molecular function 17043677 CDH1 999 cadherin 1, type 1, E-cadherin (epithelial) cellular response to indole-3-methanol Biological process 10868478 ADD1 118 adducin 1 (alpha) actin filament bundle assembly Biological process 3693401 SLC51B 123264 solute carrier family 51, beta subunit plasma membrane Cellular component 12719432 EHHADH 1962 enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase internal protein amino acid acetylation Biological process 20167786 DFNA5 1687 deafness, autosomal dominant 5 sensory perception of sound Biological process 9771715 CGRRF1 10668 cell growth regulator with ring finger domain 1 negative regulation of cell proliferation Biological process 8968090 UGT2B4 7363 UDP glucuronosyltransferase 2 family, polypeptide B4 cellular glucuronidation Biological process 20056724 KRT6A 3853 keratin 6A, type II activation of mitophagy in response to mitochondrial depolarization Biological process 22020285 TSSK3 81629 testis-specific serine kinase 3 ATP binding Molecular function - PDGFB 5155 platelet-derived growth factor beta polypeptide metanephric glomerular endothelium development Biological process - GCLC 2729 glutamate-cysteine ligase, catalytic subunit response to heat Biological process 8104187 SEC14L6 730005 SEC14-like 6 (S. cerevisiae) intracellular Cellular component - TP53 7157 tumor protein p53 endoplasmic reticulum Cellular component - JDP2 122953 Jun dimerization protein 2 protein heterodimerization activity Molecular function - DAGLB 221955 diacylglycerol lipase, beta lipid catabolic process Biological process - SGCG 6445 sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) muscle organ development Biological process 8641426 CACNA2D4 93589 calcium channel, voltage-dependent, alpha 2/delta subunit 4 regulation of ion transmembrane transport Biological process - BEX1 55859 brain expressed, X-linked 1 positive regulation of transcription from RNA polymerase II promoter Biological process 16314316 CHRNA7 1139 cholinergic receptor, nicotinic, alpha 7 (neuronal) response to nicotine Biological process 12189247 APC 324 adenomatous polyposis coli cytoplasm Cellular component 11035805 MBNL1 4154 muscleblind-like splicing regulator 1 double-stranded RNA binding Molecular function 10970838 TBX2 6909 T-box 2 negative regulation of heart looping Biological process - RXRA 6256 retinoid X receptor, alpha maternal placenta development Biological process - MTSS1 9788 metastasis suppressor 1 negative regulation of epithelial cell proliferation Biological process - NKX3-1 4824 NK3 homeobox 1 nucleus Cellular component 11137288 RPS3 6188 ribosomal protein S3 membrane Cellular component 19946888 PRAMEF17 391004 PRAME family member 17 positive regulation of cell proliferation Biological process - PCSK1N 27344 proprotein convertase subtilisin/kexin type 1 inhibitor response to cold Biological process - UPK3A 7380 uroplakin 3A kidney development Biological process - FOXO3 2309 forkhead box O3 DNA damage response, signal transduction by p53 class mediator Biological process - PER3 8863 period circadian clock 3 protein binding Molecular function 21070773 POLR2C 5432 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa mRNA splicing, via spliceosome Biological process - KIFC1 3833 kinesin family member C1 microtubule Cellular component - ATF4 468 activating transcription factor 4 regulation of transcription, DNA-templated Biological process - TYMS 7298 thymidylate synthetase G1/S transition of mitotic cell cycle Biological process - HELLS 3070 helicase, lymphoid-specific transcription, DNA-templated Biological process - FUBP1 8880 far upstream element (FUSE) binding protein 1 positive regulation of gene expression Biological process 19087307 DUSP16 80824 dual specificity phosphatase 16 MAPK export from nucleus Biological process 11489891 ERCC2 2068 excision repair cross-complementation group 2 nucleoplasm Cellular component - ZXDA 7789 zinc finger, X-linked, duplicated A positive regulation of transcription, DNA-templated Biological process 17493635 FOXO3 2309 forkhead box O3 cell differentiation Biological process - VTN 7448 vitronectin positive regulation of cell-substrate adhesion Biological process - TENM1 10178 teneurin transmembrane protein 1 regulation of transcription from RNA polymerase III promoter Biological process - CYP8B1 1582 cytochrome P450, family 8, subfamily B, polypeptide 1 xenobiotic metabolic process Biological process - ENOX2 10495 ecto-NOX disulfide-thiol exchanger 2 nucleic acid binding Molecular function - HNRNPA0 10949 heterogeneous nuclear ribonucleoprotein A0 mRNA processing Biological process 7585247 CCNB1 891 cyclin B1 histone kinase activity Molecular function - DICER1 23405 dicer 1, ribonuclease type III pre-miRNA binding Molecular function 18178619 NR0B2 8431 nuclear receptor subfamily 0, group B, member 2 sequence-specific DNA binding transcription factor activity Molecular function - FANCG 2189 Fanconi anemia, complementation group G response to radiation Biological process - DIXDC1 85458 DIX domain containing 1 positive regulation of canonical Wnt signaling pathway Biological process 21189423 MRPL45 84311 mitochondrial ribosomal protein L45 mitochondrion Cellular component - MICALL1 85377 MICAL-like 1 zinc ion binding Molecular function - NIN 51199 ninein (GSK3B interacting protein) centrosome localization Biological process 16154161 FAM189A2 9413 family with sequence similarity 189, member A2 biological_process Biological process - SOX2 6657 SRY (sex determining region Y)-box 2 somatic stem cell maintenance Biological process - LRMP 4033 lymphoid-restricted membrane protein integral component of endoplasmic reticulum membrane Cellular component - DAZL 1618 deleted in azoospermia-like germ cell development Biological process 9288969 STAP1 26228 signal transducing adaptor family member 1 cytoplasm Cellular component 17936702 AGTPBP1 23287 ATP/GTP binding protein 1 zinc ion binding Molecular function - CHP1 11261 calcineurin-like EF-hand protein 1 cytosol Cellular component - C1QTNF1 114897 C1q and tumor necrosis factor related protein 1 protein homooligomerization Biological process - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa cell-cell junction Cellular component 19151727 MAN2A1 4124 mannosidase, alpha, class 2A, member 1 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Molecular function - ULBP3 79465 UL16 binding protein 3 peptide antigen binding Molecular function - PROM2 150696 prominin 2 cholesterol binding Molecular function 12514187 SF3B1 23451 splicing factor 3b, subunit 1, 155kDa spliceosomal complex Cellular component 9585501 CACNA2D2 9254 calcium channel, voltage-dependent, alpha 2/delta subunit 2 neuromuscular junction development Biological process - ADCK4 79934 aarF domain containing kinase 4 plasma membrane Cellular component - AHNAK 79026 AHNAK nucleoprotein plasma membrane Cellular component 21940993 FAM90A15P 389630 putative protein FAM90A15 zinc ion binding Molecular function - UBC 7316 ubiquitin C negative regulation of epidermal growth factor receptor signaling pathway Biological process - USP28 57646 ubiquitin specific peptidase 28 response to ionizing radiation Biological process 16901786 GHR 2690 growth hormone receptor protein kinase binding Molecular function - MYH9 4627 myosin, heavy chain 9, non-muscle myosin II complex Cellular component 24072716 FADS2P1 643181 fatty acid desaturase 2 pseudogene 1 integral component of membrane Cellular component - C2CD3 26005 C2 calcium-dependent domain containing 3 organelle organization Biological process - SIX4 51804 SIX homeobox 4 transcription, DNA-templated Biological process - HSPA1B 3304 heat shock 70kDa protein 1B C3HC4-type RING finger domain binding Molecular function 25281747 MST1R 4486 macrophage stimulating 1 receptor positive regulation of protein kinase B signaling Biological process 12676986 TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) negative regulation of neuron apoptotic process Biological process - SPTB 6710 spectrin, beta, erythrocytic cytosol Cellular component - DHFRL1 200895 dihydrofolate reductase-like 1 nucleotide biosynthetic process Biological process - NKX3-1 4824 NK3 homeobox 1 negative regulation of cell proliferation Biological process 17486276 PTPRC 5788 protein tyrosine phosphatase, receptor type, C cell surface Cellular component 24337748 HSD17B4 3295 hydroxysteroid (17-beta) dehydrogenase 4 long-chain-enoyl-CoA hydratase activity Molecular function - PHC1 1911 polyhomeotic homolog 1 (Drosophila) cellular response to retinoic acid Biological process - NUDT21 11051 nudix (nucleoside diphosphate linked moiety X)-type motif 21 nucleus Cellular component 20695905 TMEM189 387521 transmembrane protein 189 protein ubiquitination Biological process - OPTC 26254 opticin extracellular matrix structural constituent Molecular function 10636917 NOTCH2 4853 notch 2 cell surface Cellular component 9244302 FDFT1 2222 farnesyl-diphosphate farnesyltransferase 1 steroid biosynthetic process Biological process 8474436 L1RE1 4029 LINE1 retrotransposable element 1 ribonucleoprotein complex Cellular component 16183655 C7orf60 154743 chromosome 7 open reading frame 60 rRNA methylation Biological process - F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 positive regulation of ERK1 and ERK2 cascade Biological process - PRPF19 27339 pre-mRNA processing factor 19 site of double-strand break Cellular component 18263876 VSX2 338917 visual system homeobox 2 positive regulation of transcription from RNA polymerase II promoter Biological process - CEL 1056 carboxyl ester lipase intestinal cholesterol absorption Biological process 12031288 NCF4 4689 neutrophil cytosolic factor 4, 40kDa immune response Biological process 8280052 RPL11 6135 ribosomal protein L11 viral life cycle Biological process - CCKAR 886 cholecystokinin A receptor forebrain development Biological process - OR1J1 347168 olfactory receptor, family 1, subfamily J, member 1 integral component of membrane Cellular component - RYR2 6262 ryanodine receptor 2 (cardiac) calmodulin binding Molecular function - CRIP1 1396 cysteine-rich protein 1 (intestinal) cell proliferation Biological process 9126610 NOD1 10392 nucleotide-binding oligomerization domain containing 1 protein homodimerization activity Molecular function 18186648 SDHB 6390 succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 4 iron, 4 sulfur cluster binding Molecular function - HS3ST3A1 9955 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 sulfotransferase activity Molecular function 9988767 NFKBIB 4793 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta signal transducer activity Molecular function 7776974 FGF12 2257 fibroblast growth factor 12 ion channel binding Molecular function 12401812 MED8 112950 mediator complex subunit 8 gene expression Biological process - GADD45B 4616 growth arrest and DNA-damage-inducible, beta regulation of cell cycle Biological process - MRPL44 65080 mitochondrial ribosomal protein L44 mitochondrial inner membrane Cellular component - RAB4A 5867 RAB4A, member RAS oncogene family insulin-responsive compartment Cellular component - PAX8 7849 paired box 8 pronephros development Biological process - TNFSF13 8741 tumor necrosis factor (ligand) superfamily, member 13 positive regulation of isotype switching to IgA isotypes Biological process 14988498 SRSF10 10772 serine/arginine-rich splicing factor 10 unfolded protein binding Molecular function 11684676 ODF2 4957 outer dense fiber of sperm tails 2 organelle organization Biological process - BBS9 27241 Bardet-Biedl syndrome 9 ciliary transition zone Cellular component 23943788 PPARA 5465 peroxisome proliferator-activated receptor alpha sequence-specific DNA binding transcription factor activity Molecular function - DHX15 1665 DEAH (Asp-Glu-Ala-His) box helicase 15 U2-type post-mRNA release spliceosomal complex Cellular component 19103666 PON2 5445 paraoxonase 2 nucleus Cellular component - TNRC6B 23112 trinucleotide repeat containing 6B Fc-epsilon receptor signaling pathway Biological process - DCTN5 84516 dynactin 5 (p25) protein binding Molecular function 25416956 ITGB1 3688 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) regulation of G-protein coupled receptor protein signaling pathway Biological process - DTNA 1837 dystrobrevin, alpha PDZ domain binding Molecular function - NDUFA10 4705 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa nucleotide biosynthetic process Biological process - CPT1C 126129 carnitine palmitoyltransferase 1C synapse Cellular component - PRICKLE1 144165 prickle homolog 1 (Drosophila) zinc ion binding Molecular function - PLEC 5339 plectin ankyrin binding Molecular function 21223964 EDDM3A 10876 epididymal protein 3A sperm displacement Biological process 7514008 ZNF584 201514 zinc finger protein 584 regulation of transcription, DNA-templated Biological process - SLC9A2 6549 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 regulation of pH Biological process - LRP4 4038 low density lipoprotein receptor-related protein 4 skeletal muscle acetylcholine-gated channel clustering Biological process - NOL3 8996 nucleolar protein 3 (apoptosis repressor with CARD domain) caspase binding Molecular function 15509781 TBP 6908 TATA box binding protein chromatin silencing at rDNA Biological process - RAB7A 7879 RAB7A, member RAS oncogene family phagosome-lysosome fusion Biological process 21255211 CDK5 1020 cyclin-dependent kinase 5 axon extension Biological process 21473899 MIA3 375056 melanoma inhibitory activity family, member 3 negative regulation of cell migration Biological process 17044017 PLS3 5358 plastin 3 cytoplasm Cellular component - SLC15A3 51296 solute carrier family 15 (oligopeptide transporter), member 3 peptide transport Biological process - REST 5978 RE1-silencing transcription factor cytosol Cellular component - CD248 57124 CD248 molecule, endosialin proteinaceous extracellular matrix Cellular component 10947988 SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 iron ion homeostasis Biological process - KIF26B 55083 kinesin family member 26B cytoplasm Cellular component - ATP8A2 51761 ATPase, aminophospholipid transporter, class I, type 8A, member 2 axonogenesis Biological process - MAP2K1 5604 mitogen-activated protein kinase kinase 1 labyrinthine layer development Biological process - UBB 7314 ubiquitin B translesion synthesis Biological process - LTA4H 4048 leukotriene A4 hydrolase metallopeptidase activity Molecular function - APOH 350 apolipoprotein H (beta-2-glycoprotein I) cell surface Cellular component 16480936 ADGRL3 23284 adhesion G protein-coupled receptor L3 integral component of membrane Cellular component 10994649 ABCB1 5243 ATP-binding cassette, sub-family B (MDR/TAP), member 1 transporter activity Molecular function 3022150 AREL1 9870 apoptosis resistant E3 ubiquitin protein ligase 1 ligase activity Molecular function - TANK 10010 TRAF family member-associated NFKB activator cytoplasm Cellular component - GNG2 54331 guanine nucleotide binding protein (G protein), gamma 2 cellular response to glucagon stimulus Biological process - HEYL 26508 hes-related family bHLH transcription factor with YRPW motif-like AF-1 domain binding Molecular function 21454491 PLK4 10733 polo-like kinase 4 deuterosome Cellular component - CAPRIN1 4076 cell cycle associated protein 1 positive regulation of dendritic spine morphogenesis Biological process - CLU 1191 clusterin protein binding Molecular function 16113678 BPIFB1 92747 BPI fold containing family B, member 1 extracellular region Cellular component 20237794 NLRC5 84166 NLR family, CARD domain containing 5 positive regulation of MHC class I biosynthetic process Biological process 20639463 SKI 6497 SKI proto-oncogene transcription corepressor activity Molecular function 12435627 CDC45 8318 cell division cycle 45 mitotic DNA replication preinitiation complex assembly Biological process - NDUFS4 4724 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) regulation of protein phosphorylation Biological process 11165261 CDC42EP3 10602 CDC42 effector protein (Rho GTPase binding) 3 GTP-Rho binding Molecular function - FETUB 26998 fetuin B extracellular exosome Cellular component 23533145 PDCD4 27250 programmed cell death 4 (neoplastic transformation inhibitor) RNA binding Molecular function - KCNB2 9312 potassium channel, voltage gated Shab related subfamily B, member 2 delayed rectifier potassium channel activity Molecular function - SLC38A4 55089 solute carrier family 38, member 4 integral component of plasma membrane Cellular component - NR2E3 10002 nuclear receptor subfamily 2, group E, member 3 negative regulation of transcription from RNA polymerase II promoter Biological process - OPA3 80207 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) mitochondrion morphogenesis Biological process - TAF6L 10629 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa histone H3 acetylation Biological process 11564863 PLD2 5338 phospholipase D2 phosphatidylglycerol biosynthetic process Biological process - MINK1 50488 misshapen-like kinase 1 extracellular exosome Cellular component 19056867 PURA 5813 purine-rich element binding protein A nuclear chromosome, telomeric region Cellular component 15777841 SYCP2 10388 synaptonemal complex protein 2 DNA binding Molecular function 10341103 KCNJ4 3761 potassium channel, inwardly rectifying subfamily J, member 4 protein binding Molecular function 16855024 PLAU 5328 plasminogen activator, urokinase extracellular region Cellular component - ERCC6 2074 excision repair cross-complementation group 6 multicellular organism growth Biological process - NEURL1 9148 neuralized E3 ubiquitin protein ligase 1 positive regulation of synapse maturation Biological process - CCNK 8812 cyclin K protein phosphorylation Biological process 9632813 FXR2 9513 fragile X mental retardation, autosomal homolog 2 cytoplasm Cellular component - TMBIM4 51643 transmembrane BAX inhibitor motif containing 4 protein binding Molecular function 19553469 TPI1 7167 triosephosphate isomerase 1 carbohydrate metabolic process Biological process - ATP5G2 517 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) integral component of membrane Cellular component - ICAM1 3383 intercellular adhesion molecule 1 plasma membrane Cellular component - MGAT4C 25834 MGAT4 family, member C integral component of membrane Cellular component - PLAUR 5329 plasminogen activator, urokinase receptor integral component of membrane Cellular component 1689240 NRP1 8829 neuropilin 1 angiogenesis Biological process 24401374 MMP9 4318 matrix metallopeptidase 9 proteinaceous extracellular matrix Cellular component - INPP4B 8821 inositol polyphosphate-4-phosphatase, type II, 105kDa cellular calcium ion homeostasis Biological process - IQGAP1 8826 IQ motif containing GTPase activating protein 1 positive regulation of GTPase activity Biological process 8051149 HIST1H2AC 8334 histone cluster 1, H2ac DNA binding Molecular function - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide positive regulation of phosphatidylinositol 3-kinase signaling Biological process 10734113 CYFIP1 23191 cytoplasmic FMR1 interacting protein 1 ruffle Cellular component - CD74 972 CD74 molecule, major histocompatibility complex, class II invariant chain positive regulation of type 2 immune response Biological process - HS3ST5 222537 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 glycosaminoglycan biosynthetic process Biological process - RTN4R 65078 reticulon 4 receptor protein binding Molecular function 20463223 HERC2 8924 HECT and RLD domain containing E3 ubiquitin protein ligase 2 spermatogenesis Biological process - SRPX2 27286 sushi-repeat containing protein, X-linked 2 receptor binding Molecular function 18718938 EPHA5 2044 EPH receptor A5 regulation of GTPase activity Biological process - IGF1R 3480 insulin-like growth factor 1 receptor positive regulation of cytokinesis Biological process - CAPN11 11131 calpain 11 cytoplasm Cellular component - FARSA 2193 phenylalanyl-tRNA synthetase, alpha subunit poly(A) RNA binding Molecular function 22681889 PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta mast cell granule Cellular component 20940048 GRIK2 2898 glutamate receptor, ionotropic, kainate 2 postsynaptic density Cellular component - GSTO2 119391 glutathione S-transferase omega 2 extracellular exosome Cellular component 19056867 PCNP 57092 PEST proteolytic signal containing nuclear protein protein binding Molecular function 12176013 FSCN2 25794 fascin actin-bundling protein 2, retinal cytoplasm Cellular component - CD1B 910 CD1b molecule immune response Biological process - ART4 420 ADP-ribosyltransferase 4 (Dombrock blood group) anchored component of membrane Cellular component - GNA13 10672 guanine nucleotide binding protein (G protein), alpha 13 in utero embryonic development Biological process - GABRD 2563 gamma-aminobutyric acid (GABA) A receptor, delta chloride channel activity Molecular function - TMED7 51014 transmembrane emp24 protein transport domain containing 7 COPI vesicle coat Cellular component 10359607 STX19 415117 syntaxin 19 integral component of membrane Cellular component - RCAN2 10231 regulator of calcineurin 2 cytoplasm Cellular component - EEF2 1938 eukaryotic translation elongation factor 2 polysome Cellular component - RBMY1F 159163 RNA binding motif protein, Y-linked, family 1, member F protein binding Molecular function 25416956 TXN 7295 thioredoxin cytosol Cellular component - SLC2A4RG 56731 SLC2A4 regulator nucleoplasm Cellular component - STAG2 10735 stromal antigen 2 membrane Cellular component 19946888 ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein Golgi apparatus Cellular component - SYVN1 84447 synovial apoptosis inhibitor 1, synoviolin ligase activity Molecular function - PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide platelet-derived growth factor beta-receptor activity Molecular function 2554309 NSG1 27065 neuron specific gene family member 1 Golgi membrane Cellular component - PACSIN2 11252 protein kinase C and casein kinase substrate in neurons 2 cytoplasmic vesicle membrane Cellular component - ARHGAP12 94134 Rho GTPase activating protein 12 morphogenesis of an epithelial sheet Biological process 23201090 FMR1NB 158521 fragile X mental retardation 1 neighbor nucleolus Cellular component - VPS37D 155382 vacuolar protein sorting 37 homolog D (S. cerevisiae) viral life cycle Biological process - VWA8 23078 von Willebrand factor A domain containing 8 metabolic process Biological process - AKAP6 9472 A kinase (PRKA) anchor protein 6 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Biological process - RALGAPA1 253959 Ral GTPase activating protein, alpha subunit 1 (catalytic) activation of GTPase activity Biological process - SMC1A 8243 structural maintenance of chromosomes 1A DNA repair Biological process 11877377 ERCC1 2067 excision repair cross-complementation group 1 response to nutrient Biological process - TRIM26 7726 tripartite motif containing 26 interferon-gamma-mediated signaling pathway Biological process - SPINK5 11005 serine peptidase inhibitor, Kazal type 5 negative regulation of endopeptidase activity Biological process - APBA3 9546 amyloid beta (A4) precursor protein-binding, family A, member 3 in utero embryonic development Biological process - VTA1 51534 vesicle (multivesicular body) trafficking 1 viral budding Biological process 15644320 MSGN1 343930 mesogenin 1 nucleus Cellular component - COL8A1 1295 collagen, type VIII, alpha 1 camera-type eye morphogenesis Biological process - STAMBP 10617 STAM binding protein ubiquitin-specific protease activity Molecular function 18388320 CTSS 1520 cathepsin S cellular response to thyroid hormone stimulus Biological process 21217776 ITK 3702 IL2-inducible T-cell kinase cytokine production Biological process - ABL2 27 ABL proto-oncogene 2, non-receptor tyrosine kinase ATP binding Molecular function - ZFP36 7538 ZFP36 ring finger protein response to starvation Biological process 15014438 KRIT1 889 KRIT1, ankyrin repeat containing negative regulation of endothelial cell migration Biological process 20616044 APLP1 333 amyloid beta (A4) precursor-like protein 1 negative regulation of cAMP biosynthetic process Biological process 16531006 OPTN 10133 optineurin recycling endosome Cellular component - RPS6KA1 6195 ribosomal protein S6 kinase, 90kDa, polypeptide 1 innate immune response Biological process - LMX1B 4010 LIM homeobox transcription factor 1, beta nucleus Cellular component 10767331 TSPY4 728395 testis specific protein, Y-linked 4 spermatogenesis Biological process - RQCD1 9125 RCD1 required for cell differentiation1 homolog (S. pombe) transcription, DNA-templated Biological process - PGLYRP2 114770 peptidoglycan recognition protein 2 membrane Cellular component 11461926 FTL 2512 ferritin, light polypeptide protein binding Molecular function 16169070 HLTF 6596 helicase-like transcription factor poly(A) RNA binding Molecular function 22658674 PSMB3 5691 proteasome (prosome, macropain) subunit, beta type, 3 stimulatory C-type lectin receptor signaling pathway Biological process - SOX11 6664 SRY (sex determining region Y)-box 11 translation factor activity, RNA binding Molecular function 10606637 YWHAG 7532 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma regulation of signal transduction Biological process 10433554 ARHGEF2 9181 Rho/Rac guanine nucleotide exchange factor (GEF) 2 vesicle Cellular component 21887730 JAK2 3717 Janus kinase 2 positive regulation of cell proliferation Biological process - SPN 6693 sialophorin chemotaxis Biological process 10753822 EXOC5 10640 exocyst complex component 5 membrane organization Biological process - RFWD2 64326 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase response to ionizing radiation Biological process 19805145 PSMD5 5711 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 stimulatory C-type lectin receptor signaling pathway Biological process - CTRB1 1504 chymotrypsinogen B1 extracellular space Cellular component - SP140 11262 SP140 nuclear body protein cytoplasm Cellular component - RNF133 168433 ring finger protein 133 zinc ion binding Molecular function - SPP1 6696 secreted phosphoprotein 1 inflammatory response Biological process - FBXL3 26224 F-box and leucine-rich repeat protein 3 circadian rhythm Biological process - RNF31 55072 ring finger protein 31 cytoplasmic side of plasma membrane Cellular component 20614026 HIST1H4L 8368 histone cluster 1, H4l nucleus Cellular component 14585971 HIST2H2BE 8349 histone cluster 2, H2be nucleosome assembly Biological process 1469070 PLSCR1 5359 phospholipid scramblase 1 calcium ion binding Molecular function 9218461 POLR3G 10622 polymerase (RNA) III (DNA directed) polypeptide G (32kD) transcription initiation from RNA polymerase III promoter Biological process - PSMD3 5709 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 programmed cell death Biological process - SOCS5 9655 suppressor of cytokine signaling 5 epidermal growth factor receptor binding Molecular function - SNRPD3 6634 small nuclear ribonucleoprotein D3 polypeptide 18kDa mRNA 3'-end processing Biological process - WNT9A 7483 wingless-type MMTV integration site family, member 9A negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process - KDM4A 9682 lysine (K)-specific demethylase 4A protein binding Molecular function 16415788 E2F7 144455 E2F transcription factor 7 negative regulation of transcription involved in G1/S transition of mitotic cell cycle Biological process 22802528 NIPBL 25836 Nipped-B homolog (Drosophila) uterus morphogenesis Biological process 19242925 CLOCK 9575 clock circadian regulator core promoter sequence-specific DNA binding Molecular function - WNT8A 7478 wingless-type MMTV integration site family, member 8A palate development Biological process 18413325 EIF2S3 1968 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa transmembrane transport Biological process - JAG1 182 jagged 1 pulmonary artery morphogenesis Biological process 9207787 SCG2 7857 secretogranin II negative regulation of extrinsic apoptotic signaling pathway Biological process 14970115 ZNF267 10308 zinc finger protein 267 transcription, DNA-templated Biological process - IKBKG 8517 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma ubiquitin ligase complex Cellular component 17314283 CEPT1 10390 choline/ethanolamine phosphotransferase 1 integral component of membrane Cellular component - NFKBIB 4793 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta toll-like receptor 10 signaling pathway Biological process - DSP 1832 desmoplakin scaffold protein binding Molecular function 10852826 IL1R1 3554 interleukin 1 receptor, type I cell surface Cellular component - SCX 642658 scleraxis basic helix-loop-helix transcription factor deltoid tuberosity development Biological process - ZNF16 7564 zinc finger protein 16 positive regulation of cell division Biological process - SYDE1 85360 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) GTPase activator activity Molecular function - CASQ2 845 calsequestrin 2 (cardiac muscle) intracellular Cellular component 16908766 DYRK2 8445 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 cellular response to DNA damage stimulus Biological process 19965871 EEF2 1938 eukaryotic translation elongation factor 2 protein binding Molecular function 19417104 TLX2 3196 T-cell leukemia homeobox 2 mesoderm formation Biological process - THAP3 90326 THAP domain containing, apoptosis associated protein 3 protein binding Molecular function 20200153 FOLH1 2346 folate hydrolase (prostate-specific membrane antigen) 1 metallopeptidase activity Molecular function - FAP 2191 fibroblast activation protein, alpha extracellular space Cellular component 17317851 LMBRD1 55788 LMBR1 domain containing 1 cobalamin metabolic process Biological process - FAM129B 64855 family with sequence similarity 129, member B negative regulation of apoptotic process Biological process 21148485 RPL5 6125 ribosomal protein L5 nucleolus Cellular component - ACTRT3 84517 actin-related protein T3 cytoskeleton Cellular component - WNT11 7481 wingless-type MMTV integration site family, member 11 bicellular tight junction assembly Biological process - ELF5 2001 E74-like factor 5 (ets domain transcription factor) positive regulation of transcription from RNA polymerase II promoter Biological process - HPS6 79803 Hermansky-Pudlak syndrome 6 membrane Cellular component 19946888 THSD7B 80731 thrombospondin, type I, domain containing 7B integral component of membrane Cellular component - TBL1Y 90665 transducin (beta)-like 1, Y-linked transcription regulatory region DNA binding Molecular function - ZFHX3 463 zinc finger homeobox 3 mitochondrion Cellular component - PPP1CA 5499 protein phosphatase 1, catalytic subunit, alpha isozyme regulation of translational initiation by eIF2 alpha dephosphorylation Biological process - PSMC6 5706 proteasome (prosome, macropain) 26S subunit, ATPase, 6 G1/S transition of mitotic cell cycle Biological process - ARFIP2 23647 ADP-ribosylation factor interacting protein 2 plasma membrane Cellular component 9312003 INPP5K 51763 inositol polyphosphate-5-phosphatase K cellular response to tumor necrosis factor Biological process 21712384 CYTIP 9595 cytohesin 1 interacting protein nucleoplasm Cellular component - DCK 1633 deoxycytidine kinase nucleus Cellular component - ADRA2A 150 adrenoceptor alpha 2A negative regulation of norepinephrine secretion Biological process 19477270 SLC37A2 219855 solute carrier family 37 (glucose-6-phosphate transporter), member 2 phosphate ion homeostasis Biological process - HOMEZ 57594 homeobox and leucine zipper encoding nucleolus Cellular component - KIF2B 84643 kinesin family member 2B regulation of chromosome segregation Biological process 19060894 THEG 51298 theg spermatid protein spermatogenesis Biological process - NR1D1 9572 nuclear receptor subfamily 1, group D, member 1 heme binding Molecular function 18006707 APOC1 341 apolipoprotein C-I phosphatidylcholine-sterol O-acyltransferase activator activity Molecular function 18992221 KMO 8564 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) cellular nitrogen compound metabolic process Biological process - LRP6 4040 low density lipoprotein receptor-related protein 6 protein homodimerization activity Molecular function 12897152 KRTAP9-2 83899 keratin associated protein 9-2 protein binding Molecular function 25416956 PDXK 8566 pyridoxal (pyridoxine, vitamin B6) kinase pyridoxal phosphate binding Molecular function 16600635 ZNF568 374900 zinc finger protein 568 nucleus Cellular component - TIPARP 25976 TCDD-inducible poly(ADP-ribose) polymerase multicellular organismal metabolic process Biological process - RPS14 6208 ribosomal protein S14 poly(A) RNA binding Molecular function 22681889 BSPH1 100131137 binder of sperm protein homolog 1 single fertilization Biological process - OTOP2 92736 otopetrin 2 integral component of membrane Cellular component - P2RX6 9127 purinergic receptor P2X, ligand gated ion channel, 6 transport Biological process 9242461 ATG5 9474 autophagy related 5 autophagosome assembly Biological process - SRY 6736 sex determining region Y male sex determination Biological process 1695712 LIMS1 3987 LIM and senescent cell antigen-like domains 1 positive regulation of cell-substrate adhesion Biological process 20926685 URB1 9875 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) biological_process Biological process - CHMP2A 27243 charged multivesicular body protein 2A establishment of protein localization Biological process 23045692 KLHL4 56062 kelch-like family member 4 cytoskeleton Cellular component - MAPK8 5599 mitogen-activated protein kinase 8 positive regulation of determination of dorsal identity Biological process - HK3 3101 hexokinase 3 (white cell) glucose transport Biological process - NRG2 9542 neuregulin 2 receptor binding Molecular function 9168114 CDC5L 988 cell division cycle 5-like DNA replication factor A complex Cellular component 24332808 IL1R1 3554 interleukin 1 receptor, type I platelet-derived growth factor receptor binding Molecular function 16477012 SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 positive regulation of interferon-gamma production Biological process - PANX1 24145 pannexin 1 innate immune response Biological process - SLU7 10569 SLU7 splicing factor homolog (S. cerevisiae) RNA splicing, via transesterification reactions Biological process 10197984 MAPK9 5601 mitogen-activated protein kinase 9 rhythmic process Biological process - DEPTOR 64798 DEP domain containing MTOR-interacting protein negative regulation of TOR signaling Biological process 19446321 RAMP2 10266 receptor (G protein-coupled) activity modifying protein 2 positive regulation of gene expression Biological process 18097473 MRPL44 65080 mitochondrial ribosomal protein L44 poly(A) RNA binding Molecular function 22681889 SP140 11262 SP140 nuclear body protein nuclear envelope Cellular component 8695863 PTGIS 5740 prostaglandin I2 (prostacyclin) synthase cellular response to hypoxia Biological process 21296955 GUK1 2987 guanylate kinase 1 nucleobase-containing small molecule interconversion Biological process - ADAM20 8748 ADAM metallopeptidase domain 20 metalloendopeptidase activity Molecular function - ANO6 196527 anoctamin 6 positive regulation of phagocytosis, engulfment Biological process - PLA2R1 22925 phospholipase A2 receptor 1, 180kDa receptor activity Molecular function 7721806 GOLPH3L 55204 golgi phosphoprotein 3-like trans-Golgi network membrane Cellular component 23345592 PIK3CG 5294 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma blood coagulation Biological process - CRP 1401 C-reactive protein, pentraxin-related inflammatory response Biological process 10408362 TCAP 8557 titin-cap FATZ binding Molecular function 15582318 EPHB1 2047 EPH receptor B1 positive regulation of synapse assembly Biological process - TARS 6897 threonyl-tRNA synthetase extracellular exosome Cellular component 20458337 ARID5B 84159 AT rich interactive domain 5B (MRF1-like) muscle organ morphogenesis Biological process - PSD4 23550 pleckstrin and Sec7 domain containing 4 vesicle-mediated transport Biological process - ADAR 103 adenosine deaminase, RNA-specific negative regulation of apoptotic process Biological process - PTPN4 5775 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) cytoplasm Cellular component 10940933 APOBEC3G 60489 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G cytidine deaminase activity Molecular function 17121840 TRAF6 7189 TNF receptor-associated factor 6, E3 ubiquitin protein ligase protein K63-linked ubiquitination Biological process 17135271 E2F3 1871 E2F transcription factor 3 core promoter binding Molecular function 15735762 STRC 161497 stereocilin stereocilium Cellular component - SPTAN1 6709 spectrin, alpha, non-erythrocytic 1 programmed cell death Biological process - GK 2710 glycerol kinase protein binding Molecular function 21988832 CDO1 1036 cysteine dioxygenase type 1 ferrous iron binding Molecular function - SALL4 57167 spalt-like transcription factor 4 heterochromatin Cellular component - GDI1 2664 GDP dissociation inhibitor 1 protein binding Molecular function 11809807 PREB 10113 prolactin regulatory element binding membrane organization Biological process - ATP1A2 477 ATPase, Na+/K+ transporting, alpha 2 polypeptide caveola Cellular component - DLG4 1742 discs, large homolog 4 (Drosophila) protein phosphatase binding Molecular function - MMP25 64386 matrix metallopeptidase 25 inflammatory response Biological process 10628838 DHX16 8449 DEAH (Asp-Glu-Ala-His) box polypeptide 16 RNA splicing Biological process - RND2 8153 Rho family GTPase 2 small GTPase mediated signal transduction Biological process - PARK7 11315 parkinson protein 7 mitochondrion Cellular component 21785459 ITGB1 3688 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) integrin alpha2-beta1 complex Cellular component 24823363 KCNIP3 30818 Kv channel interacting protein 3, calsenilin signal transduction Biological process 10900016 BANF1 8815 barrier to autointegration factor 1 cytosol Cellular component - FLOT1 10211 flotillin 1 cytoplasmic vesicle Cellular component 23983584 NCKAP1L 3071 NCK-associated protein 1-like positive regulation of CD4-positive, alpha-beta T cell differentiation Biological process - MAN1A1 4121 mannosidase, alpha, class 1A, member 1 calcium ion binding Molecular function - ACTB 60 actin, beta focal adhesion Cellular component 21423176 FGFR1OP 11116 FGFR1 oncogene partner protein tyrosine kinase inhibitor activity Molecular function 17888034 GPR78 27201 G protein-coupled receptor 78 adenylate cyclase-activating G-protein coupled receptor signaling pathway Biological process 17363172 FDXR 2232 ferredoxin reductase oxidation-reduction process Biological process - NLRC5 84166 NLR family, CARD domain containing 5 negative regulation of NF-kappaB transcription factor activity Biological process 20434986 DACT3 147906 dishevelled-binding antagonist of beta-catenin 3 negative regulation of canonical Wnt signaling pathway Biological process - VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor RNA polymerase II transcription factor complex Cellular component 17426122 LRR1 122769 leucine rich repeat protein 1 protein ubiquitination Biological process - WNT3A 89780 wingless-type MMTV integration site family, member 3A negative regulation of heart induction by canonical Wnt signaling pathway Biological process 19736317 DMTN 2039 dematin actin binding protein regulation of lamellipodium assembly Biological process 10565303 OR5D16 390144 olfactory receptor, family 5, subfamily D, member 16 G-protein coupled receptor activity Molecular function - LAMA2 3908 laminin, alpha 2 regulation of cell adhesion Biological process - TIPARP 25976 TCDD-inducible poly(ADP-ribose) polymerase nitrogen compound metabolic process Biological process - ACSS3 79611 acyl-CoA synthetase short-chain family member 3 metabolic process Biological process - PPM1G 5496 protein phosphatase, Mg2+/Mn2+ dependent, 1G cytoplasm Cellular component - TP53 7157 tumor protein p53 negative regulation of helicase activity Biological process 7663514 RPA1 6117 replication protein A1, 70kDa post-translational protein modification Biological process - SOX9 6662 SRY (sex determining region Y)-box 9 oligodendrocyte differentiation Biological process - TRAP1 10131 TNF receptor-associated protein 1 lipid particle Cellular component - TRIM32 22954 tripartite motif containing 32 translation initiation factor binding Molecular function - SOX8 30812 SRY (sex determining region Y)-box 8 negative regulation of photoreceptor cell differentiation Biological process - CLPB 81570 ClpB homolog, mitochondrial AAA ATPase chaperonin cellular_component Cellular component - ZFPM1 161882 zinc finger protein, FOG family member 1 platelet formation Biological process 11675338 DEFB119 245932 defensin, beta 119 cell surface Cellular component - ZDHHC13 54503 zinc finger, DHHC-type containing 13 endoplasmic reticulum Cellular component 16647879 CYP17A1 1586 cytochrome P450, family 17, subfamily A, polypeptide 1 response to insecticide Biological process - MPHOSPH8 54737 M-phase phosphoprotein 8 extracellular exosome Cellular component 23376485 DPPA2 151871 developmental pluripotency associated 2 chromatin binding Molecular function - FRAT2 23401 frequently rearranged in advanced T-cell lymphomas 2 multicellular organismal development Biological process 9635432 SYT17 51760 synaptotagmin XVII positive regulation of dendrite extension Biological process 23999003 BLOC1S3 388552 biogenesis of lysosomal organelles complex-1, subunit 3 protein binding Molecular function 15102850 HORMAD1 84072 HORMA domain containing 1 meiotic sister chromatid cohesion Biological process - TAF6 6878 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa protein heterodimerization activity Molecular function - CLN8 2055 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) neuromuscular process controlling posture Biological process - SP140L 93349 SP140 nuclear body protein-like chromatin binding Molecular function - SFRP5 6425 secreted frizzled-related protein 5 integral component of membrane Cellular component - ATG4C 84938 autophagy related 4C, cysteine peptidase cytosol Cellular component 12446702 PPP1R18 170954 protein phosphatase 1, regulatory subunit 18 actin binding Molecular function - PDIA2 64714 protein disulfide isomerase family A, member 2 protein folding in endoplasmic reticulum Biological process 22013210 CCL21 6366 chemokine (C-C motif) ligand 21 activation of GTPase activity Biological process 15778365 DGCR8 54487 DGCR8 microprocessor complex subunit nucleus Cellular component 15574589 PARP10 84875 poly (ADP-ribose) polymerase family, member 10 negative regulation of gene expression Biological process 23575687 AIP 9049 aryl hydrocarbon receptor interacting protein regulation of nucleic acid-templated transcription Biological process 9447995 ATP10D 57205 ATPase, class V, type 10D ion transmembrane transport Biological process - FOXP2 93986 forkhead box P2 metal ion binding Molecular function - HERPUD1 9709 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 protein binding Molecular function 18307982 FOXN1 8456 forkhead box N1 transcription from RNA polymerase II promoter Biological process 10767081 OLFM3 118427 olfactomedin 3 cell junction Cellular component - GGPS1 9453 geranylgeranyl diphosphate synthase 1 geranylgeranyl diphosphate biosynthetic process Biological process - APOM 55937 apolipoprotein M reverse cholesterol transport Biological process 15793583 POLR3G 10622 polymerase (RNA) III (DNA directed) polypeptide G (32kD) nuclear chromatin Cellular component 24107381 CASP2 835 caspase 2, apoptosis-related cysteine peptidase regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process - ZNF20 7568 zinc finger protein 20 regulation of transcription, DNA-templated Biological process - SLC35B2 347734 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 Golgi membrane Cellular component - POLR3H 171568 polymerase (RNA) III (DNA directed) polypeptide H (22.9kD) innate immune response Biological process - SRGAP2 23380 SLIT-ROBO Rho GTPase activating protein 2 negative regulation of neuron migration Biological process 22559944 RPL8 6132 ribosomal protein L8 viral transcription Biological process - Mar-01 64757 mitochondrial amidoxime reducing component 1 mitochondrial inner membrane Cellular component - CALR 811 calreticulin negative regulation of intracellular steroid hormone receptor signaling pathway Biological process 8107809 YY1 7528 YY1 transcription factor transcription corepressor activity Molecular function 1655281 JAG2 3714 jagged 2 morphogenesis of embryonic epithelium Biological process - ADAM19 8728 ADAM metallopeptidase domain 19 membrane protein ectodomain proteolysis Biological process - WNT8B 7479 wingless-type MMTV integration site family, member 8B positive regulation of canonical Wnt signaling pathway Biological process - MAP1LC3C 440738 microtubule-associated protein 1 light chain 3 gamma mitochondrion degradation Biological process - ABCB5 340273 ATP-binding cassette, sub-family B (MDR/TAP), member 5 metabolic process Biological process - SSR1 6745 signal sequence receptor, alpha endoplasmic reticulum membrane Cellular component - SELE 6401 selectin E response to lipopolysaccharide Biological process 18029551 CLIC4 25932 chloride intracellular channel 4 nuclear matrix Cellular component 14569596 SMAD7 4092 SMAD family member 7 intracellular signal transduction Biological process - TFDP3 51270 transcription factor Dp family, member 3 protein heterodimerization activity Molecular function 17062573 SMAD9 4093 SMAD family member 9 cytosol Cellular component - ARHGEF4 50649 Rho guanine nucleotide exchange factor (GEF) 4 small GTPase mediated signal transduction Biological process - TBX6 6911 T-box 6 somite rostral/caudal axis specification Biological process - S100A8 6279 S100 calcium binding protein A8 extracellular space Cellular component 16502470 GRB2 2885 growth factor receptor-bound protein 2 plasma membrane Cellular component - MAP4K4 9448 mitogen-activated protein kinase kinase kinase kinase 4 cytoplasm Cellular component 14966141 HCRTR2 3062 hypocretin (orexin) receptor 2 integral component of plasma membrane Cellular component 9491897 ADCY10 55811 adenylate cyclase 10 (soluble) magnesium ion binding Molecular function - OR51I2 390064 olfactory receptor, family 51, subfamily I, member 2 detection of chemical stimulus involved in sensory perception of smell Biological process 11121057 GPER1 2852 G protein-coupled estrogen receptor 1 intracellular Cellular component - GJA1 2697 gap junction protein, alpha 1, 43kDa endoplasmic reticulum membrane Cellular component - MARS2 92935 methionyl-tRNA synthetase 2, mitochondrial ATP binding Molecular function - NPM1 4869 nucleophosmin (nucleolar phosphoprotein B23, numatrin) positive regulation of translation Biological process 12882984 DGKA 1606 diacylglycerol kinase, alpha 80kDa ATP binding Molecular function - TLR2 7097 toll-like receptor 2 nitric oxide metabolic process Biological process - CDSN 1041 corneodesmosin skin morphogenesis Biological process 20691404 PAK4 10298 p21 protein (Cdc42/Rac)-activated kinase 4 protein serine/threonine kinase activity Molecular function - ZNF558 148156 zinc finger protein 558 DNA binding Molecular function - BIRC8 112401 baculoviral IAP repeat containing 8 neuron apoptotic process Biological process - OR10AD1 121275 olfactory receptor, family 10, subfamily AD, member 1 plasma membrane Cellular component - HIRA 7290 histone cell cycle regulator nucleus Cellular component - MYO5B 4645 myosin VB Rab GTPase binding Molecular function 17462998 MISP 126353 mitotic spindle positioning cell division Biological process - PSMD3 5709 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - ZNF653 115950 zinc finger protein 653 DNA binding Molecular function - DST 667 dystonin nuclear envelope Cellular component - APOA1 335 apolipoprotein A-I positive regulation of Rho protein signal transduction Biological process 23726972 POR 5447 P450 (cytochrome) oxidoreductase enzyme binding Molecular function - CITED1 4435 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 response to interleukin-11 Biological process - ALG8 79053 ALG8, alpha-1,3-glucosyltransferase protein N-linked glycosylation Biological process 12480927 AKAP3 10566 A kinase (PRKA) anchor protein 3 nucleus Cellular component 21630459 OPCML 4978 opioid binding protein/cell adhesion molecule-like cell adhesion Biological process 7721093 RPS27A 6233 ribosomal protein S27a cytokine-mediated signaling pathway Biological process - VIL1 7429 villin 1 cellular response to epidermal growth factor stimulus Biological process 17229814 RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 protein heterooligomerization Biological process 22817896 PER2 8864 period circadian clock 2 transcription factor binding transcription factor activity Molecular function - CLOCK 9575 clock circadian regulator negative regulation of transcription, DNA-templated Biological process - PICK1 9463 protein interacting with PRKCA 1 Golgi apparatus Cellular component - HLA-DPB1 3115 major histocompatibility complex, class II, DP beta 1 membrane Cellular component 19946888 CASP3 836 caspase 3, apoptosis-related cysteine peptidase plasma membrane Cellular component - HFE 3077 hemochromatosis negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process Biological process 24904118 USP13 8975 ubiquitin specific peptidase 13 (isopeptidase T-3) ubiquitin protein ligase binding Molecular function 21659512 MMP9 4318 matrix metallopeptidase 9 ossification Biological process - SOAT2 8435 sterol O-acyltransferase 2 brush border Cellular component 14615411 GPI 2821 glucose-6-phosphate isomerase humoral immune response Biological process 3020690 ADIG 149685 adipogenin nucleus Cellular component 15567149 SNRNP200 23020 small nuclear ribonucleoprotein 200kDa (U5) ATP-dependent helicase activity Molecular function 9539711 PFDN5 5204 prefoldin subunit 5 regulation of transcription, DNA-templated Biological process 9792694 HIST1H2BF 8343 histone cluster 1, H2bf antibacterial humoral response Biological process 12860195 CHAD 1101 chondroadherin bone development Biological process - WDR4 10785 WD repeat domain 4 nucleoplasm Cellular component - DVL1 1855 dishevelled segment polarity protein 1 cytoplasm Cellular component - ANAPC1 64682 anaphase promoting complex subunit 1 protein K11-linked ubiquitination Biological process 18485873 SLPI 6590 secretory leukocyte peptidase inhibitor extracellular matrix Cellular component 20551380 PIK3R6 146850 phosphoinositide-3-kinase, regulatory subunit 6 blood coagulation Biological process - PLAC9 219348 placenta-specific 9 protein binding Molecular function 25416956 ARX 170302 aristaless related homeobox cerebral cortex GABAergic interneuron migration Biological process - PES1 23481 pescadillo ribosomal biogenesis factor 1 nucleoplasm Cellular component 16738141 TRPC3 7222 transient receptor potential cation channel, subfamily C, member 3 ion transmembrane transport Biological process - RPL27A 6157 ribosomal protein L27a translational termination Biological process - WWP2 11060 WW domain containing E3 ubiquitin protein ligase 2 negative regulation of transporter activity Biological process 18776082 STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) eating behavior Biological process - DNASE1L3 1776 deoxyribonuclease I-like 3 endodeoxyribonuclease activity, producing 5'-phosphomonoesters Molecular function - ASIC1 41 acid sensing (proton gated) ion channel 1 calcium ion transmembrane transport Biological process - P2RX7 5027 purinergic receptor P2X, ligand gated ion channel, 7 regulation of killing of cells of other organism Biological process 17785580 PPARD 5467 peroxisome proliferator-activated receptor delta wound healing Biological process - PDE6H 5149 phosphodiesterase 6H, cGMP-specific, cone, gamma enzyme inhibitor activity Molecular function 8786098 GZMM 3004 granzyme M (lymphocyte met-ase 1) apoptotic process Biological process - PFKL 5211 phosphofructokinase, liver 6-phosphofructokinase complex Cellular component 6444532 ERCC2 2068 excision repair cross-complementation group 2 response to hypoxia Biological process - CRYBG3 131544 beta-gamma crystallin domain containing 3 carbohydrate binding Molecular function - DAXX 1616 death-domain associated protein PML body Cellular component 15247905 DDIT3 1649 DNA-damage-inducible transcript 3 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 22065586 DGKD 8527 diacylglycerol kinase, delta 130kDa protein homooligomerization Biological process 12200442 UNC93B1 81622 unc-93 homolog B1 (C. elegans) toll-like receptor 9 signaling pathway Biological process 19006693 IFNA2 3440 interferon, alpha 2 positive regulation of peptidyl-serine phosphorylation of STAT protein Biological process - ABHD11 83451 abhydrolase domain containing 11 cellular_component Cellular component - RAB37 326624 RAB37, member RAS oncogene family regulation of exocytosis Biological process - PTPN1 5770 protein tyrosine phosphatase, non-receptor type 1 enzyme binding Molecular function 22169477 LOC400927-CSNK1E 102800317 LOC400927-CSNK1E readthrough regulation of cell shape Biological process - CXADR 1525 coxsackie virus and adenovirus receptor integral component of plasma membrane Cellular component 9096397 UBR4 23352 ubiquitin protein ligase E3 component n-recognin 4 viral process Biological process - MTMR4 9110 myotubularin related protein 4 protein dephosphorylation Biological process 9736772 CABLES1 91768 Cdk5 and Abl enzyme substrate 1 nucleus Cellular component - CDKN1B 1027 cyclin-dependent kinase inhibitor 1B (p27, Kip1) positive regulation of microtubule polymerization Biological process - GH2 2689 growth hormone 2 extracellular region Cellular component - ADRBK1 156 adrenergic, beta, receptor kinase 1 ATP binding Molecular function - CXCR2 3579 chemokine (C-X-C motif) receptor 2 chemotaxis Biological process 10725748 DERL1 79139 derlin 1 positive regulation of protein ubiquitination Biological process 24089527 FANCI 55215 Fanconi anemia, complementation group I positive regulation of protein ubiquitination Biological process 18029348 ZSCAN30 100101467 zinc finger and SCAN domain containing 30 regulation of transcription, DNA-templated Biological process - CRY2 1408 cryptochrome circadian clock 2 glucose homeostasis Biological process - SMG1 23049 SMG1 phosphatidylinositol 3-kinase-related kinase protein binding Molecular function 11544179 CASP6 839 caspase 6, apoptosis-related cysteine peptidase proteolysis Biological process 12888622 TAF1B 9014 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa termination of RNA polymerase I transcription Biological process - MXI1 4601 MAX interactor 1, dimerization protein nucleolus Cellular component - DDX3X 1654 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked protein binding Molecular function 10074132 BCL2L1 598 BCL2-like 1 apoptotic process in bone marrow Biological process - VNN3 55350 vanin 3 biological_process Biological process - MAPRE2 10982 microtubule-associated protein, RP/EB family, member 2 cell proliferation Biological process 9233623 CEP162 22832 centrosomal protein 162kDa nucleoplasm Cellular component - PRKD1 5587 protein kinase D1 positive regulation of peptidyl-serine phosphorylation Biological process 20497126 MOS 4342 v-mos Moloney murine sarcoma viral oncogene homolog activation of MAPKK activity Biological process - WNT1 7471 wingless-type MMTV integration site family, member 1 midbrain development Biological process - MAPT 4137 microtubule-associated protein tau regulation of microtubule-based movement Biological process - NCAM1 4684 neural cell adhesion molecule 1 integral component of membrane Cellular component - UTRN 7402 utrophin plasma membrane Cellular component - WNT1 7471 wingless-type MMTV integration site family, member 1 ubiquitin-dependent SMAD protein catabolic process Biological process - SIK1 150094 salt-inducible kinase 1 nucleus Cellular component 16306228 CCIN 881 calicin nucleus Cellular component 21630459 NLRP12 91662 NLR family, pyrin domain containing 12 negative regulation of cytokine secretion Biological process 16203735 ROS1 6098 ROS proto-oncogene 1 , receptor tyrosine kinase spermatogenesis Biological process - ZCCHC4 29063 zinc finger, CCHC domain containing 4 methylation Biological process - PRKD1 5587 protein kinase D1 regulation of keratinocyte proliferation Biological process - TLX1 3195 T-cell leukemia homeobox 1 cell fate commitment Biological process - FXYD1 5348 FXYD domain containing ion transport regulator 1 transmembrane transport Biological process - KCTD3 51133 potassium channel tetramerization domain containing 3 protein homooligomerization Biological process - PRDX2 7001 peroxiredoxin 2 negative regulation of neuron apoptotic process Biological process - UMPS 7372 uridine monophosphate synthetase orotate phosphoribosyltransferase activity Molecular function - TAF1 6872 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa protein serine/threonine kinase activity Molecular function 15053879 RABEP1 9135 rabaptin, RAB GTPase binding effector protein 1 apoptotic process Biological process - EGFR 1956 epidermal growth factor receptor salivary gland morphogenesis Biological process - ZP3 7784 zona pellucida glycoprotein 3 (sperm receptor) positive regulation of type IV hypersensitivity Biological process - DHX38 9785 DEAH (Asp-Glu-Ala-His) box polypeptide 38 mRNA 3'-end processing Biological process - CASC5 57082 cancer susceptibility candidate 5 nucleosome assembly Biological process - Mar-01 64757 mitochondrial amidoxime reducing component 1 nitrate reductase activity Molecular function 20861021 ATRN 8455 attractin pigmentation Biological process - CASP7 840 caspase 7, apoptosis-related cysteine peptidase nucleoplasm Cellular component - NPPB 4879 natriuretic peptide B receptor binding Molecular function 12727915 CTNNA3 29119 catenin (cadherin-associated protein), alpha 3 cytoplasm Cellular component - PSIP1 11168 PC4 and SFRS1 interacting protein 1 transcription, DNA-templated Biological process - FH 2271 fumarate hydratase extracellular exosome Cellular component 20458337 LYN 4067 LYN proto-oncogene, Src family tyrosine kinase ubiquitin protein ligase binding Molecular function - S100A13 6284 S100 calcium binding protein A13 cytosol Cellular component 12746488 PLAT 5327 plasminogen activator, tissue platelet-derived growth factor receptor signaling pathway Biological process - SHANK2 22941 SH3 and multiple ankyrin repeat domains 2 photoreceptor outer segment Cellular component - SIRT1 23411 sirtuin 1 positive regulation of macrophage apoptotic process Biological process - CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa actin filament binding Molecular function - WDR3 10885 WD repeat domain 3 nucleus Cellular component - TXNRD1 7296 thioredoxin reductase 1 mesoderm formation Biological process - ERCC8 1161 excision repair cross-complementation group 8 protein complex binding Molecular function 16916636 BGN 633 biglycan peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan Biological process - ODF2 4957 outer dense fiber of sperm tails 2 protein binding Molecular function 16980960 CD81 975 CD81 molecule receptor-mediated virion attachment to host cell Biological process 14676841 BDNF 627 brain-derived neurotrophic factor cytoplasm Cellular component - TMEM35 59353 transmembrane protein 35 peroxisomal membrane Cellular component - PSMC2 5701 proteasome (prosome, macropain) 26S subunit, ATPase, 2 protein polyubiquitination Biological process - CUBN 8029 cubilin (intrinsic factor-cobalamin receptor) cobalamin metabolic process Biological process - JPH4 84502 junctophilin 4 calcium ion transport into cytosol Biological process 19095005 PLCH1 23007 phospholipase C, eta 1 calcium-dependent phospholipase C activity Molecular function 15702972 MALT1 10892 MALT1 paracaspase activation of NF-kappaB-inducing kinase activity Biological process 15125833 DLL4 54567 delta-like 4 (Drosophila) integral component of membrane Cellular component - EMG1 10436 EMG1 N1-specific pseudouridine methyltransferase poly(A) RNA binding Molecular function 22658674 TBXA2R 6915 thromboxane A2 receptor positive regulation of GTPase activity Biological process - HPR 3250 haptoglobin-related protein hemoglobin binding Molecular function 2987228 NCOA1 8648 nuclear receptor coactivator 1 ligand-dependent nuclear receptor binding Molecular function 17363140 DUSP3 1845 dual specificity phosphatase 3 toll-like receptor TLR1:TLR2 signaling pathway Biological process - CREB1 1385 cAMP responsive element binding protein 1 circadian rhythm Biological process - EMG1 10436 EMG1 N1-specific pseudouridine methyltransferase cytoplasm Cellular component - CIT 11113 citron rho-interacting serine/threonine kinase generation of neurons Biological process 11086988 REEP2 51308 receptor accessory protein 2 regulation of intracellular transport Biological process - HIF3A 64344 hypoxia inducible factor 3, alpha subunit mitochondrion Cellular component - ENO1 2023 enolase 1, (alpha) carbohydrate metabolic process Biological process - ACP2 53 acid phosphatase 2, lysosomal integral component of membrane Cellular component - ZBED4 9889 zinc finger, BED-type containing 4 cytoplasm Cellular component 19369242 FAM63A 55793 family with sequence similarity 63, member A extracellular exosome Cellular component 23376485 DBN1 1627 drebrin 1 regulation of neuronal synaptic plasticity Biological process 12009525 INSM1 3642 insulinoma-associated 1 regulation of protein complex assembly Biological process 19124461 DCAF13 25879 DDB1 and CUL4 associated factor 13 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Biological process - STOX2 56977 storkhead box 2 cellular_component Cellular component - ARSB 411 arylsulfatase B glycosphingolipid metabolic process Biological process - GRM8 2918 glutamate receptor, metabotropic 8 visual perception Biological process 9473604 RBCK1 10616 RanBP-type and C3HC4-type zinc finger containing 1 negative regulation of necroptotic process Biological process - PXK 54899 PX domain containing serine/threonine kinase microtubule organizing center Cellular component - PFKFB2 5208 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 fructose-2,6-bisphosphate 2-phosphatase activity Molecular function - ARID5B 84159 AT rich interactive domain 5B (MRF1-like) female gonad development Biological process - RAB27A 5873 RAB27A, member RAS oncogene family positive regulation of gene expression Biological process 23092844 TRIM48 79097 tripartite motif containing 48 zinc ion binding Molecular function - ERCC2 2068 excision repair cross-complementation group 2 transcription from RNA polymerase I promoter Biological process - TCP10L 140290 t-complex 10-like negative regulation of transcription from RNA polymerase II promoter Biological process 14586771 NR1H4 9971 nuclear receptor subfamily 1, group H, member 4 chenodeoxycholic acid binding Molecular function 10334992 REST 5978 RE1-silencing transcription factor negative regulation of insulin secretion Biological process 20942606 ESPN 83715 espin SH3 domain binding Molecular function 12598619 CALR 811 calreticulin protein maturation by protein folding Biological process 17563366 OSBPL5 114879 oxysterol binding protein-like 5 oxysterol binding Molecular function 10588946 SNRPA1 6627 small nuclear ribonucleoprotein polypeptide A' poly(A) RNA binding Molecular function 22681889 CPNE3 8895 copine III calcium-dependent phospholipid binding Molecular function 11041869 NOTCH2 4853 notch 2 inflammatory response to antigenic stimulus Biological process - B3GAT1 27087 beta-1,3-glucuronyltransferase 1 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity Molecular function - RBP4 5950 retinol binding protein 4, plasma eye development Biological process - GEM 2669 GTP binding protein overexpressed in skeletal muscle small GTPase mediated signal transduction Biological process - GLIPR2 152007 GLI pathogenesis-related 2 positive regulation of epithelial to mesenchymal transition Biological process 23516513 SPAG8 26206 sperm associated antigen 8 biological_process Biological process - FKBP1B 2281 FK506 binding protein 1B, 12.6 kDa regulation of ryanodine-sensitive calcium-release channel activity Biological process 7592869 AGO4 192670 argonaute RISC catalytic component 4 fibroblast growth factor receptor signaling pathway Biological process - ELL3 80237 elongation factor RNA polymerase II-like 3 positive regulation of neural precursor cell proliferation Biological process - RAB30 27314 RAB30, member RAS oncogene family cytoplasm Cellular component - SLC25A16 8034 solute carrier family 25 (mitochondrial carrier), member 16 transmembrane transport Biological process - EGLN2 112398 egl-9 family hypoxia-inducible factor 2 L-ascorbic acid binding Molecular function - ASPN 54829 asporin proteinaceous extracellular matrix Cellular component 17827158 ITGB1BP1 9270 integrin beta 1 binding protein 1 ruffle Cellular component 11919189 DDO 8528 D-aspartate oxidase cofactor binding Molecular function 20603179 PINK1 65018 PTEN induced putative kinase 1 negative regulation of oxidative stress-induced neuron death Biological process 24522549 KIF2B 84643 kinesin family member 2B microtubule binding Molecular function - SOX13 9580 SRY (sex determining region Y)-box 13 anatomical structure morphogenesis Biological process 10198172 COL1A2 1278 collagen, type I, alpha 2 collagen catabolic process Biological process - PIF1 80119 PIF1 5'-to-3' DNA helicase regulation of telomere maintenance Biological process 16522649 STAMBP 10617 STAM binding protein plasma membrane Cellular component - NPFF 8620 neuropeptide FF-amide peptide precursor cytosol Cellular component - HEY1 23462 hes-related family bHLH transcription factor with YRPW motif 1 protein dimerization activity Molecular function - RPL35 11224 ribosomal protein L35 translational initiation Biological process - ZNF367 195828 zinc finger protein 367 nucleus Cellular component 15344908 SMAD2 4087 SMAD family member 2 I-SMAD binding Molecular function 9256479 TWF1 5756 twinfilin actin-binding protein 1 focal adhesion Cellular component 21423176 GGT7 2686 gamma-glutamyltransferase 7 glutathione hydrolase activity Molecular function - PARP10 84875 poly (ADP-ribose) polymerase family, member 10 negative regulation of fibroblast proliferation Biological process 15674325 PAX3 5077 paired box 3 positive regulation of transcription from RNA polymerase II promoter Biological process 11863357 GM2A 2760 GM2 ganglioside activator extracellular exosome Cellular component 19056867 NEUROD1 4760 neuronal differentiation 1 nucleocytoplasmic transport Biological process - CHRNB2 1141 cholinergic receptor, nicotinic, beta 2 (neuronal) calcium ion transport Biological process - SOX9 6662 SRY (sex determining region Y)-box 9 regulation of cell proliferation Biological process - TRIM32 22954 tripartite motif containing 32 cytosol Cellular component - TRIM24 8805 tripartite motif containing 24 regulation of signal transduction by p53 class mediator Biological process - EHD1 10938 EH-domain containing 1 positive regulation of myoblast fusion Biological process - MMP9 4318 matrix metallopeptidase 9 negative regulation of intrinsic apoptotic signaling pathway Biological process 22984561 IPO5 3843 importin 5 ribosomal protein import into nucleus Biological process 9687515 ADRM1 11047 adhesion regulating molecule 1 cytoplasm Cellular component - TC2N 123036 tandem C2 domains, nuclear calcium-dependent phospholipid binding Molecular function - RNPS1 10921 RNA binding protein S1, serine-rich domain regulation of alternative mRNA splicing, via spliceosome Biological process 22203037 NME6 10201 NME/NM23 nucleoside diphosphate kinase 6 GTP biosynthetic process Biological process - AREG 374 amphiregulin glial cell proliferation Biological process - PER3 8863 period circadian clock 3 circadian regulation of gene expression Biological process - VEGFC 7424 vascular endothelial growth factor C vascular endothelial growth factor receptor signaling pathway Biological process - SMC3 9126 structural maintenance of chromosomes 3 mediator complex binding Molecular function - GPN2 54707 GPN-loop GTPase 2 metabolic process Biological process - EPB41L3 23136 erythrocyte membrane protein band 4.1-like 3 paranodal junction assembly Biological process - BRSK2 9024 BR serine/threonine kinase 2 ATP binding Molecular function 14976552 NRP1 8829 neuropilin 1 coronary artery morphogenesis Biological process - INHBB 3625 inhibin, beta B cell differentiation Biological process 10320815 TADA3 10474 transcriptional adaptor 3 STAGA complex Cellular component 11564863 IGLC3 3539 immunoglobulin lambda constant 3 (Kern-Oz+ marker) antigen binding Molecular function - RAB40AL 282808 RAB40A, member RAS oncogene family-like intracellular protein transport Biological process - CHEK2 11200 checkpoint kinase 2 double-strand break repair Biological process 18317453 RBMY1J 378951 RNA binding motif protein, Y-linked, family 1, member J RNA splicing Biological process - ITPRIPL1 150771 inositol 1,4,5-trisphosphate receptor interacting protein-like 1 integral component of membrane Cellular component - DPEP1 1800 dipeptidase 1 (renal) homocysteine metabolic process Biological process 20031578 PPAP2A 8611 phosphatidic acid phosphatase type 2A regulation of lipid metabolic process Biological process 9468526 MARVELD2 153562 MARVEL domain containing 2 basolateral plasma membrane Cellular component 23073616 SNF8 11267 SNF8, ESCRT-II complex subunit protein homodimerization activity Molecular function 14505570 ING5 84289 inhibitor of growth family, member 5 histone H3 acetylation Biological process 16387653 DAZL 1618 deleted in azoospermia-like cytoplasm Cellular component - NRG2 9542 neuregulin 2 innate immune response Biological process - PCDHA7 56141 protocadherin alpha 7 cell adhesion Biological process 10380929 WNT4 54361 wingless-type MMTV integration site family, member 4 non-canonical Wnt signaling pathway via MAPK cascade Biological process 17720811 TEAD3 7005 TEA domain family member 3 gene expression Biological process - TFAP2A 7020 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) face morphogenesis Biological process - VDAC3 7419 voltage-dependent anion channel 3 porin activity Molecular function - NDRG4 65009 NDRG family member 4 endoplasmic reticulum membrane Cellular component - MUC16 94025 mucin 16, cell surface associated post-translational protein modification Biological process - CD74 972 CD74 molecule, major histocompatibility complex, class II invariant chain identical protein binding Molecular function 12782713 HCN1 348980 hyperpolarization activated cyclic nucleotide gated potassium channel 1 potassium ion transport Biological process 9405696 GFRA1 2674 GDNF family receptor alpha 1 anchored component of membrane Cellular component - PCSK5 5125 proprotein convertase subtilisin/kexin type 5 nerve growth factor processing Biological process - VANGL1 81839 VANGL planar cell polarity protein 1 protein binding Molecular function 15205336 OR8J1 219477 olfactory receptor, family 8, subfamily J, member 1 plasma membrane Cellular component - SCUBE3 222663 signal peptide, CUB domain, EGF-like 3 protein homooligomerization Biological process 15234972 ALOX12 239 arachidonate 12-lipoxygenase reactive oxygen species metabolic process Biological process 12858336 MCU 90550 mitochondrial calcium uniporter glucose homeostasis Biological process 22829870 OR1A1 8383 olfactory receptor, family 1, subfamily A, member 1 G-protein coupled receptor activity Molecular function - WBSCR27 155368 Williams Beuren syndrome chromosome region 27 protein binding Molecular function 25814554 ALPK3 57538 alpha-kinase 3 heart development Biological process - ZNF592 9640 zinc finger protein 592 nucleoplasm Cellular component - KCNAB3 9196 potassium channel, voltage gated subfamily A regulatory beta subunit 3 potassium channel regulator activity Molecular function 9857044 ZFP62 643836 ZFP62 zinc finger protein metal ion binding Molecular function - USP14 9097 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) regulation of chemotaxis Biological process 19106094 MUC3A 4584 mucin 3A, cell surface associated protein O-linked glycosylation Biological process - SLC17A7 57030 solute carrier family 17 (vesicular glutamate transporter), member 7 excitatory synapse Cellular component - SEC24D 9871 SEC24 family member D intracellular protein transport Biological process - CLTB 1212 clathrin, light chain B cytoplasm Cellular component - ANXA7 310 annexin A7 nuclear envelope Cellular component - CEPT1 10390 choline/ethanolamine phosphotransferase 1 CDP-choline pathway Biological process - AURKA 6790 aurora kinase A spindle stabilization Biological process 21820309 TMEM173 340061 transmembrane protein 173 innate immune response Biological process - ITGAM 3684 integrin, alpha M (complement component 3 receptor 3 subunit) heparin binding Molecular function - STAR 6770 steroidogenic acute regulatory protein response to corticosterone Biological process - RBSN 64145 rabenosyn, RAB effector extracellular exosome Cellular component 18570454 LRP2 4036 low density lipoprotein receptor-related protein 2 endosome Cellular component - C5 727 complement component 5 complement activation, alternative pathway Biological process - OR52R1 119695 olfactory receptor, family 52, subfamily R, member 1 (gene/pseudogene) G-protein coupled receptor signaling pathway Biological process - MAFG 4097 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G regulation of cellular pH Biological process - TLR3 7098 toll-like receptor 3 response to exogenous dsRNA Biological process 21266579 RAP2C 57826 RAP2C, member of RAS oncogene family negative regulation of cell migration Biological process - C1D 10438 C1D nuclear receptor corepressor ligand-dependent nuclear receptor binding Molecular function - SRSF7 6432 serine/arginine-rich splicing factor 7 poly(A) RNA binding Molecular function 22658674 ARNT 405 aryl hydrocarbon receptor nuclear translocator positive regulation of glycolytic process Biological process 8089148 GGCX 2677 gamma-glutamyl carboxylase cellular protein modification process Biological process 1749935 KLK4 9622 kallikrein-related peptidase 4 serine-type endopeptidase activity Molecular function - B3GNT6 192134 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 integral component of membrane Cellular component - IL16 3603 interleukin 16 extracellular space Cellular component - ICAM1 3383 intercellular adhesion molecule 1 focal adhesion Cellular component 21423176 MKLN1 4289 muskelin 1, intracellular mediator containing kelch motifs regulation of cell shape Biological process - LDHD 197257 lactate dehydrogenase D mitochondrion Cellular component - EMX1 2016 empty spiracles homeobox 1 in utero embryonic development Biological process - SPANXB1 728695 SPANX family, member B1 nucleus Cellular component 10906052 CT45A5 441521 cancer/testis antigen family 45, member A5 protein binding Molecular function 21516116 NIPBL 25836 Nipped-B homolog (Drosophila) outflow tract morphogenesis Biological process 19242925 RACGAP1 29127 Rac GTPase activating protein 1 cytosol Cellular component - APLP2 334 amyloid beta (A4) precursor-like protein 2 midbrain development Biological process - DEDD2 162989 death effector domain containing 2 protein binding Molecular function 11741985 MAP3K19 80122 mitogen-activated protein kinase kinase kinase 19 activation of MAPKK activity Biological process - GRIN3B 116444 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B regulation of calcium ion transport Biological process 11735224 ALG11 440138 ALG11, alpha-1,2-mannosyltransferase membrane Cellular component 19946888 GPC4 2239 glypican 4 proteinaceous extracellular matrix Cellular component - LIN7A 8825 lin-7 homolog A (C. elegans) basolateral plasma membrane Cellular component - HSD3B1 3283 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 glucocorticoid biosynthetic process Biological process - GUCA2B 2981 guanylate cyclase activator 2B (uroguanylin) calcium sensitive guanylate cyclase activator activity Molecular function 8605041 ZNF703 80139 zinc finger protein 703 positive regulation of cell proliferation Biological process 21328542 PDCD4 27250 programmed cell death 4 (neoplastic transformation inhibitor) cell aging Biological process 12054647 INSM1 3642 insulinoma-associated 1 sequence-specific DNA binding transcription factor activity Molecular function 11842116 FOLH1 2346 folate hydrolase (prostate-specific membrane antigen) 1 carboxypeptidase activity Molecular function - PHB 5245 prohibitin DNA biosynthetic process Biological process - CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 coumarin metabolic process Biological process - CLEC12A 160364 C-type lectin domain family 12, member A carbohydrate binding Molecular function - FAM200A 221786 family with sequence similarity 200, member A integral component of membrane Cellular component - SCAND1 51282 SCAN domain containing 1 regulation of transcription from RNA polymerase II promoter Biological process - UBE2A 7319 ubiquitin-conjugating enzyme E2A protein polyubiquitination Biological process - PSPHP1 8781 phosphoserine phosphatase pseudogene 1 dephosphorylation Biological process 9573387 PLEK 5341 pleckstrin cytoplasm Cellular component 8694752 COL7A1 1294 collagen, type VII, alpha 1 extracellular matrix Cellular component 22261194 RAB11A 8766 RAB11A, member RAS oncogene family renal water homeostasis Biological process - SRSF7 6432 serine/arginine-rich splicing factor 7 nucleoplasm Cellular component - CBX5 23468 chromobox homolog 5 blood coagulation Biological process - ACADVL 37 acyl-CoA dehydrogenase, very long chain mitochondrial nucleoid Cellular component 18063578 CTHRC1 115908 collagen triple helix repeat containing 1 collagen trimer Cellular component - DFFB 1677 DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) apoptotic DNA fragmentation Biological process - LPIN1 23175 lipin 1 phosphatidylethanolamine biosynthetic process Biological process - SPINK13 153218 serine peptidase inhibitor, Kazal type 13 (putative) negative regulation of acrosome reaction Biological process - APOE 348 apolipoprotein E response to insulin Biological process - MYF6 4618 myogenic factor 6 (herculin) positive regulation of myoblast differentiation Biological process - MTRR 4552 5-methyltetrahydrofolate-homocysteine methyltransferase reductase DNA methylation Biological process - CA3 761 carbonic anhydrase III response to ethanol Biological process - LIG3 3980 ligase III, DNA, ATP-dependent negative regulation of mitochondrial DNA replication Biological process 21878356 NEUROD6 63974 neuronal differentiation 6 protein dimerization activity Molecular function - ZNF749 388567 zinc finger protein 749 metal ion binding Molecular function - RFWD2 64326 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase Golgi membrane Cellular component - SEMA3D 223117 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D cell differentiation Biological process - MLST8 64223 MTOR associated protein, LST8 homolog (S. cerevisiae) vascular endothelial growth factor receptor signaling pathway Biological process - FGFR2 2263 fibroblast growth factor receptor 2 positive regulation of phospholipase activity Biological process 16844695 HNRNPH3 3189 heterogeneous nuclear ribonucleoprotein H3 (2H9) protein binding Molecular function 22720776 SPN 6693 sialophorin response to protozoan Biological process - ATP13A4 84239 ATPase type 13A4 integral component of membrane Cellular component - RRAGC 64121 Ras-related GTP binding C cell growth Biological process 11073942 TP63 8626 tumor protein p63 epidermal cell division Biological process - NPHP4 261734 nephronophthisis 4 photoreceptor cell maintenance Biological process - ZNF836 162962 zinc finger protein 836 nucleus Cellular component - BMPR2 659 bone morphogenetic protein receptor, type II (serine/threonine kinase) dendrite Cellular component - LEFTY1 10637 left-right determination factor 1 heart morphogenesis Biological process - CSTF3 1479 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa mRNA cleavage Biological process 7984242 AVP 551 arginine vasopressin positive regulation of cAMP biosynthetic process Biological process - AP2A1 160 adaptor-related protein complex 2, alpha 1 subunit endocytosis Biological process 12036598 FNTA 2339 farnesyltransferase, CAAX box, alpha acetylcholine receptor regulator activity Molecular function - FLT3 2322 fms-related tyrosine kinase 3 transmembrane receptor protein tyrosine kinase signaling pathway Biological process 7507245 DDX3X 1654 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 18846110 SERPINA5 5104 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 phosphatidylcholine binding Molecular function 9556620 HILS1 373861 histone linker H1 domain, spermatid-specific 1, pseudogene nucleosome assembly Biological process - MBD6 114785 methyl-CpG binding domain protein 6 chromatin binding Molecular function 20700456 SH3KBP1 30011 SH3-domain kinase binding protein 1 endocytosis Biological process - MYBBP1A 10514 MYB binding protein (P160) 1a regulation of transcription, DNA-templated Biological process 10644447 NPY5R 4889 neuropeptide Y receptor Y5 eating behavior Biological process - CLIP1 6249 CAP-GLY domain containing linker protein 1 microtubule bundle formation Biological process 17889670 HEBP2 23593 heme binding protein 2 protein binding Molecular function 16189514 CTSL 1514 cathepsin L proteolysis involved in cellular protein catabolic process Biological process 22952693 MFSD8 256471 major facilitator superfamily domain containing 8 lysosome organization Biological process - NOX4 50507 NADPH oxidase 4 cardiac muscle cell differentiation Biological process - PFKFB2 5208 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 fructose metabolic process Biological process - MARK1 4139 MAP/microtubule affinity-regulating kinase 1 magnesium ion binding Molecular function 14976552 EIF5A2 56648 eukaryotic translation initiation factor 5A2 peptidyl-lysine modification to peptidyl-hypusine Biological process - THEM4 117145 thioesterase superfamily member 4 mitochondrion Cellular component 19604401 HFE2 148738 hemochromatosis type 2 (juvenile) protein binding Molecular function 19357398 SLC35A5 55032 solute carrier family 35, member A5 nucleotide transmembrane transport Biological process - BAZ2A 11176 bromodomain adjacent to zinc finger domain, 2A RNA binding Molecular function - MRPS11 64963 mitochondrial ribosomal protein S11 mitochondrial small ribosomal subunit Cellular component - CLCA3P 9629 chloride channel accessory 3, pseudogene chloride channel activity Molecular function - PCNA 5111 proliferating cell nuclear antigen DNA strand elongation involved in DNA replication Biological process - PXMP4 11264 peroxisomal membrane protein 4, 24kDa peroxisome Cellular component - KMO 8564 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) NAD(P)H oxidase activity Molecular function 10672018 CFL1 1072 cofilin 1 (non-muscle) neural crest cell migration Biological process - CDC20 991 cell division cycle 20 mitotic spindle assembly checkpoint Biological process - FURIN 5045 furin (paired basic amino acid cleaving enzyme) post-translational protein modification Biological process - PRKCG 5582 protein kinase C, gamma regulation of response to food Biological process - GJA1 2697 gap junction protein, alpha 1, 43kDa transport Biological process 1696265 NUCB1 4924 nucleobindin 1 microtubule cytoskeleton Cellular component - PF4 5196 platelet factor 4 positive regulation of gene expression Biological process 10666185 CSRNP1 64651 cysteine-serine-rich nuclear protein 1 sequence-specific DNA binding transcription factor activity Molecular function 17726538 DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) integrin-mediated signaling pathway Biological process 19581412 GALNT1 2589 polypeptide N-acetylgalactosaminyltransferase 1 cellular protein metabolic process Biological process - GABRA6 2559 gamma-aminobutyric acid (GABA) A receptor, alpha 6 ion transmembrane transport Biological process - PLN 5350 phospholamban membrane Cellular component 19708671 CAV1 857 caveolin 1, caveolae protein, 22kDa regulation of blood coagulation Biological process 17848177 AIF1 199 allograft inflammatory factor 1 nucleus Cellular component - SH2D3C 10044 SH2 domain containing 3C protein binding Molecular function 24728074 TET1 80312 tet methylcytosine dioxygenase 1 iron ion binding Molecular function 19372391 RNMT 8731 RNA (guanine-7-) methyltransferase viral process Biological process - MOV10L1 54456 Mov10 RISC complex RNA helicase like 1 magnesium ion binding Molecular function 11839499 MVD 4597 mevalonate (diphospho) decarboxylase small molecule metabolic process Biological process - ASIC1 41 acid sensing (proton gated) ion channel 1 associative learning Biological process - OTC 5009 ornithine carbamoyltransferase citrulline biosynthetic process Biological process 2556444 GDPD4 220032 glycerophosphodiester phosphodiesterase domain containing 4 integral component of membrane Cellular component - KIFAP3 22920 kinesin-associated protein 3 protein localization Biological process - BAD 572 BCL2-associated agonist of cell death suppression by virus of host apoptotic process Biological process - CD55 1604 CD55 molecule, decay accelerating factor for complement (Cromer blood group) lipid binding Molecular function 12731067 HSP90AB1 3326 heat shock protein 90kDa alpha (cytosolic), class B member 1 nitric-oxide synthase regulator activity Molecular function - WDR83 84292 WD repeat domain 83 spliceosomal complex Cellular component 11991638 SLC34A1 6569 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 ossification Biological process - CDK20 23552 cyclin-dependent kinase 20 cytoplasm Cellular component - WT1 7490 Wilms tumor 1 sequence-specific DNA binding transcription factor activity Molecular function 7862533 TACR1 6869 tachykinin receptor 1 positive regulation of vascular permeability Biological process - NOC2L 26155 nucleolar complex associated 2 homolog (S. cerevisiae) histone binding Molecular function 16322561 NMI 9111 N-myc (and STAT) interactor protein binding Molecular function 10597290 ORC4 5000 origin recognition complex, subunit 4 cytoplasm Cellular component - RNF5 6048 ring finger protein 5, E3 ubiquitin protein ligase ubiquitin-protein transferase activity Molecular function 19269966 LAMC2 3918 laminin, gamma 2 heparin binding Molecular function - HEYL 26508 hes-related family bHLH transcription factor with YRPW motif-like atrioventricular valve morphogenesis Biological process - LIN7B 64130 lin-7 homolog B (C. elegans) asymmetric protein localization Biological process - CRKL 1399 v-crk avian sarcoma virus CT10 oncogene homolog-like organ morphogenesis Biological process - MBL2 4153 mannose-binding lectin (protein C) 2, soluble opsonization Biological process 2477488 ATXN3L 92552 ataxin 3-like mitochondrial membrane Cellular component - AAAS 8086 achalasia, adrenocortical insufficiency, alacrimia regulation of cellular response to heat Biological process - MAP2K2 5605 mitogen-activated protein kinase kinase 2 protein serine/threonine/tyrosine kinase activity Molecular function 19565474 SPIRE2 84501 spire-type actin nucleation factor 2 formin-nucleated actin cable assembly Biological process - RICTOR 253260 RPTOR independent companion of MTOR, complex 2 positive regulation of actin filament polymerization Biological process - RNF217 154214 ring finger protein 217 integral component of membrane Cellular component - ACTB 60 actin, beta RNA polymerase II distal enhancer sequence-specific DNA binding Molecular function 16217013 CTSZ 1522 cathepsin Z angiotensin maturation Biological process - DCP2 167227 decapping mRNA 2 histone mRNA catabolic process Biological process 18172165 TUBG2 27175 tubulin, gamma 2 microtubule nucleation Biological process - TRDN 10345 triadin protein binding, bridging Molecular function - ITSN1 6453 intersectin 1 (SH3 domain protein) proline-rich region binding Molecular function 20946875 OR4S2 219431 olfactory receptor, family 4, subfamily S, member 2 G-protein coupled receptor signaling pathway Biological process - TWF2 11344 twinfilin actin-binding protein 2 positive regulation of axon extension Biological process 17910947 FMR1 2332 fragile X mental retardation 1 microtubule Cellular component - PHF10 55274 PHD finger protein 10 npBAF complex Cellular component - LMX1A 4009 LIM homeobox transcription factor 1, alpha zinc ion binding Molecular function - OXA1L 5018 oxidase (cytochrome c) assembly 1-like negative regulation of ATPase activity Biological process 17936786 EDEM3 80267 ER degradation enhancer, mannosidase alpha-like 3 response to unfolded protein Biological process - AQP11 282679 aquaporin 11 proximal tubule development Biological process - IRF6 3664 interferon regulatory factor 6 keratinocyte proliferation Biological process - ELF3 1999 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) blastocyst development Biological process - TH 7054 tyrosine hydroxylase cellular response to glucose stimulus Biological process - SOX17 64321 SRY (sex determining region Y)-box 17 positive regulation of transcription, DNA-templated Biological process - NCK2 8440 NCK adaptor protein 2 endoplasmic reticulum Cellular component 16835242 RAB11FIP4 84440 RAB11 family interacting protein 4 (class II) midbody Cellular component 15601896 TMEM253 643382 transmembrane protein 253 integral component of membrane Cellular component - SEC24B 10427 SEC24 family member B zinc ion binding Molecular function - BNIP1 662 BCL2/adenovirus E1B 19kDa interacting protein 1 mitochondrion Cellular component - PTPN6 5777 protein tyrosine phosphatase, non-receptor type 6 SH3 domain binding Molecular function - PDE11A 50940 phosphodiesterase 11A perikaryon Cellular component - MED1 5469 mediator complex subunit 1 erythrocyte development Biological process - SLC22A12 116085 solute carrier family 22 (organic anion/urate transporter), member 12 plasma membrane Cellular component - ZBTB18 10472 zinc finger and BTB domain containing 18 in utero embryonic development Biological process - IRF7 3665 interferon regulatory factor 7 regulation of MyD88-dependent toll-like receptor signaling pathway Biological process - RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region endocardium morphogenesis Biological process - PRDX5 25824 peroxiredoxin 5 intracellular membrane-bounded organelle Cellular component 15785239 PAEP 5047 progestagen-associated endometrial protein extracellular region Cellular component - SLC6A1 6529 solute carrier family 6 (neurotransmitter transporter), member 1 synaptic transmission Biological process - VTI1A 143187 vesicle transport through interaction with t-SNAREs 1A SNARE complex Cellular component 15215310 ALAS1 211 5'-aminolevulinate synthase 1 porphyrin-containing compound metabolic process Biological process - TRPM7 54822 transient receptor potential cation channel, subfamily M, member 7 calcium-dependent cell-matrix adhesion Biological process - ATP5D 513 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) Cellular component 12539966 CYB5A 1528 cytochrome b5 type A (microsomal) hydrogen ion transmembrane transport Biological process 1712589 CYP2B6 1555 cytochrome P450, family 2, subfamily B, polypeptide 6 oxidation-reduction process Biological process 19651758 CYP46A1 10858 cytochrome P450, family 46, subfamily A, polypeptide 1 endoplasmic reticulum Cellular component 10377398 RRP8 23378 ribosomal RNA processing 8, methyltransferase, homolog (yeast) negative regulation of gene expression, epigenetic Biological process - DLG4 1742 discs, large homolog 4 (Drosophila) guanylate kinase activity Molecular function - PHIP 55023 pleckstrin homology domain interacting protein regulation of protein phosphorylation Biological process - ZNF865 100507290 zinc finger protein 865 DNA binding Molecular function - CHRNG 1146 cholinergic receptor, nicotinic, gamma (muscle) acetylcholine-gated channel complex Cellular component - SNX11 29916 sorting nexin 11 endosome Cellular component 23615901 SLIT2 9353 slit homolog 2 (Drosophila) negative regulation of endothelial cell migration Biological process 18345009 RASGEF1A 221002 RasGEF domain family, member 1A Ras guanyl-nucleotide exchange factor activity Molecular function 17121879 ENG 2022 endoglin response to hypoxia Biological process 18156205 BARHL2 343472 BarH-like homeobox 2 transcription, DNA-templated Biological process - NDUFA11 126328 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa cellular metabolic process Biological process - USP9X 8239 ubiquitin specific peptidase 9, X-linked protein deubiquitination Biological process 19135894 HOMER1 9456 homer scaffolding protein 1 neuronal cell body Cellular component - RB1 5925 retinoblastoma 1 striated muscle cell differentiation Biological process - ZSCAN31 64288 zinc finger and SCAN domain containing 31 sequence-specific DNA binding transcription factor activity Molecular function - ERVK-26 103539957 endogenous retrovirus group K, member 26 nucleolus Cellular component - DSEL 92126 dermatan sulfate epimerase-like carbohydrate metabolic process Biological process - COL22A1 169044 collagen, type XXII, alpha 1 collagen trimer Cellular component - MSI1 4440 musashi RNA-binding protein 1 RNA binding Molecular function 9790759 SHROOM3 57619 shroom family member 3 neural tube closure Biological process - NOTCH1 4851 notch 1 positive regulation of transcription, DNA-templated Biological process - SH2D5 400745 SH2 domain containing 5 postsynaptic density Cellular component - ZNF212 7988 zinc finger protein 212 transcription, DNA-templated Biological process - PFKFB2 5208 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 positive regulation of insulin secretion Biological process - ANKLE2 23141 ankyrin repeat and LEM domain containing 2 integral component of endoplasmic reticulum membrane Cellular component 22770216 TLR9 54106 toll-like receptor 9 positive regulation of interferon-beta production Biological process - AAAS 8086 achalasia, adrenocortical insufficiency, alacrimia hexose transport Biological process - FZD2 2535 frizzled class receptor 2 positive regulation of sequence-specific DNA binding transcription factor activity Biological process 18929644 CNST 163882 consortin, connexin sorting protein plasma membrane Cellular component 19864490 TNFSF8 944 tumor necrosis factor (ligand) superfamily, member 8 signal transduction Biological process 8391931 OBSL1 23363 obscurin-like 1 cytoplasm Cellular component 24793695 ADAM12 8038 ADAM metallopeptidase domain 12 cell adhesion Biological process - TNFAIP1 7126 tumor necrosis factor, alpha-induced protein 1 (endothelial) cell migration Biological process 19782033 BNIPL 149428 BCL2/adenovirus E1B 19kD interacting protein like nucleus Cellular component 11741952 SPIDR 23514 scaffolding protein involved in DNA repair protein binding Molecular function 23509288 NOC3L 64318 nucleolar complex associated 3 homolog (S. cerevisiae) chromatin binding Molecular function - PRMT7 54496 protein arginine methyltransferase 7 [myelin basic protein]-arginine N-methyltransferase activity Molecular function 15494416 PDLIM5 10611 PDZ and LIM domain 5 regulation of synapse assembly Biological process - EDA 1896 ectodysplasin A gene expression Biological process - KCNN2 3781 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 potassium ion transmembrane transport Biological process 17110593 LOC400927-CSNK1E 102800317 LOC400927-CSNK1E readthrough cytosol Cellular component - TFDP2 7029 transcription factor Dp-2 (E2F dimerization partner 2) regulation of transcription from RNA polymerase II promoter Biological process - UQCC2 84300 ubiquinol-cytochrome c reductase complex assembly factor 2 mitochondrial inner membrane Cellular component - YBX1 4904 Y box binding protein 1 CRD-mediated mRNA stability complex Cellular component 19029303 INPP5K 51763 inositol polyphosphate-5-phosphatase K negative regulation of calcium ion transport Biological process 12556481 ARV1 64801 ARV1 homolog (S. cerevisiae) Golgi apparatus Cellular component - SLC25A4 291 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 mitochondrial inner membrane Cellular component - CYFIP1 23191 cytoplasmic FMR1 interacting protein 1 small GTPase mediated signal transduction Biological process - PUM2 23369 pumilio RNA-binding family member 2 stress granule assembly Biological process - FAM175A 84142 family with sequence similarity 175, member A nucleus Cellular component - GLA 2717 galactosidase, alpha sphingolipid metabolic process Biological process - COL17A1 1308 collagen, type XVII, alpha 1 extracellular matrix disassembly Biological process - PDK4 5166 pyruvate dehydrogenase kinase, isozyme 4 response to starvation Biological process - UCK2 7371 uridine-cytidine kinase 2 pyrimidine nucleoside salvage Biological process - CXADR 1525 coxsackie virus and adenovirus receptor apicolateral plasma membrane Cellular component 15364909 SLC25A13 10165 solute carrier family 25 (aspartate/glutamate carrier), member 13 integral component of plasma membrane Cellular component 10642534 NSF 4905 N-ethylmaleimide-sensitive factor ATPase activity, coupled Molecular function - TEX35 84066 testis expressed 35 microtubule cytoskeleton Cellular component - ADRA1B 147 adrenoceptor alpha 1B protein heterodimerization activity Molecular function 22120526 UMOD 7369 uromodulin extrinsic component of membrane Cellular component 7873609 KLF15 28999 Kruppel-like factor 15 transcription, DNA-templated Biological process - DGKI 9162 diacylglycerol kinase, iota cytoplasm Cellular component 9830018 NPEPPS 9520 aminopeptidase puromycin sensitive cellular response to hypoxia Biological process 21056661 ZNF534 147658 zinc finger protein 534 nucleus Cellular component - CALM2 805 calmodulin 2 (phosphorylase kinase, delta) positive regulation of protein autophosphorylation Biological process 20668654 S1PR3 1903 sphingosine-1-phosphate receptor 3 inflammatory response Biological process - TFIP11 24144 tuftelin interacting protein 11 proteinaceous extracellular matrix Cellular component - ITPR2 3709 inositol 1,4,5-trisphosphate receptor, type 2 epidermal growth factor receptor signaling pathway Biological process - SLC4A9 83697 solute carrier family 4, sodium bicarbonate cotransporter, member 9 plasma membrane Cellular component - PIP5K1A 8394 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha nucleus Cellular component 15157668 APOA2 336 apolipoprotein A-II protein homodimerization activity Molecular function 17264082 ADA 100 adenosine deaminase xanthine biosynthetic process Biological process - TNFRSF21 27242 tumor necrosis factor receptor superfamily, member 21 negative regulation of interleukin-10 secretion Biological process - SSB 6741 Sjogren syndrome antigen B (autoantigen La) protein binding Molecular function 23552417 SLC9C1 285335 solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1 ion transmembrane transport Biological process - Sep-12 124404 septin 12 microtubule cytoskeleton Cellular component - PSEN2 5664 presenilin 2 growth cone Cellular component - OR2D2 120776 olfactory receptor, family 2, subfamily D, member 2 olfactory receptor activity Molecular function 9787077 PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta mast cell differentiation Biological process 20940048 EXOSC6 118460 exosome component 6 nuclear exosome (RNase complex) Cellular component - DENND4A 10260 DENN/MADD domain containing 4A Rab guanyl-nucleotide exchange factor activity Molecular function 20937701 KEL 3792 Kell blood group, metallo-endopeptidase negative regulation of potassium ion transmembrane transport Biological process - FGA 2243 fibrinogen alpha chain plasma membrane Cellular component - NDUFS4 4724 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) mitochondrial respiratory chain complex I assembly Biological process 11112787 DNMT3B 1789 DNA (cytosine-5-)-methyltransferase 3 beta regulation of gene expression by genetic imprinting Biological process - C8orf49 606553 chromosome 8 open reading frame 49 integral component of membrane Cellular component - APOB 338 apolipoprotein B leukocyte migration Biological process - PGLYRP4 57115 peptidoglycan recognition protein 4 N-acetylmuramoyl-L-alanine amidase activity Molecular function - SPN 6693 sialophorin negative regulation of type IV hypersensitivity Biological process - TGFB1I1 7041 transforming growth factor beta 1 induced transcript 1 positive regulation of epithelial to mesenchymal transition Biological process 18762808 ARHGEF10 9639 Rho guanine nucleotide exchange factor (GEF) 10 Rho guanyl-nucleotide exchange factor activity Molecular function 16896804 SLC18A3 6572 solute carrier family 18 (vesicular acetylcholine transporter), member 3 ammonium transmembrane transport Biological process 8071310 NPHS1 4868 nephrosis 1, congenital, Finnish type (nephrin) protein domain specific binding Molecular function - AGXT 189 alanine-glyoxylate aminotransferase response to glucocorticoid Biological process - CXCR3 2833 chemokine (C-X-C motif) receptor 3 positive regulation of release of sequestered calcium ion into cytosol Biological process 12782716 SLC8A2 6543 solute carrier family 8 (sodium/calcium exchanger), member 2 integral component of membrane Cellular component - CRX 1406 cone-rod homeobox retina development in camera-type eye Biological process - STEAP3 55240 STEAP family member 3, metalloreductase ferric-chelate reductase activity Molecular function - PPM1F 9647 protein phosphatase, Mg2+/Mn2+ dependent, 1F intrinsic apoptotic signaling pathway Biological process 11559703 ARFIP2 23647 ADP-ribosylation factor interacting protein 2 trans-Golgi network membrane Cellular component 23695357 ATP12A 479 ATPase, H+/K+ transporting, nongastric, alpha polypeptide basolateral plasma membrane Cellular component - PRPF40A 55660 PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) cell division Biological process - DDX41 51428 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 membrane Cellular component 19946888 EID3 493861 EP300 interacting inhibitor of differentiation 3 post-translational protein modification Biological process - EXOSC8 11340 exosome component 8 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay Biological process - DYRK1B 9149 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B protein kinase activity Molecular function 11980910 ITIH2 3698 inter-alpha-trypsin inhibitor heavy chain 2 extracellular region Cellular component 14718574 CTBP1 1487 C-terminal binding protein 1 transcription factor binding Molecular function 16609867 PRKAR1A 5573 protein kinase, cAMP-dependent, regulatory, type I, alpha small molecule metabolic process Biological process - CYP8B1 1582 cytochrome P450, family 8, subfamily B, polypeptide 1 integral component of membrane Cellular component - PRKAA1 5562 protein kinase, AMP-activated, alpha 1 catalytic subunit protein binding Molecular function 16306228 PYCARD 29108 PYD and CARD domain containing regulation of intrinsic apoptotic signaling pathway Biological process 14730312 EPS8 2059 epidermal growth factor receptor pathway substrate 8 Rac GTPase binding Molecular function - YWHAH 7533 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta glucocorticoid receptor binding Molecular function 9079630 ALAS1 211 5'-aminolevulinate synthase 1 cytoplasm Cellular component - F2 2147 coagulation factor II (thrombin) peptidyl-glutamic acid carboxylation Biological process - AP1G2 8906 adaptor-related protein complex 1, gamma 2 subunit protein binding Molecular function 12505986 FAM90A1 55138 family with sequence similarity 90, member A1 zinc ion binding Molecular function - HAS2 3037 hyaluronan synthase 2 cellular response to tumor necrosis factor Biological process 20522558 SSH2 85464 slingshot protein phosphatase 2 DNA binding Molecular function - MLLT6 4302 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 regulation of transcription, DNA-templated Biological process 8058765 CLEC3B 7123 C-type lectin domain family 3, member B cellular response to transforming growth factor beta stimulus Biological process 7589422 VWA5A 4013 von Willebrand factor A domain containing 5A nucleoplasm Cellular component - RYR1 6261 ryanodine receptor 1 (skeletal) junctional membrane complex Cellular component - MED6 10001 mediator complex subunit 6 transcription coactivator activity Molecular function 12037571 RPA2 6118 replication protein A2, 32kDa DNA damage response, detection of DNA damage Biological process - OTOG 340990 otogelin extracellular space Cellular component - TRBC2 28638 T cell receptor beta constant 2 integral component of membrane Cellular component - TSG101 7251 tumor susceptibility 101 regulation of viral release from host cell Biological process 11595185 CD274 29126 CD274 molecule protein binding Molecular function 21982860 NDUFC2-KCTD14 100532726 NDUFC2-KCTD14 readthrough NADH dehydrogenase (ubiquinone) activity Molecular function - LAT 27040 linker for activation of T cells mast cell granule Cellular component - DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) focal adhesion Cellular component 21423176 DMD 1756 dystrophin cardiac muscle cell action potential Biological process 20080623 RSG1 79363 REM2 and RAB-like small GTPase 1 small GTPase mediated signal transduction Biological process - RNF135 84282 ring finger protein 135 protein ubiquitination Biological process - CNOT1 23019 CCR4-NOT transcription complex, subunit 1 extracellular space Cellular component 22664934 PSMB10 5699 proteasome (prosome, macropain) subunit, beta type, 10 apoptotic process Biological process - DLD 1738 dihydrolipoamide dehydrogenase mitochondrial matrix Cellular component - HS6ST3 266722 heparan sulfate 6-O-sulfotransferase 3 heparan sulfate proteoglycan biosynthetic process, enzymatic modification Biological process - EIF3A 8661 eukaryotic translation initiation factor 3, subunit A protein binding Molecular function 11169732 GCK 2645 glucokinase (hexokinase 4) glucose metabolic process Biological process - TIPIN 54962 TIMELESS interacting protein cell division Biological process - PNPLA8 50640 patatin-like phospholipase domain containing 8 arachidonic acid metabolic process Biological process 10833412 SLC31A1 1317 solute carrier family 31 (copper transporter), member 1 copper ion import into cell Biological process - TCF12 6938 transcription factor 12 nucleus Cellular component - IGF2BP2 10644 insulin-like growth factor 2 mRNA binding protein 2 mRNA 3'-UTR binding Molecular function 20080952 GNG8 94235 guanine nucleotide binding protein (G protein), gamma 8 cellular response to glucagon stimulus Biological process - RPS23 6228 ribosomal protein S23 cytosolic small ribosomal subunit Cellular component 15883184 DOHH 83475 deoxyhypusine hydroxylase/monooxygenase cytosol Cellular component - IRGM 345611 immunity-related GTPase family, M cell projection Cellular component - TRIM62 55223 tripartite motif containing 62 positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process 23077300 USP2 9099 ubiquitin specific peptidase 2 nucleus Cellular component - SCAF4 57466 SR-related CTD-associated factor 4 nucleoplasm Cellular component - TOB1 10140 transducer of ERBB2, 1 negative regulation of translation Biological process 23236473 ABL1 25 ABL proto-oncogene 1, non-receptor tyrosine kinase positive regulation of cytosolic calcium ion concentration Biological process 24367707 ALDH1A3 220 aldehyde dehydrogenase 1 family, member A3 oxidation-reduction process Biological process - RFC2 5982 replication factor C (activator 1) 2, 40kDa transcription-coupled nucleotide-excision repair Biological process - CERK 64781 ceramide kinase small molecule metabolic process Biological process - PSMC6 5706 proteasome (prosome, macropain) 26S subunit, ATPase, 6 regulation of cellular amino acid metabolic process Biological process - SYT13 57586 synaptotagmin XIII plasma membrane Cellular component - HTR6 3362 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled response to drug Biological process - COL3A1 1281 collagen, type III, alpha 1 digestive tract development Biological process - BBS7 55212 Bardet-Biedl syndrome 7 nonmotile primary cilium assembly Biological process - GOLPH3 64083 golgi phosphoprotein 3 (coat-protein) Golgi apparatus Cellular component 18410729 UCK2 7371 uridine-cytidine kinase 2 nucleoside kinase activity Molecular function - NDUFAB1 4706 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa small molecule metabolic process Biological process - OR2A7 401427 olfactory receptor, family 2, subfamily A, member 7 detection of chemical stimulus involved in sensory perception Biological process - UAP1 6675 UDP-N-acetylglucosamine pyrophosphorylase 1 UDP-N-acetylglucosamine diphosphorylase activity Molecular function - DBH 1621 dopamine beta-hydroxylase (dopamine beta-monooxygenase) homoiothermy Biological process - BAIAP3 8938 BAI1-associated protein 3 cell Cellular component 9790924 CYBA 1535 cytochrome b-245, alpha polypeptide cellular response to mechanical stimulus Biological process - MYOD1 4654 myogenic differentiation 1 chromatin DNA binding Molecular function - ZNF148 7707 zinc finger protein 148 gamete generation Biological process - ABHD14B 84836 abhydrolase domain containing 14B nucleus Cellular component - SPHK1 8877 sphingosine kinase 1 positive regulation of neurotransmitter secretion Biological process - FEN1 2237 flap structure-specific endonuclease 1 nucleolus Cellular component - ZBED2 79413 zinc finger, BED-type containing 2 DNA binding Molecular function - OR2AK2 391191 olfactory receptor, family 2, subfamily AK, member 2 G-protein coupled receptor signaling pathway Biological process - TBL3 10607 transducin (beta)-like 3 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Biological process - LRRTM2 26045 leucine rich repeat transmembrane neuronal 2 neurexin family protein binding Molecular function - IL1RN 3557 interleukin 1 receptor antagonist response to interleukin-4 Biological process - ST14 6768 suppression of tumorigenicity 14 (colon carcinoma) keratinocyte differentiation Biological process 18843291 LSM10 84967 LSM10, U7 small nuclear RNA associated nucleoplasm Cellular component - FARS2 10667 phenylalanyl-tRNA synthetase 2, mitochondrial cytoplasm Cellular component - RPS6KA5 9252 ribosomal protein S6 kinase, 90kDa, polypeptide 5 intracellular signal transduction Biological process 9687510 TRIM27 5987 tripartite motif containing 27 negative regulation of viral release from host cell Biological process - CDC25B 994 cell division cycle 25B positive regulation of protein kinase activity Biological process - ITPK1 3705 inositol-tetrakisphosphate 1-kinase magnesium ion binding Molecular function - PAK3 5063 p21 protein (Cdc42/Rac)-activated kinase 3 innate immune response Biological process - NOTCH3 4854 notch 3 positive regulation of smooth muscle cell proliferation Biological process - OC90 729330 otoconin 90 biological_process Biological process - PFKFB3 5209 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 dephosphorylation Biological process - MED30 90390 mediator complex subunit 30 thyroid hormone receptor binding Molecular function 10198638 CCS 9973 copper chaperone for superoxide dismutase copper ion transmembrane transport Biological process 9726962 PPP2R3A 5523 protein phosphatase 2, regulatory subunit B'', alpha regulation of protein phosphatase type 2A activity Biological process 8392071 EYA1 2138 EYA transcriptional coactivator and phosphatase 1 histone dephosphorylation Biological process 19234442 CLDN5 7122 claudin 5 identical protein binding Molecular function - SCX 642658 scleraxis basic helix-loop-helix transcription factor heart valve formation Biological process - GHSR 2693 growth hormone secretagogue receptor peptide hormone binding Molecular function - PRKCZ 5590 protein kinase C, zeta positive regulation of ERK1 and ERK2 cascade Biological process 11035106 CDK5 1020 cyclin-dependent kinase 5 cell cycle Biological process - BMP4 652 bone morphogenetic protein 4 cranial suture morphogenesis Biological process - BRS3 680 bombesin-like receptor 3 bombesin receptor activity Molecular function - LDHB 3945 lactate dehydrogenase B NAD binding Molecular function - PTEN 5728 phosphatase and tensin homolog protein tyrosine/serine/threonine phosphatase activity Molecular function - CTDP1 9150 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 positive regulation of viral transcription Biological process - CHRNB4 1143 cholinergic receptor, nicotinic, beta 4 (neuronal) synaptic transmission, cholinergic Biological process 1330682 APBA1 320 amyloid beta (A4) precursor protein-binding, family A, member 1 gamma-aminobutyric acid secretion Biological process - PCDHB3 56132 protocadherin beta 3 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Biological process 11322959 CETN1 1068 centrin, EF-hand protein, 1 mitotic nuclear division Biological process - TNFSF4 7292 tumor necrosis factor (ligand) superfamily, member 4 positive regulation of memory T cell differentiation Biological process - MED4 29079 mediator complex subunit 4 transcription from RNA polymerase II promoter Biological process 10882111 TGM3 7053 transglutaminase 3 keratinocyte differentiation Biological process 24643 POLR2A 5430 polymerase (RNA) II (DNA directed) polypeptide A, 220kDa DNA binding Molecular function 7622068 ZNF225 7768 zinc finger protein 225 metal ion binding Molecular function - ZNF880 400713 zinc finger protein 880 regulation of transcription, DNA-templated Biological process - HIST1H1C 3006 histone cluster 1, H1c poly(A) RNA binding Molecular function 22658674 OTX2 5015 orthodenticle homeobox 2 protein heterodimerization activity Molecular function - TSC2 7249 tuberous sclerosis 2 protein localization Biological process - SNAP23 8773 synaptosomal-associated protein, 23kDa vesicle targeting Biological process 8663154 PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 negative regulation of programmed cell death Biological process 16432160 CHEK2 11200 checkpoint kinase 2 nucleoplasm Cellular component - POLA2 23649 polymerase (DNA directed), alpha 2, accessory subunit DNA strand elongation involved in DNA replication Biological process - ACOT8 10005 acyl-CoA thioesterase 8 viral process Biological process - DLG4 1742 discs, large homolog 4 (Drosophila) cortical cytoskeleton Cellular component 12151521 SYTL4 94121 synaptotagmin-like 4 transport vesicle membrane Cellular component - AVIL 10677 advillin cilium morphogenesis Biological process 20393563 DBT 1629 dihydrolipoamide branched chain transacylase E2 small molecule metabolic process Biological process - PRKACG 5568 protein kinase, cAMP-dependent, catalytic, gamma energy reserve metabolic process Biological process - PTGDS 5730 prostaglandin D2 synthase 21kDa (brain) prostaglandin-D synthase activity Molecular function - CLU 1191 clusterin mitochondrion Cellular component 16113678 PRSS27 83886 protease, serine 27 extracellular region Cellular component - GGT3P 2679 gamma-glutamyltransferase 3 pseudogene glutathione hydrolase activity Molecular function - VCAM1 7412 vascular cell adhesion molecule 1 cell adhesion Biological process 16809613 MRLN 100507027 myoregulin integral component of membrane Cellular component - MED24 9862 mediator complex subunit 24 stem cell maintenance Biological process - TNNC1 7134 troponin C type 1 (slow) calcium ion binding Molecular function 12840750 CALM2 805 calmodulin 2 (phosphorylase kinase, delta) positive regulation of nitric-oxide synthase activity Biological process - RPS29 6235 ribosomal protein S29 translational elongation Biological process - ASB16 92591 ankyrin repeat and SOCS box containing 16 intracellular signal transduction Biological process - ZNF354A 6940 zinc finger protein 354A kidney development Biological process - LHPP 64077 phospholysine phosphohistidine inorganic pyrophosphate phosphatase protein dephosphorylation Biological process - ZNF300 91975 zinc finger protein 300 regulation of transcription, DNA-templated Biological process - KIF5A 3798 kinesin family member 5A protein binding Molecular function 22705394 PCSK2 5126 proprotein convertase subtilisin/kexin type 2 transport vesicle Cellular component - TPRN 286262 taperin stereocilium Cellular component - DLL1 28514 delta-like 1 (Drosophila) hemopoiesis Biological process 11581320 IPO11 51194 importin 11 Ran GTPase binding Molecular function - GNE 10020 glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase cellular protein metabolic process Biological process - UBB 7314 ubiquitin B mitochondrion Cellular component 17571083 COBL 23242 cordon-bleu WH2 repeat protein ruffle Cellular component - REV1 51455 REV1, polymerase (DNA directed) damaged DNA binding Molecular function - CDC14B 8555 cell division cycle 14B activation of anaphase-promoting complex activity Biological process 18662541 GRM6 2916 glutamate receptor, metabotropic 6 G-protein coupled glutamate receptor signaling pathway Biological process 23452348 GRM4 2914 glutamate receptor, metabotropic 4 group III metabotropic glutamate receptor activity Molecular function - DHRS4 10901 dehydrogenase/reductase (SDR family) member 4 protein tetramerization Biological process 18571493 PSMB4 5692 proteasome (prosome, macropain) subunit, beta type, 4 programmed cell death Biological process - CTPS1 1503 CTP synthase 1 glutamine metabolic process Biological process - PCGF1 84759 polycomb group ring finger 1 regulation of transcription, DNA-templated Biological process - RPS6KA5 9252 ribosomal protein S6 kinase, 90kDa, polypeptide 5 protein phosphorylation Biological process 9687510 USP17L11 100287178 ubiquitin specific peptidase 17-like family member 11 endoplasmic reticulum Cellular component - PPM1E 22843 protein phosphatase, Mg2+/Mn2+ dependent, 1E protein serine/threonine phosphatase activity Molecular function 20801214 ACR 49 acrosin protein complex Cellular component 7521127 FMNL1 752 formin-like 1 cell cortex Cellular component - MKNK2 2872 MAP kinase interacting serine/threonine kinase 2 nucleoplasm Cellular component - UHRF1 29128 ubiquitin-like with PHD and ring finger domains 1 cell cycle Biological process - OSR2 116039 odd-skipped related transciption factor 2 mesonephros development Biological process - CACNA1S 779 calcium channel, voltage-dependent, L type, alpha 1S subunit axon guidance Biological process - SNRNP27 11017 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) mRNA processing Biological process - NKX2-5 1482 NK2 homeobox 5 spleen development Biological process 8900537 COX7A2 1347 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) extracellular exosome Cellular component 23376485 OR13F1 138805 olfactory receptor, family 13, subfamily F, member 1 adenylate cyclase-activating adrenergic receptor signaling pathway Biological process - OR1G1 8390 olfactory receptor, family 1, subfamily G, member 1 detection of chemical stimulus involved in sensory perception Biological process - ROR2 4920 receptor tyrosine kinase-like orphan receptor 2 positive regulation of transcription, DNA-templated Biological process - SLC19A3 80704 solute carrier family 19 (thiamine transporter), member 3 integral component of membrane Cellular component 11136550 COL7A1 1294 collagen, type VII, alpha 1 serine-type endopeptidase inhibitor activity Molecular function - CCL14 6358 chemokine (C-C motif) ligand 14 cell chemotaxis Biological process - YAP1 10413 Yes-associated protein 1 transcription corepressor activity Molecular function 18158288 SPARC 6678 secreted protein, acidic, cysteine-rich (osteonectin) platelet alpha granule lumen Cellular component - PIK3C2A 5286 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha phosphatidylinositol 3-kinase activity Molecular function 17371240 SLC7A1 6541 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 L-ornithine transmembrane transporter activity Molecular function - ARL4D 379 ADP-ribosylation factor-like 4D plasma membrane Cellular component 17398095 PPIL2 23759 peptidylprolyl isomerase (cyclophilin)-like 2 leukocyte migration Biological process - C1GALT1C1 29071 C1GALT1-specific chaperone 1 protein binding Molecular function 21496458 DUSP10 11221 dual specificity phosphatase 10 nucleoplasm Cellular component - MID1 4281 midline 1 microtubule cytoskeleton organization Biological process 10077590 PPEF1 5475 protein phosphatase, EF-hand calcium binding domain 1 iron ion binding Molecular function - BHLHA15 168620 basic helix-loop-helix family, member a15 cell maturation Biological process - RGS6 9628 regulator of G-protein signaling 6 Golgi apparatus Cellular component - NUP205 23165 nucleoporin 205kDa viral life cycle Biological process - SFRP2 6423 secreted frizzled-related protein 2 endopeptidase activator activity Molecular function - CRISP3 10321 cysteine-rich secretory protein 3 extracellular region Cellular component 12009203 HIST2H4B 554313 histone cluster 2, H4b nucleus Cellular component 14585971 SPAG16 79582 sperm associated antigen 16 motile cilium Cellular component - HUWE1 10075 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase nucleoplasm Cellular component - SRPX 8406 sushi-repeat containing protein, X-linked positive regulation of extrinsic apoptotic signaling pathway in absence of ligand Biological process - TSEN34 79042 TSEN34 tRNA splicing endonuclease subunit nucleoplasm Cellular component - ITGA4 3676 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) fibronectin binding Molecular function - TSNARE1 203062 t-SNARE domain containing 1 endomembrane system Cellular component - SEL1L 6400 sel-1 suppressor of lin-12-like (C. elegans) integral component of membrane Cellular component - FA2H 79152 fatty acid 2-hydroxylase iron ion binding Molecular function - TACC3 10460 transforming, acidic coiled-coil containing protein 3 astral microtubule organization Biological process - SCRT2 85508 scratch family zinc finger 2 nuclear chromatin Cellular component - SH3GLB1 51100 SH3-domain GRB2-like endophilin B1 receptor catabolic process Biological process 20643123 EVL 51466 Enah/Vasp-like positive regulation of actin filament polymerization Biological process - TSPY10 100289087 testis specific protein, Y-linked 10 gonadal mesoderm development Biological process - PLXNB3 5365 plexin B3 integral component of membrane Cellular component - CWC22 57703 CWC22 spliceosome-associated protein spliceosomal complex Cellular component 11991638 TGFBI 7045 transforming growth factor, beta-induced, 68kDa protein binding Molecular function 19478074 GSTA1 2938 glutathione S-transferase alpha 1 glutathione transferase activity Molecular function 1731620 RNF121 55298 ring finger protein 121 ER-associated ubiquitin-dependent protein catabolic process Biological process - NKD2 85409 naked cuticle homolog 2 (Drosophila) positive regulation of protein processing Biological process 15064403 NPR3 4883 natriuretic peptide receptor 3 G-protein coupled peptide receptor activity Molecular function - AIM2 9447 absent in melanoma 2 cytoplasm Cellular component 19158676 SPATA32 124783 spermatogenesis associated 32 perinuclear region of cytoplasm Cellular component - ALS2 57679 amyotrophic lateral sclerosis 2 (juvenile) endosomal transport Biological process - HIST2H2BF 440689 histone cluster 2, H2bf nuclear nucleosome Cellular component - NLRC4 58484 NLR family, CARD domain containing 4 interleukin-1 beta secretion Biological process 15882992 PNN 5411 pinin, desmosome associated protein mRNA splicing, via spliceosome Biological process 11991638 ACAN 176 aggrecan proteinaceous extracellular matrix Cellular component - ANXA2 302 annexin A2 endosome Cellular component 18767904 SSBP3 23648 single stranded DNA binding protein 3 nucleus Cellular component - KHK 3795 ketohexokinase (fructokinase) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate Biological process - PPP1R3D 5509 protein phosphatase 1, regulatory subunit 3D enzyme binding Molecular function - DLAT 1737 dihydrolipoamide S-acetyltransferase dihydrolipoyllysine-residue acetyltransferase activity Molecular function 3191998 MAPK12 6300 mitogen-activated protein kinase 12 mitochondrion organization Biological process - CD209 30835 CD209 molecule heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Biological process 1518869 NXPH2 11249 neurexophilin 2 neuropeptide signaling pathway Biological process 9570794 CEP250 11190 centrosomal protein 250kDa cytosol Cellular component - OR11H12 440153 olfactory receptor, family 11, subfamily H, member 12 olfactory receptor activity Molecular function - BMP4 652 bone morphogenetic protein 4 chemoattractant activity Molecular function 12631064 CHD7 55636 chromodomain helicase DNA binding protein 7 regulation of neurogenesis Biological process - KANK1 23189 KN motif and ankyrin repeat domains 1 negative regulation of ruffle assembly Biological process 19171758 DCTN2 10540 dynactin 2 (p50) mitotic spindle organization Biological process - AKAP8 10270 A kinase (PRKA) anchor protein 8 poly(A) RNA binding Molecular function 22658674 HSPA8 3312 heat shock 70kDa protein 8 membrane Cellular component 19946888 PDGFA 5154 platelet-derived growth factor alpha polypeptide positive regulation of mesenchymal cell proliferation Biological process - CDH2 1000 cadherin 2, type 1, N-cadherin (neuronal) calcium ion binding Molecular function - PCM1 5108 pericentriolar material 1 identical protein binding Molecular function - NCBP2 22916 nuclear cap binding protein subunit 2, 20kDa ncRNA metabolic process Biological process - T 6862 T, brachyury homolog (mouse) RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription Molecular function - NBPF20 100288142 neuroblastoma breakpoint family, member 20 cytoplasm Cellular component - SSTR2 6752 somatostatin receptor 2 cellular response to estradiol stimulus Biological process - ACAA2 10449 acetyl-CoA acyltransferase 2 mitochondrial inner membrane Cellular component - TOLLIP 54472 toll interacting protein cytoplasm Cellular component 11441107 FABP3 2170 fatty acid binding protein 3, muscle and heart long-chain fatty acid transporter activity Molecular function - OTX2 5015 orthodenticle homeobox 2 eye photoreceptor cell fate commitment Biological process - FLOT2 2319 flotillin 2 protein heterodimerization activity Molecular function 21696602 CNOT8 9337 CCR4-NOT transcription complex, subunit 8 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay Biological process 20065043 ADAP1 11033 ArfGAP with dual PH domains 1 regulation of GTPase activity Biological process 10333475 HOPX 84525 HOP homeobox nucleus Cellular component 17192267 SYNGR2 9144 synaptogyrin 2 synaptic vesicle membrane Cellular component - CX3CL1 6376 chemokine (C-X3-C motif) ligand 1 defense response Biological process 12714508 IHH 3549 indian hedgehog embryonic camera-type eye morphogenesis Biological process - PSMA8 143471 proteasome (prosome, macropain) subunit, alpha type, 8 innate immune response Biological process - SLC17A5 26503 solute carrier family 17 (acidic sugar transporter), member 5 integral component of plasma membrane Cellular component 10581036 POLR2E 5434 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa viral process Biological process - GCM1 8521 glial cells missing homolog 1 (Drosophila) protein binding Molecular function 23867755 TAL1 6886 T-cell acute lymphocytic leukemia 1 positive regulation of protein complex assembly Biological process 20855495 ING4 51147 inhibitor of growth family, member 4 histone H4-K8 acetylation Biological process 16387653 PARVB 29780 parvin, beta cytoskeleton Cellular component - DPPA3 359787 developmental pluripotency associated 3 embryonic cleavage Biological process - PFKFB1 5207 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 fructose-6-phosphate binding Molecular function - EZR 7430 ezrin actin filament bundle assembly Biological process 10793131 ZC3H8 84524 zinc finger CCCH-type containing 8 apoptotic process Biological process - PRPF6 24148 pre-mRNA processing factor 6 RNA binding Molecular function 20797886 SCNN1A 6337 sodium channel, non voltage gated 1 alpha subunit protein binding Molecular function 11244092 TLE1 7088 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) nucleoplasm Cellular component - HLA-DRB4 3126 major histocompatibility complex, class II, DR beta 4 Golgi membrane Cellular component - ITGB1 3688 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) positive regulation of cell migration Biological process - TBP 6908 TATA box binding protein positive regulation of transcription, DNA-templated Biological process - ZNF814 730051 zinc finger protein 814 metal ion binding Molecular function - XBP1 7494 X-box binding protein 1 cytoplasm Cellular component - GSG2 83903 germ cell associated 2 (haspin) intracellular signal transduction Biological process 11228240 MRPS7 51081 mitochondrial ribosomal protein S7 translation Biological process - CYP2A6 1548 cytochrome P450, family 2, subfamily A, polypeptide 6 coumarin metabolic process Biological process 19651758 CNTN6 27255 contactin 6 anchored component of membrane Cellular component - AWAT1 158833 acyl-CoA wax alcohol acyltransferase 1 integral component of membrane Cellular component - BFAR 51283 bifunctional apoptosis regulator ubiquitin protein ligase activity Molecular function 21068390 INHBA 3624 inhibin, beta A negative regulation of phosphorylation Biological process 12456957 LIG4 3981 ligase IV, DNA, ATP-dependent DNA ligase activity Molecular function - MECP2 4204 methyl CpG binding protein 2 neuron maturation Biological process - FKBP5 2289 FK506 binding protein 5 FK506 binding Molecular function 9001212 DGKG 1608 diacylglycerol kinase, gamma 90kDa ATP binding Molecular function - PRB2 653247 proline-rich protein BstNI subfamily 2 biological_process Biological process - ADAM32 203102 ADAM metallopeptidase domain 32 proteolysis Biological process - IL1RAP 3556 interleukin 1 receptor accessory protein inflammatory response Biological process - PTGDR 5729 prostaglandin D2 receptor (DP) inflammatory response Biological process - SETD3 84193 SET domain containing 3 positive regulation of transcription, DNA-templated Biological process - OVGP1 5016 oviductal glycoprotein 1, 120kDa carbohydrate metabolic process Biological process - CLN8 2055 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) visual perception Biological process - BEST4 266675 bestrophin 4 chloride channel activity Molecular function - SEL1L 6400 sel-1 suppressor of lin-12-like (C. elegans) Notch signaling pathway Biological process - NEUROG3 50674 neurogenin 3 positive regulation of transcription from RNA polymerase II promoter Biological process 16511571 ZMYND11 10771 zinc finger, MYND-type containing 11 viral process Biological process - SHANK3 85358 SH3 and multiple ankyrin repeat domains 3 positive regulation of dendritic spine development Biological process 21795692 NUP35 129401 nucleoporin 35kDa nucleoplasm Cellular component - BBS1 582 Bardet-Biedl syndrome 1 protein localization to cilium Biological process 23943788 STAP1 26228 signal transducing adaptor family member 1 negative regulation of macrophage chemotaxis Biological process - ADAM8 101 ADAM metallopeptidase domain 8 positive regulation of protein kinase B signaling Biological process - NTAN1 123803 N-terminal asparagine amidase memory Biological process - SORBS2 8470 sorbin and SH3 domain containing 2 perinuclear region of cytoplasm Cellular component - RHOBTB2 23221 Rho-related BTB domain containing 2 GTP binding Molecular function - CRLF1 9244 cytokine receptor-like factor 1 receptor activity Molecular function 9686600 TAL2 6887 T-cell acute lymphocytic leukemia 2 midbrain development Biological process - U2AF2 11338 U2 small nuclear RNA auxiliary factor 2 mRNA export from nucleus Biological process - CXCL12 6387 chemokine (C-X-C motif) ligand 12 positive regulation of cell adhesion Biological process 23620790 EPAS1 2034 endothelial PAS domain protein 1 surfactant homeostasis Biological process - RORA 6095 RAR-related orphan receptor A zinc ion binding Molecular function - ARHGEF9 23229 Cdc42 guanine nucleotide exchange factor (GEF) 9 ion transmembrane transport Biological process - HLCS 3141 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) nuclear lamina Cellular component 14613969 COPE 11316 coatomer protein complex, subunit epsilon protein transport Biological process - NME6 10201 NME/NM23 nucleoside diphosphate kinase 6 negative regulation of cell growth Biological process 10618642 PLAA 9373 phospholipase A2-activating protein signal transduction Biological process 9931468 B3GALTL 145173 beta 1,3-galactosyltransferase-like protein O-linked fucosylation Biological process - CC2D1B 200014 coiled-coil and C2 domain containing 1B negative regulation of transcription from RNA polymerase II promoter Biological process - AZIN2 113451 antizyme inhibitor 2 putrescine transport Biological process - AKAP8 10270 A kinase (PRKA) anchor protein 8 nuclear matrix Cellular component - ATP6V0D2 245972 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 insulin receptor signaling pathway Biological process - NOTCH1 4851 notch 1 forebrain development Biological process - FN1 2335 fibronectin 1 collagen binding Molecular function 3024962 ANKRD27 84079 ankyrin repeat domain 27 (VPS9 domain) Rab GTPase binding Molecular function 16525121 TFPT 29844 TCF3 (E2A) fusion partner (in childhood Leukemia) Ino80 complex Cellular component 21303910 CCL5 6352 chemokine (C-C motif) ligand 5 exocytosis Biological process 10734056 TNRC6A 27327 trinucleotide repeat containing 6A cytoplasmic mRNA processing body Cellular component 20616046 GFER 2671 growth factor, augmenter of liver regeneration growth factor activity Molecular function - VPS11 55823 vacuolar protein sorting 11 homolog (S. cerevisiae) endosomal vesicle fusion Biological process 21148287 B3GALTL 145173 beta 1,3-galactosyltransferase-like cellular protein metabolic process Biological process - HHEX 3087 hematopoietically expressed homeobox RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function 15016828 LRRK2 120892 leucine-rich repeat kinase 2 peroxidase inhibitor activity Molecular function 21850687 NDUFA6 4700 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa small molecule metabolic process Biological process - BRD7 29117 bromodomain containing 7 p53 binding Molecular function 20228809 SH2D4A 63898 SH2 domain containing 4A protein binding Molecular function 16189514 CACNA1H 8912 calcium channel, voltage-dependent, T type, alpha 1H subunit muscle organ development Biological process 9670923 ACVR1 90 activin A receptor, type I activin receptor complex Cellular component 8242742 ZNF558 148156 zinc finger protein 558 regulation of transcription, DNA-templated Biological process - IL16 3603 interleukin 16 immune response Biological process 9144227 CDC25A 993 cell division cycle 25A cellular response to UV Biological process 19966869 UGT1A8 54576 UDP glucuronosyltransferase 1 family, polypeptide A8 xenobiotic glucuronidation Biological process 20056724 EYA2 2139 EYA transcriptional coactivator and phosphatase 2 transcription, DNA-templated Biological process - TRIOBP 11078 TRIO and F-actin binding protein ubiquitin protein ligase binding Molecular function 18194665 INPP5E 56623 inositol polyphosphate-5-phosphatase, 72 kDa Golgi cisterna membrane Cellular component - INPP5K 51763 inositol polyphosphate-5-phosphatase K negative regulation of glycogen (starch) synthase activity Biological process - FGF19 9965 fibroblast growth factor 19 insulin receptor signaling pathway Biological process - TRIM36 55521 tripartite motif containing 36 ubiquitin-protein transferase activity Molecular function - PCDHAC2 56134 protocadherin alpha subfamily C, 2 homophilic cell adhesion via plasma membrane adhesion molecules Biological process - NCKAP1 10787 NCK-associated protein 1 establishment or maintenance of actin cytoskeleton polarity Biological process - TAF1B 9014 TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa protein binding Molecular function 17318177 AMBP 259 alpha-1-microglobulin/bikunin precursor heme catabolic process Biological process 11877257 KLHL20 27252 kelch-like family member 20 actin cytoskeleton Cellular component 10888605 MECP2 4204 methyl CpG binding protein 2 respiratory gaseous exchange Biological process - PHF23 79142 PHD finger protein 23 zinc ion binding Molecular function - CEP70 80321 centrosomal protein 70kDa nuclear membrane Cellular component - TACC2 10579 transforming, acidic coiled-coil containing protein 2 microtubule cytoskeleton organization Biological process - ACOT9 23597 acyl-CoA thioesterase 9 acyl-CoA metabolic process Biological process - PTK2 5747 protein tyrosine kinase 2 positive regulation of protein kinase B signaling Biological process 15166238 APLN 8862 apelin extracellular region Cellular component - PLA2G10 8399 phospholipase A2, group X phosphatidylglycerol acyl-chain remodeling Biological process - KCNN2 3781 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 calmodulin binding Molecular function - LEO1 123169 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) nucleoplasm Cellular component - VTN 7448 vitronectin receptor-mediated endocytosis Biological process - CMKLR1 1240 chemerin chemokine-like receptor 1 G-protein coupled receptor signaling pathway Biological process 9603476 TRPM7 54822 transient receptor potential cation channel, subfamily M, member 7 calcium ion transmembrane transport Biological process - ADAMTS3 9508 ADAM metallopeptidase with thrombospondin type 1 motif, 3 collagen catabolic process Biological process 11408482 FRRS1 391059 ferric-chelate reductase 1 oxidation-reduction process Biological process - ZYG11B 79699 zyg-11 family member B, cell cycle regulator Cul2-RING ubiquitin ligase complex Cellular component - PKLR 5313 pyruvate kinase, liver and RBC response to lithium ion Biological process - HIST1H4E 8367 histone cluster 1, H4e protein binding Molecular function 10220385 SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) cysteine-type endopeptidase inhibitor activity involved in apoptotic process Molecular function 10818098 DMC1 11144 DNA meiotic recombinase 1 oocyte maturation Biological process - ESR1 2099 estrogen receptor 1 negative regulation of I-kappaB kinase/NF-kappaB signaling Biological process 16043358 GLRB 2743 glycine receptor, beta startle response Biological process 11929858 BTBD1 53339 BTB (POZ) domain containing 1 protein ubiquitination Biological process - HCFC1 3054 host cell factor C1 release from viral latency Biological process 10675337 AQP5 362 aquaporin 5 transmembrane transport Biological process - MAPKAPK5 8550 mitogen-activated protein kinase-activated protein kinase 5 cell surface receptor signaling pathway Biological process - RNF175 285533 ring finger protein 175 protein ubiquitination Biological process - ALK 238 anaplastic lymphoma receptor tyrosine kinase protein complex Cellular component 23382219 UBIAD1 29914 UbiA prenyltransferase domain containing 1 protein binding Molecular function 23169578 ZNF606 80095 zinc finger protein 606 transcription, DNA-templated Biological process - MYC 4609 v-myc avian myelocytomatosis viral oncogene homolog MAPK cascade Biological process 17873522 ALX4 60529 ALX homeobox 4 HMG box domain binding Molecular function - OR2T27 403239 olfactory receptor, family 2, subfamily T, member 27 detection of chemical stimulus involved in sensory perception of smell Biological process - ESR1 2099 estrogen receptor 1 steroid binding Molecular function - ACVR2A 92 activin A receptor, type IIA protein binding Molecular function 10746731 BCL11B 64919 B-cell CLL/lymphoma 11B (zinc finger protein) olfactory bulb axon guidance Biological process - GTF2B 2959 general transcription factor IIB transcription from RNA polymerase II promoter Biological process - STEAP3 55240 STEAP family member 3, metalloreductase transmembrane transport Biological process - ADCY2 108 adenylate cyclase 2 (brain) G-protein beta/gamma-subunit complex binding Molecular function - CDC20 991 cell division cycle 20 small GTPase mediated signal transduction Biological process - PLEKHM2 23207 pleckstrin homology domain containing, family M (with RUN domain) member 2 kinesin binding Molecular function 15905402 PLEKHF1 79156 pleckstrin homology domain containing, family F (with FYVE domain) member 1 lysosomal membrane Cellular component 22115783 COL3A1 1281 collagen, type III, alpha 1 response to cytokine Biological process 16360482 TACR3 6870 tachykinin receptor 3 plasma membrane Cellular component - RPS28 6234 ribosomal protein S28 viral process Biological process - ZKSCAN2 342357 zinc finger with KRAB and SCAN domains 2 DNA binding Molecular function - LPPR1 54886 lipid phosphate phosphatase-related protein type 1 nervous system development Biological process - NR1H4 9971 nuclear receptor subfamily 1, group H, member 4 nucleoplasm Cellular component - UBQLN1 29979 ubiquilin 1 ER-associated ubiquitin-dependent protein catabolic process Biological process 19822669 TCF24 100129654 transcription factor 24 DNA binding Molecular function - CLEC6A 93978 C-type lectin domain family 6, member A positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process - NLK 51701 nemo-like kinase nucleus Cellular component - ITGB1 3688 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) axon extension Biological process - TULP1 7287 tubby like protein 1 visual perception Biological process 9462750 H1FOO 132243 H1 histone family, member O, oocyte-specific nucleosome assembly Biological process - CLDN16 10686 claudin 16 bicellular tight junction Cellular component - CHPF 79586 chondroitin polymerizing factor glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Molecular function - BGLAP 632 bone gamma-carboxyglutamate (gla) protein regulation of bone mineralization Biological process - BNIP1 662 BCL2/adenovirus E1B 19kDa interacting protein 1 intracellular membrane-bounded organelle Cellular component 7954800 PTHLH 5744 parathyroid hormone-like hormone surfactant homeostasis Biological process - ANAPC2 29882 anaphase promoting complex subunit 2 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - HKDC1 80201 hexokinase domain containing 1 mannokinase activity Molecular function - CSNK1D 1453 casein kinase 1, delta endocytosis Biological process - RBM23 55147 RNA binding motif protein 23 RNA binding Molecular function - SLC38A7 55238 solute carrier family 38, member 7 amino acid transmembrane transport Biological process - IL1RL1 9173 interleukin 1 receptor-like 1 negative regulation of T-helper 1 type immune response Biological process - EEF1A1 1915 eukaryotic translation elongation factor 1 alpha 1 cellular protein metabolic process Biological process - SHC4 399694 SHC (Src homology 2 domain containing) family, member 4 intracellular Cellular component - OR4C6 219432 olfactory receptor, family 4, subfamily C, member 6 plasma membrane Cellular component - APOO 79135 apolipoprotein O extracellular space Cellular component 22261194 ARV1 64801 ARV1 homolog (S. cerevisiae) regulation of plasma membrane sterol distribution Biological process - FLVCR1 28982 feline leukemia virus subgroup C cellular receptor 1 erythrocyte differentiation Biological process 23187127 EFNA1 1942 ephrin-A1 negative regulation of transcription from RNA polymerase II promoter Biological process - HMGN1 3150 high mobility group nucleosome binding domain 1 chromatin Cellular component - USP4 7375 ubiquitin specific peptidase 4 (proto-oncogene) identical protein binding Molecular function 22001210 KCNA6 3742 potassium channel, voltage gated shaker related subfamily A, member 6 potassium ion transport Biological process 2347305 CASP2 835 caspase 2, apoptosis-related cysteine peptidase ectopic germ cell programmed cell death Biological process - ATP5C1 509 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 poly(A) RNA binding Molecular function 22658674 HSP90AB2P 391634 heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene protein folding Biological process - DLC1 10395 DLC1 Rho GTPase activating protein regulation of actin cytoskeleton organization Biological process 17292327 OR4K1 79544 olfactory receptor, family 4, subfamily K, member 1 detection of chemical stimulus involved in sensory perception Biological process - EGFR 1956 epidermal growth factor receptor innate immune response Biological process - SIRT1 23411 sirtuin 1 PML body Cellular component 12006491 UROD 7389 uroporphyrinogen decarboxylase porphyrin-containing compound metabolic process Biological process - PAK2 5062 p21 protein (Cdc42/Rac)-activated kinase 2 signal transduction Biological process 7744004 PYCARD 29108 PYD and CARD domain containing positive regulation of interleukin-6 secretion Biological process 16982856 RHCG 51458 Rh family, C glycoprotein ammonium transport Biological process 11062476 SFRP4 6424 secreted frizzled-related protein 4 positive regulation of keratinocyte apoptotic process Biological process 18938133 CHRNA3 1136 cholinergic receptor, nicotinic, alpha 3 (neuronal) cell junction Cellular component - IST1 9798 increased sodium tolerance 1 homolog (yeast) Flemming body Cellular component 19129479 OPA3 80207 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) visual perception Biological process 15342707 RAB39A 54734 RAB39A, member RAS oncogene family GTPase activity Molecular function - MAGEA1 4100 melanoma antigen family A1 nucleus Cellular component 15316101 IKZF1 10320 IKAROS family zinc finger 1 (Ikaros) natural killer cell differentiation Biological process - ATF5 22809 activating transcription factor 5 transcription factor complex Cellular component - C1QL1 10882 complement component 1, q subcomponent-like 1 locomotory behavior Biological process 9878755 PRKAA2 5563 protein kinase, AMP-activated, alpha 2 catalytic subunit cell cycle arrest Biological process - DDX20 11218 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 RNA processing Biological process 10601333 BIRC5 332 baculoviral IAP repeat containing 5 condensed chromosome kinetochore Cellular component 15665297 XPC 7508 xeroderma pigmentosum, complementation group C nucleus Cellular component - PDIA6 10130 protein disulfide isomerase family A, member 6 protein binding Molecular function 15466936 CYP26C1 340665 cytochrome P450, family 26, subfamily C, polypeptide 1 neural crest cell development Biological process - MPDZ 8777 multiple PDZ domain protein cytoplasmic vesicle Cellular component - TNNC1 7134 troponin C type 1 (slow) cytosol Cellular component - NFKBIA 4792 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha MyD88-dependent toll-like receptor signaling pathway Biological process - LRRTM4 80059 leucine rich repeat transmembrane neuronal 4 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex Cellular component - ACVR1B 91 activin A receptor, type IB activin receptor complex Cellular component 12665502 EFEMP1 2202 EGF containing fibulin-like extracellular matrix protein 1 extracellular matrix Cellular component 20551380 NELL1 4745 NEL-like 1 (chicken) regulation of gene expression Biological process 21723284 MTERF4 130916 mitochondrial transcription termination factor 4 regulation of transcription, DNA-templated Biological process - BLOC1S1 2647 biogenesis of lysosomal organelles complex-1, subunit 1 melanosome organization Biological process 15102850 JUP 3728 junction plakoglobin cytoskeletal anchoring at plasma membrane Biological process 22889254 FCGR3A 2214 Fc fragment of IgG, low affinity IIIa, receptor (CD16a) immune response Biological process 2138330 TBX4 9496 T-box 4 lung development Biological process - ERP29 10961 endoplasmic reticulum protein 29 positive regulation of gene expression Biological process 22064321 ZNF165 7718 zinc finger protein 165 transcription, DNA-templated Biological process - SLC29A3 55315 solute carrier family 29 (equilibrative nucleoside transporter), member 3 nucleoside transmembrane transport Biological process - GJA10 84694 gap junction protein, alpha 10, 62kDa plasma membrane Cellular component - CASP12 100506742 caspase 12 (gene/pseudogene) IPAF inflammasome complex Cellular component - ZNF594 84622 zinc finger protein 594 transcription, DNA-templated Biological process - STX10 8677 syntaxin 10 vesicle fusion Biological process - H2AFX 3014 H2A histone family, member X double-strand break repair via homologous recombination Biological process - ST8SIA6 338596 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 ganglioside biosynthetic process Biological process 11980897 DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) negative regulation of protein localization to plasma membrane Biological process 19581412 ZBTB42 100128927 zinc finger and BTB domain containing 42 cytoplasm Cellular component - TNIK 23043 TRAF2 and NCK interacting kinase protein serine/threonine kinase activity Molecular function 10521462 NTSR1 4923 neurotensin receptor 1 (high affinity) integral component of plasma membrane Cellular component 8381365 PARK7 11315 parkinson protein 7 positive regulation of protein homodimerization activity Biological process 24947010 OSR1 130497 odd-skipped related transciption factor 1 nucleic acid binding Molecular function - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa embryonic foregut morphogenesis Biological process - SUMO1 7341 small ubiquitin-like modifier 1 negative regulation of DNA binding Biological process 15637059 PTPN22 26191 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) perinuclear region of cytoplasm Cellular component 10068674 OAZ3 51686 ornithine decarboxylase antizyme 3 regulation of cellular amino acid metabolic process Biological process - APOA1BP 128240 apolipoprotein A-I binding protein NADHX epimerase activity Molecular function - POU3F3 5455 POU class 3 homeobox 3 metanephric loop of Henle development Biological process - PAK7 57144 p21 protein (Cdc42/Rac)-activated kinase 7 learning Biological process - ADRB1 153 adrenoceptor beta 1 lipid homeostasis Biological process - MTF1 4520 metal-regulatory transcription factor 1 nucleoplasm Cellular component - AGPAT5 55326 1-acylglycerol-3-phosphate O-acyltransferase 5 small molecule metabolic process Biological process - NEU4 129807 sialidase 4 sphingolipid metabolic process Biological process - RPSA 3921 ribosomal protein SA viral life cycle Biological process - BGN 633 biglycan Golgi lumen Cellular component - SDC3 9672 syndecan 3 phototransduction, visible light Biological process - PRICKLE4 29964 prickle homolog 4 (Drosophila) zinc ion binding Molecular function - PDCD10 11235 programmed cell death 10 stress fiber assembly Biological process 20332113 LPP 4026 LIM domain containing preferred translocation partner in lipoma zinc ion binding Molecular function - PSMD14 10213 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 cellular nitrogen compound metabolic process Biological process - ZACN 353174 zinc activated ligand-gated ion channel zinc ion binding Molecular function 12381728 GTF2E2 2961 general transcription factor IIE, polypeptide 2, beta 34kDa transcription factor TFIIE complex Cellular component - ATP6V0E1 8992 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 response to amino acid Biological process - YWHAH 7533 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta cytoplasmic vesicle membrane Cellular component - ENTPD5 957 ectonucleoside triphosphate diphosphohydrolase 5 cell proliferation Biological process - HCN4 10021 hyperpolarization activated cyclic nucleotide gated potassium channel 4 terminal bouton Cellular component - HCST 10870 hematopoietic cell signal transducer plasma membrane Cellular component - TLR8 51311 toll-like receptor 8 double-stranded RNA binding Molecular function 16111635 KIF27 55582 kinesin family member 27 ATP binding Molecular function - SEC14L2 23541 SEC14-like 2 (S. cerevisiae) transport Biological process - ADGRF2 222611 adhesion G protein-coupled receptor F2 G-protein coupled receptor activity Molecular function - RBFOX2 23543 RNA binding protein, fox-1 homolog (C. elegans) 2 regulation of alternative mRNA splicing, via spliceosome Biological process - JUND 3727 jun D proto-oncogene enzyme binding Molecular function 23382074 PARK7 11315 parkinson protein 7 glycolate biosynthetic process Biological process 22523093 RPA2 6118 replication protein A2, 32kDa nucleotide-excision repair, DNA damage removal Biological process - SRXN1 140809 sulfiredoxin 1 sulfiredoxin activity Molecular function - PRKCE 5581 protein kinase C, epsilon mitochondrion Cellular component - HDAC10 83933 histone deacetylase 10 negative regulation of transcription, DNA-templated Biological process 11726666 ARHGEF6 9459 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 protein binding Molecular function 11864573 CYFIP1 23191 cytoplasmic FMR1 interacting protein 1 SCAR complex Cellular component 21107423 NANOS3 342977 nanos homolog 3 (Drosophila) negative regulation of translation Biological process 24736845 SLC30A6 55676 solute carrier family 30 (zinc transporter), member 6 Golgi to endosome transport Biological process - ZNF780A 284323 zinc finger protein 780A regulation of transcription, DNA-templated Biological process - SETMAR 6419 SET domain and mariner transposase fusion gene replication fork processing Biological process 20457750 ENPP5 59084 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) metal ion binding Molecular function - IFIT2 3433 interferon-induced protein with tetratricopeptide repeats 2 cytosol Cellular component - GNG2 54331 guanine nucleotide binding protein (G protein), gamma 2 cell proliferation Biological process - CCNE1 898 cyclin E1 mitotic cell cycle Biological process - NCAPG 64151 non-SMC condensin I complex, subunit G condensin complex Cellular component 11136719 HTR2B 3357 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled cardiac muscle hypertrophy Biological process - PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 filamentous actin Cellular component 9395435 CDK11B 984 cyclin-dependent kinase 11B regulation of cell growth Biological process 10882096 SCN5A 6331 sodium channel, voltage gated, type V alpha subunit ventricular cardiac muscle cell action potential Biological process 18065446 ICOSLG 23308 inducible T-cell co-stimulator ligand plasma membrane Cellular component - SIRT2 22933 sirtuin 2 negative regulation of fat cell differentiation Biological process - NCOA1 8648 nuclear receptor coactivator 1 nucleoplasm Cellular component - PKD2 5311 polycystic kidney disease 2 (autosomal dominant) heart development Biological process 11891195 STXBP2 6813 syntaxin binding protein 2 specific granule Cellular component 18588921 SETD8 387893 SET domain containing (lysine methyltransferase) 8 histone lysine methylation Biological process - GRK5 2869 G protein-coupled receptor kinase 5 focal adhesion Cellular component - ANXA9 8416 annexin A9 synaptic transmission Biological process 10899159 SGPP1 81537 sphingosine-1-phosphate phosphatase 1 extrinsic apoptotic signaling pathway Biological process - LIM2 3982 lens intrinsic membrane protein 2, 19kDa lens development in camera-type eye Biological process - GNL3L 54552 guanine nucleotide binding protein-like 3 (nucleolar)-like protein binding Molecular function 21132010 CXCL12 6387 chemokine (C-X-C motif) ligand 12 cell adhesion Biological process 10198043 SOX7 83595 SRY (sex determining region Y)-box 7 sequence-specific DNA binding Molecular function - SOX3 6658 SRY (sex determining region Y)-box 3 negative regulation of neuron differentiation Biological process - NME5 8382 NME/NM23 family member 5 nucleoside metabolic process Biological process 9742940 ADPRHL2 54936 ADP-ribosylhydrolase like 2 nucleoplasm Cellular component - RAMP2 10266 receptor (G protein-coupled) activity modifying protein 2 heart development Biological process - APOA4 337 apolipoprotein A-IV neuron projection regeneration Biological process - NLRP1 22861 NLR family, pyrin domain containing 1 NLRP1 inflammasome complex Cellular component 20303873 RAB35 11021 RAB35, member RAS oncogene family endocytic recycling Biological process - ICAM5 7087 intercellular adhesion molecule 5, telencephalin plasma membrane Cellular component 8995416 EGFR 1956 epidermal growth factor receptor magnesium ion homeostasis Biological process - SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 manganese ion transmembrane transport Biological process - EDN3 1908 endothelin 3 intracellular Cellular component 1917960 PGAM1 5223 phosphoglycerate mutase 1 (brain) gluconeogenesis Biological process - C5AR1 728 complement component 5a receptor 1 activation of phospholipase C activity Biological process 7649993 CLTA 1211 clathrin, light chain A clathrin-coated endocytic vesicle membrane Cellular component - ABCB10 23456 ATP-binding cassette, sub-family B (MDR/TAP), member 10 metabolic process Biological process - AQP6 363 aquaporin 6, kidney specific transport Biological process 8812490 PTPN22 26191 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) protein tyrosine phosphatase activity Molecular function 10068674 SMARCA2 6595 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 histone binding Molecular function - TBX19 9095 T-box 19 anatomical structure morphogenesis Biological process 9888994 MOS 4342 v-mos Moloney murine sarcoma viral oncogene homolog establishment of meiotic spindle orientation Biological process - LTB4R 1241 leukotriene B4 receptor plasma membrane Cellular component - ANXA2 302 annexin A2 Rab GTPase binding Molecular function - FOXD4 2298 forkhead box D4 transcription from RNA polymerase II promoter Biological process - FGF1 2246 fibroblast growth factor 1 (acidic) insulin receptor signaling pathway Biological process - RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region epithelial to mesenchymal transition Biological process - MECP2 4204 methyl CpG binding protein 2 post-embryonic development Biological process - DPEP1 1800 dipeptidase 1 (renal) cysteine-type endopeptidase inhibitor activity involved in apoptotic process Molecular function 20435919 TYMS 7298 thymidylate synthetase pyrimidine nucleobase metabolic process Biological process - RNF4 6047 ring finger protein 4 sequence-specific DNA binding transcription factor activity Molecular function 9710597 CYP1A2 1544 cytochrome P450, family 1, subfamily A, polypeptide 2 oxidative demethylation Biological process 18619574 ALOX15B 247 arachidonate 15-lipoxygenase, type B iron ion binding Molecular function 24497644 RABEP1 9135 rabaptin, RAB GTPase binding effector protein 1 positive regulation of GTPase activity Biological process - APTX 54840 aprataxin phosphoglycolate phosphatase activity Molecular function 17519253 MEF2C 4208 myocyte enhancer factor 2C glomerulus morphogenesis Biological process - EWSR1 2130 EWS RNA-binding protein 1 protein binding Molecular function 16189514 RBM15B 29890 RNA binding motif protein 15B poly(A) RNA binding Molecular function 22658674 AGPAT1 10554 1-acylglycerol-3-phosphate O-acyltransferase 1 positive regulation of cellular metabolic process Biological process - RYR3 6263 ryanodine receptor 3 protein homotetramerization Biological process - SLC38A2 54407 solute carrier family 38, member 2 neurotransmitter secretion Biological process - SLA 6503 Src-like-adaptor endosome Cellular component - CPSF3 51692 cleavage and polyadenylation specific factor 3, 73kDa mRNA cleavage and polyadenylation specificity factor complex Cellular component 18305108 SPTBN1 6711 spectrin, beta, non-erythrocytic 1 phospholipid binding Molecular function - ST6GALNAC6 30815 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 dolichol-linked oligosaccharide biosynthetic process Biological process - GNAI1 2770 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Biological process - ACACA 31 acetyl-CoA carboxylase alpha triglyceride biosynthetic process Biological process - EIF4A3 9775 eukaryotic translation initiation factor 4A3 RNA splicing Biological process - LAMTOR1 55004 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 extracellular exosome Cellular component 19056867 CHST11 50515 carbohydrate (chondroitin 4) sulfotransferase 11 small molecule metabolic process Biological process - PCM1 5108 pericentriolar material 1 cytoplasmic microtubule organization Biological process 22797915 ATP1B1 481 ATPase, Na+/K+ transporting, beta 1 polypeptide ATPase activator activity Molecular function 10636900 FST 10468 follistatin cytoplasm Cellular component - SERPINE3 647174 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 extracellular space Cellular component - RQCD1 9125 RCD1 required for cell differentiation1 homolog (S. pombe) protein binding Molecular function 18180299 STAR 6770 steroidogenic acute regulatory protein fractalkine metabolic process Biological process - DTL 51514 denticleless E3 ubiquitin protein ligase homolog (Drosophila) chromosome Cellular component - RASA1 5921 RAS p21 protein activator (GTPase activating protein) 1 protein binding Molecular function 1314164 HHEX 3087 hematopoietically expressed homeobox positive regulation of transcription from RNA polymerase II promoter Biological process 12655000 RHBDF2 79651 rhomboid 5 homolog 2 (Drosophila) endoplasmic reticulum membrane Cellular component - UQCRC1 7384 ubiquinol-cytochrome c reductase core protein I metal ion binding Molecular function - C5 727 complement component 5 chemotaxis Biological process 10820279 MAPK6 5597 mitogen-activated protein kinase 6 cytoplasm Cellular component - BRI3BP 140707 BRI3 binding protein integral component of membrane Cellular component - F10 2159 coagulation factor X calcium ion binding Molecular function - CCL5 6352 chemokine (C-C motif) ligand 5 positive regulation of viral genome replication Biological process 10488085 RRP1B 23076 ribosomal RNA processing 1B cytosol Cellular component 16780588 XIAP 331 X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase regulation of nucleotide-binding oligomerization domain containing signaling pathway Biological process 20888210 PRRG4 79056 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) integral component of membrane Cellular component 11171957 SGK1 6446 serum/glucocorticoid regulated kinase 1 regulation of catalytic activity Biological process 20530112 NR1H2 7376 nuclear receptor subfamily 1, group H, member 2 positive regulation of pancreatic juice secretion Biological process - RANBP2 5903 RAN binding protein 2 post-translational protein modification Biological process - TNFSF15 9966 tumor necrosis factor (ligand) superfamily, member 15 activation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 11911831 THY1 7070 Thy-1 cell surface antigen T cell receptor signaling pathway Biological process - PRPH 5630 peripherin neurofilament Cellular component - ZNF239 8187 zinc finger protein 239 transcription, DNA-templated Biological process - EDNRB 1910 endothelin receptor type B positive regulation of penile erection Biological process - TWIST1 7291 twist family bHLH transcription factor 1 cardiac neural crest cell migration involved in outflow tract morphogenesis Biological process - MYO5A 4644 myosin VA (heavy chain 12, myoxin) peroxisome Cellular component 24006491 CIRBP 1153 cold inducible RNA binding protein nucleus Cellular component - NLGN4Y 22829 neuroligin 4, Y-linked vocalization behavior Biological process 18628683 NSF 4905 N-ethylmaleimide-sensitive factor plasma membrane Cellular component 15613468 EMILIN2 84034 elastin microfibril interfacer 2 cell adhesion Biological process - WASF2 10163 WAS protein family, member 2 SCAR complex Cellular component 21107423 MEN1 4221 multiple endocrine neoplasia I negative regulation of cyclin-dependent protein serine/threonine kinase activity Biological process 15640349 KRTAP2-4 85294 keratin associated protein 2-4 keratin filament Cellular component - MYH14 79784 myosin, heavy chain 14, non-muscle skeletal muscle contraction Biological process 21480433 RASAL1 8437 RAS protein activator like 1 (GAP1 like) cytosol Cellular component 16009725 ITPKA 3706 inositol-trisphosphate 3-kinase A protein phosphorylation Biological process - CDKN1A 1026 cyclin-dependent kinase inhibitor 1A (p21, Cip1) negative regulation of apoptotic process Biological process - UGT1A8 54576 UDP glucuronosyltransferase 1 family, polypeptide A8 protein heterodimerization activity Molecular function 20610558 ZNF711 7552 zinc finger protein 711 protein binding Molecular function 20346720 CACNA1I 8911 calcium channel, voltage-dependent, T type, alpha 1I subunit low voltage-gated calcium channel activity Molecular function - PSMB5 5693 proteasome (prosome, macropain) subunit, beta type, 5 cytosol Cellular component - CCND1 595 cyclin D1 positive regulation of G2/M transition of mitotic cell cycle Biological process 19124461 STK25 10494 serine/threonine kinase 25 protein phosphorylation Biological process 17657516 TIMP4 7079 TIMP metallopeptidase inhibitor 4 biological_process Biological process - RNASE12 493901 ribonuclease, RNase A family, 12 (non-active) nucleic acid binding Molecular function - MFI2 4241 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 positive regulation of extracellular matrix disassembly Biological process 16713448 YBEY 54059 ybeY metallopeptidase (putative) rRNA processing Biological process - KLHL3 26249 kelch-like family member 3 structural molecule activity Molecular function 10843806 HP1BP3 50809 heterochromatin protein 1, binding protein 3 regulation of nucleus size Biological process 24830416 GART 2618 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase tetrahydrofolate biosynthetic process Biological process - SRSF2 6427 serine/arginine-rich splicing factor 2 transcription corepressor activity Molecular function 15652350 CEL 1056 carboxyl ester lipase hydrolase activity Molecular function 2265692 DHRS2 10202 dehydrogenase/reductase (SDR family) member 2 nuclear envelope Cellular component 11997086 RAB11FIP3 9727 RAB11 family interacting protein 3 (class II) vesicle-mediated transport Biological process 16148947 RBMS1 5937 RNA binding motif, single stranded interacting protein 1 protein binding Molecular function 10869558 PLK2 10769 polo-like kinase 2 G1/S transition of mitotic cell cycle Biological process 15242618 SLC31A1 1317 solute carrier family 31 (copper transporter), member 1 copper uptake transmembrane transporter activity Molecular function - KCNH1 3756 potassium channel, voltage gated eag related subfamily H, member 1 phosphorelay sensor kinase activity Molecular function - RHOH 399 ras homolog family member H regulation of transcription, DNA-templated Biological process 11809807 WAS 7454 Wiskott-Aldrich syndrome epidermis development Biological process 8069912 PRKCG 5582 protein kinase C, gamma synaptic transmission Biological process - KRAS 3845 Kirsten rat sarcoma viral oncogene homolog fibroblast growth factor receptor signaling pathway Biological process - IGFBP4 3487 insulin-like growth factor binding protein 4 type B pancreatic cell proliferation Biological process - FRS2 10818 fibroblast growth factor receptor substrate 2 ventricular septum development Biological process - CPEB4 80315 cytoplasmic polyadenylation element binding protein 4 postsynaptic density Cellular component - GDNF 2668 glial cell derived neurotrophic factor protein binding Molecular function 25416956 PEX19 5824 peroxisomal biogenesis factor 19 integral component of membrane Cellular component 10051604 MSH2 4436 mutS homolog 2 somatic hypermutation of immunoglobulin genes Biological process - PEX7 5191 peroxisomal biogenesis factor 7 enzyme binding Molecular function 11931631 WNT2 7472 wingless-type MMTV integration site family member 2 positive regulation of fibroblast proliferation Biological process 19734317 IGSF6 10261 immunoglobulin superfamily, member 6 immune response Biological process 9809579 VAMP8 8673 vesicle-associated membrane protein 8 recycling endosome Cellular component 18570918 BDH1 622 3-hydroxybutyrate dehydrogenase, type 1 response to insulin Biological process - KLF10 7071 Kruppel-like factor 10 sequence-specific DNA binding transcription factor activity Molecular function 10816551 CHRNA4 1137 cholinergic receptor, nicotinic, alpha 4 (neuronal) response to hypoxia Biological process 12189247 LAMTOR1 55004 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 protein complex scaffold Molecular function 22980980 DTNBP1 84062 dystrobrevin binding protein 1 melanosome organization Biological process 22203680 SAR1B 51128 secretion associated, Ras related GTPase 1B protein N-linked glycosylation via asparagine Biological process - DFNB31 25861 deafness, autosomal recessive 31 protein binding Molecular function 17584769 CPOX 1371 coproporphyrinogen oxidase response to iron ion Biological process - ACADL 33 acyl-CoA dehydrogenase, long chain fatty acid beta-oxidation using acyl-CoA dehydrogenase Biological process - ATP6V1A 523 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A mitochondrion Cellular component - SLC25A17 10478 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 AMP transmembrane transporter activity Molecular function 22185573 AKIP1 56672 A kinase (PRKA) interacting protein 1 nucleoplasm Cellular component - HEXA 3073 hexosaminidase A (alpha polypeptide) keratan sulfate metabolic process Biological process - TNNT1 7138 troponin T type 1 (skeletal, slow) cytosol Cellular component - PACRGL 133015 PARK2 co-regulated-like protein binding Molecular function 25416956 GNB1 2782 guanine nucleotide binding protein (G protein), beta polypeptide 1 G-protein coupled acetylcholine receptor signaling pathway Biological process 8717044 DAB2IP 153090 DAB2 interacting protein negative regulation of MAP kinase activity Biological process 20154697 DCN 1634 decorin skeletal muscle tissue development Biological process - PSD 5662 pleckstrin and Sec7 domain containing ruffle Cellular component - HIST1H4C 8364 histone cluster 1, H4c DNA replication-independent nucleosome assembly Biological process 14718166 NPY5R 4889 neuropeptide Y receptor Y5 positive regulation of smooth muscle cell proliferation Biological process - ATP1A3 478 ATPase, Na+/K+ transporting, alpha 3 polypeptide adult locomotory behavior Biological process - ADCYAP1R1 117 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I neuropeptide binding Molecular function - GDNF 2668 glial cell derived neurotrophic factor regulation of morphogenesis of a branching structure Biological process - CYP2D6 1565 cytochrome P450, family 2, subfamily D, polypeptide 6 coumarin metabolic process Biological process 19438707 GLO1 2739 glyoxalase I carbohydrate metabolic process Biological process - PRKD1 5587 protein kinase D1 intracellular signal transduction Biological process 18059339 SRSF7 6432 serine/arginine-rich splicing factor 7 nucleotide binding Molecular function - CHCHD1 118487 coiled-coil-helix-coiled-coil-helix domain containing 1 poly(A) RNA binding Molecular function 22681889 TMEM39A 55254 transmembrane protein 39A integral component of membrane Cellular component - CELA3B 23436 chymotrypsin-like elastase family, member 3B peptidase activity Molecular function 2460440 ELOVL1 64834 ELOVL fatty acid elongase 1 protein binding Molecular function 20937905 METTL14 57721 methyltransferase like 14 nucleus Cellular component 24316715 ATF1 466 activating transcription factor 1 ATF1-ATF4 transcription factor complex Cellular component 12871976 ATP1A1 476 ATPase, Na+/K+ transporting, alpha 1 polypeptide protein domain specific binding Molecular function - RHOBTB3 22836 Rho-related BTB domain containing 3 small GTPase mediated signal transduction Biological process - CD46 4179 CD46 molecule, complement regulatory protein interleukin-10 production Biological process 23086448 STEAP4 79689 STEAP family member 4 extracellular exosome Cellular component 23533145 ARL3 403 ADP-ribosylation factor-like 3 GTPase activity Molecular function - PLG 5340 plasminogen blood microparticle Cellular component 22516433 RSPH1 89765 radial spoke head 1 homolog (Chlamydomonas) cytosol Cellular component 16780588 EGFR 1956 epidermal growth factor receptor learning or memory Biological process - GCK 2645 glucokinase (hexokinase 4) positive regulation of insulin secretion Biological process 8132752 POLR2D 5433 polymerase (RNA) II (DNA directed) polypeptide D 7-methylguanosine mRNA capping Biological process - MYH6 4624 myosin, heavy chain 6, cardiac muscle, alpha BMP signaling pathway Biological process - RNASEH2C 84153 ribonuclease H2, subunit C nucleus Cellular component - TAPBP 6892 TAP binding protein (tapasin) integral component of lumenal side of endoplasmic reticulum membrane Cellular component - MAGEA8 4107 melanoma antigen family A8 molecular_function Molecular function - SIRT1 23411 sirtuin 1 positive regulation of macroautophagy Biological process 18296641 PDE3A 5139 phosphodiesterase 3A, cGMP-inhibited lipid metabolic process Biological process 8921398 SCGB1A1 7356 secretoglobin, family 1A, member 1 (uteroglobin) female pregnancy Biological process 10587371 DAB2IP 153090 DAB2 interacting protein tube formation Biological process 19033661 ABL2 27 ABL proto-oncogene 2, non-receptor tyrosine kinase neuromuscular process controlling balance Biological process - BCL2L1 598 BCL2-like 1 release of cytochrome c from mitochondria Biological process 9843949 INS 3630 insulin negative regulation of NAD(P)H oxidase activity Biological process 11443198 CD34 947 CD34 molecule hemopoiesis Biological process 15969628 CDKN1A 1026 cyclin-dependent kinase inhibitor 1A (p21, Cip1) G2/M transition of mitotic cell cycle Biological process 17553787 REPIN1 29803 replication initiator 1 nuclear origin of replication recognition complex Cellular component 10606657 IFT52 51098 intraflagellar transport 52 ciliary tip Cellular component - PNPT1 87178 polyribonucleotide nucleotidyltransferase 1 mitochondrial mRNA polyadenylation Biological process 18083837 VPS18 57617 vacuolar protein sorting 18 homolog (S. cerevisiae) endosome organization Biological process 18799622 SLC9A1 6548 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 cell migration Biological process 17565280 ALX4 60529 ALX homeobox 4 transcription, DNA-templated Biological process - ANXA1 301 annexin A1 signal transduction Biological process 16130169 PNPLA4 8228 patatin-like phospholipase domain containing 4 molecular_function Molecular function - SH3PXD2B 285590 SH3 and PX domains 2B SH2 domain binding Molecular function - PLRG1 5356 pleiotropic regulator 1 signal transduction Biological process 9765207 TYR 7299 tyrosinase thymus development Biological process - ARL4A 10124 ADP-ribosylation factor-like 4A plasma membrane Cellular component 17398095 FGFR2 2263 fibroblast growth factor receptor 2 organ morphogenesis Biological process - ATP4B 496 ATPase, H+/K+ exchanging, beta polypeptide transmembrane transport Biological process - H2AFY2 55506 H2A histone family, member Y2 nuclear chromatin Cellular component 19734898 ZNF146 7705 zinc finger protein 146 nucleolus Cellular component - ZNF223 7766 zinc finger protein 223 metal ion binding Molecular function - TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta) magnesium ion homeostasis Biological process - OPLAH 26873 5-oxoprolinase (ATP-hydrolysing) glutathione derivative biosynthetic process Biological process - SMAD7 4092 SMAD family member 7 collagen binding Molecular function - SLC7A8 23428 solute carrier family 7 (amino acid transporter light chain, L system), member 8 toxin transporter activity Molecular function 12117417 UQCRQ 27089 ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa hypothalamus development Biological process - TEC 7006 tec protein tyrosine kinase non-membrane spanning protein tyrosine kinase activity Molecular function 10518561 NLRP12 91662 NLR family, pyrin domain containing 12 cellular response to cytokine stimulus Biological process - EDARADD 128178 EDAR-associated death domain hair follicle development Biological process - SOD2 6648 superoxide dismutase 2, mitochondrial negative regulation of neuron apoptotic process Biological process 17251466 TGIF1 7050 TGFB-induced factor homeobox 1 retina development in camera-type eye Biological process - RPS27A 6233 ribosomal protein S27a gene expression Biological process - FAM32A 26017 family with sequence similarity 32, member A biological_process Biological process - CLVS2 134829 clavesin 2 clathrin-coated endocytic vesicle membrane Cellular component - RAB17 64284 RAB17, member RAS oncogene family melanosome transport Biological process - INPP5K 51763 inositol polyphosphate-5-phosphatase K negative regulation of glucose transport Biological process 12556481 PRAMEF7 441871 PRAME family member 7 negative regulation of apoptotic process Biological process - MEF2A 4205 myocyte enhancer factor 2A toll-like receptor 5 signaling pathway Biological process - APOBEC1 339 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 negative regulation of methylation-dependent chromatin silencing Biological process - SFTPB 6439 surfactant protein B respiratory gaseous exchange Biological process - C3orf58 205428 chromosome 3 open reading frame 58 extracellular space Cellular component 23784961 CASP9 842 caspase 9, apoptosis-related cysteine peptidase intrinsic apoptotic signaling pathway in response to DNA damage Biological process 15657060 ADARB1 104 adenosine deaminase, RNA-specific, B1 RNA binding Molecular function 9111310 ASNS 440 asparagine synthetase (glutamine-hydrolyzing) cellular response to glucose starvation Biological process 10085239 RNF144A 9781 ring finger protein 144A Golgi apparatus Cellular component 10942595 LIPC 3990 lipase, hepatic cholesterol homeostasis Biological process 1883393 TOM1L2 146691 target of myb1-like 2 (chicken) protein kinase binding Molecular function 16479011 GAS6 2621 growth arrest-specific 6 negative regulation of renal albumin absorption Biological process - TRNAU1AP 54952 tRNA selenocysteine 1 associated protein 1 cytoplasm Cellular component - RAPGEF1 2889 Rap guanine nucleotide exchange factor (GEF) 1 Rap guanyl-nucleotide exchange factor activity Molecular function 21840392 TSPYL1 7259 TSPY-like 1 nucleolus Cellular component - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide neurotrophin TRK receptor signaling pathway Biological process - TACR1 6869 tachykinin receptor 1 regulation of smooth muscle cell proliferation Biological process - HS3ST4 9951 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity Molecular function 9988767 ASPG 374569 asparaginase 1-alkyl-2-acetylglycerophosphocholine esterase activity Molecular function - JUNB 3726 jun B proto-oncogene transforming growth factor beta receptor signaling pathway Biological process - PHF2 5253 PHD finger protein 2 nucleoplasm Cellular component - PAFAH1B1 5048 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) vesicle transport along microtubule Biological process 10729324 PRDM6 93166 PR domain containing 6 nucleus Cellular component - SYNE2 23224 spectrin repeat containing, nuclear envelope 2 cytoskeletal anchoring at nuclear membrane Biological process 18396275 ULK3 25989 unc-51 like kinase 3 cytosol Cellular component - GAR1 54433 GAR1 ribonucleoprotein nucleolus Cellular component - SGIP1 84251 SH3-domain GRB2-like (endophilin) interacting protein 1 clathrin-coated vesicle Cellular component - ERBB3 2065 erb-b2 receptor tyrosine kinase 3 endocardial cushion development Biological process - PDIA6 10130 protein disulfide isomerase family A, member 6 protein disulfide isomerase activity Molecular function - PECAM1 5175 platelet/endothelial cell adhesion molecule 1 glomerular endothelium development Biological process 17464107 MYDGF 56005 myeloid-derived growth factor positive regulation of angiogenesis Biological process 25581518 HDAC3 8841 histone deacetylase 3 histone H3-K9 modification Biological process - SLC2A5 6518 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 proton transport Biological process - SMPD2 6610 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) integral component of plasma membrane Cellular component 9520418 SETD1A 9739 SET domain containing 1A positive regulation of stem cell proliferation Biological process - STX7 8417 syntaxin 7 endocytic vesicle Cellular component 10564279 ESX1 80712 ESX homeobox 1 negative regulation of transcription from RNA polymerase II promoter Biological process 15897875 ATRX 546 alpha thalassemia/mental retardation syndrome X-linked Sertoli cell development Biological process - CD34 947 CD34 molecule negative regulation of cellular response to heat Biological process 17505307 NEU2 4759 sialidase 2 (cytosolic sialidase) exo-alpha-(2->3)-sialidase activity Molecular function 22228546 DDX58 23586 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 ruffle membrane Cellular component 19122199 IL4 3565 interleukin 4 regulation of proton transport Biological process - FMNL1 752 formin-like 1 membrane Cellular component 19946888 ACER2 340485 alkaline ceramidase 2 ceramidase activity Molecular function 16940153 OXGR1 27199 oxoglutarate (alpha-ketoglutarate) receptor 1 G-protein coupled receptor activity Molecular function - NUP43 348995 nucleoporin 43kDa small GTPase mediated signal transduction Biological process - SERPINA1 5265 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein binding Molecular function 11057674 EN2 2020 engrailed homeobox 2 neuron development Biological process - TDO2 6999 tryptophan 2,3-dioxygenase small molecule metabolic process Biological process - TWIST1 7291 twist family bHLH transcription factor 1 cranial suture morphogenesis Biological process 11001584 IFNA5 3442 interferon, alpha 5 innate immune response Biological process - ITPR3 3710 inositol 1,4,5-trisphosphate receptor, type 3 signal transduction Biological process - NMNAT1 64802 nicotinamide nucleotide adenylyltransferase 1 nicotinate-nucleotide adenylyltransferase activity Molecular function 16118205 UCN 7349 urocortin negative regulation of neuron death Biological process - ANXA5 308 annexin A5 response to organic substance Biological process - NR4A1 3164 nuclear receptor subfamily 4, group A, member 1 fibroblast growth factor receptor signaling pathway Biological process - FIGF 2277 c-fos induced growth factor (vascular endothelial growth factor D) extracellular space Cellular component - MGST3 4259 microsomal glutathione S-transferase 3 nuclear envelope Cellular component - KRTAP5-8 57830 keratin associated protein 5-8 keratin filament Cellular component - BLOC1S1 2647 biogenesis of lysosomal organelles complex-1, subunit 1 BLOC-1 complex Cellular component 15102850 CALCOCO1 57658 calcium binding and coiled-coil domain 1 intracellular membrane-bounded organelle Cellular component - GABRA1 2554 gamma-aminobutyric acid (GABA) A receptor, alpha 1 postsynaptic membrane Cellular component - TLR9 54106 toll-like receptor 9 I-kappaB phosphorylation Biological process 19740627 TNFAIP8L2 79626 tumor necrosis factor, alpha-induced protein 8-like 2 innate immune response Biological process - MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase cellular response to hydrogen peroxide Biological process - PSMB1 5689 proteasome (prosome, macropain) subunit, beta type, 1 programmed cell death Biological process - KAT6B 23522 K(lysine) acetyltransferase 6B histone acetylation Biological process 11965546 LITAF 9516 lipopolysaccharide-induced TNF factor transcription, DNA-templated Biological process - PINX1 54984 PIN2/TERF1 interacting, telomerase inhibitor 1 telomerase inhibitor activity Molecular function 15381700 GRIN2C 2905 glutamate receptor, ionotropic, N-methyl D-aspartate 2C N-methyl-D-aspartate selective glutamate receptor activity Molecular function - KCNJ11 3767 potassium channel, inwardly rectifying subfamily J, member 11 response to drug Biological process 18073297 MAN1A2 10905 mannosidase, alpha, class 1A, member 2 integral component of membrane Cellular component - OR4A15 81328 olfactory receptor, family 4, subfamily A, member 15 plasma membrane Cellular component - SLC43A3 29015 solute carrier family 43, member 3 cellular_component Cellular component - SAA1 6288 serum amyloid A1 negative regulation of inflammatory response Biological process 9823935 SMAD3 4088 SMAD family member 3 plasma membrane Cellular component - SYT11 23208 synaptotagmin XI synaptic vesicle exocytosis Biological process - LY96 23643 lymphocyte antigen 96 toll-like receptor 3 signaling pathway Biological process - CCL5 6352 chemokine (C-C motif) ligand 5 positive regulation of T cell proliferation Biological process 18832695 CDC7 8317 cell division cycle 7 protein binding Molecular function 12065429 SCN5A 6331 sodium channel, voltage gated, type V alpha subunit positive regulation of sodium ion transport Biological process 14500339 PMEPA1 56937 prostate transmembrane protein, androgen induced 1 androgen receptor signaling pathway Biological process 10873380 ARL11 115761 ADP-ribosylation factor-like 11 small GTPase mediated signal transduction Biological process - RAPGEF2 9693 Rap guanine nucleotide exchange factor (GEF) 2 blood vessel development Biological process - CIR1 9541 corepressor interacting with RBPJ, 1 nuclear speck Cellular component - RGS11 8786 regulator of G-protein signaling 11 termination of G-protein coupled receptor signaling pathway Biological process - SRI 6717 sorcin negative regulation of transcription regulatory region DNA binding Biological process - FARSB 10056 phenylalanyl-tRNA synthetase, beta subunit phenylalanyl-tRNA aminoacylation Biological process - UPF3B 65109 UPF3 regulator of nonsense transcripts homolog B (yeast) cytosol Cellular component - CDON 50937 cell adhesion associated, oncogene regulated positive regulation of muscle cell differentiation Biological process - TAF15 8148 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa protein binding Molecular function 19124016 SRPK1 6732 SRSF protein kinase 1 protein binding Molecular function 10196197 AGO3 192669 argonaute RISC catalytic component 3 miRNA loading onto RISC involved in gene silencing by miRNA Biological process 19966796 SCGB2A1 4246 secretoglobin, family 2A, member 1 extracellular space Cellular component 16395610 GPER1 2852 G protein-coupled estrogen receptor 1 neuronal action potential Biological process - RPL13AP3 645683 ribosomal protein L13a pseudogene 3 translation Biological process - OR10G2 26534 olfactory receptor, family 10, subfamily G, member 2 sensory perception of smell Biological process - EYA1 2138 EYA transcriptional coactivator and phosphatase 1 cellular protein localization Biological process - HNRNPF 3185 heterogeneous nuclear ribonucleoprotein F catalytic step 2 spliceosome Cellular component 11991638 BRIP1 83990 BRCA1 interacting protein C-terminal helicase 1 DNA duplex unwinding Biological process 11301010 RNASEL 6041 ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) cytosol Cellular component - ITPR1 3708 inositol 1,4,5-trisphosphate receptor, type 1 post-embryonic development Biological process - TNPO1 3842 transportin 1 protein import into nucleus, translocation Biological process 9144189 CLN8 2055 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) regulation of cell size Biological process - SMARCAD1 56916 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 positive regulation of transcription, DNA-templated Biological process 11031099 CASP2 835 caspase 2, apoptosis-related cysteine peptidase cytoplasm Cellular component - TRAM1 23471 translocation associated membrane protein 1 endoplasmic reticulum Cellular component 18555783 TADA2A 6871 transcriptional adaptor 2A nucleus Cellular component 8552087 CUL3 8452 cullin 3 stress fiber assembly Biological process 19782033 NOTCH1 4851 notch 1 calcium ion binding Molecular function - ABT1 29777 activator of basal transcription 1 nucleotide binding Molecular function - OR2M3 127062 olfactory receptor, family 2, subfamily M, member 3 G-protein coupled receptor activity Molecular function - FAT4 79633 FAT atypical cadherin 4 homophilic cell adhesion via plasma membrane adhesion molecules Biological process - MRPL15 29088 mitochondrial ribosomal protein L15 mitochondrial translational initiation Biological process - KMT2D 8085 lysine (K)-specific methyltransferase 2D histone methyltransferase complex Cellular component 14992727 ULK1 8408 unc-51 like autophagy activating kinase 1 response to starvation Biological process - MAOB 4129 monoamine oxidase B positive regulation of dopamine metabolic process Biological process - CSN2 1447 casein beta calcium ion binding Molecular function 2387396 SRR 63826 serine racemase serine racemase activity Molecular function 11054547 FOXA3 3171 forkhead box A3 spermatogenesis Biological process - FGF16 8823 fibroblast growth factor 16 intracellular Cellular component - WNT16 51384 wingless-type MMTV integration site family, member 16 proteinaceous extracellular matrix Cellular component - PSIP1 11168 PC4 and SFRS1 interacting protein 1 RNA polymerase II transcription coactivator activity Molecular function 9822615 ELP5 23587 elongator acetyltransferase complex subunit 5 regulation of transcription, DNA-templated Biological process - OR4A16 81327 olfactory receptor, family 4, subfamily A, member 16 integral component of membrane Cellular component - CA1 759 carbonic anhydrase I protein binding Molecular function 25416956 TUBB2B 347733 tubulin, beta 2B class IIb neuron migration Biological process 19465910 BRCA1 672 breast cancer 1, early onset regulation of DNA methylation Biological process - GIMAP5 55340 GTPase, IMAP family member 5 regulation of mitochondrial membrane permeability Biological process - RC3H1 149041 ring finger and CCCH-type domains 1 positive regulation of NIK/NF-kappaB signaling Biological process - APC2 10297 adenomatosis polyposis coli 2 negative regulation of canonical Wnt signaling pathway Biological process 10021369 LTF 4057 lactotransferrin positive regulation of protein serine/threonine kinase activity Biological process 20345905 HIPK2 28996 homeodomain interacting protein kinase 2 positive regulation of protein binding Biological process - RAB9B 51209 RAB9B, member RAS oncogene family intracellular protein transport Biological process - RSPO3 84870 R-spondin 3 frizzled binding Molecular function - GRIA4 2893 glutamate receptor, ionotropic, AMPA 4 synaptic transmission Biological process - THAP6 152815 THAP domain containing 6 DNA binding Molecular function - NKAIN2 154215 Na+/K+ transporting ATPase interacting 2 integral component of membrane Cellular component - RBMS1 5937 RNA binding motif, single stranded interacting protein 1 single-stranded DNA binding Molecular function 7838710 CRY1 1407 cryptochrome circadian clock 1 DNA repair Biological process - SDCBP 6386 syndecan binding protein (syntenin) protein C-terminus binding Molecular function - STXBP1 6812 syntaxin binding protein 1 axon target recognition Biological process - MYPN 84665 myopalladin muscle alpha-actinin binding Molecular function 11309420 STK39 27347 serine threonine kinase 39 cytoplasm Cellular component 10980603 GPR61 83873 G protein-coupled receptor 61 G-protein coupled receptor activity Molecular function - HCFC1 3054 host cell factor C1 MLL5-L complex Cellular component - MYLK 4638 myosin light chain kinase protein binding Molecular function 17474147 DFNB31 25861 deafness, autosomal recessive 31 stereocilia ankle link complex Cellular component - PPARA 5465 peroxisome proliferator-activated receptor alpha steroid hormone mediated signaling pathway Biological process - RBMXL1 494115 RNA binding motif protein, X-linked-like 1 mRNA processing Biological process - SAMD9L 219285 sterile alpha motif domain containing 9-like spleen development Biological process - AKR1A1 10327 aldo-keto reductase family 1, member A1 (aldehyde reductase) cytosol Cellular component - GCA 25801 grancalcin, EF-hand calcium binding protein protein binding Molecular function 25416956 PKP3 11187 plakophilin 3 desmosome Cellular component - PTH 5741 parathyroid hormone response to cadmium ion Biological process - DOCK9 23348 dedicator of cytokinesis 9 endomembrane system Cellular component - ADAMTS16 170690 ADAM metallopeptidase with thrombospondin type 1 motif, 16 proteolysis Biological process - TNK2 10188 tyrosine kinase, non-receptor, 2 adherens junction Cellular component - ERCC2 2068 excision repair cross-complementation group 2 spindle Cellular component 20797633 PKD2L2 27039 polycystic kidney disease 2-like 2 detection of mechanical stimulus Biological process - RPH3AL 9501 rabphilin 3A-like (without C2 domains) LIM domain binding Molecular function - ZNF180 7733 zinc finger protein 180 DNA binding Molecular function - FES 2242 FES proto-oncogene, tyrosine kinase protein autophosphorylation Biological process 7687763 ZXDC 79364 ZXD family zinc finger C positive regulation of transcription, DNA-templated Biological process 16600381 RAB14 51552 RAB14, member RAS oncogene family intracellular protein transport Biological process - ANO10 55129 anoctamin 10 membrane Cellular component 19946888 DYRK2 8445 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 ribonucleoprotein complex Cellular component - MYH9 4627 myosin, heavy chain 9, non-muscle negative regulation of actin filament severing Biological process - RAB27B 5874 RAB27B, member RAS oncogene family extracellular exosome Cellular component 19199708 VASN 114990 vasorin negative regulation of epithelial to mesenchymal transition Biological process 21170088 ERAP2 64167 endoplasmic reticulum aminopeptidase 2 zinc ion binding Molecular function 12799365 CD9 928 CD9 molecule external side of plasma membrane Cellular component - MARK1 4139 MAP/microtubule affinity-regulating kinase 1 microtubule cytoskeleton Cellular component 9108484 SCN9A 6335 sodium channel, voltage gated, type IX alpha subunit voltage-gated sodium channel activity Molecular function - INTU 27152 inturned planar cell polarity protein hair follicle morphogenesis Biological process - ADHFE1 137872 alcohol dehydrogenase, iron containing, 1 metal ion binding Molecular function - NDUFAF2 91942 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 mitochondrion Cellular component - PRKAR2A 5576 protein kinase, cAMP-dependent, regulatory, type II, alpha membrane Cellular component 19946888 ATP6V1F 9296 ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F ATPase activity, coupled to transmembrane movement of ions Molecular function - ENDOU 8909 endonuclease, polyU-specific immune response Biological process - ARL13B 200894 ADP-ribosylation factor-like 13B intracellular Cellular component - WDR47 22911 WD repeat domain 47 microtubule Cellular component - HLA-DPA1 3113 major histocompatibility complex, class II, DP alpha 1 ER to Golgi transport vesicle membrane Cellular component - ENTPD1 953 ectonucleoside triphosphate diphosphohydrolase 1 nucleoside-triphosphatase activity Molecular function - OR5K2 402135 olfactory receptor, family 5, subfamily K, member 2 plasma membrane Cellular component - GP1BA 2811 glycoprotein Ib (platelet), alpha polypeptide thrombin receptor activity Molecular function 12855810 OR7G3 390883 olfactory receptor, family 7, subfamily G, member 3 G-protein coupled receptor signaling pathway Biological process - GABARAP 11337 GABA(A) receptor-associated protein protein targeting Biological process 9892355 TNRC6C 57690 trinucleotide repeat containing 6C innate immune response Biological process - ARID4A 5926 AT rich interactive domain 4A (RBP1-like) transcription from RNA polymerase II promoter Biological process 8414517 TBPL1 9519 TBP-like 1 transcription coactivator activity Molecular function 10220372 TRA2B 6434 transformer 2 beta homolog (Drosophila) positive regulation of mRNA splicing, via spliceosome Biological process 15009664 SLC5A9 200010 solute carrier family 5 (sodium/sugar cotransporter), member 9 transporter activity Molecular function - GPC1 2817 glypican 1 glycosaminoglycan biosynthetic process Biological process - TGFB3 7043 transforming growth factor, beta 3 uterine wall breakdown Biological process 18039789 PIRT 644139 phosphoinositide-interacting regulator of transient receptor potential channels integral component of membrane Cellular component - ZC3H8 84524 zinc finger CCCH-type containing 8 negative regulation of transcription, DNA-templated Biological process - CNOT8 9337 CCR4-NOT transcription complex, subunit 8 intracellular Cellular component - TREM1 54210 triggering receptor expressed on myeloid cells 1 activation of mitophagy in response to mitochondrial depolarization Biological process 22020285 CNTNAP2 26047 contactin associated protein-like 2 axon Cellular component - GPD1L 23171 glycerol-3-phosphate dehydrogenase 1-like phosphatidic acid biosynthetic process Biological process - KDELR3 11015 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 integral component of membrane Cellular component - F7 2155 coagulation factor VII (serum prothrombin conversion accelerator) extracellular region Cellular component - CCRN4L 25819 CCR4 carbon catabolite repression 4-like (S. cerevisiae) response to extracellular stimulus Biological process - TUBB3 10381 tubulin, beta 3 class III 'de novo' posttranslational protein folding Biological process - PSMA6 5687 proteasome (prosome, macropain) subunit, alpha type, 6 programmed cell death Biological process - RHOBTB3 22836 Rho-related BTB domain containing 3 ATP binding Molecular function 19490898 MAPK8 5599 mitogen-activated protein kinase 8 apoptotic process Biological process - UGT1A4 54657 UDP glucuronosyltransferase 1 family, polypeptide A4 integral component of membrane Cellular component - FNTB 2342 farnesyltransferase, CAAX box, beta rhodopsin mediated signaling pathway Biological process - SERPINI1 5274 serpin peptidase inhibitor, clade I (neuroserpin), member 1 extracellular exosome Cellular component 23376485 RNF2 6045 ring finger protein 2 chromatin binding Molecular function 25519132 RFX8 731220 RFX family member 8, lacking RFX DNA binding domain nucleus Cellular component - TARS 6897 threonyl-tRNA synthetase protein homodimerization activity Molecular function 2033077 DCAF6 55827 DDB1 and CUL4 associated factor 6 focal adhesion Cellular component - ARTN 9048 artemin signal transduction Biological process 9883723 SHH 6469 sonic hedgehog embryonic limb morphogenesis Biological process - INTS7 25896 integrator complex subunit 7 chromosome Cellular component 21659603 OR4P4 81300 olfactory receptor, family 4, subfamily P, member 4 transmembrane signaling receptor activity Molecular function - G6PC 2538 glucose-6-phosphatase, catalytic subunit glycogen metabolic process Biological process 8211187 ATF7 11016 activating transcription factor 7 regulation of transcription, DNA-templated Biological process 8288576 BHMT 635 betaine--homocysteine S-methyltransferase small molecule metabolic process Biological process - LY9 4063 lymphocyte antigen 9 molecular_function Molecular function - LILRB2 10288 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 heterotypic cell-cell adhesion Biological process 19124746 GNA12 2768 guanine nucleotide binding protein (G protein) alpha 12 GTP binding Molecular function - SP6 80320 Sp6 transcription factor transcription, DNA-templated Biological process - LOXL4 84171 lysyl oxidase-like 4 protein-lysine 6-oxidase activity Molecular function - MBD1 4152 methyl-CpG binding domain protein 1 transcription from RNA polymerase II promoter Biological process 9774669 NSUN3 63899 NOP2/Sun domain family, member 3 methyltransferase activity Molecular function - TOMM5 401505 translocase of outer mitochondrial membrane 5 homolog (yeast) cellular protein metabolic process Biological process - MC2R 4158 melanocortin 2 receptor (adrenocorticotropic hormone) plasma membrane Cellular component - NET1 10276 neuroepithelial cell transforming 1 cytosol Cellular component - RAB9A 9367 RAB9A, member RAS oncogene family vacuolar membrane Cellular component - GJA1 2697 gap junction protein, alpha 1, 43kDa regulation of bicellular tight junction assembly Biological process - TWIST2 117581 twist family bHLH transcription factor 2 sequence-specific DNA binding transcription factor activity Molecular function - OR3A2 4995 olfactory receptor, family 3, subfamily A, member 2 receptor activity Molecular function 8921386 CYBA 1535 cytochrome b-245, alpha polypeptide innate immune response Biological process 2243141 CLECL1 160365 C-type lectin-like 1 plasma membrane Cellular component - ADCY3 109 adenylate cyclase 3 cellular response to glucagon stimulus Biological process - DEFB114 245928 defensin, beta 114 negative regulation of lipopolysaccharide-mediated signaling pathway Biological process 23482568 PARK2 5071 parkin RBR E3 ubiquitin protein ligase negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway Biological process 21113145 CXXC4 80319 CXXC finger protein 4 cytoplasm Cellular component 11113207 RAP1A 5906 RAP1A, member of RAS oncogene family protein transporter activity Molecular function 17916086 ME2 4200 malic enzyme 2, NAD(+)-dependent, mitochondrial oxidation-reduction process Biological process - EIF3K 27335 eukaryotic translation initiation factor 3, subunit K cytoplasm Cellular component - IL12RB2 3595 interleukin 12 receptor, beta 2 positive regulation of cell proliferation Biological process 8943050 THAP10 56906 THAP domain containing 10 protein binding Molecular function 21516116 HMGCR 3156 3-hydroxy-3-methylglutaryl-CoA reductase negative regulation of vasodilation Biological process - PLEKHG2 64857 pleckstrin homology domain containing, family G (with RhoGef domain) member 2 protein binding Molecular function 25416956 RHEB 6009 Ras homolog enriched in brain GTP binding Molecular function - TPR 7175 translocated promoter region, nuclear basket protein carbohydrate metabolic process Biological process - CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa cytosol Cellular component - EIF4G2 1982 eukaryotic translation initiation factor 4 gamma, 2 cytokine-mediated signaling pathway Biological process - STAT5B 6777 signal transducer and activator of transcription 5B cellular response to hormone stimulus Biological process 12552091 KCNE3 10008 potassium channel, voltage gated subfamily E regulatory beta subunit 3 regulation of membrane repolarization Biological process - RAP2B 5912 RAP2B, member of RAS oncogene family positive regulation of protein autophosphorylation Biological process - DYNLL2 140735 dynein, light chain, LC8-type 2 ciliary tip Cellular component - TPCN2 219931 two pore segment channel 2 protein binding Molecular function 21903581 CDC27 996 cell division cycle 27 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Biological process - HSPA2 3306 heat shock 70kDa protein 2 unfolded protein binding Molecular function 21231916 MEF2A 4205 myocyte enhancer factor 2A MyD88-dependent toll-like receptor signaling pathway Biological process - CNOT6 57472 CCR4-NOT transcription complex, subunit 6 positive regulation of cytoplasmic mRNA processing body assembly Biological process 21233283 MTMR2 8898 myotubularin related protein 2 negative regulation of receptor catabolic process Biological process - GAS2L1 10634 growth arrest-specific 2 like 1 regulation of cell cycle Biological process 19375645 ADCY7 113 adenylate cyclase 7 epidermal growth factor receptor signaling pathway Biological process - CTSL 1514 cathepsin L extracellular space Cellular component 22952693 SHPK 23729 sedoheptulokinase cellular response to interleukin-4 Biological process - TRIM37 4591 tripartite motif containing 37 tumor necrosis factor receptor binding Molecular function 11279055 BCHE 590 butyrylcholinesterase membrane Cellular component - CSTL1 128817 cystatin-like 1 extracellular region Cellular component - OR6N2 81442 olfactory receptor, family 6, subfamily N, member 2 detection of chemical stimulus involved in sensory perception of smell Biological process - FOXI3 344167 forkhead box I3 sequence-specific DNA binding transcription factor activity Molecular function - PSMB9 5698 proteasome (prosome, macropain) subunit, beta type, 9 antigen processing and presentation of peptide antigen via MHC class I Biological process - OR10AG1 282770 olfactory receptor, family 10, subfamily AG, member 1 G-protein coupled receptor activity Molecular function - KIF12 113220 kinesin family member 12 extracellular exosome Cellular component 19056867 KANK4 163782 KN motif and ankyrin repeat domains 4 cytoplasm Cellular component - PSEN2 5664 presenilin 2 protein complex Cellular component 9632714 PPM1N 147699 protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative) phosphoprotein phosphatase activity Molecular function - SHH 6469 sonic hedgehog negative regulation of cell migration Biological process - LOC400927-CSNK1E 102800317 LOC400927-CSNK1E readthrough protein binding Molecular function 11425858 GLUD1 2746 glutamate dehydrogenase 1 mitochondrial matrix Cellular component - RMDN3 55177 regulator of microtubule dynamics 3 mitochondrion Cellular component - SPRY2 10253 sprouty homolog 2 (Drosophila) positive regulation of ERK1 and ERK2 cascade Biological process 18070883 ADIRF 10974 adipogenesis regulatory factor molecular_function Molecular function - ST6GALNAC5 81849 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 protein N-linked glycosylation via asparagine Biological process - SYNM 23336 synemin, intermediate filament protein costamere Cellular component 16777071 ACVR1 90 activin A receptor, type I germ cell development Biological process - HNRNPM 4670 heterogeneous nuclear ribonucleoprotein M protein binding Molecular function 18457437 VKORC1L1 154807 vitamin K epoxide reductase complex, subunit 1-like 1 endoplasmic reticulum membrane Cellular component 21367861 PLK1 5347 polo-like kinase 1 activation of APC-Cdc20 complex activity Biological process 15148369 NDUFAF1 51103 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 mitochondrial electron transport, NADH to ubiquinone Biological process 11935339 CHRNG 1146 cholinergic receptor, nicotinic, gamma (muscle) transport Biological process 3967651 BAG5 9529 BCL2-associated athanogene 5 negative regulation of protein ubiquitination Biological process 15603737 CALM1 801 calmodulin 1 (phosphorylase kinase, delta) extracellular region Cellular component - PDK3 5165 pyruvate dehydrogenase kinase, isozyme 3 pyruvate metabolic process Biological process - RARG 5916 retinoic acid receptor, gamma regulation of cell size Biological process 18438858 FAM83D 81610 family with sequence similarity 83, member D mitotic nuclear division Biological process - CRHBP 1393 corticotropin releasing hormone binding protein synaptic transmission, dopaminergic Biological process - SUZ12 23512 SUZ12 polycomb repressive complex 2 subunit metal ion binding Molecular function - MTDH 92140 metadherin RNA polymerase II transcription factor binding Molecular function 18316612 RAB6B 51560 RAB6B, member RAS oncogene family retrograde transport, endosome to Golgi Biological process - RNF128 79589 ring finger protein 128, E3 ubiquitin protein ligase zinc ion binding Molecular function - RAC2 5880 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) lymphocyte aggregation Biological process 21167572 ZNF596 169270 zinc finger protein 596 metal ion binding Molecular function - NDUFC1 4717 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa small molecule metabolic process Biological process - GZMH 2999 granzyme H (cathepsin G-like 2, protein h-CCPX) serine-type endopeptidase activity Molecular function 2193684 RAPGEF2 9693 Rap guanine nucleotide exchange factor (GEF) 2 cellular response to cGMP Biological process 10801446 ABCB11 8647 ATP-binding cassette, sub-family B (MDR/TAP), member 11 bile acid and bile salt transport Biological process - FAM168B 130074 family with sequence similarity 168, member B perinuclear region of cytoplasm Cellular component - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide luteinization Biological process - PROCR 10544 protein C receptor, endothelial extracellular exosome Cellular component 23376485 GNG3 2785 guanine nucleotide binding protein (G protein), gamma 3 signal transducer activity Molecular function - MVB12B 89853 multivesicular body subunit 12B ubiquitin binding Molecular function 20654576 SI 6476 sucrase-isomaltase (alpha-glucosidase) plasma membrane Cellular component - UBE2D2 7322 ubiquitin-conjugating enzyme E2D 2 cytosol Cellular component - ZP4 57829 zona pellucida glycoprotein 4 positive regulation of protein kinase activity Biological process 18667750 HNRNPDL 9987 heterogeneous nuclear ribonucleoprotein D-like nucleoplasm Cellular component - QPCT 25797 glutaminyl-peptide cyclotransferase peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase Biological process 21288892 AP1S2 8905 adaptor-related protein complex 1, sigma 2 subunit cytosol Cellular component - LRRC29 26231 leucine rich repeat containing 29 protein binding Molecular function 25416956 CRH 1392 corticotropin releasing hormone response to ether Biological process - TYMP 1890 thymidine phosphorylase mitochondrial genome maintenance Biological process 9924029 AES 166 amino-terminal enhancer of split multicellular organismal development Biological process 8365415 ALB 213 albumin cellular response to starvation Biological process 16245148 GPR101 83550 G protein-coupled receptor 101 beta-adrenergic receptor activity Molecular function - TLR2 7097 toll-like receptor 2 response to insulin Biological process - TMEM219 124446 transmembrane protein 219 plasma membrane Cellular component - PHIP 55023 pleckstrin homology domain interacting protein negative regulation of apoptotic process Biological process - ADRBK1 156 adrenergic, beta, receptor kinase 1 fibroblast growth factor receptor signaling pathway Biological process - BCCIP 56647 BRCA2 and CDKN1A interacting protein kinase regulator activity Molecular function 10878006 ZNF74 7625 zinc finger protein 74 regulation of transcription, DNA-templated Biological process - ALOX15B 247 arachidonate 15-lipoxygenase, type B apoptotic process Biological process 11839751 FBP1 2203 fructose-1,6-bisphosphatase 1 glucose metabolic process Biological process - KIF21A 55605 kinesin family member 21A metabolic process Biological process - FUS 2521 FUS RNA binding protein identical protein binding Molecular function 23975937 PHAX 51808 phosphorylated adaptor for RNA export gene expression Biological process - CLNK 116449 cytokine-dependent hematopoietic cell linker protein binding Molecular function 16273093 SSR3 6747 signal sequence receptor, gamma (translocon-associated protein gamma) gene expression Biological process - ANTXR1 84168 anthrax toxin receptor 1 lamellipodium membrane Cellular component 16762926 RPS27A 6233 ribosomal protein S27a transforming growth factor beta receptor signaling pathway Biological process - UGT1A1 54658 UDP glucuronosyltransferase 1 family, polypeptide A1 steroid metabolic process Biological process 19996319 CORO1A 11151 coronin, actin binding protein, 1A membrane Cellular component 19946888 CCDC106 29903 coiled-coil domain containing 106 nucleoplasm Cellular component - KCNN2 3781 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 small conductance calcium-activated potassium channel activity Molecular function 10991935 RASGRP2 10235 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Ras protein signal transduction Biological process 10918068 PKM 5315 pyruvate kinase, muscle magnesium ion binding Molecular function - CTNNBL1 56259 catenin, beta like 1 nucleus Cellular component 12659813 PRKCQ 5588 protein kinase C, theta plasma membrane Cellular component - SCAF8 22828 SR-related CTD-associated factor 8 RNA binding Molecular function - NOS3 4846 nitric oxide synthase 3 (endothelial cell) endocytic vesicle membrane Cellular component - CTSB 1508 cathepsin B melanosome Cellular component - RGPD3 653489 RANBP2-like and GRIP domain containing 3 protein targeting to Golgi Biological process - PCSK1 5122 proprotein convertase subtilisin/kexin type 1 regulation of insulin secretion Biological process - ARSE 415 arylsulfatase E (chondrodysplasia punctata 1) sphingolipid metabolic process Biological process - AZU1 566 azurocidin 1 cytoplasm Cellular component - LRP4 4038 low density lipoprotein receptor-related protein 4 extracellular matrix organization Biological process - MED15 51586 mediator complex subunit 15 regulation of transcription from RNA polymerase II promoter Biological process - TLR2 7097 toll-like receptor 2 positive regulation of inflammatory response Biological process 19740627 ZNF354C 30832 zinc finger protein 354C nuclear membrane Cellular component - RAB3B 5865 RAB3B, member RAS oncogene family protein secretion Biological process - RNF4 6047 ring finger protein 4 protein K48-linked ubiquitination Biological process - AKR1C4 1109 aldo-keto reductase family 1, member C4 oxidation-reduction process Biological process - C21orf59 56683 chromosome 21 open reading frame 59 cytosol Cellular component 16780588 B4GALT1 2683 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 acute inflammatory response Biological process - KLC2 64837 kinesin light chain 2 kinesin I complex Cellular component 20510358 PPAP2A 8611 phosphatidic acid phosphatase type 2A phospholipid dephosphorylation Biological process 9468526 GNRH2 2797 gonadotropin-releasing hormone 2 extracellular region Cellular component - PIGP 51227 phosphatidylinositol glycan anchor biosynthesis, class P integral component of membrane Cellular component - NDFIP2 54602 Nedd4 family interacting protein 2 negative regulation of gene expression Biological process 18776082 NDRG3 57446 NDRG family member 3 negative regulation of cell growth Biological process 11406283 NF1 4763 neurofibromin 1 negative regulation of cell migration Biological process 16648142 LOXL1 4016 lysyl oxidase-like 1 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor Molecular function - CASP3 836 caspase 3, apoptosis-related cysteine peptidase extracellular matrix disassembly Biological process - OVCA2 124641 ovarian tumor suppressor candidate 2 metabolic process Biological process 11979432 VPS11 55823 vacuolar protein sorting 11 homolog (S. cerevisiae) nucleotide binding Molecular function - UPP2 151531 uridine phosphorylase 2 small molecule metabolic process Biological process - SNX30 401548 sorting nexin family member 30 protein binding Molecular function 23085988 VCAM1 7412 vascular cell adhesion molecule 1 viral process Biological process - IGF1 3479 insulin-like growth factor 1 (somatomedin C) platelet degranulation Biological process - MET 4233 MET proto-oncogene, receptor tyrosine kinase signal transduction Biological process 1846706 BCL2L11 10018 BCL2-like 11 (apoptosis facilitator) ear development Biological process - ACP5 54 acid phosphatase 5, tartrate resistant riboflavin metabolic process Biological process - TRABD2A 129293 TraB domain containing 2A head development Biological process - VPS35 55737 vacuolar protein sorting 35 homolog (S. cerevisiae) retromer complex Cellular component - CDH5 1003 cadherin 5, type 2 (vascular endothelium) calcium ion binding Molecular function - FSD1 79187 fibronectin type III and SPRY domain containing 1 cell division Biological process - IBTK 25998 inhibitor of Bruton agammaglobulinemia tyrosine kinase negative regulation of protein phosphorylation Biological process 11577348 CEBPZ 10153 CCAAT/enhancer binding protein (C/EBP), zeta poly(A) RNA binding Molecular function 22658674 TRAF6 7189 TNF receptor-associated factor 6, E3 ubiquitin protein ligase positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process - FLT4 2324 fms-related tyrosine kinase 4 sprouting angiogenesis Biological process - MICAL2 9645 microtubule associated monooxygenase, calponin and LIM domain containing 2 heart looping Biological process - ETV3 2117 ets variant 3 regulation of transcription from RNA polymerase II promoter Biological process - RBFOX2 23543 RNA binding protein, fox-1 homolog (C. elegans) 2 radial glia guided migration of Purkinje cell Biological process - MRPL44 65080 mitochondrial ribosomal protein L44 RNA processing Biological process - SIX2 10736 SIX homeobox 2 kidney development Biological process - FBXO4 26272 F-box protein 4 cytoplasm Cellular component - FOS 2353 FBJ murine osteosarcoma viral oncogene homolog transcription factor binding Molecular function 10523647 ARHGAP5 394 Rho GTPase activating protein 5 SH2 domain binding Molecular function 1689011 GNAT2 2780 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 photoreceptor outer segment membrane Cellular component - CHRNA4 1137 cholinergic receptor, nicotinic, alpha 4 (neuronal) respiratory gaseous exchange Biological process - YES1 7525 YES proto-oncogene 1, Src family tyrosine kinase protein binding Molecular function 15657067 OR10X1 128367 olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene) olfactory receptor activity Molecular function - MECP2 4204 methyl CpG binding protein 2 long-term synaptic potentiation Biological process - CDK18 5129 cyclin-dependent kinase 18 protein phosphorylation Biological process - CHP1 11261 calcineurin-like EF-hand protein 1 negative regulation of protein autophosphorylation Biological process - RPL14 9045 ribosomal protein L14 translation Biological process - TRIM43 129868 tripartite motif containing 43 protein binding Molecular function 25416956 PRSS16 10279 protease, serine, 16 (thymus) cytoplasmic membrane-bounded vesicle Cellular component - ABHD1 84696 abhydrolase domain containing 1 carboxylic ester hydrolase activity Molecular function - HSP90AB4P 664618 heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene response to stress Biological process - SMIM24 284422 small integral membrane protein 24 biological_process Biological process - B4GALNT2 124872 beta-1,4-N-acetyl-galactosaminyl transferase 2 protein glycosylation Biological process - STYX 6815 serine/threonine/tyrosine interacting protein protein binding Molecular function 23847209 RPLP2 6181 ribosomal protein, large, P2 extracellular exosome Cellular component 20458337 STX2 2054 syntaxin 2 basolateral plasma membrane Cellular component 16339081 MMRN2 79812 multimerin 2 negative regulation of vascular endothelial growth factor receptor signaling pathway Biological process 22020326 OR1L4 254973 olfactory receptor, family 1, subfamily L, member 4 detection of chemical stimulus involved in sensory perception of smell Biological process - SYNE1 23345 spectrin repeat containing, nuclear envelope 1 nucleoplasm Cellular component - SMN2 6607 survival of motor neuron 2, centromeric nucleus Cellular component 11283611 RGL2 5863 ral guanine nucleotide dissociation stimulator-like 2 Ral guanyl-nucleotide exchange factor activity Molecular function - ABCA7 10347 ATP-binding cassette, sub-family A (ABC1), member 7 endosome membrane Cellular component - LMAN2L 81562 lectin, mannose-binding 2-like protein transport Biological process 12878160 UBASH3A 53347 ubiquitin associated and SH3 domain containing A negative regulation of T cell receptor signaling pathway Biological process - VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor lithocholic acid receptor activity Molecular function 12016314 MYBL1 4603 v-myb avian myeloblastosis viral oncogene homolog-like 1 positive regulation of transcription from RNA polymerase II promoter Biological process 7987850 FAM53B 9679 family with sequence similarity 53, member B molecular_function Molecular function - CNR1 1268 cannabinoid receptor 1 (brain) negative regulation of nitric-oxide synthase activity Biological process - CALCOCO2 10241 calcium binding and coiled-coil domain 2 Golgi apparatus Cellular component - ANGPT4 51378 angiopoietin 4 positive regulation of blood vessel endothelial cell migration Biological process 15284220 HS3ST5 222537 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 heparan sulfate proteoglycan biosynthetic process, enzymatic modification Biological process 12138164 UGP2 7360 UDP-glucose pyrophosphorylase 2 UDP-glucose metabolic process Biological process - KIFC2 90990 kinesin family member C2 cytoplasm Cellular component - RHOU 58480 ras homolog family member U positive regulation of protein targeting to mitochondrion Biological process 24270810 PPP1R13L 10848 protein phosphatase 1, regulatory subunit 13 like intercellular bridge Cellular component - AZGP1 563 alpha-2-glycoprotein 1, zinc-binding immune response Biological process - NFS1 9054 NFS1 cysteine desulfurase metal ion binding Molecular function - TCTN2 79867 tectonic family member 2 cilium assembly Biological process - WDR61 80349 WD repeat domain 61 Cdc73/Paf1 complex Cellular component 20178742 GPC1 2817 glypican 1 anchored component of membrane Cellular component - SEC23IP 11196 SEC23 interacting protein intracellular membrane-bounded organelle Cellular component - TRDMT1 1787 tRNA aspartic acid methyltransferase 1 tRNA methyltransferase activity Molecular function 16424344 NRXN1 9378 neurexin 1 vocalization behavior Biological process 17034946 OR11H1 81061 olfactory receptor, family 11, subfamily H, member 1 G-protein coupled receptor signaling pathway Biological process - BLMH 642 bleomycin hydrolase carboxypeptidase activity Molecular function 9546396 CCL5 6352 chemokine (C-C motif) ligand 5 cellular calcium ion homeostasis Biological process 10734056 PGM3 5238 phosphoglucomutase 3 cytosol Cellular component - NTRK3 4916 neurotrophic tyrosine kinase, receptor, type 3 positive regulation of actin cytoskeleton reorganization Biological process 23027130 KIAA1109 84162 KIAA1109 protein binding Molecular function 20195357 CAD 790 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase small molecule metabolic process Biological process - WNT4 54361 wingless-type MMTV integration site family, member 4 negative regulation of gene expression Biological process 15317892 ARHGAP19 84986 Rho GTPase activating protein 19 small GTPase mediated signal transduction Biological process - SPTBN5 51332 spectrin, beta, non-erythrocytic 5 Golgi organization Biological process 23704327 PLEC 5339 plectin cytosol Cellular component - FGF4 2249 fibroblast growth factor 4 positive regulation of cell proliferation Biological process 8663044 MAN2A1 4124 mannosidase, alpha, class 2A, member 1 mitochondrion organization Biological process - RUNX2 860 runt-related transcription factor 2 endochondral ossification Biological process - SERP1 27230 stress-associated endoplasmic reticulum protein 1 cellular protein metabolic process Biological process - TPI1 7167 triosephosphate isomerase 1 ubiquitin protein ligase binding Molecular function 19725078 IGHD 3495 immunoglobulin heavy constant delta extracellular exosome Cellular component 23533145 SLC30A7 148867 solute carrier family 30 (zinc transporter), member 7 sequestering of zinc ion Biological process - DUSP9 1852 dual specificity phosphatase 9 cytoplasm Cellular component - HMGA2 8091 high mobility group AT-hook 2 negative regulation by host of viral transcription Biological process 17005673 CYP1A2 1544 cytochrome P450, family 1, subfamily A, polypeptide 2 intracellular membrane-bounded organelle Cellular component 2813353 RRAS2 22800 related RAS viral (r-ras) oncogene homolog 2 metabolic process Biological process 10777492 C4B 721 complement component 4B (Chido blood group) positive regulation of apoptotic cell clearance Biological process 19302245 ARPC5 10092 actin related protein 2/3 complex, subunit 5, 16kDa extracellular exosome Cellular component 19056867 TMEM108 66000 transmembrane protein 108 integral component of membrane Cellular component - HTR6 3362 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled serotonin receptor activity Molecular function - UBE2D1 7321 ubiquitin-conjugating enzyme E2D 1 mitotic spindle assembly checkpoint Biological process - NOS3 4846 nitric oxide synthase 3 (endothelial cell) mitochondrion organization Biological process - GDF3 9573 growth differentiation factor 3 notochord development Biological process - PRPH 5630 peripherin intermediate filament cytoskeleton organization Biological process - ENPP1 5167 ectonucleotide pyrophosphatase/phosphodiesterase 1 protein homodimerization activity Molecular function 7830796 ADM 133 adrenomedullin response to hypoxia Biological process - FFAR1 2864 free fatty acid receptor 1 G-protein coupled receptor activity Molecular function 9344866 GP2 2813 glycoprotein 2 (zymogen granule membrane) antigen binding Molecular function - POU4F2 5458 POU class 4 homeobox 2 chromatin binding Molecular function - GNA12 2768 guanine nucleotide binding protein (G protein) alpha 12 heterotrimeric G-protein complex Cellular component - PEX14 5195 peroxisomal biogenesis factor 14 integral component of membrane Cellular component - PLSCR1 5359 phospholipid scramblase 1 phospholipid scramblase activity Molecular function 10770950 ACE 1636 angiotensin I converting enzyme actin binding Molecular function 16186248 GABBR2 9568 gamma-aminobutyric acid (GABA) B receptor, 2 plasma membrane Cellular component - PTGIS 5740 prostaglandin I2 (prostacyclin) synthase icosanoid metabolic process Biological process - ADAR 103 adenosine deaminase, RNA-specific adenosine to inosine editing Biological process - ASF1B 55723 anti-silencing function 1B histone chaperone spermatogenesis Biological process - AQP1 358 aquaporin 1 (Colton blood group) protein binding Molecular function 16189514 CDCA8 55143 cell division cycle associated 8 nucleus Cellular component - ARNT 405 aryl hydrocarbon receptor nuclear translocator protein heterodimerization activity Molecular function 9079689 BNIP3 664 BCL2/adenovirus E1B 19kDa interacting protein 3 response to hypoxia Biological process - ZFP36L1 677 ZFP36 ring finger protein-like 1 regulation of transcription, DNA-templated Biological process 8595910 BSCL2 26580 Berardinelli-Seip congenital lipodystrophy 2 (seipin) lipid storage Biological process 19278620 TSC2 7249 tuberous sclerosis 2 protein transport into plasma membrane raft Biological process - TH 7054 tyrosine hydroxylase response to lipopolysaccharide Biological process - SERGEF 26297 secretion regulating guanine nucleotide exchange factor Ran guanyl-nucleotide exchange factor activity Molecular function 10571079 ALDH18A1 5832 aldehyde dehydrogenase 18 family, member A1 glutamate 5-kinase activity Molecular function 11092761 RBMS1 5937 RNA binding motif, single stranded interacting protein 1 nucleotide binding Molecular function - ABHD2 11057 abhydrolase domain containing 2 metabolic process Biological process - OR52Z1 283110 olfactory receptor, family 52, subfamily Z, member 1 (gene/pseudogene) detection of chemical stimulus involved in sensory perception of smell Biological process - USP6 9098 ubiquitin specific peptidase 6 calmodulin binding Molecular function 16127172 COL4A2 1284 collagen, type IV, alpha 2 extracellular region Cellular component - VAMP7 6845 vesicle-associated membrane protein 7 cell surface Cellular component - GATA4 2626 GATA binding protein 4 positive regulation of cardiac muscle cell proliferation Biological process - CXADR 1525 coxsackie virus and adenovirus receptor leukocyte migration Biological process - AGRN 375790 agrin neurotransmitter receptor metabolic process Biological process - AATK 9625 apoptosis-associated tyrosine kinase protein serine/threonine kinase activity Molecular function - APOA1 335 apolipoprotein A-I cholesterol homeostasis Biological process 15464323 PDPK1 5170 3-phosphoinositide dependent protein kinase 1 cytoplasmic membrane-bounded vesicle Cellular component - WFS1 7466 Wolfram syndrome 1 (wolframin) positive regulation of proteolysis Biological process - PDE11A 50940 phosphodiesterase 11A cGMP binding Molecular function 19689430 BOP1 23246 block of proliferation 1 preribosome, large subunit precursor Cellular component - ABCA6 23460 ATP-binding cassette, sub-family A (ABC1), member 6 ATPase activity, coupled to transmembrane movement of substances Molecular function - LGSN 51557 lengsin, lens protein with glutamine synthetase domain plasma membrane Cellular component - RNF141 50862 ring finger protein 141 ubiquitin-protein transferase activity Molecular function 24105792 SLC7A6 9057 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 transport Biological process 9829974 CNIH4 29097 cornichon family AMPA receptor auxiliary protein 4 CCR5 chemokine receptor binding Molecular function 24405750 IL17A 3605 interleukin 17A cell death Biological process 8390535 PRDX1 5052 peroxiredoxin 1 peroxisomal matrix Cellular component - MICB 4277 MHC class I polypeptide-related sequence B immune response-activating cell surface receptor signaling pathway Biological process 11491531 PDCD11 22984 programmed cell death 11 cytosol Cellular component - CMTM7 112616 CKLF-like MARVEL transmembrane domain containing 7 chemotaxis Biological process - PIN1 5300 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 regulation of mitotic nuclear division Biological process 10391244 CXCL10 3627 chemokine (C-X-C motif) ligand 10 CXCR3 chemokine receptor binding Molecular function 12782716 TGIF1 7050 TGFB-induced factor homeobox 1 negative regulation of transcription from RNA polymerase II promoter Biological process - BMP7 655 bone morphogenetic protein 7 positive regulation of pathway-restricted SMAD protein phosphorylation Biological process 11580864 ADGRV1 84059 adhesion G protein-coupled receptor V1 G-protein coupled receptor signaling pathway Biological process - ITGB4 3691 integrin, beta 4 filopodium assembly Biological process - ZDHHC3 51304 zinc finger, DHHC-type containing 3 protein targeting Biological process - FUBP1 8880 far upstream element (FUSE) binding protein 1 positive regulation of transcription from RNA polymerase II promoter Biological process - RUNX1 861 runt-related transcription factor 1 protein homodimerization activity Molecular function 10856244 GSK3B 2932 glycogen synthase kinase 3 beta cell migration Biological process - DST 667 dystonin focal adhesion Cellular component 21423176 TBX3 6926 T-box 3 negative regulation of myoblast differentiation Biological process 12032820 SREBF2 6721 sterol regulatory element binding transcription factor 2 E-box binding Molecular function 15358760 GNAL 2774 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type extracellular exosome Cellular component 23533145 ACVR1B 91 activin A receptor, type IB metal ion binding Molecular function - CACNA1C 775 calcium channel, voltage-dependent, L type, alpha 1C subunit regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion Biological process 11576544 CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa vascular endothelial growth factor receptor signaling pathway Biological process - FOLH1B 219595 folate hydrolase 1B proteolysis Biological process - HRH2 3274 histamine receptor H2 memory Biological process - SLC28A3 64078 solute carrier family 28 (concentrative nucleoside transporter), member 3 pyrimidine- and adenine-specific:sodium symporter activity Molecular function - NFIC 4782 nuclear factor I/C (CCAAT-binding transcription factor) odontogenesis of dentin-containing tooth Biological process - XRCC6 2547 X-ray repair complementing defective repair in Chinese hamster cells 6 double-strand break repair Biological process - LCK 3932 LCK proto-oncogene, Src family tyrosine kinase CD8 receptor binding Molecular function 2470098 RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 positive regulation of type I interferon production Biological process - APOH 350 apolipoprotein H (beta-2-glycoprotein I) extracellular matrix Cellular component 20551380 MRPL18 29074 mitochondrial ribosomal protein L18 mitochondrial translational termination Biological process - PPP6R3 55291 protein phosphatase 6, regulatory subunit 3 plasma membrane Cellular component - NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) adrenal gland development Biological process - RPS6KA1 6195 ribosomal protein S6 kinase, 90kDa, polypeptide 1 toll-like receptor 2 signaling pathway Biological process - GORAB 92344 golgin, RAB6-interacting Golgi apparatus Cellular component - TSG101 7251 tumor susceptibility 101 late endosome Cellular component 15126635 TENM3 55714 teneurin transmembrane protein 3 protein heterodimerization activity Molecular function - ZMAT3 64393 zinc finger, matrin-type 3 cellular response to DNA damage stimulus Biological process - DEPDC7 91614 DEP domain containing 7 molecular_function Molecular function - TRDMT1 1787 tRNA aspartic acid methyltransferase 1 tRNA methylation Biological process 16424344 MED20 9477 mediator complex subunit 20 DNA-directed RNA polymerase activity Molecular function 9933582 ATG101 60673 autophagy related 101 protein binding Molecular function 20562859 MYLK3 91807 myosin light chain kinase 3 calmodulin-dependent protein kinase activity Molecular function - TWIST1 7291 twist family bHLH transcription factor 1 nucleus Cellular component 10749989 GK2 2712 glycerol kinase 2 mitochondrial outer membrane Cellular component - IFNA13 3447 interferon, alpha 13 type I interferon signaling pathway Biological process - AGTPBP1 23287 ATP/GTP binding protein 1 protein side chain deglutamylation Biological process - FER1L4 80307 fer-1-like family member 4, pseudogene (functional) integral component of membrane Cellular component - IL23R 149233 interleukin 23 receptor positive regulation of granulocyte macrophage colony-stimulating factor production Biological process 20027291 PHKG1 5260 phosphorylase kinase, gamma 1 (muscle) glycogen biosynthetic process Biological process - ZYX 7791 zyxin plasma membrane Cellular component 8940160 WRAP53 55135 WD repeat containing, antisense to TP53 nucleus Cellular component - MARK2 2011 MAP/microtubule affinity-regulating kinase 2 protein autophosphorylation Biological process - PAQR8 85315 progestin and adipoQ receptor family member VIII response to steroid hormone Biological process - CA5BP1 340591 carbonic anhydrase VB pseudogene 1 carbonate dehydratase activity Molecular function - PNPO 55163 pyridoxamine 5'-phosphate oxidase cytoplasm Cellular component - BCAM 4059 basal cell adhesion molecule (Lutheran blood group) cell adhesion Biological process 7954395 SIX3 6496 SIX homeobox 3 transcription coactivator activity Molecular function - C4BPB 725 complement component 4 binding protein, beta negative regulation of complement activation, classical pathway Biological process 22333221 ATP6V0D2 245972 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 phagosome maturation Biological process - MUC5B 727897 mucin 5B, oligomeric mucus/gel-forming defense response to bacterium Biological process - TBX21 30009 T-box 21 sequence-specific DNA binding transcription factor activity Molecular function 10761931 TWF1 5756 twinfilin actin-binding protein 1 phosphatidylinositol-4,5-bisphosphate binding Molecular function 12807912 EDRF1 26098 erythroid differentiation regulatory factor 1 regulation of transcription, DNA-templated Biological process - RAB27B 5874 RAB27B, member RAS oncogene family protein domain specific binding Molecular function 16880209 RBL1 5933 retinoblastoma-like 1 positive regulation of transcription from RNA polymerase II promoter Biological process - TPR 7175 translocated promoter region, nuclear basket protein protein anchor Molecular function 12802065 ENG 2022 endoglin negative regulation of transforming growth factor beta receptor signaling pathway Biological process 11382917 GNAI2 2771 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 G-protein beta/gamma-subunit complex binding Molecular function - BAD 572 BCL2-associated agonist of cell death cellular response to lipid Biological process - RXRA 6256 retinoid X receptor, alpha regulation of branching involved in prostate gland morphogenesis Biological process - OR2A25 392138 olfactory receptor, family 2, subfamily A, member 25 olfactory receptor activity Molecular function - CHMP3 51652 charged multivesicular body protein 3 membrane organization Biological process - TMSB10 9168 thymosin beta 10 protein binding Molecular function 25416956 CTGF 1490 connective tissue growth factor cell-cell signaling Biological process - MYO6 4646 myosin VI motor activity Molecular function - NAT2 10 N-acetyltransferase 2 (arylamine N-acetyltransferase) arylamine N-acetyltransferase activity Molecular function - OR51Q1 390061 olfactory receptor, family 51, subfamily Q, member 1 (gene/pseudogene) detection of chemical stimulus involved in sensory perception of smell Biological process - SLC6A5 9152 solute carrier family 6 (neurotransmitter transporter), member 5 neurotransmitter:sodium symporter activity Molecular function - ICE2 79664 interactor of little elongation complex ELL subunit 2 transcriptionally active chromatin Cellular component 22195968 COL1A2 1278 collagen, type I, alpha 2 extracellular matrix organization Biological process - CD19 930 CD19 molecule epidermal growth factor receptor signaling pathway Biological process - A1BG 1 alpha-1-B glycoprotein extracellular exosome Cellular component 19056867 PTPN2 5771 protein tyrosine phosphatase, non-receptor type 2 regulation of interferon-gamma-mediated signaling pathway Biological process - STK11 6794 serine/threonine kinase 11 positive regulation of axonogenesis Biological process - LIPC 3990 lipase, hepatic high-density lipoprotein particle remodeling Biological process 3244012 ATP6V0A2 23545 ATPase, H+ transporting, lysosomal V0 subunit a2 ion transmembrane transport Biological process - SGK2 10110 serum/glucocorticoid regulated kinase 2 ion transmembrane transport Biological process - MKNK2 2872 MAP kinase interacting serine/threonine kinase 2 cellular response to arsenic-containing substance Biological process 18299328 PDE6A 5145 phosphodiesterase 6A, cGMP-specific, rod, alpha phototransduction, visible light Biological process - EXT1 2131 exostosin glycosyltransferase 1 olfactory bulb development Biological process - FCHO2 115548 FCH domain only 2 phosphatidylserine binding Molecular function - YTHDC2 64848 YTH domain containing 2 ATP-dependent RNA helicase activity Molecular function - XRCC2 7516 X-ray repair complementing defective repair in Chinese hamster cells 2 strand invasion Biological process 11834724 CAPZA3 93661 capping protein (actin filament) muscle Z-line, alpha 3 F-actin capping protein complex Cellular component - SOCS7 30837 suppressor of cytokine signaling 7 protein binding Molecular function 17803907 SLC6A17 388662 solute carrier family 6 (neutral amino acid transporter), member 17 neutral amino acid transport Biological process - ZNF570 148268 zinc finger protein 570 metal ion binding Molecular function - ABCB6 10058 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) endoplasmic reticulum Cellular component 22226084 RANBP10 57610 RAN binding protein 10 microtubule cytoskeleton organization Biological process - DCAF7 10238 DDB1 and CUL4 associated factor 7 cytoplasm Cellular component 9192870 CHMP4B 128866 charged multivesicular body protein 4B late endosome membrane Cellular component - UNK 85451 unkempt family zinc finger negative regulation of cytoplasmic translation Biological process 25737280 RSPO2 340419 R-spondin 2 positive regulation of canonical Wnt signaling pathway Biological process - AARS 16 alanyl-tRNA synthetase negative regulation of neuron apoptotic process Biological process - ALG6 29929 ALG6, alpha-1,3-glucosyltransferase endoplasmic reticulum membrane Cellular component - NUFIP1 26747 nuclear fragile X mental retardation protein interacting protein 1 pre-snoRNP complex Cellular component 17636026 GAS1 2619 growth arrest-specific 1 programmed cell death Biological process - SLC9A1 6548 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 protein oligomerization Biological process - CGN 57530 cingulin biological_process Biological process - NCOR1 9611 nuclear receptor corepressor 1 cytoplasm Cellular component - AIF1 199 allograft inflammatory factor 1 positive regulation of monocyte chemotaxis Biological process 15117732 POLR2M 81488 polymerase (RNA) II (DNA directed) polypeptide M neuronal cell body Cellular component - TRAK1 22906 trafficking protein, kinesin binding 1 mitochondrion Cellular component 15644324 ISL1 3670 ISL LIM homeobox 1 trigeminal nerve development Biological process - MGST3 4259 microsomal glutathione S-transferase 3 intracellular membrane-bounded organelle Cellular component 9278457 NF1 4763 neurofibromin 1 intrinsic component of the cytoplasmic side of the plasma membrane Cellular component - GJA1 2697 gap junction protein, alpha 1, 43kDa skeletal muscle tissue regeneration Biological process - SESN1 27244 sestrin 1 cell cycle arrest Biological process 9926927 IFNG 3458 interferon, gamma positive regulation of fructose 1,6-bisphosphate metabolic process Biological process 9282826 FUT8 2530 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) integrin-mediated signaling pathway Biological process - DNAJA3 9093 DnaJ (Hsp40) homolog, subfamily A, member 3 negative regulation of I-kappaB kinase/NF-kappaB signaling Biological process 11927590 NUP98 4928 nucleoporin 98kDa nucleocytoplasmic transport Biological process 9348540 RBM5 10181 RNA binding motif protein 5 nucleoplasm Cellular component - SPDL1 54908 spindle apparatus coiled-coil protein 1 protein localization to kinetochore Biological process 19468067 DMRT3 58524 doublesex and mab-3 related transcription factor 3 protein heterodimerization activity Molecular function - PGAP2 27315 post-GPI attachment to proteins 2 endoplasmic reticulum membrane Cellular component - PURG 29942 purine-rich element binding protein G poly(A) RNA binding Molecular function 22681889 CPB1 1360 carboxypeptidase B1 (tissue) metallocarboxypeptidase activity Molecular function - ITGAL 3683 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) plasma membrane Cellular component - BET1L 51272 Bet1 golgi vesicular membrane trafficking protein-like Golgi apparatus Cellular component 15215310 PARK2 5071 parkin RBR E3 ubiquitin protein ligase identical protein binding Molecular function 21694720 SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 condensed chromosome Cellular component 12972596 PCDHB15 56121 protocadherin beta 15 calcium ion binding Molecular function - STX12 23673 syntaxin 12 Golgi membrane Cellular component - TKFC 26007 triokinase/FMN cyclase regulation of innate immune response Biological process 16289032 DNASE2 1777 deoxyribonuclease II, lysosomal deoxyribonuclease II activity Molecular function - KDM1B 221656 lysine (K)-specific demethylase 1B transcription, DNA-templated Biological process - PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta T cell activation Biological process 20940048 XCL1 6375 chemokine (C motif) ligand 1 negative regulation of transcription, DNA-templated Biological process 10887101 SYT4 6860 synaptotagmin IV neuron projection Cellular component - LHX5 64211 LIM homeobox 5 sequence-specific DNA binding Molecular function - BTBD2 55643 BTB (POZ) domain containing 2 cytoplasmic mRNA processing body Cellular component 12878161 MAP2K4 6416 mitogen-activated protein kinase kinase 4 mitogen-activated protein kinase kinase kinase binding Molecular function - CCL16 6360 chemokine (C-C motif) ligand 16 immune response Biological process - PLK1 5347 polo-like kinase 1 protein serine/threonine kinase activity Molecular function 19473992 C2CD4D 100191040 C2 calcium-dependent domain containing 4D syntaxin binding Molecular function - ATP1A2 477 ATPase, Na+/K+ transporting, alpha 2 polypeptide metabolic process Biological process - VCAM1 7412 vascular cell adhesion molecule 1 chronic inflammatory response Biological process - TTR 7276 transthyretin retinoid metabolic process Biological process - CHUK 1147 conserved helix-loop-helix ubiquitous kinase toll-like receptor 9 signaling pathway Biological process - THBS1 7057 thrombospondin 1 cellular response to tumor necrosis factor Biological process - CDK5RAP3 80279 CDK5 regulatory subunit associated protein 3 positive regulation of transcription from RNA polymerase II promoter Biological process - PKP1 5317 plakophilin 1 lamin binding Molecular function 10852826 GSPT2 23708 G1 to S phase transition 2 cell cycle Biological process - HIF3A 64344 hypoxia inducible factor 3, alpha subunit positive regulation of transcription from RNA polymerase II promoter Biological process - UBQLN2 29978 ubiquilin 2 regulation of macroautophagy Biological process 20529957 HIST1H4A 8359 histone cluster 1, H4a histone binding Molecular function 20498094 SST 6750 somatostatin response to heat Biological process - GTF3C4 9329 general transcription factor IIIC, polypeptide 4, 90kDa histone acetyltransferase activity Molecular function - LYRM1 57149 LYR motif containing 1 mitochondrion Cellular component - CHST9 83539 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9 sulfur compound metabolic process Biological process 11445554 ABTB1 80325 ankyrin repeat and BTB (POZ) domain containing 1 nucleolus Cellular component - PDK4 5166 pyruvate dehydrogenase kinase, isozyme 4 reactive oxygen species metabolic process Biological process 21852536 PTS 5805 6-pyruvoyltetrahydropterin synthase protein binding Molecular function 25416956 CD5 921 CD5 molecule T cell costimulation Biological process - MAP9 79884 microtubule-associated protein 9 regulation of mitotic nuclear division Biological process - PLK2 10769 polo-like kinase 2 centrosome Cellular component 15242618 ALG9 79796 ALG9, alpha-1,2-mannosyltransferase endoplasmic reticulum membrane Cellular component - APOA1 335 apolipoprotein A-I chemorepellent activity Molecular function 23726972 ABCA7 10347 ATP-binding cassette, sub-family A (ABC1), member 7 apolipoprotein A-I receptor activity Molecular function 14570867 PLAUR 5329 plasminogen activator, urokinase receptor receptor activity Molecular function 1689240 HOXA1 3198 homeobox A1 anatomical structure morphogenesis Biological process 16155570 ITPR3 3710 inositol 1,4,5-trisphosphate receptor, type 3 brush border Cellular component 8288584 BMP2 650 bone morphogenetic protein 2 SMAD binding Molecular function 18184661 ESRRG 2104 estrogen-related receptor gamma RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - TSSK1B 83942 testis-specific serine kinase 1B intracellular signal transduction Biological process - POLA1 5422 polymerase (DNA directed), alpha 1, catalytic subunit DNA binding Molecular function 3359994 CREB3 10488 cAMP responsive element binding protein 3 integral component of endoplasmic reticulum membrane Cellular component 20546900 AGO3 192669 argonaute RISC catalytic component 3 mRNA cleavage involved in gene silencing by siRNA Biological process 15260970 NCF4 4689 neutrophil cytosolic factor 4, 40kDa phagolysosome Cellular component - PTEN 5728 phosphatase and tensin homolog central nervous system development Biological process - CEP131 22994 centrosomal protein 131kDa intercellular bridge Cellular component - SLC1A5 6510 solute carrier family 1 (neutral amino acid transporter), member 5 integral component of plasma membrane Cellular component 8702519 APAF1 317 apoptotic peptidase activating factor 1 cytosol Cellular component - CA14 23632 carbonic anhydrase XIV small molecule metabolic process Biological process - YWHAE 7531 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon membrane Cellular component 19946888 OR5AL1 79482 olfactory receptor, family 5, subfamily AL, member 1 (gene/pseudogene) G-protein coupled receptor activity Molecular function - FGFR2 2263 fibroblast growth factor receptor 2 positive regulation of epithelial cell proliferation involved in lung morphogenesis Biological process - RFTN1 23180 raftlin, lipid raft linker 1 B cell receptor signaling pathway Biological process 12805216 TAAR3 9288 trace amine associated receptor 3 (gene/pseudogene) integral component of membrane Cellular component - INSL3 3640 insulin-like 3 (Leydig cell) in utero embryonic development Biological process - ELN 2006 elastin cell proliferation Biological process 9607766 CGNL1 84952 cingulin-like 1 metabolic process Biological process - GATA3 2625 GATA binding protein 3 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function - ALKBH2 121642 alkB, alkylation repair homolog 2 (E. coli) cytosine C-5 DNA demethylase activity Molecular function 18775698 HBB 3043 hemoglobin, beta receptor-mediated endocytosis Biological process - TRAP1 10131 TNF receptor-associated protein 1 chaperone-mediated protein folding Biological process 24522549 CTDP1 9150 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 spindle pole Cellular component 22692537 TXNL1 9352 thioredoxin-like 1 glycerol ether metabolic process Biological process - IRAK2 3656 interleukin-1 receptor-associated kinase 2 protein heterodimerization activity Molecular function 10383454 CD74 972 CD74 molecule, major histocompatibility complex, class II invariant chain extracellular exosome Cellular component 20458337 PRDM7 11105 PR domain containing 7 chromosome Cellular component - GSC 145258 goosecoid homeobox transcription factor complex Cellular component - RPTOR 57521 regulatory associated protein of MTOR, complex 1 RNA polymerase III type 2 promoter DNA binding Molecular function 20233713 TIMD4 91937 T-cell immunoglobulin and mucin domain containing 4 integral component of membrane Cellular component - FAM3A 60343 family with sequence similarity 3, member A biological_process Biological process - CELF4 56853 CUGBP, Elav-like family member 4 germ cell development Biological process 10893231 CHD5 26038 chromodomain helicase DNA binding protein 5 transcription from RNA polymerase II promoter Biological process - CACNB2 783 calcium channel, voltage-dependent, beta 2 subunit neuromuscular junction development Biological process 8494331 SCAMP2 10066 secretory carrier membrane protein 2 nucleoplasm Cellular component - FAT4 79633 FAT atypical cadherin 4 plasma membrane Cellular component - DOPEY2 9980 dopey family member 2 Golgi to endosome transport Biological process 16301316 RSU1 6251 Ras suppressor protein 1 focal adhesion Cellular component 20926685 WNT1 7471 wingless-type MMTV integration site family, member 1 positive regulation of protein phosphorylation Biological process - MME 4311 membrane metallo-endopeptidase plasma membrane Cellular component - LTBP1 4052 latent transforming growth factor beta binding protein 1 transmembrane receptor protein serine/threonine kinase signaling pathway Biological process 8537398 RBFOX3 146713 RNA binding protein, fox-1 homolog (C. elegans) 3 DNA binding Molecular function - RRAGD 58528 Ras-related GTP binding D lysosome Cellular component 20381137 SEC22C 9117 SEC22 vesicle trafficking protein homolog C (S. cerevisiae) SNARE binding Molecular function - IRS2 8660 insulin receptor substrate 2 innate immune response Biological process - SHH 6469 sonic hedgehog formation of anatomical boundary Biological process - UBXN1 51035 UBX domain protein 1 dendrite Cellular component - SLC34A1 6569 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 brush border membrane Cellular component 8693007 RAB3A 5864 RAB3A, member RAS oncogene family protein binding Molecular function 10859313 DAB2IP 153090 DAB2 interacting protein parallel fiber Cellular component - EGR1 1958 early growth response 1 learning or memory Biological process - HTRA2 27429 HtrA serine peptidase 2 membrane Cellular component 24798695 TUBB 203068 tubulin, beta class I cell body Cellular component 19567321 KCNH8 131096 potassium channel, voltage gated eag related subfamily H, member 8 regulation of ion transmembrane transport Biological process - PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide platelet-derived growth factor receptor-beta signaling pathway Biological process 2554309 LYNX1 66004 Ly6/neurotoxin 1 anchored component of membrane Cellular component - GABARAPL2 11345 GABA(A) receptor-associated protein-like 2 negative regulation of proteasomal protein catabolic process Biological process 21669198 CXCR3 2833 chemokine (C-X-C motif) receptor 3 cell adhesion Biological process 10942362 GPER1 2852 G protein-coupled estrogen receptor 1 apoptotic chromosome condensation Biological process - PURA 5813 purine-rich element binding protein A neuronal cell body Cellular component - SUV39H1 6839 suppressor of variegation 3-9 homolog 1 (Drosophila) cellular response to DNA damage stimulus Biological process 23509280 FHIT 2272 fragile histidine triad nucleotide binding Molecular function - YES1 7525 YES proto-oncogene 1, Src family tyrosine kinase epidermal growth factor receptor binding Molecular function - ATP5B 506 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide ATP hydrolysis coupled proton transport Biological process - CLDN19 149461 claudin 19 neuronal action potential propagation Biological process - MOB1B 92597 MOB kinase activator 1B kinase binding Molecular function 15197186 OR2A12 346525 olfactory receptor, family 2, subfamily A, member 12 sensory perception of smell Biological process - NUP88 4927 nucleoporin 88kDa cellular protein metabolic process Biological process - CASP8 841 caspase 8, apoptosis-related cysteine peptidase toll-like receptor 3 signaling pathway Biological process - EP400 57634 E1A binding protein p400 nucleoplasm Cellular component - BMP3 651 bone morphogenetic protein 3 cartilage development Biological process - ALDH1A3 220 aldehyde dehydrogenase 1 family, member A3 cytoplasm Cellular component 11585737 NAP1L4 4676 nucleosome assembly protein 1-like 4 nucleus Cellular component - BRINP1 1620 bone morphogenetic protein/retinoic acid inducible neural-specific 1 cytoplasm Cellular component 11420708 LSM10 84967 LSM10, U7 small nuclear RNA associated histone pre-mRNA DCP binding Molecular function - ZNRF1 84937 zinc and ring finger 1, E3 ubiquitin protein ligase protein binding Molecular function 19549727 POLR1A 25885 polymerase (RNA) I polypeptide A, 194kDa DNA binding Molecular function - RPF2 84154 ribosome production factor 2 homolog (S. cerevisiae) nucleus Cellular component - PITPNB 23760 phosphatidylinositol transfer protein, beta Golgi membrane Cellular component - MITF 4286 microphthalmia-associated transcription factor positive regulation of transcription, DNA-templated Biological process 10578055 RFX3 5991 regulatory factor X, 3 (influences HLA class II expression) nuclear chromatin Cellular component 20413507 OR10AC1 392133 olfactory receptor, family 10, subfamily AC, member 1 (gene/pseudogene) olfactory receptor activity Molecular function - THY1 7070 Thy-1 cell surface antigen focal adhesion assembly Biological process - GBF1 8729 golgi brefeldin A resistant guanine nucleotide exchange factor 1 phosphatidylinositol-3,5-bisphosphate binding Molecular function 22573891 ESYT2 57488 extended synaptotagmin-like protein 2 endoplasmic reticulum Cellular component - TXK 7294 TXK tyrosine kinase transcription, DNA-templated Biological process - LST1 7940 leukocyte specific transcript 1 Golgi apparatus Cellular component 11478849 ASIC1 41 acid sensing (proton gated) ion channel 1 integral component of plasma membrane Cellular component - KCNN3 3782 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 neuronal cell body Cellular component - H1F0 3005 H1 histone family, member 0 chromatin DNA binding Molecular function 15911621 ITGA6 3655 integrin, alpha 6 basal plasma membrane Cellular component - NSL1 25936 NSL1, MIS12 kinetochore complex component mitotic cell cycle Biological process - IFITM3 10410 interferon induced transmembrane protein 3 plasma membrane Cellular component - DPEP3 64180 dipeptidase 3 dipeptidyl-peptidase activity Molecular function - RPSA 3921 ribosomal protein SA viral transcription Biological process - HIST1H4B 8366 histone cluster 1, H4b nucleus Cellular component 14585971 GIMAP1 170575 GTPase, IMAP family member 1 Golgi membrane Cellular component - CDH15 1013 cadherin 15, type 1, M-cadherin (myotubule) extracellular exosome Cellular component 23533145 EGR1 1958 early growth response 1 cellular response to growth factor stimulus Biological process - HP1BP3 50809 heterochromatin protein 1, binding protein 3 cellular response to hypoxia Biological process 25100860 CALR 811 calreticulin receptor-mediated endocytosis Biological process - PROC 5624 protein C (inactivator of coagulation factors Va and VIIIa) endoplasmic reticulum lumen Cellular component - HOXB5 3215 homeobox B5 protein binding Molecular function 25416956 FHOD3 80206 formin homology 2 domain containing 3 cardiac myofibril assembly Biological process - CNOT7 29883 CCR4-NOT transcription complex, subunit 7 protein binding Molecular function 11136725 SYNGAP1 8831 synaptic Ras GTPase activating protein 1 Ras protein signal transduction Biological process - TCAP 8557 titin-cap protein binding, bridging Molecular function 15582318 POU3F1 5453 POU class 3 homeobox 1 transcription, DNA-templated Biological process - TIMP4 7079 TIMP metallopeptidase inhibitor 4 extracellular space Cellular component - CYP1B1 1545 cytochrome P450, family 1, subfamily B, polypeptide 1 mitochondrion Cellular component - MBD4 8930 methyl-CpG binding domain protein 4 depyrimidination Biological process - GAS6 2621 growth arrest-specific 6 cell cycle arrest Biological process 16564713 SNX4 8723 sorting nexin 4 early endosome membrane Cellular component 17994011 CDC42 998 cell division cycle 42 GTPase activity Molecular function 11035016 EIF2S2 8894 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa in utero embryonic development Biological process - SLC23A2 9962 solute carrier family 23 (ascorbic acid transporter), member 2 sodium ion transport Biological process - CLN3 1201 ceroid-lipofuscinosis, neuronal 3 Golgi stack Cellular component 15240864 ZNF79 7633 zinc finger protein 79 protein binding Molecular function 25416956 ATP6V1A 523 ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A ATP binding Molecular function - MEF2A 4205 myocyte enhancer factor 2A cytoplasm Cellular component - GSS 2937 glutathione synthetase glycine binding Molecular function - PIGL 9487 phosphatidylinositol glycan anchor biosynthesis, class L C-terminal protein lipidation Biological process - PTCH1 5727 patched 1 keratinocyte proliferation Biological process - ADPRM 56985 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent ADP-ribose diphosphatase activity Molecular function - EP300 2033 E1A binding protein p300 pre-mRNA intronic binding Molecular function - CALR 811 calreticulin positive regulation of DNA replication Biological process 14726956 AGTR2 186 angiotensin II receptor, type 2 cellular response to dexamethasone stimulus Biological process - GRM2 2912 glutamate receptor, metabotropic 2 synaptic transmission Biological process 7620613 NCMAP 400746 noncompact myelin associated protein peripheral nervous system myelin formation Biological process - LSM8 51691 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) poly(A) RNA binding Molecular function 22658674 RPP30 10556 ribonuclease P/MRP 30kDa subunit protein binding Molecular function 25416956 WAC 51322 WW domain containing adaptor with coiled-coil positive regulation of macroautophagy Biological process 22354037 RAG2 5897 recombination activating gene 2 phosphatidylinositol-4,5-bisphosphate binding Molecular function - PLCH2 9651 phospholipase C, eta 2 cellular_component Cellular component - IFT20 90410 intraflagellar transport 20 regulation of autophagosome assembly Biological process - ANKRD36BP1 84832 ankyrin repeat domain 36B pseudogene 1 protein binding Molecular function 16189514 CIRBP 1153 cold inducible RNA binding protein response to UV Biological process 11574538 DNASE2B 58511 deoxyribonuclease II beta lysosome Cellular component - LIMCH1 22998 LIM and calponin homology domains 1 zinc ion binding Molecular function - SRPX 8406 sushi-repeat containing protein, X-linked cell surface Cellular component - SLC25A12 8604 solute carrier family 25 (aspartate/glutamate carrier), member 12 gluconeogenesis Biological process - ID2 3398 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein negative regulation of oligodendrocyte differentiation Biological process - HFE 3077 hemochromatosis protein binding Molecular function 10638746 PARM1 25849 prostate androgen-regulated mucin-like protein 1 positive regulation of telomerase activity Biological process - FAS 355 Fas cell surface death receptor extrinsic apoptotic signaling pathway via death domain receptors Biological process - KDELR1 10945 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 intracellular protein transport Biological process 2172835 IL2 3558 interleukin 2 regulation of T cell homeostatic proliferation Biological process - PAX1 5075 paired box 1 somitogenesis Biological process - ZNF30 90075 zinc finger protein 30 sequence-specific DNA binding transcription factor activity Molecular function - NCBP1 4686 nuclear cap binding protein subunit 1, 80kDa transcription from RNA polymerase II promoter Biological process - MBD4 8930 methyl-CpG binding domain protein 4 response to radiation Biological process - TAF1L 138474 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like regulation of transcription from RNA polymerase II promoter Biological process 12217962 KIF14 9928 kinesin family member 14 PDZ domain binding Molecular function 23209302 MKKS 8195 McKusick-Kaufman syndrome cerebral cortex development Biological process - CATSPER2 117155 cation channel, sperm associated 2 multicellular organismal development Biological process - SIGLEC11 114132 sialic acid binding Ig-like lectin 11 cell adhesion Biological process - SULT4A1 25830 sulfotransferase family 4A, member 1 xenobiotic metabolic process Biological process - GLP2R 9340 glucagon-like peptide 2 receptor G-protein coupled receptor activity Molecular function 9990065 DYRK3 8444 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 nucleus Cellular component 10779429 NFAT5 10725 nuclear factor of activated T-cells 5, tonicity-responsive cytoplasm Cellular component - MAP2K2 5605 mitogen-activated protein kinase kinase 2 small GTPase mediated signal transduction Biological process - MMP20 9313 matrix metallopeptidase 20 extracellular region Cellular component - GPR89A 653519 G protein-coupled receptor 89A voltage-gated anion channel activity Molecular function 18794847 CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa lung induction Biological process - H6PD 9563 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) pentose-phosphate shunt Biological process - C1QTNF9B-AS1 542767 C1QTNF9B antisense RNA 1 cytoplasm Cellular component - MUC12 10071 mucin 12, cell surface associated integral component of plasma membrane Cellular component 10463611 ANPEP 290 alanyl (membrane) aminopeptidase metallopeptidase activity Molecular function - SLC25A22 79751 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 L-glutamate transmembrane transporter activity Molecular function 11897791 SEC63 11231 SEC63 homolog (S. cerevisiae) IRE1-mediated unfolded protein response Biological process - STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) signal transducer activity Molecular function - ITGAL 3683 integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) ICAM-3 receptor activity Molecular function 19029120 PPP1R12C 54776 protein phosphatase 1, regulatory subunit 12C protein binding Molecular function 21988832 PPARGC1A 10891 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha chromatin DNA binding Molecular function - LPAR1 1902 lysophosphatidic acid receptor 1 lysophosphatidic acid receptor activity Molecular function - UXT 8409 ubiquitously-expressed, prefoldin-like chaperone chromatin binding Molecular function 21730289 FOS 2353 FBJ murine osteosarcoma viral oncogene homolog nucleoplasm Cellular component - INSL4 3641 insulin-like 4 (placenta) signal transduction Biological process 8702754 TAX1BP3 30851 Tax1 (human T-cell leukemia virus type I) binding protein 3 extracellular exosome Cellular component 19056867 SERPINF2 5345 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 positive regulation of smooth muscle cell proliferation Biological process - PAK6 56924 p21 protein (Cdc42/Rac)-activated kinase 6 Rac GTPase binding Molecular function - COL11A2 1302 collagen, type XI, alpha 2 endoplasmic reticulum lumen Cellular component - SPR 6697 sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) dopamine metabolic process Biological process - NLGN3 54413 neuroligin 3 positive regulation of synaptic transmission, glutamatergic Biological process - PTRF 284119 polymerase I and transcript release factor protein complex Cellular component 24013648 IRX4 50805 iroquois homeobox 4 heart development Biological process - TAPBP 6892 TAP binding protein (tapasin) amide transport Biological process 9238042 AQP5 362 aquaporin 5 basal plasma membrane Cellular component - CPSF3L 54973 cleavage and polyadenylation specific factor 3-like cytoplasm Cellular component - IGF2R 3482 insulin-like growth factor 2 receptor focal adhesion Cellular component 21423176 MMP1 4312 matrix metallopeptidase 1 viral process Biological process - CINP 51550 cyclin-dependent kinase 2 interacting protein nucleus Cellular component - UBE2B 7320 ubiquitin-conjugating enzyme E2B sperm axoneme assembly Biological process - FCGR3B 2215 Fc fragment of IgG, low affinity IIIb, receptor (CD16b) immune response Biological process 2139735 ACLY 47 ATP citrate lyase small molecule metabolic process Biological process - MYO1B 4430 myosin IB extracellular exosome Cellular component 19056867 EFNB1 1947 ephrin-B1 positive regulation of T cell proliferation Biological process - LACTB 114294 lactamase, beta hydrolase activity Molecular function - LSM3 27258 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) mRNA splicing, via spliceosome Biological process 11991638 ZNF469 84627 zinc finger protein 469 DNA binding Molecular function - ZNF284 342909 zinc finger protein 284 nucleus Cellular component - NUP35 129401 nucleoporin 35kDa regulation of glucose transport Biological process - NODAL 4838 nodal growth differentiation factor left lung morphogenesis Biological process - ARL8A 127829 ADP-ribosylation factor-like 8A GTPase activity Molecular function 15331635 B4GALT6 9331 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 galactosyltransferase activity Molecular function 9597550 TOM1L1 10040 target of myb1 (chicken)-like 1 endosome membrane Cellular component - TNFRSF1B 7133 tumor necrosis factor receptor superfamily, member 1B tumor necrosis factor-mediated signaling pathway Biological process 8702885 PPIH 10465 peptidylprolyl isomerase H (cyclophilin H) protein folding Biological process - STAB2 55576 stabilin 2 regulation of gene expression Biological process 21810271 ABCB11 8647 ATP-binding cassette, sub-family B (MDR/TAP), member 11 ATP binding Molecular function - CPEB3 22849 cytoplasmic polyadenylation element binding protein 3 apical dendrite Cellular component - RARRES2 5919 retinoic acid receptor responder (tazarotene induced) 2 positive regulation of chemotaxis Biological process - SFRP2 6423 secreted frizzled-related protein 2 positive regulation of cell growth Biological process 10980594 PRKRA 8575 protein kinase, interferon-inducible double stranded RNA dependent activator cytoplasm Cellular component - FOXC1 2296 forkhead box C1 transcription from RNA polymerase II promoter Biological process - NANOS2 339345 nanos homolog 2 (Drosophila) perinuclear region of cytoplasm Cellular component 19168545 PDXK 8566 pyridoxal (pyridoxine, vitamin B6) kinase zinc ion binding Molecular function 10987144 ERCC3 2071 excision repair cross-complementation group 3 ATPase activity Molecular function 17466626 OR10H4 126541 olfactory receptor, family 10, subfamily H, member 4 integral component of membrane Cellular component - AAMDC 28971 adipogenesis associated, Mth938 domain containing positive regulation of fat cell differentiation Biological process - SNRPD3 6634 small nuclear ribonucleoprotein D3 polypeptide 18kDa poly(A) RNA binding Molecular function 22681889 LRRK2 120892 leucine-rich repeat kinase 2 actin binding Molecular function 21307259 HEXIM2 124790 hexamethylene bis-acetamide inducible 2 negative regulation of transcription from RNA polymerase II promoter Biological process 15713662 ARRB1 408 arrestin, beta 1 positive regulation of transcription from RNA polymerase II promoter Biological process 16325578 MEN1 4221 multiple endocrine neoplasia I cell cycle arrest Biological process - SUN2 25777 Sad1 and UNC84 domain containing 2 positive regulation of cell migration Biological process - FOXA2 3170 forkhead box A2 cell differentiation in hindbrain Biological process - GAS6 2621 growth arrest-specific 6 signal transduction Biological process 16564713 PMEL 6490 premelanosome protein melanin biosynthetic process Biological process - ARHGEF1 9138 Rho guanine nucleotide exchange factor (GEF) 1 negative regulation of axonogenesis Biological process - PRKAR2A 5576 protein kinase, cAMP-dependent, regulatory, type II, alpha regulation of insulin secretion Biological process - GPER1 2852 G protein-coupled estrogen receptor 1 positive regulation of gene expression Biological process - PRDX3 10935 peroxiredoxin 3 cellular response to oxidative stress Biological process 21850687 CEL 1056 carboxyl ester lipase lipid digestion Biological process - ZSCAN30 100101467 zinc finger and SCAN domain containing 30 nucleus Cellular component - ASNS 440 asparagine synthetase (glutamine-hydrolyzing) response to toxic substance Biological process - SH2D2A 9047 SH2 domain containing 2A vascular endothelial growth factor receptor signaling pathway Biological process - PHF5A 84844 PHD finger protein 5A RNA splicing Biological process - SDR16C5 195814 short chain dehydrogenase/reductase family 16C, member 5 retinol metabolic process Biological process - AHR 196 aryl hydrocarbon receptor negative regulation of transcription from RNA polymerase II promoter Biological process - OPTN 10133 optineurin identical protein binding Molecular function 23414517 S100A12 6283 S100 calcium binding protein A12 cytosol Cellular component 18443896 CATSPERD 257062 catsper channel auxiliary subunit delta sperm principal piece Cellular component - UQCRH 7388 ubiquinol-cytochrome c reductase hinge protein small molecule metabolic process Biological process - SYT10 341359 synaptotagmin X calcium-dependent phospholipid binding Molecular function - SMAD5 4090 SMAD family member 5 bone development Biological process - BLOC1S5 63915 biogenesis of lysosomal organelles complex-1, subunit 5, muted melanosome organization Biological process 22203680 SYNJ1 8867 synaptojanin 1 phosphatidylinositol phosphate 5-phosphatase activity Molecular function - SYCP1 6847 synaptonemal complex protein 1 male germ cell nucleus Cellular component - FASN 2194 fatty acid synthase myristoyl-[acyl-carrier-protein] hydrolase activity Molecular function - ADCY6 112 adenylate cyclase 6 metal ion binding Molecular function - IREB2 3658 iron-responsive element binding protein 2 cytoplasm Cellular component 7983023 PIP5K1C 23396 phosphatidylinositol-4-phosphate 5-kinase, type I, gamma synaptic vesicle exocytosis Biological process 19889969 PPM1B 5495 protein phosphatase, Mg2+/Mn2+ dependent, 1B negative regulation of defense response to virus Biological process 22750291 BMP4 652 bone morphogenetic protein 4 odontogenesis Biological process 11023873 MAPK3 5595 mitogen-activated protein kinase 3 insulin receptor signaling pathway Biological process - RUNX1T1 862 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) metal ion binding Molecular function - SLC9A3 6550 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 plasma membrane Cellular component - OR7G2 390882 olfactory receptor, family 7, subfamily G, member 2 olfactory receptor activity Molecular function - MAN2C1 4123 mannosidase, alpha, class 2C, member 1 carbohydrate binding Molecular function - COLEC12 81035 collectin sub-family member 12 receptor-mediated endocytosis Biological process - NRXN1 9378 neurexin 1 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Biological process - CHMP4B 128866 charged multivesicular body protein 4B viral life cycle Biological process - PPP2R1A 5518 protein phosphatase 2, regulatory subunit A, alpha nucleus Cellular component 11007961 CRYGA 1418 crystallin, gamma A lens development in camera-type eye Biological process - SPATA31A6 389730 SPATA31 subfamily A, member 6 cell differentiation Biological process - RAB3C 115827 RAB3C, member RAS oncogene family myosin V binding Molecular function 24006491 MC1R 4157 melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) positive regulation of protein kinase C signaling Biological process 18292087 HES6 55502 hes family bHLH transcription factor 6 sequence-specific DNA binding transcription factor activity Molecular function - SPATA25 128497 spermatogenesis associated 25 cell differentiation Biological process - LHCGR 3973 luteinizing hormone/choriogonadotropin receptor adenylate cyclase-activating G-protein coupled receptor signaling pathway Biological process - BBS12 166379 Bardet-Biedl syndrome 12 intraciliary transport Biological process - HLA-A 3105 major histocompatibility complex, class I, A integral component of plasma membrane Cellular component 6609814 EGLN1 54583 egl-9 family hypoxia-inducible factor 1 negative regulation of cyclic-nucleotide phosphodiesterase activity Biological process - GLRX2 51022 glutaredoxin 2 cell redox homeostasis Biological process 11397793 IL23R 149233 interleukin 23 receptor interleukin-23 receptor complex Cellular component 12023369 HLA-DRB3 3125 major histocompatibility complex, class II, DR beta 3 clathrin-coated endocytic vesicle membrane Cellular component - KHDC1 80759 KH homology domain containing 1 integral component of membrane Cellular component - HMBS 3145 hydroxymethylbilane synthase heme biosynthetic process Biological process - MTBP 27085 MDM2 binding protein protein localization to kinetochore Biological process 21274008 GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A plasma membrane Cellular component - USF1 7391 upstream transcription factor 1 nucleoplasm Cellular component - TNFRSF19 55504 tumor necrosis factor receptor superfamily, member 19 apoptotic process Biological process 10809768 ARHGAP21 57584 Rho GTPase activating protein 21 cytoskeleton Cellular component - SIGMAR1 10280 sigma non-opioid intracellular receptor 1 growth cone Cellular component - COX15 1355 cytochrome c oxidase assembly homolog 15 (yeast) mitochondrial inner membrane Cellular component - FER 2241 fer (fps/fes related) tyrosine kinase platelet-derived growth factor receptor signaling pathway Biological process 11994747 HNRNPD 3184 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) protein binding Molecular function 12107167 LEO1 123169 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) negative regulation of myeloid cell differentiation Biological process 20541477 MPDU1 9526 mannose-P-dolichol utilization defect 1 extracellular exosome Cellular component 23376485 ZBTB7A 51341 zinc finger and BTB domain containing 7A negative regulation of transcription from RNA polymerase II promoter Biological process - TRAPPC6A 79090 trafficking protein particle complex 6A Golgi apparatus Cellular component - AMBRA1 55626 autophagy/beclin-1 regulator 1 autophagosome Cellular component - PID1 55022 phosphotyrosine interaction domain containing 1 positive regulation of reactive oxygen species metabolic process Biological process 20165904 ABCA11P 79963 ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene ATP binding Molecular function - GPD1L 23171 glycerol-3-phosphate dehydrogenase 1-like positive regulation of sodium ion transport Biological process 17967977 GTF2H4 2968 general transcription factor IIH, polypeptide 4, 52kDa holo TFIIH complex Cellular component 9852112 NUDT3 11165 nudix (nucleoside diphosphate linked moiety X)-type motif 3 diphosphoinositol-polyphosphate diphosphatase activity Molecular function 10585413 DPYSL3 1809 dihydropyrimidinase-like 3 actin crosslink formation Biological process - HSPA1A 3303 heat shock 70kDa protein 1A enzyme binding Molecular function 23921388 EMP3 2014 epithelial membrane protein 3 cell death Biological process 12107182 KIF25 3834 kinesin family member 25 microtubule motor activity Molecular function - LAMP5 24141 lysosomal-associated membrane protein family, member 5 endoplasmic reticulum-Golgi intermediate compartment membrane Cellular component 21642595 SLC35D2 11046 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 pyrimidine nucleotide-sugar transmembrane transporter activity Molecular function - RAPGEF3 10411 Rap guanine nucleotide exchange factor (GEF) 3 membrane Cellular component 10777494 EPHB1 2047 EPH receptor B1 protein autophosphorylation Biological process 18034775 CNR1 1268 cannabinoid receptor 1 (brain) response to nutrient Biological process - TSPEAR 54084 thrombospondin-type laminin G domain and EAR repeats cell surface Cellular component - OSGEP 55644 O-sialoglycoprotein endopeptidase transferase activity, transferring acyl groups Molecular function - KIF26B 55083 kinesin family member 26B microtubule-based movement Biological process - DRAM2 128338 DNA-damage regulated autophagy modulator 2 integral component of membrane Cellular component - PPP1R21 129285 protein phosphatase 1, regulatory subunit 21 membrane Cellular component 19946888 ARL17B 100506084 ADP-ribosylation factor-like 17B vesicle-mediated transport Biological process - TUBB2A 7280 tubulin, beta 2A class IIa extracellular exosome Cellular component 19056867 INHBA 3624 inhibin, beta A hair follicle development Biological process 10932194 TRAM2 9697 translocation associated membrane protein 2 protein transport Biological process - UNC13C 440279 unc-13 homolog C (C. elegans) exocytosis Biological process - YIPF5 81555 Yip1 domain family, member 5 ER to Golgi transport vesicle Cellular component - AGMO 392636 alkylglycerol monooxygenase oxidation-reduction process Biological process - CSF2RB 1439 colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) protein binding Molecular function 1495999 ZNF567 163081 zinc finger protein 567 metal ion binding Molecular function - HMGN5 79366 high mobility group nucleosome binding domain 5 regulation of transcription from RNA polymerase II promoter Biological process - VIL1 7429 villin 1 positive regulation of lamellipodium morphogenesis Biological process 18054784 GCK 2645 glucokinase (hexokinase 4) positive regulation of glycogen biosynthetic process Biological process 8878425 APC 324 adenomatous polyposis coli cytoplasmic microtubule organization Biological process - CRY1 1407 cryptochrome circadian clock 1 transcription factor binding transcription factor activity Molecular function 15147242 MYLPF 29895 myosin light chain, phosphorylatable, fast skeletal muscle structural constituent of muscle Molecular function - UQCR11 10975 ubiquinol-cytochrome c reductase, complex III subunit XI mitochondrial inner membrane Cellular component - CGNL1 84952 cingulin-like 1 motor activity Molecular function - PDE5A 8654 phosphodiesterase 5A, cGMP-specific metal ion binding Molecular function - MRPS23 51649 mitochondrial ribosomal protein S23 ribosome Cellular component - TRAPPC2 6399 trafficking protein particle complex 2 regulation of transcription, DNA-templated Biological process 11134351 TMX3 54495 thioredoxin-related transmembrane protein 3 response to endoplasmic reticulum stress Biological process - EXOSC4 54512 exosome component 4 cytoplasmic exosome (RNase complex) Cellular component - MAPK4 5596 mitogen-activated protein kinase 4 protein binding Molecular function 22939624 NCKAP1L 3071 NCK-associated protein 1-like positive regulation of CD8-positive, alpha-beta T cell differentiation Biological process - A4GNT 51146 alpha-1,4-N-acetylglucosaminyltransferase Golgi membrane Cellular component - CD86 942 CD86 molecule response to interferon-gamma Biological process - ZNF511 118472 zinc finger protein 511 regulation of transcription, DNA-templated Biological process - SYT17 51760 synaptotagmin XVII calcium-dependent phospholipid binding Molecular function - TET2 54790 tet methylcytosine dioxygenase 2 positive regulation of transcription from RNA polymerase II promoter Biological process 23222540 THEMIS2 9473 thymocyte selection associated family member 2 cell adhesion Biological process 9563507 MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase response to morphine Biological process - F11 2160 coagulation factor XI positive regulation of fibrinolysis Biological process 89876 PICALM 8301 phosphatidylinositol binding clathrin assembly protein iron ion homeostasis Biological process 22952941 MYOD1 4654 myogenic differentiation 1 nuclear chromatin Cellular component - CAT 847 catalase plasma membrane Cellular component - AP1G1 164 adaptor-related protein complex 1, gamma 1 subunit trans-Golgi network membrane Cellular component - APIP 51074 APAF1 interacting protein L-methionine biosynthetic process from methylthioadenosine Biological process - MTA2 9219 metastasis associated 1 family, member 2 chromatin organization Biological process - HOXD1 3231 homeobox D1 sequence-specific DNA binding Molecular function - MPO 4353 myeloperoxidase chromatin binding Molecular function 2829220 PIN4 5303 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 preribosome Cellular component 19369196 TGFB1 7040 transforming growth factor, beta 1 negative regulation of transcription, DNA-templated Biological process 15702480 NDUFAF2 91942 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 NADH dehydrogenase (ubiquinone) activity Molecular function - FAM49B 51571 family with sequence similarity 49, member B protein binding Molecular function 25416956 KIAA1804 84451 mixed lineage kinase 4 MAP kinase kinase kinase activity Molecular function - CNGA1 1259 cyclic nucleotide gated channel alpha 1 regulation of membrane potential Biological process - EVL 51466 Enah/Vasp-like actin binding Molecular function - TGM2 7052 transglutaminase 2 positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process - NPHP4 261734 nephronophthisis 4 sperm motility Biological process - T 6862 T, brachyury homolog (mouse) embryonic skeletal system development Biological process - FCN2 2220 ficolin (collagen/fibrinogen domain containing lectin) 2 collagen trimer Cellular component - HSP90B1 7184 heat shock protein 90kDa beta (Grp94), member 1 ATP binding Molecular function - SPATA7 55812 spermatogenesis associated 7 photoreceptor connecting cilium Cellular component - FFAR2 2867 free fatty acid receptor 2 positive regulation of interleukin-8 secretion Biological process 21037097 INPP5J 27124 inositol polyphosphate-5-phosphatase J plasma membrane Cellular component - PAPOLG 64895 poly(A) polymerase gamma nucleus Cellular component - TCIRG1 10312 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 phagosome maturation Biological process - GALR1 2587 galanin receptor 1 adenylate cyclase-activating G-protein coupled receptor signaling pathway Biological process - TKFC 26007 triokinase/FMN cyclase cytosol Cellular component - EIF5 1983 eukaryotic translation initiation factor 5 translation Biological process - MAP2K1 5604 mitogen-activated protein kinase kinase 1 extracellular exosome Cellular component 23376485 SUZ12 23512 SUZ12 polycomb repressive complex 2 subunit gene expression Biological process - TRABD2B 388630 TraB domain containing 2B integral component of organelle membrane Cellular component 22726442 TCN2 6948 transcobalamin II extracellular exosome Cellular component 23376485 AKAP13 11214 A kinase (PRKA) anchor protein 13 protein phosphorylation Biological process 1618839 ARIH1 25820 ariadne RBR E3 ubiquitin protein ligase 1 protein binding Molecular function 10521492 UBE2J2 118424 ubiquitin-conjugating enzyme E2, J2 response to unfolded protein Biological process - PSMB9 5698 proteasome (prosome, macropain) subunit, beta type, 9 protein binding Molecular function 14733938 RELA 5970 v-rel avian reticuloendotheliosis viral oncogene homolog A response to insulin Biological process - SLC17A1 6568 solute carrier family 17 (organic anion transporter), member 1 sodium:phosphate symporter activity Molecular function - TUFM 7284 Tu translation elongation factor, mitochondrial GTP binding Molecular function - HMGN5 79366 high mobility group nucleosome binding domain 5 positive regulation of transcription, DNA-templated Biological process 11161810 CREBRF 153222 CREB3 regulatory factor sequence-specific DNA binding Molecular function - ADAM10 102 ADAM metallopeptidase domain 10 cell-cell signaling Biological process 12714508 ANPEP 290 alanyl (membrane) aminopeptidase extracellular space Cellular component 16502470 SLC18A2 6571 solute carrier family 18 (vesicular monoamine transporter), member 2 insulin secretion Biological process - METRN 79006 meteorin, glial cell differentiation regulator glial cell differentiation Biological process - FAM134B 54463 family with sequence similarity 134, member B sensory perception of pain Biological process 19838196 SIX3 6496 SIX homeobox 3 lens development in camera-type eye Biological process - ADORA2B 136 adenosine A2b receptor adenylate cyclase-activating G-protein coupled receptor signaling pathway Biological process - CLCN5 1184 chloride channel, voltage-sensitive 5 lysosomal membrane Cellular component 17897319 CRHR1 1394 corticotropin releasing hormone receptor 1 corticotropin-releasing hormone binding Molecular function - RPS27A 6233 ribosomal protein S27a JNK cascade Biological process - KIR3DS1 3813 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 innate immune response Biological process - LMTK2 22853 lemur tyrosine kinase 2 recycling endosome Cellular component 18029400 SLC23A2 9962 solute carrier family 23 (ascorbic acid transporter), member 2 basolateral plasma membrane Cellular component 15993839 IL9 3578 interleukin 9 positive regulation of cell growth Biological process - SDS 10993 serine dehydratase L-serine catabolic process Biological process 15689518 HIST1H3C 8352 histone cluster 1, H3c nucleosome assembly Biological process 25615412 HIST1H2BN 8341 histone cluster 1, H2bn nucleoplasm Cellular component - GATA2 2624 GATA binding protein 2 RNA polymerase II distal enhancer sequence-specific DNA binding Molecular function - GPR45 11250 G protein-coupled receptor 45 G-protein coupled receptor activity Molecular function - GCDH 2639 glutaryl-CoA dehydrogenase mitochondrion Cellular component - RARA 5914 retinoic acid receptor, alpha nucleus Cellular component - NUP214 8021 nucleoporin 214kDa protein export from nucleus Biological process 12191473 C9orf9 11092 chromosome 9 open reading frame 9 acrosomal vesicle Cellular component - GPM6B 2824 glycoprotein M6B ossification Biological process - SLC2A2 6514 solute carrier family 2 (facilitated glucose transporter), member 2 dehydroascorbic acid transporter activity Molecular function - SST 6750 somatostatin negative regulation of cell proliferation Biological process 9886848 TRPC5 7224 transient receptor potential cation channel, subfamily C, member 5 ion transmembrane transport Biological process - WNT5A 7474 wingless-type MMTV integration site family, member 5A embryonic digit morphogenesis Biological process - MBL2 4153 mannose-binding lectin (protein C) 2, soluble complement activation, classical pathway Biological process - MRPL17 63875 mitochondrial ribosomal protein L17 mitochondrial translation Biological process - TMC6 11322 transmembrane channel-like 6 cytoplasm Cellular component 12426567 MMP1 4312 matrix metallopeptidase 1 leukocyte migration Biological process - AKAP8 10270 A kinase (PRKA) anchor protein 8 nucleoplasm Cellular component - TYROBP 7305 TYRO protein tyrosine kinase binding protein integrin-mediated signaling pathway Biological process - PRNP 5621 prion protein protein homooligomerization Biological process - PPAP2A 8611 phosphatidic acid phosphatase type 2A negative regulation of cell proliferation Biological process 9468526 YBX1 4904 Y box binding protein 1 RNA binding Molecular function 19561594 USP18 11274 ubiquitin specific peptidase 18 nucleus Cellular component - TUBB2B 347733 tubulin, beta 2B class IIb GTP binding Molecular function - TDRD9 122402 tudor domain containing 9 P granule Cellular component - APOBEC1 339 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 response to gamma radiation Biological process - MED12 9968 mediator complex subunit 12 RNA polymerase II transcription cofactor activity Molecular function 10198638 TUB 7275 tubby bipartite transcription factor protein complex binding Molecular function 20889716 CREB3L3 84699 cAMP responsive element binding protein 3-like 3 transcription, DNA-templated Biological process - AKIRIN1 79647 akirin 1 protein binding Molecular function 25416956 ACTL6B 51412 actin-like 6B transcription coactivator activity Molecular function 8804307 IP6K3 117283 inositol hexakisphosphate kinase 3 phosphatidylinositol metabolic process Biological process 11502751 CDH1 999 cadherin 1, type 1, E-cadherin (epithelial) cell junction Cellular component 17047063 MCM7 4176 minichromosome maintenance complex component 7 DNA replication initiation Biological process - PTH2R 5746 parathyroid hormone 2 receptor plasma membrane Cellular component - RAB9A 9367 RAB9A, member RAS oncogene family extracellular exosome Cellular component 20458337 CYP7B1 9420 cytochrome P450, family 7, subfamily B, polypeptide 1 positive regulation of epithelial cell proliferation Biological process - FRG2 448831 FSHD region gene 2 nucleus Cellular component - ADPGK 83440 ADP-dependent glucokinase glycolytic process Biological process - AMDHD2 51005 amidohydrolase domain containing 2 protein binding Molecular function 25416956 FLOT2 2319 flotillin 2 negative regulation of gene expression Biological process 24612608 SHPRH 257218 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase DNA binding Molecular function - PRLHR 2834 prolactin releasing hormone receptor plasma membrane Cellular component - RAB3A 5864 RAB3A, member RAS oncogene family plasma membrane Cellular component - SLC7A1 6541 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 plasma membrane Cellular component - PDE8B 8622 phosphodiesterase 8B cytosol Cellular component - TGFBR1 7046 transforming growth factor, beta receptor 1 neuron fate commitment Biological process - SSC5D 284297 scavenger receptor cysteine rich family, 5 domains innate immune response Biological process - NYAP2 57624 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2 protein binding Molecular function 25416956 PMS1 5378 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) mismatch repair Biological process - GBAS 2631 glioblastoma amplified sequence ATP biosynthetic process Biological process 20888800 RBX1 9978 ring-box 1, E3 ubiquitin protein ligase ubiquitin-protein transferase activity Molecular function 15983046 DISP1 84976 dispatched homolog 1 (Drosophila) peptide transporter activity Molecular function - SLC8A1 6546 solute carrier family 8 (sodium/calcium exchanger), member 1 positive regulation of bone mineralization Biological process 25589784 TP53 7157 tumor protein p53 neuron apoptotic process Biological process - UFC1 51506 ubiquitin-fold modifier conjugating enzyme 1 response to endoplasmic reticulum stress Biological process 23152784 ANK3 288 ankyrin 3, node of Ranvier (ankyrin G) lateral plasma membrane Cellular component 14757759 MVB12B 89853 multivesicular body subunit 12B extracellular exosome Cellular component 19056867 ATP1B1 481 ATPase, Na+/K+ transporting, beta 1 polypeptide cardiac muscle contraction Biological process - CD46 4179 CD46 molecule, complement regulatory protein focal adhesion Cellular component 21423176 NQO1 1728 NAD(P)H dehydrogenase, quinone 1 cellular nitrogen compound metabolic process Biological process - CNDP1 84735 carnosine dipeptidase 1 (metallopeptidase M20 family) tripeptidase activity Molecular function - DRD2 1813 dopamine receptor D2 intracellular Cellular component 1331329 CHRNA1 1134 cholinergic receptor, nicotinic, alpha 1 (muscle) neuronal action potential Biological process 8872460 EOMES 8320 eomesodermin brain development Biological process 17353897 ATCAY 85300 ataxia, cerebellar, Cayman type synapse Cellular component - CYP2C9 1559 cytochrome P450, family 2, subfamily C, polypeptide 9 monocarboxylic acid metabolic process Biological process 19651758 SPEF2 79925 sperm flagellar 2 multicellular organismal aging Biological process - CCNA1 8900 cyclin A1 G1/S transition of mitotic cell cycle Biological process - BMP4 652 bone morphogenetic protein 4 chondrocyte differentiation Biological process - STAM 8027 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 membrane organization Biological process - CPNE3 8895 copine III cytoplasm Cellular component 11041869 RBM17 84991 RNA binding motif protein 17 alternative mRNA splicing, via spliceosome Biological process 17589525 CLDN23 137075 claudin 23 bicellular tight junction Cellular component - RPS3 6188 ribosomal protein S3 negative regulation of DNA repair Biological process 17049931 FAF1 11124 Fas (TNFRSF6) associated factor 1 nuclear envelope Cellular component - TBX1 6899 T-box 1 protein dimerization activity Molecular function 17273972 ADORA2A 135 adenosine A2a receptor enzyme binding Molecular function 16339847 TOB2 10766 transducer of ERBB2, 2 protein binding Molecular function 23340509 POLR2E 5434 polymerase (RNA) II (DNA directed) polypeptide E, 25kDa transcription elongation from RNA polymerase III promoter Biological process - GRM7 2917 glutamate receptor, metabotropic 7 serine binding Molecular function 9144652 SLC7A5 8140 solute carrier family 7 (amino acid transporter light chain, L system), member 5 neutral amino acid transport Biological process - SEC22A 26984 SEC22 vesicle trafficking protein homolog A (S. cerevisiae) transporter activity Molecular function 8621431 HNRNPH1 3187 heterogeneous nuclear ribonucleoprotein H1 (H) gene expression Biological process - MAN1B1 11253 mannosidase, alpha, class 1B, member 1 endoplasmic reticulum Cellular component 18003979 HVCN1 84329 hydrogen voltage gated channel 1 cellular response to pH Biological process 22020278 COG3 83548 component of oligomeric golgi complex 3 cis-Golgi network Cellular component - HNRNPA3 220988 heterogeneous nuclear ribonucleoprotein A3 mRNA splicing, via spliceosome Biological process - MARK3 4140 MAP/microtubule affinity-regulating kinase 3 plasma membrane Cellular component 21145462 PLA2G4D 283748 phospholipase A2, group IVD (cytosolic) cytoplasmic vesicle membrane Cellular component - GRIN1 2902 glutamate receptor, ionotropic, N-methyl D-aspartate 1 regulation of synapse assembly Biological process - FIGF 2277 c-fos induced growth factor (vascular endothelial growth factor D) vascular endothelial growth factor receptor signaling pathway Biological process - WNT3A 89780 wingless-type MMTV integration site family, member 3A extracellular matrix organization Biological process - MAP3K8 1326 mitogen-activated protein kinase kinase kinase 8 cytoplasm Cellular component - IQGAP3 128239 IQ motif containing GTPase activating protein 3 Ras protein signal transduction Biological process - CXCR4 7852 chemokine (C-X-C motif) receptor 4 dendritic cell chemotaxis Biological process 16621978 HSPA5 3309 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) glycoprotein binding Molecular function 20477988 CTSV 1515 cathepsin V autophagic cell death Biological process - SLC27A5 10998 solute carrier family 27 (fatty acid transporter), member 5 bile acid biosynthetic process Biological process - GPM6B 2824 glycoprotein M6B nervous system development Biological process 8661015 ZMYM2 7750 zinc finger, MYM-type 2 transcription, DNA-templated Biological process - FOXR1 283150 forkhead box R1 transcription from RNA polymerase II promoter Biological process - MUC6 4588 mucin 6, oligomeric mucus/gel-forming post-translational protein modification Biological process - PLEKHF2 79666 pleckstrin homology domain containing, family F (with FYVE domain) member 2 metal ion binding Molecular function - PRSS3 5646 protease, serine, 3 extracellular space Cellular component 6698368 GTSE1 51512 G-2 and S-phase expressed 1 cytoplasmic microtubule Cellular component 10974554 TMPRSS6 164656 transmembrane protease, serine 6 negative regulation of transcription, DNA-templated Biological process 25156943 ZSWIM5 57643 zinc finger, SWIM-type containing 5 zinc ion binding Molecular function - F5 2153 coagulation factor V (proaccelerin, labile factor) Golgi apparatus Cellular component - DDX3Y 8653 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked ATP binding Molecular function - SNCB 6620 synuclein, beta dopamine metabolic process Biological process - PLEC 5339 plectin poly(A) RNA binding Molecular function 22658674 MAPK1 5594 mitogen-activated protein kinase 1 positive regulation of translation Biological process - KCNJ5 3762 potassium channel, inwardly rectifying subfamily J, member 5 plasma membrane Cellular component - PDK3 5165 pyruvate dehydrogenase kinase, isozyme 3 ATP binding Molecular function 15861126 GAD2 2572 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) response to drug Biological process - NRXN2 9379 neurexin 2 transmembrane signaling receptor activity Molecular function 18923512 CYB5R3 1727 cytochrome b5 reductase 3 mitochondrial inner membrane Cellular component - BRSK1 84446 BR serine/threonine kinase 1 neuron differentiation Biological process - PLCD4 84812 phospholipase C, delta 4 phosphatidylinositol phospholipase C activity Molecular function - XDH 7498 xanthine dehydrogenase xanthine dehydrogenase activity Molecular function 8670112 CHMP1B 57132 charged multivesicular body protein 1B cytosol Cellular component - ADGRA3 166647 adhesion G protein-coupled receptor A3 G-protein coupled receptor signaling pathway Biological process - ACAP3 116983 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 positive regulation of GTPase activity Biological process - HLA-C 3107 major histocompatibility complex, class I, C regulation of immune response Biological process - DMRTC2 63946 DMRT-like family C2 sex differentiation Biological process - MCL1 4170 myeloid cell leukemia 1 multicellular organismal development Biological process - CHML 1122 choroideremia-like (Rab escort protein 2) protein geranylgeranylation Biological process 12356470 CCNT1 904 cyclin T1 transcription regulatory region DNA binding Molecular function - NRXN1 9378 neurexin 1 extracellular matrix organization Biological process - DDX43 55510 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 intracellular Cellular component - KIF2C 11004 kinesin family member 2C ATPase activity Molecular function - CRMP1 1400 collapsin response mediator protein 1 neuronal cell body Cellular component - CHIC1 53344 cysteine-rich hydrophobic domain 1 cytoplasmic membrane-bounded vesicle Cellular component - TSKU 25987 tsukushi, small leucine rich proteoglycan extracellular space Cellular component - UFD1L 7353 ubiquitin fusion degradation 1 like (yeast) ubiquitin-dependent protein catabolic process Biological process 9063746 TRIM14 9830 tripartite motif containing 14 negative regulation of viral transcription Biological process 18248090 PKN1 5585 protein kinase N1 protein binding Molecular function 12761180 GHRHR 2692 growth hormone releasing hormone receptor nuclear matrix Cellular component 10461027 KIAA0141 9812 KIAA0141 protein binding Molecular function 20563667 ASAP3 55616 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 metal ion binding Molecular function - IRX5 10265 iroquois homeobox 5 response to stimulus Biological process - CHMP2B 25978 charged multivesicular body protein 2B cytosol Cellular component - OR8J3 81168 olfactory receptor, family 8, subfamily J, member 3 olfactory receptor activity Molecular function - TAF1L 138474 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like protein serine/threonine kinase activity Molecular function 12217962 PITPNM1 9600 phosphatidylinositol transfer protein, membrane-associated 1 cleavage furrow Cellular component - WNT7A 7476 wingless-type MMTV integration site family, member 7A synapse organization Biological process - GYPC 2995 glycophorin C (Gerbich blood group) membrane Cellular component 19946888 SPNS2 124976 spinster homolog 2 (Drosophila) integral component of membrane Cellular component - SOX8 30812 SRY (sex determining region Y)-box 8 nuclear transcription factor complex Cellular component - H2AFY 9555 H2A histone family, member Y protein binding Molecular function 22391447 NUP88 4927 nucleoporin 88kDa carbohydrate metabolic process Biological process - OR51D1 390038 olfactory receptor, family 51, subfamily D, member 1 integral component of membrane Cellular component - FOSL2 2355 FOS-like antigen 2 nucleoplasm Cellular component - URAD 646625 ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase cellular_component Cellular component - DNM1L 10059 dynamin 1-like mitochondrial membrane fission Biological process 11514614 CHUK 1147 conserved helix-loop-helix ubiquitous kinase cytoplasmic side of plasma membrane Cellular component - TTLL3 26140 tubulin tyrosine ligase-like family member 3 microtubule Cellular component - DGKD 8527 diacylglycerol kinase, delta 130kDa endocytosis Biological process - GPN2 54707 GPN-loop GTPase 2 GTP binding Molecular function - ZNF335 63925 zinc finger protein 335 regulation of histone H3-K4 methylation Biological process - RFWD2 64326 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase positive regulation of proteasomal ubiquitin-dependent protein catabolic process Biological process 19805145 HIST1H2BM 8342 histone cluster 1, H2bm nucleosome Cellular component 9439656 CCL2 6347 chemokine (C-C motif) ligand 2 axon terminus Cellular component - SERP1 27230 stress-associated endoplasmic reticulum protein 1 positive regulation of insulin secretion Biological process - CCNB2 9133 cyclin B2 microtubule cytoskeleton Cellular component - LIMK1 3984 LIM domain kinase 1 focal adhesion Cellular component - ACACA 31 acetyl-CoA carboxylase alpha nucleolus Cellular component - CD44 960 CD44 molecule (Indian blood group) focal adhesion Cellular component 21423176 SLC25A27 9481 solute carrier family 25, member 27 mitochondrion Cellular component 10025957 SPARCL1 8404 SPARC-like 1 (hevin) extracellular space Cellular component 16502470 FCN3 8547 ficolin (collagen/fibrinogen domain containing) 3 blood microparticle Cellular component 22516433 DVL2 1856 dishevelled segment polarity protein 2 cytosol Cellular component - FAM160A2 84067 family with sequence similarity 160, member A2 early endosome to late endosome transport Biological process 18799622 CD44 960 CD44 molecule (Indian blood group) basolateral plasma membrane Cellular component - UCKL1 54963 uridine-cytidine kinase 1-like 1 nucleus Cellular component - GPR15 2838 G protein-coupled receptor 15 T cell migration Biological process - BST2 684 bone marrow stromal cell antigen 2 B cell activation Biological process - FAM162A 26355 family with sequence similarity 162, member A cytoplasm Cellular component - LRRTM1 347730 leucine rich repeat transmembrane neuronal 1 negative regulation of receptor internalization Biological process - CRY2 1408 cryptochrome circadian clock 2 damaged DNA binding Molecular function 12627958 GNAQ 2776 guanine nucleotide binding protein (G protein), q polypeptide phospholipase C-activating dopamine receptor signaling pathway Biological process - QKI 9444 QKI, KH domain containing, RNA binding regulation of translation Biological process - LRRTM1 347730 leucine rich repeat transmembrane neuronal 1 cell surface Cellular component 17667961 NR1D1 9572 nuclear receptor subfamily 1, group D, member 1 dendritic spine Cellular component - NPNT 255743 nephronectin cell-cell adhesion mediated by integrin Biological process 15754038 IL1B 3553 interleukin 1, beta stimulatory C-type lectin receptor signaling pathway Biological process - USP42 84132 ubiquitin specific peptidase 42 protein deubiquitination Biological process - ICAM2 3384 intercellular adhesion molecule 2 membrane Cellular component 19946888 FBXO18 84893 F-box protein, helicase, 18 DNA binding Molecular function - LOC391742 391742 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa pseudogene transcription initiation from RNA polymerase II promoter Biological process - ATP6V1G3 127124 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 plasma membrane Cellular component 17360703 SRSF6 6431 serine/arginine-rich splicing factor 6 regulation of wound healing Biological process 24440982 ANK2 287 ankyrin 2, neuronal protein localization to plasma membrane Biological process - MNX1 3110 motor neuron and pancreas homeobox 1 sequence-specific DNA binding transcription factor activity Molecular function 9843207 MX2 4600 MX dynamin-like GTPase 2 cytosol Cellular component - CACNG8 59283 calcium channel, voltage-dependent, gamma subunit 8 calcium ion transmembrane transport Biological process - PLAU 5328 plasminogen activator, urokinase serine-type endopeptidase activity Molecular function - TBX15 6913 T-box 15 protein heterodimerization activity Molecular function - TNFSF10 8743 tumor necrosis factor (ligand) superfamily, member 10 regulation of extrinsic apoptotic signaling pathway via death domain receptors Biological process - HPS1 3257 Hermansky-Pudlak syndrome 1 protein dimerization activity Molecular function 12663659 RGS13 6003 regulator of G-protein signaling 13 cytoplasm Cellular component - XYLT2 64132 xylosyltransferase II protein xylosyltransferase activity Molecular function 11099377 MKL1 57591 megakaryoblastic leukemia (translocation) 1 nucleus Cellular component 14970199 DAPK2 23604 death-associated protein kinase 2 identical protein binding Molecular function 10629061 TCP11 6954 t-complex 11, testis-specific spermatogenesis Biological process - TAP2 6891 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) protein binding Molecular function 12213826 ADCY9 115 adenylate cyclase 9 integral component of plasma membrane Cellular component 9628827 IP6K3 117283 inositol hexakisphosphate kinase 3 small molecule metabolic process Biological process - HNRNPL 3191 heterogeneous nuclear ribonucleoprotein L RNA binding Molecular function 2687284 RPS17 6218 ribosomal protein S17 cytosol Cellular component - IKBKG 8517 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process - KLKB1 3818 kallikrein B, plasma (Fletcher factor) 1 extracellular space Cellular component 89876 ZNF324B 388569 zinc finger protein 324B regulation of transcription, DNA-templated Biological process - IL18R1 8809 interleukin 18 receptor 1 natural killer cell activation Biological process - CRACR2A 84766 calcium release activated channel regulator 2A membrane Cellular component 19946888 PHF21A 51317 PHD finger protein 21A negative regulation of transcription from RNA polymerase II promoter Biological process 15325272 IKZF3 22806 IKAROS family zinc finger 3 (Aiolos) metal ion binding Molecular function - DSC2 1824 desmocollin 2 regulation of heart rate by cardiac conduction Biological process 23863954 ALAS2 212 5'-aminolevulinate synthase 2 hemoglobin biosynthetic process Biological process - AGO2 27161 argonaute RISC catalytic component 2 gene expression Biological process - ADRB2 154 adrenoceptor beta 2, surface apical plasma membrane Cellular component - PRDX1 5052 peroxiredoxin 1 protein homodimerization activity Molecular function - PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide platelet activating factor receptor activity Molecular function 2536956 STAR 6770 steroidogenic acute regulatory protein cellular response to growth hormone stimulus Biological process - PPIF 10105 peptidylprolyl isomerase F cellular response to calcium ion Biological process - BCL3 602 B-cell CLL/lymphoma 3 protein complex Cellular component 16280327 BAD 572 BCL2-associated agonist of cell death positive regulation of T cell differentiation Biological process - SYT9 143425 synaptotagmin IX calcium ion binding Molecular function - AKR1C3 8644 aldo-keto reductase family 1, member C3 positive regulation of protein kinase B signaling Biological process 18508192 PCNT 5116 pericentrin ciliary basal body Cellular component - ATP9A 10079 ATPase, class II, type 9A metabolic process Biological process - HDAC2 3066 histone deacetylase 2 nuclear chromatin Cellular component 16217013 HCN2 610 hyperpolarization activated cyclic nucleotide gated potassium channel 2 identical protein binding Molecular function 22006928 OOEP 441161 oocyte expressed protein protein phosphorylation Biological process - PSMB5 5693 proteasome (prosome, macropain) subunit, beta type, 5 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - S100A14 57402 S100 calcium binding protein A14 calcium ion homeostasis Biological process 16682778 CREBL2 1389 cAMP responsive element binding protein-like 2 nucleus Cellular component - ATP13A2 23400 ATPase type 13A2 cellular response to manganese ion Biological process 23628791 DAB2IP 153090 DAB2 interacting protein negative regulation of vascular endothelial growth factor signaling pathway Biological process - F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 plasma membrane Cellular component - NPAS4 266743 neuronal PAS domain protein 4 nucleus Cellular component - JARID2 3720 jumonji, AT rich interactive domain 2 gene expression Biological process - EFNB1 1947 ephrin-B1 neural crest cell migration Biological process - LHX9 56956 LIM homeobox 9 negative regulation of transcription, DNA-templated Biological process - MYOD1 4654 myogenic differentiation 1 protein heterodimerization activity Molecular function - COL11A1 1301 collagen, type XI, alpha 1 protein binding, bridging Molecular function 10486316 PAPSS2 9060 3'-phosphoadenosine 5'-phosphosulfate synthase 2 carbohydrate metabolic process Biological process - GPR150 285601 G protein-coupled receptor 150 G-protein coupled receptor activity Molecular function - AP2A2 161 adaptor-related protein complex 2, alpha 2 subunit cytosol Cellular component - CUBN 8029 cubilin (intrinsic factor-cobalamin receptor) small molecule metabolic process Biological process - SLC5A9 200010 solute carrier family 5 (sodium/sugar cotransporter), member 9 extracellular exosome Cellular component 19056867 HP1BP3 50809 heterochromatin protein 1, binding protein 3 protein binding Molecular function 20042602 SNX17 9784 sorting nexin 17 cytoplasmic vesicle membrane Cellular component - SMOC2 64094 SPARC related modular calcium binding 2 signal transduction Biological process - ZNFX1 57169 zinc finger, NFX1-type containing 1 poly(A) RNA binding Molecular function 22658674 MED8 112950 mediator complex subunit 8 nucleoplasm Cellular component - TRPV4 59341 transient receptor potential cation channel, subfamily V, member 4 SH2 domain binding Molecular function - SF3B6 51639 splicing factor 3b, subunit 6, 14kDa nucleotide binding Molecular function - NOTCH1 4851 notch 1 negative regulation of cell migration involved in sprouting angiogenesis Biological process 20616313 OAS1 4938 2'-5'-oligoadenylate synthetase 1, 40/46kDa regulation of ribonuclease activity Biological process 19923450 SENP2 59343 SUMO1/sentrin/SMT3 specific peptidase 2 protein binding Molecular function 11896061 PPME1 51400 protein phosphatase methylesterase 1 negative regulation of catalytic activity Biological process 10318862 MSR1 4481 macrophage scavenger receptor 1 positive regulation of cholesterol storage Biological process - APBA2 321 amyloid beta (A4) precursor protein-binding, family A, member 2 synaptic vesicle Cellular component - OCRL 4952 oculocerebrorenal syndrome of Lowe inositol phosphate phosphatase activity Molecular function 1321346 NOTCH1 4851 notch 1 glomerular mesangial cell development Biological process - NUP107 57122 nucleoporin 107kDa nucleocytoplasmic transporter activity Molecular function 11684705 MKS1 54903 Meckel syndrome, type 1 centrosome Cellular component 19208769 BMP2 650 bone morphogenetic protein 2 BMP signaling pathway involved in heart induction Biological process 19736317 ATF6 22926 activating transcription factor 6 nucleoplasm Cellular component - C1QTNF1 114897 C1q and tumor necrosis factor related protein 1 protein binding Molecular function 12409230 LAMC2 3918 laminin, gamma 2 hemidesmosome assembly Biological process - RHOBTB3 22836 Rho-related BTB domain containing 3 Rab GTPase binding Molecular function 19490898 VPS16 64601 vacuolar protein sorting 16 homolog (S. cerevisiae) axon Cellular component - CCDC137 339230 coiled-coil domain containing 137 nucleolus Cellular component - PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta fibroblast growth factor receptor signaling pathway Biological process - DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) apical plasma membrane Cellular component - INS 3630 insulin positive regulation of glycogen biosynthetic process Biological process 17925406 ZXDA 7789 zinc finger, X-linked, duplicated A metal ion binding Molecular function - CUX1 1523 cut-like homeobox 1 transcription, DNA-templated Biological process - HYAL2 8692 hyaluronoglucosaminidase 2 viral entry into host cell Biological process - CDC42EP1 11135 CDC42 effector protein (Rho GTPase binding) 1 Golgi apparatus Cellular component - CD209 30835 CD209 molecule protein binding Molecular function 12609975 GGCT 79017 gamma-glutamylcyclotransferase protein homodimerization activity Molecular function 17932939 OR52E2 119678 olfactory receptor, family 52, subfamily E, member 2 G-protein coupled receptor signaling pathway Biological process - ITGA4 3676 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) B cell differentiation Biological process 1715889 STMN2 11075 stathmin 2 axon Cellular component - MAGEF1 64110 melanoma antigen family F1 protein binding Molecular function 25416956 AURKA 6790 aurora kinase A anterior/posterior axis specification Biological process - RPS6KB1 6198 ribosomal protein S6 kinase, 70kDa, polypeptide 1 cell junction Cellular component - FOXJ1 2302 forkhead box J1 epithelium development Biological process 9073514 NF1 4763 neurofibromin 1 negative regulation of protein kinase activity Biological process - GHSR 2693 growth hormone secretagogue receptor decidualization Biological process 17494105 GBF1 8729 golgi brefeldin A resistant guanine nucleotide exchange factor 1 protein localization to endoplasmic reticulum tubular network Biological process 17956946 RASD2 23551 RASD family, member 2 plasma membrane Cellular component - TYR 7299 tyrosinase protein homodimerization activity Molecular function - CCDC39 339829 coiled-coil domain containing 39 axoneme Cellular component 21131972 RBCK1 10616 RanBP-type and C3HC4-type zinc finger containing 1 positive regulation of NF-kappaB transcription factor activity Biological process 19136968 DDX52 11056 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 nucleolus Cellular component - FRY 10129 furry homolog (Drosophila) microtubule organizing center Cellular component - FOXP3 50943 forkhead box P3 negative regulation of T-helper 17 cell differentiation Biological process 23169781 CYP2D6 1565 cytochrome P450, family 2, subfamily D, polypeptide 6 drug catabolic process Biological process 15039299 HNRNPF 3185 heterogeneous nuclear ribonucleoprotein F poly(A) RNA binding Molecular function 22658674 USP48 84196 ubiquitin specific peptidase 48 cysteine-type endopeptidase activity Molecular function - TPP2 7174 tripeptidyl peptidase II aminopeptidase activity Molecular function - CIDEB 27141 cell death-inducing DFFA-like effector b lipid particle Cellular component - SLC25A13 10165 solute carrier family 25 (aspartate/glutamate carrier), member 13 L-aspartate transmembrane transporter activity Molecular function 11566871 ING2 3622 inhibitor of growth family, member 2 regulation of transcription, DNA-templated Biological process 15243141 PRKAR2B 5577 protein kinase, cAMP-dependent, regulatory, type II, beta energy reserve metabolic process Biological process - RPP38 10557 ribonuclease P/MRP 38kDa subunit RNA phosphodiester bond hydrolysis, endonucleolytic Biological process 9630247 DIRAS2 54769 DIRAS family, GTP-binding RAS-like 2 GTP binding Molecular function 12194967 EDNRB 1910 endothelin receptor type B integral component of plasma membrane Cellular component 8810293 AIMP1 9255 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 tRNA binding Molecular function 11306575 CRYGD 1421 crystallin, gamma D protein binding Molecular function 22289178 IL12A 3592 interleukin 12A response to virus Biological process 16548883 CYP1B1 1545 cytochrome P450, family 1, subfamily B, polypeptide 1 monooxygenase activity Molecular function 9097971 ERVK-26 103539957 endogenous retrovirus group K, member 26 RNA binding Molecular function - MSX2 4488 msh homeobox 2 anterior/posterior pattern specification Biological process - HDAC9 9734 histone deacetylase 9 nucleoplasm Cellular component - SLC28A2 9153 solute carrier family 28 (concentrative nucleoside transporter), member 2 purine nucleoside transmembrane transporter activity Molecular function 9435697 GATA3 2625 GATA binding protein 3 transcription from RNA polymerase II promoter Biological process 1871134 DDX3X 1654 DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked DNA duplex unwinding Biological process 21589879 SEMA5A 9037 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A positive regulation of endothelial cell chemotaxis Biological process - SNAP23 8773 synaptosomal-associated protein, 23kDa synapse Cellular component - CDC25B 994 cell division cycle 25B mitotic cell cycle Biological process 9188863 ZNF582 147948 zinc finger protein 582 DNA binding Molecular function - SNRPE 6635 small nuclear ribonucleoprotein polypeptide E nucleus Cellular component 23246290 UTS2 10911 urotensin 2 negative regulation of urine volume Biological process - TSR3 115939 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) maturation of SSU-rRNA Biological process - ZC3H12D 340152 zinc finger CCCH-type containing 12D cytoplasm Cellular component 19531561 SKAP2 8935 src kinase associated phosphoprotein 2 plasma membrane Cellular component 11390434 PLEKHA1 59338 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 luteinization Biological process - CMPK1 51727 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic cytosol Cellular component - SLC16A13 201232 solute carrier family 16, member 13 monocarboxylic acid transmembrane transporter activity Molecular function - GGTLC2 91227 gamma-glutamyltransferase light chain 2 leukotriene biosynthetic process Biological process - SETD7 80854 SET domain containing (lysine methyltransferase) 7 nucleolus Cellular component - FCGR2B 2213 Fc fragment of IgG, low affinity IIb, receptor (CD32) protein binding Molecular function 10382761 FZD7 8324 frizzled class receptor 7 protein binding Molecular function 18256285 VDR 7421 vitamin D (1,25- dihydroxyvitamin D3) receptor transcription initiation from RNA polymerase II promoter Biological process - DAZ2 57055 deleted in azoospermia 2 cell differentiation Biological process - NODAL 4838 nodal growth differentiation factor extracellular space Cellular component 21656830 FOXL1 2300 forkhead box L1 proteoglycan biosynthetic process Biological process - REG1B 5968 regenerating islet-derived 1 beta carbohydrate binding Molecular function - CDR2 1039 cerebellar degeneration-related protein 2, 62kDa cytoplasm Cellular component - KIZ 55857 kizuna centrosomal protein protein kinase binding Molecular function 16980960 RPS6KB1 6198 ribosomal protein S6 kinase, 70kDa, polypeptide 1 signal transduction Biological process 1922062 ARIH1 25820 ariadne RBR E3 ubiquitin protein ligase 1 ubiquitin protein ligase binding Molecular function 11278816 DZIP1 22873 DAZ interacting zinc finger protein 1 nucleus Cellular component 15081113 ANAPC10 10393 anaphase promoting complex subunit 10 mitotic cell cycle Biological process - FOXG1 2290 forkhead box G1 positive regulation of neuroblast proliferation Biological process - COX6C 1345 cytochrome c oxidase subunit VIc cellular metabolic process Biological process - PSMB8 5696 proteasome (prosome, macropain) subunit, beta type, 8 proteasome-mediated ubiquitin-dependent protein catabolic process Biological process - PF4 5196 platelet factor 4 G-protein coupled receptor signaling pathway Biological process - HNF4A 3172 hepatocyte nuclear factor 4, alpha DNA binding Molecular function 10551874 ZNF880 400713 zinc finger protein 880 intracellular Cellular component - GNS 2799 glucosamine (N-acetyl)-6-sulfatase protein binding Molecular function 17474147 ZNF136 7695 zinc finger protein 136 transcription from RNA polymerase II promoter Biological process 7649249 KDELR2 11014 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 intracellular protein transport Biological process 1325562 PEG3 5178 paternally expressed 3 apoptotic process Biological process - PDCD6IP 10015 programmed cell death 6 interacting protein endoplasmic reticulum exit site Cellular component 16957052 TTYH1 57348 tweety family member 1 iron ion transmembrane transport Biological process 10950931 SSTR3 6753 somatostatin receptor 3 cell-cell signaling Biological process 1337145 NRIP1 8204 nuclear receptor interacting protein 1 histone deacetylase complex Cellular component - OPN1MW 2652 opsin 1 (cone pigments), medium-wave-sensitive visual perception Biological process - LAMA1 284217 laminin, alpha 1 cell-cell junction Cellular component - MYH9 4627 myosin, heavy chain 9, non-muscle focal adhesion Cellular component - MAPK1 5594 mitogen-activated protein kinase 1 cellular response to DNA damage stimulus Biological process - MMP20 9313 matrix metallopeptidase 20 extracellular matrix organization Biological process - LCN1 3933 lipocalin 1 sensory perception of taste Biological process - BHLHB9 80823 basic helix-loop-helix domain containing, class B, 9 positive regulation of dendritic spine morphogenesis Biological process - HLA-DQB1 3119 major histocompatibility complex, class II, DQ beta 1 lysosomal membrane Cellular component - AHI1 54806 Abelson helper integration site 1 regulation of behavior Biological process - GRIN2C 2905 glutamate receptor, ionotropic, N-methyl D-aspartate 2C ionotropic glutamate receptor signaling pathway Biological process - PSMB6 5694 proteasome (prosome, macropain) subunit, beta type, 6 antigen processing and presentation of exogenous peptide antigen via MHC class I Biological process - CCNC 892 cyclin C transcription, DNA-templated Biological process - CSTF2 1478 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa mRNA cleavage Biological process 1741396 SERPINB9 5272 serpin peptidase inhibitor, clade B (ovalbumin), member 9 response to bacterium Biological process 22090449 HECTD3 79654 HECT domain containing E3 ubiquitin protein ligase 3 protein binding Molecular function 18194665 OAS1 4938 2'-5'-oligoadenylate synthetase 1, 40/46kDa mitochondrion Cellular component - FEZF1 389549 FEZ family zinc finger 1 olfactory bulb development Biological process - ZNF563 147837 zinc finger protein 563 regulation of transcription, DNA-templated Biological process - H2AFB1 474382 H2A histone family, member B1 nucleosome assembly Biological process 22795134 KDM6A 7403 lysine (K)-specific demethylase 6A oxidation-reduction process Biological process - AKAP6 9472 A kinase (PRKA) anchor protein 6 protein complex scaffold Molecular function - INHBA 3624 inhibin, beta A positive regulation of cellular protein metabolic process Biological process 21828274 GADD45GIP1 90480 growth arrest and DNA-damage-inducible, gamma interacting protein 1 mitochondrial translational elongation Biological process - SLX1B 79008 SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) Slx1-Slx4 complex Cellular component 19595721 CCKBR 887 cholecystokinin B receptor cholecystokinin receptor activity Molecular function 7681836 DPF2 5977 D4, zinc and double PHD fingers family 2 apoptotic process Biological process 8812431 NKX6-1 4825 NK6 homeobox 1 smoothened signaling pathway Biological process - FLRT3 23767 fibronectin leucine rich transmembrane protein 3 extracellular space Cellular component - CDKN2D 1032 cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage Biological process 15750620 PSMB2 5690 proteasome (prosome, macropain) subunit, beta type, 2 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - SOX15 6665 SRY (sex determining region Y)-box 15 nucleus Cellular component 8332506 PDPN 10630 podoplanin amino acid transmembrane transporter activity Molecular function - FSTL3 10272 follistatin-like 3 (secreted glycoprotein) secretory granule Cellular component - ID3 3399 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein regulation of DNA replication Biological process - KCNQ1 3784 potassium channel, voltage gated KQT-like subfamily Q, member 1 voltage-gated potassium channel complex Cellular component 16002409 DHRS13 147015 dehydrogenase/reductase (SDR family) member 13 oxidoreductase activity Molecular function - WDR82 80335 WD repeat domain 82 chromatin binding Molecular function - G6PC2 57818 glucose-6-phosphatase, catalytic, 2 integral component of endoplasmic reticulum membrane Cellular component - UCHL1 7345 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) ligase activity Molecular function - PDE4DIP 9659 phosphodiesterase 4D interacting protein cellular protein complex assembly Biological process 11134006 SBK1 388228 SH3 domain binding kinase 1 ATP binding Molecular function - KIF21A 55605 kinesin family member 21A microtubule motor activity Molecular function - SLC4A5 57835 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 transmembrane transport Biological process - UBE2B 7320 ubiquitin-conjugating enzyme E2B negative regulation of apoptotic process Biological process - FKBP14 55033 FK506 binding protein 14, 22 kDa endoplasmic reticulum membrane Cellular component - CTGF 1490 connective tissue growth factor protein binding Molecular function 16457822 HLA-DQB2 3120 major histocompatibility complex, class II, DQ beta 2 endocytic vesicle membrane Cellular component - CADM1 23705 cell adhesion molecule 1 PDZ domain binding Molecular function 12826663 BRCA1 672 breast cancer 1, early onset positive regulation of histone H3-K9 acetylation Biological process 20820192 POFUT1 23509 protein O-fucosyltransferase 1 endoplasmic reticulum Cellular component 15653671 HNRNPH2 3188 heterogeneous nuclear ribonucleoprotein H2 (H') nucleoplasm Cellular component - DTNBP1 84062 dystrobrevin binding protein 1 regulation of dopamine receptor signaling pathway Biological process - PLCH1 23007 phospholipase C, eta 1 signal transducer activity Molecular function - PLAU 5328 plasminogen activator, urokinase signal transduction Biological process 10749881 STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) plasma membrane Cellular component - PF4 5196 platelet factor 4 positive regulation of cAMP-mediated signaling Biological process 12782716 ADD2 119 adducin 2 (beta) actin cytoskeleton organization Biological process 3693401 ELAC1 55520 elaC ribonuclease Z 1 nucleus Cellular component 21593607 GABRR3 200959 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) ion transmembrane transport Biological process - CCL3 6348 chemokine (C-C motif) ligand 3 eosinophil chemotaxis Biological process 10072545 XRN1 54464 5'-3' exoribonuclease 1 membrane Cellular component 19946888 RAC3 5881 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) regulation of small GTPase mediated signal transduction Biological process - RAD9A 5883 RAD9 homolog A (S. pombe) cellular response to DNA damage stimulus Biological process 9872989 SMPD1 6609 sphingomyelin phosphodiesterase 1, acid lysosomal glycosphingolipid metabolic process Biological process - MITF 4286 microphthalmia-associated transcription factor regulation of osteoclast differentiation Biological process - VTI1A 143187 vesicle transport through interaction with t-SNAREs 1A Golgi ribbon formation Biological process 23677696 HSFY2 159119 heat shock transcription factor, Y linked 2 protein binding Molecular function 25416956 PAPSS2 9060 3'-phosphoadenosine 5'-phosphosulfate synthase 2 bone development Biological process - CNTN1 1272 contactin 1 Notch signaling pathway Biological process - RALB 5899 v-ral simian leukemia viral oncogene homolog B extracellular exosome Cellular component 23376485 LMO2 4005 LIM domain only 2 (rhombotin-like 1) protein binding Molecular function 16189514 NFE2L2 4780 nuclear factor, erythroid 2-like 2 RNA polymerase II activating transcription factor binding Molecular function 23043106 PLK2 10769 polo-like kinase 2 negative regulation of apoptotic process Biological process - ACTR1A 10121 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) dynactin complex Cellular component - PRPF6 24148 pre-mRNA processing factor 6 spliceosomal tri-snRNP complex assembly Biological process 15257298 ERMP1 79956 endoplasmic reticulum metallopeptidase 1 endoplasmic reticulum membrane Cellular component - LIN7B 64130 lin-7 homolog B (C. elegans) plasma membrane Cellular component - ATP8B3 148229 ATPase, aminophospholipid transporter, class I, type 8B, member 3 magnesium ion binding Molecular function - PRPF8 10594 pre-mRNA processing factor 8 RNA splicing Biological process 9774689 RIMS1 22999 regulating synaptic membrane exocytosis 1 presynaptic membrane Cellular component 11438518 STUB1 10273 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase regulation of glucocorticoid metabolic process Biological process 11146632 AGRN 375790 agrin calcium ion binding Molecular function - KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog detection of mechanical stimulus involved in sensory perception of sound Biological process - ARFGAP2 84364 ADP-ribosylation factor GTPase activating protein 2 nucleolus Cellular component - FOXA2 3170 forkhead box A2 primitive streak formation Biological process - RAPGEF3 10411 Rap guanine nucleotide exchange factor (GEF) 3 positive regulation of syncytium formation by plasma membrane fusion Biological process 23867755 CTNNA2 1496 catenin (cadherin-associated protein), alpha 2 muscle cell differentiation Biological process - MTCH2 23788 mitochondrial carrier 2 regulation of mitochondrial membrane permeability involved in apoptotic process Biological process - C11orf1 64776 chromosome 11 open reading frame 1 nucleoplasm Cellular component - CCR7 1236 chemokine (C-C motif) receptor 7 intracellular Cellular component 21051556 FANCD2 2177 Fanconi anemia, complementation group D2 Golgi apparatus Cellular component - H2AFV 94239 H2A histone family, member V nucleus Cellular component 16457589 PTPMT1 114971 protein tyrosine phosphatase, mitochondrial 1 protein tyrosine phosphatase activity Molecular function - CAV1 857 caveolin 1, caveolae protein, 22kDa regulation of heart rate by cardiac conduction Biological process - PCM1 5108 pericentriolar material 1 protein complex Cellular component 24421332 FOXG1 2290 forkhead box G1 protein binding Molecular function 12657635 PDPN 10630 podoplanin lung alveolus development Biological process - ATG4D 84971 autophagy related 4D, cysteine peptidase C-terminal protein lipidation Biological process - NR4A1 3164 nuclear receptor subfamily 4, group A, member 1 positive regulation of transcription from RNA polymerase II promoter Biological process 22427340 TNF 7124 tumor necrosis factor positive regulation of interferon-gamma production Biological process - NUP85 79902 nucleoporin 85kDa cytokine-mediated signaling pathway Biological process - LENG1 79165 leukocyte receptor cluster (LRC) member 1 protein binding Molecular function 25416956 PSMD10 5716 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 nucleus Cellular component 18040287 PRC1 9055 protein regulator of cytokinesis 1 identical protein binding Molecular function 20691902 TICAM1 148022 toll-like receptor adaptor molecule 1 defense response to virus Biological process - HSF2 3298 heat shock transcription factor 2 spermatogenesis Biological process - COPB1 1315 coatomer protein complex, subunit beta 1 cytoplasm Cellular component - CRTAC1 55118 cartilage acidic protein 1 olfactory bulb development Biological process - CRH 1392 corticotropin releasing hormone negative regulation of luteinizing hormone secretion Biological process - NPLOC4 55666 nuclear protein localization 4 homolog (S. cerevisiae) retrograde protein transport, ER to cytosol Biological process 25660456 BDP1 55814 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB regulation of transcription from RNA polymerase III promoter Biological process - PAPLN 89932 papilin, proteoglycan-like sulfated glycoprotein serine-type endopeptidase inhibitor activity Molecular function - FGFR2 2263 fibroblast growth factor receptor 2 angiogenesis Biological process - DUSP28 285193 dual specificity phosphatase 28 JNK cascade Biological process - AACS 65985 acetoacetyl-CoA synthetase white fat cell differentiation Biological process - OGG1 4968 8-oxoguanine DNA glycosylase response to drug Biological process - SLC4A5 57835 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 cerebrospinal fluid secretion Biological process - SRP68 6730 signal recognition particle 68kDa signal recognition particle binding Molecular function 17254600 PCK2 5106 phosphoenolpyruvate carboxykinase 2 (mitochondrial) response to glucocorticoid Biological process - PRMT8 56341 protein arginine methyltransferase 8 regulation of transcription, DNA-templated Biological process - ADCY3 109 adenylate cyclase 3 metal ion binding Molecular function - CASC5 57082 cancer susceptibility candidate 5 cytosol Cellular component - HLA-DQA1 3117 major histocompatibility complex, class II, DQ alpha 1 MHC class II receptor activity Molecular function 2300572 GYPA 2993 glycophorin A (MNS blood group) external side of plasma membrane Cellular component - NR1D2 9975 nuclear receptor subfamily 1, group D, member 2 intracellular receptor signaling pathway Biological process 7997240 MOAP1 64112 modulator of apoptosis 1 positive regulation of apoptotic process Biological process 15949439 ARRB2 409 arrestin, beta 2 positive regulation of synaptic transmission, dopaminergic Biological process - ASNA1 439 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) transport Biological process 9736449 TGFB3 7043 transforming growth factor, beta 3 lung alveolus development Biological process - GCNT1 2650 glucosaminyl (N-acetyl) transferase 1, core 2 protein O-linked glycosylation Biological process - TPM1 7168 tropomyosin 1 (alpha) ventricular cardiac muscle tissue morphogenesis Biological process 11136687 DHX36 170506 DEAH (Asp-Glu-Ala-His) box polypeptide 36 response to exogenous dsRNA Biological process - DUOXA2 405753 dual oxidase maturation factor 2 endoplasmic reticulum membrane Cellular component - AKR1B1 231 aldo-keto reductase family 1, member B1 (aldose reductase) oxidation-reduction process Biological process - CKLF 51192 chemokine-like factor secretion by cell Biological process 11415443 PTK2B 2185 protein tyrosine kinase 2 beta cellular defense response Biological process - TP53TG5 27296 TP53 target 5 nucleus Cellular component 21630459 NPM1 4869 nucleophosmin (nucleolar phosphoprotein B23, numatrin) nucleus Cellular component - TNKS 8658 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase protein polyubiquitination Biological process 19759537 PIGA 5277 phosphatidylinositol glycan anchor biosynthesis, class A membrane Cellular component 19946888 SLC26A1 10861 solute carrier family 26 (anion exchanger), member 1 anion:anion antiporter activity Molecular function - APP 351 amyloid beta (A4) precursor protein protein binding Molecular function 10049767 HJURP 55355 Holliday junction recognition protein nucleoplasm Cellular component - HAUS1 115106 HAUS augmin-like complex, subunit 1 HAUS complex Cellular component 19369198 MYRIP 25924 myosin VIIA and Rab interacting protein zinc ion binding Molecular function 11964381 DSTYK 25778 dual serine/threonine and tyrosine protein kinase protein tyrosine kinase activity Molecular function - RNF216 54476 ring finger protein 216 proteasome-mediated ubiquitin-dependent protein catabolic process Biological process 19893624 EDN1 1906 endothelin 1 negative regulation of hormone secretion Biological process - SMARCAL1 50485 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 ATP binding Molecular function - ERBB2 2064 erb-b2 receptor tyrosine kinase 2 positive regulation of transcription from RNA polymerase III promoter Biological process 19372587 HCN4 10021 hyperpolarization activated cyclic nucleotide gated potassium channel 4 SA node cell action potential Biological process 12750403 PPP2R5B 5526 protein phosphatase 2, regulatory subunit B', beta endoplasmic reticulum unfolded protein response Biological process - MYB 4602 v-myb avian myeloblastosis viral oncogene homolog B cell differentiation Biological process - SYNE2 23224 spectrin repeat containing, nuclear envelope 2 nuclear lumen Cellular component 15671068 LTF 4057 lactotransferrin iron ion binding Molecular function 12037568 HLA-A 3105 major histocompatibility complex, class I, A detection of bacterium Biological process 22321387 COX17 10063 COX17 cytochrome c oxidase copper chaperone heart development Biological process - MTPAP 55149 mitochondrial poly(A) polymerase mitochondrion Cellular component - TGFB2 7042 transforming growth factor, beta 2 cartilage condensation Biological process - SDC2 6383 syndecan 2 response to hypoxia Biological process - AZI2 64343 5-azacytidine induced 2 interleukin-6 production Biological process - GRHL3 57822 grainyhead-like 3 (Drosophila) cochlea morphogenesis Biological process - ODF1 4956 outer dense fiber of sperm tails 1 spermatogenesis Biological process - TFAM 7019 transcription factor A, mitochondrial mitochondrial matrix Cellular component - ABAT 18 4-aminobutyrate aminotransferase extracellular exosome Cellular component 23376485 FGF7 2252 fibroblast growth factor 7 protein binding Molecular function 1309608 PSMG1 8624 proteasome (prosome, macropain) assembly chaperone 1 protein binding Molecular function 16251969 GNG7 2788 guanine nucleotide binding protein (G protein), gamma 7 G-protein coupled receptor signaling pathway Biological process - E4F1 1877 E4F transcription factor 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function - RAB10 10890 RAB10, member RAS oncogene family endosomal transport Biological process 16641372 GGT1 2678 gamma-glutamyltransferase 1 gamma-glutamyltransferase activity Molecular function 18357469 SRSF10 10772 serine/arginine-rich splicing factor 10 cytoplasm Cellular component 11684676 CIDEB 27141 cell death-inducing DFFA-like effector b positive regulation of release of cytochrome c from mitochondria Biological process 12595532 NGB 58157 neuroglobin protein binding Molecular function 25416956 HIST1H2BN 8341 histone cluster 1, H2bn DNA binding Molecular function 9439656 WNT5A 7474 wingless-type MMTV integration site family, member 5A positive regulation of thymocyte apoptotic process Biological process - EIF4EBP1 1978 eukaryotic translation initiation factor 4E binding protein 1 negative regulation of translational initiation Biological process 22578813 GCN1L1 10985 GCN1 general control of amino-acid synthesis 1-like 1 (yeast) membrane Cellular component 19946888 JAGN1 84522 jagunal homolog 1 (Drosophila) protein binding Molecular function 25416956 OLIG2 10215 oligodendrocyte lineage transcription factor 2 myelination Biological process - SRPX2 27286 sushi-repeat containing protein, X-linked 2 cell motility Biological process 19065654 HAPLN2 60484 hyaluronan and proteoglycan link protein 2 extracellular matrix assembly Biological process - DMD 1756 dystrophin positive regulation of sodium ion transmembrane transporter activity Biological process 21677768 SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) oxidation-reduction process Biological process 21320589 EGFR 1956 epidermal growth factor receptor apical plasma membrane Cellular component - TMEM248 55069 transmembrane protein 248 protein binding Molecular function 25416956 GLT6D1 360203 glycosyltransferase 6 domain containing 1 transferase activity, transferring hexosyl groups Molecular function - ZNF774 342132 zinc finger protein 774 protein binding Molecular function 25416956 UQCRC2 7385 ubiquinol-cytochrome c reductase core protein II mitochondrial respiratory chain complex III Cellular component - DNAH10 196385 dynein, axonemal, heavy chain 10 metabolic process Biological process - SHANK2 22941 SH3 and multiple ankyrin repeat domains 2 memory Biological process - SESN1 27244 sestrin 1 negative regulation of cell proliferation Biological process 9926927 CLASP2 23122 cytoplasmic linker associated protein 2 membrane Cellular component 19946888 USP3 9960 ubiquitin specific peptidase 3 mitotic cell cycle Biological process 17980597 EGFR 1956 epidermal growth factor receptor regulation of nitric-oxide synthase activity Biological process 12828935 NKD1 85407 naked cuticle homolog 1 (Drosophila) protein binding Molecular function 15687260 TAF7 6879 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa DNA-templated transcription, initiation Biological process 9603525 THBS1 7057 thrombospondin 1 immune response Biological process 18674744 RRM2 6241 ribonucleotide reductase M2 nucleobase-containing small molecule interconversion Biological process - RFC4 5984 replication factor C (activator 1) 4, 37kDa telomere maintenance Biological process - TTN 7273 titin cardiac muscle fiber development Biological process 9817758 HMG20A 10363 high mobility group 20A protein heterodimerization activity Molecular function - ACVRL1 94 activin A receptor type II-like 1 positive regulation of angiogenesis Biological process - CCNB2 9133 cyclin B2 protein binding Molecular function 15232106 CASP8 841 caspase 8, apoptosis-related cysteine peptidase cellular response to mechanical stimulus Biological process 19593445 CCR5 1234 chemokine (C-C motif) receptor 5 (gene/pseudogene) cell surface receptor signaling pathway Biological process 8639485 TWIST1 7291 twist family bHLH transcription factor 1 embryonic camera-type eye formation Biological process 17070479 VEGFB 7423 vascular endothelial growth factor B positive regulation of peptidyl-tyrosine phosphorylation Biological process 11122379 GLS 2744 glutaminase synaptic transmission Biological process - RAPGEF1 2889 Rap guanine nucleotide exchange factor (GEF) 1 negative regulation of protein kinase B signaling Biological process - PRKAB2 5565 protein kinase, AMP-activated, beta 2 non-catalytic subunit protein binding Molecular function 16306228 SMARCD1 6602 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 chromatin-mediated maintenance of transcription Biological process 12917342 NLRP3 114548 NLR family, pyrin domain containing 3 defense response to virus Biological process - CPT2 1376 carnitine palmitoyltransferase 2 nucleolus Cellular component - IFT81 28981 intraflagellar transport 81 sperm principal piece Cellular component - PPP4R2 151987 protein phosphatase 4, regulatory subunit 2 regulation of catalytic activity Biological process 20154705 DUSP15 128853 dual specificity phosphatase 15 transforming growth factor beta receptor signaling pathway Biological process - OSGIN1 29948 oxidative stress induced growth inhibitor 1 negative regulation of cell growth Biological process 11459809 H2AFY 9555 H2A histone family, member Y positive regulation of gene expression, epigenetic Biological process 25526730 NPTN 27020 neuroplastin cell adhesion molecule binding Molecular function - CNBP 7555 CCHC-type zinc finger, nucleic acid binding protein protein binding Molecular function 24726729 CDC5L 988 cell division cycle 5-like mRNA splicing, via spliceosome Biological process - ME2 4200 malic enzyme 2, NAD(+)-dependent, mitochondrial intracellular membrane-bounded organelle Cellular component - TRIM36 55521 tripartite motif containing 36 ligase activity Molecular function - ZNF292 23036 zinc finger protein 292 transcription, DNA-templated Biological process - COPS5 10987 COP9 signalosome subunit 5 transcription from RNA polymerase II promoter Biological process 8837781 RPL14 9045 ribosomal protein L14 cytoplasm Cellular component - NPFF 8620 neuropeptide FF-amide peptide precursor neuropeptide signaling pathway Biological process - LIF 3976 leukemia inhibitory factor regulation of metanephric nephron tubule epithelial cell differentiation Biological process 20624457 CMC1 152100 C-x(9)-C motif containing 1 mitochondrion Cellular component - RAP2A 5911 RAP2A, member of RAS oncogene family actin cytoskeleton reorganization Biological process 15342639 BRE 9577 brain and reproductive organ-expressed (TNFRSF1A modulator) peroxisome targeting sequence binding Molecular function 11676476 SPESP1 246777 sperm equatorial segment protein 1 fusion of sperm to egg plasma membrane Biological process - SPAST 6683 spastin cytoplasm Cellular component 16026783 TRIM31 11074 tripartite motif containing 31 protein binding Molecular function 16189514 CLDN14 23562 claudin 14 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules Biological process - GTF3C5 9328 general transcription factor IIIC, polypeptide 5, 63kDa transcription, DNA-templated Biological process 17409385 GATA6 2627 GATA binding protein 6 positive regulation of angiogenesis Biological process 21127043 DCX 1641 doublecortin dendrite morphogenesis Biological process - INSR 3643 insulin receptor epidermis development Biological process - ZNF645 158506 zinc finger protein 645 regulation of cell adhesion Biological process - MST1 4485 macrophage stimulating 1 proteolysis Biological process - MAP3K4 4216 mitogen-activated protein kinase kinase kinase 4 positive regulation of p38MAPK cascade Biological process 9305639 GFI1 2672 growth factor independent 1 transcription repressor negative regulation of cell fate specification Biological process - KATNA1 11104 katanin p60 (ATPase containing) subunit A 1 cell division Biological process - GMNN 51053 geminin, DNA replication inhibitor organ morphogenesis Biological process - KIF14 9928 kinesin family member 14 microtubule Cellular component 23209302 DCXR 51181 dicarbonyl/L-xylulose reductase extracellular exosome Cellular component 19056867 CCT7 10574 chaperonin containing TCP1, subunit 7 (eta) cytosol Cellular component - NANOG 79923 Nanog homeobox regulation of gene expression Biological process 18388306 ZKSCAN1 7586 zinc finger with KRAB and SCAN domains 1 sequence-specific DNA binding transcription factor activity Molecular function 7557990 VWF 7450 von Willebrand factor hemostasis Biological process 10887119 HSF4 3299 heat shock transcription factor 4 negative regulation of transcription from RNA polymerase II promoter Biological process - ABCC8 6833 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 ATPase activity, coupled to transmembrane movement of substances Molecular function - PTMS 5763 parathymosin DNA replication Biological process 10854063 KCNK3 3777 potassium channel, two pore domain subfamily K, member 3 protein C-terminus binding Molecular function - HIST1H4J 8363 histone cluster 1, H4j DNA binding Molecular function 3035717 PAX6 5080 paired box 6 interkinetic nuclear migration Biological process - PITPNM2 57605 phosphatidylinositol transfer protein, membrane-associated 2 endomembrane system Cellular component - ELL 8178 elongation factor RNA polymerase II protein binding Molecular function 19389623 BRD4 23476 bromodomain containing 4 regulation of phosphorylation of RNA polymerase II C-terminal domain Biological process 23086925 HIST1H4H 8365 histone cluster 1, H4h protein complex Cellular component 14718166 GRASP 160622 GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein cell junction Cellular component - TUBGCP2 10844 tubulin, gamma complex associated protein 2 cytoplasmic microtubule Cellular component 9566967 GHRH 2691 growth hormone releasing hormone positive regulation of circadian sleep/wake cycle, REM sleep Biological process 18329818 LRRFIP1 9208 leucine rich repeat (in FLII) interacting protein 1 biological_process Biological process - RIPK1 8737 receptor (TNFRSF)-interacting serine-threonine kinase 1 activation of cysteine-type endopeptidase activity involved in apoptotic process Biological process - ADCY7 113 adenylate cyclase 7 adenylate cyclase activity Molecular function 11113152 PRSS16 10279 protease, serine, 16 (thymus) lysosome Cellular component 10527559 FFAR3 2865 free fatty acid receptor 3 inflammatory response Biological process - PROC 5624 protein C (inactivator of coagulation factors Va and VIIIa) negative regulation of apoptotic process Biological process 12563316 LRP1 4035 low density lipoprotein receptor-related protein 1 nucleolus Cellular component - PBX2 5089 pre-B-cell leukemia homeobox 2 transcription factor complex Cellular component - TAF13 6884 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa transcription initiation from RNA polymerase II promoter Biological process - SKI 6497 SKI proto-oncogene protein domain specific binding Molecular function 11441023 GART 2618 phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase methyltransferase activity Molecular function - ZNF833P 401898 zinc finger protein 833, pseudogene metal ion binding Molecular function - COL4A3 1285 collagen, type IV, alpha 3 (Goodpasture antigen) endothelial cell apoptotic process Biological process 10766752 PRMT7 54496 protein arginine methyltransferase 7 protein-arginine omega-N asymmetric methyltransferase activity Molecular function - BPGM 669 2,3-bisphosphoglycerate mutase bisphosphoglycerate 2-phosphatase activity Molecular function - HIST3H2BB 128312 histone cluster 3, H2bb molecular_function Molecular function - RPS2 6187 ribosomal protein S2 fibroblast growth factor binding Molecular function 16263090 UCN2 90226 urocortin 2 extracellular region Cellular component 11329063 ZFP36 7538 ZFP36 ring finger protein single-stranded RNA binding Molecular function 9703499 PRAMEF7 441871 PRAME family member 7 negative regulation of retinoic acid receptor signaling pathway Biological process - OR2A4 79541 olfactory receptor, family 2, subfamily A, member 4 olfactory receptor activity Molecular function - THOC1 9984 THO complex 1 mRNA export from nucleus Biological process 22144908 SERPINE2 5270 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 negative regulation of endopeptidase activity Biological process - RPL5 6125 ribosomal protein L5 viral life cycle Biological process - FKBP8 23770 FK506 binding protein 8, 38kDa metal ion binding Molecular function - NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 cell surface Cellular component - FIZ1 84922 FLT3-interacting zinc finger 1 regulation of transcription, DNA-templated Biological process - ZNF226 7769 zinc finger protein 226 regulation of transcription, DNA-templated Biological process - PTPRC 5788 protein tyrosine phosphatase, receptor type, C transmembrane receptor protein tyrosine phosphatase activity Molecular function 2845400 TNF 7124 tumor necrosis factor activation of MAPK activity Biological process 10748004 PRDM13 59336 PR domain containing 13 negative regulation of transcription from RNA polymerase II promoter Biological process - EPHX2 2053 epoxide hydrolase 2, cytoplasmic magnesium ion binding Molecular function 12574510 MGST1 4257 microsomal glutathione S-transferase 1 protein homotrimerization Biological process - CH25H 9023 cholesterol 25-hydroxylase oxidation-reduction process Biological process - GUCY2F 2986 guanylate cyclase 2F, retinal receptor guanylyl cyclase signaling pathway Biological process 7777544 KIAA1919 91749 KIAA1919 integral component of membrane Cellular component - RBM33 155435 RNA binding motif protein 33 poly(A) RNA binding Molecular function 22658674 ZC3H12A 80149 zinc finger CCCH-type containing 12A positive regulation of autophagy Biological process 22739135 FLOT1 10211 flotillin 1 response to endoplasmic reticulum stress Biological process 25204797 PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide protein kinase binding Molecular function 16479011 UBE2L3 7332 ubiquitin-conjugating enzyme E2L 3 protein binding Molecular function 10888878 TNXB 7148 tenascin XB cell adhesion Biological process - PRUNE2 158471 prune homolog 2 (Drosophila) metal ion binding Molecular function - CYR61 3491 cysteine-rich, angiogenic inducer, 61 atrioventricular valve morphogenesis Biological process - MYH10 4628 myosin, heavy chain 10, non-muscle stress fiber Cellular component 15774463 CKAP2L 150468 cytoskeleton associated protein 2-like cytoplasm Cellular component - ELOVL7 79993 ELOVL fatty acid elongase 7 endoplasmic reticulum membrane Cellular component - CDC23 8697 cell division cycle 23 regulation of exit from mitosis Biological process 9790767 TEC 7006 tec protein tyrosine kinase adaptive immune response Biological process - CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 response to immobilization stress Biological process - NAMPT 10135 nicotinamide phosphoribosyltransferase positive regulation of transcription from RNA polymerase II promoter Biological process 23001182 NOXRED1 122945 NADP-dependent oxidoreductase domain containing 1 proline biosynthetic process Biological process - TBC1D12 23232 TBC1 domain family, member 12 GTPase activator activity Molecular function - DUSP5 1847 dual specificity phosphatase 5 MAP kinase tyrosine/serine/threonine phosphatase activity Molecular function - SLC9A3R1 9368 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 regulation of sodium:proton antiporter activity Biological process 9560162 MED1 5469 mediator complex subunit 1 sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function - C10orf99 387695 chromosome 10 open reading frame 99 negative regulation of cell division Biological process 25351403 PSG6 5675 pregnancy specific beta-1-glycoprotein 6 extracellular region Cellular component 2271648 PSEN1 5663 presenilin 1 endoplasmic reticulum Cellular component 15274632 NR5A1 2516 nuclear receptor subfamily 5, group A, member 1 transcription coactivator activity Molecular function 8205615 SPRY2 10253 sprouty homolog 2 (Drosophila) protein kinase binding Molecular function 20736167 IL2RA 3559 interleukin 2 receptor, alpha interleukin-2 receptor activity Molecular function - BUB1 699 BUB1 mitotic checkpoint serine/threonine kinase protein binding Molecular function 10198256 HLA-DMA 3108 major histocompatibility complex, class II, DM alpha MHC class II protein complex binding Molecular function 22733780 BTC 685 betacellulin intracellular Cellular component - PGF 5228 placental growth factor cell differentiation Biological process - CHCHD3 54927 coiled-coil-helix-coiled-coil-helix domain containing 3 extracellular exosome Cellular component 19056867 SF3B5 83443 splicing factor 3b, subunit 5, 10kDa gene expression Biological process - MSX2 4488 msh homeobox 2 cellular response to estradiol stimulus Biological process - DDX49 54555 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 ATP-dependent RNA helicase activity Molecular function - CCNF 899 cyclin F re-entry into mitotic cell cycle Biological process - CBLN1 869 cerebellin 1 precursor heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules Biological process - ADAMTSL5 339366 ADAMTS-like 5 heparin binding Molecular function 23010571 GMFB 2764 glia maturation factor, beta learning Biological process - HDAC4 9759 histone deacetylase 4 cytoplasm Cellular component - FASLG 356 Fas ligand (TNF superfamily, member 6) integral component of plasma membrane Cellular component 7826947 CDH19 28513 cadherin 19, type 2 plasma membrane Cellular component - CHRDL1 91851 chordin-like 1 compound eye development Biological process 22284829 VAT1 10493 vesicle amine transport 1 oxidation-reduction process Biological process - CLCN3 1182 chloride channel, voltage-sensitive 3 volume-sensitive chloride channel activity Molecular function 12183454 PSMA5 5686 proteasome (prosome, macropain) subunit, alpha type, 5 regulation of apoptotic process Biological process - STK24 8428 serine/threonine kinase 24 cytosol Cellular component - RELL1 768211 RELT-like 1 integral component of membrane Cellular component - AGO1 26523 argonaute RISC catalytic component 1 protein binding Molecular function 12526743 XPA 7507 xeroderma pigmentosum, complementation group A metal ion binding Molecular function - GPR171 29909 G protein-coupled receptor 171 integral component of membrane Cellular component 9370294 NELFE 7936 negative elongation factor complex member E negative regulation of mRNA polyadenylation Biological process 19575011 TRNT1 51095 tRNA nucleotidyl transferase, CCA-adding, 1 mitochondrion Cellular component - CHRNA9 55584 cholinergic receptor, nicotinic, alpha 9 (neuronal) cytosol Cellular component 18420419 PEX3 8504 peroxisomal biogenesis factor 3 protein dimerization activity Molecular function 19715730 BCAM 4059 basal cell adhesion molecule (Lutheran blood group) laminin receptor activity Molecular function 16236823 SCAMP3 10067 secretory carrier membrane protein 3 ubiquitin protein ligase binding Molecular function 23418353 SLC39A2 29986 solute carrier family 39 (zinc transporter), member 2 zinc II ion transport Biological process 10681536 FLVCR1 28982 feline leukemia virus subgroup C cellular receptor 1 in utero embryonic development Biological process - MAP1LC3C 440738 microtubule-associated protein 1 light chain 3 gamma autophagosome Cellular component 12740394 CELF2 10659 CUGBP, Elav-like family member 2 nucleotide binding Molecular function - IZUMO1 284359 izumo sperm-egg fusion 1 protein homodimerization activity Molecular function - NR2E3 10002 nuclear receptor subfamily 2, group E, member 3 transcription from RNA polymerase II promoter Biological process 10220376 KIR2DS4 3809 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4 innate immune response Biological process - HNF1A 6927 HNF1 homeobox A protein homodimerization activity Molecular function 1677179 FST 10468 follistatin keratinocyte proliferation Biological process - MAN1B1 11253 mannosidase, alpha, class 1B, member 1 cellular protein metabolic process Biological process - SNAI2 6591 snail family zinc finger 2 nucleus Cellular component 10866665 TGM3 7053 transglutaminase 3 extracellular exosome Cellular component 19199708 CCL2 6347 chemokine (C-C motif) ligand 2 extracellular space Cellular component - GIPR 2696 gastric inhibitory polypeptide receptor endocrine pancreas development Biological process - THPO 7066 thrombopoietin positive regulation of protein kinase B signaling Biological process - ELOVL3 83401 ELOVL fatty acid elongase 3 long-chain fatty-acyl-CoA biosynthetic process Biological process - CAMK1D 57118 calcium/calmodulin-dependent protein kinase ID calmodulin-dependent protein kinase activity Molecular function - CRISPLD1 83690 cysteine-rich secretory protein LCCL domain containing 1 molecular_function Molecular function - ADCY4 196883 adenylate cyclase 4 epidermal growth factor receptor signaling pathway Biological process - HAS1 3036 hyaluronan synthase 1 extracellular matrix assembly Biological process - CEACAM7 1087 carcinoembryonic antigen-related cell adhesion molecule 7 plasma membrane Cellular component - ENSA 2029 endosulfine alpha response to glucose Biological process - CRABP1 1381 cellular retinoic acid binding protein 1 signal transduction Biological process 1309505 CTNNA2 1496 catenin (cadherin-associated protein), alpha 2 structural constituent of cytoskeleton Molecular function 8432524 FOXN4 121643 forkhead box N4 sequence-specific DNA binding transcription factor activity Molecular function - WNT11 7481 wingless-type MMTV integration site family, member 11 frizzled binding Molecular function - SAP30BP 29115 SAP30 binding protein nucleoplasm Cellular component - APBB2 323 amyloid beta (A4) precursor protein-binding, family B, member 2 neuron migration Biological process - ZNF311 282890 zinc finger protein 311 sequence-specific DNA binding transcription factor activity Molecular function - TRPC3 7222 transient receptor potential cation channel, subfamily C, member 3 positive regulation of cardiac muscle hypertrophy in response to stress Biological process 19287093 ICE2 79664 interactor of little elongation complex ELL subunit 2 transcription elongation factor complex Cellular component 22195968 MKRN1 23608 makorin ring finger protein 1 poly(A) RNA binding Molecular function 22658674 DCLK2 166614 doublecortin-like kinase 2 ATP binding Molecular function - TYR 7299 tyrosinase integral component of membrane Cellular component - STAB2 55576 stabilin 2 carbohydrate metabolic process Biological process - NOTO 344022 notochord homeobox dorsal/ventral pattern formation Biological process - FAM110C 642273 family with sequence similarity 110, member C alpha-tubulin binding Molecular function 19698782 DCUN1D5 84259 DCN1, defective in cullin neddylation 1, domain containing 5 biological_process Biological process - BTRC 8945 beta-transducin repeat containing E3 ubiquitin protein ligase branching involved in mammary gland duct morphogenesis Biological process - CLTC 1213 clathrin, heavy chain (Hc) clathrin coat Cellular component 1765375 PM20D2 135293 peptidase M20 domain containing 2 nucleoplasm Cellular component - ZAK 51776 sterile alpha motif and leucine zipper containing kinase AZK nucleus Cellular component - JADE3 9767 jade family PHD finger 3 histone acetyltransferase complex Cellular component 16387653 PSMC1 5700 proteasome (prosome, macropain) 26S subunit, ATPase, 1 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Biological process - KRT18 3875 keratin 18, type I cell periphery Cellular component - ANAPC10 10393 anaphase promoting complex subunit 10 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Biological process - EIF1AX 1964 eukaryotic translation initiation factor 1A, X-linked protein binding Molecular function 21139563 PARVG 64098 parvin, gamma focal adhesion Cellular component - TRAPPC1 58485 trafficking protein particle complex 1 TRAPP complex Cellular component - BAIAP3 8938 BAI1-associated protein 3 G-protein coupled receptor signaling pathway Biological process 9790924 BIRC8 112401 baculoviral IAP repeat containing 8 inhibition of cysteine-type endopeptidase activity involved in apoptotic process Biological process - PRKAR2A 5576 protein kinase, cAMP-dependent, regulatory, type II, alpha cAMP binding Molecular function - G6PD 2539 glucose-6-phosphate dehydrogenase erythrocyte maturation Biological process 5643703 FXYD5 53827 FXYD domain containing ion transport regulator 5 negative regulation of calcium-dependent cell-cell adhesion Biological process 11756660 KLK8 11202 kallikrein-related peptidase 8 memory Biological process - PTMS 5763 parathymosin immune system process Biological process - CABP4 57010 calcium binding protein 4 signal transduction Biological process 10625670 STRA6 64220 stimulated by retinoic acid 6 artery morphogenesis Biological process 17273977 PDE8B 8622 phosphodiesterase 8B 3',5'-cyclic-nucleotide phosphodiesterase activity Molecular function 9784418 PIANP 196500 PILR alpha associated neural protein integral component of membrane Cellular component - GLI1 2735 GLI family zinc finger 1 ventral midline development Biological process - COX11 1353 COX11 cytochrome c oxidase copper chaperone respiratory gaseous exchange Biological process 9878253 PEX5 5830 peroxisomal biogenesis factor 5 protein import into peroxisome matrix, docking Biological process 21976670 HADH 3033 hydroxyacyl-CoA dehydrogenase cellular lipid metabolic process Biological process - LRRTM2 26045 leucine rich repeat transmembrane neuronal 2 postsynaptic membrane Cellular component - COL10A1 1300 collagen, type X, alpha 1 cartilage development Biological process - TNFSF18 8995 tumor necrosis factor (ligand) superfamily, member 18 T cell proliferation involved in immune response Biological process - FGFR2 2263 fibroblast growth factor receptor 2 epidermis morphogenesis Biological process - MRAP 56246 melanocortin 2 receptor accessory protein positive regulation of cAMP biosynthetic process Biological process 19329486 ZNF337 26152 zinc finger protein 337 regulation of transcription, DNA-templated Biological process - PFDN2 5202 prefoldin subunit 2 extracellular exosome Cellular component 23376485 SLC9A9 285195 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 late endosome membrane Cellular component - GALR1 2587 galanin receptor 1 galanin receptor activity Molecular function 24517231 GOT1 2805 glutamic-oxaloacetic transaminase 1, soluble L-cysteine:2-oxoglutarate aminotransferase activity Molecular function - DDX23 9416 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 extracellular exosome Cellular component 19199708 LONRF1 91694 LON peptidase N-terminal domain and ring finger 1 protein binding Molecular function 19549727 MAP6D1 79929 MAP6 domain containing 1 microtubule binding Molecular function - ARHGAP11A 9824 Rho GTPase activating protein 11A positive regulation of GTPase activity Biological process - RBPJL 11317 recombination signal binding protein for immunoglobulin kappa J region-like signal transduction Biological process 9929984 IGHM 3507 immunoglobulin heavy constant mu adaptive immune response Biological process 21786026 CLK3 1198 CDC-like kinase 3 protein phosphorylation Biological process 9637771 IPO8 10526 importin 8 gene expression Biological process - ATG9A 79065 autophagy related 9A late endosome Cellular component 22456507 ATP5C1 509 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 mitochondrial ATP synthesis coupled proton transport Biological process - KDM4C 23081 lysine (K)-specific demethylase 4C small GTPase mediated signal transduction Biological process - MLYCD 23417 malonyl-CoA decarboxylase mitochondrion Cellular component 10417274 XRCC1 7515 X-ray repair complementing defective repair in Chinese hamster cells 1 response to organic substance Biological process - ADIPOQ 9370 adiponectin, C1Q and collagen domain containing protein heterotrimerization Biological process - TCEB2 6923 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) extracellular exosome Cellular component 23376485 TMEM64 169200 transmembrane protein 64 positive regulation of bone resorption Biological process - UBE2G2 7327 ubiquitin-conjugating enzyme E2G 2 cytosol Cellular component 16780588 DAO 1610 D-amino-acid oxidase cellular nitrogen compound metabolic process Biological process - SOD1 6647 superoxide dismutase 1, soluble copper ion binding Molecular function 17008312 EBP 10682 emopamil binding protein (sterol isomerase) cholesterol metabolic process Biological process 10391219 G6PC3 92579 glucose 6 phosphatase, catalytic, 3 integral component of endoplasmic reticulum membrane Cellular component - WDR3 10885 WD repeat domain 3 small-subunit processome Cellular component - LAMP2 3920 lysosomal-associated membrane protein 2 phagocytic vesicle membrane Cellular component - SLC16A13 201232 solute carrier family 16, member 13 integral component of membrane Cellular component - HSP90B1 7184 heat shock protein 90kDa beta (Grp94), member 1 response to hypoxia Biological process 15620698 UBIAD1 29914 UbiA prenyltransferase domain containing 1 cytoplasm Cellular component 11314041 ZDHHC8 29801 zinc finger, DHHC-type containing 8 cytoplasmic vesicle membrane Cellular component - HEY1 23462 hes-related family bHLH transcription factor with YRPW motif 1 umbilical cord morphogenesis Biological process - SLC9A9 285195 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 protein binding Molecular function 24705354 ARFGEF1 10565 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) nucleoplasm Cellular component - AVPR2 554 arginine vasopressin receptor 2 hemostasis Biological process 10880054 STAB2 55576 stabilin 2 low-density lipoprotein receptor activity Molecular function 12077138 TMEM231 79583 transmembrane protein 231 cilium assembly Biological process - NFATC4 4776 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 transcription coactivator activity Molecular function 7749981 PFN3 345456 profilin 3 cytoskeleton Cellular component - SEMA4D 10507 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D transmembrane signaling receptor activity Molecular function 20877282 SLC1A7 6512 solute carrier family 1 (glutamate transporter), member 7 L-glutamate transmembrane transporter activity Molecular function 9108121 CCDC22 28952 coiled-coil domain containing 22 cullin family protein binding Molecular function 23563313 CRTC1 23373 CREB regulated transcription coactivator 1 positive regulation of transcription from RNA polymerase II promoter Biological process 14536081 ADGRG1 9289 adhesion G protein-coupled receptor G1 layer formation in cerebral cortex Biological process - ADI1 55256 acireductone dioxygenase 1 oxidoreductase activity Molecular function 15938715 ZNF76 7629 zinc finger protein 76 regulation of transcription from RNA polymerase II promoter Biological process 9705341 NCF1 653361 neutrophil cytosolic factor 1 antigen processing and presentation of exogenous peptide antigen via MHC class I Biological process - FOXC2 2303 forkhead box C2 mesoderm development Biological process 8674414 PAF1 54623 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) negative regulation of myeloid cell differentiation Biological process 20541477 MSH2 4436 mutS homolog 2 determination of adult lifespan Biological process - TRIM63 84676 tripartite motif containing 63, E3 ubiquitin protein ligase proteasome-mediated ubiquitin-dependent protein catabolic process Biological process - TRAF6 7189 TNF receptor-associated factor 6, E3 ubiquitin protein ligase mitogen-activated protein kinase kinase kinase binding Molecular function 10094049 PRKACA 5566 protein kinase, cAMP-dependent, catalytic, alpha calcium-mediated signaling using intracellular calcium source Biological process 23507255 UBB 7314 ubiquitin B MyD88-dependent toll-like receptor signaling pathway Biological process - SKIL 6498 SKI-like proto-oncogene positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage Biological process - EFS 10278 embryonal Fyn-associated substrate cell adhesion Biological process - BRSK2 9024 BR serine/threonine kinase 2 regulation of insulin secretion involved in cellular response to glucose stimulus Biological process - TRPM2 7226 transient receptor potential cation channel, subfamily M, member 2 ion transmembrane transport Biological process - SOX2 6657 SRY (sex determining region Y)-box 2 eye development Biological process 18285410 CIB1 10519 calcium and integrin binding 1 (calmyrin) negative regulation of protein kinase B signaling Biological process - DNAJC10 54431 DnaJ (Hsp40) homolog, subfamily C, member 10 oxidation-reduction process Biological process - IL13 3596 interleukin 13 protein binding Molecular function 18243101 PABPC1L2A 340529 poly(A) binding protein, cytoplasmic 1-like 2A RNA binding Molecular function - RTF1 23168 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) positive regulation of histone H3-K4 methylation Biological process - MERTK 10461 MER proto-oncogene, tyrosine kinase positive regulation of phagocytosis Biological process 18395422 PCDHGB6 56100 protocadherin gamma subfamily B, 6 plasma membrane Cellular component - CLK3 1198 CDC-like kinase 3 ATP binding Molecular function - TRAF3 7187 TNF receptor-associated factor 3 endosome Cellular component - GMFB 2764 glia maturation factor, beta locomotory behavior Biological process - UGT1A6 54578 UDP glucuronosyltransferase 1 family, polypeptide A6 flavonoid glucuronidation Biological process - SPTBN4 57731 spectrin, beta, non-erythrocytic 4 cytoplasm Cellular component - APP 351 amyloid beta (A4) precursor protein serine-type endopeptidase inhibitor activity Molecular function 10652580 RPLP2 6181 ribosomal protein, large, P2 membrane Cellular component 19946888 PTPRC 5788 protein tyrosine phosphatase, receptor type, C positive regulation of antigen receptor-mediated signaling pathway Biological process - MYO1F 4542 myosin IF negative regulation of cell adhesion Biological process - PTK6 5753 protein tyrosine kinase 6 innate immune response Biological process - TRPC3 7222 transient receptor potential cation channel, subfamily C, member 3 cytosol Cellular component - MYO6 4646 myosin VI membrane Cellular component 19946888 ACIN1 22985 apoptotic chromatin condensation inducer 1 nucleolus Cellular component - DNAJC17 55192 DnaJ (Hsp40) homolog, subfamily C, member 17 toxin transport Biological process - KDM1A 23028 lysine (K)-specific demethylase 1A positive regulation of megakaryocyte differentiation Biological process - RPS27A 6233 ribosomal protein S27a extracellular exosome Cellular component 19199708 HELZ 9931 helicase with zinc finger metabolic process Biological process - OR9A4 130075 olfactory receptor, family 9, subfamily A, member 4 detection of chemical stimulus involved in sensory perception of smell Biological process - PLN 5350 phospholamban blood circulation Biological process 8406504 NEGR1 257194 neuronal growth regulator 1 positive regulation of neuron projection development Biological process - SUCLG2 8801 succinate-CoA ligase, GDP-forming, beta subunit succinyl-CoA metabolic process Biological process 9765291 PCP2 126006 Purkinje cell protein 2 guanyl-nucleotide exchange factor activity Molecular function - AKT1 207 v-akt murine thymoma viral oncogene homolog 1 positive regulation of glucose import Biological process 16814735 ARSG 22901 arylsulfatase G sulfur compound metabolic process Biological process 18283100 OPN1MW 2652 opsin 1 (cone pigments), medium-wave-sensitive retinoid metabolic process Biological process - RGS9 8787 regulator of G-protein signaling 9 nucleus Cellular component - RPS27A 6233 ribosomal protein S27a nucleotide-binding oligomerization domain containing signaling pathway Biological process - OCLN 100506658 occludin protein domain specific binding Molecular function 20164257 CIB1 10519 calcium and integrin binding 1 (calmyrin) Golgi apparatus Cellular component - NEU1 4758 sialidase 1 (lysosomal sialidase) exo-alpha-(2->3)-sialidase activity Molecular function - ARHGAP36 158763 Rho GTPase activating protein 36 GTPase activator activity Molecular function - PPP1R26 9858 protein phosphatase 1, regulatory subunit 26 phosphatase binding Molecular function 19389623 ABCG2 9429 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) protein binding Molecular function 18056989 AAK1 22848 AP2 associated kinase 1 clathrin-coated vesicle Cellular component - ARFGEF1 10565 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) endomembrane system organization Biological process 20360857 PIGM 93183 phosphatidylinositol glycan anchor biosynthesis, class M post-translational protein modification Biological process - ATP6V1E2 90423 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2 cytosol Cellular component - TENM4 26011 teneurin transmembrane protein 4 neuron projection Cellular component - SPATA5 166378 spermatogenesis associated 5 spermatogenesis Biological process - MTMR6 9107 myotubularin related protein 6 cytosol Cellular component - SLC11A1 6556 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 late endosome Cellular component - B9D1 27077 B9 protein domain 1 neuroepithelial cell differentiation Biological process - TMBIM1 64114 transmembrane BAX inhibitor motif containing 1 extracellular exosome Cellular component 19056867 PRDX1 5052 peroxiredoxin 1 response to reactive oxygen species Biological process - TFDP2 7029 transcription factor Dp-2 (E2F dimerization partner 2) transforming growth factor beta receptor signaling pathway Biological process - OR51B5 282763 olfactory receptor, family 51, subfamily B, member 5 integral component of membrane Cellular component 11121057 PSEN1 5663 presenilin 1 neuron development Biological process - NUMA1 4926 nuclear mitotic apparatus protein 1 cytosol Cellular component - MTDH 92140 metadherin integral component of membrane Cellular component - IL2RA 3559 interleukin 2 receptor, alpha plasma membrane Cellular component - CHKA 1119 choline kinase alpha choline kinase activity Molecular function 19915674 TMBIM6 7009 transmembrane BAX inhibitor motif containing 6 cytoplasm Cellular component 9660918 NCOA6 23054 nuclear receptor coactivator 6 retinoid X receptor binding Molecular function 11443112 KDELR1 10945 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 COPI-coated vesicle membrane Cellular component - STK11 6794 serine/threonine kinase 11 positive regulation of gluconeogenesis Biological process - CYBA 1535 cytochrome b-245, alpha polypeptide response to drug Biological process - CLIC2 1193 chloride intracellular channel 2 intracellular Cellular component - FOS 2353 FBJ murine osteosarcoma viral oncogene homolog response to corticosterone Biological process - ZNF16 7564 zinc finger protein 16 sequence-specific DNA binding transcription factor activity Molecular function - ABCA2 20 ATP-binding cassette, sub-family A (ABC1), member 2 regulation of intracellular cholesterol transport Biological process 15238223 NOX5 79400 NADPH oxidase, EF-hand calcium binding domain 5 superoxide-generating NADPH oxidase activity Molecular function 11483596 PLA2G4F 255189 phospholipase A2, group IVF phosphatidylinositol acyl-chain remodeling Biological process - DCT 1638 dopachrome tautomerase epidermis development Biological process 8206391 PPIL6 285755 peptidylprolyl isomerase (cyclophilin)-like 6 peptidyl-prolyl cis-trans isomerase activity Molecular function - PADI1 29943 peptidyl arginine deiminase, type I protein citrullination Biological process - DLG4 1742 discs, large homolog 4 (Drosophila) basolateral plasma membrane Cellular component - DVL3 1857 dishevelled segment polarity protein 3 protease binding Molecular function 20227366 VAMP2 6844 vesicle-associated membrane protein 2 (synaptobrevin 2) vesicle-mediated transport Biological process - SNX5 27131 sorting nexin 5 ruffle Cellular component - KRTAP26-1 388818 keratin associated protein 26-1 intermediate filament Cellular component - PSMC4 5704 proteasome (prosome, macropain) 26S subunit, ATPase, 4 membrane Cellular component 19946888 DHX15 1665 DEAH (Asp-Glu-Ala-His) box helicase 15 nucleus Cellular component - CHPT1 56994 choline phosphotransferase 1 diacylglycerol cholinephosphotransferase activity Molecular function - ABCC13 150000 ATP-binding cassette, sub-family C (CFTR/MRP), member 13, pseudogene transmembrane transport Biological process - KCNQ1 3784 potassium channel, voltage gated KQT-like subfamily Q, member 1 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization Molecular function 12522251 TMEM229A 730130 transmembrane protein 229A integral component of membrane Cellular component - GSTZ1 2954 glutathione S-transferase zeta 1 cytosol Cellular component - TMEM79 84283 transmembrane protein 79 establishment of skin barrier Biological process - AGTR2 186 angiotensin II receptor, type 2 negative regulation of blood vessel endothelial cell migration Biological process 15710780 DPH3 285381 diphthamide biosynthesis 3 cellular protein metabolic process Biological process - INS 3630 insulin protein binding Molecular function 9388210 KLK5 25818 kallikrein-related peptidase 5 extracellular space Cellular component 10608802 PTGDR 5729 prostaglandin D2 receptor (DP) sleep Biological process - DNAJB1 3337 DnaJ (Hsp40) homolog, subfamily B, member 1 Hsp70 protein binding Molecular function 23921388 PARK2 5071 parkin RBR E3 ubiquitin protein ligase kinase binding Molecular function 17512523 EAF1 85403 ELL associated factor 1 Cajal body Cellular component - EFNA2 1943 ephrin-A2 perikaryon Cellular component - EREG 2069 epiregulin neurotrophin TRK receptor signaling pathway Biological process - ST3GAL2 6483 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 dolichol-linked oligosaccharide biosynthetic process Biological process - OGFR 11054 opioid growth factor receptor membrane Cellular component - CFAP20 29105 cilia and flagella associated protein 20 ciliary basal body Cellular component 20118210 UBE2E1 7324 ubiquitin-conjugating enzyme E2E 1 ISG15 transferase activity Molecular function 16428300 AGPAT9 84803 1-acylglycerol-3-phosphate O-acyltransferase 9 cellular lipid metabolic process Biological process - PRAMEF15 653619 PRAME family member 15 positive regulation of cell proliferation Biological process - CANX 821 calnexin glycoprotein binding Molecular function - ZIC3 7547 Zic family member 3 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function 17764085 MYH7 4625 myosin, heavy chain 7, cardiac muscle, beta actin binding Molecular function - VEZF1 7716 vascular endothelial zinc finger 1 metal ion binding Molecular function - TP53 7157 tumor protein p53 receptor tyrosine kinase binding Molecular function 23027130 ATAD1 84896 ATPase family, AAA domain containing 1 negative regulation of synaptic transmission, glutamatergic Biological process - OR8U1 219417 olfactory receptor, family 8, subfamily U, member 1 detection of chemical stimulus involved in sensory perception of smell Biological process - POLN 353497 polymerase (DNA directed) nu nucleolus Cellular component 12794064 OR56B4 196335 olfactory receptor, family 56, subfamily B, member 4 G-protein coupled receptor activity Molecular function - BAP1 8314 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) cytoplasm Cellular component - CRIM1 51232 cysteine rich transmembrane BMP regulator 1 (chordin-like) regulation of cell growth Biological process - LTBP2 4053 latent transforming growth factor beta binding protein 2 extracellular exosome Cellular component 21362503 DNAH2 146754 dynein, axonemal, heavy chain 2 ATPase activity Molecular function - TRPC4 7223 transient receptor potential cation channel, subfamily C, member 4 ion transmembrane transport Biological process - HDAC4 9759 histone deacetylase 4 transcription corepressor activity Molecular function - RAB2A 5862 RAB2A, member RAS oncogene family Golgi membrane Cellular component - PARD3 56288 par-3 family cell polarity regulator asymmetric cell division Biological process 10934474 SNW1 22938 SNW domain containing 1 nucleus Cellular component 15878163 ACIN1 22985 apoptotic chromatin condensation inducer 1 nucleotide binding Molecular function - DOCK4 9732 dedicator of cytokinesis 4 stereocilium Cellular component 16464467 HIST1H4D 8360 histone cluster 1, H4d negative regulation of gene expression, epigenetic Biological process - DDN 23109 dendrin nucleus Cellular component - MMAA 166785 methylmalonic aciduria (cobalamin deficiency) cblA type small molecule metabolic process Biological process - PRSS50 29122 protease, serine, 50 serine-type endopeptidase activity Molecular function - HSPA6 3310 heat shock 70kDa protein 6 (HSP70B') extracellular exosome Cellular component 19199708 TRIP12 9320 thyroid hormone receptor interactor 12 cellular response to DNA damage stimulus Biological process 22884692 TRIM63 84676 tripartite motif containing 63, E3 ubiquitin protein ligase microtubule Cellular component 11243782 MIOS 54468 missing oocyte, meiosis regulator, homolog (Drosophila) cytoplasm Cellular component - IL17A 3605 interleukin 17A cellular response to interleukin-1 Biological process - GJA10 84694 gap junction protein, alpha 10, 62kDa synaptic transmission Biological process - TCIRG1 10312 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 vacuolar proton-transporting V-type ATPase complex Cellular component - AGPS 8540 alkylglycerone phosphate synthase nucleolus Cellular component - S100A10 6281 S100 calcium binding protein A10 protein heterotetramerization Biological process 23091277 LDLRAP1 26119 low density lipoprotein receptor adaptor protein 1 signaling adaptor activity Molecular function 12221107 TAF11 6882 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa transcription from RNA polymerase II promoter Biological process - CPXM1 56265 carboxypeptidase X (M14 family), member 1 metallocarboxypeptidase activity Molecular function - TCAP 8557 titin-cap structural constituent of muscle Molecular function 9817758 CDC42 998 cell division cycle 42 cytoplasmic ribonucleoprotein granule Cellular component 15121898 HELLS 3070 helicase, lymphoid-specific nucleus Cellular component - DUSP7 1849 dual specificity phosphatase 7 toll-like receptor TLR1:TLR2 signaling pathway Biological process - PODXL2 50512 podocalyxin-like 2 integral component of plasma membrane Cellular component 10722749 GPR55 9290 G protein-coupled receptor 55 bone resorption Biological process 19805329 TCF7L2 6934 transcription factor 7-like 2 (T-cell specific, HMG-box) cell proliferation Biological process 12408868 ANK2 287 ankyrin 2, neuronal positive regulation of potassium ion transport Biological process - FKBP1B 2281 FK506 binding protein 1B, 12.6 kDa cytosolic calcium ion homeostasis Biological process 22087651 UGT2B11 10720 UDP glucuronosyltransferase 2 family, polypeptide B11 xenobiotic metabolic process Biological process 8333863 SLC25A27 9481 solute carrier family 25, member 27 negative regulation of mitochondrial membrane potential Biological process - GRK5 2869 G protein-coupled receptor kinase 5 protein autophosphorylation Biological process 14976207 GPR141 353345 G protein-coupled receptor 141 G-protein coupled receptor activity Molecular function - YAP1 10413 Yes-associated protein 1 keratinocyte differentiation Biological process - ETFDH 2110 electron-transferring-flavoprotein dehydrogenase ubiquinone binding Molecular function 14640977 CAMK2G 818 calcium/calmodulin-dependent protein kinase II gamma synaptic transmission Biological process - EIF2AK3 9451 eukaryotic translation initiation factor 2-alpha kinase 3 negative regulation of translational initiation in response to stress Biological process 10677345 PIGW 284098 phosphatidylinositol glycan anchor biosynthesis, class W integral component of membrane Cellular component - CBLC 23624 Cbl proto-oncogene C, E3 ubiquitin protein ligase nucleus Cellular component - APOA4 337 apolipoprotein A-IV small molecule metabolic process Biological process - BDNF 627 brain-derived neurotrophic factor cellular response to norepinephrine stimulus Biological process - CCL19 6363 chemokine (C-C motif) ligand 19 CCR chemokine receptor binding Molecular function 20002784 TXN 7295 thioredoxin response to radiation Biological process 11118054 TRAF4 9618 TNF receptor-associated factor 4 bicellular tight junction Cellular component - NKX2-1 7080 NK2 homeobox 1 developmental induction Biological process - ACSF3 197322 acyl-CoA synthetase family member 3 ATP binding Molecular function - HIST2H3A 333932 histone cluster 2, H3a protein heterodimerization activity Molecular function - NAP1L4 4676 nucleosome assembly protein 1-like 4 cytoplasm Cellular component 9325046 ACVR2A 92 activin A receptor, type IIA regulation of nitric-oxide synthase activity Biological process - ADAM10 102 ADAM metallopeptidase domain 10 zinc ion binding Molecular function - KCNA5 3741 potassium channel, voltage gated shaker related subfamily A, member 5 Golgi apparatus Cellular component 16780588 VPS4A 27183 vacuolar protein sorting 4 homolog A (S. cerevisiae) midbody Cellular component 17853893 RBPMS 11030 RNA binding protein with multiple splicing nucleoplasm Cellular component - SRY 6736 sex determining region Y negative regulation of transcription from RNA polymerase II promoter Biological process - KIF1B 23095 kinesin family member 1B kinesin binding Molecular function 10341097 NOG 9241 noggin BMP signaling pathway Biological process - SYDE2 84144 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) cytosol Cellular component - TSHZ3 57616 teashirt zinc finger homeobox 3 in utero embryonic development Biological process - PEX11A 8800 peroxisomal biogenesis factor 11 alpha peroxisome organization Biological process 9792670 USP17L22 100287513 ubiquitin specific peptidase 17-like family member 22 protein deubiquitination Biological process - GLI3 2737 GLI family zinc finger 3 smoothened signaling pathway Biological process 11001584 COL1A2 1278 collagen, type I, alpha 2 blood vessel development Biological process 17211858 LY6K 54742 lymphocyte antigen 6 complex, locus K extracellular region Cellular component - HAUS6 54801 HAUS augmin-like complex, subunit 6 centrosome Cellular component 21399614 CD83 9308 CD83 molecule signal transduction Biological process 9310491 PRKAR2B 5577 protein kinase, cAMP-dependent, regulatory, type II, beta signal transduction Biological process - PAX6 5080 paired box 6 central nervous system development Biological process 10747901 HMGA1 3159 high mobility group AT-hook 1 protein binding Molecular function 10428834 PI4KB 5298 phosphatidylinositol 4-kinase, catalytic, beta phosphatidylinositol biosynthetic process Biological process - ZNF740 283337 zinc finger protein 740 metal ion binding Molecular function - RAB7B 338382 RAB7B, member RAS oncogene family GTP binding Molecular function - CALM3 808 calmodulin 3 (phosphorylase kinase, delta) regulation of cardiac muscle contraction Biological process 23040497 CATSPER2 117155 cation channel, sperm associated 2 single fertilization Biological process - FAM166A 401565 family with sequence similarity 166, member A nucleus Cellular component 21630459 KCNN3 3782 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 small conductance calcium-activated potassium channel activity Molecular function - ABR 29 active BCR-related actin cytoskeleton organization Biological process - AP5B1 91056 adaptor-related protein complex 5, beta 1 subunit AP-type membrane coat adaptor complex Cellular component 22022230 HAUS6 54801 HAUS augmin-like complex, subunit 6 mitotic nuclear division Biological process - AXIN1 8312 axin 1 nucleocytoplasmic transport Biological process - SLC25A5 292 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 ubiquitin protein ligase binding Molecular function 19725078 WIBG 84305 within bgcn homolog (Drosophila) cytoplasm Cellular component - FCER1A 2205 Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide serotonin secretion Biological process - HIST1H2BI 8346 histone cluster 1, H2bi defense response to Gram-positive bacterium Biological process 12860195 PDZK1 5174 PDZ domain containing 1 regulation of anion transport Biological process - IFITM3 10410 interferon induced transmembrane protein 3 negative regulation of viral entry into host cell Biological process 23358889 HMHA1 23526 histocompatibility (minor) HA-1 metal ion binding Molecular function - PARK7 11315 parkinson protein 7 plasma membrane Cellular component - KIFAP3 22920 kinesin-associated protein 3 endoplasmic reticulum Cellular component - SH3BP4 23677 SH3-domain binding protein 4 negative regulation of cell proliferation Biological process 22575674 TPR 7175 translocated promoter region, nuclear basket protein positive regulation of protein export from nucleus Biological process - FOXE3 2301 forkhead box E3 sequence-specific DNA binding transcription factor activity Molecular function 8825632 KLRC2 3822 killer cell lectin-like receptor subfamily C, member 2 cellular defense response Biological process 9683661 KIF14 9928 kinesin family member 14 ATPase activity Molecular function - RER1 11079 retention in endoplasmic reticulum sorting receptor 1 Golgi apparatus Cellular component - NR2F6 2063 nuclear receptor subfamily 2, group F, member 6 zinc ion binding Molecular function - PSMD9 5715 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 viral process Biological process - OPCML 4978 opioid binding protein/cell adhesion molecule-like extracellular exosome Cellular component 23376485 VAMP2 6844 vesicle-associated membrane protein 2 (synaptobrevin 2) protein complex assembly Biological process - SHPRH 257218 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase nucleosome assembly Biological process - NPC1 4864 Niemann-Pick disease, type C1 protein glycosylation Biological process 10821832 APCDD1 147495 adenomatosis polyposis coli down-regulated 1 hair follicle development Biological process 20393562 LOXL2 4017 lysyl oxidase-like 2 negative regulation of transcription, DNA-templated Biological process 16096638 TPH2 121278 tryptophan hydroxylase 2 neuron projection Cellular component - TAGLN3 29114 transgelin 3 negative regulation of transcription from RNA polymerase II promoter Biological process - GCH1 2643 GTP cyclohydrolase 1 GTP cyclohydrolase I activity Molecular function 11284739 CBX7 23492 chromobox homolog 7 methylated histone binding Molecular function - NPFFR2 10886 neuropeptide FF receptor 2 plasma membrane Cellular component - TAL2 6887 T-cell acute lymphocytic leukemia 2 thalamus development Biological process - AIFM3 150209 apoptosis-inducing factor, mitochondrion-associated, 3 oxidoreductase activity Molecular function - NOD2 64127 nucleotide-binding oligomerization domain containing 2 maintenance of gastrointestinal epithelium Biological process 17058067 DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) negative regulation of apoptotic process Biological process 15734730 NHLH1 4807 nescient helix loop helix 1 transcription, DNA-templated Biological process - DDO 8528 D-aspartate oxidase oxidation-reduction process Biological process - ZNF449 203523 zinc finger protein 449 nucleus Cellular component - PRSS8 5652 protease, serine, 8 proteolysis Biological process - TBX20 57057 T-box 20 negative regulation of transcription, DNA-templated Biological process - SDC3 9672 syndecan 3 extracellular matrix organization Biological process - TPM3 7170 tropomyosin 3 actin binding Molecular function - FBLN2 2199 fibulin 2 extracellular vesicle Cellular component 24769233 PLK2 10769 polo-like kinase 2 long-term synaptic potentiation Biological process - ERP29 10961 endoplasmic reticulum protein 29 negative regulation of gene expression Biological process 22064321 UCK1 83549 uridine-cytidine kinase 1 CTP salvage Biological process - SH3RF1 57630 SH3 domain containing ring finger 1 negative regulation of apoptotic process Biological process 21586138 ZNF20 7568 zinc finger protein 20 transcription, DNA-templated Biological process - ANGPT2 285 angiopoietin 2 maternal process involved in female pregnancy Biological process - AK7 122481 adenylate kinase 7 adenylate kinase activity Molecular function 21080915 CSK 1445 c-src tyrosine kinase adherens junction organization Biological process - LRP5 4041 low density lipoprotein receptor-related protein 5 regulation of bone remodeling Biological process - LILRB2 10288 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 cytoplasm Cellular component 19124746 GIMAP6 474344 GTPase, IMAP family member 6 cytosol Cellular component 23454188 PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide protein autophosphorylation Biological process 1646396 RABL3 285282 RAB, member of RAS oncogene family-like 3 GTP binding Molecular function - ATXN2L 11273 ataxin 2-like stress granule assembly Biological process 23209657 TCF19 6941 transcription factor 19 transcription, DNA-templated Biological process - UGT3A2 167127 UDP glycosyltransferase 3 family, polypeptide A2 glucuronosyltransferase activity Molecular function - SDHD 6392 succinate dehydrogenase complex, subunit D, integral membrane protein tricarboxylic acid cycle Biological process - ACTR3 10096 ARP3 actin-related protein 3 homolog (yeast) response to antibiotic Biological process - CNTN2 6900 contactin 2 (axonal) identical protein binding Molecular function 12963709 NQO1 1728 NAD(P)H dehydrogenase, quinone 1 extracellular exosome Cellular component 23376485 GAREM 64762 GRB2 associated, regulator of MAPK1 positive regulation of cell division Biological process - FKBP5 2289 FK506 binding protein 5 membrane Cellular component 19946888 LGMN 5641 legumain renal system process Biological process - NCOR1 9611 nuclear receptor corepressor 1 protein binding Molecular function 10049357 ARL14 80117 ADP-ribosylation factor-like 14 cytoplasmic membrane-bounded vesicle Cellular component - TWIST1 7291 twist family bHLH transcription factor 1 negative regulation of apoptotic process Biological process - RPH3A 22895 rabphilin 3A clathrin binding Molecular function - KIF22 3835 kinesin family member 22 antigen processing and presentation of exogenous peptide antigen via MHC class II Biological process - PPP3CA 5530 protein phosphatase 3, catalytic subunit, alpha isozyme Z disc Cellular component - ALAS1 211 5'-aminolevulinate synthase 1 5-aminolevulinate synthase activity Molecular function - UBR2 23304 ubiquitin protein ligase E3 component n-recognin 2 chromatin Cellular component - CYTH2 9266 cytohesin 2 endocytosis Biological process 9417041 DDX5 1655 DEAD (Asp-Glu-Ala-Asp) box helicase 5 regulation of osteoblast differentiation Biological process - SLX4 84464 SLX4 structure-specific endonuclease subunit 5'-flap endonuclease activity Molecular function 19595721 GRM2 2912 glutamate receptor, metabotropic 2 regulation of synaptic transmission, glutamatergic Biological process - LDLRAD4 753 low density lipoprotein receptor class A domain containing 4 negative regulation of SMAD protein complex assembly Biological process 24627487 PLA2G6 8398 phospholipase A2, group VI (cytosolic, calcium-independent) urinary bladder smooth muscle contraction Biological process - HIPK1 204851 homeodomain interacting protein kinase 1 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator Biological process - HIST1H2AI 8329 histone cluster 1, H2ai protein heterodimerization activity Molecular function - KIF5B 3799 kinesin family member 5B kinesin complex Cellular component - TNNT3 7140 troponin T type 3 (skeletal, fast) metabolic process Biological process 8987992 USP28 57646 ubiquitin specific peptidase 28 cellular response to DNA damage stimulus Biological process 17873522 GABARAPL2 11345 GABA(A) receptor-associated protein-like 2 beta-tubulin binding Molecular function - FNBP1L 54874 formin binding protein 1-like cytoskeleton Cellular component - ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like nucleus Cellular component 24005054 SASH1 23328 SAM and SH3 domain containing 1 positive regulation of NIK/NF-kappaB signaling Biological process 23776175 ABCA8 10351 ATP-binding cassette, sub-family A (ABC1), member 8 intracellular membrane-bounded organelle Cellular component - SDC1 6382 syndecan 1 cytoplasm Cellular component - ARHGEF25 115557 Rho guanine nucleotide exchange factor (GEF) 25 plasma membrane Cellular component - MLC1 23209 megalencephalic leukoencephalopathy with subcortical cysts 1 basolateral plasma membrane Cellular component 18165104 FGR 2268 FGR proto-oncogene, Src family tyrosine kinase immunoglobulin receptor binding Molecular function - C7orf49 78996 chromosome 7 open reading frame 49 protein binding Molecular function 25416956 KITLG 4254 KIT ligand positive regulation of MAP kinase activity Biological process - BAD 572 BCL2-associated agonist of cell death positive regulation of type B pancreatic cell development Biological process - MICALCL 84953 MICAL C-terminal like mitogen-activated protein kinase binding Molecular function - GCHFR 2644 GTP cyclohydrolase I feedback regulator dendrite Cellular component 16778797 ICAM1 3383 intercellular adhesion molecule 1 receptor activity Molecular function 2538243 EBF1 1879 early B-cell factor 1 sequence-specific DNA binding transcription factor activity Molecular function - PITPNM1 9600 phosphatidylinositol transfer protein, membrane-associated 1 phototransduction Biological process 9680295 SERPINA4 5267 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 extracellular space Cellular component 20551380 OR5V1 81696 olfactory receptor, family 5, subfamily V, member 1 G-protein coupled receptor activity Molecular function - FGF7 2252 fibroblast growth factor 7 growth factor activity Molecular function - HIVEP3 59269 human immunodeficiency virus type I enhancer binding protein 3 positive regulation of transcription, DNA-templated Biological process 15790681 RPF1 80135 ribosome production factor 1 homolog (S. cerevisiae) protein binding Molecular function 25416956 B4GALT7 11285 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 glycosaminoglycan biosynthetic process Biological process 10438455 GDNF 2668 glial cell derived neurotrophic factor positive regulation of ureteric bud formation Biological process 8657307 TSEN2 80746 TSEN2 tRNA splicing endonuclease subunit nucleolus Cellular component - DAB2 1601 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) negative regulation of extrinsic apoptotic signaling pathway Biological process - NRK 203447 Nik related kinase MAPK cascade Biological process - SLCO1A2 6579 solute carrier organic anion transporter family, member 1A2 organic anion transport Biological process 9007731 LIN7A 8825 lin-7 homolog A (C. elegans) synaptic transmission Biological process - SMNDC1 10285 survival motor neuron domain containing 1 spliceosomal complex assembly Biological process - NCL 4691 nucleolin positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter Biological process 24071584 KCNA1 3736 potassium channel, voltage gated shaker related subfamily A, member 1 regulation of ion transmembrane transport Biological process - FBLIM1 54751 filamin binding LIM protein 1 protein binding Molecular function 25416956 RFX3 5991 regulatory factor X, 3 (influences HLA class II expression) cell maturation Biological process 20413507 T 6862 T, brachyury homolog (mouse) mesoderm development Biological process 8963900 ACER1 125981 alkaline ceramidase 1 response to alkaline pH Biological process 17713573 DRG1 4733 developmentally regulated GTP binding protein 1 protein binding Molecular function 16189514 USP17L13 100287238 ubiquitin specific peptidase 17-like family member 13 endoplasmic reticulum Cellular component - JAG2 3714 jagged 2 epithelial cell apoptotic process involved in palatal shelf morphogenesis Biological process - NFYA 4800 nuclear transcription factor Y, alpha transcription cofactor binding Molecular function - H3F3B 3021 H3 histone, family 3B (H3.3B) RNA polymerase II distal enhancer sequence-specific DNA binding Molecular function 19633671 RHBDF1 64285 rhomboid 5 homolog 1 (Drosophila) endoplasmic reticulum membrane Cellular component 18832597 HIST1H3G 8355 histone cluster 1, H3g regulation of gene silencing Biological process 16267050 PPIAL4A 653505 peptidylprolyl isomerase A (cyclophilin A)-like 4A cytoplasm Cellular component - IL12B 3593 interleukin 12B interleukin-12 receptor binding Molecular function 9603733 BHMT2 23743 betaine--homocysteine S-methyltransferase 2 amino-acid betaine metabolic process Biological process 18230605 AGRP 181 agouti related neuropeptide neuronal cell body Cellular component - TRAPPC8 22878 trafficking protein particle complex 8 peroxisome degradation Biological process - ZNF207 7756 zinc finger protein 207 condensed chromosome kinetochore Cellular component - RUNX2 860 runt-related transcription factor 2 transcription factor complex Cellular component - MID1IP1 58526 MID1 interacting protein 1 negative regulation of microtubule depolymerization Biological process - MALL 7851 mal, T-cell differentiation protein-like integral component of membrane Cellular component - BRAF 673 B-Raf proto-oncogene, serine/threonine kinase small GTPase mediated signal transduction Biological process - OPRD1 4985 opioid receptor, delta 1 regulation of sensory perception of pain Biological process - POU6F1 5463 POU class 6 homeobox 1 sequence-specific DNA binding transcription factor activity Molecular function - ELOVL5 60481 ELOVL fatty acid elongase 5 dendritic tree Cellular component 25065913 DMRT3 58524 doublesex and mab-3 related transcription factor 3 adult walking behavior Biological process - ZNF358 140467 zinc finger protein 358 nucleus Cellular component - KEAP1 9817 kelch-like ECH-associated protein 1 transcription factor binding Molecular function 17015834 AREG 374 amphiregulin epidermal growth factor receptor binding Molecular function - CDKN1A 1026 cyclin-dependent kinase inhibitor 1A (p21, Cip1) response to X-ray Biological process - INHA 3623 inhibin, alpha response to external stimulus Biological process 10320815 OR2A12 346525 olfactory receptor, family 2, subfamily A, member 12 detection of chemical stimulus involved in sensory perception of smell Biological process - IL9R 3581 interleukin 9 receptor interleukin-9-mediated signaling pathway Biological process - PDHA2 5161 pyruvate dehydrogenase (lipoamide) alpha 2 tricarboxylic acid cycle Biological process - EYA2 2139 EYA transcriptional coactivator and phosphatase 2 DNA repair Biological process - CTSG 1511 cathepsin G protein phosphorylation Biological process 8573071 BTG2 7832 BTG family, member 2 positive regulation of transcription from RNA polymerase II promoter Biological process - CASP8 841 caspase 8, apoptosis-related cysteine peptidase cellular response to organic cyclic compound Biological process - CXCR6 10663 chemokine (C-X-C motif) receptor 6 chemokine-mediated signaling pathway Biological process - BECN1 8678 beclin 1, autophagy related phosphatidylinositol 3-kinase complex, class III, type I Cellular component - CUL5 8065 cullin 5 cell proliferation Biological process 9037604 YBX1 4904 Y box binding protein 1 nuclear membrane Cellular component - ETFA 2108 electron-transfer-flavoprotein, alpha polypeptide electron carrier activity Molecular function 10423253 KRT19 3880 keratin 19, type I protein binding Molecular function 15846844 PRPF38A 84950 pre-mRNA processing factor 38A RNA splicing Biological process - ZBTB38 253461 zinc finger and BTB domain containing 38 protein homodimerization activity Molecular function 16354688 PKD2L1 9033 polycystic kidney disease 2-like 1 cation transmembrane transporter activity Molecular function - NPPA 4878 natriuretic peptide A cardiac muscle hypertrophy in response to stress Biological process - PDE3A 5139 phosphodiesterase 3A, cGMP-inhibited negative regulation of vascular permeability Biological process 17704206 TSNAXIP1 55815 translin-associated factor X interacting protein 1 cellular_component Cellular component - ZNF277 11179 zinc finger protein 277 transcription, DNA-templated Biological process - RILPL1 353116 Rab interacting lysosomal protein-like 1 primary cilium Cellular component - CDC25C 995 cell division cycle 25C protein kinase binding Molecular function 14968113 ZBTB2 57621 zinc finger and BTB domain containing 2 DNA binding Molecular function - LIF 3976 leukemia inhibitory factor cytokine activity Molecular function 7957045 BSPRY 54836 B-box and SPRY domain containing perinuclear region of cytoplasm Cellular component - CIR1 9541 corepressor interacting with RBPJ, 1 regulation of transcription from RNA polymerase II promoter Biological process 18663143 CCDC107 203260 coiled-coil domain containing 107 integral component of membrane Cellular component - CDAN1 146059 codanin 1 cytoplasm Cellular component - POSTN 10631 periostin, osteoblast specific factor regulation of Notch signaling pathway Biological process - SESN3 143686 sestrin 3 response to insulin Biological process - ZNF445 353274 zinc finger protein 445 sequence-specific DNA binding transcription factor activity Molecular function - GRPEL2 134266 GrpE-like 2, mitochondrial (E. coli) mitochondrial inner membrane Cellular component - HTT 3064 huntingtin cell aging Biological process - AGPAT6 137964 1-acylglycerol-3-phosphate O-acyltransferase 6 diacylglycerol metabolic process Biological process - IFT57 55081 intraflagellar transport 57 photoreceptor connecting cilium Cellular component - TOM1L2 146691 target of myb1-like 2 (chicken) protein binding Molecular function 16412388 NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 negative regulation of transcription from RNA polymerase II promoter Biological process 19881551 KCNK13 56659 potassium channel, two pore domain subfamily K, member 13 plasma membrane Cellular component - PPP1CA 5499 protein phosphatase 1, catalytic subunit, alpha isozyme entrainment of circadian clock by photoperiod Biological process - FABP4 2167 fatty acid binding protein 4, adipocyte nucleus Cellular component - SLC26A1 10861 solute carrier family 26 (anion exchanger), member 1 chloride transmembrane transport Biological process - SRFBP1 153443 serum response factor binding protein 1 transcription, DNA-templated Biological process - RAPGEF4 11069 Rap guanine nucleotide exchange factor (GEF) 4 small GTPase mediated signal transduction Biological process - RHOU 58480 ras homolog family member U Golgi membrane Cellular component - NUP98 4928 nucleoporin 98kDa cellular protein metabolic process Biological process - SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) rough endoplasmic reticulum Cellular component - CDCA8 55143 cell division cycle associated 8 chromosome passenger complex Cellular component 15260989 FXYD6 53826 FXYD domain containing ion transport regulator 6 transmembrane transport Biological process - KLF12 11278 Kruppel-like factor 12 transcription, DNA-templated Biological process - TSTA3 7264 tissue specific transplantation antigen P35B cytoplasm Cellular component 11698403 RAMP3 10268 receptor (G protein-coupled) activity modifying protein 3 receptor activity Molecular function 10882736 SYT1 6857 synaptotagmin I synaptic transmission Biological process - RNF168 165918 ring finger protein 168, E3 ubiquitin protein ligase cellular response to DNA damage stimulus Biological process 19500350 ALDOC 230 aldolase C, fructose-bisphosphate extracellular exosome Cellular component 19056867 FKBP11 51303 FK506 binding protein 11, 19 kDa membrane Cellular component 19946888 PAFAH1B1 5048 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) protein homodimerization activity Molecular function - TMCC3 57458 transmembrane and coiled-coil domain family 3 integral component of membrane Cellular component - HSCB 150274 HscB mitochondrial iron-sulfur cluster co-chaperone mitochondrion Cellular component 12938016 BAD 572 BCL2-associated agonist of cell death response to glucocorticoid Biological process - ACVR1C 130399 activin A receptor, type IC nodal signaling pathway Biological process 15150278 CYP26A1 1592 cytochrome P450, family 26, subfamily A, polypeptide 1 small molecule metabolic process Biological process - PSMA1 5682 proteasome (prosome, macropain) subunit, alpha type, 1 cytosol Cellular component - PSEN2 5664 presenilin 2 lung alveolus development Biological process - PLCB2 5330 phospholipase C, beta 2 phospholipid metabolic process Biological process 1644792 NPTN 27020 neuroplastin peptidyl-tyrosine phosphorylation Biological process - JCHAIN 3512 joining chain of multimeric IgA and IgM antibacterial humoral response Biological process 23250751 PSME4 23198 proteasome (prosome, macropain) activator subunit 4 innate immune response Biological process - AKAP10 11216 A kinase (PRKA) anchor protein 10 cytosol Cellular component - NAA38 84316 N(alpha)-acetyltransferase 38, NatC auxiliary subunit polysome Cellular component 19398576 SCNN1D 6339 sodium channel, non voltage gated 1 delta subunit actin cytoskeleton Cellular component - ATP2B2 491 ATPase, Ca++ transporting, plasma membrane 2 cGMP metabolic process Biological process - ESR1 2099 estrogen receptor 1 protein binding Molecular function 10359819 HTR4 3360 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled membrane Cellular component 16102731 WDR82 80335 WD repeat domain 82 histone methyltransferase activity (H3-K4 specific) Molecular function 17355966 CLVS1 157807 clavesin 1 lysosome organization Biological process - GABBR1 2550 gamma-aminobutyric acid (GABA) B receptor, 1 postsynaptic membrane Cellular component - EIF5A2 56648 eukaryotic translation initiation factor 5A2 translational frameshifting Biological process - CRYBA1 1411 crystallin, beta A1 structural constituent of eye lens Molecular function - ACAD8 27034 acyl-CoA dehydrogenase family, member 8 valine catabolic process Biological process - REEP1 65055 receptor accessory protein 1 olfactory receptor binding Molecular function 15550249 SLK 9748 STE20-like kinase signal transduction by protein phosphorylation Biological process - FEV 54738 FEV (ETS oncogene family) neuron fate specification Biological process - RSPO2 340419 R-spondin 2 trachea cartilage morphogenesis Biological process - PLIN2 123 perilipin 2 lipid particle Cellular component 14741744 ZNF346 23567 zinc finger protein 346 double-stranded RNA binding Molecular function 10488071 MET 4233 MET proto-oncogene, receptor tyrosine kinase brain development Biological process - TNPO1 3842 transportin 1 organelle organization Biological process - KAT8 84148 K(lysine) acetyltransferase 8 regulation of autophagy Biological process 23863932 CDK8 1024 cyclin-dependent kinase 8 RNA polymerase II carboxy-terminal domain kinase activity Molecular function - MT1G 4495 metallothionein 1G cellular response to copper ion Biological process 3403543 PABPC1 26986 poly(A) binding protein, cytoplasmic 1 nuclear-transcribed mRNA poly(A) tail shortening Biological process - POLR1C 9533 polymerase (RNA) I polypeptide C, 30kDa regulation of gene expression, epigenetic Biological process - ATP5F1 515 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 mitochondrial proton-transporting ATP synthase complex Cellular component 12110673 STX5 6811 syntaxin 5 retrograde transport, endosome to Golgi Biological process 15215310 AQP1 358 aquaporin 1 (Colton blood group) cellular hyperosmotic response Biological process 11922632 UBE2L3 7332 ubiquitin-conjugating enzyme E2L 3 nucleus Cellular component - ELP3 55140 elongator acetyltransferase complex subunit 3 histone H3 acetylation Biological process 11714725 SIX1 6495 SIX homeobox 1 nucleolus Cellular component - ZNF473 25888 zinc finger protein 473 nucleoplasm Cellular component - RPL30 6156 ribosomal protein L30 viral transcription Biological process - TSC2 7249 tuberous sclerosis 2 TSC1-TSC2 complex Cellular component 9580671 UNC13B 10497 unc-13 homolog B (C. elegans) synaptic vesicle docking Biological process - GALNT15 117248 polypeptide N-acetylgalactosaminyltransferase 15 O-glycan processing Biological process - REL 5966 v-rel avian reticuloendotheliosis viral oncogene homolog sequence-specific DNA binding transcription factor activity Molecular function 8423996 DAG1 1605 dystroglycan 1 (dystrophin-associated glycoprotein 1) plasma membrane Cellular component - FURIN 5045 furin (paired basic amino acid cleaving enzyme) secretion by cell Biological process 8615794 CPEB1 64506 cytoplasmic polyadenylation element binding protein 1 postsynaptic density Cellular component - CLEC4E 26253 C-type lectin domain family 4, member E positive regulation of cytokine secretion Biological process - TRAPPC8 22878 trafficking protein particle complex 8 ER to Golgi vesicle-mediated transport Biological process - DLG1 1739 discs, large homolog 1 (Drosophila) extracellular exosome Cellular component 20458337 P2RY12 64805 purinergic receptor P2Y, G-protein coupled, 12 plasma membrane Cellular component - E2F7 144455 E2F transcription factor 7 DNA damage response, signal transduction by p53 class mediator Biological process 22802528 CDC23 8697 cell division cycle 23 protein K11-linked ubiquitination Biological process 18485873 C1R 715 complement component 1, r subcomponent serine-type endopeptidase activity Molecular function - HK2 3099 hexokinase 2 response to ischemia Biological process - CHST10 9486 carbohydrate sulfotransferase 10 sulfotransferase activity Molecular function 9478973 DVL1 1855 dishevelled segment polarity protein 1 skeletal muscle acetylcholine-gated channel clustering Biological process - SKIL 6498 SKI-like proto-oncogene cytoplasm Cellular component 16109768 IFT20 90410 intraflagellar transport 20 centriole Cellular component - BZRAP1 9256 benzodiazepine receptor (peripheral) associated protein 1 biological_process Biological process - SOX2 6657 SRY (sex determining region Y)-box 2 positive regulation of cell-cell adhesion Biological process - COPS5 10987 COP9 signalosome subunit 5 positive regulation of transcription from RNA polymerase II promoter Biological process 16410250 IGFBP3 3486 insulin-like growth factor binding protein 3 protein binding Molecular function 14561895 TMEM110 375346 transmembrane protein 110 biological_process Biological process - HDAC4 9759 histone deacetylase 4 activating transcription factor binding Molecular function 10983972 IL27RA 9466 interleukin 27 receptor, alpha negative regulation of type 2 immune response Biological process - RAPH1 65059 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 cell-matrix adhesion Biological process - USP9Y 8287 ubiquitin specific peptidase 9, Y-linked cell migration Biological process - GUCY2D 3000 guanylate cyclase 2D, membrane (retina-specific) phototransduction, visible light Biological process - FAU 2197 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed translation Biological process - ANXA3 306 annexin A3 positive regulation of angiogenesis Biological process 16236264 TDRD12 91646 tudor domain containing 12 positive regulation of protein targeting to mitochondrion Biological process 24270810 APOA1 335 apolipoprotein A-I blood coagulation Biological process - CHM 1121 choroideremia (Rab escort protein 1) protein targeting to membrane Biological process 7957092 NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 vasculogenesis Biological process - ICAM2 3384 intercellular adhesion molecule 2 plasma membrane Cellular component - HDC 3067 histidine decarboxylase histidine metabolic process Biological process 1487235 CACNA1B 774 calcium channel, voltage-dependent, N type, alpha 1B subunit protein binding Molecular function 11438518 MYL9 10398 myosin, light chain 9, regulatory ephrin receptor signaling pathway Biological process - SLC6A17 388662 solute carrier family 6 (neutral amino acid transporter), member 17 integral component of plasma membrane Cellular component - EPCAM 4072 epithelial cell adhesion molecule protein binding Molecular function 16054130 TXNDC2 84203 thioredoxin domain containing 2 (spermatozoa) sulfate assimilation Biological process - RTN2 6253 reticulon 2 regulation of glucose import Biological process - TRIM38 10475 tripartite motif containing 38 ligase activity Molecular function - PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 TBP-class protein binding Molecular function - DNAAF1 123872 dynein, axonemal, assembly factor 1 inner dynein arm assembly Biological process 19944400 NOTCH1 4851 notch 1 spermatogenesis Biological process - STK17B 9262 serine/threonine kinase 17b endoplasmic reticulum-Golgi intermediate compartment Cellular component - ADRA1B 147 adrenoceptor alpha 1B positive regulation of the force of heart contraction by epinephrine-norepinephrine Biological process - FUT10 84750 fucosyltransferase 10 (alpha (1,3) fucosyltransferase) protein folding Biological process 11698403 TMEM43 79188 transmembrane protein 43 protein self-association Molecular function - APBA1 320 amyloid beta (A4) precursor protein-binding, family A, member 1 in utero embryonic development Biological process - TAGLN 6876 transgelin actin filament binding Molecular function - APLF 200558 aprataxin and PNKP like factor cytosol Cellular component - TGFB1 7040 transforming growth factor, beta 1 aging Biological process - FAM89B 23625 family with sequence similarity 89, member B transcription corepressor binding Molecular function - RACGAP1 29127 Rac GTPase activating protein 1 regulation of attachment of spindle microtubules to kinetochore Biological process 15642749 ATP8B3 148229 ATPase, aminophospholipid transporter, class I, type 8B, member 3 binding of sperm to zona pellucida Biological process - APOA1BP 128240 apolipoprotein A-I binding protein extracellular exosome Cellular component 23376485 ABCD1 215 ATP-binding cassette, sub-family D (ALD), member 1 identical protein binding Molecular function 10551832 PRKD2 25865 protein kinase D2 Golgi apparatus Cellular component - NDUFA3 4696 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa mitochondrial inner membrane Cellular component - HSPA5 3309 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) plasma membrane Cellular component - HPSE 10855 heparanase heparan sulfate proteoglycan catabolic process Biological process 12213822 JUN 3725 jun proto-oncogene response to cAMP Biological process - ARMCX5 64860 armadillo repeat containing, X-linked 5 protein binding Molecular function 25416956 GCKR 2646 glucokinase (hexokinase 4) regulator protein domain specific binding Molecular function - ARL2 402 ADP-ribosylation factor-like 2 mitochondrial matrix Cellular component - WNK1 65125 WNK lysine deficient protein kinase 1 ion transport Biological process - GDF10 2662 growth differentiation factor 10 SMAD protein signal transduction Biological process - PPIG 9360 peptidylprolyl isomerase G (cyclophilin G) peptidyl-prolyl cis-trans isomerase activity Molecular function - EPHA4 2043 EPH receptor A4 axon Cellular component - GPX1 2876 glutathione peroxidase 1 vasodilation Biological process - OR10J3 441911 olfactory receptor, family 10, subfamily J, member 3 detection of chemical stimulus involved in sensory perception Biological process - MPP1 4354 membrane protein, palmitoylated 1, 55kDa nucleotide phosphorylation Biological process 1310897 RB1 5925 retinoblastoma 1 androgen receptor signaling pathway Biological process 15572661 MCM7 4176 minichromosome maintenance complex component 7 cytoplasm Cellular component - HMP19 51617 HMP19 protein integral component of membrane Cellular component - TAF6L 10629 TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa regulation of transcription from RNA polymerase II promoter Biological process 9674425 KCNK1 3775 potassium channel, two pore domain subfamily K, member 1 potassium ion transmembrane transport Biological process 22282804 MVB12B 89853 multivesicular body subunit 12B lipid binding Molecular function 22232651 MOK 5891 MOK protein kinase signal transduction Biological process 10421840 HSPA1A 3303 heat shock 70kDa protein 1A ATPase activity Molecular function 23921388 RHOJ 57381 ras homolog family member J extracellular exosome Cellular component 23533145 PODXL 5420 podocalyxin-like slit diaphragm Cellular component - SMAD4 4089 SMAD family member 4 palate development Biological process - TGFBR2 7048 transforming growth factor, beta receptor II (70/80kDa) metal ion binding Molecular function - OR5T2 219464 olfactory receptor, family 5, subfamily T, member 2 G-protein coupled receptor signaling pathway Biological process - HTR1D 3352 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled synaptic transmission Biological process - KIF14 9928 kinesin family member 14 microtubule-based movement Biological process - RBM11 54033 RNA binding motif protein 11 protein binding Molecular function 25416956 BBS2 583 Bardet-Biedl syndrome 2 cilium assembly Biological process - CELSR2 1952 cadherin, EGF LAG seven-pass G-type receptor 2 regulation of protein localization Biological process - DEFB121 245934 defensin, beta 121 defense response to bacterium Biological process - TRAF2 7186 TNF receptor-associated factor 2 thioesterase binding Molecular function 11279055 IL1B 3553 interleukin 1, beta positive regulation of mitotic nuclear division Biological process 2989698 AGRN 375790 agrin dystroglycan binding Molecular function - GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa positive regulation of transcription from RNA polymerase II promoter Biological process 12750007 TRAT1 50852 T cell receptor associated transmembrane adaptor 1 signal transduction Biological process 9687533 GRAP2 9402 GRB2-related adaptor protein 2 protein binding Molecular function 12359715 CELF4 56853 CUGBP, Elav-like family member 4 BRE binding Molecular function - CEBPG 1054 CCAAT/enhancer binding protein (C/EBP), gamma immune response Biological process - CXCL5 6374 chemokine (C-X-C motif) ligand 5 immune response Biological process - IFT81 28981 intraflagellar transport 81 cilium assembly Biological process 23990561 ETFDH 2110 electron-transferring-flavoprotein dehydrogenase 4 iron, 4 sulfur cluster binding Molecular function 18037314 COX15 1355 cytochrome c oxidase assembly homolog 15 (yeast) cytochrome complex Cellular component 12474143 ZNF350 59348 zinc finger protein 350 nucleus Cellular component 23665872 CAPNS2 84290 calpain, small subunit 2 cytoplasm Cellular component - PINX1 54984 PIN2/TERF1 interacting, telomerase inhibitor 1 cytoplasm Cellular component - ADGRV1 84059 adhesion G protein-coupled receptor V1 myosin binding Molecular function - SLC7A1 6541 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 integral component of plasma membrane Cellular component 1718082 RGL2 5863 ral guanine nucleotide dissociation stimulator-like 2 protein binding Molecular function 25416956 HLA-DMB 3109 major histocompatibility complex, class II, DM beta integral component of membrane Cellular component - OR9Q1 219956 olfactory receptor, family 9, subfamily Q, member 1 G-protein coupled receptor signaling pathway Biological process - ZNF384 171017 zinc finger protein 384 nucleus Cellular component - NCOA1 8648 nuclear receptor coactivator 1 hypothalamus development Biological process - SLC9A3R1 9368 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 filopodium Cellular component - PMM1 5372 phosphomannomutase 1 post-translational protein modification Biological process - LRP4 4038 low density lipoprotein receptor-related protein 4 protein heterotetramerization Biological process - CIDEA 1149 cell death-inducing DFFA-like effector a negative regulation of cytokine secretion Biological process 15919794 HSP90AA1 3320 heat shock protein 90kDa alpha (cytosolic), class A member 1 organelle organization Biological process - PPIP5K2 23262 diphosphoinositol pentakisphosphate kinase 2 inositol hexakisphosphate 5-kinase activity Molecular function - NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 learning Biological process - IFNA5 3442 interferon, alpha 5 defense response to virus Biological process - SOD3 6649 superoxide dismutase 3, extracellular extracellular region Cellular component - XDH 7498 xanthine dehydrogenase small molecule metabolic process Biological process - FGF16 8823 fibroblast growth factor 16 Fc-epsilon receptor signaling pathway Biological process - FBXL4 26235 F-box and leucine-rich repeat protein 4 ubiquitin ligase complex Cellular component 10531035 RSPH14 27156 radial spoke head 14 homolog (Chlamydomonas) molecular_function Molecular function - PIP 5304 prolactin-induced protein actin binding Molecular function 2013294 HDAC7 51564 histone deacetylase 7 negative regulation of transcription from RNA polymerase II promoter Biological process - HSD3B7 80270 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 bile acid metabolic process Biological process - CNIH1 10175 cornichon family AMPA receptor auxiliary protein 1 signal transduction Biological process 10209299 ENPP7 339221 ectonucleotide pyrophosphatase/phosphodiesterase 7 sphingomyelin catabolic process Biological process - OR8G3P 387815 olfactory receptor, family 8, subfamily G, member 3 pseudogene olfactory receptor activity Molecular function - VAMP7 6845 vesicle-associated membrane protein 7 secretory granule Cellular component 18042464 UXT 8409 ubiquitously-expressed, prefoldin-like chaperone RNA polymerase II transcription corepressor activity Molecular function 21730289 CDH11 1009 cadherin 11, type 2, OB-cadherin (osteoblast) cell adhesion Biological process 8163513 XRCC4 7518 X-ray repair complementing defective repair in Chinese hamster cells 4 cellular response to lithium ion Biological process - FSHB 2488 follicle stimulating hormone, beta polypeptide transforming growth factor beta receptor signaling pathway Biological process 14557487 TAL2 6887 T-cell acute lymphocytic leukemia 2 regulation of transcription from RNA polymerase II promoter Biological process - KCNG3 170850 potassium channel, voltage gated modifier subfamily G, member 3 plasma membrane Cellular component - GALR3 8484 galanin receptor 3 plasma membrane Cellular component - FGF10 2255 fibroblast growth factor 10 cell surface Cellular component 11923311 PTEN 5728 phosphatase and tensin homolog negative regulation of synaptic vesicle clustering Biological process - OR52D1 390066 olfactory receptor, family 52, subfamily D, member 1 olfactory receptor activity Molecular function 11121057 UNC119 9094 unc-119 homolog (C. elegans) cytosol Cellular component 9538874 PTPRC 5788 protein tyrosine phosphatase, receptor type, C focal adhesion Cellular component - IFITM3 10410 interferon induced transmembrane protein 3 protein binding Molecular function 18486613 STXBP1 6812 syntaxin binding protein 1 mitochondrion Cellular component - MMS19 64210 MMS19 nucleotide excision repair homolog (S. cerevisiae) response to hormone Biological process 11279242 ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2 positive regulation of cell proliferation Biological process - PRSS8 5652 protease, serine, 8 plasma membrane Cellular component 19911255 BCL3 602 B-cell CLL/lymphoma 3 follicular dendritic cell differentiation Biological process - FUT9 10690 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) L-fucose catabolic process Biological process 11698403 TTPA 7274 tocopherol (alpha) transfer protein negative regulation of establishment of blood-brain barrier Biological process - TESK2 10420 testis-specific kinase 2 cytoplasm Cellular component - TMEM173 340061 transmembrane protein 173 protein binding Molecular function 18724357 RFNG 5986 RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity Molecular function - RRP1B 23076 ribosomal RNA processing 1B heterochromatin Cellular component - CERCAM 51148 cerebral endothelial cell adhesion molecule movement of cell or subcellular component Biological process 10608765 NME2 4831 NME/NM23 nucleoside diphosphate kinase 2 protein binding Molecular function 11919189 SOD2 6648 superoxide dismutase 2, mitochondrial superoxide dismutase activity Molecular function - HNF1B 6928 HNF1 homeobox B RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Molecular function - DRD1 1812 dopamine receptor D1 synaptic transmission, dopaminergic Biological process - PIK3R4 30849 phosphoinositide-3-kinase, regulatory subunit 4 ATP binding Molecular function - TUFM 7284 Tu translation elongation factor, mitochondrial GTPase activity Molecular function - SLC35B2 347734 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 xenobiotic metabolic process Biological process - ZNF8 7554 zinc finger protein 8 negative regulation of transcription from RNA polymerase II promoter Biological process - FGF6 2251 fibroblast growth factor 6 extracellular region Cellular component - CLCN5 1184 chloride channel, voltage-sensitive 5 transmembrane transport Biological process - APOA5 116519 apolipoprotein A-V positive regulation of very-low-density lipoprotein particle remodeling Biological process 18635818 UBE4A 9354 ubiquitination factor E4A cytoplasm Cellular component - SDC4 6385 syndecan 4 protein kinase C binding Molecular function - PRKCE 5581 protein kinase C, epsilon positive regulation of lipid catabolic process Biological process - LAMA3 3909 laminin, alpha 3 endodermal cell differentiation Biological process 23154389 POLR2C 5432 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa DNA-directed RNA polymerase II, core complex Cellular component 9852112 IL1RL2 8808 interleukin 1 receptor-like 2 interleukin-1-mediated signaling pathway Biological process - FOSL1 8061 FOS-like antigen 1 vitellogenesis Biological process - NEUROD2 4761 neuronal differentiation 2 positive regulation of synaptic plasticity Biological process - CX3CR1 1524 chemokine (C-X3-C motif) receptor 1 negative regulation of cell migration Biological process - PCF11 51585 PCF11 cleavage and polyadenylation factor subunit mRNA cleavage factor complex Cellular component 11060040 SLC16A10 117247 solute carrier family 16 (aromatic amino acid transporter), member 10 ion transport Biological process - ZFHX4 79776 zinc finger homeobox 4 transcription, DNA-templated Biological process - FOLR1 2348 folate receptor 1 (adult) receptor activity Molecular function 10633085 EOMES 8320 eomesodermin cerebral cortex regionalization Biological process - CLEC5A 23601 C-type lectin domain family 5, member A osteoblast development Biological process - KCNJ10 3766 potassium channel, inwardly rectifying subfamily J, member 10 identical protein binding Molecular function - PDE3A 5139 phosphodiesterase 3A, cGMP-inhibited cGMP-mediated signaling Biological process 17704206 PTPRZ1 5803 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 protein dephosphorylation Biological process 1323835 SLC30A5 64924 solute carrier family 30 (zinc transporter), member 5 regulation of proton transport Biological process 11937503 MRC1 4360 mannose receptor, C type 1 cellular response to lipopolysaccharide Biological process - SMR3B 10879 submaxillary gland androgen regulated protein 3B biological_process Biological process - OR5D18 219438 olfactory receptor, family 5, subfamily D, member 18 olfactory receptor activity Molecular function - MED30 90390 mediator complex subunit 30 stem cell maintenance Biological process - MAP3K11 4296 mitogen-activated protein kinase kinase kinase 11 protein tyrosine kinase activity Molecular function - APTX 54840 aprataxin response to hydrogen peroxide Biological process 15044383 EGF 1950 epidermal growth factor phosphatidylinositol-mediated signaling Biological process - RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function - CNGB1 1258 cyclic nucleotide gated channel beta 1 regulation of rhodopsin mediated signaling pathway Biological process - ATG7 10533 autophagy related 7 cerebral cortex development Biological process - CFAP126 257177 cilia and flagella associated protein 126 cytoplasm Cellular component - HDAC2 3066 histone deacetylase 2 negative regulation of transcription from RNA polymerase II promoter Biological process 19041327 SLX1B 79008 SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) metal ion binding Molecular function - VPS25 84313 vacuolar protein sorting 25 homolog (S. cerevisiae) regulation of viral life cycle Biological process 16973552 GTF2B 2959 general transcription factor IIB protein binding Molecular function 10330164 PHACTR4 65979 phosphatase and actin regulator 4 actin binding Molecular function - ARHGDIA 396 Rho GDP dissociation inhibitor (GDI) alpha positive regulation of axonogenesis Biological process - LATS2 26524 large tumor suppressor kinase 2 spindle pole Cellular component 12853976 PTGS2 5743 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) nucleus Cellular component - RTKN2 219790 rhotekin 2 hemopoiesis Biological process - HLCS 3141 holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) small molecule metabolic process Biological process - TSC1 7248 tuberous sclerosis 1 myelination Biological process - C4orf48 401115 chromosome 4 open reading frame 48 extracellular region Cellular component - THPO 7066 thrombopoietin thrombopoietin-mediated signaling pathway Biological process - CENPT 80152 centromere protein T cell division Biological process - ATP5F1 515 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 nucleus Cellular component 21630459 FBL 2091 fibrillarin poly(A) RNA binding Molecular function 22658674 TICAM2 353376 toll-like receptor adaptor molecule 2 Golgi apparatus Cellular component - KIR2DS1 3806 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 innate immune response Biological process - RASSF9 9182 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 cytosol Cellular component 9837933 NUP85 79902 nucleoporin 85kDa small GTPase mediated signal transduction Biological process - C14orf39 317761 chromosome 14 open reading frame 39 multicellular organismal development Biological process - PAH 5053 phenylalanine hydroxylase extracellular exosome Cellular component 23376485 POM121C 100101267 POM121 transmembrane nucleoporin C protein binding Molecular function 17577209 GTF2H3 2967 general transcription factor IIH, polypeptide 3, 34kDa transcription elongation from RNA polymerase I promoter Biological process - EFNA1 1942 ephrin-A1 axon guidance Biological process - TRPM7 54822 transient receptor potential cation channel, subfamily M, member 7 protein serine/threonine kinase activity Molecular function - SV2B 9899 synaptic vesicle glycoprotein 2B protein binding Molecular function 25416956 MSH2 4436 mutS homolog 2 MutSalpha complex Cellular component 23622243 SIRT2 22933 sirtuin 2 positive regulation of transcription from RNA polymerase II promoter Biological process - PRNP 5621 prion protein negative regulation of apoptotic process Biological process - MYL6 4637 myosin, light chain 6, alkali, smooth muscle and non-muscle extracellular exosome Cellular component 20458337 IFT172 26160 intraflagellar transport 172 positive regulation of smoothened signaling pathway Biological process - CHST11 50515 carbohydrate (chondroitin 4) sulfotransferase 11 chondroitin sulfate metabolic process Biological process - GRIN3B 116444 glutamate receptor, ionotropic, N-methyl-D-aspartate 3B N-methyl-D-aspartate selective glutamate receptor activity Molecular function - GLMN 11146 glomulin, FKBP associated protein positive regulation of interleukin-2 biosynthetic process Biological process 12604780 CD58 965 CD58 molecule cellular response to interferon-gamma Biological process 19109405 CDH16 1014 cadherin 16, KSP-cadherin cell adhesion Biological process 9721215 PRKDC 5591 protein kinase, DNA-activated, catalytic polypeptide T cell differentiation in thymus Biological process - NME2 4831 NME/NM23 nucleoside diphosphate kinase 2 peptidyl-histidine phosphorylation Biological process - BAD 572 BCL2-associated agonist of cell death positive regulation of mitochondrial membrane potential Biological process - IL4 3565 interleukin 4 protein binding Molecular function 10219247 NTN1 9423 netrin 1 protein binding Molecular function 10102268 FGF7 2252 fibroblast growth factor 7 positive regulation of epithelial cell proliferation involved in lung morphogenesis Biological process 9740653 TADA3 10474 transcriptional adaptor 3 mitotic nuclear division Biological process - PNMA3 29944 paraneoplastic Ma antigen 3 zinc ion binding Molecular function - DOK6 220164 docking protein 6 insulin receptor binding Molecular function - STK11 6794 serine/threonine kinase 11 regulation of Wnt signaling pathway Biological process - HS6ST1 9394 heparan sulfate 6-O-sulfotransferase 1 heparan sulfate 6-O-sulfotransferase activity Molecular function - ATP5D 513 ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit cellular metabolic process Biological process - TP53 7157 tumor protein p53 regulation of apoptotic process Biological process 14744935 CORO1A 11151 coronin, actin binding protein, 1A early endosome to recycling endosome transport Biological process - HIST1H4I 8294 histone cluster 1, H4i protein heterotetramerization Biological process 20498094 SERPINB13 5275 serpin peptidase inhibitor, clade B (ovalbumin), member 13 regulation of proteolysis Biological process 10512713 IFNGR1 3459 interferon gamma receptor 1 regulation of interferon-gamma-mediated signaling pathway Biological process - PPP1R11 6992 protein phosphatase 1, regulatory (inhibitor) subunit 11 protein binding Molecular function 9843442 PP2D1 151649 protein phosphatase 2C-like domain containing 1 metabolic process Biological process - CELF4 56853 CUGBP, Elav-like family member 4 positive regulation of mRNA splicing, via spliceosome Biological process 15009664 CHI3L1 1116 chitinase 3-like 1 (cartilage glycoprotein-39) extracellular matrix structural constituent Molecular function 8245017 ERMP1 79956 endoplasmic reticulum metallopeptidase 1 membrane Cellular component 19946888 CARD10 29775 caspase recruitment domain family, member 10 protein binding Molecular function 11259443 HIST1H4K 8362 histone cluster 1, H4k negative regulation of gene expression, epigenetic Biological process - EIF4A2 1974 eukaryotic translation initiation factor 4A2 cytosol Cellular component - TMEM39B 55116 transmembrane protein 39B integral component of membrane Cellular component - UBE2V2 7336 ubiquitin-conjugating enzyme E2 variant 2 negative regulation of neuron apoptotic process Biological process - RYR2 6262 ryanodine receptor 2 (cardiac) regulation of cardiac muscle contraction Biological process 11159936 SMAD5 4090 SMAD family member 5 transcription factor complex Cellular component - YAP1 10413 Yes-associated protein 1 positive regulation of transcription from RNA polymerase II promoter Biological process - PRSS3 5646 protease, serine, 3 cobalamin metabolic process Biological process - FGF10 2255 fibroblast growth factor 10 extracellular region Cellular component - PLB1 151056 phospholipase B1 phospholipid metabolic process Biological process - CD2 914 CD2 molecule external side of plasma membrane Cellular component 21460847 HDAC3 8841 histone deacetylase 3 circadian regulation of gene expression Biological process - G3BP1 10146 GTPase activating protein (SH3 domain) binding protein 1 cytoplasm Cellular component - MPO 4353 myeloperoxidase defense response Biological process 8621627 TF 7018 transferrin platelet activation Biological process - MRPL47 57129 mitochondrial ribosomal protein L47 structural constituent of ribosome Molecular function - NAPRT 93100 nicotinate phosphoribosyltransferase nicotinate nucleotide salvage Biological process - EGF 1950 epidermal growth factor innate immune response Biological process - IRF2BP1 26145 interferon regulatory factor 2 binding protein 1 protein binding Molecular function 18671972 CALM3 808 calmodulin 3 (phosphorylase kinase, delta) extracellular region Cellular component - VIP 7432 vasoactive intestinal peptide regulation of signal transduction Biological process - ZNF669 79862 zinc finger protein 669 transcription, DNA-templated Biological process - ZMYND15 84225 zinc finger, MYND-type containing 15 transcription, DNA-templated Biological process - NCF1C 654817 neutrophil cytosolic factor 1C pseudogene cytoplasm Cellular component - PRLHR 2834 prolactin releasing hormone receptor protein binding Molecular function 11641419 NONO 4841 non-POU domain containing, octamer-binding DNA repair Biological process - SEMA4G 57715 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G cell differentiation Biological process - NEFL 4747 neurofilament, light polypeptide axon transport of mitochondrion Biological process 15857389 AGTR1 185 angiotensin II receptor, type 1 angiotensin type II receptor activity Molecular function 15611106 TP63 8626 tumor protein p63 positive regulation of Notch signaling pathway Biological process 11641404 RBBP5 5929 retinoblastoma binding protein 5 methylated histone binding Molecular function 15960975 CETP 1071 cholesteryl ester transfer protein, plasma triglyceride binding Molecular function 2833496 EDIL3 10085 EGF-like repeats and discoidin I-like domains 3 positive regulation of cell-substrate adhesion Biological process - SMTNL1 219537 smoothelin-like 1 nucleus Cellular component - ERVK13-1 100507321 endogenous retrovirus group K13, member 1 structural molecule activity Molecular function - OR1L1 26737 olfactory receptor, family 1, subfamily L, member 1 G-protein coupled receptor signaling pathway Biological process - CLCN3 1182 chloride channel, voltage-sensitive 3 Golgi membrane Cellular component - FAM74A1 401507 family with sequence similarity 74, member A1 protein binding Molecular function 25416956 SCN1B 6324 sodium channel, voltage gated, type I beta subunit membrane depolarization during Purkinje myocyte cell action potential Biological process 18464934 ATP8B3 148229 ATPase, aminophospholipid transporter, class I, type 8B, member 3 ATP binding Molecular function - ANXA8 653145 annexin A8 actin filament binding Molecular function 16638567 RFFL 117584 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase negative regulation of tumor necrosis factor-mediated signaling pathway Biological process 18450452 FSHB 2488 follicle stimulating hormone, beta polypeptide positive regulation of cell migration Biological process 20613903 ANGPT1 284 angiopoietin 1 positive regulation of endothelial cell migration Biological process 12958144 SLC8A1 6546 solute carrier family 8 (sodium/calcium exchanger), member 1 cellular response to caffeine Biological process - IRS2 8660 insulin receptor substrate 2 brain development Biological process - KDM6B 23135 lysine (K)-specific demethylase 6B sequence-specific DNA binding Molecular function - CALM1 801 calmodulin 1 (phosphorylase kinase, delta) regulation of heart rate Biological process 23040497 MFN2 9927 mitofusin 2 mitochondrial membrane organization Biological process 11181170 ABCD4 5826 ATP-binding cassette, sub-family D (ALD), member 4 small molecule metabolic process Biological process - EPHB2 2048 EPH receptor B2 positive regulation of long-term neuronal synaptic plasticity Biological process - PDK2 5164 pyruvate dehydrogenase kinase, isozyme 2 ATP binding Molecular function 16401071 ESYT3 83850 extended synaptotagmin-like protein 3 lipid transport Biological process - RELA 5970 v-rel avian reticuloendotheliosis viral oncogene homolog A negative regulation of transcription from RNA polymerase II promoter Biological process 17350185 RFFL 117584 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase proteasome-mediated ubiquitin-dependent protein catabolic process Biological process 18382127 TFF1 7031 trefoil factor 1 growth factor activity Molecular function - NOTCH4 4855 notch 4 cell differentiation Biological process 11823422 OIP5 11339 Opa interacting protein 5 mitotic nuclear division Biological process - HRK 8739 harakiri, BCL2 interacting protein protein binding Molecular function 14596824 WFDC12 128488 WAP four-disulfide core domain 12 extracellular region Cellular component - CYP11B1 1584 cytochrome P450, family 11, subfamily B, polypeptide 1 sterol metabolic process Biological process - CTNNBIP1 56998 catenin, beta interacting protein 1 negative regulation of smooth muscle cell proliferation Biological process - ATP5I 521 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E mitochondrion Cellular component - CARD16 114769 caspase recruitment domain family, member 16 cysteine-type endopeptidase inhibitor activity Molecular function - PSMF1 9491 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) negative regulation of canonical Wnt signaling pathway Biological process - COBL 23242 cordon-bleu WH2 repeat protein axon Cellular component - IFNGR1 3459 interferon gamma receptor 1 postsynaptic density Cellular component - UBR3 130507 ubiquitin protein ligase E3 component n-recognin 3 (putative) olfactory behavior Biological process - MLXIPL 51085 MLX interacting protein-like negative regulation of transcription, DNA-templated Biological process 11230181 TRAK2 66008 trafficking protein, kinesin binding 2 cytoplasm Cellular component - PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 dendrite development Biological process - KLB 152831 klotho beta innate immune response Biological process - TCL1A 8115 T-cell leukemia/lymphoma 1A pronucleus Cellular component - SUV39H1 6839 suppressor of variegation 3-9 homolog 1 (Drosophila) histone H3-K9 dimethylation Biological process - OXT 5020 oxytocin/neurophysin I prepropeptide response to glucocorticoid Biological process - KMO 8564 kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) response to salt stress Biological process 10672018 RNF144B 255488 ring finger protein 144B ligase activity Molecular function - ACOT7 11332 acyl-CoA thioesterase 7 nucleoplasm Cellular component - HOXC13 3229 homeobox C13 positive regulation of transcription from RNA polymerase II promoter Biological process - GPR27 2850 G protein-coupled receptor 27 plasma membrane Cellular component - AP1AR 55435 adaptor-related protein complex 1 associated regulatory protein late endosome Cellular component - AQP10 89872 aquaporin 10 glycerol channel activity Molecular function - MAGEC2 51438 melanoma antigen family C2 positive regulation of ubiquitin-protein transferase activity Biological process 20864041 TCFL5 10732 transcription factor-like 5 (basic helix-loop-helix) multicellular organismal development Biological process - BCO2 83875 beta-carotene oxygenase 2 metal ion binding Molecular function - GSTP1 2950 glutathione S-transferase pi 1 kinase regulator activity Molecular function - EXOSC7 23016 exosome component 7 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Biological process - AFTPH 54812 aftiphilin cytosol Cellular component 15758025 INO80E 283899 INO80 complex subunit E nucleolus Cellular component - UBB 7314 ubiquitin B antigen processing and presentation of exogenous peptide antigen via MHC class I Biological process - FGD3 89846 FYVE, RhoGEF and PH domain containing 3 actin cytoskeleton organization Biological process - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa positive regulation of epithelial cell proliferation involved in prostate gland development Biological process - LASP1 3927 LIM and SH3 protein 1 extracellular exosome Cellular component 23376485 CDK4 1019 cyclin-dependent kinase 4 perinuclear region of cytoplasm Cellular component - HNF1B 6928 HNF1 homeobox B hindbrain development Biological process - COX5A 9377 cytochrome c oxidase subunit Va mitochondrial inner membrane Cellular component - PEPD 5184 peptidase D aminopeptidase activity Molecular function - CDK5RAP1 51654 CDK5 regulatory subunit associated protein 1 negative regulation of cyclin-dependent protein serine/threonine kinase activity Biological process 11882646 ZNF365 22891 zinc finger protein 365 cytoplasm Cellular component - LUM 4060 lumican protein binding Molecular function 25304424 APOC1 341 apolipoprotein C-I fatty acid binding Molecular function 17339654 SLC9A3R1 9368 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 PDZ domain binding Molecular function 16236806 EPHX1 2052 epoxide hydrolase 1, microsomal (xenobiotic) cis-stilbene-oxide hydrolase activity Molecular function - SOD2 6648 superoxide dismutase 2, mitochondrial manganese ion binding Molecular function 10511315 PXYLP1 92370 2-phosphoxylose phosphatase 1 positive regulation of heparan sulfate proteoglycan biosynthetic process Biological process 24425863 LMTK3 114783 lemur tyrosine kinase 3 molecular_function Molecular function - IGHA2 3494 immunoglobulin heavy constant alpha 2 (A2m marker) immune response Biological process 2241915 NLGN1 22871 neuroligin 1 N-methyl-D-aspartate selective glutamate receptor complex Cellular component - MAP3K13 9175 mitogen-activated protein kinase kinase kinase 13 metal ion binding Molecular function - SPHK1 8877 sphingosine kinase 1 positive regulation of protein ubiquitination Biological process 20577214 BAD 572 BCL2-associated agonist of cell death response to drug Biological process - PHF21A 51317 PHD finger protein 21A nucleoplasm Cellular component - ALPK2 115701 alpha-kinase 2 protein serine/threonine kinase activity Molecular function - CTSH 1512 cathepsin H cytosol Cellular component 9050938 GNL3 26354 guanine nucleotide binding protein-like 3 (nucleolar) nucleolus Cellular component - SLC16A5 9121 solute carrier family 16 (monocarboxylate transporter), member 5 lactate transmembrane transporter activity Molecular function - MOB4 25843 MOB family member 4, phocein metal ion binding Molecular function - PHKG1 5260 phosphorylase kinase, gamma 1 (muscle) phosphorylase kinase activity Molecular function - SMS 6611 spermine synthase spermine biosynthetic process Biological process - PAK6 56924 p21 protein (Cdc42/Rac)-activated kinase 6 protein binding Molecular function 24510904 RPL14 9045 ribosomal protein L14 viral transcription Biological process - BRCA2 675 breast cancer 2, early onset centrosome Cellular component 17286961 AP4M1 9179 adaptor-related protein complex 4, mu 1 subunit transporter activity Molecular function 10066790 DUS2 54920 dihydrouridine synthase 2 flavin adenine dinucleotide binding Molecular function - CCBL2 56267 cysteine conjugate-beta lyase 2 pyridoxal phosphate binding Molecular function - MED30 90390 mediator complex subunit 30 intracellular steroid hormone receptor signaling pathway Biological process 11867769 LOC440786 440786 uncharacterized LOC440786 Fc-gamma receptor signaling pathway involved in phagocytosis Biological process - TUSC2 11334 tumor suppressor candidate 2 positive regulation of interleukin-10 production Biological process - FECH 2235 ferrochelatase response to methylmercury Biological process - RFC5 5985 replication factor C (activator 1) 5, 36.5kDa DNA repair Biological process - TMPRSS15 5651 transmembrane protease, serine 15 serine-type endopeptidase activity Molecular function - AXIN1 8312 axin 1 positive regulation of peptidyl-serine phosphorylation Biological process 18593713 VPS37D 155382 vacuolar protein sorting 37 homolog D (S. cerevisiae) intracellular transport of virus Biological process - ACTN4 81 actinin, alpha 4 ligand-dependent nuclear receptor transcription coactivator activity Molecular function 22351778 HOXC9 3225 homeobox C9 embryonic skeletal system morphogenesis Biological process - CAP2 10486 CAP, adenylate cyclase-associated protein, 2 (yeast) signal transduction Biological process 7962207 KCTD19 146212 potassium channel tetramerization domain containing 19 protein homooligomerization Biological process - CENPC 1060 centromere protein C nucleus Cellular component - MCU 90550 mitochondrial calcium uniporter uniplex complex Cellular component 22925203 PPP5C 5536 protein phosphatase 5, catalytic subunit protein serine/threonine phosphatase activity Molecular function 7925273 TMEM178B 100507421 transmembrane protein 178B integral component of membrane Cellular component - KIF3C 3797 kinesin family member 3C antigen processing and presentation of exogenous peptide antigen via MHC class II Biological process - TBC1D7 51256 TBC1 domain family, member 7 negative regulation of cilium assembly Biological process 17646400 PSG7 5676 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) female pregnancy Biological process 1690992 EPB42 2038 erythrocyte membrane protein band 4.2 protein binding Molecular function 12646258 DOLPP1 57171 dolichyldiphosphatase 1 protein N-linked glycosylation via asparagine Biological process - MALL 7851 mal, T-cell differentiation protein-like cholesterol homeostasis Biological process 11294831 KAT6B 23522 K(lysine) acetyltransferase 6B negative regulation of transcription, DNA-templated Biological process 10497217 SPINT2 10653 serine peptidase inhibitor, Kunitz type, 2 cytoplasm Cellular component 11606055 TEK 7010 TEK tyrosine kinase, endothelial angiogenesis Biological process - OR8H3 390152 olfactory receptor, family 8, subfamily H, member 3 G-protein coupled receptor signaling pathway Biological process - LRAT 9227 lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) rough endoplasmic reticulum Cellular component - POLR2D 5433 polymerase (RNA) II (DNA directed) polypeptide D nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay Biological process - DDN 23109 dendrin perikaryon Cellular component - LSG1 55341 large 60S subunit nuclear export GTPase 1 GTP binding Molecular function 16209721 ITGA8 8516 integrin, alpha 8 extracellular matrix organization Biological process - INSRR 3645 insulin receptor-related receptor protein autophosphorylation Biological process 21641549 HIST2H4B 554313 histone cluster 2, H4b DNA replication-independent nucleosome assembly Biological process 14718166 OR6C70 390327 olfactory receptor, family 6, subfamily C, member 70 detection of chemical stimulus involved in sensory perception of smell Biological process - HLA-B 3106 major histocompatibility complex, class I, B receptor binding Molecular function 20008523 SPEG 10290 SPEG complex locus protein phosphorylation Biological process - IL1R1 3554 interleukin 1 receptor, type I protein binding Molecular function 12925853 AEBP1 165 AE binding protein 1 proteolysis Biological process - CTNNBL1 56259 catenin, beta like 1 spliceosomal complex Cellular component 20176811 ALDOA 226 aldolase A, fructose-bisphosphate small molecule metabolic process Biological process - RAB39A 54734 RAB39A, member RAS oncogene family phagocytic vesicle Cellular component 21255211 OR4F17 81099 olfactory receptor, family 4, subfamily F, member 17 plasma membrane Cellular component - HSD17B2 3294 hydroxysteroid (17-beta) dehydrogenase 2 placenta development Biological process - ABCB9 23457 ATP-binding cassette, sub-family B (MDR/TAP), member 9 peptide transport Biological process 17977821 TP53INP1 94241 tumor protein p53 inducible nuclear protein 1 nucleus Cellular component 22470510 ITGA2B 3674 integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) integral component of plasma membrane Cellular component 2439501 ETV5 2119 ets variant 5 neuromuscular synaptic transmission Biological process - CASP7 840 caspase 7, apoptosis-related cysteine peptidase execution phase of apoptosis Biological process - SLC44A1 23446 solute carrier family 44 (choline transporter), member 1 glycerophospholipid biosynthetic process Biological process - SPPL2B 56928 signal peptide peptidase like 2B regulation of immune response Biological process 16829952 LRP8 7804 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor very-low-density lipoprotein particle receptor activity Molecular function 8626535 EMILIN3 90187 elastin microfibril interfacer 3 cytoplasm Cellular component - KCNH1 3756 potassium channel, voltage gated eag related subfamily H, member 1 regulation of ion transmembrane transport Biological process - GPD1L 23171 glycerol-3-phosphate dehydrogenase 1-like ion channel binding Molecular function 19666841 GRPR 2925 gastrin-releasing peptide receptor cell proliferation Biological process 1655761 TMX4 56255 thioredoxin-related transmembrane protein 4 oxidation-reduction process Biological process - YWHAG 7532 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma G2/M transition of mitotic cell cycle Biological process - TRAF2 7186 TNF receptor-associated factor 2 cytosol Cellular component - PRCP 5547 prolylcarboxypeptidase (angiotensinase C) regulation of thyroid hormone mediated signaling pathway Biological process - GFPT1 2673 glutamine--fructose-6-phosphate transaminase 1 cytosol Cellular component - SNPH 9751 syntaphilin cytoplasm Cellular component 15459722 GRIN1 2902 glutamate receptor, ionotropic, N-methyl D-aspartate 1 glycine binding Molecular function 17047094 KCNG2 26251 potassium channel, voltage gated modifier subfamily G, member 2 protein homooligomerization Biological process - ASXL3 80816 additional sex combs like transcriptional regulator 3 regulation of transcription, DNA-templated Biological process - TSHZ3 57616 teashirt zinc finger homeobox 3 kidney morphogenesis Biological process - C1QL1 10882 complement component 1, q subcomponent-like 1 extracellular region Cellular component - MAPK13 5603 mitogen-activated protein kinase 13 protein serine/threonine kinase activity Molecular function 12244047 PI4KA 5297 phosphatidylinositol 4-kinase, catalytic, alpha cytoplasm Cellular component - MYCBP 26292 MYC binding protein mitochondrion Cellular component - TEAD4 7004 TEA domain family member 4 sequence-specific DNA binding transcription factor activity Molecular function 18579750 PIK3CB 5291 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta regulation of cell-matrix adhesion Biological process 25139353 FCGR1B 2210 Fc fragment of IgG, high affinity Ib, receptor (CD64) immunoglobulin receptor activity Molecular function 1430234 NPHS1 4868 nephrosis 1, congenital, Finnish type (nephrin) glomerular visceral epithelial cell development Biological process 17464107 VPS25 84313 vacuolar protein sorting 25 homolog (S. cerevisiae) structural molecule activity Molecular function - GABPB1 2553 GA binding protein transcription factor, beta subunit 1 transcription, DNA-templated Biological process - CLCA1 1179 chloride channel accessory 1 calcium ion transport Biological process - TSSK3 81629 testis-specific serine kinase 3 spermatogenesis Biological process - ATF4 468 activating transcription factor 4 positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance Biological process 14685163 SOS1 6654 son of sevenless homolog 1 (Drosophila) blood coagulation Biological process - FAM169A 26049 family with sequence similarity 169, member A nuclear inner membrane Cellular component - IFT88 8100 intraflagellar transport 88 response to fluid shear stress Biological process - GOLPH3 64083 golgi phosphoprotein 3 (coat-protein) protein secretion Biological process 23500462 TNXB 7148 tenascin XB proteinaceous extracellular matrix Cellular component 7686164 VEGFA 7422 vascular endothelial growth factor A regulation of cGMP metabolic process Biological process 16150726 PSME3 10197 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) apoptotic process Biological process - KCNJ8 3764 potassium channel, inwardly rectifying subfamily J, member 8 inward rectifier potassium channel activity Molecular function 7890693 MAPK11 5600 mitogen-activated protein kinase 11 transcription, DNA-templated Biological process - RBM14 10432 RNA binding motif protein 14 nucleotide binding Molecular function - AGT 183 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) positive regulation of nitric oxide biosynthetic process Biological process - PTOV1 53635 prostate tumor overexpressed 1 plasma membrane Cellular component - DDX17 10521 DEAD (Asp-Glu-Ala-Asp) box helicase 17 nucleoplasm Cellular component - HJURP 55355 Holliday junction recognition protein condensed chromosome kinetochore Cellular component 19410545 OR8K5 219453 olfactory receptor, family 8, subfamily K, member 5 G-protein coupled receptor signaling pathway Biological process - SGSM3 27352 small G protein signaling modulator 3 cytosol Cellular component 17562788 TNFRSF11B 4982 tumor necrosis factor receptor superfamily, member 11b signal transduction Biological process - ZBTB49 166793 zinc finger and BTB domain containing 49 metal ion binding Molecular function - HIATL1 84641 hippocampus abundant transcript-like 1 transmembrane transport Biological process - WNT4 54361 wingless-type MMTV integration site family, member 4 liver development Biological process 15312687 TLX3 30012 T-cell leukemia homeobox 3 regulation of respiratory gaseous exchange by neurological system process Biological process - CLCF1 23529 cardiotrophin-like cytokine factor 1 growth factor activity Molecular function 14632778 STK38 11329 serine/threonine kinase 38 protein phosphorylation Biological process 12493777 WAPAL 23063 wings apart-like homolog (Drosophila) cytosol Cellular component - ECE1 1889 endothelin converting enzyme 1 ear development Biological process 9915973 LCOR 84458 ligand dependent nuclear receptor corepressor nucleus Cellular component - METTL21EP 121952 methyltransferase like 21E, pseudogene methyltransferase activity Molecular function - NRXN1 9378 neurexin 1 metal ion binding Molecular function - AGPAT3 56894 1-acylglycerol-3-phosphate O-acyltransferase 3 small molecule metabolic process Biological process - ANXA1 301 annexin A1 alpha-beta T cell differentiation Biological process - ANKFY1 51479 ankyrin repeat and FYVE domain containing 1 lysosomal membrane Cellular component 17897319 B4GALT7 11285 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 extracellular matrix Cellular component 16583246 UMODL1 89766 uromodulin-like 1 calcium ion binding Molecular function - ERBB2 2064 erb-b2 receptor tyrosine kinase 2 heart development Biological process - MZT1 440145 mitotic spindle organizing protein 1 gamma-tubulin ring complex Cellular component 20360068 MBD3 53615 methyl-CpG binding domain protein 3 methylation-dependent chromatin silencing Biological process - MMP24 10893 matrix metallopeptidase 24 (membrane-inserted) proteolysis Biological process - POLD1 5424 polymerase (DNA directed), delta 1, catalytic subunit cytoplasm Cellular component - TRUB1 142940 TruB pseudouridine (psi) synthase family member 1 pseudouridine synthase activity Molecular function - NCK1 4690 NCK adaptor protein 1 protein binding, bridging Molecular function 16835242 OR10J4 391121 olfactory receptor, family 10, subfamily J, member 4 (gene/pseudogene) olfactory receptor activity Molecular function - CXCL8 3576 chemokine (C-X-C motif) ligand 8 immune response Biological process - ATXN1 6310 ataxin 1 chromatin binding Molecular function - NOX4 50507 NADPH oxidase 4 positive regulation of ERK1 and ERK2 cascade Biological process - EHD3 30845 EH-domain containing 3 ATP binding Molecular function - RPS6KA5 9252 ribosomal protein S6 kinase, 90kDa, polypeptide 5 positive regulation of histone phosphorylation Biological process 20018936 MMAB 326625 methylmalonic aciduria (cobalamin deficiency) cblB type cobalamin biosynthetic process Biological process - PLEKHG5 57449 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 positive regulation of apoptotic process Biological process - DEF8 54849 differentially expressed in FDCP 8 homolog (mouse) zinc ion binding Molecular function - CD58 965 CD58 molecule positive regulation of interleukin-8 secretion Biological process 19109405 HLA-DRB3 3125 major histocompatibility complex, class II, DR beta 3 late endosome membrane Cellular component 18305173 ETV7 51513 ets variant 7 protein binding Molecular function 12588862 DCHS1 8642 dachsous cadherin-related 1 branching involved in ureteric bud morphogenesis Biological process - RAB35 11021 RAB35, member RAS oncogene family GTPase activity Molecular function 17562788 ARAF 369 A-Raf proto-oncogene, serine/threonine kinase positive regulation of peptidyl-serine phosphorylation Biological process 19667065 ATL1 51062 atlastin GTPase 1 Golgi apparatus Cellular component - CLEC4D 338339 C-type lectin domain family 4, member D plasma membrane Cellular component - TCF3 6929 transcription factor 3 positive regulation of cell cycle Biological process 11509675 KCNK5 8645 potassium channel, two pore domain subfamily K, member 5 integral component of plasma membrane Cellular component 9812978 TPR 7175 translocated promoter region, nuclear basket protein mitotic spindle Cellular component 20133940 SLC17A7 57030 solute carrier family 17 (vesicular glutamate transporter), member 7 presynaptic active zone Cellular component - SNX6 58533 sorting nexin 6 cytoplasmic membrane-bounded vesicle Cellular component - RP1 6101 retinitis pigmentosa 1 (autosomal dominant) axoneme assembly Biological process - NPPA 4878 natriuretic peptide A negative regulation of systemic arterial blood pressure Biological process - FUZ 80199 fuzzy planar cell polarity protein cytoplasm Cellular component - CDRT15P2 644694 CMT1A duplicated region transcript 15 pseudogene 2 integral component of membrane Cellular component - ANG 283 angiogenin, ribonuclease, RNase A family, 5 receptor binding Molecular function 9122172 CSNK2B 1460 casein kinase 2, beta polypeptide PcG protein complex Cellular component 21282530 DPH2 1802 DPH2 homolog (S. cerevisiae) cytosol Cellular component - SLC26A3 1811 solute carrier family 26 (anion exchanger), member 3 sulfate transmembrane transport Biological process - STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced nucleoplasm Cellular component - AFP 174 alpha-fetoprotein progesterone metabolic process Biological process - CLIC1 1192 chloride intracellular channel 1 brush border Cellular component 10793131 KIAA1429 25962 KIAA1429 MIS complex Cellular component 24981863 IFNA4 3441 interferon, alpha 4 response to virus Biological process 3891272 PDK2 5164 pyruvate dehydrogenase kinase, isozyme 2 insulin receptor signaling pathway Biological process - CCM2 83605 cerebral cavernous malformation 2 venous blood vessel morphogenesis Biological process - HAL 3034 histidine ammonia-lyase histidine ammonia-lyase activity Molecular function - DNAJA3 9093 DnaJ (Hsp40) homolog, subfamily A, member 3 NF-kappaB binding Molecular function 15601829 BECN1 8678 beclin 1, autophagy related phagocytic vesicle Cellular component - FLNC 2318 filamin C, gamma muscle fiber development Biological process - NGDN 25983 neuroguidin, EIF4E binding protein dendrite Cellular component - OTC 5009 ornithine carbamoyltransferase ornithine carbamoyltransferase activity Molecular function 2556444 GDF10 2662 growth differentiation factor 10 cytokine activity Molecular function - CLCA2 9635 chloride channel accessory 2 extracellular region Cellular component - BDH2 56898 3-hydroxybutyrate dehydrogenase, type 2 fatty acid beta-oxidation Biological process 16380372 ARL3 403 ADP-ribosylation factor-like 3 metabolic process Biological process - CDC42 998 cell division cycle 42 blood coagulation Biological process - STARD8 9754 StAR-related lipid transfer (START) domain containing 8 small GTPase mediated signal transduction Biological process - KIF4B 285643 kinesin family member 4B blood coagulation Biological process - ATP9B 374868 ATPase, class II, type 9B metabolic process Biological process - UGDH 7358 UDP-glucose 6-dehydrogenase electron carrier activity Molecular function 9737970 KIF18B 146909 kinesin family member 18B kinesin binding Molecular function 21820309 NRG1 3084 neuregulin 1 axon Cellular component - HIRA 7290 histone cell cycle regulator chromatin modification Biological process - SEMA3A 10371 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A axonogenesis involved in innervation Biological process - ZNF770 54989 zinc finger protein 770 transcription from RNA polymerase II promoter Biological process - RPL13 6137 ribosomal protein L13 cellular protein metabolic process Biological process - PSMA7 5688 proteasome (prosome, macropain) subunit, alpha type, 7 gene expression Biological process - EFEMP2 30008 EGF containing fibulin-like extracellular matrix protein 2 extracellular vesicle Cellular component 24769233 PLA2G4B 100137049 phospholipase A2, group IVB (cytosolic) early endosome membrane Cellular component - VAV3 10451 vav 3 guanine nucleotide exchange factor apoptotic signaling pathway Biological process - NUMB 8650 numb homolog (Drosophila) Notch signaling pathway Biological process - STX3 6809 syntaxin 3 long-term synaptic potentiation Biological process - CEACAM1 634 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) leukocyte migration Biological process - RUFY1 80230 RUN and FYVE domain containing 1 zinc ion binding Molecular function - RABL2B 11158 RAB, member of RAS oncogene family-like 2B GTPase activity Molecular function 10444334 RELA 5970 v-rel avian reticuloendotheliosis viral oncogene homolog A protein complex binding Molecular function - PDPN 10630 podoplanin folic acid transport Biological process - ISCA2 122961 iron-sulfur cluster assembly 2 metal ion binding Molecular function - S1PR2 9294 sphingosine-1-phosphate receptor 2 lipid binding Molecular function 10617617 MED1 5469 mediator complex subunit 1 ERK1 and ERK2 cascade Biological process 18391015 DCX 1641 doublecortin nervous system development Biological process 9489699 BMP7 655 bone morphogenetic protein 7 epithelial to mesenchymal transition Biological process 14679171 NEK5 341676 NIMA-related kinase 5 positive regulation of striated muscle cell differentiation Biological process - RALGAPA2 57186 Ral GTPase activating protein, alpha subunit 2 (catalytic) activation of GTPase activity Biological process - DAZ1 1617 deleted in azoospermia 1 spermatogenesis Biological process - ATP7A 538 ATPase, Cu++ transporting, alpha polypeptide epinephrine metabolic process Biological process - LSM1 27257 LSM1, U6 small nuclear RNA associated nucleus Cellular component 18559850 NEUROG2 63973 neurogenin 2 positive regulation of transcription from RNA polymerase II promoter Biological process - MAP3K3 4215 mitogen-activated protein kinase kinase kinase 3 positive regulation of p38MAPK cascade Biological process - TMEM52B 120939 transmembrane protein 52B molecular_function Molecular function - POLD2 5425 polymerase (DNA directed), delta 2, accessory subunit transcription-coupled nucleotide-excision repair Biological process - SIX1 6495 SIX homeobox 1 regulation of epithelial cell proliferation Biological process - DNAJC24 120526 DnaJ (Hsp40) homolog, subfamily C, member 24 positive regulation of ATPase activity Biological process 22367199 AURKA 6790 aurora kinase A mitotic spindle organization Biological process - CEBPG 1054 CCAAT/enhancer binding protein (C/EBP), gamma double-stranded DNA binding Molecular function - ARR3 407 arrestin 3, retinal (X-arrestin) regulation of protein phosphorylation Biological process - APOA2 336 apolipoprotein A-II cholesterol homeostasis Biological process 14967812 RECQL5 9400 RecQ protein-like 5 DNA recombination Biological process - FOXN4 121643 forkhead box N4 transcription, DNA-templated Biological process - E2F1 1869 E2F transcription factor 1 negative regulation of DNA binding Biological process 20176812 LOXL2 4017 lysyl oxidase-like 2 receptor-mediated endocytosis Biological process - SLC16A12 387700 solute carrier family 16, member 12 lactate transmembrane transporter activity Molecular function - RBMX 27316 RNA binding motif protein, X-linked extracellular exosome Cellular component 18445477 KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog protease binding Molecular function - SOX9 6662 SRY (sex determining region Y)-box 9 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 20484372 FGF10 2255 fibroblast growth factor 10 keratinocyte proliferation Biological process - RNF7 9616 ring finger protein 7 nucleus Cellular component 10082581 KMT2D 8085 lysine (K)-specific methyltransferase 2D protein binding Molecular function 12482968 CXCL13 10563 chemokine (C-X-C motif) ligand 13 positive regulation of integrin activation Biological process - COL13A1 1305 collagen, type XIII, alpha 1 extracellular matrix disassembly Biological process - SLC44A3 126969 solute carrier family 44, member 3 small molecule metabolic process Biological process - HPSE2 60495 heparanase 2 (inactive) proteinaceous extracellular matrix Cellular component 20576607 PLK2 10769 polo-like kinase 2 mitotic spindle organization Biological process 19001868 BIRC8 112401 baculoviral IAP repeat containing 8 protease binding Molecular function - DUSP4 1846 dual specificity phosphatase 4 MAP kinase tyrosine/serine/threonine phosphatase activity Molecular function - HYAL1 3373 hyaluronoglucosaminidase 1 virus receptor activity Molecular function 11296287 ELOVL3 83401 ELOVL fatty acid elongase 3 fatty acid elongation, polyunsaturated fatty acid Biological process 20937905 TAF5 6877 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa transcription initiation from RNA polymerase II promoter Biological process - ABCA7 10347 ATP-binding cassette, sub-family A (ABC1), member 7 negative regulation of beta-amyloid formation Biological process - PHYH 5264 phytanoyl-CoA 2-hydroxylase peroxisome Cellular component 9326939 CRTC3 64784 CREB regulated transcription coactivator 3 viral process Biological process - HDAC2 3066 histone deacetylase 2 regulation of protein kinase B signaling Biological process - ABHD14B 84836 abhydrolase domain containing 14B positive regulation of transcription from RNA polymerase II promoter Biological process 14672934 RYR2 6262 ryanodine receptor 2 (cardiac) extracellular exosome Cellular component 23376485 CPQ 10404 carboxypeptidase Q lysosome Cellular component - LOXL2 4017 lysyl oxidase-like 2 scavenger receptor activity Molecular function - ZNF302 55900 zinc finger protein 302 transcription, DNA-templated Biological process - FGFR4 2264 fibroblast growth factor receptor 4 endosome Cellular component - TAB3 257397 TGF-beta activated kinase 1/MAP3K7 binding protein 3 JNK cascade Biological process - NYX 60506 nyctalopin biological_process Biological process - TOMM22 56993 translocase of outer mitochondrial membrane 22 homolog (yeast) mitochondrial outer membrane translocase complex Cellular component 12198123 GABRB2 2561 gamma-aminobutyric acid (GABA) A receptor, beta 2 inner ear receptor cell development Biological process - DDX50 79009 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 poly(A) RNA binding Molecular function 22658674 NTRK3 4916 neurotrophic tyrosine kinase, receptor, type 3 negative regulation of protein phosphorylation Biological process 23027130 NXPE2 120406 neurexophilin and PC-esterase domain family, member 2 integral component of membrane Cellular component - MRAP2 112609 melanocortin 2 receptor accessory protein 2 identical protein binding Molecular function 19329486 ADGRA2 25960 adhesion G protein-coupled receptor A2 G-protein coupled receptor signaling pathway Biological process - NPNT 255743 nephronectin proteinaceous extracellular matrix Cellular component - KCNK3 3777 potassium channel, two pore domain subfamily K, member 3 regulation of ion transmembrane transport Biological process - CH25H 9023 cholesterol 25-hydroxylase lipid metabolic process Biological process 9852097 HTR2B 3357 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled plasma membrane Cellular component - SAFB2 9667 scaffold attachment factor B2 nucleoplasm Cellular component - REC114 283677 REC114 meiotic recombination protein meiotic cell cycle Biological process - KCNJ2 3759 potassium channel, inwardly rectifying subfamily J, member 2 regulation of membrane repolarization Biological process 11371347 KHK 3795 ketohexokinase (fructokinase) small molecule metabolic process Biological process - NUP107 57122 nucleoporin 107kDa transmembrane transport Biological process - AXL 558 AXL receptor tyrosine kinase negative regulation of neuron apoptotic process Biological process - FOXP2 93986 forkhead box P2 RNA polymerase II core promoter proximal region sequence-specific DNA binding Molecular function - TP53 7157 tumor protein p53 double-stranded DNA binding Molecular function - SERPINB13 5275 serpin peptidase inhibitor, clade B (ovalbumin), member 13 response to UV Biological process 9297979 MBTPS1 8720 membrane-bound transcription factor peptidase, site 1 regulation of transcription factor import into nucleus Biological process - HDAC2 3066 histone deacetylase 2 protein complex Cellular component 16217013 SEC23A 10484 Sec23 homolog A (S. cerevisiae) protein binding Molecular function 10075675 SLC25A38 54977 solute carrier family 25, member 38 integral component of membrane Cellular component - MAP1S 55201 microtubule-associated protein 1S actin filament binding Molecular function 12762840 TFAP4 7023 transcription factor AP-4 (activating enhancer binding protein 4) negative regulation of transcription, DNA-templated Biological process 18818310 ST8SIA4 7903 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 protein glycosylation Biological process 10766765 KLF9 687 Kruppel-like factor 9 regulation of transcription from RNA polymerase II promoter Biological process 1356762 PIP4K2B 8396 phosphatidylinositol-5-phosphate 4-kinase, type II, beta phosphatidylinositol biosynthetic process Biological process - ADCY2 108 adenylate cyclase 2 (brain) adenylate cyclase-modulating G-protein coupled receptor signaling pathway Biological process - NEURL3 93082 neuralized E3 ubiquitin protein ligase 3 ubiquitin-protein transferase activity Molecular function - CPEB1 64506 cytoplasmic polyadenylation element binding protein 1 translation repressor activity, nucleic acid binding Molecular function - NKX2-1 7080 NK2 homeobox 1 forebrain development Biological process 15494458 VAV1 7409 vav 1 guanine nucleotide exchange factor reactive oxygen species metabolic process Biological process - ADAT2 134637 adenosine deaminase, tRNA-specific 2 protein binding Molecular function 25416956 TAOK3 51347 TAO kinase 3 ATP binding Molecular function - HOXB7 3217 homeobox B7 protein binding Molecular function 17308091 PLIN5 440503 perilipin 5 positive regulation of sequestering of triglyceride Biological process - DNAJC1 64215 DnaJ (Hsp40) homolog, subfamily C, member 1 positive regulation of ATPase activity Biological process 14668352 B4GALT1 2683 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 extracellular matrix organization Biological process - SMAD6 4091 SMAD family member 6 ubiquitin protein ligase binding Molecular function 11278251 DAG1 1605 dystroglycan 1 (dystrophin-associated glycoprotein 1) calcium-dependent cell-matrix adhesion Biological process - NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 1406630 EVX2 344191 even-skipped homeobox 2 biological_process Biological process - FMNL1 752 formin-like 1 profilin binding Molecular function - MLXIPL 51085 MLX interacting protein-like positive regulation of transcription, DNA-templated Biological process 11230181 SNX14 57231 sorting nexin 14 integral component of membrane Cellular component - PSKH1 5681 protein serine kinase H1 microtubule organizing center Cellular component - AMER1 139285 APC membrane recruitment protein 1 Wnt signaling pathway Biological process - CRYZL1 9946 crystallin, zeta (quinone reductase)-like 1 oxidation-reduction process Biological process - UQCRFS1 7386 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 2 iron, 2 sulfur cluster binding Molecular function - NUP37 79023 nucleoporin 37kDa mitotic cell cycle Biological process - ENPEP 2028 glutamyl aminopeptidase (aminopeptidase A) brush border Cellular component - TAAR2 9287 trace amine associated receptor 2 sensory perception of chemical stimulus Biological process - SDC1 6382 syndecan 1 myoblast development Biological process - CYBA 1535 cytochrome b-245, alpha polypeptide superoxide-generating NADPH oxidase activity Molecular function 1763037 PGF 5228 placental growth factor response to hypoxia Biological process - CSN3 1448 casein kappa molecular_function Molecular function - PPAT 5471 phosphoribosyl pyrophosphate amidotransferase metal ion binding Molecular function - FKBP1A 2280 FK506 binding protein 1A, 12kDa peptidyl-prolyl cis-trans isomerase activity Molecular function 11322937 HLX 3142 H2.0-like homeobox negative regulation of T-helper 2 cell differentiation Biological process - FERMT3 83706 fermitin family member 3 membrane Cellular component 19946888 SCAMP2 10066 secretory carrier membrane protein 2 Golgi apparatus Cellular component - LOXL2 4017 lysyl oxidase-like 2 chromatin binding Molecular function 22483618 TIGIT 201633 T cell immunoreceptor with Ig and ITIM domains positive regulation of interleukin-10 production Biological process 19011627 PIH1D3 139212 PIH1 domain containing 3 chaperone binding Molecular function - NTRK1 4914 neurotrophic tyrosine kinase, receptor, type 1 receptor complex Cellular component 23382219 PCDHA11 56138 protocadherin alpha 11 nervous system development Biological process 10380929 LRP1 4035 low density lipoprotein receptor-related protein 1 coated pit Cellular component - TFDP2 7029 transcription factor Dp-2 (E2F dimerization partner 2) protein binding Molecular function 16189514 FGD6 55785 FYVE, RhoGEF and PH domain containing 6 regulation of GTPase activity Biological process - BOP1 23246 block of proliferation 1 ribosome biogenesis Biological process 16043514 RICTOR 253260 RPTOR independent companion of MTOR, complex 2 phosphatidylinositol-mediated signaling Biological process - FTMT 94033 ferritin mitochondrial ferroxidase activity Molecular function - COL18A1 80781 collagen, type XVIII, alpha 1 structural molecule activity Molecular function - NDUFS4 4724 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) positive regulation of fibroblast proliferation Biological process 16478720 RAPGEF6 51735 Rap guanine nucleotide exchange factor (GEF) 6 plasma membrane Cellular component 11524421 SHPRH 257218 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase ubiquitin-protein transferase activity Molecular function 17108083 BAX 581 BCL2-associated X protein homeostasis of number of cells within a tissue Biological process - ARPC4 10093 actin related protein 2/3 complex, subunit 4, 20kDa extracellular exosome Cellular component 19056867 MYD88 4615 myeloid differentiation primary response 88 cytosol Cellular component - SLC25A10 1468 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 integral component of membrane Cellular component - CDC42 998 cell division cycle 42 Fc-gamma receptor signaling pathway involved in phagocytosis Biological process - PRKCD 5580 protein kinase C, delta programmed cell death Biological process - AMD1 262 adenosylmethionine decarboxylase 1 cytosol Cellular component - MLLT1 4298 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 regulation of transcription, DNA-templated Biological process - TMEM56 148534 transmembrane protein 56 cellular_component Cellular component - CYS1 192668 cystin 1 membrane raft Cellular component - SDC1 6382 syndecan 1 protein binding Molecular function 15292202 MAT2A 4144 methionine adenosyltransferase II, alpha methionine adenosyltransferase activity Molecular function 10644686 RPS4Y2 140032 ribosomal protein S4, Y-linked 2 structural constituent of ribosome Molecular function - DAZ2 57055 deleted in azoospermia 2 multicellular organismal development Biological process - APPL1 26060 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 protein binding Molecular function 10490823 FAXDC2 10826 fatty acid hydroxylase domain containing 2 fatty acid biosynthetic process Biological process - LDLR 3949 low density lipoprotein receptor clathrin-coated endocytic vesicle membrane Cellular component - GNB2L1 10399 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 positive regulation of gastrulation Biological process - BIRC6 57448 baculoviral IAP repeat containing 6 mitotic nuclear division Biological process - LITAF 9516 lipopolysaccharide-induced TNF factor aging Biological process - GGT3P 2679 gamma-glutamyltransferase 3 pseudogene proteolysis Biological process - THBS1 7057 thrombospondin 1 positive regulation of endothelial cell migration Biological process 18555217 TGFBR1 7046 transforming growth factor, beta receptor 1 in utero embryonic development Biological process - MEN1 4221 multiple endocrine neoplasia I Y-form DNA binding Molecular function 15331604 DAPP1 27071 dual adaptor of phosphotyrosine and 3-phosphoinositides phosphatidylinositol-3,4-bisphosphate binding Molecular function 17823121 DNM1L 10059 dynamin 1-like peroxisome Cellular component 23921378 USP13 8975 ubiquitin specific peptidase 13 (isopeptidase T-3) zinc ion binding Molecular function - MED1 5469 mediator complex subunit 1 cellular lipid metabolic process Biological process - ESRRA 2101 estrogen-related receptor alpha intracellular receptor signaling pathway Biological process 9286700 SMAD3 4088 SMAD family member 3 negative regulation of inflammatory response Biological process - RDX 5962 radixin apical protein localization Biological process - AURKAIP1 54998 aurora kinase A interacting protein 1 organelle organization Biological process - ZDHHC21 340481 zinc finger, DHHC-type containing 21 palmitoyltransferase activity Molecular function 23034182 PRR13 54458 proline rich 13 protein binding Molecular function 16189514 SOX9 6662 SRY (sex determining region Y)-box 9 endocrine pancreas development Biological process - STAC2 342667 SH3 and cysteine rich domain 2 metal ion binding Molecular function - NUP93 9688 nucleoporin 93kDa structural constituent of nuclear pore Molecular function 15229283 NDUFA9 4704 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa nucleus Cellular component 21630459 RPS25 6230 ribosomal protein S25 translation Biological process - JAK1 3716 Janus kinase 1 protein tyrosine kinase activity Molecular function - H6PD 9563 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) glucose 1-dehydrogenase [NAD(P)] activity Molecular function - KCND1 3750 potassium channel, voltage gated Shal related subfamily D, member 1 potassium ion transmembrane transport Biological process - GABRG3 2567 gamma-aminobutyric acid (GABA) A receptor, gamma 3 response to drug Biological process - SORD 6652 sorbitol dehydrogenase extracellular exosome Cellular component 19056867 HLA-C 3107 major histocompatibility complex, class I, C extracellular region Cellular component - S100A13 6284 S100 calcium binding protein A13 lipid binding Molecular function - CLN5 1203 ceroid-lipofuscinosis, neuronal 5 protein catabolic process Biological process 10740217 SMAD2 4087 SMAD family member 2 double-stranded DNA binding Molecular function - DRD2 1813 dopamine receptor D2 positive regulation of multicellular organism growth Biological process - PIK3CB 5291 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta chemotaxis Biological process 10570282 PHF5A 84844 PHD finger protein 5A mRNA splicing, via spliceosome Biological process - GLI4 2738 GLI family zinc finger 4 sequence-specific DNA binding transcription factor activity Molecular function - APBA3 9546 amyloid beta (A4) precursor protein-binding, family A, member 3 protein binding Molecular function 10049767 HAP1 9001 huntingtin-associated protein 1 synaptic vesicle Cellular component - RNASE3 6037 ribonuclease, RNase A family, 3 antibacterial humoral response Biological process 12860195 APOBEC3D 140564 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D negative regulation of single stranded viral RNA replication via double stranded DNA intermediate Biological process 21835787 HSP90AB1 3326 heat shock protein 90kDa alpha (cytosolic), class B member 1 virion attachment to host cell Biological process 24098578 SFT2D1 113402 SFT2 domain containing 1 protein transport Biological process - PACSIN2 11252 protein kinase C and casein kinase substrate in neurons 2 early endosome Cellular component - NRG1 3084 neuregulin 1 positive regulation of cardiac muscle cell proliferation Biological process 9553078 CCT3 7203 chaperonin containing TCP1, subunit 3 (gamma) zona pellucida receptor complex Cellular component - NTRK1 4914 neurotrophic tyrosine kinase, receptor, type 1 Sertoli cell development Biological process - DTX1 1840 deltex 1, E3 ubiquitin ligase transcription coactivator activity Molecular function 9590294 KIRREL3 84623 kin of IRRE like 3 (Drosophila) extracellular region Cellular component - ZFP37 7539 ZFP37 zinc finger protein transcription, DNA-templated Biological process - CLK2 1196 CDC-like kinase 2 protein autophosphorylation Biological process - EPHB3 2049 EPH receptor B3 positive regulation of synapse assembly Biological process - CETP 1071 cholesteryl ester transfer protein, plasma reverse cholesterol transport Biological process 7583561 ZNF638 27332 zinc finger protein 638 nucleoplasm Cellular component - MYO5B 4645 myosin VB metabolic process Biological process - MAL2 114569 mal, T-cell differentiation protein 2 (gene/pseudogene) extracellular exosome Cellular component 19056867 KRAS 3845 Kirsten rat sarcoma viral oncogene homolog blood coagulation Biological process - SLC2A10 81031 solute carrier family 2 (facilitated glucose transporter), member 10 glucose import Biological process - LTK 4058 leukocyte receptor tyrosine kinase transmembrane receptor protein tyrosine kinase signaling pathway Biological process - FASTKD3 79072 FAST kinase domains 3 protein kinase activity Molecular function - ERBB2 2064 erb-b2 receptor tyrosine kinase 2 protein phosphorylation Biological process 10851066 REPIN1 29803 replication initiator 1 DNA replication Biological process - UBE2J2 118424 ubiquitin-conjugating enzyme E2, J2 positive regulation of protein targeting to mitochondrion Biological process 24270810 SYNDIG1 79953 synapse differentiation inducing 1 early endosome membrane Cellular component - NGF 4803 nerve growth factor (beta polypeptide) metalloendopeptidase inhibitor activity Molecular function 20164177 IVNS1ABP 10625 influenza virus NS1A binding protein response to virus Biological process 9696811 GRIN2B 2904 glutamate receptor, ionotropic, N-methyl D-aspartate 2B learning or memory Biological process 10485705 WNT9A 7483 wingless-type MMTV integration site family, member 9A embryonic skeletal system morphogenesis Biological process - RHO 6010 rhodopsin rough endoplasmic reticulum membrane Cellular component - MTFR1 9650 mitochondrial fission regulator 1 aerobic respiration Biological process - SRY 6736 sex determining region Y nucleoplasm Cellular component - BTN2A2 10385 butyrophilin, subfamily 2, member A2 integral component of membrane Cellular component - SNCA 6622 synuclein, alpha (non A4 component of amyloid precursor) phosphoprotein binding Molecular function 21127069 PPM1G 5496 protein phosphatase, Mg2+/Mn2+ dependent, 1G protein serine/threonine phosphatase activity Molecular function 20801214 CALCRL 10203 calcitonin receptor-like calcitonin receptor activity Molecular function - IL6 3569 interleukin 6 positive regulation of T cell proliferation Biological process 3130269 PCBP3 54039 poly(rC) binding protein 3 extracellular exosome Cellular component 23533145 PCK2 5106 phosphoenolpyruvate carboxykinase 2 (mitochondrial) GTP binding Molecular function - CYP46A1 10858 cytochrome P450, family 46, subfamily A, polypeptide 1 endoplasmic reticulum membrane Cellular component - SRI 6717 sorcin protein heterodimerization activity Molecular function 12804766 RXRG 6258 retinoid X receptor, gamma protein homotetramerization Biological process - CD58 965 CD58 molecule cell surface Cellular component 15345303 KHSRP 8570 KH-type splicing regulatory protein RNA splicing Biological process 10911989 PLCB1 23236 phospholipase C, beta 1 (phosphoinositide-specific) interleukin-1-mediated signaling pathway Biological process 8872139 CALM3 808 calmodulin 3 (phosphorylase kinase, delta) spindle microtubule Cellular component 16760425 NFXL1 152518 nuclear transcription factor, X-box binding-like 1 nucleus Cellular component - APBB1 322 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) regulation of transcription, DNA-templated Biological process - GFRAL 389400 GDNF family receptor alpha like negative regulation of neuron apoptotic process Biological process - PURA 5813 purine-rich element binding protein A DNA unwinding involved in DNA replication Biological process 15777841 ZBTB18 10472 zinc finger and BTB domain containing 18 nucleus Cellular component 9013868 MFSD2A 84879 major facilitator superfamily domain containing 2A cytoplasm Cellular component - OR1J2 26740 olfactory receptor, family 1, subfamily J, member 2 detection of chemical stimulus involved in sensory perception Biological process - FKBP15 23307 FK506 binding protein 15, 133kDa axon Cellular component - GLI2 2736 GLI family zinc finger 2 tube development Biological process - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide retina vasculature development in camera-type eye Biological process - ARHGAP4 393 Rho GTPase activating protein 4 GTPase activator activity Molecular function - ZNF677 342926 zinc finger protein 677 sequence-specific DNA binding transcription factor activity Molecular function - CHP1 11261 calcineurin-like EF-hand protein 1 hyaluronan metabolic process Biological process - NDOR1 27158 NADPH dependent diflavin oxidoreductase 1 intermediate filament cytoskeleton Cellular component - LY6H 4062 lymphocyte antigen 6 complex, locus H organ morphogenesis Biological process 9799603 CAPN3 825 calpain 3, (p94) structural constituent of muscle Molecular function - TRAF7 84231 TNF receptor-associated factor 7, E3 ubiquitin protein ligase apoptotic process Biological process 15001576 KIR2DL4 3805 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 cellular defense response Biological process 8946682 SRRM1 10250 serine/arginine repetitive matrix 1 nucleoplasm Cellular component - H1FNT 341567 H1 histone family, member N, testis-specific DNA binding Molecular function - AGPAT5 55326 1-acylglycerol-3-phosphate O-acyltransferase 5 integral component of membrane Cellular component - CCND3 896 cyclin D3 cell division Biological process - DAB1 1600 Dab, reelin signal transducer, homolog 1 (Drosophila) postsynaptic density Cellular component - ROPN1B 152015 rhophilin associated tail protein 1B Rho protein signal transduction Biological process 11278869 NCOA3 8202 nuclear receptor coactivator 3 protein dimerization activity Molecular function - TRIM32 22954 tripartite motif containing 32 ubiquitin protein ligase activity Molecular function 16816390 DOC2B 8447 double C2-like domains, beta calcium ion binding Molecular function - EGFR 1956 epidermal growth factor receptor positive regulation of phosphorylation Biological process 15082764 PSMA8 143471 proteasome (prosome, macropain) subunit, alpha type, 8 negative regulation of canonical Wnt signaling pathway Biological process - ZRANB2 9406 zinc finger, RAN-binding domain containing 2 RNA splicing Biological process - TRMU 55687 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase tRNA methylation Biological process - GALNT3 2591 polypeptide N-acetylgalactosaminyltransferase 3 carbohydrate binding Molecular function - WDR62 284403 WD repeat domain 62 neurogenesis Biological process 20890278 PRR5L 79899 proline rich 5 like TORC2 signaling Biological process 22609986 LRPPRC 10128 leucine-rich pentatricopeptide repeat containing microtubule binding Molecular function 12762840 GPS2 2874 G protein pathway suppressor 2 negative regulation of GTPase activity Biological process 8943324 CD109 135228 CD109 molecule anchored component of membrane Cellular component - BUB1 699 BUB1 mitotic checkpoint serine/threonine kinase apoptotic process Biological process - MSH5 4439 mutS homolog 5 ATP binding Molecular function - IL7 3574 interleukin 7 protein binding Molecular function 8266077 PTPN1 5770 protein tyrosine phosphatase, non-receptor type 1 negative regulation of insulin receptor signaling pathway Biological process 11742412 ERCC2 2068 excision repair cross-complementation group 2 spinal cord development Biological process - TMED5 50999 transmembrane emp24 protein transport domain containing 5 Golgi ribbon formation Biological process 19948005 ABCG1 9619 ATP-binding cassette, sub-family G (WHITE), member 1 Golgi apparatus Cellular component - MMP15 4324 matrix metallopeptidase 15 (membrane-inserted) collagen catabolic process Biological process - PPIF 10105 peptidylprolyl isomerase F response to ischemia Biological process - JUN 3725 jun proto-oncogene RNA polymerase II activating transcription factor binding Molecular function 19861239 FRS2 10818 fibroblast growth factor receptor substrate 2 endosome Cellular component - UBE2A 7319 ubiquitin-conjugating enzyme E2A positive regulation of cell proliferation Biological process 11953320 TREM1 54210 triggering receptor expressed on myeloid cells 1 scaffold protein binding Molecular function 11602640 KCNE1 3753 potassium channel, voltage gated subfamily E regulatory beta subunit 1 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization Molecular function 10400998 SLC12A2 6558 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 extracellular vesicle Cellular component 24769233 PCGF6 84108 polycomb group ring finger 6 RNA polymerase II regulatory region sequence-specific DNA binding Molecular function - CD74 972 CD74 molecule, major histocompatibility complex, class II invariant chain immunoglobulin mediated immune response Biological process - PAPOLB 56903 poly(A) polymerase beta (testis specific) nucleus Cellular component - GYS1 2997 glycogen synthase 1 (muscle) carbohydrate metabolic process Biological process - PNPLA3 80339 patatin-like phospholipase domain containing 3 small molecule metabolic process Biological process - ECE2 9718 endothelin converting enzyme 2 heart development Biological process - RECQL4 9401 RecQ protein-like 4 ATP binding Molecular function 19177149 AMIGO2 347902 adhesion molecule with Ig-like domain 2 homophilic cell adhesion via plasma membrane adhesion molecules Biological process 12629050 TP63 8626 tumor protein p63 protein homotetramerization Biological process 10373484 SRP72 6731 signal recognition particle 72kDa signal recognition particle, endoplasmic reticulum targeting Cellular component 18089836 FBXL7 23194 F-box and leucine-rich repeat protein 7 ubiquitin ligase complex Cellular component 10531035 UNKL 64718 unkempt family zinc finger-like zinc ion binding Molecular function - STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced mammary gland morphogenesis Biological process - THY1 7070 Thy-1 cell surface antigen extracellular exosome Cellular component 19056867 E4F1 1877 E4F transcription factor 1 regulation of mitotic cell cycle, embryonic Biological process - UVSSA 57654 UV-stimulated scaffold protein A response to UV Biological process 22466610 MUC7 4589 mucin 7, secreted protein O-linked glycosylation Biological process - MGST2 4258 microsomal glutathione S-transferase 2 glutathione derivative biosynthetic process Biological process - NBL1 4681 neuroblastoma 1, DAN family BMP antagonist negative regulation of monocyte chemotaxis Biological process - BID 637 BH3 interacting domain death agonist glial cell apoptotic process Biological process - LY96 23643 lymphocyte antigen 96 innate immune response Biological process - PRKRIR 5612 protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) DNA binding Molecular function - MEX3D 399664 mex-3 RNA binding family member D mRNA destabilization Biological process 14769789 POLR3K 51728 polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa zinc ion binding Molecular function - GPD1L 23171 glycerol-3-phosphate dehydrogenase 1-like glycerol-3-phosphate dehydrogenase complex Cellular component - TAC1 6863 tachykinin, precursor 1 positive regulation of synaptic transmission, cholinergic Biological process - EDEM2 55741 ER degradation enhancer, mannosidase alpha-like 2 response to unfolded protein Biological process - CLN6 54982 ceroid-lipofuscinosis, neuronal 6, late infantile, variant protein binding Molecular function 19235893 TFAM 7019 transcription factor A, mitochondrial poly(A) RNA binding Molecular function 22658674 DNA2 1763 DNA replication helicase/nuclease 2 site-specific endodeoxyribonuclease activity, specific for altered base Molecular function 18995831 TXN2 25828 thioredoxin 2 protein disulfide oxidoreductase activity Molecular function - ATF4 468 activating transcription factor 4 endoplasmic reticulum unfolded protein response Biological process - SEMA6B 10501 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B semaphorin receptor binding Molecular function - DAPK3 1613 death-associated protein kinase 3 protein phosphorylation Biological process 10356987 CBX5 23468 chromobox homolog 5 chromocenter Cellular component - TDRD9 122402 tudor domain containing 9 cytoplasm Cellular component - MCM8 84515 minichromosome maintenance complex component 8 mitotic cell cycle Biological process - TMEM115 11070 transmembrane protein 115 negative regulation of cell proliferation Biological process 17973242 MUC5AC 4586 mucin 5AC, oligomeric mucus/gel-forming cytoplasm Cellular component 25591774 MAPK1 5594 mitogen-activated protein kinase 1 neurotrophin TRK receptor signaling pathway Biological process - C5AR1 728 complement component 5a receptor 1 immune response Biological process 9590258 SLC8A1 6546 solute carrier family 8 (sodium/calcium exchanger), member 1 regulation of cardiac muscle contraction by calcium ion signaling Biological process 23224879 CCNT1 904 cyclin T1 protein binding Molecular function 12944466 SMARCD3 6604 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 cytoplasm Cellular component 17363140 SOD1 6647 superoxide dismutase 1, soluble regulation of GTPase activity Biological process 18219391 TBC1D30 23329 TBC1 domain family, member 30 GTPase activator activity Molecular function 17646400 THBS1 7057 thrombospondin 1 positive regulation of phosphorylation Biological process 17413041 MBD3L1 85509 methyl-CpG binding domain protein 3-like 1 nucleoplasm Cellular component - CNOT8 9337 CCR4-NOT transcription complex, subunit 8 poly(A)-specific ribonuclease activity Molecular function 15769875 LGR4 55366 leucine-rich repeat containing G protein-coupled receptor 4 negative regulation of toll-like receptor signaling pathway Biological process - ZNF181 339318 zinc finger protein 181 transcription, DNA-templated Biological process - DGKZ 8525 diacylglycerol kinase, zeta intracellular signal transduction Biological process - CCDC86 79080 coiled-coil domain containing 86 protein binding Molecular function 15607035 MTFR2 113115 mitochondrial fission regulator 2 mitochondrion Cellular component - XPO1 7514 exportin 1 nucleoplasm Cellular component - FAIM2 23017 Fas apoptotic inhibitory molecule 2 postsynaptic membrane Cellular component - LAMB1 3912 laminin, beta 1 positive regulation of cell migration Biological process 16289578 MYC 4609 v-myc avian myelocytomatosis viral oncogene homolog RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 10723141 AOC3 8639 amine oxidase, copper containing 3 protein homodimerization activity Molecular function 9653080 DIAPH3 81624 diaphanous-related formin 3 small GTPase mediated signal transduction Biological process - ADH7 131 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide small molecule metabolic process Biological process - PTPRJ 5795 protein tyrosine phosphatase, receptor type, J negative regulation of T cell receptor signaling pathway Biological process 11259588 PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 positive regulation of transcription, DNA-templated Biological process 7870181 CCM2 83605 cerebral cavernous malformation 2 pericardium development Biological process - ATP5F1 515 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 cellular metabolic process Biological process - MRPS34 65993 mitochondrial ribosomal protein S34 mitochondrion Cellular component - TCF21 6943 transcription factor 21 morphogenesis of a branching structure Biological process - ETFB 2109 electron-transfer-flavoprotein, beta polypeptide mitochondrion Cellular component - CBFB 865 core-binding factor, beta subunit membrane Cellular component 19946888 ANKRD2 26287 ankyrin repeat domain 2 (stretch responsive muscle) I band Cellular component - COL14A1 7373 collagen, type XIV, alpha 1 ventricular cardiac muscle tissue development Biological process - SURF4 6836 surfeit 4 positive regulation of organelle organization Biological process 18287528 KCTD14 65987 potassium channel tetramerization domain containing 14 protein homooligomerization Biological process - GPR34 2857 G protein-coupled receptor 34 G-protein coupled purinergic nucleotide receptor activity Molecular function - CDK9 1025 cyclin-dependent kinase 9 DNA binding Molecular function 16109376 EPHB6 2051 EPH receptor B6 plasma membrane Cellular component - ZNF235 9310 zinc finger protein 235 regulation of transcription, DNA-templated Biological process - NAA60 79903 N(alpha)-acetyltransferase 60, NatF catalytic subunit nucleosome assembly Biological process 21981917 PDX1 3651 pancreatic and duodenal homeobox 1 liver development Biological process - SHQ1 55164 SHQ1, H/ACA ribonucleoprotein assembly factor positive regulation of apoptotic process Biological process 20663920 PRDX4 10549 peroxiredoxin 4 male gonad development Biological process - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide nucleus Cellular component - WIZ 58525 widely interspaced zinc finger motifs positive regulation of nuclear cell cycle DNA replication Biological process 23545495 TMED10 10972 transmembrane emp24-like trafficking protein 10 (yeast) kidney development Biological process - PRKACA 5566 protein kinase, cAMP-dependent, catalytic, alpha regulation of bicellular tight junction assembly Biological process 15905176 NHP2L1 4809 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) ribosome biogenesis Biological process - ACADSB 36 acyl-CoA dehydrogenase, short/branched chain oxidation-reduction process Biological process - APOA5 116519 apolipoprotein A-V lipase activator activity Molecular function 15178420 BCAS2 10286 breast carcinoma amplified sequence 2 RNA splicing Biological process 9731529 PBX1 5087 pre-B-cell leukemia homeobox 1 cytoplasm Cellular component 18973687 APOA5 116519 apolipoprotein A-V acylglycerol homeostasis Biological process 15178420 LGALS14 56891 lectin, galactoside-binding, soluble, 14 apoptotic process Biological process - MAGOH 4116 mago-nashi homolog, proliferation-associated (Drosophila) regulation of translation Biological process - KCNE2 9992 potassium channel, voltage gated subfamily E regulatory beta subunit 2 inward rectifier potassium channel activity Molecular function 10219239 UBA2 10054 ubiquitin-like modifier activating enzyme 2 transcription factor binding Molecular function - RASD2 23551 RASD family, member 2 ubiquitin conjugating enzyme binding Molecular function - SOX3 6658 SRY (sex determining region Y)-box 3 RNA polymerase II core promoter sequence-specific DNA binding Molecular function - ZNF224 7767 zinc finger protein 224 nucleoplasm Cellular component - ATAD1 84896 ATPase family, AAA domain containing 1 memory Biological process - CD14 929 CD14 molecule extracellular exosome Cellular component 19056867 EXD3 54932 exonuclease 3'-5' domain containing 3 nucleus Cellular component - ZMYM6NB 100506144 ZMYM6 neighbor integral component of membrane Cellular component - LMO7 4008 LIM domain 7 protein ubiquitination Biological process 10531035 NEK4 6787 NIMA-related kinase 4 regulation of cellular senescence Biological process 22851694 TOR1A 1861 torsin family 1, member A (torsin A) protein homooligomerization Biological process 20015956 ATOH7 220202 atonal homolog 7 (Drosophila) protein dimerization activity Molecular function - PSEN1 5663 presenilin 1 beta-catenin binding Molecular function 11104755 AHR 196 aryl hydrocarbon receptor regulation of transcription from RNA polymerase II promoter Biological process 15681594 CRHBP 1393 corticotropin releasing hormone binding protein multivesicular body Cellular component - DOHH 83475 deoxyhypusine hydroxylase/monooxygenase oxidation-reduction process Biological process - CTSB 1508 cathepsin B nucleolus Cellular component - RPS12 6206 ribosomal protein S12 viral transcription Biological process - KLRG1 10219 killer cell lectin-like receptor subfamily G, member 1 protein binding Molecular function 25416956 BANF2 140836 barrier to autointegration factor 2 nucleus Cellular component 21630459 PDK3 5165 pyruvate dehydrogenase kinase, isozyme 3 regulation of acetyl-CoA biosynthetic process from pyruvate Biological process - NLRP3 114548 NLR family, pyrin domain containing 3 NLRP3 inflammasome complex Cellular component 15030775 IL13 3596 interleukin 13 positive regulation of connective tissue growth factor production Biological process - STRA8 346673 stimulated by retinoic acid 8 DNA replication Biological process - ZBTB18 10472 zinc finger and BTB domain containing 18 regulation of cell division Biological process - SLC34A1 6569 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 protein complex binding Molecular function - ADAMTS7 11173 ADAM metallopeptidase with thrombospondin type 1 motif, 7 cellular protein metabolic process Biological process - MVB12A 93343 multivesicular body subunit 12A ubiquitin binding Molecular function 20654576 NLGN4X 57502 neuroligin 4, X-linked synapse organization Biological process 11368788 PLCB3 5331 phospholipase C, beta 3 (phosphatidylinositol-specific) intracellular signal transduction Biological process - BCL10 8915 B-cell CLL/lymphoma 10 positive regulation of interleukin-8 biosynthetic process Biological process 17095757 STIM2 57620 stromal interaction molecule 2 calcium ion binding Molecular function 18166150 PKD2L1 9033 polycystic kidney disease 2-like 1 protein binding Molecular function 12525172 DNA2 1763 DNA replication helicase/nuclease 2 mitochondrial DNA repair Biological process 19487465 SHISA5 51246 shisa family member 5 WW domain binding Molecular function 15064722 TRPV5 56302 transient receptor potential cation channel, subfamily V, member 5 integral component of plasma membrane Cellular component 15489237 CHRM2 1129 cholinergic receptor, muscarinic 2 integral component of plasma membrane Cellular component 24256733 ONECUT1 3175 one cut homeobox 1 B cell differentiation Biological process - CDX2 1045 caudal type homeobox 2 establishment or maintenance of epithelial cell apical/basal polarity Biological process - FEZ1 9638 fasciculation and elongation protein zeta 1 (zygin I) transport Biological process - MMAA 166785 methylmalonic aciduria (cobalamin deficiency) cblA type cobalamin metabolic process Biological process - TLR9 54106 toll-like receptor 9 positive regulation of JUN kinase activity Biological process 17128265 APOE 348 apolipoprotein E heparin binding Molecular function 2745454 PALM2 114299 paralemmin 2 regulation of cell shape Biological process - DLG5 9231 discs, large homolog 5 (Drosophila) regulation of apoptotic process Biological process - FOXB1 27023 forkhead box B1 transcription from RNA polymerase II promoter Biological process - ZNF597 146434 zinc finger protein 597 regulation of transcription, DNA-templated Biological process - NONO 4841 non-POU domain containing, octamer-binding nucleus Cellular component - OVOS 408186 ovostatin negative regulation of endopeptidase activity Biological process - NRXN1 9378 neurexin 1 neuronal signal transduction Biological process 15797875 MPP7 143098 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) positive regulation of protein complex assembly Biological process 14719143 MRPL27 51264 mitochondrial ribosomal protein L27 mitochondrial inner membrane Cellular component - ITPKC 80271 inositol-trisphosphate 3-kinase C activation of mitophagy in response to mitochondrial depolarization Biological process 22020285 MT3 4504 metallothionein 3 protein import into nucleus, translocation Biological process 18554677 NELL1 4745 NEL-like 1 (chicken) extracellular region Cellular component - ARL8B 55207 ADP-ribosylation factor-like 8B alpha-tubulin binding Molecular function 15331635 AGO1 26523 argonaute RISC catalytic component 1 RISC-loading complex Cellular component 19966796 IFT140 9742 intraflagellar transport 140 cilium assembly Biological process - STC1 6781 stanniocalcin 1 apical plasma membrane Cellular component - VTI1B 10490 vesicle transport through interaction with t-SNAREs 1B protein targeting to vacuole Biological process - GNG3 2785 guanine nucleotide binding protein (G protein), gamma 3 plasma membrane Cellular component - KDELR3 11015 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 IRE1-mediated unfolded protein response Biological process - TFAP2D 83741 transcription factor AP-2 delta (activating enhancer binding protein 2 delta) sequence-specific DNA binding RNA polymerase II transcription factor activity Molecular function - RPS18 6222 ribosomal protein S18 cytosolic small ribosomal subunit Cellular component 15883184 DUSP4 1846 dual specificity phosphatase 4 toll-like receptor 5 signaling pathway Biological process - OVOL3 728361 ovo-like zinc finger 3 regulation of transcription from RNA polymerase II promoter Biological process - ATP1A3 478 ATPase, Na+/K+ transporting, alpha 3 polypeptide sodium:potassium-exchanging ATPase activity Molecular function 15260953 MAPK8IP1 9479 mitogen-activated protein kinase 8 interacting protein 1 mitochondrial membrane Cellular component - LRRC8A 56262 leucine rich repeat containing 8 family, member A cell volume homeostasis Biological process 24725410 CBL 867 Cbl proto-oncogene, E3 ubiquitin protein ligase protein binding Molecular function 10068674 ECE1 1889 endothelin converting enzyme 1 pharyngeal system development Biological process - RALB 5899 v-ral simian leukemia viral oncogene homolog B positive regulation of protein serine/threonine kinase activity Biological process 24056301 FBXW8 26259 F-box and WD repeat domain containing 8 protein ubiquitination Biological process - ZFAND2B 130617 zinc finger, AN1-type domain 2B protein binding Molecular function 16189514 GDF2 2658 growth differentiation factor 2 blood vessel morphogenesis Biological process 20406889 APC 324 adenomatous polyposis coli bicellular tight junction Cellular component 18502210 TAC1 6863 tachykinin, precursor 1 associative learning Biological process - FOXF1 2294 forkhead box F1 positive regulation of cell-substrate adhesion Biological process - OR52E4 390081 olfactory receptor, family 52, subfamily E, member 4 integral component of membrane Cellular component - COQ6 51004 coenzyme Q6 monooxygenase mitochondrial inner membrane Cellular component - TMEM120B 144404 transmembrane protein 120B cellular_component Cellular component - NDNF 79625 neuron-derived neurotrophic factor cell growth Biological process 20969804 ZNF138 7697 zinc finger protein 138 transcription, DNA-templated Biological process - RPS18 6222 ribosomal protein S18 rRNA binding Molecular function - PRL 5617 prolactin cell surface receptor signaling pathway Biological process 10854700 PAX6 5080 paired box 6 eye development Biological process 10747901 CHRNB1 1140 cholinergic receptor, nicotinic, beta 1 (muscle) postsynaptic membrane organization Biological process 8651643 VAPA 9218 VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa FFAT motif binding Molecular function 18713837 KLHL5 51088 kelch-like family member 5 actin binding Molecular function - USP8 9101 ubiquitin specific peptidase 8 early endosome Cellular component 16520378 HIST1H4K 8362 histone cluster 1, H4k nuclear chromosome Cellular component 14718166 NEK2 4751 NIMA-related kinase 2 cell division Biological process - PRKACB 5567 protein kinase, cAMP-dependent, catalytic, beta plasma membrane Cellular component - WWC2 80014 WW and C2 domain containing 2 negative regulation of organ growth Biological process 24682284 GPCPD1 56261 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) starch binding Molecular function - MEN1 4221 multiple endocrine neoplasia I leukocyte homeostasis Biological process - GGT2 728441 gamma-glutamyltransferase 2 small molecule metabolic process Biological process - QRFP 347148 pyroglutamylated RFamide peptide neuropeptide hormone activity Molecular function 14657341 SLC24A1 9187 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 phototransduction, visible light Biological process - CTSB 1508 cathepsin B extracellular matrix disassembly Biological process - PTK2B 2185 protein tyrosine kinase 2 beta regulation of inositol trisphosphate biosynthetic process Biological process - SLC3A1 6519 solute carrier family 3 (amino acid transporter heavy chain), member 1 catalytic activity Molecular function - SLC15A4 121260 solute carrier family 15 (oligopeptide transporter), member 4 L-histidine transmembrane transport Biological process - FGB 2244 fibrinogen beta chain positive regulation of protein secretion Biological process 19193866 RAB18 22931 RAB18, member RAS oncogene family plasma membrane Cellular component - RPL41 6171 ribosomal protein L41 viral life cycle Biological process - RBM3 5935 RNA binding motif (RNP1, RRM) protein 3 translation Biological process - TACR2 6865 tachykinin receptor 2 tachykinin receptor activity Molecular function 8307161 CCM2 83605 cerebral cavernous malformation 2 endothelial tube morphogenesis Biological process 19151727 ST20 400410 suppressor of tumorigenicity 20 protein homodimerization activity Molecular function - PAK1 5058 p21 protein (Cdc42/Rac)-activated kinase 1 protein complex Cellular component 11864573 DDX11 1663 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 extracellular exosome Cellular component 18570454 AKAP3 10566 A kinase (PRKA) anchor protein 3 single fertilization Biological process 10319321 UBC 7316 ubiquitin C circadian rhythm Biological process - JUN 3725 jun proto-oncogene positive regulation of DNA replication Biological process - CAD 790 carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase cellular response to drug Biological process - CCDC59 29080 coiled-coil domain containing 59 poly(A) RNA binding Molecular function 22658674 EIF5 1983 eukaryotic translation initiation factor 5 protein binding Molecular function 25416956 ACOT12 134526 acyl-CoA thioesterase 12 pyruvate metabolic process Biological process - EPHB1 2047 EPH receptor B1 extracellular exosome Cellular component 20458337 LPGAT1 9926 lysophosphatidylglycerol acyltransferase 1 endoplasmic reticulum membrane Cellular component - PRDM14 63978 PR domain containing 14 metal ion binding Molecular function - SPARC 6678 secreted protein, acidic, cysteine-rich (osteonectin) cell surface Cellular component 15389586 ABL1 25 ABL proto-oncogene 1, non-receptor tyrosine kinase muscle cell differentiation Biological process - MUC12 10071 mucin 12, cell surface associated O-glycan processing Biological process - PEX26 55670 peroxisomal biogenesis factor 26 protein complex binding Molecular function 16854980 PCTP 58488 phosphatidylcholine transfer protein phosphatidylcholine transporter activity Molecular function 10500206 SNX25 83891 sorting nexin 25 protein transport Biological process - PAX8 7849 paired box 8 positive regulation of metanephric DCT cell differentiation Biological process - ATXN3L 92552 ataxin 3-like mitochondrial matrix Cellular component - APC 324 adenomatous polyposis coli cell-cell adherens junction Cellular component 16611247 IFT20 90410 intraflagellar transport 20 smoothened signaling pathway Biological process - GSK3B 2932 glycogen synthase kinase 3 beta tau protein binding Molecular function - ZNF730 100129543 zinc finger protein 730 DNA binding Molecular function - ZNF774 342132 zinc finger protein 774 DNA binding Molecular function - PKD1 5310 polycystic kidney disease 1 (autosomal dominant) mesonephric tubule development Biological process 11891195 CLIC5 53405 chloride intracellular channel 5 cell cortex Cellular component - CRYBB1 1414 crystallin, beta B1 structural constituent of eye lens Molecular function - GLI3 2737 GLI family zinc finger 3 primary cilium Cellular component - AKR1B10 57016 aldo-keto reductase family 1, member B10 (aldose reductase) oxidation-reduction process Biological process - FAM129A 116496 family with sequence similarity 129, member A extracellular exosome Cellular component 19199708 HNRNPD 3184 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) gene expression Biological process - PRKCG 5582 protein kinase C, gamma protein kinase activity Molecular function 15808853 NCOA6 23054 nuclear receptor coactivator 6 myeloid cell differentiation Biological process 11302752 SRC 6714 SRC proto-oncogene, non-receptor tyrosine kinase negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 19767770 CCL13 6357 chemokine (C-C motif) ligand 13 extracellular space Cellular component - NPTX1 4884 neuronal pentraxin I transport Biological process 8884281 IRAK2 3656 interleukin-1 receptor-associated kinase 2 toll-like receptor 10 signaling pathway Biological process - LZTFL1 54585 leucine zipper transcription factor-like 1 cytosol Cellular component - FASLG 356 Fas ligand (TNF superfamily, member 6) cytokine activity Molecular function - MCM7 4176 minichromosome maintenance complex component 7 ATP binding Molecular function - PEX2 5828 peroxisomal biogenesis factor 2 cholesterol homeostasis Biological process - IFNA2 3440 interferon, alpha 2 extracellular space Cellular component - HTRA2 27429 HtrA serine peptidase 2 regulation of mitochondrion degradation Biological process 24522549 ARHGAP1 392 Rho GTPase activating protein 1 extracellular exosome Cellular component 19056867 GRM8 2918 glutamate receptor, metabotropic 8 group III metabotropic glutamate receptor activity Molecular function - PTPRB 5787 protein tyrosine phosphatase, receptor type, B dephosphorylation Biological process 19116766 ANXA9 8416 annexin A9 cell surface Cellular component 10899159 DTWD2 285605 DTW domain containing 2 positive regulation of protein targeting to mitochondrion Biological process 24270810 SPAG4 6676 sperm associated antigen 4 integral component of membrane Cellular component - TINAGL1 64129 tubulointerstitial nephritis antigen-like 1 lysosome Cellular component - TBK1 29110 TANK-binding kinase 1 protein binding Molecular function 14743216 HIST1H2BN 8341 histone cluster 1, H2bn chromatin organization Biological process - TAF1C 9013 TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa DNA binding Molecular function - SLC7A10 56301 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 ion transport Biological process - SULT1A2 6799 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 steroid metabolic process Biological process - RNF225 646862 ring finger protein 225 integral component of membrane Cellular component - UCP3 7352 uncoupling protein 3 (mitochondrial, proton carrier) response to glucocorticoid Biological process - LPA 4018 lipoprotein, Lp(a) mononuclear cell migration Biological process - NUP62 23636 nucleoporin 62kDa ubiquitin binding Molecular function - TBX18 9096 T-box 18 somitogenesis Biological process - ZNF624 57547 zinc finger protein 624 metal ion binding Molecular function - COL11A2 1302 collagen, type XI, alpha 2 sensory perception of sound Biological process 10581026 JAK2 3717 Janus kinase 2 positive regulation of sequence-specific DNA binding transcription factor activity Biological process - MAGED1 9500 melanoma antigen family D1 negative regulation of transcription, DNA-templated Biological process - JUP 3728 junction plakoglobin bundle of His cell-Purkinje myocyte adhesion involved in cell communication Biological process 17924338 PTGS2 5743 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) inflammatory response Biological process - ADGRG1 9289 adhesion G protein-coupled receptor G1 collagen binding Molecular function - HSPG2 3339 heparan sulfate proteoglycan 2 chondroitin sulfate metabolic process Biological process - NR2F6 2063 nuclear receptor subfamily 2, group F, member 6 DNA binding Molecular function 2905047 BCL2 596 B-cell CLL/lymphoma 2 cellular response to DNA damage stimulus Biological process 17875758 MAPK11 5600 mitogen-activated protein kinase 11 ATP binding Molecular function - KDELR2 11014 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 Golgi apparatus Cellular component 1316805 ZNF273 10793 zinc finger protein 273 nucleus Cellular component - RPS9 6203 ribosomal protein S9 cytosol Cellular component - POU3F3 5455 POU class 3 homeobox 3 positive regulation of transcription from RNA polymerase II promoter Biological process - HCK 3055 HCK proto-oncogene, Src family tyrosine kinase cytokine-mediated signaling pathway Biological process 18538446 AVP 551 arginine vasopressin dendrite Cellular component - SUPT20HL1 100130302 suppressor of Ty 20 homolog (S. cerevisiae)-like 1 SAGA complex Cellular component - FAM198B 51313 family with sequence similarity 198, member B Golgi apparatus Cellular component - HCRTR2 3062 hypocretin (orexin) receptor 2 feeding behavior Biological process - CHMP1A 5119 charged multivesicular body protein 1A ESCRT III complex Cellular component - ATF3 467 activating transcription factor 3 transcription regulatory region DNA binding Molecular function 8622660 WAPAL 23063 wings apart-like homolog (Drosophila) mitotic cell cycle Biological process - ARL13B 200894 ADP-ribosylation factor-like 13B heart looping Biological process - TGFB2 7042 transforming growth factor, beta 2 negative regulation of macrophage cytokine production Biological process 20875417 TNFRSF11A 8792 tumor necrosis factor receptor superfamily, member 11a, NFKB activator TNFSF11-mediated signaling pathway Biological process 18606301 CYTH2 9266 cytohesin 2 cytoplasm Cellular component 17398095 PPP5C 5536 protein phosphatase 5, catalytic subunit cytoplasm Cellular component - SOX2 6657 SRY (sex determining region Y)-box 2 sequence-specific DNA binding transcription factor activity Molecular function 7849401 LRRIQ3 127255 leucine-rich repeats and IQ motif containing 3 protein binding Molecular function 25416956 C8A 731 complement component 8, alpha polypeptide extracellular space Cellular component 6771072 DRD2 1813 dopamine receptor D2 regulation of heart rate Biological process - CDH3 1001 cadherin 3, type 1, P-cadherin (placental) positive regulation of melanin biosynthetic process Biological process 23334344 CDC42 998 cell division cycle 42 neuron fate determination Biological process - ARGLU1 55082 arginine and glutamate rich 1 mitochondrion Cellular component - MTOR 2475 mechanistic target of rapamycin (serine/threonine kinase) positive regulation of gene expression Biological process 17028174 KRT36 8689 keratin 36, type I regulation of keratinocyte differentiation Biological process - PCSK5 5125 proprotein convertase subtilisin/kexin type 5 anterior/posterior pattern specification Biological process 18519639 ERCC3 2071 excision repair cross-complementation group 3 transcription from RNA polymerase I promoter Biological process - CHST2 9435 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 sulfotransferase activity Molecular function 9722682 E2F7 144455 E2F transcription factor 7 nucleus Cellular component - MIF 4282 macrophage migration inhibitory factor (glycosylation-inhibiting factor) positive regulation of protein kinase A signaling Biological process 17045821 BRCA2 675 breast cancer 2, early onset DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator Biological process - SGK1 6446 serum/glucocorticoid regulated kinase 1 long-term memory Biological process 20530112 BHLHA9 727857 basic helix-loop-helix family, member a9 transcription, DNA-templated Biological process - CISH 1154 cytokine inducible SH2-containing protein plasma membrane Cellular component - FAM90A23P 645572 family with sequence similarity 90, member A23 pseudogene zinc ion binding Molecular function - GBP2 2634 guanylate binding protein 2, interferon-inducible type I interferon signaling pathway Biological process - PTCH1 5727 patched 1 heart morphogenesis Biological process - SEMA5B 54437 sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B cell differentiation Biological process - HDAC4 9759 histone deacetylase 4 protein binding Molecular function 10869435 LCK 3932 LCK proto-oncogene, Src family tyrosine kinase positive regulation of intrinsic apoptotic signaling pathway Biological process - NT5C2 22978 5'-nucleotidase, cytosolic II protein binding Molecular function 16189514 PSMA8 143471 proteasome (prosome, macropain) subunit, alpha type, 8 antigen processing and presentation of exogenous peptide antigen via MHC class I Biological process - SERPINA5 5104 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 serine-type endopeptidase inhibitor activity Molecular function 10340997 GP5 2814 glycoprotein V (platelet) plasma membrane Cellular component - ARID3A 1820 AT rich interactive domain 3A (BRIGHT-like) protein binding Molecular function 19214191 HES5 388585 hes family bHLH transcription factor 5 specification of loop of Henle identity Biological process - AVPR2 554 arginine vasopressin receptor 2 positive regulation of protein ubiquitination Biological process 19372219 HEXIM1 10614 hexamethylene bis-acetamide inducible 1 nucleoplasm Cellular component - ADAMTS1 9510 ADAM metallopeptidase with thrombospondin type 1 motif, 1 cytoplasmic vesicle Cellular component - HDAC10 83933 histone deacetylase 10 regulation of transcription, DNA-templated Biological process 11861901 RBFOX2 23543 RNA binding protein, fox-1 homolog (C. elegans) 2 RNA binding Molecular function 11875103 CLPP 8192 caseinolytic mitochondrial matrix peptidase proteolytic subunit protein binding Molecular function 11923310 TNNI3 7137 troponin I type 3 (cardiac) sarcomere Cellular component 16754800 TFCP2 7024 transcription factor CP2 sequence-specific DNA binding transcription factor activity Molecular function 8157699 EXOC6 54536 exocyst complex component 6 membrane organization Biological process - CXXC1 30827 CXXC finger protein 1 regulation of transcription, DNA-templated Biological process 10688657 POLR2L 5441 polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa viral process Biological process - PINK1 65018 PTEN induced putative kinase 1 regulation of synaptic vesicle transport Biological process 21563316 HOXB3 3213 homeobox B3 anterior/posterior pattern specification Biological process - GSKIP 51527 GSK3B interacting protein cytoplasm Cellular component - GAS6 2621 growth arrest-specific 6 protein targeting to plasma membrane Biological process 16359517 NIFK 84365 nucleolar protein interacting with the FHA domain of MKI67 condensed nuclear chromosome Cellular component 11342549 PKN2 5586 protein kinase N2 RNA polymerase binding Molecular function 15364941 PPP3R1 5534 protein phosphatase 3, regulatory subunit B, alpha positive regulation of NFAT protein import into nucleus Biological process 22688515 GATM 2628 glycine amidinotransferase (L-arginine:glycine amidinotransferase) response to mercury ion Biological process - NOTUM 147111 notum pectinacetylesterase homolog (Drosophila) extracellular region Cellular component - HDAC6 10013 histone deacetylase 6 response to misfolded protein Biological process 14675537 CERS3 204219 ceramide synthase 3 sphingosine N-acyltransferase activity Molecular function - IGFBP5 3488 insulin-like growth factor binding protein 5 cellular response to cAMP Biological process 7559606 ERVFRD-1 405754 endogenous retrovirus group FRD, member 1 syncytium formation Biological process 23492904 BFSP1 631 beaded filament structural protein 1, filensin cytoplasm Cellular component - CACNB2 783 calcium channel, voltage-dependent, beta 2 subunit axon guidance Biological process - SLC12A2 6558 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 transepithelial chloride transport Biological process 12946942 HSP90B1 7184 heat shock protein 90kDa beta (Grp94), member 1 protein phosphatase binding Molecular function 19000834 VTI1A 143187 vesicle transport through interaction with t-SNAREs 1A Golgi apparatus Cellular component 19224922 MRGBP 55257 MRG/MORF4L binding protein H4/H2A histone acetyltransferase complex Cellular component - SULT1B1 27284 sulfotransferase family, cytosolic, 1B, member 1 aryl sulfotransferase activity Molecular function - ZMYND8 23613 zinc finger, MYND-type containing 8 RNA polymerase II transcription corepressor activity Molecular function - RAP1GAP 5909 RAP1 GTPase activating protein cytosol Cellular component - LRG1 116844 leucine-rich alpha-2-glycoprotein 1 extracellular exosome Cellular component 23376485 SLC15A3 51296 solute carrier family 15 (oligopeptide transporter), member 3 intracellular membrane-bounded organelle Cellular component - NLGN4X 57502 neuroligin 4, X-linked dendrite Cellular component 19726642 TET3 200424 tet methylcytosine dioxygenase 3 gene expression Biological process - SLC17A8 246213 solute carrier family 17 (vesicular glutamate transporter), member 8 ion transport Biological process - ZFYVE9 9372 zinc finger, FYVE domain containing 9 protein binding Molecular function 12154125 NGF 4803 nerve growth factor (beta polypeptide) extrinsic apoptotic signaling pathway in absence of ligand Biological process - UBE2B 7320 ubiquitin-conjugating enzyme E2B response to UV Biological process 1717990 NUP160 23279 nucleoporin 160kDa viral transcription Biological process - ZYX 7791 zyxin focal adhesion Cellular component - EYS 346007 eyes shut homolog (Drosophila) detection of light stimulus involved in visual perception Biological process 18836446 NF2 4771 neurofibromin 2 (merlin) negative regulation of MAPK cascade Biological process - PDX1 3651 pancreatic and duodenal homeobox 1 positive regulation of cell proliferation Biological process - TIMM50 92609 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) protein targeting to mitochondrion Biological process - ZNF540 163255 zinc finger protein 540 nucleoplasm Cellular component - KRR1 11103 KRR1, small subunit (SSU) processome component, homolog (yeast) nucleolus Cellular component - KLF1 10661 Kruppel-like factor 1 (erythroid) embryonic hemopoiesis Biological process - HYPK 25764 huntingtin interacting protein K nucleus Cellular component - SERBP1 26135 SERPINE1 mRNA binding protein 1 regulation of mRNA stability Biological process 11001948 PRKAA2 5563 protein kinase, AMP-activated, alpha 2 catalytic subunit negative regulation of TOR signaling Biological process - OR4C5 79346 olfactory receptor, family 4, subfamily C, member 5 (gene/pseudogene) detection of chemical stimulus involved in sensory perception of smell Biological process - BARX1 56033 BARX homeobox 1 digestive system development Biological process - NUTF2 10204 nuclear transport factor 2 protein import into nucleus, translocation Biological process 18266911 FAM160A2 84067 family with sequence similarity 160, member A2 endosome organization Biological process 18799622 APOA1BP 128240 apolipoprotein A-I binding protein protein homodimerization activity Molecular function - IRAK2 3656 interleukin-1 receptor-associated kinase 2 toll-like receptor 4 signaling pathway Biological process - STATH 6779 statherin saliva secretion Biological process 1718282 CSNK2A1 1457 casein kinase 2, alpha 1 polypeptide Sin3 complex Cellular component 17827154 GTF2F1 2962 general transcription factor IIF, polypeptide 1, 74kDa phosphatase activator activity Molecular function 12721286 GLCE 26035 glucuronic acid epimerase glycosaminoglycan metabolic process Biological process - ZNF582 147948 zinc finger protein 582 regulation of transcription, DNA-templated Biological process - BMPR1B 658 bone morphogenetic protein receptor, type IB transforming growth factor beta receptor activity, type I Molecular function - POSTN 10631 periostin, osteoblast specific factor heparin binding Molecular function - MVK 4598 mevalonate kinase ATP binding Molecular function - MRPL1 65008 mitochondrial ribosomal protein L1 protein binding Molecular function 25416956 CLEC4M 10332 C-type lectin domain family 4, member M membrane Cellular component 11337487 TPPP3 51673 tubulin polymerization-promoting protein family member 3 microtubule Cellular component - BANP 54971 BTG3 associated nuclear protein negative regulation of protein catabolic process Biological process - HDDC3 374659 HD domain containing 3 protein binding Molecular function 16189514 S100A8 6279 S100 calcium binding protein A8 sequestering of zinc ion Biological process 22489132 ADAMTSL1 92949 ADAMTS-like 1 endoplasmic reticulum lumen Cellular component - MERTK 10461 MER proto-oncogene, tyrosine kinase natural killer cell differentiation Biological process - MESP2 145873 mesoderm posterior basic helix-loop-helix transcription factor 2 mesodermal cell migration Biological process - ZFY 7544 zinc finger protein, Y-linked DNA binding Molecular function - SCN5A 6331 sodium channel, voltage gated, type V alpha subunit positive regulation of epithelial cell proliferation Biological process - MAEL 84944 maelstrom spermatogenic transposon silencer autosome Cellular component - RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region positive regulation of ephrin receptor signaling pathway Biological process - ZFPM1 161882 zinc finger protein, FOG family member 1 cardiac muscle tissue morphogenesis Biological process - PTGIS 5740 prostaglandin I2 (prostacyclin) synthase NAD metabolic process Biological process - SASH1 23328 SAM and SH3 domain containing 1 positive regulation of p38MAPK cascade Biological process 23776175 LCAT 3931 lecithin-cholesterol acyltransferase phosphatidylcholine-sterol O-acyltransferase activity Molecular function 11966470 B4GAT1 11041 beta-1,4-glucuronyltransferase 1 Golgi membrane Cellular component - MUCL1 118430 mucin-like 1 post-translational protein modification Biological process - MPP7 143098 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) protein domain specific binding Molecular function 17332497 KCNG3 170850 potassium channel, voltage gated modifier subfamily G, member 3 voltage-gated potassium channel complex Cellular component 19074135 GSK3B 2932 glycogen synthase kinase 3 beta response to lithium ion Biological process - HSD3B1 3283 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 endoplasmic reticulum membrane Cellular component - PSMC3 5702 proteasome (prosome, macropain) 26S subunit, ATPase, 3 nucleus Cellular component 21630459 TAB2 23118 TGF-beta activated kinase 1/MAP3K7 binding protein 2 plasma membrane Cellular component - RAC3 5881 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) neuron projection development Biological process - BCL2L1 598 BCL2-like 1 growth Biological process - HOXA13 3209 homeobox A13 vasculogenesis Biological process - BEX1 55859 brain expressed, X-linked 1 RNA polymerase II activating transcription factor binding Molecular function 16314316 NCSTN 23385 nicastrin protein binding Molecular function 12297508 GPR149 344758 G protein-coupled receptor 149 antral ovarian follicle growth Biological process - METTL1 4234 methyltransferase like 1 tRNA binding Molecular function - PARK7 11315 parkinson protein 7 protein binding Molecular function 11477070 NME1 4830 NME/NM23 nucleoside diphosphate kinase 1 ruffle membrane Cellular component 16814409 TAZ 6901 tafazzin hemopoiesis Biological process 17043667 COL13A1 1305 collagen, type XIII, alpha 1 endoplasmic reticulum lumen Cellular component - PEX3 8504 peroxisomal biogenesis factor 3 peroxisome membrane biogenesis Biological process - PGLYRP3 114771 peptidoglycan recognition protein 3 extracellular region Cellular component - PRDM2 7799 PR domain containing 2, with ZNF domain regulation of transcription, DNA-templated Biological process 7590293 SPA17 53340 sperm autoantigenic protein 17 binding of sperm to zona pellucida Biological process - MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase negative regulation of cell cycle arrest Biological process 9529249 TBP 6908 TATA box binding protein transcription initiation from RNA polymerase I promoter Biological process - SLC6A16 28968 solute carrier family 6, member 16 transmembrane transport Biological process - WNT2B 7482 wingless-type MMTV integration site family, member 2B neuron differentiation Biological process - NECAP2 55707 NECAP endocytosis associated 2 protein transport Biological process - RBBP7 5931 retinoblastoma binding protein 7 transcription, DNA-templated Biological process - INPP5D 3635 inositol polyphosphate-5-phosphatase, 145kDa positive regulation of B cell differentiation Biological process - CD34 947 CD34 molecule endothelial cell proliferation Biological process 21835908 PGK1 5230 phosphoglycerate kinase 1 phosphoglycerate kinase activity Molecular function - ANAPC13 25847 anaphase promoting complex subunit 13 protein K11-linked ubiquitination Biological process 18485873 S1PR3 1903 sphingosine-1-phosphate receptor 3 regulation of interleukin-1 beta production Biological process - IDUA 3425 iduronidase, alpha-L- chondroitin sulfate catabolic process Biological process - PDIA5 10954 protein disulfide isomerase family A, member 5 protein disulfide isomerase activity Molecular function 7556671 WDPCP 51057 WD repeat containing planar cell polarity effector camera-type eye development Biological process - MSMO1 6307 methylsterol monooxygenase 1 steroid metabolic process Biological process 8663358 RIPPLY1 92129 ripply transcriptional repressor 1 protein binding Molecular function 25416956 MED16 10025 mediator complex subunit 16 receptor activity Molecular function 12218053 INPPL1 3636 inositol polyphosphate phosphatase-like 1 actin binding Molecular function - CD36 948 CD36 molecule (thrombospondin receptor) receptor-mediated endocytosis Biological process - CTNNA1 1495 catenin (cadherin-associated protein), alpha 1, 102kDa negative regulation of neuroblast proliferation Biological process - AGPAT2 10555 1-acylglycerol-3-phosphate O-acyltransferase 2 positive regulation of cytokine-mediated signaling pathway Biological process 9212163 CCK 885 cholecystokinin protein kinase C-activating G-protein coupled receptor signaling pathway Biological process - SKIL 6498 SKI-like proto-oncogene protein heterotrimerization Biological process 8514802 PDGFRB 5159 platelet-derived growth factor receptor, beta polypeptide neurotrophin TRK receptor signaling pathway Biological process - IL36G 56300 interleukin 36, gamma negative regulation of myoblast differentiation Biological process - SCNN1G 6340 sodium channel, non voltage gated 1 gamma subunit multicellular organismal water homeostasis Biological process 24124190 E2F3 1871 E2F transcription factor 3 nucleoplasm Cellular component - HES5 388585 hes family bHLH transcription factor 5 neuronal stem cell maintenance Biological process 19682396 BHLHE41 79365 basic helix-loop-helix family, member e41 negative regulation of transcription from RNA polymerase II promoter Biological process 14672706 TACR1 6869 tachykinin receptor 1 positive regulation of saliva secretion Biological process - DLG1 1739 discs, large homolog 1 (Drosophila) immunological synapse Cellular component 19841189 DHCR24 1718 24-dehydrocholesterol reductase response to hormone Biological process - TNNC2 7125 troponin C type 2 (fast) regulation of muscle contraction Biological process 2373703 TLR2 7097 toll-like receptor 2 I-kappaB phosphorylation Biological process 19740627 MATK 4145 megakaryocyte-associated tyrosine kinase non-membrane spanning protein tyrosine kinase activity Molecular function - DUSP12 11266 dual specificity phosphatase 12 protein tyrosine phosphatase activity Molecular function - PHF8 23133 PHD finger protein 8 histone demethylase activity Molecular function 19843542 RSC1A1 6248 regulatory solute carrier protein, family 1, member 1 regulation of transcription, DNA-templated Biological process - ME3 10873 malic enzyme 3, NADP(+)-dependent, mitochondrial oxaloacetate decarboxylase activity Molecular function - PNLIPRP2 5408 pancreatic lipase-related protein 2 phospholipid catabolic process Biological process 18702514 NR1D2 9975 nuclear receptor subfamily 1, group D, member 2 positive regulation of transcription, DNA-templated Biological process - CLEC4M 10332 C-type lectin domain family 4, member M virus receptor activity Molecular function 15496474 SEC16B 89866 SEC16 homolog B (S. cerevisiae) endoplasmic reticulum organization Biological process 21768384 ATP4A 495 ATPase, H+/K+ exchanging, alpha polypeptide sodium:potassium-exchanging ATPase activity Molecular function - HMGCL 3155 3-hydroxymethyl-3-methylglutaryl-CoA lyase small molecule metabolic process Biological process - SNX8 29886 sorting nexin 8 endosome Cellular component - AK9 221264 adenylate kinase 9 ATP binding Molecular function - EPHB6 2051 EPH receptor B6 ephrin receptor activity Molecular function - SKOR1 390598 SKI family transcriptional corepressor 1 neuronal cell body Cellular component 17292623 IFT20 90410 intraflagellar transport 20 regulation of canonical Wnt signaling pathway Biological process - DDX51 317781 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 ATP binding Molecular function - RNF157 114804 ring finger protein 157 zinc ion binding Molecular function - DICER1 23405 dicer 1, ribonuclease type III RNA phosphodiester bond hydrolysis, endonucleolytic Biological process 21753850 GABRQ 55879 gamma-aminobutyric acid (GABA) A receptor, theta GABA-A receptor activity Molecular function - OR1F12 442179 olfactory receptor, family 1, subfamily F, member 12 plasma membrane Cellular component - MRPL23 6150 mitochondrial ribosomal protein L23 mitochondrial translational initiation Biological process - ACP2 53 acid phosphatase 2, lysosomal acid phosphatase activity Molecular function - KRTAP1-4 728255 keratin associated protein 1-4 keratin filament Cellular component - HSPB1 3315 heat shock 27kDa protein 1 protein kinase C inhibitor activity Molecular function - AVPR1B 553 arginine vasopressin receptor 1B cellular response to hormone stimulus Biological process - DDX54 79039 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 nucleus Cellular component 12466272 TK2 7084 thymidine kinase 2, mitochondrial deoxycytidine metabolic process Biological process - TESC 54997 tescalcin negative regulation of protein kinase activity Biological process - LRTOMT 220074 leucine rich transmembrane and O-methyltransferase domain containing sensory perception of sound Biological process 18794526 TLN2 83660 talin 2 protein binding Molecular function 10320934 PAK2 5062 p21 protein (Cdc42/Rac)-activated kinase 2 regulation of MAPK cascade Biological process - EXOC4 60412 exocyst complex component 4 protein transport Biological process - WTIP 126374 Wilms tumor 1 interacting protein adherens junction Cellular component - VCAN 1462 versican osteoblast differentiation Biological process 16210410 HYAL2 8692 hyaluronoglucosaminidase 2 anchored component of external side of plasma membrane Cellular component 19443707 C16orf54 283897 chromosome 16 open reading frame 54 integral component of membrane Cellular component - BYSL 705 bystin-like trophectodermal cell differentiation Biological process - NGDN 25983 neuroguidin, EIF4E binding protein cytoplasm Cellular component - ADAT1 23536 adenosine deaminase, tRNA-specific 1 metal ion binding Molecular function - GGN 199720 gametogenetin protein dimerization activity Molecular function - PRSS8 5652 protease, serine, 8 extracellular region Cellular component 10077646 UROD 7389 uroporphyrinogen decarboxylase protein binding Molecular function 25416956 MSH4 4438 mutS homolog 4 meiotic mismatch repair Biological process - PEG3 5178 paternally expressed 3 genetic imprinting Biological process - VAMP3 9341 vesicle-associated membrane protein 3 cytosol Cellular component 22589474 MAN2B1 4125 mannosidase, alpha, class 2B, member 1 extracellular exosome Cellular component 23376485 C19orf80 55908 chromosome 19 open reading frame 80 type B pancreatic cell proliferation Biological process - OAZ1 4946 ornithine decarboxylase antizyme 1 regulation of cellular amino acid metabolic process Biological process - GLIPR1 11010 GLI pathogenesis-related 1 plasma membrane Cellular component - TFRC 7037 transferrin receptor perinuclear region of cytoplasm Cellular component 20202662 LAMB1 3912 laminin, beta 1 extracellular matrix organization Biological process - ICAM1 3383 intercellular adhesion molecule 1 response to ethanol Biological process - LRRC7 57554 leucine rich repeat containing 7 cell junction Cellular component - ANKRD42 338699 ankyrin repeat domain 42 positive regulation of NF-kappaB transcription factor activity Biological process - NOS1 4842 nitric oxide synthase 1 (neuronal) ion channel binding Molecular function 21536106 MYO5A 4644 myosin VA (heavy chain 12, myoxin) late endosome Cellular component 24006491 CYFIP2 26999 cytoplasmic FMR1 interacting protein 2 protein binding Molecular function 11438699 SLC24A2 25769 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 learning Biological process - SIRT2 22933 sirtuin 2 cellular lipid catabolic process Biological process - MAD1L1 8379 MAD1 mitotic arrest deficient-like 1 (yeast) cell division Biological process - MZT2A 653784 mitotic spindle organizing protein 2A gamma-tubulin ring complex Cellular component - ACKR1 2532 atypical chemokine receptor 1 (Duffy blood group) defense response Biological process 10570183 SIN3A 25942 SIN3 transcription regulator family member A nucleolus Cellular component - TAS2R45 259291 taste receptor, type 2, member 45 plasma membrane Cellular component - EDA 1896 ectodysplasin A cell differentiation Biological process - CDCA8 55143 cell division cycle associated 8 midbody Cellular component 22724069 MME 4311 membrane metallo-endopeptidase protein binding Molecular function 17342744 MYCBP2 23077 MYC binding protein 2, E3 ubiquitin protein ligase regulation of protein localization Biological process - GAS1 2619 growth arrest-specific 1 embryonic digit morphogenesis Biological process - RPGRIP1L 23322 RPGRIP1-like cilium assembly Biological process - GABRR1 2569 gamma-aminobutyric acid (GABA) A receptor, rho 1 cell junction Cellular component - RAD23B 5887 RAD23 homolog B (S. cerevisiae) cytoplasm Cellular component - FH 2271 fumarate hydratase mitochondrion Cellular component - SMARCD3 6604 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 regulation of protein binding Biological process - HIPK2 28996 homeodomain interacting protein kinase 2 nucleus Cellular component - DNAJA4 55466 DnaJ (Hsp40) homolog, subfamily A, member 4 unfolded protein binding Molecular function 21231916 PPBP 5473 pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) glucose transport Biological process 4005226 DDX41 51428 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 mRNA splicing, via spliceosome Biological process 11991638 STRADB 55437 STE20-related kinase adaptor beta insulin receptor signaling pathway Biological process - GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A neuronal postsynaptic density Cellular component - TCOF1 6949 Treacher Collins-Franceschetti syndrome 1 nucleolus Cellular component - CLCN4 1183 chloride channel, voltage-sensitive 4 antiporter activity Molecular function - CBLN1 869 cerebellin 1 precursor protein homodimerization activity Molecular function - SMIM3 85027 small integral membrane protein 3 protein binding Molecular function 16189514 CD4 920 CD4 molecule protein homodimerization activity Molecular function 12444132 VCPIP1 80124 valosin containing protein (p97)/p47 complex interacting protein 1 protein K48-linked deubiquitination Biological process 23827681 PRKCG 5582 protein kinase C, gamma cytosol Cellular component - TNKS 8658 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase NAD+ ADP-ribosyltransferase activity Molecular function - SERPINF1 5176 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 perinuclear region of cytoplasm Cellular component - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa lateral plasma membrane Cellular component 12072559 FOXO6 100132074 forkhead box O6 anatomical structure morphogenesis Biological process - HDAC2 3066 histone deacetylase 2 ESC/E(Z) complex Cellular component 20075857 MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase cellular response to vitamin B1 Biological process - RILP 83547 Rab interacting lysosomal protein endosome transport via multivesicular body sorting pathway Biological process 17010938 PSMD13 5719 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process Biological process - PRIMPOL 201973 primase and polymerase (DNA-directed) response to UV Biological process 24240614 P2RX6 9127 purinergic receptor P2X, ligand gated ion channel, 6 channel activity Molecular function 9242461 WBP11 51729 WW domain binding protein 11 rRNA processing Biological process - ING4 51147 inhibitor of growth family, member 4 protein binding Molecular function 12750254 SIAH2 6478 siah E3 ubiquitin protein ligase 2 protein ubiquitination Biological process - ERCC5 2073 excision repair cross-complementation group 5 response to UV Biological process 16167068 GABARAP 11337 GABA(A) receptor-associated protein cell body Cellular component - LONRF2 164832 LON peptidase N-terminal domain and ring finger 2 zinc ion binding Molecular function - GGTLC2 91227 gamma-glutamyltransferase light chain 2 gamma-glutamyltransferase activity Molecular function 18357469 KLF4 9314 Kruppel-like factor 4 (gut) negative regulation of response to cytokine stimulus Biological process 20551324 IFIT2 3433 interferon-induced protein with tetratricopeptide repeats 2 poly(A) RNA binding Molecular function 22658674 PECAM1 5175 platelet/endothelial cell adhesion molecule 1 extracellular exosome Cellular component 20458337 GEN1 348654 GEN1 Holliday junction 5' flap endonuclease regulation of centrosome duplication Biological process 23108668 OLFML1 283298 olfactomedin-like 1 extracellular region Cellular component - PSMD2 5708 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 cellular nitrogen compound metabolic process Biological process - CHST15 51363 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 glycosaminoglycan metabolic process Biological process - UCP3 7352 uncoupling protein 3 (mitochondrial, proton carrier) proton transport Biological process - FASLG 356 Fas ligand (TNF superfamily, member 6) regulation of extrinsic apoptotic signaling pathway via death domain receptors Biological process - NHLRC1 378884 NHL repeat containing E3 ubiquitin protein ligase 1 autophagy Biological process - SRF 6722 serum response factor (c-fos serum response element-binding transcription factor) response to toxic substance Biological process 12660819 ITCH 83737 itchy E3 ubiquitin protein ligase ubiquitin-protein transferase activity Molecular function - GGT1 2678 gamma-glutamyltransferase 1 anchored component of external side of plasma membrane Cellular component 18357469 CHRNA1 1134 cholinergic receptor, nicotinic, alpha 1 (muscle) cell junction Cellular component - TGOLN2 10618 trans-golgi network protein 2 Golgi apparatus Cellular component - PAF1 54623 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) chromatin binding Molecular function - YLPM1 56252 YLP motif containing 1 nuclear speck Cellular component - GARNL3 84253 GTPase activating Rap/RanGAP domain-like 3 GTPase activator activity Molecular function - SPRR2D 6703 small proline-rich protein 2D epidermis development Biological process 8325635 SLC18A2 6571 solute carrier family 18 (vesicular monoamine transporter), member 2 response to zinc ion Biological process - ATP1A3 478 ATPase, Na+/K+ transporting, alpha 3 polypeptide nucleus Cellular component - NODAL 4838 nodal growth differentiation factor negative regulation of trophoblast cell migration Biological process 21356369 BRAF 673 B-Raf proto-oncogene, serine/threonine kinase glucose transport Biological process 23010278 SSTR3 6753 somatostatin receptor 3 somatostatin receptor activity Molecular function - GPT2 84706 glutamic pyruvate transaminase (alanine aminotransferase) 2 cellular nitrogen compound metabolic process Biological process - MAST4 375449 microtubule associated serine/threonine kinase family member 4 magnesium ion binding Molecular function - NRXN3 9369 neurexin 3 learning Biological process 22209245 HTR4 3360 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled cytoplasm Cellular component 15925089 GABARAPL1 23710 GABA(A) receptor-associated protein like 1 pre-autophagosomal structure Cellular component - NTRK3 4916 neurotrophic tyrosine kinase, receptor, type 3 response to corticosterone Biological process - CACTIN 58509 cactin, spliceosome C complex subunit cellular response to interleukin-1 Biological process 20829348 JAZF1 221895 JAZF zinc finger 1 nucleus Cellular component - SHROOM2 357 shroom family member 2 cytoskeleton Cellular component - OR51E1 143503 olfactory receptor, family 51, subfamily E, member 1 integral component of membrane Cellular component - XPNPEP1 7511 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble protein homodimerization activity Molecular function 18515364 PCDH12 51294 protocadherin 12 extracellular exosome Cellular component 23376485 SLC3A2 6520 solute carrier family 3 (amino acid transporter heavy chain), member 2 melanosome Cellular component - IST1 9798 increased sodium tolerance 1 homolog (yeast) positive regulation of defense response to virus by host Biological process 22020285 MAN2A2 4122 mannosidase, alpha, class 2A, member 2 Golgi membrane Cellular component - PIP4K2B 8396 phosphatidylinositol-5-phosphate 4-kinase, type II, beta cell surface receptor signaling pathway Biological process 9038203 OR13C9 286362 olfactory receptor, family 13, subfamily C, member 9 detection of chemical stimulus involved in sensory perception of smell Biological process - CENPT 80152 centromere protein T protein heterodimerization activity Molecular function - RPS27A 6233 ribosomal protein S27a positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Biological process - CCSAP 126731 centriole, cilia and spindle-associated protein regulation of embryonic development Biological process - ELOVL6 79071 ELOVL fatty acid elongase 6 protein binding Molecular function 20937905 CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 epoxygenase P450 pathway Biological process - NOTCH1 4851 notch 1 chromatin DNA binding Molecular function - PDPK1 5170 3-phosphoinositide dependent protein kinase 1 blood coagulation Biological process - RBMS1 5937 RNA binding motif, single stranded interacting protein 1 RNA binding Molecular function 8041632 PSPN 5623 persephin branching involved in ureteric bud morphogenesis Biological process - STAB2 55576 stabilin 2 hyaluronan metabolic process Biological process - PRDX4 10549 peroxiredoxin 4 oxidation-reduction process Biological process - EVC2 132884 Ellis van Creveld syndrome 2 nucleus Cellular component - TRUB1 142940 TruB pseudouridine (psi) synthase family member 1 mRNA pseudouridine synthesis Biological process - CHST8 64377 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 Golgi membrane Cellular component - HDC 3067 histidine decarboxylase protein binding Molecular function 25416956 DNAJA3 9093 DnaJ (Hsp40) homolog, subfamily A, member 3 negative regulation of interferon-gamma-mediated signaling pathway Biological process 11679576 LIG4 3981 ligase IV, DNA, ATP-dependent cell proliferation Biological process - OR2A25 392138 olfactory receptor, family 2, subfamily A, member 25 plasma membrane Cellular component - CLEC4C 170482 C-type lectin domain family 4, member C plasma membrane Cellular component - CRYBA2 1412 crystallin, beta A2 molecular_function Molecular function - ARRDC3 57561 arrestin domain containing 3 fat pad development Biological process - ABCA11P 79963 ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene ATPase activity Molecular function - RAB7B 338382 RAB7B, member RAS oncogene family positive regulation of interleukin-6 production Biological process 20953574 SON 6651 SON DNA binding protein mRNA processing Biological process 21504830 NUP98 4928 nucleoporin 98kDa nuclear membrane Cellular component 11839768 CNEP1R1 255919 CTD nuclear envelope phosphatase 1 regulatory subunit 1 positive regulation of protein dephosphorylation Biological process 22134922 TSPAN9 10867 tetraspanin 9 integral component of membrane Cellular component - FBXO7 25793 F-box protein 7 ubiquitin-dependent protein catabolic process Biological process 10531035 HNRNPUL2 221092 heterogeneous nuclear ribonucleoprotein U-like 2 nucleus Cellular component - EXOSC3 51010 exosome component 3 isotype switching Biological process - PLEKHG5 57449 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 endothelial cell chemotaxis Biological process - GABRA5 2558 gamma-aminobutyric acid (GABA) A receptor, alpha 5 transport Biological process 1321750 SPATA25 128497 spermatogenesis associated 25 spermatogenesis Biological process 19240080 GPX1 2876 glutathione peroxidase 1 hydrogen peroxide catabolic process Biological process 15203190 KIF3B 9371 kinesin family member 3B midbody Cellular component - NPY5R 4889 neuropeptide Y receptor Y5 pancreatic polypeptide receptor activity Molecular function - SYT3 84258 synaptotagmin III plasma membrane Cellular component - IL18RAP 8807 interleukin 18 receptor accessory protein receptor activity Molecular function 9792649 GDF11 10220 growth differentiation factor 11 extracellular space Cellular component - NDUFA5 4698 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 respiratory electron transport chain Biological process - RHEBL1 121268 Ras homolog enriched in brain like 1 endomembrane system Cellular component - POLB 5423 polymerase (DNA directed), beta pyrimidine dimer repair Biological process - TLR2 7097 toll-like receptor 2 triacyl lipopeptide binding Molecular function 17889651 CACNA1C 775 calcium channel, voltage-dependent, L type, alpha 1C subunit integral component of membrane Cellular component 8392192 LRP6 4040 low density lipoprotein receptor-related protein 6 embryonic hindlimb morphogenesis Biological process - RPP40 10799 ribonuclease P/MRP 40kDa subunit tRNA processing Biological process - PRDM1 639 PR domain containing 1, with ZNF domain RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function 1851123 GLI3 2737 GLI family zinc finger 3 palate development Biological process - CDH1 999 cadherin 1, type 1, E-cadherin (epithelial) protein phosphatase binding Molecular function - VCP 7415 valosin containing protein ER-associated misfolded protein catabolic process Biological process 24089527 MTERF4 130916 mitochondrial transcription termination factor 4 double-stranded DNA binding Molecular function - EDA 1896 ectodysplasin A salivary gland cavitation Biological process - DUSP6 1848 dual specificity phosphatase 6 cell differentiation Biological process - HTRA2 27429 HtrA serine peptidase 2 protein autoprocessing Biological process 11602612 POLDIP3 84271 polymerase (DNA-directed), delta interacting protein 3 exon-exon junction complex Cellular component 18423201 NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 intracellular signal transduction Biological process 14749367 PITX2 5308 paired-like homeodomain 2 sequence-specific DNA binding transcription factor activity Molecular function 11301317 KIF24 347240 kinesin family member 24 kinesin complex Cellular component - SCN3B 55800 sodium channel, voltage gated, type III beta subunit cardiac muscle contraction Biological process 20042427 AGO4 192670 argonaute RISC catalytic component 4 double-stranded RNA binding Molecular function 19966796 RASL11A 387496 RAS-like, family 11, member A positive regulation of transcription from RNA polymerase I promoter Biological process - CA4 762 carbonic anhydrase IV brush border membrane Cellular component 17409381 ARHGEF4 50649 Rho guanine nucleotide exchange factor (GEF) 4 ruffle membrane Cellular component - CXCR2 3579 chemokine (C-X-C motif) receptor 2 chemokine-mediated signaling pathway Biological process - ING4 51147 inhibitor of growth family, member 4 apoptotic process Biological process 15251430 TMEM204 79652 transmembrane protein 204 regulation of vascular endothelial growth factor receptor signaling pathway Biological process - SPON1 10418 spondin 1, extracellular matrix protein post-translational protein modification Biological process - STAG2 10735 stromal antigen 2 stem cell maintenance Biological process - SIX3 6496 SIX homeobox 3 regulation of neural retina development Biological process - CDC6 990 cell division cycle 6 cytosol Cellular component - TCP11 6954 t-complex 11, testis-specific multicellular organismal development Biological process 1893875 CDK2 1017 cyclin-dependent kinase 2 cytoplasm Cellular component 10767298 KPTN 11133 kaptin (actin binding protein) microtubule organizing center Cellular component 1372044 ELANE 1991 elastase, neutrophil expressed response to yeast Biological process - BSN 8927 bassoon presynaptic cytomatrix protein synapse assembly Biological process - STK11 6794 serine/threonine kinase 11 small molecule metabolic process Biological process - MFI2 4241 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 extracellular exosome Cellular component 19056867 EIF2B5 8893 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa oligodendrocyte development Biological process 15217090 COPG1 22820 coatomer protein complex, subunit gamma 1 retrograde vesicle-mediated transport, Golgi to ER Biological process - CHGB 1114 chromogranin B extracellular region Cellular component - CTGF 1490 connective tissue growth factor response to amino acid Biological process - CRHBP 1393 corticotropin releasing hormone binding protein regulation of corticotropin secretion Biological process 13150566 CACNA1A 773 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit integral component of membrane Cellular component 16595610 MEGF8 1954 multiple EGF-like-domains 8 calcium ion binding Molecular function - TRPM4 54795 transient receptor potential cation channel, subfamily M, member 4 Golgi apparatus Cellular component 19945433 CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha liver development Biological process - BPI 671 bactericidal/permeability-increasing protein extracellular exosome Cellular component 19056867 OCLN 100506658 occludin cytosol Cellular component - HNRNPA2B1 3181 heterogeneous nuclear ribonucleoprotein A2/B1 mRNA processing Biological process 2557628 MEIOB 254528 meiosis specific with OB domains double-strand break repair via homologous recombination Biological process - FFAR3 2865 free fatty acid receptor 3 positive regulation of glucose import in response to insulin stimulus Biological process - ZC3H12B 340554 zinc finger CCCH-type containing 12B nucleic acid phosphodiester bond hydrolysis Biological process - MDFIC 29969 MyoD family inhibitor domain containing negative regulation of transcription, DNA-templated Biological process - DEFB132 400830 defensin, beta 132 extracellular region Cellular component - HDAC7 51564 histone deacetylase 7 positive regulation of cell migration involved in sprouting angiogenesis Biological process 19351956 PDPK1 5170 3-phosphoinositide dependent protein kinase 1 intracellular signal transduction Biological process 14749367 EAF2 55840 ELL associated factor 2 RNA polymerase II regulatory region sequence-specific DNA binding Molecular function 16114057 CFB 629 complement factor B plasma membrane Cellular component - NOTCH4 4855 notch 4 cell fate determination Biological process 11823422 HRH1 3269 histamine receptor H1 cellular response to histamine Biological process - CYP1A1 1543 cytochrome P450, family 1, subfamily A, polypeptide 1 response to hyperoxia Biological process - TRIM15 89870 tripartite motif containing 15 protein binding Molecular function 25416956 RAD17 5884 RAD17 homolog (S. pombe) Rad17 RFC-like complex Cellular component - VAMP5 10791 vesicle-associated membrane protein 5 integral component of plasma membrane Cellular component - ANK3 288 ankyrin 3, node of Ranvier (ankyrin G) postsynaptic membrane Cellular component - SMAD2 4087 SMAD family member 2 SMAD protein signal transduction Biological process - ACAA1 30 acetyl-CoA acyltransferase 1 fatty acid beta-oxidation Biological process 2365812 CLGN 1047 calmegin integral component of membrane Cellular component - EPS15 2060 epidermal growth factor receptor pathway substrate 15 plasma membrane Cellular component 15465819 ALOX12 239 arachidonate 12-lipoxygenase positive regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process - CHRM3 1131 cholinergic receptor, muscarinic 3 axon terminus Cellular component - CCNC 892 cyclin C regulation of cyclin-dependent protein serine/threonine kinase activity Biological process - SOX17 64321 SRY (sex determining region Y)-box 17 cell migration involved in gastrulation Biological process - KIF18A 81930 kinesin family member 18A tubulin-dependent ATPase activity Molecular function 17346968 PAK2 5062 p21 protein (Cdc42/Rac)-activated kinase 2 protein serine/threonine kinase activity Molecular function - THTPA 79178 thiamine triphosphatase cytosol Cellular component - C5 727 complement component 5 extracellular region Cellular component - CENPA 1058 centromere protein A condensed nuclear chromosome, centromeric region Cellular component 11682612 MIER1 57708 mesoderm induction early response 1, transcriptional regulator chromatin binding Molecular function - MPPED1 758 metallophosphoesterase domain containing 1 hydrolase activity Molecular function - NDP 4693 Norrie disease (pseudoglioma) extracellular matrix-cell signaling Biological process - PIK3C3 5289 phosphatidylinositol 3-kinase, catalytic subunit type 3 late endosome Cellular component 14617358 RNF139 11236 ring finger protein 139 receptor activity Molecular function 9689122 AQP11 282679 aquaporin 11 cytosol Cellular component - SLIT2 9353 slit homolog 2 (Drosophila) induction of negative chemotaxis Biological process 10197527 POP4 10775 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) ribonuclease P complex Cellular component - CD109 135228 CD109 molecule negative regulation of protein phosphorylation Biological process - NRAS 4893 neuroblastoma RAS viral (v-ras) oncogene homolog epidermal growth factor receptor signaling pathway Biological process - BLM 641 Bloom syndrome, RecQ helicase-like protein oligomerization Biological process 10359700 AXIN2 8313 axin 2 cytosol Cellular component - ERCC2 2068 excision repair cross-complementation group 2 gene expression Biological process - PDE1B 5153 phosphodiesterase 1B, calmodulin-dependent fibroblast growth factor receptor signaling pathway Biological process - FBXL15 79176 F-box and leucine-rich repeat protein 15 G2/M transition of mitotic cell cycle Biological process 21572392 NLRX1 79671 NLR family member X1 protein binding Molecular function 21903422 ZNF441 126068 zinc finger protein 441 regulation of transcription, DNA-templated Biological process - ZNF45 7596 zinc finger protein 45 nucleoplasm Cellular component - ECM2 1842 extracellular matrix protein 2, female organ and adipocyte specific collagen V binding Molecular function - TNFRSF9 3604 tumor necrosis factor receptor superfamily, member 9 receptor activity Molecular function - IRG1 730249 immunoresponsive 1 homolog (mouse) negative regulation of innate immune response Biological process - TMEM98 26022 transmembrane protein 98 integral component of membrane Cellular component - OCSTAMP 128506 osteoclast stimulatory transmembrane protein cellular response to tumor necrosis factor Biological process - ZNF343 79175 zinc finger protein 343 regulation of transcription, DNA-templated Biological process - SYT11 23208 synaptotagmin XI synaptic vesicle Cellular component 21563316 TTC8 123016 tetratricopeptide repeat domain 8 ciliary basal body Cellular component 14520415 MATN2 4147 matrilin 2 basement membrane Cellular component - C1QTNF1 114897 C1q and tumor necrosis factor related protein 1 protein heterotrimerization Biological process - ZNF283 284349 zinc finger protein 283 sequence-specific DNA binding transcription factor activity Molecular function - ADK 132 adenosine kinase purine nucleobase metabolic process Biological process - PAPD5 64282 PAP associated domain containing 5 cell division Biological process - ZNF148 7707 zinc finger protein 148 negative regulation of transcription from RNA polymerase II promoter Biological process 12771217 RNASEH2A 10535 ribonuclease H2, subunit A RNA phosphodiester bond hydrolysis Biological process 9789007 DOCK10 55619 dedicator of cytokinesis 10 small GTPase mediated signal transduction Biological process - HIST1H4H 8365 histone cluster 1, H4h extracellular exosome Cellular component 19199708 TXN 7295 thioredoxin movement of cell or subcellular component Biological process 10947064 LIMK1 3984 LIM domain kinase 1 protein heterodimerization activity Molecular function - UBE2D1 7321 ubiquitin-conjugating enzyme E2D 1 protein complex Cellular component 22797923 ZNF519 162655 zinc finger protein 519 DNA binding Molecular function - PIK3C3 5289 phosphatidylinositol 3-kinase, catalytic subunit type 3 insulin receptor signaling pathway Biological process - DHRS9 10170 dehydrogenase/reductase (SDR family) member 9 progesterone metabolic process Biological process 11294878 GRIN2C 2905 glutamate receptor, ionotropic, N-methyl D-aspartate 2C neuromuscular process controlling balance Biological process - CD244 51744 CD244 molecule, natural killer cell receptor 2B4 plasma membrane Cellular component - LMTK2 22853 lemur tyrosine kinase 2 protein serine/threonine kinase activity Molecular function 12393858 HSD17B4 3295 hydroxysteroid (17-beta) dehydrogenase 4 17-beta-hydroxysteroid dehydrogenase (NAD+) activity Molecular function 7487879 PSRC1 84722 proline/serine-rich coiled-coil 1 spindle pole Cellular component 18411309 C14orf1 11161 chromosome 14 open reading frame 1 sterol biosynthetic process Biological process - ACAN 176 aggrecan protein binding Molecular function 17588949 NOP58 51602 NOP58 ribonucleoprotein pre-snoRNP complex Cellular component 17636026 OSR1 130497 odd-skipped related transciption factor 1 ureter urothelium development Biological process - APOBEC4 403314 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative) hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines Molecular function - USP17L11 100287178 ubiquitin specific peptidase 17-like family member 11 proteasome-mediated ubiquitin-dependent protein catabolic process Biological process - MLX 6945 MLX, MAX dimerization protein protein binding Molecular function 16189514 POLA2 23649 polymerase (DNA directed), alpha 2, accessory subunit DNA biosynthetic process Biological process - IQGAP1 8826 IQ motif containing GTPase activating protein 1 small molecule metabolic process Biological process - C12orf10 60314 chromosome 12 open reading frame 10 pigmentation Biological process 16996721 ZFYVE26 23503 zinc finger, FYVE domain containing 26 cytokinesis Biological process 20208530 AAGAB 79719 alpha- and gamma-adaptin binding protein protein transport Biological process - DEFB134 613211 defensin, beta 134 innate immune response Biological process - FRS2 10818 fibroblast growth factor receptor substrate 2 epidermal growth factor receptor signaling pathway Biological process - ACOT4 122970 acyl-CoA thioesterase 4 acyl-CoA hydrolase activity Molecular function 16141203 SUPT5H 6829 suppressor of Ty 5 homolog (S. cerevisiae) gene expression Biological process - MRPL21 219927 mitochondrial ribosomal protein L21 structural constituent of ribosome Molecular function - CCL21 6366 chemokine (C-C motif) ligand 21 cell chemotaxis Biological process 18308860 AGPS 8540 alkylglycerone phosphate synthase FAD binding Molecular function - CYFIP1 23191 cytoplasmic FMR1 interacting protein 1 lamellipodium Cellular component - MDM2 4193 MDM2 proto-oncogene, E3 ubiquitin protein ligase cellular response to UV-C Biological process - C14orf169 79697 chromosome 14 open reading frame 169 protein binding Molecular function 19927124 MX2 4600 MX dynamin-like GTPase 2 cytokine-mediated signaling pathway Biological process - NAB1 4664 NGFI-A binding protein 1 (EGR1 binding protein 1) Schwann cell differentiation Biological process - GNG2 54331 guanine nucleotide binding protein (G protein), gamma 2 energy reserve metabolic process Biological process - ZNF217 7764 zinc finger protein 217 transcription, DNA-templated Biological process - PARD6G 84552 par-6 family cell polarity regulator gamma cell junction assembly Biological process - FNIP1 96459 folliculin interacting protein 1 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process - PTF1A 256297 pancreas specific transcription factor, 1a endocrine pancreas development Biological process - PLD1 5337 phospholipase D1, phosphatidylcholine-specific defense response to Gram-positive bacterium Biological process - HRASLS5 117245 HRAS-like suppressor family, member 5 protein binding Molecular function 25416956 CDH3 1001 cadherin 3, type 1, P-cadherin (placental) negative regulation of catagen Biological process 22696062 ABCC9 10060 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 potassium channel regulator activity Molecular function - MYDGF 56005 myeloid-derived growth factor extracellular space Cellular component 25581518 E2F7 144455 E2F transcription factor 7 positive regulation of transcription from RNA polymerase II promoter Biological process 22903062 ASAP3 55616 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 protein binding Molecular function 25416956 AGPAT5 55326 1-acylglycerol-3-phosphate O-acyltransferase 5 nuclear envelope Cellular component - LIN28B 389421 lin-28 homolog B (C. elegans) mitochondrion Cellular component - CHRM4 1132 cholinergic receptor, muscarinic 4 regulation of locomotion Biological process - RPS6KA5 9252 ribosomal protein S6 kinase, 90kDa, polypeptide 5 positive regulation of CREB transcription factor activity Biological process 18508628 OR5AS1 219447 olfactory receptor, family 5, subfamily AS, member 1 odorant binding Molecular function - MTPAP 55149 mitochondrial poly(A) polymerase identical protein binding Molecular function 21292163 SEC31B 25956 SEC31 homolog B (S. cerevisiae) protein transport Biological process - NDRG4 65009 NDRG family member 4 positive regulation of neuron projection development Biological process - CLCN3 1182 chloride channel, voltage-sensitive 3 protein binding Molecular function 12471024 TLR4 7099 toll-like receptor 4 positive regulation of interleukin-1 production Biological process - NOXO1 124056 NADPH oxidase organizer 1 regulation of respiratory burst Biological process 16636067 EIF2AK1 27102 eukaryotic translation initiation factor 2-alpha kinase 1 negative regulation of hemoglobin biosynthetic process Biological process - OR10G8 219869 olfactory receptor, family 10, subfamily G, member 8 G-protein coupled receptor signaling pathway Biological process - ZSCAN10 84891 zinc finger and SCAN domain containing 10 negative regulation of transcription, DNA-templated Biological process - HCFC1R1 54985 host cell factor C1 regulator 1 (XPO1 dependent) cytoplasm Cellular component - SLC7A1 6541 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 arginine transmembrane transporter activity Molecular function - ADGRL1 22859 adhesion G protein-coupled receptor L1 synapse Cellular component - PLK2 10769 polo-like kinase 2 protein complex binding Molecular function - SLC25A13 10165 solute carrier family 25 (aspartate/glutamate carrier), member 13 glucose metabolic process Biological process - SLC25A47 283600 solute carrier family 25, member 47 mitochondrial inner membrane Cellular component - NKX2-3 159296 NK2 homeobox 3 biological_process Biological process - NUP62 23636 nucleoporin 62kDa transmembrane transport Biological process - A4GALT 53947 alpha 1,4-galactosyltransferase toxic substance binding Molecular function - PSMG1 8624 proteasome (prosome, macropain) assembly chaperone 1 proteasome binding Molecular function - CDC42 998 cell division cycle 42 positive regulation of synapse structural plasticity Biological process - IGFBP6 3489 insulin-like growth factor binding protein 6 extracellular region Cellular component - FOXP2 93986 forkhead box P2 smooth muscle tissue development Biological process - TDRD6 221400 tudor domain containing 6 spermatogenesis Biological process - PTF1A 256297 pancreas specific transcription factor, 1a retinoic acid receptor signaling pathway Biological process - THBS2 7058 thrombospondin 2 platelet alpha granule Cellular component 1737102 NTHL1 4913 nth endonuclease III-like 1 (E. coli) DNA-(apurinic or apyrimidinic site) lyase activity Molecular function 8990169 TRIO 7204 trio Rho guanine nucleotide exchange factor protein serine/threonine kinase activity Molecular function - ALOX5 240 arachidonate 5-lipoxygenase leukotriene biosynthetic process Biological process 21233389 COL14A1 7373 collagen, type XIV, alpha 1 extracellular matrix organization Biological process - RHPN1 114822 rhophilin, Rho GTPase binding protein 1 small GTPase mediated signal transduction Biological process - NFYA 4800 nuclear transcription factor Y, alpha protein binding Molecular function 10571058 GNPTG 84572 N-acetylglucosamine-1-phosphate transferase, gamma subunit UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity Molecular function - YWHAZ 7534 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta postsynaptic density Cellular component - APH1A 51107 APH1A gamma secretase subunit membrane Cellular component 19946888 SLC25A12 8604 solute carrier family 25 (aspartate/glutamate carrier), member 12 L-aspartate transmembrane transport Biological process 11566871 YME1L1 10730 YME1-like 1 ATPase metalloendopeptidase activity Molecular function - EEA1 8411 early endosome antigen 1 vesicle fusion Biological process 9697774 TPGS1 91978 tubulin polyglutamylase complex subunit 1 tubulin-glutamic acid ligase activity Molecular function - SGSH 6448 N-sulfoglucosamine sulfohydrolase glycosaminoglycan catabolic process Biological process - TEK 7010 TEK tyrosine kinase, endothelial positive regulation of phosphatidylinositol 3-kinase signaling Biological process 12816861 GLI2 2736 GLI family zinc finger 2 smoothened signaling pathway involved in ventral spinal cord interneuron specification Biological process - LOR 4014 loricrin structural molecule activity Molecular function 10908733 SULT2B1 6820 sulfotransferase family, cytosolic, 2B, member 1 cytoplasm Cellular component - ENAM 10117 enamelin proteinaceous extracellular matrix Cellular component - ZNF552 79818 zinc finger protein 552 DNA binding Molecular function - DSP 1832 desmoplakin intermediate filament Cellular component 16917092 RPS18 6222 ribosomal protein S18 focal adhesion Cellular component 21423176 AQP1 358 aquaporin 1 (Colton blood group) apical part of cell Cellular component 14675051 QSOX2 169714 quiescin Q6 sulfhydryl oxidase 2 cell redox homeostasis Biological process - VAMP1 6843 vesicle-associated membrane protein 1 (synaptobrevin 1) specific granule membrane Cellular component 11391393 OR5AS1 219447 olfactory receptor, family 5, subfamily AS, member 1 G-protein coupled receptor signaling pathway Biological process - VASH1 22846 vasohibin 1 cell cycle arrest Biological process - UBA52 7311 ubiquitin A-52 residue ribosomal protein fusion product 1 MyD88-dependent toll-like receptor signaling pathway Biological process - RAD9A 5883 RAD9 homolog A (S. pombe) cellular response to ionizing radiation Biological process 21659603 ODF2 4957 outer dense fiber of sperm tails 2 centrosome Cellular component - APOH 350 apolipoprotein H (beta-2-glycoprotein I) triglyceride transport Biological process 7078428 DNAJC10 54431 DnaJ (Hsp40) homolog, subfamily C, member 10 ATPase activator activity Molecular function - VCL 7414 vinculin extracellular vesicle Cellular component 24769233 CRCP 27297 CGRP receptor component innate immune response Biological process - PITX2 5308 paired-like homeodomain 2 positive regulation of myoblast proliferation Biological process - FOXP3 50943 forkhead box P3 histone acetyltransferase binding Molecular function 17360565 FGFR1 2260 fibroblast growth factor receptor 1 positive regulation of MAP kinase activity Biological process 18480409 AGAP6 414189 ArfGAP with GTPase domain, ankyrin repeat and PH domain 6 GTPase activator activity Molecular function - ANO6 196527 anoctamin 6 activation of blood coagulation via clotting cascade Biological process 21107324 GJB2 2706 gap junction protein, beta 2, 26kDa transport Biological process 1324944 TCAP 8557 titin-cap protein binding Molecular function 10984498 LBP 3929 lipopolysaccharide binding protein receptor binding Molecular function 2477488 DAP3 7818 death associated protein 3 mitochondrial ribosome Cellular component - CPT2 1376 carnitine palmitoyltransferase 2 small molecule metabolic process Biological process - ST6GALNAC3 256435 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 glycosphingolipid metabolic process Biological process 17123352 METTL3 56339 methyltransferase like 3 mRNA splicing, via spliceosome Biological process - GCKR 2646 glucokinase (hexokinase 4) regulator nucleoplasm Cellular component - TYRO3 7301 TYRO3 protein tyrosine kinase phosphatidylinositol 3-kinase binding Molecular function 10627473 STUB1 10273 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase endoplasmic reticulum Cellular component 12150907 TRMT2B 79979 tRNA methyltransferase 2 homolog B (S. cerevisiae) tRNA processing Biological process - BMP4 652 bone morphogenetic protein 4 epithelial-mesenchymal cell signaling Biological process - LCK 3932 LCK proto-oncogene, Src family tyrosine kinase hemopoiesis Biological process 12884910 GBA 2629 glucosidase, beta, acid skin morphogenesis Biological process - CAB39L 81617 calcium binding protein 39-like extracellular exosome Cellular component 23376485 NUGGC 389643 nuclear GTPase, germinal center associated nucleus Cellular component - CDT1 81620 chromatin licensing and DNA replication factor 1 protein binding Molecular function 11125146 SLC6A4 6532 solute carrier family 6 (neurotransmitter transporter), member 4 cytosol Cellular component 19270731 DOCK2 1794 dedicator of cytokinesis 2 membrane Cellular component 19946888 ITGA6 3655 integrin, alpha 6 external side of plasma membrane Cellular component - FSCN2 25794 fascin actin-bundling protein 2, retinal actin binding Molecular function - FERMT2 10979 fermitin family member 2 cytoplasm Cellular component 22699938 FSCN1 6624 fascin actin-bundling protein 1 cell migration Biological process 20393565 OR6C74 254783 olfactory receptor, family 6, subfamily C, member 74 detection of chemical stimulus involved in sensory perception of smell Biological process - PSMA4 5685 proteasome (prosome, macropain) subunit, alpha type, 4 G1/S transition of mitotic cell cycle Biological process - CCP110 9738 centriolar coiled coil protein 110kDa mitotic cell cycle Biological process - BRSK1 84446 BR serine/threonine kinase 1 nucleus Cellular component 15150265 SHROOM2 357 shroom family member 2 filamentous actin Cellular component - OR6N2 81442 olfactory receptor, family 6, subfamily N, member 2 detection of chemical stimulus involved in sensory perception Biological process - KCNN4 3783 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 Intermediate conductance calcium-activated potassium channel activity Molecular function - RPS6KB1 6198 ribosomal protein S6 kinase, 70kDa, polypeptide 1 germ cell development Biological process - PRKCH 5583 protein kinase C, eta platelet activation Biological process - RNH1 6050 ribonuclease/angiogenin inhibitor 1 angiogenin-PRI complex Cellular component 3470787 NTRK2 4915 neurotrophic tyrosine kinase, receptor, type 2 negative regulation of anoikis Biological process - SATB1 6304 SATB homeobox 1 chromatin binding Molecular function - CMPK2 129607 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial dTTP biosynthetic process Biological process - MMP19 4327 matrix metallopeptidase 19 response to hormone Biological process - MEST 4232 mesoderm specific transcript regulation of lipid storage Biological process - SLC29A1 2030 solute carrier family 29 (equilibrative nucleoside transporter), member 1 sleep Biological process - FNBP1 23048 formin binding protein 1 protein binding Molecular function 11438682 GALR1 2587 galanin receptor 1 positive regulation of cortisol secretion Biological process 17982695 DSCC1 79075 DNA replication and sister chromatid cohesion 1 nucleoplasm Cellular component 16682347 NONO 4841 non-POU domain containing, octamer-binding RNA splicing Biological process - NIPBL 25836 Nipped-B homolog (Drosophila) negative regulation of transcription from RNA polymerase II promoter Biological process 18854353 COL1A2 1278 collagen, type I, alpha 2 cellular response to amino acid stimulus Biological process - NLRP5 126206 NLR family, pyrin domain containing 5 cellular protein complex assembly Biological process - CTDSP1 58190 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 regulation of transcription from RNA polymerase II promoter Biological process 12721286 HLA-F 3134 major histocompatibility complex, class I, F receptor binding Molecular function - CETP 1071 cholesteryl ester transfer protein, plasma high-density lipoprotein particle remodeling Biological process 2586614 LANCL1 10314 LanC lantibiotic synthetase component C-like 1 (bacterial) extracellular exosome Cellular component 23376485 GTF2H2 2966 general transcription factor IIH, polypeptide 2, 44kDa negative regulation of gene expression, epigenetic Biological process - PIK3R6 146850 phosphoinositide-3-kinase, regulatory subunit 6 1-phosphatidylinositol-3-kinase regulator activity Molecular function - SMO 6608 smoothened, frizzled class receptor G-protein coupled receptor activity Molecular function - ARRB1 408 arrestin, beta 1 positive regulation of GTPase activity Biological process 15611106 PRDM6 93166 PR domain containing 6 neurogenesis Biological process - WFDC2 10406 WAP four-disulfide core domain 2 spermatogenesis Biological process 1686187 TH 7054 tyrosine hydroxylase response to corticosterone Biological process - HES1 3280 hes family bHLH transcription factor 1 labyrinthine layer blood vessel development Biological process - SPAG9 9043 sperm associated antigen 9 acrosomal vesicle Cellular component - MYO10 4651 myosin X ruffle Cellular component - FSHR 2492 follicle stimulating hormone receptor plasma membrane Cellular component - TFF2 7032 trefoil factor 2 positive regulation of cell proliferation Biological process - PLAUR 5329 plasminogen activator, urokinase receptor blood coagulation Biological process - MCIDAS 345643 multiciliate differentiation and DNA synthesis associated cell cycle protein transcription, DNA-templated Biological process - VWCE 220001 von Willebrand factor C and EGF domains positive regulation of cell proliferation Biological process - CYP7A1 1581 cytochrome P450, family 7, subfamily A, polypeptide 1 iron ion binding Molecular function - PTGES3 10728 prostaglandin E synthase 3 (cytosolic) chaperone cofactor-dependent protein refolding Biological process 12853476 SCN3B 55800 sodium channel, voltage gated, type III beta subunit cardiac muscle cell action potential involved in contraction Biological process 21051419 YY1 7528 YY1 transcription factor transcription coactivator activity Molecular function 1946405 ZNF878 729747 zinc finger protein 878 nucleic acid binding Molecular function - EVC 2121 Ellis van Creveld protein ciliary membrane Cellular component - MGST1 4257 microsomal glutathione S-transferase 1 response to lipopolysaccharide Biological process - CLIC2 1193 chloride intracellular channel 2 glutathione peroxidase activity Molecular function 15147738 COG4 25839 component of oligomeric golgi complex 4 Golgi membrane Cellular component - ARPC3 10094 actin related protein 2/3 complex, subunit 3, 21kDa structural constituent of cytoskeleton Molecular function 11741539 NCKAP1 10787 NCK-associated protein 1 Rac GTPase binding Molecular function 21107423 C17orf49 124944 chromosome 17 open reading frame 49 MLL1 complex Cellular component 15960975 EPHX1 2052 epoxide hydrolase 1, microsomal (xenobiotic) response to toxic substance Biological process - KDM5A 5927 lysine (K)-specific demethylase 5A oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Molecular function - CAMK2D 817 calcium/calmodulin-dependent protein kinase II delta peptidyl-threonine phosphorylation Biological process 22514276 TNF 7124 tumor necrosis factor extracellular matrix organization Biological process - MLLT3 4300 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 segment specification Biological process - CDO1 1036 cysteine dioxygenase type 1 lactation Biological process - SNIP1 79753 Smad nuclear interacting protein 1 regulation of transcription, DNA-templated Biological process - HIST1H4A 8359 histone cluster 1, H4a regulation of gene expression, epigenetic Biological process - CLCN6 1185 chloride channel, voltage-sensitive 6 regulation of anion transmembrane transport Biological process 8543009 AVEN 57099 apoptosis, caspase activation inhibitor intracellular Cellular component 10949025 CCNI 10983 cyclin I spermatogenesis Biological process 9705831 NR2C2 7182 nuclear receptor subfamily 2, group C, member 2 steroid hormone receptor activity Molecular function - F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 positive regulation of actin filament depolymerization Biological process 17500066 GNG2 54331 guanine nucleotide binding protein (G protein), gamma 2 blood coagulation Biological process - AQP1 358 aquaporin 1 (Colton blood group) small molecule metabolic process Biological process - MSH2 4436 mutS homolog 2 maintenance of DNA repeat elements Biological process 16388310 FGFRL1 53834 fibroblast growth factor receptor-like 1 cell-cell adhesion via plasma-membrane adhesion molecules Biological process 18061161 MAPK7 5598 mitogen-activated protein kinase 7 mitogen-activated protein kinase binding Molecular function 23043106 NGF 4803 nerve growth factor (beta polypeptide) positive regulation of neurotrophin TRK receptor signaling pathway Biological process - XPNPEP3 63929 X-prolyl aminopeptidase 3, mitochondrial metallopeptidase activity Molecular function - MSRA 4482 methionine sulfoxide reductase A mitochondrion Cellular component - STMN1 3925 stathmin 1 negative regulation of microtubule polymerization Biological process - CCDC9 26093 coiled-coil domain containing 9 poly(A) RNA binding Molecular function 22658674 SOX9 6662 SRY (sex determining region Y)-box 9 cartilage condensation Biological process - INTS9 55756 integrator complex subunit 9 snRNA processing Biological process 16239144 EDN1 1906 endothelin 1 protein kinase C deactivation Biological process 16820593 ZNF100 163227 zinc finger protein 100 regulation of transcription, DNA-templated Biological process - SLC1A6 6511 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 integral component of plasma membrane Cellular component 7791878 PTGR1 22949 prostaglandin reductase 1 zinc ion binding Molecular function - SLA2 84174 Src-like-adaptor 2 regulation of immune response Biological process 11696592 CHD1L 9557 chromodomain helicase DNA binding protein 1-like DNA duplex unwinding Biological process 19661379 HMGB3 3149 high mobility group box 3 DNA binding, bending Molecular function - CYGB 114757 cytoglobin protein binding Molecular function 25416956 TAF1 6872 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa peptidyl-serine phosphorylation Biological process 8625415 BAD 572 BCL2-associated agonist of cell death extrinsic apoptotic signaling pathway via death domain receptors Biological process - LIF 3976 leukemia inhibitory factor positive regulation of astrocyte differentiation Biological process - MPHOSPH8 54737 M-phase phosphoprotein 8 nucleolus Cellular component - PSEN2 5664 presenilin 2 cell cortex Cellular component - MYB 4602 v-myb avian myeloblastosis viral oncogene homolog chromatin binding Molecular function - CARD9 64170 caspase recruitment domain family, member 9 response to exogenous dsRNA Biological process - TAGAP 117289 T-cell activation RhoGTPase activating protein guanyl-nucleotide exchange factor activity Molecular function - RAF1 5894 Raf-1 proto-oncogene, serine/threonine kinase small GTPase binding Molecular function 12194967 SLC39A6 25800 solute carrier family 39 (zinc transporter), member 6 transmembrane transport Biological process - TMEM109 79073 transmembrane protein 109 extracellular exosome Cellular component 19199708 PPP2CB 5516 protein phosphatase 2, catalytic subunit, beta isozyme protein phosphatase type 2A complex Cellular component 8206937 HS3ST2 9956 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 integral component of membrane Cellular component - DMP1 1758 dentin matrix acidic phosphoprotein 1 nucleolus Cellular component - ATG7 10533 autophagy related 7 macroautophagy Biological process - PITPNB 23760 phosphatidylinositol transfer protein, beta lipid metabolic process Biological process 8541325 LMO4 8543 LIM domain only 4 neural tube closure Biological process - PEX11B 8799 peroxisomal biogenesis factor 11 beta extracellular exosome Cellular component 23376485 BLOC1S6 26258 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin extrinsic component of membrane Cellular component 12019270 RPTOR 57521 regulatory associated protein of MTOR, complex 1 positive regulation of transcription from RNA polymerase III promoter Biological process 20233713 NR2F2 7026 nuclear receptor subfamily 2, group F, member 2 blood vessel morphogenesis Biological process - VAMP2 6844 vesicle-associated membrane protein 2 (synaptobrevin 2) SNAP receptor activity Molecular function - FUT7 2529 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) fucosylation Biological process 11698403 DNM1L 10059 dynamin 1-like positive regulation of apoptotic process Biological process 20850011 MAP1LC3A 84557 microtubule-associated protein 1 light chain 3 alpha protein binding Molecular function 11096062 NPHS1 4868 nephrosis 1, congenital, Finnish type (nephrin) myosin binding Molecular function 21402783 IMP3 55272 IMP3, U3 small nucleolar ribonucleoprotein nucleus Cellular component - EVI5 7813 ecotropic viral integration site 5 spindle Cellular component - CASP1 834 caspase 1, apoptosis-related cysteine peptidase programmed necrotic cell death Biological process - KCNG4 93107 potassium channel, voltage gated modifier subfamily G, member 4 plasma membrane Cellular component - HSH2D 84941 hematopoietic SH2 domain containing negative regulation of mitochondrial depolarization Biological process - RPL19 6143 ribosomal protein L19 gene expression Biological process - ZCCHC6 79670 zinc finger, CCHC domain containing 6 RNA uridylyltransferase activity Molecular function 17353264 SLC5A1 6523 solute carrier family 5 (sodium/glucose cotransporter), member 1 integral component of plasma membrane Cellular component 8563765 MTM1 4534 myotubularin 1 cytosol Cellular component - MRPS24 64951 mitochondrial ribosomal protein S24 mitochondrial translational initiation Biological process - NFKB2 4791 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) sequence-specific DNA binding transcription factor activity Molecular function 1760839 GFPT1 2673 glutamine--fructose-6-phosphate transaminase 1 dolichol-linked oligosaccharide biosynthetic process Biological process - EHD4 30844 EH-domain containing 4 positive regulation of peptidyl-tyrosine phosphorylation Biological process - FZR1 51343 fizzy/cell division cycle 20 related 1 (Drosophila) mitotic nuclear division Biological process - PROX1 5629 prospero homeobox 1 venous blood vessel morphogenesis Biological process - RAB8B 51762 RAB8B, member RAS oncogene family plasma membrane Cellular component - HLX 3142 H2.0-like homeobox regulation of transcription, DNA-templated Biological process - MAPK8 5599 mitogen-activated protein kinase 8 MyD88-independent toll-like receptor signaling pathway Biological process - RAB7A 7879 RAB7A, member RAS oncogene family phagosome acidification Biological process 21255211 B3GALNT2 148789 beta-1,3-N-acetylgalactosaminyltransferase 2 endoplasmic reticulum Cellular component 23453667 WNK2 65268 WNK lysine deficient protein kinase 2 intracellular signal transduction Biological process - GSTM2 2946 glutathione S-transferase mu 2 (muscle) glutathione transferase activity Molecular function 16549767 GCK 2645 glucokinase (hexokinase 4) glycolytic process Biological process - NLGN1 22871 neuroligin 1 synapse assembly Biological process - DPM2 8818 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit enzyme regulator activity Molecular function - SH3D19 152503 SH3 domain containing 19 nucleoplasm Cellular component - IRF1 3659 interferon regulatory factor 1 regulation of cell cycle Biological process 11846974 IFT57 55081 intraflagellar transport 57 organelle organization Biological process - BCL2L11 10018 BCL2-like 11 (apoptosis facilitator) positive regulation of apoptotic process Biological process - SIRT3 23410 sirtuin 3 peptidyl-lysine deacetylation Biological process 22309213 RPL32 6161 ribosomal protein L32 centrosome Cellular component - VIPR2 7434 vasoactive intestinal peptide receptor 2 plasma membrane Cellular component - PRKAR2B 5577 protein kinase, cAMP-dependent, regulatory, type II, beta epidermal growth factor receptor signaling pathway Biological process - CEACAM5 1048 carcinoembryonic antigen-related cell adhesion molecule 5 anchored component of membrane Cellular component - GATA5 140628 GATA binding protein 5 transcription from RNA polymerase II promoter Biological process - THEMIS2 9473 thymocyte selection associated family member 2 protein binding Molecular function 25416956 AKAP8L 26993 A kinase (PRKA) anchor protein 8-like cytoplasm Cellular component - CASP6 839 caspase 6, apoptosis-related cysteine peptidase epithelial cell differentiation Biological process 21492153 FBXL15 79176 F-box and leucine-rich repeat protein 15 bone mineralization Biological process - ST13 6767 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) extracellular exosome Cellular component 19056867 ANXA9 8416 annexin A9 protein homodimerization activity Molecular function 10899159 UGT1A3 54659 UDP glucuronosyltransferase 1 family, polypeptide A3 negative regulation of cellular glucuronidation Biological process 20610558 LMX1A 4009 LIM homeobox transcription factor 1, alpha negative regulation of neuron differentiation Biological process - RARA 5914 retinoic acid receptor, alpha positive regulation of binding Biological process 20080953 NUCB2 4925 nucleobindin 2 Golgi apparatus Cellular component - SPARC 6678 secreted protein, acidic, cysteine-rich (osteonectin) extracellular matrix binding Molecular function - RAC2 5880 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) G-protein coupled receptor signaling pathway Biological process - COL4A3 1285 collagen, type IV, alpha 3 (Goodpasture antigen) extracellular matrix disassembly Biological process - ZNF75A 7627 zinc finger protein 75a DNA binding Molecular function - HADH 3033 hydroxyacyl-CoA dehydrogenase mitochondrial matrix Cellular component - REN 5972 renin proteolysis Biological process 12045255 SLC8A1 6546 solute carrier family 8 (sodium/calcium exchanger), member 1 heart morphogenesis Biological process - RSL1D1 26156 ribosomal L1 domain containing 1 regulation of cellular senescence Biological process 18678645 NSUN7 79730 NOP2/Sun domain family, member 7 methyltransferase activity Molecular function - LYG2 254773 lysozyme G-like 2 lysozyme activity Molecular function - DLG4 1742 discs, large homolog 4 (Drosophila) juxtaparanode region of axon Cellular component - SHPRH 257218 SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase helicase activity Molecular function - VTA1 51534 vesicle (multivesicular body) trafficking 1 multivesicular body sorting pathway Biological process 15644320 SOX9 6662 SRY (sex determining region Y)-box 9 cAMP-mediated signaling Biological process 10805756 HTR5A 3361 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled integral component of plasma membrane Cellular component - EIF2AK3 9451 eukaryotic translation initiation factor 2-alpha kinase 3 negative regulation of myelination Biological process - RNF34 80196 ring finger protein 34, E3 ubiquitin protein ligase cellular response to cold Biological process - SGK3 23678 serum/glucocorticoid regulated kinase family, member 3 potassium channel regulator activity Molecular function 16460280 MVD 4597 mevalonate (diphospho) decarboxylase dolichyl diphosphate biosynthetic process Biological process - SLC39A13 91252 solute carrier family 39 (zinc transporter), member 13 Golgi apparatus Cellular component 18985159 CBX5 23468 chromobox homolog 5 nucleolus Cellular component 9636146 OR4C16 219428 olfactory receptor, family 4, subfamily C, member 16 (gene/pseudogene) G-protein coupled receptor activity Molecular function - ACOX3 8310 acyl-CoA oxidase 3, pristanoyl membrane Cellular component 19946888 ZNF622 90441 zinc finger protein 622 positive regulation of kinase activity Biological process 21771788 ILF3 3609 interleukin enhancer binding factor 3, 90kDa protein binding Molecular function 10574923 CHD7 55636 chromodomain helicase DNA binding protein 7 T cell differentiation Biological process 17684005 OPRK1 4986 opioid receptor, kappa 1 defense response to virus Biological process 8755601 EGLN3 112399 egl-9 family hypoxia-inducible factor 3 protein hydroxylation Biological process 19584355 MYO1F 4542 myosin IF filamentous actin Cellular component - CCNY 219771 cyclin Y extracellular exosome Cellular component 23376485 SGPP2 130367 sphingosine-1-phosphate phosphatase 2 sphingolipid metabolic process Biological process - CALR 811 calreticulin antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent Biological process - SLC26A2 1836 solute carrier family 26 (anion exchanger), member 2 secondary active sulfate transmembrane transporter activity Molecular function - SFT2D2 375035 SFT2 domain containing 2 integral component of membrane Cellular component - APOA1 335 apolipoprotein A-I organ regeneration Biological process - USP40 55230 ubiquitin specific peptidase 40 cytoplasm Cellular component - PRDM8 56978 PR domain containing 8 histone methyltransferase activity (H3-K9 specific) Molecular function - PARVA 55742 parvin, alpha actin cytoskeleton Cellular component - UNC13D 201294 unc-13 homolog D (C. elegans) Rab GTPase binding Molecular function 22899725 HDAC6 10013 histone deacetylase 6 caveola Cellular component 18356165 RANBP2 5903 RAN binding protein 2 gene expression Biological process - SETD7 80854 SET domain containing (lysine methyltransferase) 7 peptidyl-lysine monomethylation Biological process 17108971 SIGIRR 59307 single immunoglobulin and toll-interleukin 1 receptor (TIR) domain protein binding Molecular function 12925853 YWHAE 7531 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon viral process Biological process - FHL2 2274 four and a half LIM domains 2 small molecule metabolic process Biological process - IL15RA 3601 interleukin 15 receptor, alpha integral component of membrane Cellular component - IRX3 79191 iroquois homeobox 3 negative regulation of neuron differentiation Biological process - SIRPA 140885 signal-regulatory protein alpha membrane Cellular component 9062191 IGHA1 3493 immunoglobulin heavy constant alpha 1 antibacterial humoral response Biological process 23250751 TGFBR2 7048 transforming growth factor, beta receptor II (70/80kDa) transforming growth factor beta receptor activity, type II Molecular function - CIB1 10519 calcium and integrin binding 1 (calmyrin) growth cone Cellular component 21215777 ST14 6768 suppression of tumorigenicity 14 (colon carcinoma) plasma membrane Cellular component 10373424 PAPPA2 60676 pappalysin 2 bone morphogenesis Biological process - MKNK1 8569 MAP kinase interacting serine/threonine kinase 1 nucleus Cellular component - PDCD2 5134 programmed cell death 2 protein binding Molecular function 19146857 CCKBR 887 cholecystokinin B receptor positive regulation of cell proliferation Biological process 10913157 RHBG 57127 Rh family, B glycoprotein (gene/pseudogene) ammonium transmembrane transport Biological process - CDKN2A 1029 cyclin-dependent kinase inhibitor 2A mitotic cell cycle Biological process - FRS2 10818 fibroblast growth factor receptor substrate 2 optic placode formation involved in camera-type eye formation Biological process - TMCO6 55374 transmembrane and coiled-coil domains 6 integral component of membrane Cellular component - TAF1L 138474 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like transcription initiation from RNA polymerase II promoter Biological process - EIF2A 83939 eukaryotic translation initiation factor 2A, 65kDa extracellular space Cellular component 22664934 CXCL10 3627 chemokine (C-X-C motif) ligand 10 cellular response to lipopolysaccharide Biological process 23776175 CBX3 11335 chromobox homolog 3 chromosome, centromeric region Cellular component 10504293 TROVE2 6738 TROVE domain family, member 2 RNA binding Molecular function 3200833 AMBP 259 alpha-1-microglobulin/bikunin precursor receptor-mediated endocytosis Biological process - HACD4 401494 3-hydroxyacyl-CoA dehydratase 4 endoplasmic reticulum membrane Cellular component - DDOST 1650 dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) protein N-linked glycosylation Biological process 9642163 SLC5A10 125206 solute carrier family 5 (sodium/sugar cotransporter), member 10 sodium ion transport Biological process - NCOR1 9611 nuclear receptor corepressor 1 transcription, DNA-templated Biological process - CREBRF 153222 CREB3 regulatory factor transport Biological process - LYN 4067 LYN proto-oncogene, Src family tyrosine kinase ion channel binding Molecular function 12538589 CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa negative regulation of mitotic cell cycle, embryonic Biological process - NCK2 8440 NCK adaptor protein 2 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation Biological process 16835242 MLLT3 4300 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 regulation of transcription, DNA-templated Biological process - ZNF181 339318 zinc finger protein 181 metal ion binding Molecular function - ADM 133 adrenomedullin positive regulation of vasculogenesis Biological process - PKD2 5311 polycystic kidney disease 2 (autosomal dominant) metanephric distal tubule development Biological process 11891195 C4B 721 complement component 4B (Chido blood group) extracellular region Cellular component - POU3F3 5455 POU class 3 homeobox 3 transcription, DNA-templated Biological process - EMD 2010 emerin endoplasmic reticulum Cellular component - LIN7A 8825 lin-7 homolog A (C. elegans) asymmetric protein localization Biological process - MMP14 4323 matrix metallopeptidase 14 (membrane-inserted) negative regulation of focal adhesion assembly Biological process - TGFBR1 7046 transforming growth factor, beta receptor 1 receptor signaling protein activity Molecular function - AURKB 9212 aurora kinase B positive regulation of cytokinesis Biological process 19774610 GGH 8836 gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) response to ethanol Biological process - ZNF598 90850 zinc finger protein 598 poly(A) RNA binding Molecular function 22658674 GTF2E1 2960 general transcription factor IIE, polypeptide 1, alpha 56kDa transcription elongation from RNA polymerase II promoter Biological process - GALK1 2584 galactokinase 1 carbohydrate metabolic process Biological process - NLGN4Y 22829 neuroligin 4, Y-linked integral component of plasma membrane Cellular component - AKR1C3 8644 aldo-keto reductase family 1, member C3 retinal dehydrogenase activity Molecular function 21851338 KIT 3815 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog embryonic hemopoiesis Biological process - WDR45 11152 WD repeat domain 45 protein localization to pre-autophagosomal structure Biological process - LRRK2 120892 leucine-rich repeat kinase 2 activation of MAPKK activity Biological process 19302196 ELAVL1 1994 ELAV like RNA binding protein 1 nucleotide binding Molecular function - SFRP4 6424 secreted frizzled-related protein 4 negative regulation of cell proliferation Biological process 14760084 TLR8 51311 toll-like receptor 8 microglial cell activation Biological process - NR3C2 4306 nuclear receptor subfamily 3, group C, member 2 endoplasmic reticulum membrane Cellular component - HTR4 3360 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled regulation of appetite Biological process - NCOR1 9611 nuclear receptor corepressor 1 histone deacetylase complex Cellular component 18326024 NOS1AP 9722 nitric oxide synthase 1 (neuronal) adaptor protein regulation of apoptotic process Biological process 20431962 SMN2 6607 survival of motor neuron 2, centromeric nervous system development Biological process - CARF 79800 calcium responsive transcription factor DNA binding Molecular function 11832226 CORO1A 11151 coronin, actin binding protein, 1A extracellular exosome Cellular component 20458337 MUC12 10071 mucin 12, cell surface associated post-translational protein modification Biological process - MSTN 2660 myostatin extracellular space Cellular component - FAM107B 83641 family with sequence similarity 107, member B sensory perception of sound Biological process - IER3 8870 immediate early response 3 negative regulation of apoptotic process Biological process 9703517 UEVLD 55293 UEV and lactate/malate dehyrogenase domains protein transport Biological process - PMF1 11243 polyamine-modulated factor 1 transcription from RNA polymerase II promoter Biological process 10419538 UPF3B 65109 UPF3 regulator of nonsense transcripts homolog B (yeast) mRNA 3'-end processing Biological process - TCF20 6942 transcription factor 20 (AR1) zinc ion binding Molecular function - MYO1E 4643 myosin IE protein binding Molecular function 17257598 WNT5A 7474 wingless-type MMTV integration site family, member 5A cell surface Cellular component - ST13 6767 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) protein binding Molecular function 21163940 HDGFRP3 50810 hepatoma-derived growth factor, related protein 3 nucleoplasm Cellular component - SCYL3 57147 SCY1-like 3 (S. cerevisiae) ATP binding Molecular function - GPR61 83873 G protein-coupled receptor 61 biological_process Biological process - PDE3A 5139 phosphodiesterase 3A, cGMP-inhibited integral component of membrane Cellular component - PTEN 5728 phosphatase and tensin homolog response to estradiol Biological process - AHI1 54806 Abelson helper integration site 1 positive regulation of polarized epithelial cell differentiation Biological process - ISOC2 79763 isochorismatase domain containing 2 nucleus Cellular component 17658461 HLA-DRB3 3125 major histocompatibility complex, class II, DR beta 3 inflammatory response to antigenic stimulus Biological process 15795121 MKS1 54903 Meckel syndrome, type 1 ciliary basal body Cellular component 19208769 GATA3 2625 GATA binding protein 3 T-helper 2 cell differentiation Biological process - RPL35A 6165 ribosomal protein L35a translational termination Biological process - GOLGB1 2804 golgin B1 protein binding Molecular function 14980500 S1PR4 8698 sphingosine-1-phosphate receptor 4 positive regulation of cytosolic calcium ion concentration Biological process 10679247 DTX1 1840 deltex 1, E3 ubiquitin ligase cytoplasm Cellular component 9590294 MGAT2 4247 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase Golgi apparatus Cellular component - TOE1 114034 target of EGR1, member 1 (nuclear) protein binding Molecular function 19508870 SEC11C 90701 SEC11 homolog C (S. cerevisiae) gene expression Biological process - PCNA 5111 proliferating cell nuclear antigen cell proliferation Biological process 2565339 NRXN1 9378 neurexin 1 positive regulation of establishment of protein localization to plasma membrane Biological process - NPVF 64111 neuropeptide VF precursor neuropeptide signaling pathway Biological process 11025660 FBXO45 200933 F-box protein 45 neuron migration Biological process - CBS 875 cystathionine-beta-synthase cystathionine beta-synthase activity Molecular function - CDK6 1021 cyclin-dependent kinase 6 ATP binding Molecular function 9751050 TRIM36 55521 tripartite motif containing 36 protein ubiquitination Biological process - AMPD3 272 adenosine monophosphate deaminase 3 cytosol Cellular component - NKX2-1 7080 NK2 homeobox 1 intronic transcription regulatory region sequence-specific DNA binding Molecular function - GTF3C5 9328 general transcription factor IIIC, polypeptide 5, 63kDa DNA binding Molecular function 17409385 PRMT7 54496 protein arginine methyltransferase 7 protein-arginine omega-N monomethyltransferase activity Molecular function 15044439 FN1 2335 fibronectin 1 extracellular matrix disassembly Biological process - KIF20B 9585 kinesin family member 20B ATP binding Molecular function - BECN1 8678 beclin 1, autophagy related cellular response to glucose starvation Biological process - ZBTB49 166793 zinc finger and BTB domain containing 49 cell cycle arrest Biological process 25245946 PPP2R5B 5526 protein phosphatase 2, regulatory subunit B', beta cytoplasm Cellular component 8703017 TMEM30A 55754 transmembrane protein 30A transport vesicle membrane Cellular component - KHK 3795 ketohexokinase (fructokinase) cytoplasm Cellular component - SLC25A15 10166 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 mitochondrial ornithine transport Biological process 10369256 SCAMP4 113178 secretory carrier membrane protein 4 integral component of membrane Cellular component - DNPEP 23549 aspartyl aminopeptidase peptide metabolic process Biological process 9632644 PIK3C2A 5286 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha phosphatidylinositol binding Molecular function - TMEM161A 54929 transmembrane protein 161A integral component of membrane Cellular component - EPHA1 2041 EPH receptor A1 positive regulation of cell proliferation Biological process 20043122 CASP9 842 caspase 9, apoptosis-related cysteine peptidase intrinsic apoptotic signaling pathway Biological process - PDGFRA 5156 platelet-derived growth factor receptor, alpha polypeptide fibroblast growth factor receptor signaling pathway Biological process - DHFR 1719 dihydrofolate reductase nucleotide biosynthetic process Biological process - COMMD9 29099 COMM domain containing 9 protein binding Molecular function 21778237 FCER1G 2207 Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide innate immune response Biological process - NUP155 9631 nucleoporin 155kDa regulation of glucose transport Biological process - ATP13A1 57130 ATPase type 13A1 molecular_function Molecular function - KBTBD7 84078 kelch repeat and BTB (POZ) domain containing 7 protein binding Molecular function 16169070 DHX32 55760 DEAH (Asp-Glu-Ala-His) box polypeptide 32 protein binding Molecular function 25416956 NCOA6 23054 nuclear receptor coactivator 6 chromatin binding Molecular function - INPP5J 27124 inositol polyphosphate-5-phosphatase J cytosol Cellular component - REV3L 5980 REV3-like, polymerase (DNA directed), zeta, catalytic subunit zeta DNA polymerase complex Cellular component 20164194 PTGES3 10728 prostaglandin E synthase 3 (cytosolic) telomere maintenance Biological process 12135483 TNNI2 7136 troponin I type 2 (skeletal, fast) nucleus Cellular component 18331830 SUMO1 7341 small ubiquitin-like modifier 1 nucleoplasm Cellular component - RHBDD1 84236 rhomboid domain containing 1 endoplasmic reticulum quality control compartment Cellular component - TSSK3 81629 testis-specific serine kinase 3 protein phosphorylation Biological process - PAPOLB 56903 poly(A) polymerase beta (testis specific) mRNA polyadenylation Biological process - CHRNA10 57053 cholinergic receptor, nicotinic, alpha 10 (neuronal) acetylcholine-gated channel complex Cellular component - HOXC9 3225 homeobox C9 sequence-specific DNA binding Molecular function - CYP4F11 57834 cytochrome P450, family 4, subfamily F, polypeptide 11 inflammatory response Biological process 10964514 BCL2L2 599 BCL2-like 2 negative regulation of apoptotic process Biological process 17289999 ZNF483 158399 zinc finger protein 483 DNA binding Molecular function - KIF3B 9371 kinesin family member 3B intraciliary transport particle Cellular component - APOB 338 apolipoprotein B triglyceride catabolic process Biological process - RFX2 5990 regulatory factor X, 2 (influences HLA class II expression) sequence-specific DNA binding transcription factor activity Molecular function - C6orf106 64771 chromosome 6 open reading frame 106 biological_process Biological process - ZIC3 7547 Zic family member 3 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 17764085 PLA2G2A 5320 phospholipase A2, group IIA (platelets, synovial fluid) extracellular space Cellular component 17069818 IRAK1 3654 interleukin-1 receptor-associated kinase 1 response to interleukin-1 Biological process 10383454 PSMC5 5705 proteasome (prosome, macropain) 26S subunit, ATPase, 5 proteasome accessory complex Cellular component - CCDC93 54520 coiled-coil domain containing 93 protein binding Molecular function 25355947 IFIH1 64135 interferon induced with helicase C domain 1 zinc ion binding Molecular function 19380577 CTHRC1 115908 collagen triple helix repeat containing 1 positive regulation of osteoblast differentiation Biological process - LSG1 55341 large 60S subunit nuclear export GTPase 1 cytoplasm Cellular component - MERTK 10461 MER proto-oncogene, tyrosine kinase cell-cell signaling Biological process 8086340 TLR3 7098 toll-like receptor 3 identical protein binding Molecular function 25217833 PSPH 5723 phosphoserine phosphatase L-serine biosynthetic process Biological process - WNT8A 7478 wingless-type MMTV integration site family, member 8A canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment Biological process 20559569 INTS5 80789 integrator complex subunit 5 integrator complex Cellular component 16239144 DNAJC5 80331 DnaJ (Hsp40) homolog, subfamily C, member 5 synaptic vesicle Cellular component - HLA-DMB 3109 major histocompatibility complex, class II, DM beta MHC class II protein complex Cellular component 22247549 COPB1 1315 coatomer protein complex, subunit beta 1 cytosol Cellular component - NLGN2 57555 neuroligin 2 regulation of synaptic transmission Biological process - GJA9 81025 gap junction protein, alpha 9, 59kDa connexon complex Cellular component - CLPSL2 389383 colipase-like 2 extracellular region Cellular component - MECOM 2122 MDS1 and EVI1 complex locus aggresome Cellular component - KCNMB1 3779 potassium channel subfamily M regulatory beta subunit 1 calcium-activated potassium channel activity Molecular function - KCND1 3750 potassium channel, voltage gated Shal related subfamily D, member 1 cellular_component Cellular component - RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region negative regulation of ossification Biological process - KIF17 57576 kinesin family member 17 protein transport Biological process - GPIHBP1 338328 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 apical plasma membrane Cellular component 20620994 BDNF 627 brain-derived neurotrophic factor cellular response to tumor necrosis factor Biological process - OR6C3 254786 olfactory receptor, family 6, subfamily C, member 3 integral component of membrane Cellular component 10706615 TRIB1 10221 tribbles pseudokinase 1 regulation of MAP kinase activity Biological process 15299019 ZNF560 147741 zinc finger protein 560 transcription, DNA-templated Biological process - ADAMTS9 56999 ADAM metallopeptidase with thrombospondin type 1 motif, 9 extracellular matrix Cellular component 22261194 MAP3K15 389840 mitogen-activated protein kinase kinase kinase 15 activation of MAPKK activity Biological process - PKDCC 91461 protein kinase domain containing, cytoplasmic plasmodesma Cellular component - ATP7B 540 ATPase, Cu++ transporting, beta polypeptide perinuclear region of cytoplasm Cellular component 16939419 SRRT 51593 serrate, RNA effector molecule cell proliferation Biological process - BAK1 578 BCL2-antagonist/killer 1 myeloid cell homeostasis Biological process - HNF4G 3174 hepatocyte nuclear factor 4, gamma positive regulation of transcription, DNA-templated Biological process - METTL21C 196541 methyltransferase like 21C nucleus Cellular component - TPRN 286262 taperin molecular_function Molecular function - ARID4B 51742 AT rich interactive domain 4B (RBP1-like) histone H4-K20 trimethylation Biological process - NRBP1 29959 nuclear receptor binding protein 1 lamellipodium Cellular component - SCN10A 6336 sodium channel, voltage gated, type X alpha subunit sensory perception Biological process 9839820 ALDH1L2 160428 aldehyde dehydrogenase 1 family, member L2 biosynthetic process Biological process - ZNF649 65251 zinc finger protein 649 nucleus Cellular component - KIF1C 10749 kinesin family member 1C kinesin complex Cellular component - S100A12 6283 S100 calcium binding protein A12 nucleus Cellular component 15033494 TBXAS1 6916 thromboxane A synthase 1 (platelet) cyclooxygenase pathway Biological process - EIF4A1 1973 eukaryotic translation initiation factor 4A1 organ regeneration Biological process - P2RX5 5026 purinergic receptor P2X, ligand gated ion channel, 5 response to ATP Biological process - CRMP1 1400 collapsin response mediator protein 1 spindle Cellular component - DNAAF2 55172 dynein, axonemal, assembly factor 2 protein binding Molecular function 23872636 ICAM1 3383 intercellular adhesion molecule 1 cellular response to lipopolysaccharide Biological process - SNX10 29887 sorting nexin 10 endosome Cellular component - TENM2 57451 teneurin transmembrane protein 2 axon guidance Biological process 21724987 AXIN2 8313 axin 2 regulation of mismatch repair Biological process 11017067 CASQ1 844 calsequestrin 1 (fast-twitch, skeletal muscle) sarcoplasmic reticulum membrane Cellular component - HUWE1 10075 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase protein polyubiquitination Biological process 15989957 CRBN 51185 cereblon metal ion binding Molecular function - FGF8 2253 fibroblast growth factor 8 (androgen-induced) forebrain morphogenesis Biological process - ADAM17 6868 ADAM metallopeptidase domain 17 PDZ domain binding Molecular function 12207026 MADCAM1 8174 mucosal vascular addressin cell adhesion molecule 1 extracellular matrix organization Biological process - DZANK1 55184 double zinc ribbon and ankyrin repeat domains 1 zinc ion binding Molecular function - PRKD1 5587 protein kinase D1 cytosol Cellular component - POU2F3 25833 POU class 2 homeobox 3 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Molecular function 12624109 TH 7054 tyrosine hydroxylase cellular response to drug Biological process - LOC440786 440786 uncharacterized LOC440786 immune response Biological process 4596149 SIPA1 6494 signal-induced proliferation-associated 1 Golgi apparatus Cellular component - AGTR2 186 angiotensin II receptor, type 2 cerebellar cortex development Biological process - VRK2 7444 vaccinia related kinase 2 regulation of cell shape Biological process - MAP2K2 5605 mitogen-activated protein kinase kinase 2 extracellular region Cellular component 8388392 CHST3 9469 carbohydrate (chondroitin 6) sulfotransferase 3 chondroitin sulfate biosynthetic process Biological process - OR2B2 81697 olfactory receptor, family 2, subfamily B, member 2 detection of chemical stimulus involved in sensory perception of smell Biological process - CADPS 8618 Ca++-dependent secretion activator protein binding Molecular function 17984325 RPS17 6218 ribosomal protein S17 ribosomal small subunit assembly Biological process - KIF14 9928 kinesin family member 14 cell proliferation in forebrain Biological process - COQ6 51004 coenzyme Q6 monooxygenase small molecule metabolic process Biological process - NRG1 3084 neuregulin 1 transcription cofactor activity Molecular function 15073182 OR10A3 26496 olfactory receptor, family 10, subfamily A, member 3 sensory perception of smell Biological process 1370859 ALS2 57679 amyotrophic lateral sclerosis 2 (juvenile) protein localization Biological process - SRC 6714 SRC proto-oncogene, non-receptor tyrosine kinase bone resorption Biological process - SUN5 140732 Sad1 and UNC84 domain containing 5 molecular_function Molecular function - SOD1 6647 superoxide dismutase 1, soluble cell aging Biological process 12871978 DRGX 644168 dorsal root ganglia homeobox dorsal spinal cord development Biological process - FGL1 2267 fibrinogen-like 1 adipose tissue development Biological process - RAB29 8934 RAB29, member RAS oncogene family positive regulation of intracellular protein transport Biological process 24788816 RAB38 23682 RAB38, member RAS oncogene family endoplasmic reticulum Cellular component - ERBB2 2064 erb-b2 receptor tyrosine kinase 2 protein C-terminus binding Molecular function 15520177 UBB 7314 ubiquitin B negative regulation of canonical Wnt signaling pathway Biological process - GSK3B 2932 glycogen synthase kinase 3 beta NF-kappaB binding Molecular function 15465828 ATP6V0D1 9114 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 transmembrane transport Biological process - MANF 7873 mesencephalic astrocyte-derived neurotrophic factor vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure Biological process - CGA 1081 glycoprotein hormones, alpha polypeptide positive regulation of cell migration Biological process 20613903 RGCC 28984 regulator of cell cycle protein binding Molecular function 19162005 MESP1 55897 mesoderm posterior basic helix-loop-helix transcription factor 1 cardiac ventricle formation Biological process 18297060 ST6GAL2 84620 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 growth Biological process 12235148 TGFBI 7045 transforming growth factor, beta-induced, 68kDa negative regulation of cell adhesion Biological process 8024701 OR51E2 81285 olfactory receptor, family 51, subfamily E, member 2 steroid hormone receptor activity Molecular function 19389702 TIMP1 7076 TIMP metallopeptidase inhibitor 1 metalloendopeptidase inhibitor activity Molecular function 12714508 LSM3 27258 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) gene expression Biological process - BMP8A 353500 bone morphogenetic protein 8a regulation of energy homeostasis Biological process 22579288 METTL10 399818 methyltransferase like 10 cytoplasm Cellular component - AFF1 4299 AF4/FMR2 family, member 1 transcription elongation factor complex Cellular component 22195968 NKD2 85409 naked cuticle homolog 2 (Drosophila) negative regulation of canonical Wnt signaling pathway Biological process 15687260 SARNP 84324 SAP domain containing ribonucleoprotein poly(A) RNA binding Molecular function 22658674 XXYLT1 152002 xyloside xylosyltransferase 1 transferase activity, transferring pentosyl groups Molecular function - IL23R 149233 interleukin 23 receptor inflammatory response Biological process - BMPR1B 658 bone morphogenetic protein receptor, type IB dorsal/ventral pattern formation Biological process - SLC24A1 9187 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 response to light intensity Biological process 9856482 MMP20 9313 matrix metallopeptidase 20 collagen catabolic process Biological process - RIPK2 8767 receptor-interacting serine-threonine kinase 2 toll-like receptor 3 signaling pathway Biological process - CA3 761 carbonic anhydrase III cytosol Cellular component - MAN1A1 4121 mannosidase, alpha, class 1A, member 1 integral component of membrane Cellular component - KLC1 3831 kinesin light chain 1 microtubule-based movement Biological process - STARD8 9754 StAR-related lipid transfer (START) domain containing 8 lipid binding Molecular function - UBA52 7311 ubiquitin A-52 residue ribosomal protein fusion product 1 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle Biological process - PTK2 5747 protein tyrosine kinase 2 cytosol Cellular component - BRCA1 672 breast cancer 1, early onset regulation of cell proliferation Biological process 10918303 HIST1H4D 8360 histone cluster 1, H4d DNA methylation on cytosine Biological process - ERVK-16 100616411 endogenous retrovirus group K, member 16 mRNA transport Biological process - PLAT 5327 plasminogen activator, tissue cellular protein modification process Biological process 3087818 NR2C1 7181 nuclear receptor subfamily 2, group C, member 1 steroid hormone mediated signaling pathway Biological process - HOXA1 3198 homeobox A1 facial nucleus development Biological process - P2RX7 5027 purinergic receptor P2X, ligand gated ion channel, 7 positive regulation of mitochondrial depolarization Biological process - CDH1 999 cadherin 1, type 1, E-cadherin (epithelial) lateral plasma membrane Cellular component 16338932 ZKSCAN8 7745 zinc finger with KRAB and SCAN domains 8 regulation of transcription, DNA-templated Biological process - SRSF3 6428 serine/arginine-rich splicing factor 3 gene expression Biological process - CTNNB1 1499 catenin (cadherin-associated protein), beta 1, 88kDa embryonic hindlimb morphogenesis Biological process - BOC 91653 BOC cell adhesion associated, oncogene regulated integral component of membrane Cellular component - ATRN 8455 attractin inflammatory response Biological process - B4GALT4 8702 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 small molecule metabolic process Biological process - ZDHHC20 253832 zinc finger, DHHC-type containing 20 membrane Cellular component 19946888 PPL 5493 periplakin mitochondrion Cellular component - AR 367 androgen receptor nucleoplasm Cellular component - ACVR1B 91 activin A receptor, type IB positive regulation of pathway-restricted SMAD protein phosphorylation Biological process - CLEC5A 23601 C-type lectin domain family 5, member A innate immune response Biological process - CYLD 1540 cylindromatosis (turban tumor syndrome) cytosol Cellular component - NPAP1 23742 nuclear pore associated protein 1 nuclear inner membrane Cellular component - PPP1R12A 4659 protein phosphatase 1, regulatory subunit 12A protein kinase binding Molecular function 18477460 ZNF324 25799 zinc finger protein 324 metal ion binding Molecular function - CAMKK2 10645 calcium/calmodulin-dependent protein kinase kinase 2, beta protein phosphorylation Biological process 11395482 NKX2-2 4821 NK2 homeobox 2 sequence-specific DNA binding transcription factor activity Molecular function - ANKRD1 27063 ankyrin repeat domain 1 (cardiac muscle) response to muscle stretch Biological process 19608030 PSMD2 5708 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 antigen processing and presentation of peptide antigen via MHC class I Biological process - ERAP1 51752 endoplasmic reticulum aminopeptidase 1 extracellular exosome Cellular component 19199708 UCN 7349 urocortin positive regulation of cAMP biosynthetic process Biological process - SLC35F2 54733 solute carrier family 35, member F2 integral component of membrane Cellular component - NME7 29922 NME/NM23 family member 7 determination of left/right symmetry Biological process - ARL6IP5 10550 ADP-ribosylation factor-like 6 interacting protein 5 positive regulation of apoptotic process Biological process 18387645 TMEM201 199953 transmembrane protein 201 actin filament binding Molecular function - KIDINS220 57498 kinase D-interacting substrate, 220kDa regulation of protein kinase activity Biological process - LY6D 8581 lymphocyte antigen 6 complex, locus D membrane Cellular component 7790363 TDRD1 56165 tudor domain containing 1 multicellular organismal development Biological process - PTPN5 84867 protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) phosphotyrosine binding Molecular function 16441242 PTPRM 5797 protein tyrosine phosphatase, receptor type, M positive regulation of vasodilation Biological process - CACNA1C 775 calcium channel, voltage-dependent, L type, alpha 1C subunit voltage-gated calcium channel complex Cellular component 12130699 PVRL2 5819 poliovirus receptor-related 2 (herpesvirus entry mediator B) establishment of mitochondrion localization Biological process - LAMP5 24141 lysosomal-associated membrane protein family, member 5 growth cone membrane Cellular component - GRIN2A 2903 glutamate receptor, ionotropic, N-methyl D-aspartate 2A zinc ion binding Molecular function - KCNIP3 30818 Kv channel interacting protein 3, calsenilin protein binding Molecular function 16189514 ULK2 9706 unc-51 like autophagy activating kinase 2 protein autophosphorylation Biological process 18936157 SNX1 6642 sorting nexin 1 transferrin receptor binding Molecular function 9819414 NR2E3 10002 nuclear receptor subfamily 2, group E, member 3 steroid hormone mediated signaling pathway Biological process - IGHG4 3503 immunoglobulin heavy constant gamma 4 (G4m marker) extracellular region Cellular component - KDM1A 23028 lysine (K)-specific demethylase 1A histone demethylase activity (H3-K4 specific) Molecular function 15620353 VNN1 8876 vanin 1 acute inflammatory response Biological process 14966568 BAZ1B 9031 bromodomain adjacent to zinc finger domain, 1B ATP binding Molecular function - SNTA1 6640 syntrophin, alpha 1 neuromuscular junction Cellular component - CYP2A6 1548 cytochrome P450, family 2, subfamily A, polypeptide 6 xenobiotic metabolic process Biological process - DMD 1756 dystrophin regulation of heart rate Biological process 19027585 TUBG2 27175 tubulin, gamma 2 microtubule cytoskeleton Cellular component 10903841 OR8I2 120586 olfactory receptor, family 8, subfamily I, member 2 olfactory receptor activity Molecular function - PCYT1A 5130 phosphate cytidylyltransferase 1, choline, alpha choline-phosphate cytidylyltransferase activity Molecular function - MID1IP1 58526 MID1 interacting protein 1 positive regulation of fatty acid biosynthetic process Biological process - HIP1 3092 huntingtin interacting protein 1 activation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 11788820 PAPPA-AS1 493913 PAPPA antisense RNA 1 endoplasmic reticulum membrane Cellular component - CHMP4C 92421 charged multivesicular body protein 4C nucleus organization Biological process 20616062 PIN4 5303 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 rRNA processing Biological process 19369196 TMSB15B 286527 thymosin beta 15B cytoplasm Cellular component - HBA2 3040 hemoglobin, alpha 2 peroxidase activity Molecular function 19740759 NLGN3 54413 neuroligin 3 visual learning Biological process - KMT2A 4297 lysine (K)-specific methyltransferase 2A chromatin organization Biological process - HMGA2 8091 high mobility group AT-hook 2 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function 14627817 POLDIP3 84271 polymerase (DNA-directed), delta interacting protein 3 nucleotide binding Molecular function - TCEAL2 140597 transcription elongation factor A (SII)-like 2 regulation of transcription, DNA-templated Biological process - ZRANB3 84083 zinc finger, RAN-binding domain containing 3 nuclear replication fork Cellular component 22704558 CHD5 26038 chromodomain helicase DNA binding protein 5 NuRD complex Cellular component - FAF2 23197 Fas associated factor family member 2 ubiquitin binding Molecular function 18775313 PARVG 64098 parvin, gamma cytoplasm Cellular component - WRN 7486 Werner syndrome, RecQ helicase-like DNA metabolic process Biological process 16622405 ZNF728 388523 zinc finger protein 728 intracellular Cellular component - OGT 8473 O-linked N-acetylglucosamine (GlcNAc) transferase nucleus Cellular component 21285374 F2RL1 2150 coagulation factor II (thrombin) receptor-like 1 positive regulation of cytokine secretion involved in immune response Biological process 11441110 GAK 2580 cyclin G associated kinase clathrin-mediated endocytosis Biological process - ZNF812 729648 zinc finger protein 812 transcription, DNA-templated Biological process - P2RX7 5027 purinergic receptor P2X, ligand gated ion channel, 7 positive regulation of interleukin-1 alpha secretion Biological process - GFPT1 2673 glutamine--fructose-6-phosphate transaminase 1 post-translational protein modification Biological process - CENPL 91687 centromere protein L CENP-A containing nucleosome assembly Biological process - JARID2 3720 jumonji, AT rich interactive domain 2 liver development Biological process - GTF2H2 2966 general transcription factor IIH, polypeptide 2, 44kDa DNA repair Biological process - FGF19 9965 fibroblast growth factor 19 neural crest cell migration Biological process - KLK3 354 kallikrein-related peptidase 3 protein binding Molecular function 1725227 RBM15B 29890 RNA binding motif protein 15B viral process Biological process - PHF13 148479 PHD finger protein 13 nucleus Cellular component 19638409 PTTG1IP 754 pituitary tumor-transforming 1 interacting protein negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator Biological process 24506068 HSD17B4 3295 hydroxysteroid (17-beta) dehydrogenase 4 membrane Cellular component 16210410 FABP3 2170 fatty acid binding protein 3, muscle and heart response to insulin Biological process - KIF3C 3797 kinesin family member 3C cytosol Cellular component - BCL2L1 598 BCL2-like 1 negative regulation of anoikis Biological process 15006356 DDX58 23586 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 cytoplasm Cellular component - APBB1 322 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) transcription factor binding Molecular function - UCP3 7352 uncoupling protein 3 (mitochondrial, proton carrier) lipid metabolic process Biological process 10935638 AKT1 207 v-akt murine thymoma viral oncogene homolog 1 intrinsic apoptotic signaling pathway Biological process - AP3D1 8943 adaptor-related protein complex 3, delta 1 subunit anterograde synaptic vesicle transport Biological process - ING4 51147 inhibitor of growth family, member 4 protein acetylation Biological process 12750254 ST6GALNAC2 10610 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 sialyltransferase activity Molecular function - PIN4 5303 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 protein peptidyl-prolyl isomerization Biological process - PDLIM2 64236 PDZ and LIM domain 2 (mystique) muscle alpha-actinin binding Molecular function - ATP9B 374868 ATPase, class II, type 9B magnesium ion binding Molecular function - TH 7054 tyrosine hydroxylase catecholamine biosynthetic process Biological process - UBE2B 7320 ubiquitin-conjugating enzyme E2B protein stabilization Biological process 18339854 RDM1 201299 RAD52 motif containing 1 Cajal body Cellular component - USP19 10869 ubiquitin specific peptidase 19 positive regulation of cell cycle process Biological process - OR9A2 135924 olfactory receptor, family 9, subfamily A, member 2 detection of chemical stimulus involved in sensory perception of smell Biological process - PIK3C3 5289 phosphatidylinositol 3-kinase, catalytic subunit type 3 protein kinase activity Molecular function - CD86 942 CD86 molecule response to drug Biological process - CRHBP 1393 corticotropin releasing hormone binding protein protein binding Molecular function 18234674 TIPIN 54962 TIMELESS interacting protein nucleoplasm Cellular component - IFIH1 64135 interferon induced with helicase C domain 1 protein binding Molecular function 16127453 TRAF5 7188 TNF receptor-associated factor 5 apoptotic process Biological process - FBLN2 2199 fibulin 2 proteinaceous extracellular matrix Cellular component - SLN 6588 sarcolipin negative regulation of catalytic activity Biological process 12032137 TPD52L1 7164 tumor protein D52-like 1 regulation of cysteine-type endopeptidase activity involved in apoptotic process Biological process 14761963 HYAL2 8692 hyaluronoglucosaminidase 2 Golgi membrane Cellular component 21740893 PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta adaptive immune response Biological process 17290298 FAU 2197 Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed cellular_component Cellular component - CLCN3 1182 chloride channel, voltage-sensitive 3 early endosome membrane Cellular component - RASGRP3 25780 RAS guanyl releasing protein 3 (calcium and DAG-regulated) MAPK cascade Biological process 10934204 EMX1 2016 empty spiracles homeobox 1 brain morphogenesis Biological process - IGSF3 3321 immunoglobulin superfamily, member 3 cell surface Cellular component 19581412 NDNF 79625 neuron-derived neurotrophic factor peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan Biological process - PAPSS1 9061 3'-phosphoadenosine 5'-phosphosulfate synthase 1 sulfate adenylyltransferase (ATP) activity Molecular function - SURF2 6835 surfeit 2 biological_process Biological process - RNASEL 6041 ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) negative regulation of viral genome replication Biological process 19923450 CTDSP1 58190 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 negative regulation of G1/S transition of mitotic cell cycle Biological process - NHP2L1 4809 NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae) protein binding Molecular function 17412961 PLK1 5347 polo-like kinase 1 mitotic cell cycle Biological process - CFP 5199 complement factor properdin extracellular matrix Cellular component 20551380 RPS28 6234 ribosomal protein S28 viral transcription Biological process - PLCB2 5330 phospholipase C, beta 2 lipid catabolic process Biological process - GSX1 219409 GS homeobox 1 positive regulation of transcription from RNA polymerase II promoter Biological process 11731616 CDK12 51755 cyclin-dependent kinase 12 RNA splicing Biological process - OR1L8 138881 olfactory receptor, family 1, subfamily L, member 8 G-protein coupled receptor signaling pathway Biological process - TDG 6996 thymine-DNA glycosylase damaged DNA binding Molecular function 9489705 BIN1 274 bridging integrator 1 protein heterodimerization activity Molecular function - RYR2 6262 ryanodine receptor 2 (cardiac) calcium-release channel activity Molecular function 17921453 CRY2 1408 cryptochrome circadian clock 2 protein import into nucleus Biological process - PCF11 51585 PCF11 cleavage and polyadenylation factor subunit nucleoplasm Cellular component - CARD18 59082 caspase recruitment domain family, member 18 regulation of apoptotic process Biological process - TBL3 10607 transducin (beta)-like 3 nucleus Cellular component - ZBED9 114821 zinc finger, BED-type containing 9 sequence-specific DNA binding transcription factor activity Molecular function - IL1RN 3557 interleukin 1 receptor antagonist female pregnancy Biological process - PRPF4 9128 pre-mRNA processing factor 4 U4/U6 x U5 tri-snRNP complex Cellular component - WDTC1 23038 WD and tetratricopeptide repeats 1 multicellular organism growth Biological process - USP30 84749 ubiquitin specific peptidase 30 regulation of proteasomal protein catabolic process Biological process - FGFR3 2261 fibroblast growth factor receptor 3 protein autophosphorylation Biological process 11294897 ZSCAN25 221785 zinc finger and SCAN domain containing 25 metal ion binding Molecular function - MST1R 4486 macrophage stimulating 1 receptor macrophage colony-stimulating factor receptor activity Molecular function 9045873 ATP6V1B2 526 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 cellular iron ion homeostasis Biological process - CTSH 1512 cathepsin H kininogen binding Molecular function - IGLC6 3542 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene) complement activation Biological process - DDO 8528 D-aspartate oxidase receptor binding Molecular function 20178365 C14orf2 9556 chromosome 14 open reading frame 2 cellular_component Cellular component - PTEN 5728 phosphatase and tensin homolog cell projection Cellular component 10760291 PTPN11 5781 protein tyrosine phosphatase, non-receptor type 11 ERBB signaling pathway Biological process 15133037 MAGED1 9500 melanoma antigen family D1 regulation of apoptotic process Biological process 15930293 STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) growth hormone receptor signaling pathway Biological process 10925297 MAB21L1 4081 mab-21-like 1 (C. elegans) nucleus Cellular component - TBP 6908 TATA box binding protein sequence-specific DNA binding transcription factor activity Molecular function - TXNL1 9352 thioredoxin-like 1 cell redox homeostasis Biological process - TCEA2 6919 transcription elongation factor A (SII), 2 zinc ion binding Molecular function - TGIF1 7050 TGFB-induced factor homeobox 1 chromatin binding Molecular function - C9orf135 138255 chromosome 9 open reading frame 135 integral component of membrane Cellular component - SYT10 341359 synaptotagmin X protein heterodimerization activity Molecular function - SDHC 6391 succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa mitochondrial electron transport, succinate to ubiquinone Biological process - TESC 54997 tescalcin calcium ion binding Molecular function 11696366 SCAMP2 10066 secretory carrier membrane protein 2 protein transport Biological process 15840657 AKAP13 11214 A kinase (PRKA) anchor protein 13 neurotrophin TRK receptor signaling pathway Biological process - HEXA 3073 hexosaminidase A (alpha polypeptide) glycosphingolipid metabolic process Biological process - PCDHB4 56131 protocadherin beta 4 intermediate filament cytoskeleton Cellular component - PPM1K 152926 protein phosphatase, Mg2+/Mn2+ dependent, 1K metal ion binding Molecular function - ADAM8 101 ADAM metallopeptidase domain 8 integral component of plasma membrane Cellular component 18397961 TRIM58 25893 tripartite motif containing 58 intracellular Cellular component - ACAT1 38 acetyl-CoA acetyltransferase 1 response to hormone Biological process - SUZ12 23512 SUZ12 polycomb repressive complex 2 subunit sequence-specific DNA binding Molecular function - NPY5R 4889 neuropeptide Y receptor Y5 G-protein coupled receptor signaling pathway Biological process 8824284 POR 5447 P450 (cytochrome) oxidoreductase electron carrier activity Molecular function - PRTFDC1 56952 phosphoribosyl transferase domain containing 1 hypoxanthine phosphoribosyltransferase activity Molecular function 21054786 PAPOLA 10914 poly(A) polymerase alpha nucleoplasm Cellular component - PARN 5073 poly(A)-specific ribonuclease RNA modification Biological process 9736620 FMO2 2327 flavin containing monooxygenase 2 (non-functional) flavin adenine dinucleotide binding Molecular function - RCOR3 55758 REST corepressor 3 regulation of transcription, DNA-templated Biological process - FGFR1 2260 fibroblast growth factor receptor 1 middle ear morphogenesis Biological process - HDX 139324 highly divergent homeobox DNA binding Molecular function - NR4A2 4929 nuclear receptor subfamily 4, group A, member 2 response to inorganic substance Biological process - NOX5 79400 NADPH oxidase, EF-hand calcium binding domain 5 calcium ion binding Molecular function - OSGEP 55644 O-sialoglycoprotein endopeptidase EKC/KEOPS complex Cellular component - AGO4 192670 argonaute RISC catalytic component 4 pre-miRNA processing Biological process 19966796 DHCR24 1718 24-dehydrocholesterol reductase cytosol Cellular component - DAB2IP 153090 DAB2 interacting protein vascular endothelial growth factor receptor 2 binding Molecular function 19033661 CDKN1C 1028 cyclin-dependent kinase inhibitor 1C (p57, Kip2) protein binding Molecular function 16289477 HLTF 6596 helicase-like transcription factor protein polyubiquitination Biological process - CD300LB 124599 CD300 molecule-like family member b integral component of membrane Cellular component - PDIA6 10130 protein disulfide isomerase family A, member 6 cell redox homeostasis Biological process - NCOA2 10499 nuclear receptor coactivator 2 positive regulation of transcription from RNA polymerase II promoter Biological process - NAT8B 51471 N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) integral component of membrane Cellular component 11397015 SCLY 51540 selenocysteine lyase pyridoxal phosphate binding Molecular function - AQP1 358 aquaporin 1 (Colton blood group) secretory granule organization Biological process - CADPS2 93664 Ca++-dependent secretion activator 2 presynaptic membrane Cellular component - SRGAP2C 653464 SLIT-ROBO Rho GTPase activating protein 2C negative regulation of filopodium assembly Biological process 22559944 MGLL 11343 monoglyceride lipase regulation of axon extension Biological process - DRD4 1815 dopamine receptor D4 cell cortex Cellular component - EZR 7430 ezrin astrocyte projection Cellular component - ANKRD46 157567 ankyrin repeat domain 46 integral component of membrane Cellular component - NCBP2 22916 nuclear cap binding protein subunit 2, 20kDa termination of RNA polymerase II transcription Biological process - MSX1 4487 msh homeobox 1 epithelial to mesenchymal transition involved in endocardial cushion formation Biological process - IGBP1 3476 immunoglobulin (CD79A) binding protein 1 positive regulation of dephosphorylation Biological process - ZIK1 284307 zinc finger protein interacting with K protein 1 transcription, DNA-templated Biological process - ACSM1 116285 acyl-CoA synthetase medium-chain family member 1 energy derivation by oxidation of organic compounds Biological process 11470804 HOMER1 9456 homer scaffolding protein 1 behavioral response to cocaine Biological process - VPS4B 9525 vacuolar protein sorting 4 homolog B (S. cerevisiae) cell separation after cytokinesis Biological process 20616062 SOS1 6654 son of sevenless homolog 1 (Drosophila) plasma membrane Cellular component - FRMPD3 84443 FERM and PDZ domain containing 3 cytoskeleton Cellular component - CHMP4B 128866 charged multivesicular body protein 4B extracellular exosome Cellular component 19056867 ABCG2 9429 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) nucleoplasm Cellular component - PDCD6IP 10015 programmed cell death 6 interacting protein focal adhesion Cellular component 21423176 NLRC4 58484 NLR family, CARD domain containing 4 activation of innate immune response Biological process - TMEM132A 54972 transmembrane protein 132A extracellular exosome Cellular component 23533145 RNF126 55658 ring finger protein 126 protein monoubiquitination Biological process 23277564 OVCH1 341350 ovochymase 1 extracellular region Cellular component - THEM4 117145 thioesterase superfamily member 4 neurotrophin TRK receptor signaling pathway Biological process - NOC2L 26155 nucleolar complex associated 2 homolog (S. cerevisiae) transcription, DNA-templated Biological process - AIF1 199 allograft inflammatory factor 1 Rac protein signal transduction Biological process - GRK5 2869 G protein-coupled receptor kinase 5 termination of G-protein coupled receptor signaling pathway Biological process - SMAD3 4088 SMAD family member 3 evasion or tolerance of host defenses by virus Biological process 15334054 BCL2 596 B-cell CLL/lymphoma 2 positive regulation of cell growth Biological process 8022822 INSL6 11172 insulin-like 6 extracellular region Cellular component - NANS 54187 N-acetylneuraminic acid synthase post-translational protein modification Biological process - B4GAT1 11041 beta-1,4-glucuronyltransferase 1 extracellular exosome Cellular component 23376485 MYOD1 4654 myogenic differentiation 1 myotube differentiation involved in skeletal muscle regeneration Biological process - CD86 942 CD86 molecule intracellular membrane-bounded organelle Cellular component - RGS14 10636 regulator of G-protein signaling 14 regulation of DNA-templated transcription in response to stress Biological process - USP1 7398 ubiquitin specific peptidase 1 protein binding Molecular function 18082604 C19orf70 125988 chromosome 19 open reading frame 70 mitochondrion Cellular component - NCOA6 23054 nuclear receptor coactivator 6 DNA replication Biological process 11443112 KRT20 54474 keratin 20, type I intermediate filament Cellular component 8359595 STAT1 6772 signal transducer and activator of transcription 1, 91kDa response to hydrogen peroxide Biological process - GABRA5 2558 gamma-aminobutyric acid (GABA) A receptor, alpha 5 signal transduction Biological process 1321750 PROKR1 10887 prokineticin receptor 1 neuropeptide Y receptor activity Molecular function - TUBA4A 7277 tubulin, alpha 4a GTPase activity Molecular function - FOXJ1 2302 forkhead box J1 glomerular parietal epithelial cell development Biological process 9530170 LAMA1 284217 laminin, alpha 1 cell adhesion Biological process - NODAL 4838 nodal growth differentiation factor negative regulation of androgen receptor signaling pathway Biological process 21656830 NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 cellular response to interleukin-6 Biological process 22357537 ZNF501 115560 zinc finger protein 501 transcription, DNA-templated Biological process - SF1 7536 splicing factor 1 spliceosomal complex assembly Biological process 8752089 RPL37A 6168 ribosomal protein L37a extracellular exosome Cellular component 20458337 GAS2L3 283431 growth arrest-specific 2 like 3 cytoplasm Cellular component - ST3GAL2 6483 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 protein N-linked glycosylation via asparagine Biological process - OR4A5 81318 olfactory receptor, family 4, subfamily A, member 5 olfactory receptor activity Molecular function - MT1X 4501 metallothionein 1X cytoplasm Cellular component 8619255 ZC3HAV1 56829 zinc finger CCCH-type, antiviral 1 positive regulation of interferon-beta production Biological process 21102435 IL6 3569 interleukin 6 positive regulation of immunoglobulin secretion Biological process 3491322 PABPC1 26986 poly(A) binding protein, cytoplasmic 1 mRNA stabilization Biological process 11997512 SLC6A11 6538 solute carrier family 6 (neurotransmitter transporter), member 11 gamma-aminobutyric acid:sodium symporter activity Molecular function - ACOX2 8309 acyl-CoA oxidase 2, branched chain peroxisome Cellular component 2079609 CYSLTR1 10800 cysteinyl leukotriene receptor 1 defense response Biological process 10391245 FOXM1 2305 forkhead box M1 nucleus Cellular component - SOX5 6660 SRY (sex determining region Y)-box 5 cell fate commitment Biological process - FGF8 2253 fibroblast growth factor 8 (androgen-induced) odontogenesis Biological process 17394220 ASUN 55726 asunder spermatogenesis regulator mitotic spindle organization Biological process 23097494 JARID2 3720 jumonji, AT rich interactive domain 2 stem cell differentiation Biological process - RIPK2 8767 receptor-interacting serine-threonine kinase 2 toll-like receptor 4 signaling pathway Biological process - FPGS 2356 folylpolyglutamate synthase mitochondrial inner membrane Cellular component - FOXP3 50943 forkhead box P3 positive regulation of transcription from RNA polymerase II promoter Biological process 19276356 EIF2B4 8890 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa oligodendrocyte development Biological process 15217090 SCNN1G 6340 sodium channel, non voltage gated 1 gamma subunit response to stimulus Biological process - ITGB1 3688 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) recycling endosome Cellular component - KCNK10 54207 potassium channel, two pore domain subfamily K, member 10 potassium ion transmembrane transport Biological process - KLHL12 59349 kelch-like family member 12 protein binding Molecular function 16189514 NFE2L1 4779 nuclear factor, erythroid 2-like 1 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription Molecular function - PLCB4 5332 phospholipase C, beta 4 cytosol Cellular component - PRDX3 10935 peroxiredoxin 3 peptidyl-cysteine oxidation Biological process 21850687 DDX23 9416 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 RNA splicing, via transesterification reactions Biological process 9409622 EPHA6 285220 EPH receptor A6 cellular_component Cellular component - B4GALT2 8704 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 small molecule metabolic process Biological process - MAPRE1 22919 microtubule-associated protein, RP/EB family, member 1 protein C-terminus binding Molecular function 7606712 ABCD4 5826 ATP-binding cassette, sub-family D (ALD), member 4 ATPase activity, coupled to transmembrane movement of substances Molecular function 9266848 SUPT5H 6829 suppressor of Ty 5 homolog (S. cerevisiae) negative regulation of transcription from RNA polymerase II promoter Biological process 10075709 ALG2 85365 ALG2, alpha-1,3/1,6-mannosyltransferase glycolipid 6-alpha-mannosyltransferase activity Molecular function - NRAS 4893 neuroblastoma RAS viral (v-ras) oncogene homolog extracellular exosome Cellular component 20458337 DNMT3L 29947 DNA (cytosine-5-)-methyltransferase 3-like gene expression Biological process - MGA 23269 MGA, MAX dimerization protein transcription factor complex Cellular component - CD86 942 CD86 molecule innate immune response Biological process - TLN2 83660 talin 2 plasma membrane Cellular component - AKT1 207 v-akt murine thymoma viral oncogene homolog 1 phosphorylation Biological process 20333297 PEX1 5189 peroxisomal biogenesis factor 1 ATP binding Molecular function 16854980 PDIA3 2923 protein disulfide isomerase family A, member 3 oxidation-reduction process Biological process 22013210 NKIRAS1 28512 NFKB inhibitor interacting Ras-like 1 I-kappaB kinase/NF-kappaB signaling Biological process 10657303 EPHA3 2042 EPH receptor A3 fasciculation of sensory neuron axon Biological process - TIMM9 26520 translocase of inner mitochondrial membrane 9 homolog (yeast) protein import into mitochondrial inner membrane Biological process 14726512 UBE2S 27338 ubiquitin-conjugating enzyme E2S ubiquitin conjugating enzyme activity Molecular function 21376237 NDUFS3 4722 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) mitochondrial respiratory chain complex I Cellular component 9878551 PDILT 204474 protein disulfide isomerase-like, testis expressed spermatid development Biological process - MRPL13 28998 mitochondrial ribosomal protein L13 mitochondrial large ribosomal subunit Cellular component 11279069 CLIP1 6249 CAP-GLY domain containing linker protein 1 cytoplasmic microtubule Cellular component - HES2 54626 hes family bHLH transcription factor 2 nucleus Cellular component - CLCN4 1183 chloride channel, voltage-sensitive 4 early endosome membrane Cellular component - TBR1 10716 T-box, brain, 1 commitment of neuronal cell to specific neuron type in forebrain Biological process - VPS33A 65082 vacuolar protein sorting 33 homolog A (S. cerevisiae) lysosome localization Biological process 15790593 GPR139 124274 G protein-coupled receptor 139 integral component of membrane Cellular component - CAPN3 825 calpain 3, (p94) nucleus Cellular component 19386580 CCDC151 115948 coiled-coil domain containing 151 centriole Cellular component - MOV10 4343 Mov10 RISC complex RNA helicase cytoplasmic mRNA processing body Cellular component 16289642 CTBS 1486 chitobiase, di-N-acetyl- lysosome Cellular component - THAP11 57215 THAP domain containing 11 cytoplasm Cellular component - APOA4 337 apolipoprotein A-IV retinoid metabolic process Biological process - CKAP5 9793 cytoskeleton associated protein 5 mitotic cell cycle Biological process - EGFL6 25975 EGF-like-domain, multiple 6 basement membrane Cellular component - HDAC3 8841 histone deacetylase 3 negative regulation of transcription, DNA-templated Biological process 16924111 DSG2 1829 desmoglein 2 maternal process involved in female pregnancy Biological process - PXDN 7837 peroxidasin response to oxidative stress Biological process - CATIP 375307 ciliogenesis associated TTC17 interacting protein calmodulin binding Molecular function - CCDC77 84318 coiled-coil domain containing 77 centrosome Cellular component 21399614 BTN2A2 10385 butyrophilin, subfamily 2, member A2 extracellular exosome Cellular component 23376485 IL10 3586 interleukin 10 cellular response to lipopolysaccharide Biological process 14971032 TNFRSF10C 8794 tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain signal transduction Biological process 9314565 PSAT1 29968 phosphoserine aminotransferase 1 cellular amino acid biosynthetic process Biological process - PEX14 5195 peroxisomal biogenesis factor 14 microtubule binding Molecular function 21525035 PDCD6 10016 programmed cell death 6 endosome Cellular component - CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta negative regulation of neuron apoptotic process Biological process - STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor) positive regulation of Notch signaling pathway Biological process - PAFAH2 5051 platelet-activating factor acetylhydrolase 2, 40kDa lipid metabolic process Biological process 8955149 CSF1 1435 colony stimulating factor 1 (macrophage) positive regulation of microglial cell migration Biological process 19100238 EPN2 22905 epsin 2 intracellular membrane-bounded organelle Cellular component - CHCHD5 84269 coiled-coil-helix-coiled-coil-helix domain containing 5 aerobic respiration Biological process - ARHGEF1 9138 Rho guanine nucleotide exchange factor (GEF) 1 GTPase activator activity Molecular function - MSR1 4481 macrophage scavenger receptor 1 protein binding Molecular function 17237231 ATOH1 474 atonal homolog 1 (Drosophila) central nervous system development Biological process 8872459 CDK15 65061 cyclin-dependent kinase 15 protein phosphorylation Biological process - RAB24 53917 RAB24, member RAS oncogene family intracellular protein transport Biological process - PACSIN2 11252 protein kinase C and casein kinase substrate in neurons 2 membrane-bounded vesicle Cellular component - ITGB2 3689 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) membrane Cellular component 19946888 BDH2 56898 3-hydroxybutyrate dehydrogenase, type 2 mitochondrion Cellular component 16380372 AMPD1 270 adenosine monophosphate deaminase 1 purine-containing compound salvage Biological process - DMRTA2 63950 DMRT-like family A2 skeletal muscle cell differentiation Biological process - WEE1 7465 WEE1 G2 checkpoint kinase cell division Biological process - CTH 1491 cystathionine gamma-lyase calmodulin binding Molecular function - PAX3 5077 paired box 3 muscle organ development Biological process - KATNA1 11104 katanin p60 (ATPase containing) subunit A 1 cytoplasm Cellular component 19261606 ATRN 8455 attractin extracellular space Cellular component 16502470 KRT9 3857 keratin 9, type I intermediate filament Cellular component - UBB 7314 ubiquitin B TRIF-dependent toll-like receptor signaling pathway Biological process - HDAC3 8841 histone deacetylase 3 negative regulation of apoptotic process Biological process 10777477 CHRNA1 1134 cholinergic receptor, nicotinic, alpha 1 (muscle) neuromuscular process Biological process 9546329 MTDH 92140 metadherin positive regulation of I-kappaB kinase/NF-kappaB signaling Biological process 16452207 EFNB1 1947 ephrin-B1 ephrin receptor binding Molecular function - MRPL13 28998 mitochondrial ribosomal protein L13 mitochondrial translational termination Biological process - PAFAH1B1 5048 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) microtubule binding Molecular function 10729324 EXT1 2131 exostosin glycosyltransferase 1 endoderm development Biological process - AGT 183 angiotensinogen (serpin peptidase inhibitor, clade A, member 8) positive regulation of NAD(P)H oxidase activity Biological process 17159080 STRAP 11171 serine/threonine kinase receptor associated protein maintenance of gastrointestinal epithelium Biological process 17929853 PIGU 128869 phosphatidylinositol glycan anchor biosynthesis, class U post-translational protein modification Biological process - LCE3A 353142 late cornified envelope 3A keratinization Biological process - INPP4A 3631 inositol polyphosphate-4-phosphatase, type I, 107kDa phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity Molecular function - PINK1 65018 PTEN induced putative kinase 1 nucleus Cellular component 24798695 SSTR1 6751 somatostatin receptor 1 cell surface receptor signaling pathway Biological process 1346068 RAMP1 10267 receptor (G protein-coupled) activity modifying protein 1 protein localization to plasma membrane Biological process 10882736 GTF2F1 2962 general transcription factor IIF, polypeptide 1, 74kDa nucleus Cellular component - UQCRFS1 7386 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 hydrogen ion transmembrane transport Biological process - KCNQ1 3784 potassium channel, voltage gated KQT-like subfamily Q, member 1 voltage-gated potassium channel activity Molecular function 16002409 ZNF362 149076 zinc finger protein 362 transcription, DNA-templated Biological process - WNT7B 7477 wingless-type MMTV integration site family, member 7B mammary gland epithelium development Biological process 8168088 RPL6 6128 ribosomal protein L6 viral process Biological process - OLA1 29789 Obg-like ATPase 1 protein binding Molecular function 22190034 PCBP1 5093 poly(rC) binding protein 1 membrane Cellular component 19946888 PTPN14 5784 protein tyrosine phosphatase, non-receptor type 14 regulation of protein export from nucleus Biological process 22948661 SLC52A3 113278 solute carrier family 52 (riboflavin transporter), member 3 apical plasma membrane Cellular component - REPS1 85021 RALBP1 associated Eps domain containing 1 plasma membrane Cellular component 20946875 ATP5B 506 ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide osteoblast differentiation Biological process 16210410 CEP250 11190 centrosomal protein 250kDa protein complex Cellular component 10880350 OR4F4 26682 olfactory receptor, family 4, subfamily F, member 4 integral component of membrane Cellular component - ATP1B1 481 ATPase, Na+/K+ transporting, beta 1 polypeptide sodium:potassium-exchanging ATPase activity Molecular function 10636900 MAPK9 5601 mitogen-activated protein kinase 9 protein targeting to mitochondrion Biological process - SEC24C 9632 SEC24 family member C cellular protein metabolic process Biological process - ADGRF3 165082 adhesion G protein-coupled receptor F3 G-protein coupled receptor activity Molecular function - ELK1 2002 ELK1, member of ETS oncogene family neuronal cell body Cellular component - GPR142 350383 G protein-coupled receptor 142 cytoplasm Cellular component - HDAC9 9734 histone deacetylase 9 repressing transcription factor binding Molecular function - WIPF1 7456 WAS/WASL interacting protein family, member 1 innate immune response Biological process - PRDX3 10935 peroxiredoxin 3 maternal placenta development Biological process - CASK 8573 calcium/calmodulin-dependent serine protein kinase (MAGUK family) nuclear matrix Cellular component 18664494 OR4P4 81300 olfactory receptor, family 4, subfamily P, member 4 plasma membrane Cellular component - PHOSPHO2 493911 phosphatase, orphan 2 phosphatase activity Molecular function - PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta protein phosphorylation Biological process 9113989 KLF4 9314 Kruppel-like factor 4 (gut) RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription Molecular function 21539536 CDK11B 984 cyclin-dependent kinase 11B regulation of mRNA processing Biological process 12501247 SIRT2 22933 sirtuin 2 tubulin deacetylase activity Molecular function 24177535 GPRASP1 9737 G protein-coupled receptor associated sorting protein 1 protein binding Molecular function 15086532 KIF1C 10749 kinesin family member 1C endoplasmic reticulum Cellular component 9685376 POLR2D 5433 polymerase (RNA) II (DNA directed) polypeptide D cytoplasmic mRNA processing body Cellular component - C1orf210 149466 chromosome 1 open reading frame 210 integral component of membrane Cellular component - COL9A3 1299 collagen, type IX, alpha 3 extracellular matrix structural constituent conferring tensile strength Molecular function 8660302 EXPH5 23086 exophilin 5 multivesicular body sorting pathway Biological process 19966785 RND3 390 Rho family GTPase 3 cell adhesion Biological process 9531558 BCAT1 586 branched chain amino-acid transaminase 1, cytosolic identical protein binding Molecular function - DERL1 79139 derlin 1 ER-associated ubiquitin-dependent protein catabolic process Biological process 22013210 CACNA1F 778 calcium channel, voltage-dependent, L type, alpha 1F subunit high voltage-gated calcium channel activity Molecular function - ANKDD1A 348094 ankyrin repeat and death domain containing 1A signal transduction Biological process - PIK3CD 5293 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta natural killer cell differentiation Biological process 20940048 WIPI1 55062 WD repeat domain, phosphoinositide interacting 1 IRE1-mediated unfolded protein response Biological process - CDC40 51362 cell division cycle 40 transcription from RNA polymerase II promoter Biological process - CHIT1 1118 chitinase 1 (chitotriosidase) extracellular space Cellular component 19725875 STXBP3 6814 syntaxin binding protein 3 specific granule Cellular component 18588921 PAK4 10298 p21 protein (Cdc42/Rac)-activated kinase 4 focal adhesion Cellular component 21423176 SKI 6497 SKI proto-oncogene cell motility Biological process 14583455 AKR1C1 1645 aldo-keto reductase family 1, member C1 protein homooligomerization Biological process 8486699 FYN 2534 FYN proto-oncogene, Src family tyrosine kinase ephrin receptor binding Molecular function 10498895 FOXK1 221937 forkhead box K1 nucleus Cellular component - ZNF93 81931 zinc finger protein 93 zinc ion binding Molecular function 2023909 MUC21 394263 mucin 21, cell surface associated integral component of membrane Cellular component - PFDN5 5204 prefoldin subunit 5 retina development in camera-type eye Biological process - GIMAP2 26157 GTPase, IMAP family member 2 GTP binding Molecular function - PVRL1 5818 poliovirus receptor-related 1 (herpesvirus entry mediator C) cell junction assembly Biological process - ITGA6 3655 integrin, alpha 6 leukocyte migration Biological process - AMOTL1 154810 angiomotin like 1 cytosol Cellular component - CACNA1G 8913 calcium channel, voltage-dependent, T type, alpha 1G subunit ion transmembrane transport Biological process - MTM1 4534 myotubularin 1 mitochondrion distribution Biological process 21135508 TLE6 79816 transducin-like enhancer of split 6 nucleus Cellular component - ARL8A 127829 ADP-ribosylation factor-like 8A beta-tubulin binding Molecular function 15331635 PSD3 23362 pleckstrin and Sec7 domain containing 3 trans-Golgi network Cellular component - TIPARP 25976 TCDD-inducible poly(ADP-ribose) polymerase face morphogenesis Biological process - EIF2AK2 5610 eukaryotic translation initiation factor 2-alpha kinase 2 evasion or tolerance by virus of host immune response Biological process - NDEL1 81565 nudE neurodevelopment protein 1-like 1 cytosol Cellular component - RPL37AP8 644338 ribosomal protein L37a pseudogene 8 structural constituent of ribosome Molecular function - VSTM4 196740 V-set and transmembrane domain containing 4 plasma membrane Cellular component - SPRY4 81848 sprouty homolog 4 (Drosophila) protein binding Molecular function 12027893 MAP3K14 9020 mitogen-activated protein kinase kinase kinase 14 innate immune response Biological process - RPS4X 6191 ribosomal protein S4, X-linked cellular protein metabolic process Biological process - GUCY1B3 2983 guanylate cyclase 1, soluble, beta 3 metal ion binding Molecular function - IL1B 3553 interleukin 1, beta regulation of I-kappaB kinase/NF-kappaB signaling Biological process 10748004 CYB5A 1528 cytochrome b5 type A (microsomal) small molecule metabolic process Biological process - FBXO43 286151 F-box protein 43 negative regulation of meiotic nuclear division Biological process - NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription Molecular function 24434510 WNT10A 80326 wingless-type MMTV integration site family, member 10A proteinaceous extracellular matrix Cellular component - LRP1 4035 low density lipoprotein receptor-related protein 1 apolipoprotein binding Molecular function 18635818 CELSR2 1952 cadherin, EGF LAG seven-pass G-type receptor 2 homophilic cell adhesion via plasma membrane adhesion molecules Biological process - NDNF 79625 neuron-derived neurotrophic factor extracellular matrix Cellular component - RNF139 11236 ring finger protein 139 ubiquitin-like protein transferase activity Molecular function 17016439 OR4F4 26682 olfactory receptor, family 4, subfamily F, member 4 olfactory receptor activity Molecular function - TYRO3 7301 TYRO3 protein tyrosine kinase spermatogenesis Biological process - LGI1 9211 leucine-rich, glioma inactivated 1 nervous system development Biological process 9879993 GSTM1 2944 glutathione S-transferase mu 1 xenobiotic metabolic process Biological process - ZNF486 90649 zinc finger protein 486 nucleus Cellular component - TSC1 7248 tuberous sclerosis 1 cell cortex Cellular component 10806479 SLC1A1 6505 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 cysteine transport Biological process 21123949 IGF1 3479 insulin-like growth factor 1 (somatomedin C) cellular protein metabolic process Biological process - HAO1 54363 hydroxyacid oxidase (glycolate oxidase) 1 cellular nitrogen compound metabolic process Biological process - ACTR8 93973 ARP8 actin-related protein 8 homolog (yeast) DNA repair Biological process - DACT2 168002 dishevelled-binding antagonist of beta-catenin 2 protein kinase A binding Molecular function - FREM1 158326 FRAS1 related extracellular matrix 1 integral component of membrane Cellular component - RRAGD 58528 Ras-related GTP binding D metabolic process Biological process - HDAC8 55869 histone deacetylase 8 mitotic cell cycle Biological process - RBL2 5934 retinoblastoma-like 2 transcription factor complex Cellular component - FHL1 2273 four and a half LIM domains 1 ion channel binding Molecular function 18281375 TAOK1 57551 TAO kinase 1 protein binding Molecular function 11733138 CSDE1 7812 cold shock domain containing E1, RNA-binding Golgi apparatus Cellular component - HIST2H2AA3 8337 histone cluster 2, H2aa3 DNA binding Molecular function - FOXJ2 55810 forkhead box J2 sequence-specific DNA binding Molecular function 10777590 PVRL2 5819 poliovirus receptor-related 2 (herpesvirus entry mediator B) cell-cell junction Cellular component 9845526 SEC31A 22872 SEC31 homolog A (S. cerevisiae) antigen processing and presentation of exogenous peptide antigen via MHC class II Biological process - IRF7 3665 interferon regulatory factor 7 interferon-beta production Biological process - AURKA 6790 aurora kinase A germinal vesicle Cellular component - JPH3 57338 junctophilin 3 plasma membrane Cellular component - PER2 8864 period circadian clock 2 negative regulation of protein ubiquitination Biological process - RARA 5914 retinoic acid receptor, alpha prostate gland development Biological process - NHS 4810 Nance-Horan syndrome (congenital cataracts and dental anomalies) lens development in camera-type eye Biological process - ITM2B 9445 integral membrane protein 2B integral component of organelle membrane Cellular component 10526337 TRMT12 55039 tRNA methyltransferase 12 homolog (S. cerevisiae) protein binding Molecular function 25416956 DPP4 1803 dipeptidyl-peptidase 4 regulation of cell-cell adhesion mediated by integrin Biological process 11772392 NCOA6 23054 nuclear receptor coactivator 6 cellular response to DNA damage stimulus Biological process 17500065 PSMD11 5717 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 membrane Cellular component 19946888 WBP2 23558 WW domain binding protein 2 positive regulation of gene expression, epigenetic Biological process 23233354 ALKBH7 84266 alkB, alkylation repair homolog 7 (E. coli) cellular response to DNA damage stimulus Biological process 23666923 WNT1 7471 wingless-type MMTV integration site family, member 1 positive regulation of Notch signaling pathway Biological process 16501043 NRP1 8829 neuropilin 1 growth cone Cellular component - ELFN1 392617 extracellular leucine-rich repeat and fibronectin type III domain containing 1 synapse organization Biological process - RIMS1 22999 regulating synaptic membrane exocytosis 1 visual perception Biological process - LCK 3932 LCK proto-oncogene, Src family tyrosine kinase protein C-terminus binding Molecular function 16245368 MYO6 4646 myosin VI filamentous actin Cellular component - SMC5 23137 structural maintenance of chromosomes 5 cellular senescence Biological process 17589526 SHROOM4 57477 shroom family member 4 stress fiber Cellular component - CASP8AP2 9994 caspase 8 associated protein 2 regulation of transcription, DNA-templated Biological process - UBL4A 8266 ubiquitin-like 4A cytosol Cellular componen