mutS homolog 2
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene aliases
COCA1,
FCC1,
HNPCC,
LCFS2
Chromosome
2
Map location
2p21
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for MSH2
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| PTMs | |
| Protein entries | |
| Sequence variants | |
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| Protein-Protein Interactions |
Sequence variants for MSH2
List of cell lines/tissues that have MSH2 sequence variants
List of pathways where MSH2 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for MSH2
Network key
Number of sequence variations per gene
Protein identification for MSH2
Browse by protein identification methods
| Identification method | Quantitative data available |
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