amyloid beta (A4) precursor-like protein 1
This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene aliases
APLP
Chromosome
19
Map location
19q13.1
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for APLP1
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| Sequence variants | |
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| Protein-Protein Interactions |
Sequence variants for APLP1
List of cell lines/tissues that have APLP1 sequence variants
List of pathways where APLP1 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for APLP1
Network key
Number of sequence variations per gene
Protein identification for APLP1
Browse by protein identification methods
| Identification method | Quantitative data available |
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