insulin-like growth factor 2
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
Gene aliases
C11orf43,
PP9974
Chromosome
11
Map location
11p15.5
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for IGF2
| Domains | |
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| PTMs | |
| Protein entries | |
| Sequence variants | |
| Cell lines/tissues | |
| Pathways involved in | |
| Protein-Protein Interactions |
Sequence variants for IGF2
List of cell lines/tissues that have IGF2 sequence variants
List of pathways where IGF2 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for IGF2
Network key
Number of sequence variations per gene
Protein identification for IGF2
Browse by protein identification methods
| Identification method | Quantitative data available |
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