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poly(A) binding protein, cytoplasmic 1

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010]
Gene official symbol
PABPC1

Entrez gene ID
26986

Gene aliases
PAB1, PABP, PABP1, PABPL1

Chromosome
8

Map location
8q22.2-q23

Gene type
protein-coding

Gene Ontology (GO) terms enrichment




Database references
604679
8554
ENSG00000070756
OTTHUMG00000164779
VP_26986
ENSG00000070756-PABPC1


Statistics for PABPC1

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PTMs
Protein entries
Sequence variants
Cell lines/tissues
Pathways involved in
Protein-Protein Interactions



Sequence variants for PABPC1



List of cell lines/tissues that have PABPC1 sequence variants




List of pathways where PABPC1 is involved


Pathway name Pathway source

Protein-Protein Interaction Network for PABPC1



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Number of sequence variations per gene

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Protein identification for PABPC1


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Identification method Quantitative data available

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Isoform peptide details


Qualitative proteomic data





Post-translational modifications (PTMs) in PABPC1


Domains for PABPC1

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