matrix metallopeptidase 17 (membrane-inserted)
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008]
Gene aliases
MT4-MMP
Chromosome
12
Map location
12q24.3
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for MMP17
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| PTMs | |
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| Protein-Protein Interactions |
Sequence variants for MMP17
List of cell lines/tissues that have MMP17 sequence variants
List of pathways where MMP17 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for MMP17
Network key
Number of sequence variations per gene
Protein identification for MMP17
Browse by protein identification methods
| Identification method | Quantitative data available |
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