triosephosphate isomerase 1
This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
Gene aliases
HEL-S-49,
TIM,
TPID
Chromosome
12
Map location
12p13
Gene type
protein-coding
Gene Ontology (GO) terms enrichment
Database references
Statistics for TPI1
| Domains | |
|---|---|
| PTMs | |
| Protein entries | |
| Sequence variants | |
| Cell lines/tissues | |
| Pathways involved in | |
| Protein-Protein Interactions |
Sequence variants for TPI1
List of cell lines/tissues that have TPI1 sequence variants
List of pathways where TPI1 is involved
| Pathway name | Pathway source |
|---|
Protein-Protein Interaction Network for TPI1
Network key
Number of sequence variations per gene
Protein identification for TPI1
Browse by protein identification methods
| Identification method | Quantitative data available |
|---|