electron-transfer-flavoprotein, alpha polypeptide
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene aliases
EMA,
MADD
Chromosome
15
Map location
15q23-q25
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for ETFA
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| PTMs | |
| Protein entries | |
| Sequence variants | |
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| Protein-Protein Interactions |
Sequence variants for ETFA
List of cell lines/tissues that have ETFA sequence variants
List of pathways where ETFA is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for ETFA
Network key
Number of sequence variations per gene
Protein identification for ETFA
Browse by protein identification methods
| Identification method | Quantitative data available |
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