toll-like receptor 10
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]
Gene aliases
CD290
Chromosome
4
Map location
4p14
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for TLR10
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| Protein-Protein Interactions |
Sequence variants for TLR10
List of cell lines/tissues that have TLR10 sequence variants
List of pathways where TLR10 is involved
| Pathway name | Pathway source |
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Protein-Protein Interaction Network for TLR10
Network key
Number of sequence variations per gene
Protein identification for TLR10
Browse by protein identification methods
| Identification method | Quantitative data available |
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